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1 ombination with ciprofloxacin (2.5 x minimum inhibitory concentration).
2 by peptide concentrations below the minimal inhibitory concentration.
3 ll molecules and measured their half-maximal inhibitory concentration.
4 ylamide (TM(inh)-23) with 30 nM half-maximal inhibitory concentration.
5 well below the protein-binding-adjusted 90% inhibitory concentration.
6 cern the molecular mechanism and the minimum inhibitory concentration.
7 aluated by disk diffusion assays and minimum inhibitory concentration.
8 tro identified compounds with potent minimum inhibitory concentrations.
9 he half maximal (IC50) and the minimal (MIC) inhibitory concentrations.
10 types, as well as metadata including minimum inhibitory concentrations.
11 tained over a period of 7 days above minimal inhibitory concentrations.
12 ssess its effect on the antibiotics' minimum inhibitory concentrations.
13 obial compounds which it contains are at non-inhibitory concentrations.
15 n the MCL cell lines with lower half-maximal inhibitory concentration (0.1-0.5 muM), pevonedistat ind
16 DTG concentrations exceeded the in vitro 50% inhibitory concentration (0.21 ng/mL) by a median of 214
18 EO-Nm exhibited improved antifungal (minimum inhibitory concentration = 0.08 muL/mL) and antiaflatoxi
20 O4(-) uptake via hNIS in vitro (half-maximal inhibitory concentration, 0.55-0.56 muM (in comparison w
23 ost promising properties (e.g., half-maximal inhibitory concentration, 19.2 +/- 5.8, tumor-to-muscle
24 nhibitory concentration (>= fT > 1 x minimum inhibitory concentration); 2) were above four times the
25 showed a selective inhibitory profile and an inhibitory concentration 50 (IC(50)) of <0.003 muM for b
27 9726 was 35-800-fold higher than the Minimum Inhibitory Concentration 50% (MIC50 values), which indic
28 nternalization), high affinity (half-maximal inhibitory concentration, 6.4-12.7 nM), and significant
29 variants of the CXCR4 receptor (half-maximal inhibitory concentration, 8 nM [human]/2 nM [murine]) an
30 a novel high-affinity radioligand (human 50% inhibitory concentration = 9.6 nM) for the PAM site of m
31 bidity detection accuracy of 98.21%, minimum-inhibitory-concentration accuracy of 95.12%, and a drug-
33 that exhibited a marked increase in the 50% inhibitory concentrations against all tested NAIs (827-,
35 P disruption corresponded with lower minimum inhibitory concentrations against the Gram-positive Stap
36 ions for various dosing regimens and minimal inhibitory concentration and calculated the probability
38 concentrations above their protein-adjusted inhibitory concentration and retained their physical and
39 istant mutants increase the in vitro minimum inhibitory concentration and the in vivo 99% effective d
40 ding and increased both the in vitro minimum inhibitory concentration and the in vivo effective dose
42 bit heritable multidrug increases in minimal inhibitory concentrations and decreases in drug-dependen
44 ibitory concentration (>= % fT > 4 x minimum inhibitory concentration); and 3) were always above the
45 trahigh neutralization potency (half-maximal inhibitory concentration as low as 0.058 ng/ml) and may
46 ill be used, along with the existing minimum inhibitory concentration, as a standard for the in vitro
47 chieve day 2 area under the curve to minimum inhibitory concentration (AUC/MIC) thresholds previously
49 er the concentration time curve over minimal inhibitory concentration (AUC24/MIC) ratios, and emergen
50 er the concentration time curve over minimal inhibitory concentration (AUC24/MIC) ratios, and emergen
51 ssociated with elevated azithromycin minimum inhibitory concentration (AZIem), characterized by a mos
52 t fecal concentrations greater than parasite inhibitory concentrations correlate best with effective
53 odels confirmed that a high triazole minimal inhibitory concentration corresponded with triazole trea
57 e 'elite' activity with 50 and 99% effective inhibitory concentrations (EC(50) and EC(99)) of less th
59 of Na(v)1.5 (874 and 231 umol/L half-maximal inhibitory concentration, fast and late sodium current).
61 oncentrations above the protein-adjusted 90% inhibitory concentration for 25 weeks with substantial t
62 t one trough value was above the 90% maximal inhibitory concentration for dolutegravir and HIV viral
63 ation spent over 64 mg/L (4-fold the minimal inhibitory concentration for Pseudomonas aeruginosa) wer
64 ease of >3 doubling dilutions in the minimum inhibitory concentration for third-generation cephalospo
65 ble EVG concentrations that exceeded the 50% inhibitory concentration for wild-type HIV, suggesting t
66 SF was >0.51 ng/mL (proposed CSF 50% maximal inhibitory concentration for wild-type virus) in all sub
67 l derived from the clay exceeded the minimum inhibitory concentrations for E. coli under acidic condi
70 t drug concentrations inside caseum and high inhibitory concentrations for this bacterial subpopulati
71 hibitory concentration (>= 100% fT > minimum inhibitory concentration) for the first 72 hours of anti
72 istin susceptibility by reducing the minimum inhibitory concentration from 8 to 0.5 mug/ml, 4-fold be
73 ositive predictive value compared to minimum inhibitory concentrations generated by commercial method
74 igecycline therapy given tigecycline minimum inhibitory concentration greater than 2 mg/L compared wi
77 ation); 2) were above four times the minimum inhibitory concentration (>= % fT > 4 x minimum inhibito
78 ation); and 3) were always above the minimum inhibitory concentration (>= 100% fT > minimum inhibitor
79 1) were above the target organism's minimum inhibitory concentration (>= fT > 1 x minimum inhibitory
80 e arms showed improved potency (half-maximal inhibitory concentration (IC(50)) <1 muM) and selectivit
81 showed a 60-fold lower shifted-half-maximal inhibitory concentration (IC(50)) for CYP4Z1 compared to
82 d diflunisal derivatives showed half-maximal inhibitory concentration (IC(50)) values 1 order of magn
83 CoV-2 infection of Vero E6 cells with median inhibitory concentration (IC(50)) values between 24 pico
84 e most potent bNAbs have median half-maximal inhibitory concentration (IC(50)) values in the nanomola
85 n antiproliferative agent, with half-maximal inhibitory concentration (IC(50)) values in the single-
86 egions isolated during VF displayed high 50% inhibitory concentration (IC(50)) values relative to tho
88 or estimating the potency [e.g. half-maximum inhibitory concentration (IC) known as IC50] of anti-can
89 RBD neutralized the virus with half-maximal inhibitory concentrations (IC(50) values) as low as 2 ng
90 inhibitors with sub-micromolar half-maximal inhibitory concentrations (IC(50)) in a LOX enzyme activ
91 erative activity in Hep3B cells, with median inhibitory concentrations (IC(50)) of 0.5 ug/mL, 7.49 ug
93 d five human cancer cells, with half maximal inhibitory concentrations (IC(50)s) of 13.2~37.3 muM.
95 ility in serum), PSMA affinity (half-maximal inhibitory concentration [IC(50)] range 19.2 +/- 5.8-175
96 se is inhibited by sulfide with half-maximal inhibitory concentration IC50 = 1.1 +/- 0.1 muM, under i
97 ent genotypes, and showed differences in 50% inhibitory concentration (IC50 ) correlating with clinic
100 viral entry process with a submicromolar 50% inhibitory concentration (IC50) (IC50 = 0.61 +/- 0.23 mu
102 y (ORAC) assays with a measured half-maximal inhibitory concentration (IC50) for the best case of 1.5
107 an and rat P2X7R orthologs, the half maximal inhibitory concentration (IC50) of JNJ-54173717 was 4.2
108 h isoeugenol showing the lowest half-maximal inhibitory concentration (IC50) values of mycelium growt
109 re determined for 28 drugs with half-maximal inhibitory concentration (IC50) values ranging from 1.03
110 on of 11, all complexes exhibited 50% growth inhibitory concentration (IC50) values that were less th
111 of kelch13 mutations, higher piperaquine 50% inhibitory concentration (IC50) values, and lower mefloq
113 ing antioxidant activities, the half maximal inhibitory concentration (IC50) was 215.86 mug/ml and Tr
115 highest increase in oseltamivir half-maximal inhibitory concentration (IC50), and E119D conferred the
116 h mitochondrial O2 consumption [half maximal inhibitory concentration (IC50): 3.8muM] and ATP synthes
117 des, LPVP and MPVQA, had DPP-IV half maximal inhibitory concentrations (IC50) of 87.0+/-3.2 and 93.3+
118 ld higher IFNbeta (P < 0.00001) half-maximal inhibitory concentrations (IC50) than did donor isolates
122 rains of Plasmodium falciparum (half maximal inhibitory concentration [IC50] = 1-2 uM), suggesting th
123 azyl (DPPH) radical quenching potential (50% inhibitory concentration, IC50 approximately 0.59mg/mL)
124 authentic SARS-CoV-2 virus with half-maximal inhibitory concentrations (IC50s) in the 10- to 100-ng/m
125 anti-Plasmodium properties with half-maximal inhibitory concentrations (IC50s) of 2.9 +/- 2.4, 10.7 +
127 iations (CNVs) with in-vitro piperaquine 50% inhibitory concentrations (IC50s), and tested whether th
128 mosomes were associated with piperaquine 90% inhibitory concentrations (IC90) in a genome-wide analys
130 ic and drug-resistant bacteria, with minimal inhibitory concentrations in a sub-micromolar range.
131 after gel application and remained above 95% inhibitory concentrations in rectal fluids at 24 hours.
133 iotic mechanisms of action and resistance at inhibitory concentrations in the lab and in the clinic.
136 bility testing, and determination of minimum inhibitory concentration is conventionally performed by
137 ynamic target of fT greater than 1 x minimum inhibitory concentration led to similarly high rates of
138 copies per mL and a BMS-626529 half-maximum inhibitory concentration lower than 100 nmol/L were rand
139 hereas 221-7 was borreliacidal (half maximal inhibitory concentration, < 1 nM) against B. burgdorferi
140 ing recombinantly expressed enzymes, minimum inhibitory concentration measurements, steady-state enzy
141 istance, which is measured using the minimum inhibitory concentration metric, tolerance and persisten
142 ates, there were 10 with ceftriaxone minimum inhibitory concentration (MIC) >/=0.06 mg/L and azithrom
143 nd 11.8% (group B) of patients had a minimum inhibitory concentration (MIC) >2 mug/mL to penicillin.
144 ore potent antimicrobial agents [VRE minimum inhibitory concentration (MIC) = 0.01-0.005 mug/mL] with
145 ctive against Staphylococcus aureus [minimum inhibitory concentration (MIC) = 4 ug/mL], while the blu
146 iperacillin/tazobactam and meropenem minimum inhibitory concentration (MIC) and beta-lactam resistanc
147 fungal activity was studied, and the minimal inhibitory concentration (MIC) and minimal fungicidal co
148 vity was determined by measuring the minimum inhibitory concentration (MIC) and minimum bactericidal
150 ow classic metrics like the IC50 and minimal inhibitory concentration (MIC) are dubious proxies for u
151 ains were constructed to perform the minimum inhibitory concentration (MIC) assays, which indicated t
153 tibacterial activities, lowering the minimum inhibitory concentration (MIC) by more than one order of
154 istance but genotypic DST (gDST) and minimum inhibitory concentration (MIC) could be beneficial.
156 resulted in a 2-fold increase in the minimal inhibitory concentration (MIC) for the hybrid, while mox
157 rs enable accurate prediction of the minimum inhibitory concentration (MIC) in 60 min (p < 0.03).
158 vations that the traditional test of minimum inhibitory concentration (MIC) is not informative enough
159 zithromycin resistance affecting the Minimal Inhibitory Concentration (MIC) levels of 91.2% isolates
160 ected by laboratory estimates of the minimum inhibitory concentration (MIC) needed to prevent bacteri
161 Compound 1f was most potent with a minimal inhibitory concentration (MIC) of 12.5 mug/mL and an Mtb
163 osis; the most potent compound had a minimum inhibitory concentration (MIC) of 52 nM and was not cyto
166 oncentrations of LL-37 increased the minimum inhibitory concentration (MIC) of S. aureus towards vanc
168 fficacy was linked to the AUC0-24 to minimum inhibitory concentration (MIC) ratio (r(2) = 0.98).
170 cin (VAN) area under the curve (AUC)/minimum inhibitory concentration (MIC) to ensure clinical effica
171 Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) value as low as 0.5 mug/m
172 ested fungal strains, with excellent minimum inhibitory concentration (MIC) values against non-albica
173 tivity of these dihydropyridomycins (minimum inhibitory concentration (MIC) values around 2.5 muM), w
175 ycobacterium tuberculosis H37Rv with minimum inhibitory concentration (MIC) values of 9.65 and 22.28
177 d very potent activities [sub-mug/mL minimum inhibitory concentration (MIC) values] against Gram-posi
180 pared its spectrum of inhibition and minimum inhibitory concentration (MIC) with that of nisin A and
181 igma correlates not with a peptide's minimum inhibitory concentration (MIC), but rather its ability t
190 sed on 735 literature data points of minimum inhibitory concentrations (MIC) of Plantae, Bacteria, an
193 of two circular micropumps, and the minimum inhibitory concentrations (MIC) were then determined via
194 strains as minimal bactericidal and minimal inhibitory concentrations (MIC), are independent of bact
195 lity breakpoint for enterococci (ie, minimum inhibitory concentration [MIC] <=4 mg/L) is appropriate.
196 rofloxacin concentrations (i.e., 50x minimum inhibitory concentration, MIC), despite the lack of obse
197 s were more likely to have meropenem minimum inhibitory concentrations (MICs) >/=16 microg/mL, while
198 l demonstrated elevated azithromycin minimum inhibitory concentrations (MICs) >256 mug/mL and elevate
200 ever, we additionally found that the minimum inhibitory concentrations (MICs) against fluoroquinolone
201 in, and ciprofloxacin geometric mean minimum inhibitory concentrations (MICs) as the outcome variable
203 protein production when determining minimum inhibitory concentrations (MICs) especially by broth dil
207 -kill kinetic assay was performed at minimum inhibitory concentrations (MICs) in all planktonic strai
209 t E. faecium strains with daptomycin minimum inhibitory concentrations (MICs) in the higher end of su
212 ns nontoxic to mammalian cells), the minimum inhibitory concentrations (MICs) of imipenem against cli
213 ured Neisseria species, and measured minimum inhibitory concentrations (MICs) to ciprofloxacin, cefix
216 ma drug concentrations and bacterial minimum inhibitory concentrations (MICs) were used to determine
222 ity to S. malaysiensis and exhibited minimum inhibitory concentration of 0.024 ug/mL against methicil
224 dies manifest that BM30 (with a half-maximal inhibitory concentration of 0.89 +/- 0.10 muM) is a comp
225 xchange mediated by mouse pendrin with a 50% inhibitory concentration of 1-3 microM, without affectin
226 ies against mTOR and HDAC1 with half-maximal inhibitory concentration of 1.2 and 0.19 nM, respectivel
227 ith a KD of 76 nM against BioA and a minimum inhibitory concentration of 1.7 muM (0.6 mug/mL) against
228 teria monocytogenes: cIsf pool had a minimum inhibitory concentration of 10microg/ml prenylated compo
234 this blocking agent revealed a half maximal inhibitory concentration of 40 nM which is comparable to
237 Ga-HZ220 had a lower affinity for GRPr (inhibitory concentration of 50% [IC50], 21.4 +/- 7.4 nM)
239 pharmacodynamic modeling estimated a minimum inhibitory concentration of 83 ng/mL and a minimal paras
241 18 h incubation time and reduced the minimal inhibitory concentration of amphotericin B or fluconazol
243 uced cell proliferation and reduced the IC50 inhibitory concentration of chemotherapeutic drugs in vi
247 evaluate the cytopathic effect, the minimum inhibitory concentration of ten antimicrobial agents, th
250 pathogenic Aspergillus spp. revealed minimal inhibitory concentrations of </=0.06 microg/mL-greater p
254 FR-alpha-positive KB cells gave half-maximal inhibitory concentrations of 27.1 +/- 3.7 and 23.8 +/- 4
255 0 epistatic pairs that influence the minimum inhibitory concentrations of 5 different antibiotics in
257 cterial susceptibility testing shows minimum inhibitory concentrations of 80 mg/mL against a model Es
258 the tested pathogenic bacteria with minimum inhibitory concentrations of 8~32 ug/mL, while compound
260 coli, which we use to test the effect of sub-inhibitory concentrations of common antibiotics on the e
265 , marcAST can accurately measure the minimum inhibitory concentrations of reference bacterial strains
267 P. aeruginosa in macrophages exposed to sub-inhibitory concentrations of the fluoroquinolone antibio
274 sistant isolates had alarmingly high minimum inhibitory concentration shifts (16- to >128-fold) compa
278 time that faropenem persisted above minimum inhibitory concentration (TMIC) on the moxifloxacin-line
279 vels far exceeding the cellular half maximal inhibitory concentration values (>100,000-fold), and apt
280 ted strains of M. tuberculosis, with minimum inhibitory concentration values as low as 0.03 muM (0.01
281 d sensitivity to dasatinib with half maximal inhibitory concentration values below 20 nM was detected
282 ed with significantly higher PI half-maximum inhibitory concentration values compared with other mole
284 ase (by 64-128-fold) the tigecycline minimal inhibitory concentration values for Escherichia coli, Kl
285 s, E. coli, and S. typhimurium, with minimum inhibitory concentration values from 14,211 to 3,553 ug.
286 :blood penetration ratios were above the 50% inhibitory concentration values in almost 100% of cases.
287 , four promising candidates emerged with 50% inhibitory concentration values in the 3 to 26 muM range
289 ounds inhibited M(pro), showing half-maximal inhibitory concentration values that ranged from 0.67 to
291 idyl-prolyl isomerase activity (half maximal inhibitory concentration values, 0.2-16.2 mumol/L) and,
292 ng, by preventing mPTP opening (half maximal inhibitory concentration values, 1.4-132 mumol/L) in a c
299 ark compared with T greater than 4 x minimum inhibitory concentration with standard antibiotic dosing
300 ugh to promote tungstate solubility to reach inhibitory concentrations, without precipitation, and co