ライフサイエンスコーパス: initial step

1 he 40S P site remains unoccupied during this initial step.

2 tion for the observed cis selectivity in the initial step.

3 redundancy of the enzymes involved in these initial steps.

4 uced by a cascade of two catalytic steps: an initial step acting at unattached kinetochores to produc

5 III subdomains under force may constitute an initial step along the transition pathway.

6 We take an initial step along this path proposing an encoded qubit

7 d, that there is loose coupling between this initial step and activation of the TM domain, and that a

8 es: Mre11-Rad50-Xrs2, which functions at the initial step and also stimulates the two processive path

9 olecular motors to facilitate transport, the initial steps and neuronal responses to infection are po

10 merous times in all domains of life, yet its initial steps are poorly understood.

11 improved mutagenesis analysis pipeline, the initial steps are the same as in the supF mutation assay

12 nd H2O2 via a two-electron transfer with the initial step being rate-limiting (k = 26 M(-1) s(-1) at

13 In an initial step, DNA traverses an N-terminal kleisin gate t

14 Given that pollination is the crucial initial step during plant reproduction, understanding th

15 ences of host association for symbionts, the initial steps facilitating their incorporation into a ho

16 formation occurs via alkene insertion as the initial step for all three metals, without involving hig

17 With the aim of investigating the initial step for C-F hydroxylation, two new ligands were

18 ipid desorption from membranes, likely as an initial step for lipid transfer, and binds to Tom40, sug

19 l for MCC development: GMNC functions in the initial step for MCC precursor specification.

20 we propose that such clustering is a useful initial step for other assembly pipelines.

21 This mechanism represents the initial step for the activation of innate immune respons

22 Molecular recognition is an important initial step for the biomolecular interactions and their

23 d represent the successful completion of the initial step for the preclinical development of 12/15LO

24 The work represents an important initial step for understanding the evolutionary history

25 Overall, the results establish the initial steps for how photoexcited CdS delivers electron

26 We describe initial steps for interrogating whole-genome sequence da

27 NAs (lncRNAs) in erythropoiesis.1 This is an initial step forward in our understanding of the many ro

28 Based on these initial steps, further progress in probe chemistry and t

29 Bypassing or altering this initial step has significant consequences for infection.

30 Initial steps have been taken to understand such issues

31 Here, we focus on the initial step in a membrane protein's life cycle: express

32 a 1,3 dipolar cyclo-addition reaction as the initial step in a novel type of enzymatic reaction.

33 This paper is intended to serve as an initial step in a public-private collaborative developme

34 tric oxide synthase (eNOS) uncoupling, is an initial step in atherosclerosis.

35 ype IV pili facilitate surface adhesion, the initial step in biofilm formation.

36 The initial step in cellular Cu handling is its transport ac

37 g a transcriptional network can be a helpful initial step in characterizing the different phenotypes

38 faces is generally thought to constitute the initial step in colonization, requiring adherence factor

39 This review focuses on the initial step in Cu homeostasis, the properties of the ma

40 iated at the epigenetic level may provide an initial step in delivering an appropriate response to en

41 As an initial step in designing a simplified bryostatin hybrid

42 ng the expression patterns of snoRNAs is the initial step in determining their functional significanc

43 The initial step in development of this histologically defin

44 Damage recognition is a key initial step in DNA repair.

45 hizont development, our findings identify an initial step in egress and show that host cell cytoskele

46 As an initial step in establishing the direction of causation

47 The initial step in eukaryotic DNA replication is the assemb

48 This study represents the initial step in exposing that DNA methylation directed b

49 study implicates accumulation of IMCs as an initial step in facilitation of tumor formation, followe

50 The initial step in FAK activation is autophosphorylation of

51 ach encoded by a separate gene, catalyze the initial step in glycerolipid synthesis; in liver, the ma

52 r the processivity of deep end-resection-the initial step in HRR.

53 lls on antigen presenting cells is a crucial initial step in immune response.

54 The initial step in initiation of eukaryotic DNA replication

55 droxylases (JBP1 and JBP2) that catalyze the initial step in J synthesis.

56 The initial step in mobilization is the derepression of the

57 face located and thus likely involved in the initial step in mucin breakdown.

58 As an initial step in our efforts to unify the expression of p

59 membrane (PM) depolarization functions as an initial step in plant defense signaling pathways.

60 impact mitochondrial function represents an initial step in predicting exposure-related toxicity and

61 These results can be considered as an initial step in predicting tumor response to nCRT in loc

62 Piezo1 in the pancreatic acinar cell is the initial step in pressure-induced pancreatitis, activatio

63 The Ku heterodimer serves in the initial step in repairing DNA double-strand breaks by th

64 steoblasts to sites of bone resorption as an initial step in replacing lost bone.

65 ndensation of serine with palmitoyl-CoA, the initial step in sphingolipid biogenesis.

66 The initial step in stereoscopic 3D vision is generally thou

67 o the mitochondria, which is the site of the initial step in steroidogenesis.

68 t it can act as a proton acceptor during the initial step in substrate proteolysis.

69 These findings demonstrate that the initial step in synapse disassembly involves postsynapti

70 However, the initial step in synthesis of these FA-VOCs has not been

71 chanisms by which the C2 domain controls the initial step in the activation of PKC.

72 ), an alpha2beta2gamma2hexamer, mediates the initial step in the addition of the mannose 6-phosphate

73 Reverse transcription is an essential initial step in the analysis of RNA for most PCR-based a

74 an uracil-DNA glycosylase (hUNG) perform the initial step in the base excision repair (BER) pathway.

75 Oxygenation of aromatic rings is a frequent initial step in the biodegradation of persistent contami

76 This is the initial step in the biosynthesis of the plant growth hor

77 as first proposed over 50 years ago that the initial step in the catalytic cycle is facilitated by a

78 ivision, termed heterogonesis, as the likely initial step in the causation of sesquizygosis.

79 We hypothesized that MIF triggers an initial step in the chemotaxis of IFN-gamma-producing ce

80 The initial step in the degradation of pentachlorophenol by

81 ase, encoded by the gene speG, catalyzes the initial step in the degradation of polyamines and is a c

82 The initial step in the demethylation process can be deamina

83 Nuclei detection is often a critical initial step in the development of computer aided diagno

84 n of mu opioid receptors is thought to be an initial step in the development of tolerance to opioids.

85 f ataxia-telangiectasia mutated (ATM) is the initial step in the DNA damage response and subsequent c

86 nsing of cytosolic nucleotides is a critical initial step in the elaboration of type I IFN.

87 the electrode surface, which is a necessary initial step in the electrocatalytic oxidation of CO on

88 extensive group-level adaptation during the initial step in the evolution of multicellularity.

89 e (LOX) precursor, the enzyme catalyzing the initial step in the formation of covalent collagen cross

90 2beta2gamma2 heterohexamer that mediates the initial step in the formation of the mannose 6-phosphate

91 ion of the maternal decidua appears to be an initial step in the maternal component of the disease as

92 clooxygenases, COX-1 and COX-2, catalyze the initial step in the metabolism of arachidonic acid to pr

93 The initial step in the metabolism of intracellular FA is th

94 a to dental implant surfaces is the critical initial step in the process of biofilm colonization; how

95 e produced was used to remove arsenic as the initial step in the process, and other chalcophilic meta

96 uity and the formation of progenitors as the initial step in the production of differentiated cells.

97 Evidence suggests that AAH represents an initial step in the progression to adenocarcinoma in sit

98 The single-electron transfer proposed as an initial step in the reaction of these hexamers with cert

99 osition suitable for ligation, revealing the initial step in the repair of double-strand DNA breaks.

100 m binding site Na2 had been identified as an initial step in the transport cycle which prepares the t

101 Although binding is the obligate initial step in the transport cycle, there is no empiric

102 The initial step in their synthesis is the activation of fat

103 hosphoribosyltransferase (UPP) catalyzes the initial step in this pathway and is required for the est

104 An initial step in this process is the loss of glandular st

105 The initial step in this technique involves cell disruption

106 retinoschisin deficiency could represent an initial step in XLRS pathogenesis.

107 anization is essential for understanding the initial steps in cell signaling and trafficking mechanis

108 sorbed species on electrode surfaces, and of initial steps in electrochemical phase formation process

109 As the initial steps in FVIII inhibitor development remain inco

110 ons of biological hypotheses surrounding the initial steps in GPVI-stimulated signal transduction.

111 netic effects which are most critical at the initial steps in infection.

112 al brain imaging in humans, this study takes initial steps in linking intrinsic measures of neuromodu

113 ortant roles in carcinogenesis and influence initial steps in neoplastic transformation by altering g

114 While the initial steps in Pfr signaling are unclear, an early eve

115 The initial steps in photosystem II (PSII) assembly are thou

116 Initial steps in protein synthesis are highly regulated

117 ons in expression relevant to the biology of initial steps in SARS-CoV-2 infection.

118 This platform exploits the fact that the initial steps in the biosynthesis of most bacterial glyc

119 An improved understanding of the initial steps in the development of RA would provide ins

120 in the triggering of bud outgrowth and that initial steps in the light signaling pathway involve cyt

121 te invasive behaviors that may contribute to initial steps in the metastatic cascade.

122 The initial steps in the micromolar concentration range foll

123 The initial steps in this process can be traced back to the

124 The initial steps in this protocol involve optimization of c

125 gimens, a more complete understanding of the initial steps in viral infection is necessary.

126 As an initial step, in this trial we assessed the effect of an

127 s thought to occur at the cell surface, with initial steps including proprotein processing, multimeri

128 study of monolignol biosynthetic genes as an initial step into the characterization of lignin metabol

129 required to inhibit ATM activation, the key initial step involved in the activation of a DNA-damage

130 The initial step involves adenylation of the enzyme by ATP,

131 The initial step is often the photoisomerization of a conjug

132 Diagnostically, the initial step is to differentiate hypotonic from nonhypot

133 cells and mechanistic information about the initial steps leading to the characteristic undulations

134 The initial step modified postembryonic development, resulti

135 tumor development have been discovered, the initial steps mutant cells take to escape tissue integri

136 that the detection pathway proceeds via the initial step of a five-membered ring formation upon atta

137 hydrophobic bacterium, S. wittichii RW1, the initial step of adhesion and maturation of bacteria-subs

138 The initial step of assembly-binding of X-targeting factors

139 -selective CRISPR array expansion during the initial step of bacterial adaptive immunity.

140 nonheme iron dioxygenases is frequently the initial step of biodegradation, O2 activation kinetics m

141 methods to prevent microbial adhesion as the initial step of biofilm formation.

142 The initial step of bone digestion is the adhesion of osteoc

143 omocoupling with 1a and 1b revealed that the initial step of CO binding and scission involved CO acti

144 In the initial step of colonization, FimH, a lectin located at

145 hat the V1/V2 domain plays a key role in the initial step of development of drug resistance.IMPORTANC

146 the following four proteins involved in the initial step of Fe-S cluster synthesis: FXN(42-210) (iro

147 myophosphorylase, the enzyme catalyzing the initial step of glycogen breakdown.

148 e entrance are conceivably essential for the initial step of H(+)-PPase proton translocation.

149 (Hb) and muscle components of fish may be an initial step of Hb-mediated lipid oxidation.

150 An initial step of image unmixing provides a set of pure di

151 Phospholipase C (Plc1p) is required for the initial step of inositol polyphosphate (InsP) synthesis,

152 Our findings are relevant to the initial step of ISWI binding to the nucleosome and provi

153 The initial step of metastasis is the local invasion of tumo

154 peutics for suppressing cancer invasion, the initial step of metastasis.

155 and MMP-9 act synergistically mainly at the initial step of neutrophil recruitment into the peritone

156 nt to chitin surfaces not only serves as the initial step of nutrient recruitment but is also a cruci

157 We used an in vitro assay that models the initial step of ovarian cancer metastasis, clearance of

158 Whereas the initial step of parenchymal cell proliferation was not a

159 The initial step of photocatalytic water oxidation reaction

160 steps of autophagy targeting, including the initial step of polyubiquitin-coat formation.

161 e-->CaI and activation thermodynamics of the initial step of proton reduction in CaI.

162 lmitoyltransferase, an enzyme catalyzing the initial step of sphingolipid biosynthesis.

163 The initial step of sporulation is asymmetric cell division,

164 We provide evidence for an initial step of TDP-43 self-assembly into intermediate o

165 ein (APP) by the beta-secretase BACE1 is the initial step of the amyloidogenic pathway to generate am

166 ells is primarily achieved by modulating the initial step of the base excision repair process.

167 ferases (NDSTs), the enzymes involved in the initial step of the biosynthetic pathway.

168 tional approaches were combined to study the initial step of the catalytic cycle.

169 In mammalian mitochondria, the initial step of the Fe-S cluster assembly process is ass

170 oxia (SAH) mouse model of DWMI activates the initial step of the ISR.

171 The initial step of the method is to liberate chemically and

172 ed by NiSOD, we computationally explored the initial step of the O2(-) reduction mechanism catalyzed

173 An initial step of the pathogenesis is an epithelial-mesenc

174 udies identify a key role for Asp-128 in the initial step of the phosphobase methylation pathway in P

175 All previous work on the initial step of the targeting reaction, when SRP binds t

176 g of two pyrrole molecues is found to be the initial step of this reaction.

177 omplex only on precleaved ends mimicking the initial step of transposition.

178 The initial step of violacein biosynthesis is the oxidative

179 chment of the virus to the cell surface, the initial step of virus entry, raises questions concerning

180 The genetic changes underlying the initial steps of animal domestication are still poorly u

181 autophagic effectors, like WIPI2, during the initial steps of autophagosome biogenesis and thereby re

182 NA glycosylases are enzymes that perform the initial steps of base excision repair, the principal rep

183 the influence of histone acetylation on the initial steps of BER, we assembled nucleosome arrays con

184 domain play distinct roles in regulating the initial steps of BER.

185 The initial steps of BIR occur normally in Pif1-deficient ce

186 podia function in SCC cells, controlling the initial steps of cancer cell invasion.

187 this by an improved characterization of the initial steps of CaP precipitation, permitting detection

188 ronmental responsiveness by representing the initial steps of cell signaling pathways.

189 new structural and mechanistic insight into initial steps of cell-driven FN fibrillogenesis.

190 f the mother centriole are essential for the initial steps of ciliogenesis in G1/G0 phase of the cell

191 by obtaining a detailed understanding of the initial steps of CO2 electroreduction on copper surfaces

192 ANKRD26 and detail, in high resolution, the initial steps of distal appendage assembly.

193 hat hormones likely play a minor role in the initial steps of early embryo development in maize.

194 The initial steps of gametocytogenesis remain largely unchar

195 BRD4 is a kinase involved in numerous initial steps of gene induction.

196 multi-protein complex, that facilitates the initial steps of gene transcription.

197 rd UV-damaged DNA, and it is involved in the initial steps of global genome nucleotide excision repai

198 ucosidase inhibitors, can interfere with the initial steps of glycan processing on proteins and inhib

199 f the EEI, we report here the details of the initial steps of H(2)O adsorption and complex formation

200 nt parasites lacking enzymes involved in the initial steps of Hb proteolysis.

201 The initial steps of HIV replication in host cells prime the

202 hogens, bind cell-surface glycans during the initial steps of infection.

203 that the events we report here represent the initial steps of insertion and assembly of these translo

204 ts myristoylation play a crucial role in the initial steps of invasion, likely during the interaction

205 response to fatty acids to characterize the initial steps of LD formation occurring in lipid-starved

206 hybridization analyses, we investigated the initial steps of left-right axis establishment in embryo

207 -binding adhesion molecules that mediate the initial steps of leukocyte recognition of endothelium.

208 of vitamin C together with indicators of the initial steps of Maillard reaction (2-furoylmethyl amino

209 ockdown cells had an unexpected advantage at initial steps of metastatic seeding, suggesting that Rab

210 induced the expression of genes involved in initial steps of mitochondrial steroidogenesis, suggesti

211 igher formation of furosine, as indicator of initial steps of MR, was observed together with more adv

212 se C2C12 myocytes, MYF5 is implicated in the initial steps of myoblast differentiation into myotubes.

213 reveal a detailed nanoscopic picture of the initial steps of nonphotochemical quenching.

214 microscopy, to enable in situ imaging of the initial steps of nucleation at the atomic scale.

215 d its alkyl substituents are often competing initial steps of organic pollutant transformation.

216 helial cells promote colonization during the initial steps of OvCa metastasis and suggest that mesoth

217 s of esterified linoleate proceed beyond the initial steps of oxidation and epoxyalcohol synthesis ca

218 hanolamine kinase (CEK) family catalyzes the initial steps of phospholipid biosynthesis.

219 e first time-domain theoretical study of the initial steps of photocatalytic water splitting on a GaN

220 plast thylakoid membrane is the site for the initial steps of photosynthesis that convert solar energ

221 s particle, variation in the kinetics of the initial steps of replication contributed significantly t

222 lth of the parasite protein machinery at the initial steps of ribosome biogenesis and conveys that in

223 quid phase separation (LLPS) facilitates the initial steps of ribosome biogenesis and other functions

224 Although the initial steps of rRNA processing in Escherichia coli (E.

225 coat protein complex II (COPII) mediates the initial steps of secretory protein trafficking by assemb

226 ovide a useful tool for future assessment of initial steps of sensory processing in S1.

227 ur results reveal unexpected features of the initial steps of sexual development and extend the curre

228 ol transport and metabolism machinery in the initial steps of steroid and/or oxysterol biosynthesis p

229 a(2+) binding and refine the currently known initial steps of STIM1 activation on a molecular level.

230 Shot is enriched in cells undergoing the initial steps of subcellular branching as a direct respo

231 observations provide an understanding of the initial steps of tau aggregation through interaction wit

232 e hydrogen abstraction, thereby refining the initial steps of the carbide insertion pathway.

233 he enzyme, which will help to understand the initial steps of the catalytic mechanism.

234 nal neural networks to solve problems in the initial steps of the common pipeline for data analysis i

235 ings highlight a new mechanism in one of the initial steps of the dentin-pulp regeneration process, l

236 harmonic fluctuations can be considered the initial steps of the DNA melting pathway.

237 to DNA provides mechanistic insight into the initial steps of the establishment of sister chromatid c

238 synthetic fusogens have only replicated the initial steps of the fusion cascade, we use molecular si

239 We observe that although in the initial steps of the packaging reaction, the torsional s

240 ttenuation of its kinase activity during the initial steps of the repair process is essential to effi

241 tes (dark, batho, BSI, lumi) involved in the initial steps of the rhodopsin photoactivation mechanism

242 Initial steps of transmission, including cell attachment

243 the foldamer (tau = 150 ps), indicating the initial steps of unfolding of the helical conformation,

244 le for facultative anaerobic bacteria in the initial steps of unsaturated LCFA biodegradation.

245 As the initial steps of unsaturated LCFA degradation proceed un

246 egraded by aerobic microorganisms, where the initial steps of various biodegradation pathways include

247 The initial steps of viral capsid self-assembly require weak

248 l nasal turbinate organ culture to study the initial steps of viral infection and the consequent inna

249 ffect occurred early during infection at the initial steps of viral RNA replication.

250 lly, the nuclear RNA exosome coordinates the initial steps of viral transcription with RNAPII at host

251 ZGA) is thought to occur gradually, with the initial steps of zygote and embryo development being pri

252 n per reaction, but require 10,000 cells for initial steps or require a highly specialized microfluid

253 Our experiments suggest that, in EOPE, the initial step precipitating disease is a reduced capacity

254 very different from that of NtQ42P10, as the initial steps require a monomer to 7-mer transition stag

255 Identifying orthologous genes is an initial step required for phylogenetics, and it is also

256 Here we focus on the initial steps restoring heterochromatic modifications in

257 res, dendrimers are ideally suited for these initial steps, since they consist of arrays of chromopho

258 lly observed isotope pattern requires, as an initial step, the calculation of the theoretical isotope

259 e time-evolution of excitons requires, as an initial step, the calculation of their spectra, which ha

260 ent phosphorylation of Ser65 is an important initial step, the molecular mechanisms underlying the ac

261 An initial step to capture the fingerprint of the core netw

262 This work represents the initial step to expose the role of epigenetic process, i

263 As an initial step to near real-time clinical learning during

264 The initial step to transformation, namely the uptake of DNA

265 cal blow against wild Cucurbita, and we take initial steps to consider this hypothesis through cross-

266 he basis of individual patient needs are the initial steps to inform the integration.

267 These findings provide the initial steps to understand the resistance mechanisms ag

268 yoxal, and IEPOX to partition to ALW, as the initial step toward aqSOA formation.

269 As an initial step toward assessing the cis-regulatory activit

270 These results constitute an initial step toward detailed molecular theory of additio

271 As an initial step toward development of ketone therapies, we

272 These results represent an initial step toward generating a platform to evaluate B

273 As an initial step toward identifying novel biased KOR agonist

274 d risk factors for incarceration provides an initial step toward mitigating the excess morbidity and

275 requires external validation but provides an initial step toward the development of the specific VTE

276 review its surgical treatment as a potential initial step toward the establishment of a definition of

277 The results of this study provide an initial step toward understanding the environmental beha

278 The initial step toward understanding the environmental impa

279 This work serves as an initial step toward using photoexcited QDs to strongly s

280 and ischemic disease models is an important initial step toward using them for heart disease treatme

281 We describe initial steps toward a minimum-sized, soluble model syst

282 d of nucleus taenia/TnA), AMD, AD, and AI as initial steps toward a universal arcopallial nomenclatur

283 In initial steps toward achieving these goals, we construct

284 roliferation and survival that may represent initial steps toward NB development.

285 The initial steps toward optical detection and spectroscopy

286 Therefore, in an initial step towards an improved understanding of MMP fu

287 rization of the complete human phallus is an initial step towards developing a tissue engineered huma

288 This work represents a significant initial step towards enhancing photosynthesis in higher

289 ncAAs at the first and second positions, an initial step towards producing completely unnatural poly

290 n offshore waters and represent an important initial step towards quantitatively evaluating Atlantic

291 re with a spatially dependent bandgap, as an initial step towards the creation of diverse lateral jun

292 to understand it, these results represent an initial step towards the deeper understanding of the com

293 As an initial step towards this goal, isolated nuclear spins a

294 /alphavbeta3 integrin binding, we provide an initial step towards understanding how the neuron-astroc

295 As initial steps towards establishing a human cellular and

296 ional quantum dynamical studies representing initial steps towards obtaining CO-H(2) rovibrational qu

297 /or in the Met chain elongation pathway, the initial steps towards the biosynthesis of Met-derived gl

298 These results provide initial steps towards the development of a quantitative

299 often considered to be a prerequisite to the initial step (transimination) of the enzyme-catalyzed re

300 The initial step was ganglioside dependent, while the subseq