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1 high levels as a result of a third mutation (insertion sequence).
2 ix domain, and a transmembrane and cytosolic insertion sequence.
3 f an internal 57-amino-acid-long hydrophobic insertion sequence.
4 when there are fewer than five copies of the insertion sequence.
5 with olefins via a C-H activation, migratory insertion sequence.
6 /- 31 900 different, EpiSC-specific, peptide insertion sequences.
7 ene, an intein (Cbu.DnaB) within dnaB and 29 insertion sequences.
8 or ammonia catabolism, iron acquisition, and insertion sequences.
9 polymorphisms, and a unique distribution of insertion sequences.
10 racketed by the homologous ISV-A1 and ISV-A2 insertion sequences.
11 st of which locate to intergenic regions and insertion sequences.
12 S1601 contains portions of three independent insertion sequences.
13 tive composite transposon bracketed by IS600 insertion sequences.
14 nucleotide changes, and the transposition of insertion sequences.
15 deletion via recombination between flanking insertion sequences.
16 harbors at least 12 copies of five distinct insertion sequences.
17 ation of the composite transposon's flanking insertion sequences.
18 ral mechanism for the formation of miniature insertion sequences.
19 n of all genomic rearrangements that involve insertion sequences.
20 re recognized: 13 capsule synthesis genes, 4 insertion sequences, 1 truncated biosynthesis gene, and
21 h several genomic rearrangements mediated by insertion sequences, 12 cryptic prophages, 372 pseudogen
22 time PCR assay with three targets, including insertion sequence 481 (IS481), IS1001, and an IS1001-li
23 in the United States, most laboratories use insertion sequence 481 (IS481), which is not specific fo
24 ary 1, 2001, and December 31, 2003, that had insertion sequence 6110 (IS6110) restriction fragment le
26 tative virulence genes, genomic islands, and insertion sequences across a collection of 33 strains is
29 ogenic bacterial plasmid "mobilome" includes insertion sequence and other transposable elements that
30 on is unusually G-C rich, and it has unusual insertion sequences and a minimal dependence on the EBS2
31 ing, sap typing, and the presence/absence of insertion sequences and a type I restriction modificatio
33 ither singly or in large multiple arrays, to insertion sequences and gene duplications of one kilobas
34 ools such as Optimized Annotation System for Insertion Sequences and IScan currently identify IS elem
35 plicated by the presence of repeat elements, insertion sequences and other similar factors that contr
36 strain chi7122 include complete and partial insertion sequences and phage-related DNA sequences, som
37 Divergent features included already reported insertion sequences and ragB, as well as additional hypo
39 omosome of each recipient, where it acquired insertion sequences and underwent deletions and rearrang
40 ransposon mutant library that is amenable to insertion sequencing and introduced this mutant pool int
41 olerae survival, and by combining transposon-insertion sequencing and transcriptomic data sets, we al
42 es-specific hypothetical genes, transposons, insertion sequences, and integrases and were located adj
44 d contains an unusual t-RNA island, numerous insertion sequences, and large repeated elements, includ
46 ae are spread by plasmid-mediated integrons, insertion sequences, and transposons, some of which are
47 ke other obligate intracellular bacteria, 32 insertion sequences are found dispersed in the chromosom
49 mino acids of the peptide, also known as the insertion sequence, are found to be essential in reducin
51 none of the C2 isolates) carried IS1016 (an insertion sequence associated with H influenzae capsule
53 TA proteins possess a hydrophobic membrane insertion sequence at their C-terminus such that it can
55 region of selenoprotein mRNAs as well as Sec insertion sequence binding protein 2, Sec-tRNA(Sec), and
56 by a multiprotein complex that includes Sec insertion sequence-binding protein 2 (SECISBP2; also kno
58 transposase, a member of the IS256 family of insertion sequences, bound to DNA substrates correspondi
59 rs to play a central role in the exchange of insertion sequences, but not the exchange of high-identi
60 ns of C. reinhardtii have short extension or insertion sequences, but overall the large subunit prote
61 ntify thousands of MGEs, including candidate insertion sequences, conjugative transposons, and propha
63 present a resource and analysis of 2,363 new insertion sequences corresponding to 720 genomic loci.
67 ruption in the A genome include retroelement insertions, sequence deletions, and mutations causing in
69 uence similarities to known genes, including insertion sequences, determinants of regulatory proteins
72 eatures of the cDNA include a selenocysteine insertion sequence element approximately 4.8 kb 3' to th
76 g from stop to Sec involves a cis-acting Sec insertion sequence element in the 3' untranslated region
77 ) and its insertion was dependent on the Sec insertion sequence element in the 3'UTR of TR1 mRNA.
78 rs713041 is located near the selenocysteine insertion sequence element in the GPX4 3' untranslated r
79 hia coli K-12 strain MG1655 contained an IS1 insertion sequence element in the regulatory region of t
81 lis: (i) the transposition of the endogenous insertion sequence element IS1126 and (ii) the modulatio
82 determined that the endogenous P. gingivalis insertion sequence element IS1126 is capable of transpos
85 depends on the nature of the selenocysteine insertion sequence element located in the 3' UTR of sele
86 the presence of a functional selenocysteine insertion sequence element that is highly active but onl
87 gly, however, we also observed that a 1.8-kb insertion sequence element was positioned between ccmB a
88 expressed when the Drosophila selenocysteine insertion sequence element was used, whereas the corresp
94 parent strain using all known P. gingivalis insertion sequence elements as probes suggested that no
95 idence that homologous recombination between insertion sequence elements can be a primary determinant
98 conversion and several other loci containing insertion sequence elements or phage-related gene insert
99 gingivalis was a concerted up-regulation of insertion sequence elements related to IS1 transposases.
100 se genes, conjugative functions and multiple insertion sequence elements suggests that the PAI, or se
103 em-loop structures resembling selenocysteine insertion sequence elements were identified in the 3'-un
105 frame is homologous to a family of putative insertion sequence elements, although our evidence shows
106 vel program that searches for selenocysteine insertion sequence elements, followed by selenoprotein g
107 PXO99A contains numerous copies of diverse insertion sequence elements, members of which are associ
111 enome, characterized by a very high level of insertion sequences elements (ISs) and DNA repeats, for
113 ariable deletion events between the flanking insertion-sequence elements, all resulting in eliminatio
114 including phage-derived genes, plasmids, and insertion-sequence elements, highlighting its dynamic na
115 o high-throughput DNA sequencing (transposon-insertion sequencing) enables simultaneous and genome-wi
116 analysis of BiXyn10A demonstrated that such insertion sequences encode a new family of carbohydrate-
117 g decay through loss of functional genes and insertion sequence expansion, often indicative of adapta
118 ar homologous recombination occurred between insertion sequences following an initial transposition e
120 cise, reading frame-restoring excision of an insertion sequence from the coding region of expR, a gen
123 bile genetic elements such as transposons or insertion sequences, i.e. they possess direct repeats at
126 single event, the transposition of an IS6110 insertion sequence in one of the strains, accounted for
127 designated ISPpu12, had the structure of an insertion sequence in that it was bordered by 24-bp near
129 ility of internal deletion variants of other insertion sequences in these isolates suggests that this
130 om multiple inversions of genome segments at insertion sequences, in a manner consistent with present
131 the sea urchin Tsp family and Drosophila SGM insertion sequences; in addition, they possess regions o
132 Recent studies revealed that a hydrophobic insertion sequence (INS) in these LAADs also interacts w
133 directed insertion site sequencing (TraDIS), insertion sequencing (INSeq) and high-throughput inserti
136 ersed repetitive elements (SINEs), and of an insertion sequence (InsIpCHSD) found in the neighborhood
137 onal events involved the transposition of an insertion sequence into a narrow window of a single gene
138 Molecular fingerprinting with the IS6110 insertion sequence is useful for tracking transmission o
140 addition to homologs of two other H. pylori insertion sequence (IS) element genes, orfA, which encod
141 quence studied is derived from a Roseiflexus insertion sequence (IS) element where the resulting tran
142 Streptomyces scabies 84.34 identified a new insertion sequence (IS) element, IS1629, with homology t
143 up (SFG) R. peacockii, we identified a novel insertion sequence (IS) element, ISRpe1, disrupting the
144 ed many of the lines for mutations involving insertion sequence (IS) elements and identified two gene
145 her elements such as transposons, integrons, insertion sequence (IS) elements and the 'new' ISCR (IS
149 ly syntenous, recombination between abundant insertion sequence (IS) elements has resulted in genome
150 ns within functional cps loci, consisting of insertion sequence (IS) elements in unique positions tha
151 he 16 kb region in P. furiosus is flanked by insertion sequence (IS) elements with inverted and direc
152 espite its small size, the genome harbors 73 insertion sequence (IS) elements, almost all of which ar
153 ltiple members of two classes of Francisella insertion sequence (IS) elements, ISFtu1 and ISFtu2, and
154 e plasmid harbors a 16-kb region, flanked by insertion sequence (IS) elements, that encodes the restr
155 , we present genetic maps of recently active Insertion Sequence (IS) elements, the simplest form of M
159 of these were related to known and putative insertion sequence (IS) elements; no known bacterial pla
162 1998, for which the W family was defined by insertion sequence (IS) IS6110 DNA fingerprinting, polym
164 a highly diagnostic set of markers based on insertion sequence (IS) site polymorphism and genomic re
165 G1655, resulting from a dramatic increase in insertion sequence (IS) transposition, especially IS150.
166 ssibility, we have studied the occurrence of insertion sequence (IS)-like elements in P. gingivalis W
167 d hurdle, DNA-protein crosslinking (DPC), by insertion sequence (IS)-mediated copy number variations
168 ycobacterium tuberculosis isolates underwent insertion sequence (IS)6110 restriction-fragment-length
175 he isolates resulted from the presence of an insertion sequence, IS1301, in the intergenic region (IG
176 the ser2 gene cluster are flanked by a novel insertion sequence (IS1601) oriented as direct repeats.
177 three of these isolates, a newly discovered insertion sequence, IS1630 (of the IS30 class), was loca
179 se-developed PCR test targeting the repeated insertion sequence IS481 for the detection of Bordetella
192 tial mobile units (PMUs), which contain tra5 insertion sequences (ISs) and genes for specialized sigm
193 Analyses of complete genomes indicate that insertion sequences (ISs) are abundant and widespread in
198 nd B. holmesii was developed using multicopy insertion sequences (ISs) in combination with the pertus
202 A-2-3B'a(2-13) each host several families of insertion sequences (ISSoc families) at various copy num
203 Both tet(X3) and tet(X4) are adjacent to insertion sequence ISVsa3 on their respective conjugativ
205 Tandem amplification occurs via the flanking insertion sequences, leading to increased toxin producti
207 anatomical images, transgenic constructs and insertions, sequence-level gene models and molecular cla
209 asses: (i) proviruses, (ii) casposons, (iii) insertion sequence-like transposons, (iv) integrative-co
212 r bacterial NusG proteins contain a variable insertion sequence of approximately 70 residues in the c
213 performed DNA fingerprinting with the IS6110 insertion sequence of the organisms isolated from patien
214 this hypothesis, a mutation in the membrane insertion sequence of the v-SNARE synaptobrevin/vesicle-
216 cur through homologous recombination between insertion sequences on both sides of a duplicated region
217 i are bracketed by or are in the vicinity of insertion sequences or long clusters of tandem repeats (
218 inding could be explained by the presence of insertion sequences or mutations in O-antigen or lipopol
219 me is unusual in that there are virtually no insertion sequences or phage-associated sequences and ve
224 lation, but loss of a downstream pyrrolysine insertion sequence (PYLIS) significantly increased the U
225 a dynamic 2,571,010-bp genome containing 91 insertion sequences representing 12 families and organiz
226 archy of selenoprotein synthesis are the Sec insertion sequence RNA-binding proteins, SBP2 and nucleo
228 cess are the mRNA binding protein of the Sec insertion sequence, SBP2, and the specialized elongation
230 a 3 untranslated region (UTR) selenocysteine insertion sequence (SECIS) and the SECIS-binding protein
231 ing event is specified by the selenocysteine insertion sequence (SECIS) element and requires the sele
233 c in mammalian selenoproteins requires a Sec insertion sequence (SECIS) element in the 3' untranslate
234 codon as selenocysteine (Sec) requires a Sec insertion sequence (SECIS) element in the 3' untranslate
235 re a set of highly specific factors: the Sec insertion sequence (SECIS) element in the 3' untranslate
236 rporation into selenoproteins requires a Sec Insertion Sequence (SECIS) element in the 3' untranslate
238 ec-dedicated elongation factor SelB to a Sec insertion sequence (SECIS) element in the selenoprotein-
239 ated at UGA codons in mRNAs possessing a Sec insertion sequence (SECIS) element in their 3'-untransla
240 egion of this gene contains a selenocysteine insertion sequence (SECIS) element that deviates at one
241 two copies of tRNA-Sec and a selenocysteine insertion sequence (SECIS) element which were lost in pl
242 of UGA as Sec depends on the selenocysteine insertion sequence (SECIS) element, a stem-loop structur
243 aryotes, incorporation of Sec requires a Sec insertion sequence (SECIS) element, a stem-loop structur
244 a common stem-loop structure, selenocysteine insertion sequence (SECIS) element, that is necessary fo
246 ependent on the presence of a selenocysteine insertion sequence (SECIS) element, which recruits the s
254 ppresses UGA codons that are upstream of Sec insertion sequence (SECIS) elements bound by SECIS-bindi
255 ly structured 3' UTR contains selenocysteine insertion sequence (SECIS) elements that are required fo
256 selenoprotein genes contained selenocysteine insertion sequence (SECIS) elements that were similar, b
257 y identified several genes with multiple Sec insertion sequence (SECIS) elements, one of which was a
258 for evolutionarily conserved selenocysteine insertion sequence (SECIS) elements, which are RNA struc
260 n selenoproteins depends on a selenocysteine insertion sequence (SECIS) in the 3'-UTR of mRNAs of euk
261 gency of the Escherichia coli selenocysteine insertion sequence (SECIS) requirements, libraries of SE
262 sertion requires a cis-acting selenocysteine insertion sequence (SECIS) usually located in the 3'UTR
263 untranslated region, termed a selenocysteine insertion sequence (SECIS), and SECIS-binding protein 2
264 ires the TGA opal codon and a downstream Sec insertion sequence (SECIS), which can be partially rando
266 tructure and stability of the selenocysteine insertion sequences (SECIS) of human glutathione peroxid
268 e subspecies and is bracketed by remnants of insertion sequences, suggesting a multistep process in t
271 kynyliodonium salt/alkylidenecarbene/1,5 C-H insertion sequence that sets the pivotal quaternary cent
272 Downstream from the termination codon is an insertion sequence that was homologous to the ISVs1 elem
274 pproximately 5% of the genome is composed of insertion sequences that may contribute to genome rearra
275 ntify the chromosomal position of repetitive insertion sequences that typically flank horizontally ac
276 xpression levels of endogenous and exogenous insertion sequences that were 2 orders of magnitude high
277 uctural features, pathognomonic of a regular insertion sequence, this element was designated IS1414.
278 since the introduction of modern transposon-insertion sequencing (TIS) methods, which combine genome
280 e-gene deletion strains and a new transposon insertion sequencing (Tn-Seq) dataset that we generated.
288 previously developed the Transposon Directed Insertion Sequencing (TraDIS) protocol for this purpose,
290 e analysis revealed the presence of multiple insertion sequences upstream and downstream of the aerob
291 ion studies of Acinetobacter baylyi ADP1, an insertion sequence was evident in approximately 2% of th
294 a-D-glucosidase gene, with a novel PA14-like insertion sequence, was identified two genes downstream
295 As in the absence of thiI Through transposon insertion sequencing, we identified additional tRNA modi
298 ed OASIS, or Optimized Annotation System for Insertion Sequences, which automatically annotates ISs w
299 in is distinctive in its large complement of insertion sequences, with several genomic rearrangements
300 ces, a Y chromosome-specific sequence, or an insertion sequence within the glutathione S-transferase