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1 ch first-time treatment with vedolizumab was initiated.
2 l, after which sensorimotor beta-bursting re-initiates.
3 enrollment when a formal LVAD evaluation was initiated, 162 patient-caregiver dyads completed assessm
4 e show that SSBs are first sensed by APE1 to initiate 3'-5' SSB end resection, followed by APE2 recru
5 lithostatic load, create under-pressure and initiate a caldera collapse, despite only modest precurs
6 in Abeta precipitate the disease process and initiate a deleterious cascade involving tau pathology a
8 cardiac antigen to T cells, and potentially initiate a persistent autoimmune response against the he
9 the form of elevated extracellular K(+) and initiate a retrograde, propagating, hyperpolarizing sign
10 bilizes the half-life of p53 and uses p53 to initiate a slow-cycling state following stress (DNA dama
14 e preparedness for future pandemics, we have initiated a network of nine European-funded Cooperation
15 ed virus particles suggests receptor binding initiates a cascade of conformational changes that produ
16 Our data support a model in which ANKRD26 initiates a centriole-derived signal to limit cell proli
17 k hypothesis suggests that early-life stress initiates a positive feedback loop between peripheral in
18 ingle electron transfer (SET) to this system initiates a rearrangement, and the catalytic cycle is co
20 al irritants, and damaged cells subsequently initiating a well-orchestrated adaptive immune response.
21 tivity, high levels of ki-67 and high tumour-initiating abilities are characteristic of invasive amoe
22 nd serum potassium testing within 30 days of initiating ACE (angiotensin-converting enzyme) inhibitor
24 ssociation between vitamin D supplementation initiated after breast cancer diagnosis and all-cause mo
25 ce (HIVDR), but few studies include children initiating age-appropriate WHO-recommended first-line re
26 e to distinct biological functions: free IgE initiated allergic inflammation through FcepsilonRI on a
27 icrobial ligands and various noxious cues by initiating an inflammatory response aimed at eliminating
29 titial and perivascular adipose tissue cells initiate and regulate important vascular functions in di
30 r all complexes, suggesting their ability to initiate and terminate a C(sp(3))-H halogenation sequenc
32 osed of Rca-alpha only are less effective in initiating and sustaining the activation of Rubisco than
33 tions regarding tumor innervation, how it is initiated, and how it molecularly contributes to disease
34 the threshold for SFK activity necessary to initiate antigen receptor signaling in both T and B cell
35 ood pDCs in 29 HIV-infected participants who initiated antiretroviral therapy during acute infection
36 synthesize nucleotide second messengers and initiate antiviral responses in bacterial and animal cel
38 antibody response to a parasite antigen that initiates apoptosis-like cell death of parasites, adding
39 t proviruses can be detected in children who initiate ART after 2.3 months of age and are probably, a
40 ntact sequences were from three children who initiated ART after 2.3 months of age, one of whom had t
42 e living with HIV aged 15 years or older who initiated ART at a programme site were eligible for anal
43 lity rate among the 835 participants who had initiated ART was 1.9 per 100 person-years (95% CI 0.9-3
47 factors related to initiating (including re-initiating) ART in the hospital and its association with
51 omal marker Rab5, and new microtubule growth initiated at puncta marked with fz, dsh, Axin, and Rab5.
52 in show that pit formation is preferentially initiated at the interface between adventitious C nanopa
57 lls (DCs) that, during hypercholesterolemia, initiate atherosclerosis by being the first to accumulat
59 ery and, for maximal effectiveness, could be initiated before administration of adjuvant therapies.
60 sening heart failure, sotagliflozin therapy, initiated before or shortly after discharge, resulted in
62 s induced by meiotic recombination, which is initiated between homologs at >200 sites originating fro
64 f the subject, and the age by which subjects initiated brushing habits, and the types of actions post
67 In cardiac myocytes, action potentials are initiated by an influx of sodium (Na(+)) ions via voltag
68 athway is required for the signaling cascade initiated by BDNF and its receptors at the plasma membra
70 ation of polychlorinated biphenyls (PCBs) is initiated by cytochrome P450 (CYP) enzymes and includes
71 on of the predominant {1 0 -1 2} twinning is initiated by disconnections on the Prismatic Basal inter
72 m that a superoxide-mediated chain reaction, initiated by electrocatalytic oxygen reduction on the ca
74 hat aggressive encounters between groups are initiated by females, who gain fitness benefits from mat
76 ions because the deprotection process can be initiated by illumination with light without the necessi
79 sanoid production in most mammalian cells is initiated by phospholipase A(2)-mediated release of arac
80 thway to these cleavage products is complex, initiated by regioselective oxygen radical addition to t
81 patterns are best modeled as mtDNA deletions initiated by replication fork stalling during strand dis
82 immunity is orchestrated by signaling events initiated by TCR recognition of peptide Ag in concert wi
84 he endoderm GRN in Caenorhabditis elegans is initiated by the maternally supplied SKN-1/Nrf2 bZIP tra
86 Th) cell-dependent lung eosinophilia that is initiated by the rapid response of bronchiolar club cell
87 r new annotation tracks, heavy-duty analyses initiated by the user from within the browser, and other
92 n-regulation of vacuole membrane proteins is initiated by ubiquitination, which is accomplished by th
93 otoinduced single electron transfer has been initiated by utilizing the visible-light absorptivity of
94 atory syndrome coronavirus 2 (SARS-CoV-2) is initiated by virus binding to the ACE2 cell-surface rece
95 reast cancer cells can increase their cancer initiating capacity through activation of a type I inter
96 sequence of 3-hydroxyazetidines via a Ritter initiated cascade provides highly substituted 2-oxazolin
103 We report that radiation induces a glioma-initiating cell phenotype, and we have identified triflu
104 ormal myeloid progenitors (AMPs), a leukemia-initiating cell population induced by Cbfb-MYH11 in the
105 for distinct subsets of chemoresistant tumor-initiating cell populations in diverse human malignancie
106 cancer stem cell markers, inhibit the tumor-initiating cell's neurosphere-forming capacity, and migr
107 reversibly between slow-proliferating tumor-initiating cells (TIC) and their differentiated, faster-
109 EFTY1-BMPR2 interaction is specific to tumor-initiating cells in triple-negative breast cancer xenogr
111 stomas we tested including glioblastoma stem/initiating cells, but hardly detectable in non-neoplasti
112 udy demonstrates that fluid flow application initiates changes in intestinal epithelial cell characte
119 ol II to successfully escape the promoter as initiating complexes transition into elongation complexe
120 ic cannabinoid receptor agonists (SCRAs) has initiated considerable interest in the development of so
121 sting ones, altered compartmentalization and initiated contacts reflecting chromatin loop extrusion.
122 e that healthcare providers are reluctant to initiate conversations around sexual health or offer app
124 reatment of the reaction mixture with a base initiated deep structural transformation of primary prod
125 decision in preterm and early term provider-initiated deliveries, and to prevent perinatal adverse o
127 a common signal with specific machinery that initiates discrete signaling cascades to produce a local
128 ence of a pathogen, activated CD4(+) T cells initiate distinct gene expression programs that produce
129 cleaved by the ribonuclease to specifically initiate DNA amplification and generate strong fluoresce
132 tein deposition onto BrM glycosaminoglycans, initiating downstream effects that contribute to RPE dys
135 ells recruited to the CNS during CD4+ T cell-initiated EAE engaged in determinant spreading and influ
137 demonstrating that surface-stimulated cells initiate early chromosome replication to the same extent
139 streptomycin or gentamicin is effective when initiated early in illness but can have serious side eff
141 ighlights, at a biochemical level, how tumor-initiating ETS translocations result in reprogramming of
144 in other populations, but they suggest that initiating FA supplementation >= 3 months prior to pregn
148 ment with ciprofloxacin and levofloxacin was initiated from 0 to up to 30 hours after fever onset.
149 ell-containing axillary meristems, which are initiated from a leaf axil meristematic cell population
150 retroviral elements and chimeric transcripts initiated from long terminal repeats during zygotic geno
151 ion, and molecular dynamics (MD) simulations initiated from Rosetta predictions to gain insights on t
154 alpha-synuclein or DISC1 that may be able to initiate further detrimental downstream events and shoul
157 rease), and intravenous fluid administration initiated >=4 days following diarrhea onset (2.50 [1.14-
158 ides extreme reward with no nutritive value, initiating high selectivity and prolonged cravings for d
161 ated billions of dollars and scientists have initiated hundreds of clinical trials in an expedited ef
165 pport the idea that co-obligate associations initiate in a predictable manner-through parallel evolut
169 ong a reproducible developmental trajectory: initiated in basal cells exhibiting an epithelial-to-mes
170 dy's responsive parenting (RP) intervention, initiated in early infancy, prevented the use of nonresp
171 lsartan in HFpEF appear to be amplified when initiated in the high-risk window after hospitalization
172 clusion therapy to treat amblyopia should be initiated in these patients to ensure that they reach th
173 s track where a porosity-generating reaction initiates in shale in three boreholes across the landsca
174 condary analysis examined factors related to initiating (including re-initiating) ART in the hospital
175 member of the NOD-like receptor family that initiates inflammatory signaling in response to the bact
178 CoV-2 virus and subsequent COVID-19 pandemic initiated intense research into the mechanisms of action
179 lites produced by the host and microbiota to initiate intestinal colonization of avian and animal hos
181 hese mechanisms and determining how they are initiated is fundamental to further our understanding of
183 tion, very low certainty); 3) we suggest not initiating long-term NIV during an admission for acute-o
185 atients (292 adolescents and 553 adults) who initiated lumacaftor-ivacaftor, 18.2% (154 patients) dis
189 o retinoic acid-inducible gene I (RIG-I) and initiate mitochondrial antiviral signaling (MAVS) protei
190 main activates the IRE1alpha nuclease, which initiates mRNA splicing of X-box binding protein-1 (XBP1
191 ion (ERADICATE-AF) trial was an investigator-initiated, multicenter, single-blind, randomized clinica
192 edisposition affects the penetrance of tumor-initiating mutations, such as APC mutations that stabili
193 sistent AF (VENUS) trial was an investigator-initiated, National Institutes of Health-funded, randomi
194 es to "fill the gap" of absent family and by initiating new and established ways to connect patients
195 with chronic stable hypercapnic COPD who are initiating NIV (conditional recommendation, very low cer
196 ed that purified bacterial collagenase would initiate nociceptive cascades in the joint by degrading
199 246 children living with HIV (HIV+) who were initiated on ART before 3 years of age in a prior clinic
201 different forms of aneuploidy represent the initiating oncogenic lesion in patients with B cell acut
203 processes from denervated NMJs and failed to initiate or guide nerve terminal sprouts at disease-vuln
204 ients whose immune response had not yet been initiated or who had a high viral load at baseline.
207 Additionally, we demonstrate that PDGFRbeta-initiated phosphorylation of PRAS40 is required for TGFb
208 k of piRNA-piRNA precursor interactions that initiate piRNA production from a second piRNA locus on c
209 by penicillin-binding protein 3 (PBP3/FtsI) initiate polarized division, but the process arrests at
210 illin-binding protein 2 (PBP2) are unable to initiate polarized division, while cells treated with in
211 atalyst, protic chain transfer agents (CTAs) initiate polymerization and facilitate rapid proton tran
212 us with insights into how these networks are initiated, positioned and regulated, and how they act vi
213 NA-Seq), this low amount of IgHC sufficed to initiate PreB cell markers normally associated with PreB
214 ent, health centers tracked whether patients initiated prenatal care in their first trimester of preg
216 440 person-years of follow-up, 44% of YBMSM initiated PrEP through the study after a median of 122 d
217 ed a successful outcome: first, a person who initiates PrEP must not seroconvert; second, there shoul
220 eviously shown that oral azithromycin (AZM), initiated prior to MI, reduces inflammation and its nega
221 mes are specifically recognised by ZNF598 to initiate protein and mRNA quality control pathways.
223 ion within 90 days and 19.6% of patients who initiated pulmonary rehabilitation after 90 days or not
224 of discharge, including 7.3% of patients who initiated pulmonary rehabilitation within 90 days and 19
226 ibuted, the double-strand breaks (DSBs) that initiate recombination are not located arbitrarily(2).
227 any vertebrates, double-strand breaks (DSBs) initiate recombination within hotspots where PRDM9 binds
230 modeling reveals that pore pressure changes initiate seismicity on critically stressed faults and Co
232 development of oropharyngeal symptoms after initiating should alert the treating physician to the po
233 ditionally, our study positions mitochondria-initiated signaling as key element of the VSMC different
234 tested the hypothesis that endothelial cell-initiated signaling is necessary to maintain self-renewa
242 the cost-effectiveness of four primary care initiated strategies: (1) routine liver function tests w
243 that primase can use metabolic cofactors as initiating substrates, instead of its canonical substrat
244 volutionary similarity between the autophagy-initiating TBK1 kinase and the ULK1 kinase complex.
246 d has grown, several companies have recently initiated testing of direct NLRP3 inhibitors in the clin
247 ENDATION 2: ACP suggests that clinicians not initiate testosterone treatment in men with age-related
248 ar rather than transdermal formulations when initiating testosterone treatment to improve sexual func
249 ified kallikrein activated FIX in buffer and initiated TG in normal pooled plasma, as well as FXII- o
252 res reported in this study may contribute to initiate the design for possible transmission-blocking a
253 the N-terminus of Abeta as a region that may initiate the formation of damaging oligomeric species.
254 indicate that Hoxa13 acts hierarchically to initiate the formation of digit 1 by reducing Gli3 trans
256 g a previous bout of torpor is sufficient to initiate the key features of torpor, even in mice that a
258 nmental or developmental cues, sigma factors initiate the transcription of necessary genes responsibl
260 mutant induced oncogenic PI3K signalling and initiated the transformation of premalignant B cells.
264 rugs and acetylenedicarboxylate derivatives, initiating the downstream release of the small molecule
265 stone modifiers to engage chromatin, thereby initiating the formation of an activating or repressive
266 ctive serotonin reuptake inhibitors (SSRIs), initiate their drug actions by rapid elevation of seroto
268 North American AIDS Cohort Collaboration who initiated their first ART regimen, containing either InS
269 s to exclude HT based on SUVmax alone before initiating therapy in patients with high tumor burden FL
270 ness may benefit from further work up before initiating therapy, whereas patients with septic shock w
272 eviously characterized splicing kinase SRPK1 initiates this life-beginning event by catalyzing site-s
273 ine responses promote parasitic immunity and initiate tissue repair; however, they can also result in
274 en VA >= 0.3 logMAR bilaterally; secondary = initiated to correct residual IOD once VA improved to <=
276 el feature encoding and learning scheme were initiated to produce and rank physicochemical property-r
277 , 12-subunit enzyme, it lacks the ability to initiate transcription and cannot consistently transcrib
281 gle amino acid is essential for engaging and initiating transport of multiple drugs and xenobiotics.
282 n has the potential for physicians to timely initiate treatment with reduced mortality and costs.
283 TB developed in 49 (9.8%) of 446 who did not initiate treatment, 8 (1.8%) of 443 who received partial
285 apoptosis as well as altered distribution of initiated tumors in the lung, resulting from loss of p10
290 y the mammalian RAG1-RAG2 recombinase, which initiates V(D)J recombination, we find that the active s
291 dults with a comorbid psychiatric condition, initiating varenicline in adults even if they are unread
292 e tissue origin of the arrhythmic beats that initiate ventricular tachycardia, and regarding optimal
293 main of RNA polymerase II (RNAPII), which is initiated when RNAPII reaches the middle of RDH genes an
294 may preserve kidney function in CKD, even if initiated when serum bicarbonate concentration is normal
295 er primary or secondary occlusion (primary = initiated when VA >= 0.3 logMAR bilaterally; secondary =
296 ein biogenesis is essential in all cells and initiates when a nascent polypeptide emerges from the ri
297 ar low, and the number of antibacterial INDs initiated with the FDA from 2010-2019 was lower than any
298 interventions were evaluated, with treatment initiated within 2 hours of TBI: out-of-hospital tranexa
299 emcitabine-platinum combination chemotherapy initiated within 90 days after nephroureterectomy signif
300 Pioneer factors such as Zelda (Zld) help initiate zygotic transcription in Drosophila early embry