ライフサイエンスコーパス: integrin alpha6

1 we developed a platelet-specific knockout of integrin alpha6.

2 membrane pemphigoid and mAb GoH3 and BQ16 to integrin alpha6.

3 tes with the down-regulation of cell surface integrin alpha6.

4 ression of the neuronal pathfinding molecule integrin alpha6.

5 4 (a water channel in astrocyte endfeet) and integrin-alpha6 (a laminin receptor), are upregulated in

6 This process entirely depends on integrin alpha6, a receptor for laminin.

7 in luminal cells that express keratin 14 and integrin-alpha6, a phenotype that is usually expressed e

8 ring the cells on membranes coated with anti-integrin alpha6 and beta1 antibodies.

9 maintained on feeders or off feeders express integrin alpha6 and beta1, which may form a laminin-spec

10 This promotion is inhibited by anti-integrin alpha6 and beta4 antibodies and by phosphatidyl

11 Overexpression of integrin alpha6 and beta4 rescues the invasion phenotype

12 9 partner protein interactions downregulates integrin alpha6 and beta4, diminishing Src activity and

13 Laminin alpha5 was recognized by T cell integrin alpha6 and is important for activation and inhi

14 e proband revealed negative staining for the integrin alpha6 and markedly reduced staining for the be

15 ch as plectin, collagen type XVII/BP180, and integrin alpha6 and ss4 chains, seen in conventional Lam

16 These data suggest integrin alpha6 and the GDNF signaling axis as new thera

17 l TACE constructs demonstrated not only that integrins alpha6 and beta1 bind to TACE via the disinteg

18 The contribution of integrins alpha6 and beta1 to differentiation of fetal e

19 pe IV collagen, type VII collagen, perlecan, integrin alpha6, and epithelial cell differentiation mar

20 In organ culture, anti-integrin alpha6 antibody and wortmannin reduce tooth ger

21 uced apoptosis, whereas those plated on anti-integrin alpha6 antibody were not.

22 Integrin alpha6 antisense-containing cell clones exhibit

23 gment E8, and dependence of this response on integrin alpha6 beta1 and at least one other long arm-bi

24 ls were a subset of the previously described integrin alpha6(+)CD34(+) bulge cell population, and 28.

25 enhanced expression of CD90, c-Kit (CD117), integrin alpha6 (CD49f), and CXCR4 (CD184).

26 The p67 LBP+ T cells also express the integrin alpha6 chain (CD49f), which is known to associa

27 s, suggesting that the formation of the CD82-integrin alpha6 complex reduces alpha6 integrin cell sur

28 h as CD9, CD81, and CD151 did not block this integrin alpha6-dependent morphogenesis.

29 Activating integrin alpha6-FAK pathway increases STAT3 activity, TE

30 Moreover, targeting STAT3 disrupts integrin alpha6-FAK signaling and inhibits TET3(+) GSC m

31 Integrin alpha6 has been implicated in minimal residual

32 All sera bound to integrin alpha6 in DU145 cell lysate by immunoprecipitat

33 xpected, CD82 physically associated with the integrin alpha6 in Du145-CD82 transfectant cells, sugges

34 and 5hmC accumulation also co-segregate with integrin alpha6 in patient malignant glioma.

35 ment significantly reduced the expression of integrin alpha6, integrin beta4, Fak, paxillin, Rac1/2/3

36 aminin receptors, including integrin-alpha3, integrin-alpha6, integrin-alpha7, integrin-beta1, integr

37 st therapeutic interventions to inhibit CCN1-integrin alpha6 interactions to sensitize gliomas to vir

38 Finally, the internalization of cell surface integrin alpha6 is significantly enhanced upon CD82 expr

39 An SNP near integrin alpha6 (ITGA6) reached genome-wide significance

40 sing cytokeratin15 (KRT15), CD200, CD34, and integrin, alpha6 (ITGA6) were quantitated via flow cytom

41 evels of an alternatively spliced isoform of integrin-alpha6 (ITGA6), which is associated with worse

42 reshly isolated club cells express Sca-1 and integrin alpha6, markers commonly used to characterize l

43 )-dependent hepatocyte proliferation through integrin alpha6-mediated accumulation of reactive oxygen

44 a peptide within the extracellular domain of integrin alpha6 molecule, to which Abs in the sera from

45 Blocking AR, integrin alpha6, NF-kappaB, or Bcl-xL concurrent with in

46 Unlike Integrin-alpha6(+) or c-Kit(+) cells, E-Cad/Lgr6(+) sing

47 We find that integrin alpha6 participates in this pathway, but either

48 he fluorescently labeled proteins identified integrin alpha6 precursor as a protein associated in a c

49 The identification of integrin alpha6 precursor was confirmed by Western blot

50 While integrin alpha6 promotes survival and is a direct transc

51 our results indicate that 1) CD82 attenuates integrin alpha6 signaling during a cellular morphogenic

52 Thus, ECM- integrin alpha6-STAT3-TET3 axis regulates hydroxymethyla

53 The integrin alpha6 subunit mediates an attachment of the ce

54 Control sera did not bind to the full-length integrin alpha6 subunit nor any of the cloned fragments.

55 the binding of OP autoantibodies within the integrin alpha6 subunit, by cloning four overlapping fra

56 tein complex is required in conjunction with integrin alpha6 to reduce muscle degeneration.

57 s; and 3) the accelerated internalization of integrin alpha6 upon CD82 expression correlates with the

58 Here we report that ECM through laminin-integrin alpha6 upregulates ten-eleven translocation enz

59 hEpiSC-rich integrin-alpha6(+ve) hERM cells derived by fluorometry c

60 t the lateral membrane, and beta-catenin and integrin alpha6 were located at the basolateral membrane