ライフサイエンスコーパス: insular cortex

1 reward processing (right amygdala and fronto-insular cortex).

2 and right inferior parietal lobes and right insular cortex.

3 rs the signature of autonomic arousal in the insular cortex.

4 taste memory and AMPA receptor expression in insular cortex.

5 he parabrachial nucleus, and projects to the insular cortex.

6 , subgenual anterior cingulate, and anterior insular cortex.

7 NMDAR-dependent CaMKII- AMPAR pathway in the insular cortex.

8 ed the cerebellum, hippocampus, amygdala and insular cortex.

9 gating of cardiac-related information in the insular cortex.

10 mapping of vestibular responses in the human insular cortex.

11 ecially within adjacent posterior regions of insular cortex.

12 th low-fat meals on the hypothalamus and the insular cortex.

13 y portion of the thalamus, and the gustatory insular cortex.

14 me reduction in orbitofrontal, cingulate and insular cortex.

15 and conditioned taste aversion memory in the insular cortex.

16 by brain mechanisms that do not require the insular cortex.

17 ilar finding involving NMDA receptors in the insular cortex.

18 but also in auditory, visual, entorhinal and insular cortex.

19 cleus of the stria terminalis but not in the insular cortex.

20 lateral hypothalamus, central amygdala, and insular cortex.

21 e thalamus, second somatosensory cortex, and insular cortex.

22 reactivity (FLI) in the central amygdala and insular cortex.

23 ut decreased NGF and BDNF mRNA levels in the insular cortex.

24 stributions of neurons in the prefrontal and insular cortex.

25 ion and lysine acetyltransferase activity in insular cortex.

26 ctivities along with the ERK/MAPK cascade in insular cortex.

27 rgets of the gustatory system, including the insular cortex.

28 he anterior extreme capsule white matter and insular cortex.

29 calbindin neurons, at least within Anterior Insular Cortex.

30 to restore hunger-like response patterns in insular cortex.

31 ns, like the putamen with connections to the insular cortex.

32 he lateral pallium at the site of the future insular cortex.

33 he pial surface to form layers (2-6a) of the insular cortex.

34 lose to the external capsule and deep in the insular cortex.

35 tatory responses to stimulation of the human insular cortex.

36 y covered by the Nr4a2-negative cells of the insular cortex.

37 ecting that of long-term potentiation in the insular cortex.

38 ng signal (prediction error) in the anterior insular cortex.

39 What is the function of the insular cortex?

40 not AM251, infusions into the interoceptive insular cortex (a region known to be activated in acute

41 We hypothesized that the right mid-insular cortex, a central recipient of viscerosensory in

42 tivated protein kinase (MAPK)/RSK cascade in insular cortex, a CNS region known to be crucial for the

43 ral and functional abnormalities in the left insular cortex, a region also implicated in individuals

44 ocessing (left lateral prefrontal and fronto-insular cortex), action execution and pain processing (r

45 d 10% to 15% of the variance in amygdala and insular cortex activation to emotional faces.

46 ls related to subclinical anxiety levels and insular cortex activation.

47 ctivation in both regions; however, only the insular cortex activations are significantly associated

48 The anterior insular cortex (AI) was the only brain region examined w

49 cortex (PrL) interactions with the anterior insular cortex (aIC) and dorsal hippocampus (dHPC) in re

50 ror-associated regions, such as the anterior insular cortex (aIC) and rostral anterior cingulate cort

51 l regions in rats, the agranular/dysgranular insular cortex (AIC) and the ventromedial prefrontal cor

52 foundation for a role of the human anterior insular cortex (AIC) in emotional awareness, defined as

53 Consistent with an anterior insular cortex (AIC) involvement in storing taste memori

54 w that activation of neurons in the anterior insular cortex (aIC) that project into the basolateral a

55 The right anterior insular cortex (AIC) was identified as the principal are

56 l-dependent (BOLD) responses in the anterior insular cortex (AIC), a core hub of the "salience networ

57 Activity in anterior insular cortex (AIC), premotor cortex (PMd), and inferio

58 atosensory cortex, retrosplenial cortex, and insular cortex also contained tdTomato-labelled neurons.

59 d to be expressed across the olfactory bulb, insular cortex, amygdala, and dorsal hippocampus.

60 ronal ensembles in the orbitofrontal cortex, insular cortex, amygdala, and nucleus accumbens while ra

61 ial temporal lobe, with values of 1.6 in the insular cortex and 0.7-1.0 in other cortical regions.

62 order) and with increased limbic activation (insular cortex and amygdala) during emotion processing (

63 D2 receptor binding in the salience network (insular cortex and anterior cingulate cortex [ACC] and t

64 on group exhibited regional CBF increases in insular cortex and anterior cingulate gyrus; increases i

65 erior temporal area extending to include the insular cortex and basal ganglia, lateralizing to the si

66 ness of Ce output neurons to inputs from the insular cortex and BLA.

67 body and to the modulation of pain (anterior insular cortex and brainstem, respectively) determines w

68 ral striatum), but also aversive processing (insular cortex and cerebellum).

69 owth of the frontotemporal opercula over the insular cortex and compared the transcriptome of the dev

70 ears exhibited an enhanced response in right insular cortex and decreased response in right prefronta

71 assessed high-signal-intensity areas in the insular cortex and extreme capsule on coronal MR images

72 rCBF in the vicinity of the hypothalamus and insular cortex and in additional paralimbic and limbic a

73 ontrol was associated with reduced volume in insular cortex and increased volume of caudate nucleus.

74 ructural brain abnormalities implicating the insular cortex and limbic system.

75 iation between increased gyrification of the insular cortex and memory function, specifically observe

76 insula is an interface between the posterior insular cortex and motor cortex and is connected with mo

77 ack of layer IV, was defined as the temporal insular cortex and named as area TI after Beck.

78 ing of the multiple sensory functions of the insular cortex and of the cortical processing of vestibu

79 , caudate nucleus, anterior cingulate gyrus, insular cortex and orbitofrontal cortex).

80 lation of neurons in this structure, and the insular cortex and the basolateral amygdala (BLA) intera

81 ersus neutral stimuli were found in the left insular cortex and the left anterior cingulate.

82 re distributed most densely in the agranular insular cortex and the paraventricular nuclei of the tha

83 thalamus, as well as metabolic decreases in insular cortex and the periaqueductal gray, were noted.

84 e posterior insula, that is, in the granular insular cortex and the postcentral insular gyrus.

85 ral sheet of gray matter located between the insular cortex and the striatum.

86 ocentric paralimbic regions of interest, the insular cortex and the temporal pole, were evaluated.

87 s, such as the primary somatosensory cortex, insular cortex, and ACC.

88 lateral hypothalamus, orbitofrontal cortex, insular cortex, and amygdala of hungry rats that volunta

89 ivated sites within the medial frontal lobe, insular cortex, and cerebellum distinct from, but close

90 cFos immunohistochemistry and found that the insular cortex, and other regions, are activated followi

91 er volume in medial prefrontal cortex (PFC), insular cortex, and subgenual anterior cingulate regions

92 ial prefrontal cortices, anterior cingulate, insular cortex, and superior temporal gyrus.

93 ate, the dorsolateral prefrontal cortex, the insular cortex, and the nucleus accumbens.

94 btained in patients with MDD in the anterior insular cortex, anterior and posterior thalamus, ventral

95 Amygdaloid projections from the posterior insular cortex appear to be organized in a feedforward p

96 hes, including viral vector transfections of insular cortex, arc fluorescence in situ hybridization (

97 e ventromedial prefrontal cortex (vmPFC) and insular cortex are implicated in distributed neural circ

98 s to determine whether NMDA receptors in the insular cortex are involved in this experience-dependent

99 d found that the visual-vestibular posterior insular cortex area was less activated during attentive

100 eural activity in the visual, cerebellar and insular cortex areas compared with a resting condition.

101 oint at macroscopic representations in human insular cortex as a complex function of taste category a

102 veral brain regions, including the bilateral insular cortex, bilateral precuneus/posterior cingulate

103 served decreased binding specifically in the insular cortex bilaterally.

104 the posterolateral orbitofrontal cortex and insular cortex bilaterally.

105 Electrolytic lesions of insular cortex blocked behavioral expression of a condit

106 evate FLI expression in central amygdala and insular cortex, but also failed to induce stronger taste

107 his pattern was seen in central amygdala and insular cortex, but not in basolateral amygdala, parabra

108 ain areas, the anterior cingulate cortex and insular cortex, but not in the spinal cord.

109 covery of von Economo neurons within macaque insular cortex by Evrard et al. described in this issue

110 Damage to the insular cortex can profoundly disrupt tobacco addiction

111 The insular cortex cells, which are born later and which are

112 atosensory representation in caudal granular insular cortex (CGIC) in the rat, either before or after

113 satiety-related visceral signals converge in insular cortex, chemogenetic activation of hypothalamic

114 ding dorsolateral prefrontal cortex (dlPFC), insular cortex, cingular cortex, and the basal ganglia d

115 signated histogenetic unit gives rise to the insular cortex/claustrum and should therefore be conside

116 ing seven clusters across frontoparietal and insular cortex comparable to human MD regions and one un

117 esponses to disgusted faces in the bilateral insular cortex compared with healthy controls.

118 ed by anterograde tracer injections into the insular cortex, corticothalamic projections in the VPMpc

119 unctionally dissociable effects of vmPFC and insular cortex damage.

120 um, consistent with classical definitions of insular cortex dating back to Rose.

121 s that this is dissociable from the adjacent insular cortex-dependent taste aversion memory.

122 essing, they make evident that the region of insular cortex destroyed is not necessary for the normal

123 ene blue increased response in the bilateral insular cortex during a psychomotor vigilance task (Z =

124 regions within the human frontal cortex and insular cortex during food desirability choices, combine

125 atric and neurological disorders impacted by insular cortex dysfunction, including autism, schizophre

126 alamic activity and the interaction with the insular cortex elicited by fat may contribute to an effi

127 odel of awareness proposes that the anterior insular cortex engenders feelings that provide an amodal

128 propose that inflammation restricted to the insular cortex enhances associative taste memory through

129 cortex in auditory processing, with the left insular cortex especially responsive to linguistic stimu

130 terior dorsal insula, such that a portion of insular cortex forms an isolated pocket medial to the Sy

131 CTA depends on the gustatory portion of the insular cortex (GC) and the basolateral nucleus of the a

132 he past decade has established the gustatory insular cortex (GC) as a model for studying how primary

133 nization of taste responses in the gustatory insular cortex (GC) is currently debated, with conflicti

134 g approaches to delineate the likely area of insular cortex given to gustatory function and to charac

135 A bilateral volume reduction in insular cortex gray matter was specific to first-episode

136 The anterior insular cortex (IC) and the nucleus accumbens (NAc) core

137 Previous findings indicate the insular cortex (IC) and the nucleus accumbens (NAc) play

138 Lesions of the insular cortex (IC) attenuate acquisition of conditioned

139 Insular cortex (IC) contributes to a variety of complex

140 l amygdala (BLA) and the gustatory region of insular cortex (IC) have been implicated in these proces

141 e present study investigated the role of the insular cortex (IC) in morphine-induced conditioned tast

142 Insular cortex (IC) is recognized as a potential site fo

143 We examined the influence of insular cortex (IC) lesions on morphine-induced suppress

144 present experiment examined the influence of insular cortex (IC) lesions on the intake of a taste sti

145 the influence of excitotoxic lesions of the insular cortex (IC) on taste-potentiated odor aversion (

146 The insular cortex (IC) plays key roles in emotional and reg

147 strate that partial depletion of 5-HT in the insular cortex (IC) prevents LiCl-induced conditioned di

148 tudies suggest that the anterior part of the insular cortex (IC) serves as primary taste cortex, wher

149 the posterior half of GC in addition to the insular cortex (IC) that is just dorsal and caudal to th

150 a significant increase in ACh release in the insular cortex (IC), a highly relevant structure for tas

151 stronger Fos-like immunoreactivity (FLI) in insular cortex (IC), amygdala, and brainstem than famili

152 The insular cortex (IC), an area largely studied in rodents

153 Prior studies suggest that the insular cortex (IC), and particularly its posterior regi

154 apped a discrete cortico-limbic loop between insular cortex (IC), central amygdala (CE), and nucleus

155 This pattern depends upon the insular cortex (IC), which is anatomically connected to

156 To that aim, insular cortex (IC)-dependent positive and negative form

157 nucleus of the stria terminalis (BNST), and insular cortex (IC).

158 extracellular acetylcholine (ACh) levels in insular cortex (IC).

159 s designed to examine whether lesions of the insular cortex (IC; Experiment 1), the basolateral amygd

160 In the insular cortex, IL1beta enhanced IL6 mRNA and TNFalpha i

161 r-bound protons, within a discrete region of insular cortex implicated in representing internal physi

162 The specific role of insular cortex in acquisition and expression of a condit

163 tion of those stimuli and implicate anterior insular cortex in auditory processing, with the left ins

164 nvestigated the functional properties of the insular cortex in behaving monkeys using intracortical m

165 es have challenged the necessary role of the insular cortex in both awareness and feeling by showing

166 tion, supporting a critical role of anterior insular cortex in empathetic pain processing.

167 olinergic neurotransmission in the posterior insular cortex in neuropathic pain condition and the inv

168 onnectivity, and fALFF converged in the left insular cortex in patients with FXS.

169 we demonstrate a causal role of the anterior insular cortex in relapse to alcohol seeking after exten

170 ds of winning, consistent with a role of the insular cortex in signalling the probability of aversive

171 However, the role of the insular cortex in such modulatory processes remains poor

172 ior cingulate cortex (ACC) and the posterior insular cortex in the anxiodepressive, sensory, and affe

173 nversely, we report a signal in the anterior insular cortex in the highest earners that precedes the

174 Involvement of insular cortex in the induction of c-Fos-immunoreactivit

175 suggests a prominent role of dorsal anterior insular cortex in the parasympathetic control of cardiac

176 pite numerous studies suggesting the role of insular cortex in the processing of gustatory and olfact

177 uroimaging studies in humans have implicated insular cortex in these phenomena.

178 tion on visual awareness and the role of the insular cortex in this process remain unclear.

179 h the thinness of the anterior region of the insular cortex, in which highly impulsive (HI) rats expr

180 We demonstrated that anterior insular cortex inputs are the sole inputs that express a

181 f the intralaminar complex (PINT) and caudal insular cortex (INS) block acquisition but not expressio

182 The insular cortex (INS) is extensively connected to the cen

183 While human insular cortex (InsCtx) is implicated in interoception,

184 We identified the insular cortex (insula), a region involved in regulating

185 functional areas of the brain including the insular cortex (involved in enteroceptive monitoring) an

186 The human insular cortex is a heterogeneous brain structure which

187 As the insular cortex is a well-established region in pain proc

188 We suggest that fusion between temporal and insular cortex is an example of a relatively rare neuroa

189 The insular cortex is anatomically positioned to serve as on

190 The rostral perirhinal border with insular cortex is at the extreme caudal limit of the cla

191 The insular cortex is fundamentally involved in the processi

192 QR2 mRNA expression in the insular cortex is inversely correlated with mAChR activa

193 al conditioning, the gustatory region of the insular cortex is involved in encoding the taste of food

194 The insular cortex is involved in the perception of interoce

195 Additional activation observed in the insular cortex is proposed to be involved in conveying a

196 The insular cortex is required for CTA memory formation and

197 e processing of interoceptive signals in the insular cortex is thought to underlie self-awareness.

198 thalamus, putamen, and pallidum), as well as insular cortex, is associated with greater change in bel

199 the left IFG and left pallidum, putamen, and insular cortex, is associated with reduced change in bel

200 the gustatory cortex, including parts of the insular cortex, is crucial for the processing of food it

201 an assemblage of taste-responsive neurons in insular cortex, is widely regarded as integral to condit

202 Expression in insular cortex, lateral septal nucleus, medial preoptic

203 ces of pain remained present after posterior insular cortex lesion, even though the mechanical allody

204 In the present experiment, insular cortex-lesioned (ICX) rats showed normal respons

205 Patients with focal anterior insular cortex lesions displayed decreased discriminatio

206 In contrast, patients with insular cortex lesions failed to adjust their bets by th

207 findings reveal that only discrete anterior insular cortex lesions, but not anterior cingulate corte

208 Volume reduction in insular cortex may constitute an important neuropatholog

209 stable lesions to the vmPFC (n = 20) and the insular cortex (n = 13) were compared against healthy su

210 We observed patterns of fMRI activity within insular cortex narrowly tuned to specific tastants consi

211 Insular cortex neurons demonstrate food-cue-biased respo

212 d to activate limbic/paralimbic regions (eg, insular cortex, nucleus accumbens, and parahippocampal g

213 Conversely, the insular cortex of AD patients was hypogyrificated.

214 roach to monitor visual cue responses in the insular cortex of behaving mice across hunger states.

215 In the hypothalamus and granular insular cortex of mice with type 1 diabetes, bone marrow

216 analyses of the neuronal connections of the insular cortex of the macaque monkey using modern high-r

217 gulation within the right and left posterior insular cortex of the rat, suggest the possibility of tr

218 parahippocampal gyrus and frontal operculum/insular cortex of the right hemisphere and, to a lesser

219 The anterior insular cortex of the right hemisphere, in particular it

220 eral areas, including the prefrontal cortex, insular cortex, olfactory bulb, amygdala, and hippocampu

221 rease of activity was observed in the fronto-insular cortex on both hemispheres.

222 inergic projections to the rostral agranular insular cortex on GABAergic and oxytocin receptor-expres

223 lesions aimed at the gustatory region of the insular cortex on instrumental conditioning in rats.

224 lateral or bilateral electrolytic lesions of insular cortex or 'sham' operations.

225 ns whose locations matched with the anterior insular cortex or anterior cingulate cortex clusters ide

226 on of others' pain in patients with anterior insular cortex or anterior cingulate cortex lesions whos

227 ding the piriform cortex, entorhinal cortex, insular cortex, orbital cortex, and all cortical amygdal

228 n including the nucleus accumbens, striatum, insular cortex, orbitofrontal cortex, and medial forebra

229 The vmPFC and insular cortex patients showed selective and distinctive

230 nular insular (AId) and regions of posterior insular cortex (PI-comprising the agranular, dysgranular

231 choline has been evidenced in the posterior insular cortex (pIC) of neuropathic animal, which was si

232 r vestibular cortex (PIVC) and the posterior insular cortex (PIC).

233 The insular cortex plays a central role in the perception an

234 Animal and human studies suggest that the insular cortex plays an important role in subjective awa

235 in the medial and lateral frontal cortices, insular cortex, posterior cingulate cortex, precuneus, a

236 al functional connectivity with parietal and insular cortex, predicted individual variability in stra

237 ation of the secondary somatosensory cortex, insular cortex, prefrontal cortex, inferior parietal lob

238 ded the olfactory system, nucleus accumbens, insular cortex, prefrontal cortex, ventral tegmental are

239 nsory and stress areas such as somatosensory/insular cortex, preoptic area, paraventricular nucleus,

240 that acute microinfusion of MK-801 into the insular cortex prevented the attenuation of gustatory ne

241 ices received extensive projections from the insular cortex, primarily from its agranular areas.

242 Dysgranular anterior insular cortex projected to lateral agranular frontal co

243 nd they suggest that discrete modules within insular cortex provide the basis for its polymodal integ

244 The rostral agranular insular cortex (RAIC) has recently been identified as a

245 The rostral agranular insular cortex (RAIC) is a relevant structure in nocicep

246 The rostral agranular insular cortex (RAIC) of rats has opioid receptors and h

247 by painful stimuli is the rostral agranular insular cortex (RAIC) where, as in other parts of the co

248 inhibitor GBR-12935 in the rostral agranular insular cortex (RAIC), a cortical area that receives a d

249 touch, but evidence suggests involvement of insular cortex rather than parietal somatosensory cortic

250 In contrast, bilateral insular cortex responded to pain stimulation regardless

251 Finally, in Experiment 3, lesions of the insular cortex retarded CTA acquisition but had no influ

252 approximately 20% less c-fos ir-cells in the insular cortex, retrosplenial cortex, and dentate gyrus.

253 a third network comprising the right fronto-insular cortex (rFIC) and anterior cingulate cortex (ACC

254 The right fronto-insular cortex (rFIC) is a critical component of a salie

255 The major targets are granular insular cortex, secondary somatosensory cortex and sever

256 an unanticipated long-lasting activation of insular cortex signal transduction cascades in novel tas

257 The insular cortex subserves visceral-emotional functions, i

258 al component of the functional topography of insular cortex; such an approach could have general appl

259 alimbic areas such as anterior cingulate and insular cortex, supplementary motor area (SMA) and parie

260 , bilateral lesions to a region of posterior insular cortex, termed the "sensory insula," prevented t

261 fic VMpo projection area in dorsal posterior insular cortex that provides the basis for a somatotopic

262 neuronal populations in the dorsal anterior insular cortex that showed task-evoked activations corre

263 poro-occipital, inferior parietal, and right insular cortex that were distinctively predictive of def

264 ons, within the same neuronal populations of insular cortex, that emerged intermittently during a wak

265 he endopiriform nucleus and claustrum of the insular cortex, the globus pallidus, the ventromedial hy

266 reward and emotion encompassing the anterior insular cortex, the nucleus accumbens, and the amygdala.

267 lum together with the anterior and posterior insular cortex, the putamen, as well as subcortical whit

268 fferences in the extent of the damage to the insular cortex, three findings were common to both indiv

269 ptic glutamatergic projections from anterior insular cortex to central amygdala is critical to relaps

270 The contribution of insular cortex to speech production remains unclear and

271 ardiac nervous system, from the level of the insular cortex to the intrinsic cardiac nervous system,

272 , we implicate projections from the anterior insular cortex to the nucleus accumbens as modulating hi

273 ected pathway extending bilaterally from the insular cortex to the prefrontal cortex.

274 pendent on glutamatergic transmission in the insular cortex, to investigate the behavioral and cellul

275 We identified the anterior insular cortex-to-central amygdala projection as a new a

276 n the ventromedial prefrontal cortex and the insular cortex, two regions that have been shown to be r

277 Finally, we show that inhibition of the insular cortex using GABA agonists impairs performance o

278 e studied the auditory thalamic input to the insular cortex using mice as a model system.

279 in the amygdala, frontal operculum-anterior insular cortex, ventromedial prefrontal cortex, and the

280 tions uncover a pathway from AgRP neurons to insular cortex via the paraventricular thalamus and baso

281 A decrease in the gyrification of the insular cortex was also found in older HC participants a

282 The prefrontal and insular cortex was evaluated microscopically for overlap

283 mu-OR binding in the left insular cortex was less in bulimic subjects than in cont

284 pression in both nucleus accumbens shell and insular cortex was positively associated with risk-takin

285 r performance for both the angular gyrus and insular cortex was reliably enhanced by the addition of

286 using high-resolution fMRI revealed that the insular cortex was sensitive to both visible and invisib

287 Furthermore, fALFF in the left insular cortex was significantly positively correlated w

288 wever, an increased degree of folding of the insular cortex was specifically associated with better m

289 The ipsilateral insular cortex was stimulated both electrically (0.5 mA,

290 in Mandarin lexical tones, the left anterior insular cortex was the most active.

291 e bilateral superior parietal lobes and left insular cortex were less activated.

292 taste-related informational content in human insular cortex, which contains primary gustatory cortex.

293 greater connectivity between the DMN and the insular cortex, which is a brain region known to process

294 The insular cortex, which receives sensory inputs from both

295 aze duration (nucleus accumbens and anterior insular cortex), while two components were positively co

296 rkers of myeloarchitectural integrity of the insular cortex, while affective empathy was predicted by

297 albindin neurons in layer II of the Anterior Insular Cortex, while deep hypothermia reversed this eff

298 nd other areas of the frontal cortex and the insular cortex with hypothalamic, ventral, and dorsal st

299 sentation of sensorimotor information in the insular cortex, with possible involvement of limbic area

300 ucture enclosed between the striatum and the insular cortex, with widespread reciprocal connections w