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1  caused by mutation of the OCRL1 protein, an inositol polyphosphate 5-phosphatase.
2  Inpp5b is an ubiquitously expressed type II inositol polyphosphate 5-phosphatase.
3 ion; and INP53, encoding a synaptojanin-like inositol polyphosphate 5-phosphatase.
4  cerevisiae INP51 locus (YIL002c) encodes an inositol polyphosphate 5-phosphatase.
5  or oculocerebrorenal syndrome (OCRL), is an inositol polyphosphate 5-phosphatase.
6 DXNXR and PXWCDRXL, define a large family of inositol polyphosphate 5-phosphatases.
7 binding sites, and a domain with homology to inositol polyphosphate-5-phosphatases.
8   The Src homology 2 (SH2) domain-containing inositol polyphosphate 5-phosphatase 1 (SHIP1) is an imm
9 encodes the lipid phosphatase SH2-containing inositol polyphosphate 5-phosphatase 1 (SHIP1), is assoc
10 ockdown, we identified SH2-domain containing inositol polyphosphate 5-phosphatase 2 (SHIP2) as the ke
11                  As the [IP3] was increased, inositol polyphosphate 5-phosphatase (5-phosphatase) deg
12 loning and characterization of a novel human inositol polyphosphate 5-phosphatase (5-phosphatase) tha
13 erase; a prenyl-binding protein) and INPP5E (inositol polyphosphate-5-phosphatase 5E).
14 loning strategy and found that it encodes an inositol polyphosphate 5' phosphatase (5PTase).
15                                      The myo-inositol polyphosphate 5-phosphatases (5PTases) (E.C. 3.
16                                          The inositol polyphosphate 5-phosphatases (5PTases) comprise
17                                      Type II inositol polyphosphate 5-phosphatases (5PTases) in yeast
18  D460A, in the 110 kDa form of the signaling inositol polyphosphate 5-phosphatase (5SIP110).
19  triphosphate accumulation upon depletion of inositol polyphosphate-5-phosphatase A, an inositol 5-ph
20  overlapped between MCF-7 and MCF-10A cells: inositol polyphosphate-5-phosphatase A, corticotropin ho
21   Our findings reveal a crucial function for inositol polyphosphate-5-phosphatase A-mediated triphosp
22         The SIP-130 and SIP-145 proteins and inositol polyphosphate 5-phosphatase activity associated
23  amino-terminal regions similar to mammalian inositol polyphosphate 5-phosphatases and to yeast SAC1.
24 tenin complexes), down-regulation of 51C (an inositol polyphosphate-5-phosphatase), and down-regulati
25                                              Inositol polyphosphate 5-phosphatases are central to int
26                                     Numerous inositol polyphosphate 5-phosphatases catalyze the degra
27                            Mice deficient in inositol polyphosphate 5'-phosphatase D (INPP5D, also kn
28                                     The gene inositol polyphosphate-5-phosphatase D (INPP5D), which e
29                                              Inositol polyphosphate-5-phosphatase D (INPP5D/SHIP1) is
30     The disease is caused by mutations in an inositol polyphosphate 5-phosphatase designated OCRL.
31          The 1.8 resolution structure of the inositol polyphosphate 5-phosphatase domain of SPsynapto
32                       Here we show using the inositol polyphosphate 5'-phosphatase E (INPP5E) and the
33 phate (PtdIns(4)P) 5-kinase (PIPKIgamma) and inositol polyphosphate-5-phosphatase E (INPP5E), a Joube
34 ibe a protein-protein interaction network of inositol polyphosphate-5-phosphatase E (INPP5E), a preny
35 s, we identified a functional null allele of inositol polyphosphate-5-phosphatase E (Inpp5e), ridge t
36 ified mutations in the INPP5E gene, encoding inositol polyphosphate-5-phosphatase E, which hydrolyzes
37                                          The inositol polyphosphate-5-phosphatase enzyme family now i
38 th increased expression of the gene encoding inositol polyphosphate-5-phosphatase f (Inpp5f) resultin
39                    Here, we demonstrate that Inositol Polyphosphate-5-Phosphatase F (INPP5F), one of
40 tic vesicles and shown to be a member of the inositol polyphosphate 5-phosphatase family.
41 ducts of a single gene and as members of the inositol polyphosphate 5-phosphatase family.
42 pleckstrin in platelets is in a complex with inositol polyphosphate 5-phosphatase I (5-phosphatase I)
43 ited in cells microinjected with recombinant inositol polyphosphate 5-phosphatase I, which degrades i
44 ermed SIP-145 and SIP-130 (SIP for signaling inositol polyphosphate 5-phosphatase), identified them a
45 ating each to alanine in the platelet 75 kDa inositol polyphosphate 5-phosphatase II (5-phosphatase I
46 tal of 970 amino acids that is homologous to inositol polyphosphate 5-phosphatase II.
47 ms of two other 5-phosphatases designated as inositol polyphosphate-5- phosphatase II, and OCRL (the
48        These findings strongly implicate the inositol polyphosphate 5-phosphatases in Shc- and Grb2-m
49 tially suppressed by a mutation in IPP-5, an inositol polyphosphate 5-phosphatase, indicating that on
50 emically-induced dimerization to translocate inositol polyphosphate 5-phosphatase (Inp54p) to plasma
51 P(2) pool by plasma membrane targeting of an inositol polyphosphate-5-phosphatase (Inp54p) blocked PL
52  Ocrl1 deficiency is complemented in mice by inositol polyphosphate 5-phosphatase (Inpp5b), an autoso
53 ant functions of OCRL and its paralog type 2 inositol polyphosphate-5-phosphatase (INPP5B).
54 cible proapoptotic targets of p53, including inositol polyphosphate-5-phosphatase (INPP5D), pleckstri
55                                          The inositol polyphosphate 5-phosphatase INPP5E localizes to
56                           We showed that the inositol polyphosphate 5-phosphatase INPP5K regulates au
57 s constitutively expressing the human type I inositol polyphosphate 5-phosphatase (InsP 5-ptase), an
58 cells were transformed with the human type I inositol polyphosphate 5-phosphatase (InsP 5-ptase), an
59 liana plants expressing the mammalian type I inositol polyphosphate 5-phosphatase (InsP 5-ptase), whi
60                                      Type II inositol polyphosphate 5-phosphatases (IPPs) act on both
61                                     OCRL, an inositol polyphosphate 5-phosphatase, is mutated in Lowe
62 bisphosphate even though at least four other inositol polyphosphate 5-phosphatase isozymes are presen
63                    Phosphoinositide-specific inositol polyphosphate 5- phosphatase IV has the affinit
64 drolase 1 (Nceh1), adenylate kinase 1 (Ak1), inositol polyphosphate 5-phosphatase J (Inpp5j), ATP syn
65                          We explored whether inositol polyphosphate-5-phosphatase K (Inpp5k) could en
66                           INPP5K encodes the inositol polyphosphate-5-phosphatase K, also known as SK
67 ied bi-allelic mutations in INPP5K, encoding inositol polyphosphate-5-phosphatase K.
68  is also present at the amino termini of the inositol polyphosphate 5-phosphatases, mammalian synapto
69 tions and that substrates and/or products of inositol polyphosphate 5-phosphatases may have roles in
70               Mutations in OCRL encoding the inositol polyphosphate 5-phosphatase OCRL (Lowe oculocer
71 eans, by overexpression of the TGN-localized inositol polyphosphate 5-phosphatase Ocrl, or by blockad
72                                  Encoding an inositol polyphosphate 5-phosphatase, OCRL catalyzes the
73  Arabidopsis 5PTase13 gene, which encodes an inositol polyphosphate 5-phosphatase previously shown to
74 We have identified this protein as the novel inositol polyphosphate 5-phosphatase (SHIP).
75             Src homology-2 domain-containing inositol polyphosphate-5'-phosphatase (SHIP) also bound
76 tor activation by inhibitory coreceptors: an inositol polyphosphate 5'-phosphatase, SHIP, and a tyros
77 the recruitment of the SH2-domain-containing inositol polyphosphate 5-phosphatase, SHIP, to the tyros
78                    The SH2 domain-containing inositol-polyphosphate 5-phosphatase, SHIP, associates w
79 of PI3,4,5P3 into PI3,4P2 with the signaling inositol polyphosphate 5' phosphatase SIP.
80                                           An inositol polyphosphate-5-phosphatase (SIP-110) that bind
81 although it hydrolyzes all four of the known inositol polyphosphate 5-phosphatase substrates: inosito
82 utations in both CVP2 and CVL1, which encode inositol polyphosphate 5'-phosphatases that generate the
83 udied INPP5A, a farnesylated, membrane-bound inositol polyphosphate 5-phosphatase that degrades IP3.
84 nsive homology to the SH2 domain of SHIP, an inositol polyphosphate 5-phosphatase that functions as a
85                  We found that VPA0450 is an inositol polyphosphate 5-phosphatase that hydrolyzed the
86    The subcellular localization of Ocrl, the inositol polyphosphate 5-phosphatase that is mutated in
87   Previous studies revealed that INPP5E, the inositol polyphosphate-5-phosphatase that is mutated in
88      Antibodies raised against the 51C/SHIP2 inositol polyphosphate 5'-phosphatase were used to exami
89                             OCRL1 encodes an inositol polyphosphate 5-phosphatase which preferentiall
90 approximately 10-fold greater than the other inositol polyphosphate 5-phosphatases, which use this su
91                           The association of inositol polyphosphate 5-phosphatase with FcgammaRIIB su
92           SIP is a phosphatidylinositol- and inositol-polyphosphate 5-phosphatase with specificity in