ライフサイエンスコーパス: inner

1 rmined the differential aging effects of the inner 6 layers of the macula in contrast to the minimum

2 s calculated using custom Matlab software in inner and outer annuli around the optic nerve region in

3 tained fewer microplastics than samples from inner and outer bends.

4 nct sheath proteins localize to the filament inner and outer curvatures to define the supercoiling ge

5 We find that high occupancy of nodes in the inner and outer k-shells and low occupancy in the middle

6 lial cell types, endoderm and ectoderm, into inner and outer layers, respectively.

7 ha3, and beta1 were more concentrated in the inner and outer layers.

8 s of interacting protein rings, spanning the inner and outer membranes to form the ~45-50-nm protein

9 is a double membrane barrier composed of the inner and outer nuclear membranes as well as a ~40-nm wi

10 rther, we tested direct interactions between inner and outer photoreceptors using selective recovery

11 littermate WT mice, hWtEPOR mice had thinner inner and outer plexiform layers and a greater number of

12 Fibrils in the inner and outer regions of the ZP are oriented perpendic

13 sociation with other specific changes in the inner and outer retinal layers.

14 The thickness values of both inner and outer rings of the Early Treatment Diabetic Re

15 psid, indicating that an optimal fit between inner and outer shells maintains capsid function.

16 and pixels each, with pitch of ~8 nm, on its inner and outer surfaces.

17 bers were measured at an optic disc centered inner and outer zone.

18 Hair cell counts (both inner and outer) as well as frequency maps of the BM wer

19 assuming a packed conformation, with ordered inner and peripheral rings, that prevents dimerization a

20 was thickest at the superior-inner, inferior-inner, and central macular regions (370-373 mum) and thi

21 r tolerance, and the effects of solvation on inner- and outer-sphere mechanisms.

22 re formed between the outer braided yarn and inner axial yarn, the 3DB-TENG is also endowed with high

23 The extracts were prepared from the inner bark and heartwood of samples harvested in the 201

24 Attention-based U-Net in extracting both the inner (blood flow) lumen and the wall structure of the a

25 s that connect the cristae membrane with the inner boundary membrane, thereby ensuring a contiguous i

26 rg1 and lamc3) was validated at the level of inner BRB cells.

27 oteins produced by the developing conceptus (inner cell mass and extraembryonic membranes).

28 esults show primarily active ERK in both the inner cell mass and trophectoderm cells due to fibroblas

29 the segregation of the trophectoderm and the inner cell mass influence lineage fate, via differential

30 d cells in the trophectoderm compared to the inner cell mass, although we do detect such enrichment i

31 nforcement by mechanical feedback within the inner cell walls, not the outer epidermal wall, in guidi

32 However, in inner cells of the placode, both Crumbs and Rok are isot

33 oxel-wise as a function of distance from the inner central canal CSF pool to the outer subpial surfac

34 bute to the organization and function of the inner centromere during mitosis.

35 hase separation (LLPS) and proposed that the inner centromere is a membraneless organelle scaffolded

36 PC) localizes to and is the key regulator of inner centromere organization and function during mitosi

37 riggers mobilization of Aurora B kinase from inner centromeres to kinetochore proximal centromeres an

38 ructure contains a magnesium engine core and inner chemoattractant and therapeutic layers.

39 y homologous to the translocons of outer and inner chloroplast membranes, respectively.

40 NO(2) exposure effects on asthma symptoms in inner-city children.

41 are for women at increased risk of PTB in an inner-city maternity service in London (UK), but there i

42 xamine the mechanisms by which a cargo-bound inner coat layer recruits and is organized by an outer s

43 coat protein, Sec31, drives binding with an inner coat layer via multiple distinct interfaces, inclu

44 Calretinin (CR) neurons in lamina II inner convey mechanical allodynia induced by inflammator

45 ronmental friendliness, and action driven by inner conviction; hierarchy privileges conformity, order

46 onductivity and relative permittivity of the inner core (composed of the cytoplasm, lipid droplets, a

47 Our results provide key constraints on inner core age that could be older than two billion-year

48 e transport properties of iron under Earth's inner core conditions are essential input for the geophy

49 re manufactured with or without a degradable inner core designed to modulate aqueous humor outflow to

50 e electronic stabilization together with the inner core geometric stability and the optimally stapled

51 The inner core has a monotwinned/stacking-faulted face-cente

52 The inner core is made of multiple connected DNA double heli

53 The monotwinned inner core structure of the ligand capped Au(191) nanomo

54 1- and 12-positions of the hetero[5]helicene inner core surface.

55 in a Keplerate cluster that was lined on the inner core with phosphate anions, {Mo(132)PO(4)}.

56 -weight keratin hydrogel was selected as the inner core.

57 holds for the both likely iron phases in the inner core.

58 calized electronic superatom spectrum of the inner core.

59 ed panel of oligosaccharides composed of the inner-core of the LOS of C. jejuni extended by various g

60 in compressibility due to ionization of the inner-core orbitals of carbon.

61 n cholesterol and sphingomyelin, whereas the inner, cytoplasmic leaf is rich in phosphatidylserine an

62 observations of ion transport across 1.1 nm inner diameter RNT porins (RNTPs) of various lengths in

63 MH basal diameter was 899.4 mum and the mean inner diameter was 516.1 mum.

64 e mechanoreceptive sensory hair cells in the inner ear are selectively vulnerable to numerous genetic

65 Structures in the inner ear can help determine the evolutionary relationsh

66 Mechano-sensory hair cells within the inner ear cochlea are essential for the detection of sou

67 ntial of ALD for the prevention/treatment of inner ear disorders such as age-related hearing loss.

68 out the otic placode lineage, comprising the inner ear epithelium and neurons.

69 ck is important for long-term maintenance of inner ear function.

70 the driving force for sound transduction by inner ear hair cells.

71 ed by the death of sensory hair cells of the inner ear is an unfortunate side effect for many patient

72 Each vestibular sensory epithelium in the inner ear is divided morphologically and physiologically

73 function of let-7 in HC differentiation and inner ear morphogenesis.

74 n partner-like 5 (Lhfpl5), and Transmembrane inner ear protein (Tmie).

75 her, conditional loss of the Yap gene in the inner ear results in the formation of significantly smal

76 y where the peripheral otolith organs in the inner ear sense both head tilts and translations.

77 In response to heat stress, inner ear tissue releases exosomes that carry HSP70 in a

78 field generated by the sensory cells of the inner ear to serve as a sound source microphone for full

79 In the inner ear, levels of HGF must be fine-tuned for normal h

80 ice limits CHD7 expression in the developing inner ear, retina and brain.

81 ts, such as the cochlear part of the osseous inner ear, that provides optimal contexts for DNA preser

82 In the inner ear, these acoustic receptors are primarily attach

83 large morphotype, including its endocast and inner ear, to reveal its morphology for the first time.

84 o ascribe resulting phenotypes solely to the inner ear.

85 exact location of cellular damage inside the inner ear.

86 osensitivity in the tmc1/2a/2b triple mutant inner ear.

87 -cell-autonomous protective signaling in the inner ear.

88 we microinjected ASO directly into the E12.5 inner ear.

89 elaborate, as they have outer-, middle-, and inner-ear components.

90 These new findings are inconsistent with the inner-ear compression mechanism that some have used to e

91 xperimental-modeling study suggests that (1) inner-ear fluid inertia is an important mechanism for BC

92 structural determinants of tip-link-mediated inner-ear sensory perception and elucidate protocadherin

93 The middle and the inner ears of WT and Nhe6 KO mice were not different mor

94 ructural and molecular changes in the middle/inner ears utilizing otoscopy, RNA sequencing (RNA-seq),

95 ust can postpone planetary water loss at the inner edge of the habitable zone, through a feedback inv

96 acitance that exists due to the considerable inner electric field force at the nanoscale.

97 In both varieties, from the surface to inner endosperms, protein and oil increased then decreas

98 ost of chloroplast PG assembly occurs at the inner envelope membrane, FAD4 was primarily associated w

99 esignated as the translocon at the outer and inner envelope membranes of chloroplast (TOC-TIC) comple

100 recently from bulky devices with an aqueous inner filling solution to planarizable solid-contact ele

101 uenched by the addition of quercetin through inner filter effect (IFE) mechanism.

102 Feature selection is applied in each inner fold and the consensus of top features across fold

103 fold based on features that give the maximum inner-fold accuracy.

104 use it does not construct classifiers in the inner folds.

105 From this state (inner gate open and outer gate closed), two additional s

106 ange in our dataset involves rotation of the inner-gate backbone along residues S168-G169-I170.

107 Mammalian cochlear inner hair cells (IHCs) are specialized sensory receptor

108 Inner hair cells (IHCs) are the primary receptors for he

109 Inner hair cells (IHCs) are the primary sensory receptor

110 cient mice, outer hair cells (OHCs), but not inner hair cells (IHCs), began to lose their third row o

111 f spiral ganglion neurons (SGNs) on cochlear inner hair cells (IHCs), resulting in loss of synapses,

112 natal day 7 (P7), before the primary sensory inner hair cells (IHCs), which become competent at about

113 onset of spontaneous correlated activity in inner hair cells and spiral ganglion neurons, which begi

114 Inner hair cells from TMIE mutant mice show altered post

115 We show that burst firing of mouse inner hair cells prior to hearing onset requires P2RY1 a

116 Solution effects on inner hair cells reduced auditory nerve compound action

117 sure and active outer hair cell force to the inner hair cells that synapse on afferent nerves.

118 Afferent synapses were lost from inner hair cells throughout the aged cochlea, together w

119 f pre- and post-synaptic markers on cochlear inner hair cells, in guinea pigs surviving from 1 day to

120 (+) efflux, and subsequent depolarization of inner hair cells.

121 , ectopic HCLCs emerged in regions medial to inner HCs as well as in the stria vascularis.

122 llular gating involves lysine protonation on inner helices and the formation of a protein seal betwee

123 Observations show that in the inner heliosphere, the electron temperature declines wit

124 Subjecting the inner hydrogel layer to Zn(2+)-ions and/or the outer hyd

125 and of [Formula: see text] exchanges in the inner hypoxic regions where tumor cells are known to acq

126 The choroid was thickest at the superior-inner, inferior-inner, and central macular regions (370-

127 lectrode surface repels salt anions from the inner layer and results in an inner SEI that is thin, de

128 that differential proteoglycan dynamics and inner layer buckling were positively selected during evo

129 Inner layer cells branch from transcriptionally uncommit

130 lithiated liquid metal (Li(x) LM(y) ) and an inner layer of Li metal, is developed, which posesses hi

131 rine (PS), a phospholipid constituent of the inner layer of the plasma membrane (PM).

132 st of a bilayer structure with the outer and inner layers derived from the {111} and {100} planes of

133 phosphatidylcholine, and cholesterol and the inner leaf of phosphatidylethanolamine, phosphatidylseri

134 lesterol and phosphatidylethanolamine in the inner leaf.

135 g helix (TM) and another that penetrates the inner leaflet (IM).

136 The first arises from the inner leaflet and is coordinated by hydrophobic residues

137 is asymmetry, the net-negative charge at the inner leaflet exceeds that at the outer leaflet.

138 nolamine (PE) are usually sequestered to the inner leaflet of the plasma membrane of the healthy euka

139 roviral Gag polyproteins are targeted to the inner leaflet of the plasma membrane through their N-ter

140 elp to explain the behavior of PIP(2) on the inner leaflet of the plasma membrane, where it is involv

141 an asymmetric lipid bilayer that consists of inner leaflet phospholipids and outer leaflet lipopolysa

142 utside/PC inside vesicles, the PC-containing inner leaflet tended to destabilize ordered domain forma

143 ded complex, including helix 8 burial in the inner leaflet, ordered lysine and arginine side chains i

144 a more compact E. coli MscL at the membrane inner-leaflet, as a consequence of a rotated TM2 helix.

145 owing to their propitious location above the inner limiting membrane (ILM), allowing direct visualiza

146 onsists of a tapered substrate with a hollow inner lumen for holding the imaging probe, and three opt

147 dispensable in unlocking and deciphering the inner mechanisms of real systems in diverse disciplines

148 kidneys and of dissected cortex, outer, and inner medulla, to represent the corticomedullary axis, w

149 tions along the nephron and in the outer and inner medulla.

150 ated activation of potential target genes in inner medullary collecting duct cells.

151 in which anterograde PL transport causes the inner membrane (IM) to shrink and eventually rupture; ch

152 ly if the function of the translocase of the inner membrane 23 is compromised such as in temperature-

153 ns, and nucleotides across the mitochondrial inner membrane and are crucial for many cellular process

154 ransporter LptB(2) FGC extracts LPS from the inner membrane and places it onto a periplasmic protein

155 LPS molecules are synthesized in the inner membrane and then transported to the cell surface

156 ds after their synthesis is completed at the inner membrane and transport them to the outer membrane.

157 An inner membrane assembly platform and a cytoplasmic motor

158 ne and active efflux via efflux pumps in the inner membrane creates a permeability barrier.

159 tudy thus reveals that the morphology of the inner membrane does not influence the subcompartmental p

160 lyze recently solved structures of bacterial inner membrane efflux pumps as to how they bind and tran

161 ing force for their translocation across the inner membrane is provided by the presequence translocas

162 main is positioned in close proximity to the inner membrane leaflet, enabling the reduction of membra

163 of the Fmr1(-/y) mouse have a mitochondrial inner membrane leak contributing to a "leak metabolism."

164 insertion into and translocation across the inner membrane of E. coli.

165 ated GTPase M (IRGM) in human locates at the inner membrane of mitochondria and is best known for its

166 s is counterbalanced by a high mitochondrial inner membrane potential, even under conditions of sever

167 ase and thereby maintains quality control of inner membrane preproteins sorting.

168 Here we characterize the inner membrane protein PbgA and report that its depletio

169 e mechanism is analogous to that used by the inner membrane protein TonB to dislodge the plug domains

170 How the inner membrane protein YejM with its periplasmic domain

171 ry focus on the assembly and function of the inner membrane pumps.

172 ds interface with the 24-fold symmetric SctD inner membrane ring (IR) via an adaptor protein (SctK).

173 mation of cristae creates more mitochondrial inner membrane surface area and thus more protonic capac

174 the proton motive force generated across the inner membrane with energy-dependent pyocin translocatio

175 pe, which comprises an outer membrane and an inner membrane, are an important and attractive system f

176 l for lateral sorting of preprotein into the inner membrane, as well as maintaining mitochondrial mor

177 ed a FUNDC1 interactome at the mitochondrial inner membrane, comprising the AAA+ protease, LonP1, and

178 sence of a reduced form of the translocon of inner membrane, they failed to identify any outer-membra

179 insertion into and translocation across the inner membrane, were unaffected.

180 ose synthase subunit G (BcsG) is a predicted inner membrane-localized metalloenzyme that has been pro

181 the proper architecture of the mitochondrial inner membrane.

182 dary membrane, thereby ensuring a contiguous inner membrane.

183 drive protons across the energy-transducing inner membrane.

184 g motif along the periplasmic leaflet of the inner membrane.

185 tes with the outer side of the mitochondrial inner membrane.

186 re, the proton-motive force (PMF) across the inner-membrane acts at distinct stages of protein secret

187 ntermediate filament cytoskeleton called the inner-membrane complex (IMC).

188 e describe a mechanism for how mitochondrial inner-membrane fusion is regulated by the ratio of two f

189 distinct mechanism related to mitochondrial inner-membrane hyperpolarization.

190 ransporters, and the structure of the entire inner-membrane MlaFEDB complex remains unknown.

191 r environmental signals to the cytoplasm via inner-membrane sigma regulators.

192 family, mediates fusion of the mitochondrial inner membranes, regulates cristae morphology, and maint

193 The inner microcapsule is separated from an outer aqueous co

194 contact sites was modulated by the outer and inner mitochondrial membrane channels, voltage-dependent

195 Cardiolipin is a phospholipid of the inner mitochondrial membrane essential for the function

196 In this study we report that MxB is an inner mitochondrial membrane GTPase that plays an import

197 multi-protein complex whose assembly in the inner mitochondrial membrane is facilitated by the scaff

198 activate a large conductance channel in the inner mitochondrial membrane known as the PTP (permeabil

199 nd extrusion by cation exchangers across the inner mitochondrial membrane may define the threshold; h

200 RP linked to Fragile-X syndrome elevates the inner mitochondrial membrane proton leak, leading to inc

201 and tightly controlled Ca(2+) channel of the inner mitochondrial membrane that regulates cellular met

202 ds cardiolipin on the concave surface of the inner mitochondrial membrane, before oxidizing the lipid

203 ific activation of signaling pathways in the inner mitochondrial membrane, thereby modulating its fun

204 rotein that we found was associated with the inner mitochondrial membrane.

205 cts with the phospholipid cardiolipin in the inner mitochondrial membrane.

206 en species by modulating the fluidity of the inner mitochondrial membrane.

207 )-regulatory mechanisms on both sides of the inner mitochondrial membrane.

208 of transfection, fibers were present in the inner molecular layer, but they progressively expanded i

209 agittarius A*, and stellar feedback from the inner molecular ring(1) expel matter and energy from the

210 l for global CO(2) reductions, while that of Inner Mongolia has adverse effects.

211 ation experiment in a temperate grassland in Inner Mongolia.

212 and bipolar cells was evident throughout the inner neuroblastic layer.

213 e oxygen reduction reaction (ORR), while the inner Ni-N(4) clusters are responsible for excellent act

214 extensive protein network that underlies the inner nuclear envelope.

215 gher baseline age was associated with faster inner nuclear layer (INL) and outer nuclear layer (ONL)

216 of only the GCL, inner plexiform layer, and inner nuclear layer thickness with rates of -0.11 mum/ye

217 ronic or resolved PAMM lesion was defined as inner nuclear layer thinning with outer plexiform layer

218 ar regression model showed that SSPiM in the inner nuclear layer was related to treatment response (P

219 litudes, and thinned the outer plexiform and inner nuclear layers of both WT and hWtEPOR 8-week-old m

220 NEC deforms the inner nuclear membrane (INM) around the capsid by formin

221 within the nucleus through interactions with inner nuclear membrane (INM) proteins.

222 The inner nuclear membrane is functionalized by diverse tran

223 and the homologous architectures of related inner nuclear membrane proteins(7,8), suggest that phase

224 pose was to study the macular ganglion cell- inner plexiform layer (GC-IPL) thickness in healthy 6.5

225 RNFL) thickness, rim area, and ganglion cell-inner plexiform layer (GC-IPL) thickness measurements we

226 er layer (pRNFL) and macular ganglion cell + inner plexiform layer (GCIPL) thinning in multiple scler

227 etinal nerve fiber layer, ganglion cell plus inner plexiform layer (GCIPL), whole-brain, gray matter

228 l nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL).

229 ness (mRNFL) and macular ganglion cell layer-inner plexiform layer thickness were 3.5, 4.5, 3.0, 3.0,

230 ignificant decline with age of only the GCL, inner plexiform layer, and inner nuclear layer thickness

231 that run in a single, narrow stratum of the inner plexiform layer.

232 r from positively charged amino acids at the inner pore and a voltage-dependent Ca(2+)/Mg(2+) block.

233 ium between resting states (with D4S4 in the inner position) and inactivated states (with D4S4 in the

234 es in a filamentous pattern along regions of inner positive-cell curvature by its coiled-coil motifs,

235 gly, the cis isomer could not be detected in inner prolines, in line with percentages derived from a

236 The inner protein layer, organized as a T = 19 capsid, confi

237 microtubule number and geometry, microtubule inner proteins, and microtubule linkers.

238 nt within the middle region, while outer and inner regions resembled that of control mice.

239 Stability of the inner retina found in these mutants 2 months after PR de

240 way primarily affects the oxygenation of the inner retina involved in signal processing and transduct

241 reporter expression in restricted subsets of inner retina neurons.

242 ter and transmit photoreceptor output to the inner retina, are among the first cells affected by diab

243 gether with the expected vasculopathy in the inner retina.

244 ated with the morphological expansion of the inner retina.

245 There were significantly more deep inner retinal dimples in the temporal group (35%) compar

246 us both ILMP and JPL (16 patients), PPV plus inner retinal fenestration (18 patients), and PPV plus a

247 nto electric current to stimulate the nearby inner retinal neurons.

248 these therapeutic strategies will depend on inner retinal structural and functional preservation.

249 Central foveal thickness (CFT), inner retinal thickness (IRT), outer retinal thickness (

250 C-terminal flexible half emanating from the inner rim of the upper hexon channel into the tegument l

251 The resulting decrease in the inner ring nasal quadrant was 40% greater for VD and 48%

252 of NUCLEOPORIN 205, a core component of the inner ring of the nuclear pore complex (NPC).

253 d astigmatism, the resulting decrease in the inner ring superior quadrant was 12% greater for VD and

254 synthesis (outer ring) and the leading-edge (inner ring) of septal PG (sPG) synthesis.

255 of Type III Dio (Dio3), which deiodinates TH inner rings through a selenocysteine (Sec) residue, reve

256 In situ TEM analysis reveals that the inner Sb nanoparticles undergo a significant volume expa

257 proteins from their site of synthesis in the inner segment (IS) to the outer segment (OS) is critical

258 e arrangement of the mitochondria within the inner segment in detail using three-dimensional (3D) ele

259 ged and had reduced alignment to neighboring inner-segment mitochondria.

260 In rods, arrestin-1 moves from the inner segments and cell bodies in the dark to the outer

261 r photoreceptors are present in the cavefish inner segments, the outer segments of the photoreceptors

262 nions from the inner layer and results in an inner SEI that is thin, dense and inorganic in nature.

263 cross the multi-level interfaces (Si/Li(x)Si/inner-SEI/outer-SEI), thus offering novel insights into

264 sical response to water loss during drought, inner Selaginella lepidophylla stems curl into a spiral

265 e devoid of water because they formed in the inner Solar System.

266 for the C-N bond formation and a potentially inner sphere protodemetallation.

267 step responsible for enantioinduction in the inner-sphere asymmetric Tsuji allylic alkylation is C-C

268 uction from Tc(VII) to Tc(IV) and subsequent inner-sphere complexation of Tc(IV)-Tc(IV) dimers onto a

269 or particle characterization, the breadth of inner-sphere electrochemical reactions makes this a prom

270 These complexes may serve as models for the inner-sphere protonolysis reactions required for catalyt

271 re redox couple (ferrocene methanol) and two inner-sphere redox couples (potassium ferrocyanide and d

272 dvantage to the PCET process by lowering the inner-sphere reorganization energy by limiting the elong

273 The small inner-sphere reorganizations, lambda(i), for Ru(III/II)P

274 none of the complexes has a single, integral inner-sphere water that exchanges rapidly on the NMR tim

275 ands produce single-peak meteotsunami waves, inner spiral rainbands trigger longer lasting wave train

276 the outer medullary collecting duct from the inner stripe (OMCDi) is not known.

277 The impact of the inner structure and thermal history of planets on their

278 ed activity is initiated by ATP release from inner supporting cells (ISCs), resulting in activation o

279 et requires P2RY1 autoreceptors expressed by inner supporting cells.

280 cking or fusion events, whereas those at the inner surface are needed for assembly of selective autop

281 cally adhered onto the roughened part of the inner surface of a fused silica capillary prepared by et

282 On the concave inner surface of mitochondrial cristae, we estimate the

283 Inner surface of T-SQT was coated with molybdenum to enh

284 ion of proteins onto the coated or untreated inner surface of the fused silica capillary was develope

285 The inner surfaces of the human heart are covered by a compl

286 er-diameter heterostructure consisting of an inner SWCNT, a middle three-layer BN nanotube, and an ou

287 rmin ForB favors the actin wave and ForG the inner territory, whereas ForA, ForE, and ForH are more s

288 uced frequency of anoxic incursions onto the inner to mid-ramp is recorded from ~547 Ma onwards, with

289 he same fold as proteins that form the rigid inner tubes of contractile tail phages, such as T4, and

290 not only the number of floral organs in the inner two whorls, but also in the second whorl of the fl

291 The lower-inner (type II) location was the most usual, followed by

292 us of choice: not only what to do, but which inner voice to listen to - our 'automatic' response syst

293 crease the cycling stability by providing an inner void space to accommodate volume changes and a mec

294 ies of mega-electron volts, cold ions in the inner wall surface implode towards the central axis.

295 istic effect originating from the conjugated inner wall, the POF material (aperture size 2.4 nm) conc

296 ecules expelled from single vesicles onto an inner-wall carbon surface, where the duration of transmi

297 reiteration of stamenoid perianth organs in inner whorls and complete loss of carpels.

298 A challenge to understanding the inner workings of these complex magnetoelectric multifer

299 r time'; through the core components of: the inner world, (psyche, emotion and coping); self as embod

300 GCs closer to the white matter (inner-zone GCs) had higher firing thresholds and could s