ライフサイエンスコーパス: inhibitory activity

1 E (0.50-0.44mg/mL) and AChE (7.93-5.83mg/mL) inhibitory activity.

2 an isomer showed acetylcholinesterase (AChE) inhibitory activity.

3 ylococci and major truncations abolished the inhibitory activity.

4 soforms and a functional deficiency in IL1RA inhibitory activity.

5 ng for specific stimulus-mediated control of inhibitory activity.

6 contrast, oleic acid alone had little to no inhibitory activity.

7 olecular docking was utilised to explain the inhibitory activity.

8 s in MDSC accumulation, survival, and immune-inhibitory activity.

9 tional residues abolished the toxin's growth-inhibitory activity.

10 izure onset zone, perhaps reflecting reduced inhibitory activity.

11 thod to screening drugs with potential DPP-4 inhibitory activity.

12 396 with Ala led to inactivation of MGAT4D-L inhibitory activity.

13 isolated PLA(2) toxins, demonstrating potent inhibitory activity.

14 4-L2A-encoded sPD-L1 lacks measurable T cell inhibitory activity.

15 f Treg cells in inflamed joints, and loss of inhibitory activity.

16 t2b and/or Wnt9b from CD8(+) CM reversed HIV inhibitory activity.

17 agents exerting partial FXR agonism and sEH inhibitory activity.

18 tor, or iniparib (n = 11), which has no PARP inhibitory activity.

19 and selective Brr2 inhibitor 9 with helicase inhibitory activity.

20 N-benzylated derivative showed enhanced Clk1 inhibitory activity.

21 CB to wheat bread significantly increased XO-inhibitory activity.

22 closan may be related to their mitochondrial inhibitory activity.

23 mbinations with greater than additive growth-inhibitory activity.

24 nding may be the molecular mechanism for its inhibitory activity.

25 cancer cell lines and for protein synthesis inhibitory activity.

26 explains their extensive contribution to the inhibitory activity.

27 ol content (GAE) and yeast alpha-glucosidase inhibitory activity.

28 predicted which genera were associated with inhibitory activity.

29 n and IC50 value of 1.60mg/ml for tyrosinase inhibitory activity.

30 es, revealing the structural basis for their inhibitory activity.

31 ACE-, alpha-glucosidase-, and Kunitz trypsin-inhibitory activity.

32 y test and only CSP4 and CSP6 exhibited high inhibitory activity.

33 CysC monomers and completely retain protease inhibitory activity.

34 tiestrogenic activity with the mitochondrial inhibitory activity.

35 Furthermore, the beverages showed a good ACE inhibitory activity.

36 rol infection and had higher parasite growth inhibitory activity.

37 rug-like molecules with potent in vitro TrmD inhibitory activity.

38 d adjunct culture addition increased the ACE inhibitory activity.

39 cterial activity by focusing on their growth inhibitory activity.

40 es with HYPK, a protein with intrinsic NAA10 inhibitory activity.

41 new functional foods with alpha-glucosidase inhibitory activity.

42 th broad, potent, and fungal-selective Hsp90 inhibitory activity.

43 iting HAA formation and explained partly the inhibitory activity.

44 the final enzyme-inhibitor complex with full inhibitory activity.

45 full-length MGAT4D-L, also inactivated MGAT1 inhibitory activity.

46 tionic polymers and demonstrated their nAChR inhibitory activity.

47 ossess both "plaque and tangle" reducing and inhibitory activity.

48 but with higher carotenoids content and ACE inhibitory activity.

49 in vitro CB1R antagonist activities and iNOS inhibitory activities.

50 howed an increase in the antioxidant and ACE inhibitory activities.

51 One compound (named RIm13) displayed a PCSK9 inhibitory activity 10-fold lower than the template comp

52 nd FSF samples; highest reduction in trypsin inhibitory activity (58%) was observed in the FS-sample.

53 mount of PT (10.00 mg phloroglucinol/g), PPO inhibitory activity (71.94%) and therefore selected for

54 Tyr-Pro had the highest ACE inhibitory activity (ACE IC50=5.21+/-0.94muM).

55 unds that we previously showed to have broad inhibitory activity across multiple Clostridioides diffi

56 as the most promising candidate with potent inhibitory activities against both PARP-1/2 and PI3Kalph

57 sEH inhibitors were screened to assess their inhibitory activities against cellular and humoral immun

58 el of viral membrane fusion, with a range of inhibitory activities against different HIV-1 Env isolat

59 zed molecule was generated with differential inhibitory activities against DprE1 and CYP2C9, which pr

60 at block these pathways can have independent inhibitory activities against HIV-1 infection and HIV-in

61 FLT3 inhibitory activities and subnanomolar inhibitory activities against MV4-11 and Molm-13 cells.

62 he new Top1 inhibitors also possess moderate inhibitory activities against tyrosyl-DNA phosphodiester

63 l at the 7- and 9-positions presented growth inhibitory activities against various human cancer cell

64 Comparisons of the enzyme inhibitory activity against a panel of HDAC isoforms rev

65 mide derivatives (26a-c), which possess high inhibitory activity against ALK2, excellent selectivity,

66 cetone extract of Undaria pinnatifida showed inhibitory activity against alpha-amylase, IC50 0.74+/-0

67 odified 2,3-difluoro-Neu5Ac showed increased inhibitory activity against bacterial sialidases.

68 CP26 exhibits a significant inhibitory activity against both DENV and ZIKV, providin

69 y activity against class IIa HDACs, but weak inhibitory activity against class I HDACs.

70 isoforms revealed these compounds had strong inhibitory activity against class IIa HDACs, but weak in

71 (DBPR112), which not only displayed a potent inhibitory activity against EGFR(L858R/T790M) double mut

72 nd photochemiluminescence technique, and the inhibitory activity against formation of fluorescent adv

73 Phenolic compounds, their inhibitory activity against fungal amylase and the occur

74 )acetamide derivatives, showed low nanomolar inhibitory activity against hCA II and hCA VII, isoforms

75 r of HDACs, AES-135, that exhibits nanomolar inhibitory activity against HDAC3, HDAC6, and HDAC11 in

76 -3503 and rac-cryptopleurine, exhibit potent inhibitory activity against hepatitis C virus (HCV) repl

77 ) using MTT assay, where they showed highest inhibitory activity against MCF-7.

78 E209 has potent nanomolar inhibitory activity against multiple strains of P. falci

79 oderate to weak cytotoxicity and significant inhibitory activity against nitric oxide (NO) production

80 DJK-5 showed stronger inhibitory activity against P. aeruginosa associated wit

81 lead optimized NSC319726 and its reasonable inhibitory activity against pathogens suggest advancing

82 l nonribosomal peptide congeners with potent inhibitory activity against prokaryotic translation init

83 ur compounds were further screened for their inhibitory activity against recombinant HDAC1-3, HDAC6,

84 PSOP displayed inhibitory activity against Staphylococcus aureus, Pseud

85 ain of the transcription factor STAT5 confer inhibitory activity against STAT3.

86 L7095) was also found to possess comparable inhibitory activity against T cells, indicating a potent

87 These compounds all displayed strong inhibitory activity against T.b. brucei but none of them

88 hat bind to the TDP1 active site and exhibit inhibitory activity against TDP1.

89 owed to be endowed with potent and selective inhibitory activity against the cancer-related human car

90 on of FXYD1 was shown to critically modulate inhibitory activity against the Na(+)/K(+) pump.

91 ed aporphinoid alkaloids that exhibit potent inhibitory activity against the opportunistic fungal pat

92 Analogues were shown to exhibit potent inhibitory activity against the Plasmodium falciparum cy

93 ic inhibitors was designed and evaluated for inhibitory activity against the programmed cell death-1/

94 anti-inflammatory properties and cell growth inhibitory activity against tumor cells.

95 domains 1 through 7 and possesses complement-inhibitory activity, also binds to N. gonorrhoeae The li

96 ntioxidant activity, di-peptidylpeptidase IV inhibitory activity among other and in vivo antihyperten

97 es to elucidate the molecular basis of their inhibitory activities and an unconventional resistance m

98 uents, resulting in compounds with high Top1 inhibitory activities and potent cytotoxicities in human

99 g them, compound 9u possessed nanomolar FLT3 inhibitory activities and subnanomolar inhibitory activi

100 gest that HAX-1 is a major mediator of PLN's inhibitory activity and a critical gatekeeper of SR calc

101 he GABAergic neurons can effectively enhance inhibitory activity and alter excitatory-inhibitory bala

102 antibacterial properties, polyphenoloxidase inhibitory activity and copper chelating activity.

103 protein co-precipitates showed improved ACE inhibitory activity and diminished antioxidant potency c

104 ied a set of compounds with the desired dual inhibitory activity and enhanced antiproliferative activ

105 protein co-precipitates showed decreased ACE inhibitory activity and increased antioxidant activities

106 oil nanoemulsion displayed higher mycotoxin inhibitory activity and less flavor impact on the final

107 med by our research group have reported high inhibitory activity and potential agricultural and medic

108 PNN removal caused reduced inhibitory activity and reset the network to a juvenile

109 eptide aldehyde, which bears potent protease inhibitory activity and selectively targets a subset of

110 y profile allowing enhancement of proteasome-inhibitory activity and specificity of BTZ by endocytosi

111 tral factor in the in vivo modulation of the inhibitory activity and suggest that the intrinsically d

112 eir MYC-inhibitory activity, topoisomerase I-inhibitory activity, and anticancer activity reveals a s

113 CB1R-inactive stereoisomer that retains iNOS inhibitory activity, and JD-5037, a peripherally restric

114 GF WSP possessed NO inhibitory activity, and the strongest was GF121.

115 f A- and D-ring modifications on 17beta-HSD3 inhibitory activity, androgenic effect, and metabolic st

116 ctivities like angiotensin converting enzyme inhibitory activity, antioxidant activity, di-peptidylpe

117 Inhibitory activities are possessed by MLAV VP35 and VP4

118 ds were evaluated for MAO-A, MAO-B, and AChE inhibitory activities as potential drug candidates for t

119 ith histones was independent of its protease inhibitory activity, as demonstrated by the use of react

120 nalysis of in vivo FLT3 inhibition by plasma inhibitory activity assay and indicated improved overall

121 d the chalcone-derivative 8 possessing Notch inhibitory activity at low micro molar concentration in

122 a lead compound, 34, that is endowed with an inhibitory activity at nanomolar concentrations, suitabl

123 connectivity, leading to altered excitatory/inhibitory activity balance.

124 rug mitoxantrone possesses significant DPP-4 inhibitory activity both in vitro and in vivo.

125 hese "hybrids" not only excel in outstanding inhibitory activity but also show high selectivity to PI

126 compounds (total phenolic compounds and ACE-inhibitory activity), changes in fatty acid composition

127 -precipitates showed increased alpha-amylase inhibitory activity compared to non-sonicated samples.

128 t time, we show that nasal IgG(4)-associated inhibitory activity correlates closely with the clinical

129 MGAT4D-L inhibitory activity could be partially transferred by at

130 Despite a strong DPAGT1 inhibitory activity, CPPB does not show cytotoxicity aga

131 Based on assessment of inhibitory activity, cytotoxicity, and target specificit

132 JMX0254) displayed the most potent and broad inhibitory activities, effective against DENV-1 to -3 wi

133 Biofilm inhibitory activity exhibited chemical properties of sho

134 s, DPPH, angiotensin-converting-enzyme (ACE) inhibitory activity, fatty acids profile, and volatile c

135 DH had no correlations (p > 0.05) with ACE inhibitory activity for all three legumes.

136 basophil activation and measurement of serum inhibitory activity for allergen-IgE binding to B cells

137 vailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide rib

138 Specificity and positive likelihood ratio of inhibitory activity for indicating remission status are

139 Growth inhibitory activity (GIA) was significantly higher in th

140 method was developed to assess alpha-amylase inhibitory activity (GOD method).

141 1.432mumol Trolox eq./mumol peptide) and ACE inhibitory activities (IC50=44-120muM).

142 unds 1 (X80), 22, and 24 displayed excellent inhibitory activity (IC50 of 0.82 +/- 0.18 muM and 1.3 +

143 subfraction, with enhanced alpha-glucosidase inhibitory activity (IC50=6.15mug/mL), with castalagin (

144 It also showed excellent inhibitory activities in FLT3-ITD-D835V and FLT3-ITD-F69

145 These quinolinol analogues demonstrated inhibitory activity in a cell-based model for SNAP-25 cl

146 entanoate shows a potent histone deacetylase-inhibitory activity in CD4(+) T cells, thereby reducing

147 ntibodies showed more potent parasite growth inhibitory activity in combination than on their own, su

148 SD-36 achieves nanomolar cell growth inhibitory activity in leukemia and lymphoma cell lines

149 tes significantly enhanced and prolonged the inhibitory activity in multiple mouse and human cell lin

150 IgG-associated inhibitory activity in nasal fluid and serum was signifi

151 imulation-evoked responses of excitatory and inhibitory activity in networks, extending the growing l

152 liminary evaluation of the CYP3A4 and CYP2D6 inhibitory activity in optimized ligands evidenced weak

153 le-based peptidomimetic that has shown PCSK9 inhibitory activity in the micromolar range.

154 The organometallics showed inhibitory activity in the nanomolar range against histo

155 Virulence inhibitory activity in the RND-negative background resul

156 exyl ether (HT C6) exhibited the most potent inhibitory activity in vitro, activating as well apoptos

157 ranatumine A, a limonoid alkaloid with PTP1B inhibitory activity, in ten steps.

158 aR isomers of 1 had a critical effect on the inhibitory activity, indicating that modulation of the c

159 Treg inhibitory activity is a promising prognostic marker and

160 the effect on the fatty acid profile and ACE inhibitory activity is dependent on the process paramete

161 The tumor inhibitory activity is greatly amplified when the Pt NPs

162 Treg inhibitory activity is inversely correlated with the DAS

163 Starting from quinoline 2 with weak ATR inhibitory activity, lead optimization efforts focusing

164 n-3 in a BTB-dependent manner, its NF-kappaB inhibitory activity mapped to the Kelch domain, which al

165 Transient imbalances in excitatory and inhibitory activity may provide a general mechanism for

166 dy the capacity of macrophages to circumvent inhibitory activity mediated by CD47 on cancer cells.

167 This study reports, for the first time, the inhibitory activities of a series of steroidal and nonst

168 We propose that at least some of the inhibitory activities of alphaSNAP ensure that neurotran

169 igh-throughput screening was used to measure inhibitory activities of BKIs against C. parvum in vitro

170 The antioxidant, antitumor and alpha-amylase inhibitory activities of exopolysaccharide-C47 product r

171 The strong inhibitory activities of growth hormone-releasing hormon

172 Here, we tested the inhibitory activities of the antiviral interferons of ty

173 The antioxidant and ACE-inhibitory activities of the extracted proteins were ini

174 The inhibitory activities of the LEKTI domain 4 (D4) and D6

175 AR inhibitory activities of the novel compounds were charac

176 oxidant, alpha-glucosidase and alpha-amylase inhibitory activities of various crudes and fractions ob

177 ule 11 (653-47) that can potentiate the CREB inhibitory activity of 666-15 although 653-47 alone does

178 Here, we report the inhibitory activity of a flavone rich extract "430D-F5"

179 The biofilm-inhibitory activity of antibiotics and/or the anti-biofi

180 he absence of vivax invasion assays, binding-inhibitory activity of antibodies has been reported to b

181 ion.IMPORTANCE The greater ex vivo antiviral inhibitory activity of CD8(+) T cells from elite control

182 natural EEEV infection with potent (<20 pM) inhibitory activity of EEEV.

183 mics simulation) methods to evaluate the HPA inhibitory activity of eight water-soluble vitamins, for

184 The inhibitory activity of endogenous IL1RA was assessed usi

185 The antifungal activity and mycotoxin inhibitory activity of essential oils in both bulk and n

186 ition of mycotoxin production, the mycotoxin inhibitory activity of essential oils was enhanced consi

187 The importance of assessing the inhibitory activity of extracts under simulated intestin

188 city of buckwheat flours was noted while the inhibitory activity of fermented flours against AGEs for

189 ely affected angiotensin I-converting enzyme inhibitory activity of fermented lentil (p<.0001).

190 enolic composition and xanthine oxidase (XO) inhibitory activity of green coffee beans (GCB) and whol

191 een of a series of metal salts showed marked inhibitory activity of group 11 and 12 metals against th

192 of this study was to evaluate the potential inhibitory activity of guarana extracts, after digestion

193 The ACE-inhibitory activity of HG showed the highest stability a

194 (DH), angiotensin-I converting enzyme (ACE) inhibitory activity of hydrolysates showed significant d

195 Thus, the inhibitory activity of L-cIDPR analogues appears to depe

196 We demonstrate the direct inhibitory activity of LegC8 effector on TBSV replicatio

197 aled that the D6 D386N mutation affected the inhibitory activity of LEKTI on KLK5 but not KLK7.

198 h atopic dermatitis (AD) affect the protease inhibitory activity of LEKTI or its susceptibility to me

199 All the extracts showed inhibitory activity of lipase, although those from T. mo

200 gulation appears to be the foundation of the inhibitory activity of many of the commercial herbicides

201 We studied the inhibitory activity of methylene blue (MB) gamma-carboli

202 However, the mechanism of this inhibitory activity of NS5A remains partly characterized

203 ieves CDK2 inhibition by suppressing the CDK inhibitory activity of p27.

204 Here, we characterize the inhibitory activity of P2X1 receptor antagonists, NF279

205 tions as a receptor antagonist, blocking the inhibitory activity of PD-L1 bound on cellular or exosom

206 cells with NAC completely abrogated the NKA inhibitory activity of plumbagin and atovaquone.

207 radical scavenger, N-acetylcysteine, the NKA inhibitory activity of plumbagin was abrogated.

208 The angiotensin I-converting enzyme (ACE) inhibitory activity of protein hydrolysates from tilapia

209 the RHOA and MAP3K4 binding partners and the inhibitory activity of RAC1.

210 Interestingly, unlike wild-type SBV, the inhibitory activity of SBVDeltaNoLS toward RNA Pol II tr

211 The inhibitory activity of soluble and insoluble starch (0-5

212 The FXIIIa inhibitory activity of the analogues was retained, which

213 The latter blocks the inhibitory activity of the autoinhibitor domain.

214 tioxidant capacity and the alpha-glucosidase inhibitory activity of the duodenal extract correlated w

215 We show that the remarkably rapid growth inhibitory activity of the ICE toxin is a correlate of a

216 o gastrointestinal digestion reduced the ACE inhibitory activity of the M hydrolysate but enhanced it

217 The inhibitory activity of the non-digested and digested sam

218 Further investigations into the growth-inhibitory activity of the two bombolitins were performe

219 exposed to cigarette smoke extract lost the inhibitory activity of their secreted EVs.

220 The number and inhibitory activity of Treg are higher in the clinical r

221 y scaffold hopping and exploiting the potent inhibitory activity of various warhead groups to obtain

222 ) derivative 1 (RM-532-105) has shown strong inhibitory activity on 17beta-HSD3, but needs to be impr

223 fort to find modafinil analogues with higher inhibitory activity on and selectivity toward the dopami

224 w much endogenous HAX-1 contributes to PLN's inhibitory activity on calcium cycling is unknown.

225 Inhibitory activity on CCR3 signaling was assessed in vi

226 creases p27 levels, it also attenuates p27's inhibitory activity on CDK2 and thereby contributes to i

227 sphodiesterase 4 (PDE4) as well as for their inhibitory activity on cell proliferation in A375 melano

228 N-methylation did not alter flecainide's inhibitory activity on human cardiac sodium channels exp

229 ssociated with AD, may cause a disruption of inhibitory activity on KLK5 or enhance the degradation b

230 nder certain circumstances, it also shows an inhibitory activity on metastatic processes, and the cau

231 Six flavones (2, 3, 6-8, 12) showed potent inhibitory activity on OAT1, while seven flavones (2, 3,

232 seven flavones (2, 3, 6-9, 12) showed marked inhibitory activity on OAT3, with IC(50) <= 10.0 uM.

233 Their inhibitory activity on pancreatic lipase and alpha-amyla

234 ed comparable antioxidant capacity, stronger inhibitory activity on pancreatic lipase and comparable

235 dissociates it from 5'UTRs and relieves its inhibitory activity on RP mRNA translation.

236 tor approved for the treatment of MF, had no inhibitory activity on this pathway.

237 ch ranged from 11.2- to 549.8-fold-decreased inhibitory activity over that of their parental viruses.

238 sociated at the MYC promoter, supporting the inhibitory activity PGC1alpha.

239 SosA accumulation and a strong cell division inhibitory activity, phenotypically similar to expressio

240 tivirus-mediated silencing of MIA3 (melanoma inhibitory activity protein 3) in VSMCs resulted in lowe

241 PSMA inhibitory activities ranged from 0.10 to 17 nM.

242 Here, we tested whether GABA-derived inhibitory activity regulates the balance of lick- and t

243 This inhibitory activity requires the presence of cGAS, but i

244 3 and found they were able to block serpin-3 inhibitory activity, resulting in suppression of inhibit

245 t effect and angiotensin I-converting enzyme inhibitory activity), rheological, and water mobility by

246 in olfactory processing by orchestrating OB inhibitory activities.SIGNIFICANCE STATEMENT Neuronal mo

247 emicarbazones (1-5): one of them revealed an inhibitory activity stronger than kojic acid, used as re

248 olerated substitutions without loss of RD3's inhibitory activity, substitutions in two distinct narro

249 A biochemical assessment of the inhibitory activity suggested that the S. caprae autoind

250 e synthase (iNOS) and cyclooxygenase (COX-2) inhibitory activity than an equivalent mixture of flavon

251 and pepsin hydrolysates exhibited higher ACE-inhibitory activity than HT (P<0.05).

252 hibit SARS-CoV-2 replication with a stronger inhibitory activity than Remdesivir within the same expe

253 ompounds 7j, 7i, 6e, 7f, and 3 showed higher inhibitory activity than the initial lead, with K(i) val

254 er alpha-amylase, alpha-glucosidase, and ACE inhibitory activity than the pasteurized product, simila

255 sal allergen-specific IgG(4) antibodies with inhibitory activity that correlates closely with clinica

256 nity than wild-type HVEM and retained potent inhibitory activity that reduced T-cell receptor, B-cell

257 y seven tick proteins with putative thrombin inhibitory activity that we predict to be posttranslatio

258 rom HTS were further screened for their AChE inhibitory activity, the most widely investigated target

259 ally define the UbV interaction, explain its inhibitory activity through binding the surface on the A

260 ical inhibitors, we predicted their putative inhibitory activities to trypsin/chymotrypsin/elastase-l

261 reatment with an alcohol solvent transferred inhibitory activity to the wash, and mass spectrometry r

262 f indenoisoquinoline analogues for their MYC-inhibitory activity, topoisomerase I-inhibitory activity

263 Besides the preservation of the TA inhibitory activity toward L. monocytogenes, the possibi

264 evolutionary divergence, various TIMPs lost inhibitory activity toward some metalloproteinases, spec

265 ed quercetin (compound 6) that exerts potent inhibitory activity toward the platelet 12-LO pathway (I

266 ses and also finding compound 21m with 27 nM inhibitory activity toward thrombin.

267 othelial progenitor EP cells) and the kinase inhibitory activity (toward both isolated kinases and EP

268 -free supernatants (CFS) exhibited potential inhibitory activities towards alpha-amylase, alpha-gluco

269 osed of Az and geldanamycin, which have high inhibitory activities towards both Hsp70 and Hsp90, exhi

270 wever, the Az and imatinib hybrids have weak inhibitory activities towards Hsp70 and Abl, and display

271 stance to gastrointestinal digestion and the inhibitory activity towards endothelial cell migration.

272 d from RA patients for determination of Treg inhibitory activity using a co-culture system.

273 mpounds (DPPD, Total Phenolic Compounds, ACE-inhibitory activity values), fatty acid composition, and

274 The range of the values for alpha-amylase inhibitory activity was 10.03-23.33mM, whereas the value

275 The magnitude of the inhibitory activity was 93% (P < .001) in nasal fluid co

276 inhibitors of ACE, WPH with the highest ACE inhibitory activity was analysed using Sephadex G-75 gel

277 The highest DPP-IV inhibitory activity was found with the amino acid Tyr (D

278 Higher ACE-inhibitory activity was generated in the trypsin and pep

279 The FGF inhibitory activity was mapped to the thrombospondin typ

280 Inhibitory activity was measured by IgE-facilitated alle

281 activity whereas a negative impact on lipase inhibitory activity was observed (p<.0001).

282 t relationship between SCCD pressure and ACE inhibitory activity was observed, with 34.63, 38.75, and

283 The highest dipeptidyl peptidase IV inhibitory activity was obtained by the combination of t

284 Without PNNs, inhibitory activity was reduced, whereas spiking variabi

285 Growth inhibitory activity was significantly higher in the sero

286 alf of TIMP-1 is sufficient for TIMP-1's MMP-inhibitory activity, we propose that those C-terminal am

287 total phenolic content, antioxidant and ACE inhibitory activities were evaluated at storage time and

288 Relative inhibitory activities were rationalized by X-ray analysi

289 lase and angiotensin converting enzyme (ACE) inhibitory activities were successfully identified using

290 lase, alpha-glucosidase and aldose reductase inhibitory activity were assessed.

291 as 10.03-23.33mM, whereas the values for ACE inhibitory activity were of 1.52-31.88muM.

292 i-parasitic, and acetylcholinesterase (AChE) inhibitory activity, were detected in apples.

293 he lead molecule allowed improvement of IDO1 inhibitory activity while minimizing off-target liabilit

294 YP3A4 and CYP2D6) demonstrated insignificant inhibitory activity, while in vitro experiments in three

295 N-FIV (3-1kDa) fractions showed the best ACE-inhibitory activities with IC50 values of 53.31 and 75.0

296 3a and 7c exhibited promising inhibitory activities with MICs ranging 1-8 mug/mL again

297 IMP3 (Timp3(S179C/S179C)) showed reduced MMP inhibitory activity with an increase in MMP2 activity an

298 The EtOAc and MeOH extracts presented higher inhibitory activity with respect to alpha-amylase and ty

299 nes and primary cells and showed synergistic inhibitory activity with the chemotherapy drug pemetrexe

300 e (ACE) and dipeptidyl peptidase IV (DPP-IV) inhibitory activities, with inhibition of ACE being stro