ライフサイエンスコーパス: intercellular signaling

1 llular matrix components and disrupting host intercellular signaling.

2 an be implemented through cell autonomous or intercellular signaling.

3 ansport lipophilic cargos and participate in intercellular signaling.

4 for membrane structure as well as intra- and intercellular signaling.

5 g higher cognition must rely on a network of intercellular signaling.

6 ells and this distribution can be induced by intercellular signaling.

7 in the generation of a bystander signal and intercellular signaling.

8 ation, primary cilia are key participants in intercellular signaling.

9 which might mediate potassium cycling and/or intercellular signaling.

10 ical nature of the local microenvironment in intercellular signaling.

11 integration of asymmetric cell divisions and intercellular signaling.

12 eptors required for cell-cell interaction or intercellular signaling.

13 t they also play a role in intracellular and intercellular signaling.

14 e synaptic activity and participate in brain intercellular signaling.

15 the technique has minimal (if any) impact on intercellular signaling.

16 esion molecules during synaptogenesis and in intercellular signaling.

17 nerve is a favorable system for the study of intercellular signaling.

18 es a transmembrane protein that functions in intercellular signaling.

19 pendence of oral-aboral ectoderm polarity on intercellular signaling.

20 sess the requirements of individual genes in intercellular signaling.

21 shing that the lin-36 pathway is involved in intercellular signaling.

22 ich in turn stimulates basal cell growth via intercellular signaling.

23 otential roles in neuronal cell adhesion and intercellular signaling.

24 y subcellular processes and in long distance intercellular signaling.

25 cally evaluate the nature and limitations of intercellular signaling.

26 liferation of basal keratinocytes likely via intercellular signaling.

27 transcriptional regulator, LAG-1, to mediate intercellular signaling.

28 rdiomyocyte GC1-dependence of the identified intercellular signaling.

29 , glutamate likely encodes multiple forms of intercellular signaling.

30 Neuronal morphogenesis relies on intercellular signaling.

31 ate metabolites vital for interorganelle and intercellular signaling.

32 ATP and other cellular metabolites for local intercellular signaling.

33 zing radiation as a result of perturbing the intercellular signaling.

34 t the extracellular environment and modulate intercellular signaling.

35 d intraflagellar transport (IFT) to organize intercellular signaling.

36 em of small molecules to communicate through intercellular signaling.

37 on of connexin binding partners and sites of intercellular signaling.

38 l migration, differentiation, apoptosis, and intercellular signaling.

39 thms of each neuron are synchronized through intercellular signaling.

40 he endodermis, suggesting the involvement of intercellular signaling.

41 as not dependent on new protein synthesis or intercellular signaling.

42 immune responses, and modified cellular and intercellular signaling.

43 he ER represents a new mode of regulation of intercellular signaling.

44 s aiming at correcting the intracellular and intercellular signaling abnormalities may prove effectiv

45 The results indicate that intercellular signaling across gap junctions is an impor

46 We propose that Dlx proteins regulate intercellular signaling across the interface between neu

47 However, the nature of intercellular signaling across the network and how indiv

48 chaperonin 60, has been established to have intercellular signaling activity in addition to its esta

49 ormation in the mouse embryo and may possess intercellular signaling activity in vivo.

50 (TME) promotes tumor development via complex intercellular signaling, aiding tumor growth and suppres

51 or release of chemical messengers to mediate intercellular signaling among human biological systems.

52 However, it remains unclear how intercellular signaling among somatic cells results in o

53 rotein signaling (RGS) proteins control both intercellular signaling and asymmetric cell divisions by

54 rane-bound NADPH oxidases necessary for both intercellular signaling and cell death.

55 regulates these cell divisions, thus linking intercellular signaling and cell polarity with the contr

56 soprenylcysteine methylation is required for intercellular signaling and development in Dictyostelium

57 tic terminals, carrying cargoes critical for intercellular signaling and disease.

58 Both intercellular signaling and engrailed expression play an

59 gulation of transcription and translation to intercellular signaling and formation of extracellular s

60 (MIF) is an atypical chemokine implicated in intercellular signaling and innate immunity.

61 protein products perform unique functions in intercellular signaling and nervous system dysfunction.

62 These cells play key roles in intercellular signaling and neuronal development, and th

63 hases (NOSs) produce nitric oxide to mediate intercellular signaling and protect against pathogens.

64 cell types in the kidney may participate in intercellular signaling and provide an enriched source o

65 tinct microdomains distinguished by specific intercellular signaling and transcriptional gradients.

66 much published literature has described the intercellular signaling and transcriptional regulators i

67 s members of gap junctions, are important in intercellular signaling and wound repair.

68 syndecan-CASK interaction may be involved in intercellular signaling and/or cell adhesion.

69 protein composition of the plasma membrane, intercellular signaling, and cell polarity.

70 ntal programs, day/night organismal changes, intercellular signaling, and proliferative safeguards.

71 sed complex pathways that linked metabolism, intercellular signaling, and stress responses to environ

72 al root positioning and the implications for intercellular signaling are considered.

73 Thus, TWEAK and Fn14 represent an intercellular signaling axis through which microglia sha

74 study tested the hypothesis that cooperative intercellular signaling between activated T cells and AS

75 ons demonstrate that EVs are involved in the intercellular signaling between airway basal cells and t

76 Net-1-mAb inhibited intercellular signaling between CAF and cancer cells by

77 mechanical interactions and/or unidentified intercellular signaling between constricted airways, the

78 Altered intercellular signaling between enteric glia and neurons

79 suggesting a role of activated NF-kappa B in intercellular signaling between epithelial and stromal c

80 Moreover, we identified the top 25 altered intercellular signaling between glial cells and neurons,

81 dentify TFF2 as a novel factor that mediates intercellular signaling between hepatocytes and HSCs and

82 Our study suggests that intercellular signaling between keratinocytes through cy

83 at SED1 contributes, at least partly, to the intercellular signaling between luminal and myoepithelia

84 of synapse formation is supported by complex intercellular signaling between potential presynaptic an

85 cules connect cells into tissues and mediate intercellular signaling between these cells.

86 Investigation of intercellular signaling between these two tumor populati

87 t neighboring structures and are integral to intercellular signaling, but are poorly defined morpholo

88 pment requires N-glycosylation regulation of intercellular signaling, but the requirements in synapto

89 These results suggest that intercellular signaling by a subset of vertebrate Wnts i

90 Intercellular signaling by a subset of Wnts is mediated

91 Intercellular signaling by bone morphogenetic proteins (

92 ients that characterize the spatial range of intercellular signaling by diffusing ligands.

93 Intercellular signaling by fibroblast growth factors pla

94 Cx37 supports transmembrane and intercellular signaling by forming functional hemichanne

95 ivo may effectively and efficiently modulate intercellular signaling by inositol phosphates.

96 ms are endowed with rapid chemosensation and intercellular signaling by ligand-gated ion channels (LG

97 Intercellular signaling by transforming growth factor-be

98 LINGO-1-mediated inhibition of OPCs through intercellular signaling by using a surface-bound LINGO-1

99 This modulation of intercellular signaling by Vj can play a crucial role in

100 The Wnt pathway is a key intercellular signaling cascade that regulates developme

101 The remarkable conservation of this intercellular signaling cascade throughout metazoan line

102 dination; however, mechanistic links between intercellular signaling, cell polarity, and cellular org

103 e of small molecule and protein mediators of intercellular signaling, chemotaxis, vasoconstriction, a

104 isabled-1 protein in mouse is known to be an intercellular signaling component of the Reelin molecula

105 ditis elegans vulva serves as a paradigm for intercellular signaling during animal development.

106 findings that highlight novel mechanisms in intercellular signaling during development.

107 ially targetable driver of hypoxia-dependent intercellular signaling during tumor development.

108 on between HH and XCI and support a role for intercellular signaling during XCI.

109 Intercellular signaling dynamics critically influence th

110 ts provide important unique insight into the intercellular signaling environment necessary for in viv

111 nderstanding of the regulatory mechanisms of intercellular signaling events that coordinate cell fate

112 s in epithelial morphogenesis and regulating intercellular signaling events.

113 nducing signals from the mesoderm and to the intercellular signaling factor noggin.

114 ecreted antagonists regulate the activity of intercellular signaling factors, thereby modulating cell

115 Important contributions come from intercellular signaling, fibroblast transformation, remo

116 Organ size is regulated by intercellular signaling for cell growth and proliferatio

117 d measurements highlight the crucial role of intercellular signaling for generating regulated spatial

118 ling involves transformation of fibroblasts; intercellular signaling-for example between epithelial a

119 g the possibility that dachsous affected the intercellular signaling function of frizzled.

120 ell contact to facilitate their own evolving intercellular signaling functions.

121 rs, including its target gene Patched (Ptc), intercellular signaling genes Bone Morphogenetic Protein

122 acellular regions (ECRs) that likely mediate intercellular signaling; however, the precise roles of E

123 lly and display diverse functions, including intercellular signaling, immunomodulation, protein matur

124 e of effects on gene expression dependent on intercellular signaling, implicating the method of bioch

125 Furthermore, we infer metabolite-driven intercellular signaling in acute kidney injury using spa

126 and uniformly all the changes resulting from intercellular signaling in both DC-->T cell and T cell--

127 Here, we uncover a novel role for Ephrin-Eph intercellular signaling in controlling mitotic spindle a

128 (AP3) gene has distinct roles in regulating intercellular signaling in different tissues.

129 Despite this, the global landscape of intercellular signaling in mammalian liver has not been

130 r vesicles (EVs) that play a central role in intercellular signaling in mammals by transporting prote

131 y have played a role in the establishment of intercellular signaling in metazoans.

132 in protein trafficking and intracellular and intercellular signaling in neuronal and non-neuronal cel

133 ation of release generates new insights into intercellular signaling in the brain.

134 of transmitter-laden vesicles enables rapid intercellular signaling in the central nervous system an

135 y projecting MNs, revealing a novel role for intercellular signaling in the establishment of neuronal

136 reveal a paracrine role for secreted cAMP in intercellular signaling in the myocardium, and we postul

137 recapitulate the tissue microenvironment and intercellular signaling in vitro.

138 interactions are compatible with a model for intercellular signaling in which the PirB extracellular

139 plays an important role in immune responses, intercellular signaling, inflammation and host-pathogen

140 ated partly by tissue-specific and partly by intercellular signaling initiated by phyA.

141 oring whether extracellular vesicles mediate intercellular signaling inside the nephron and between t

142 n of VPC fates is controlled by a network of intercellular signaling, intracellular signal transducti

143 Intercellular signaling is an essential layer of systemi

144 Intercellular signaling is critical for many FR-HIR indu

145 Intercellular signaling is critical for the normal devel

146 f ~24 h rhythms in behavior in mice in which intercellular signaling is disrupted through loss of VIP

147 Evidence suggesting an important role for intercellular signaling is emphasized.

148 Intercellular signaling is essential for the coordinatio

149 Intercellular signaling is important for accurate circad

150 Intercellular signaling is particularly critical in plan

151 We show that intercellular signaling is required for the correct patt

152 e is the key transcriptional motivator of an intercellular signaling loop which drives endomesoderm s

153 aling pathway is an evolutionarily conserved intercellular signaling mechanism essential for embryoni

154 ling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper e

155 The Notch signaling pathway is a conserved intercellular signaling mechanism that is essential for

156 Notch signaling is an ancient intercellular signaling mechanism that plays myriad role

157 led growth of neighboring neurons through an intercellular signaling mechanism that requires its glyc

158 e of [H(+)] buildup limits the speed of this intercellular signaling mechanism, but for tonic signals

159 re components of an evolutionarily conserved intercellular signaling mechanism.

160 Further studies on intracellular and intercellular signaling mechanisms modulating multinucle

161 in the female reproductive tract depends on intercellular signaling mechanisms that coordinate sperm

162 HSL quorum sensing has become a paradigm for intercellular signaling mechanisms.

163 control heterocyst pattern formation through intercellular signaling mechanisms.

164 ance of instructions from the egg; or mutual intercellular signaling mediated by cell contact or diff

165 The intercellular signaling mediated by endothelins and thei

166 Intercellular signaling mediated by evolutionarily conse

167 ostimulatory molecules, and this cooperative intercellular signaling mediates the induction of proast

168 re, ATP rather than Ca or IP3 is the primary intercellular signaling messenger.

169 t that the EBV-encoded dUTPase may act as an intercellular signaling molecule capable of modulating t

170 e action of gamma-aminobutyrate (GABA) as an intercellular signaling molecule has been intensively st

171 likely reflects the importance of ATP as an intercellular signaling molecule in this system.

172 rotein that has been shown to function as an intercellular signaling molecule that can promote the mo

173 We suggest that norspermidine serves as an intercellular signaling molecule that mediates the attac

174 ne lactone, an acyl-homoserine lactone (AHL) intercellular signaling molecule used by many gram-negat

175 Intercellular signaling molecules and their receptors, w

176 veral members of the WNT family of paracrine intercellular signaling molecules are expressed in speci

177 A large number of intercellular signaling molecules have been identified t

178 xin 1 (PANX1) ion channels causes release of intercellular signaling molecules in a variety of (patho

179 Endocannabinoids are key intercellular signaling molecules in the brain, but the

180 Neuropeptides, as pervasive intercellular signaling molecules in the CNS, modulate a

181 ns constitute one of the largest families of intercellular signaling molecules in vertebrates with es

182 s) and their receptors (Fgfrs) are important intercellular signaling molecules that are essential to

183 a new role for Eph receptors and Ephrins as intercellular signaling molecules that establish cell po

184 ic amines such as serotonin and dopamine are intercellular signaling molecules that function widely a

185 animal tissues depends upon highly conserved intercellular signaling molecules that include the secre

186 One of the intercellular signaling molecules that is involved in th

187 Hedgehogs (Hhs) are intercellular signaling molecules that regulate tissue p

188 omoserine lactones (acyl-HSLs) are important intercellular signaling molecules used by many bacteria

189 Further investigation of these critical intercellular signaling molecules will provide important

190 pigments involve the opposing effects of two intercellular signaling molecules, alpha-melanocyte stim

191 eomelanin involve the opposing action of two intercellular signaling molecules, alpha-melanocyte-stim

192 idic acid (LPA) are now recognized widely as intercellular signaling molecules, the medicinal chemist

193 t use N-acyl-l-homoserine lactones (AHLs) as intercellular signaling molecules.

194 on may involve interplay of EphA4 with other intercellular signaling molecules.

195 ly synthesized, physiologically significant, intercellular signaling molecules.

196 activity that are also known to function as intercellular signaling molecules.

197 environment in silico as characterized by an intercellular signaling network comprising 5 types of ce

198 The intercellular signaling network underlying Caenorhabditi

199 array of soluble factors, forming a complex intercellular signaling network.

200 lular adaptations at the level of long-range intercellular signaling networks in the unborn fetus.

201 standing of the integrated intracellular and intercellular signaling networks that control plant grow

202 developmental precision is achieved through intercellular signaling networks, which establish patter

203 AD nuclei, as well as subsequent analysis of intercellular signaling networks.

204 challenges through complex intracellular and intercellular signaling networks.

205 However, the intercellular signaling niches necessary for hDPSC survi

206 ndamental mechanism by which neurons control intercellular signaling, nutrient uptake, and synaptic t

207 thway suggests that previously unappreciated intercellular signaling occurs during myogenic different

208 me characteristics mediate hypoxia-dependent intercellular signaling of the highly malignant brain tu

209 lpha5 function plays an integral role in the intercellular signaling of this stage of development.

210 It is unclear whether EVs promote intercellular signaling or serve primarily to dispose of

211 Bacteria use intercellular signaling, or quorum sensing (QS), to shar

212 there is a hemichannel-mediated, purinergic intercellular signaling pathway between supporting cells

213 Genetic and biochemical studies revealed an intercellular signaling pathway in which intestinal or h

214 The Notch intercellular signaling pathway mediates the specificati

215 rstood, but there is evidence that the Notch intercellular signaling pathway plays a critical role.

216 The Notch intercellular signaling pathway regulates cell fate dete

217 and discs overgrown (dco) function within an intercellular signaling pathway that controls growth and

218 as ligand and receptor, respectively, for an intercellular signaling pathway that influences tissue p

219 are upstream components of a wound-induced, intercellular signaling pathway that involves both the b

220 as ligand and receptor, respectively, for an intercellular signaling pathway that regulates Hippo sig

221 ged1 ( JAG1 ), a conserved gene of the Notch intercellular signaling pathway, have been found to caus

222 our-jointed, Dachsous and Fat function in an intercellular signaling pathway, identify a normal role

223 JAG1 encodes a ligand in the Notch intercellular signaling pathway.

224 lying cell fate specification and elucidated intercellular signaling pathways [1].

225 Many niches and their intercellular signaling pathways are known, but for the

226 xtracellular proteins that play key roles in intercellular signaling pathways during vertebrate embry

227 Meristems require a myriad of intercellular signaling pathways for coordination of cel

228 Our objective is to dissect intercellular signaling pathways from neurons to glial p

229 sely investigated, with many of the critical intercellular signaling pathways identified, and well ch

230 ling pathway is one of several key conserved intercellular signaling pathways in animals, and plays f

231 rleukin 6 (IL-6) and its receptor (IL-6R) in intercellular signaling pathways in the olfactory mucosa

232 A handful of core intercellular signaling pathways play pivotal roles in a

233 However, the intercellular signaling pathways that direct the synchro

234 critical roles in these circuits, and common intercellular signaling pathways that link diverse genes

235 The results presented have implications for intercellular signaling pathways that regulate embryonic

236 g requires the precise interplay of numerous intercellular signaling pathways to ensure that cells ar

237 cts, also observed in vivo, involve multiple intercellular signaling pathways, engaging Hmga2.

238 dest and most functionally diverse of animal intercellular signaling pathways.

239 and imaginal development depends on the same intercellular signaling pathways.

240 inductions act via evolutionarily conserved intercellular signaling pathways.

241 of multiple cell types, via both intra- and intercellular signaling pathways.

242 pression in proliferation, cytotoxicity, and intercellular signaling pathways.

243 ful transcriptional profile and enhanced key intercellular signaling pathways.

244 ions are maintained by intricate networks of intercellular signaling pathways.

245 oteoglycans with regulatory roles in several intercellular signaling pathways.

246 3/ESR-related peptide family, participate in intercellular-signaling pathways.

247 ready contain the element is inhibited by an intercellular signaling peptide encoded by ICEBs1.

248 Downstream of intercellular signaling, pre- and postsynaptic scaffolds

249 hat the mybC gene product is required for an intercellular signaling process controlling maturation o

250 Organismal proteostasis is maintained by intercellular signaling processes including cell nonauto

251 egulated exocytosis forms the basis for many intercellular signaling processes, for example, in hormo

252 ontrolling a wide array of developmental and intercellular signaling processes.

253 ne, is a cell-surface associated short-range intercellular signaling protein in Myxococcus xanthus.

254 C factor, an intercellular signaling protein, is required for aggrega

255 The hedgehog (Hh) family of intercellular signaling proteins is intricately linked t

256 The semaphorins are a family of intercellular signaling proteins that has grown to inclu

257 urrogates to investigate this superfamily of intercellular signaling proteins.

258 neral features for biochemical regulation of intercellular signaling: receptors are less frequent tar

259 ng a dynamic and tunable level of intra- and intercellular signaling regulation.

260 However, inferring metabolite-mediated intercellular signaling remains challenging, partially d

261 ronment, but how biomechanics contributes to intercellular signaling remains unclear.

262 tuent that is believed to serve an important intercellular signaling role at certain excitatory synap

263 scriptional regulation (NF-kappaB, Gli), and intercellular signaling (Shh) to control bulge stem cell

264 neurogenic inflammation potentially through intercellular signaling.SIGNIFICANCE STATEMENT Nocicepto

265 DD), a molecule previously shown to regulate intercellular signaling, stress surveillance [6], and de

266 y serve as the endogenous ligands of a novel intercellular signaling system found widely throughout t

267 ns in genes that antagonize the ras-mediated intercellular signaling system responsible for vulval in

268 Thus our data identify an intercellular signaling system that restricts, directly

269 S uses a previously unknown peptide-mediated intercellular signaling system to control SpeB productio

270 There are three intercellular signaling systems employed by P. aeruginos

271 istic human pathogen which relies on several intercellular signaling systems for optimum population d

272 r in flowering plants, and several different intercellular signaling systems have evolved to elicit t

273 d its VPAC2 receptor form a key component of intercellular signaling systems in the SCN and criticall

274 Intracellular- and intercellular-signaling systems transduce this informati

275 However, the intercellular signaling that drives these processes rema

276 (DA) in midbrain represents a novel form of intercellular signaling that inherently differs from cla

277 bodies, such as cell growth, migration, and intercellular signaling, that are required for primitive

278 Nitric oxide (NO) mediates intercellular signaling through activation of its recept

279 ant on cell surface proteoglycans, regulates intercellular signaling through its binding to various g

280 ing pathways, and the ability to investigate intercellular signaling through studies of cells remaini

281 Intercellular signaling through the Notch receptor and i

282 ellular addresses at specific times, and use intercellular signaling to coordinate multicellular even

283 Small extracellular vesicles (sEVs) mediate intercellular signaling to coordinate the proliferation

284 ection reshapes the microenvironment through intercellular signaling to facilitate spread and how spa

285 tial consequences for processes ranging from intercellular signaling to large-scale phytoplankton dyn

286 cell subpopulations engage in bidirectional intercellular signaling to regulate the expression of di

287 at retinal precursors utilize Notch-mediated intercellular signaling to regulate their fates.

288 ain an intracellular molecular clock and use intercellular signaling to synchronize their timekeeping

289 volvement, and in particular the blocking of intercellular signaling transduction between neuron and

290 production of antibiotics, are controlled by intercellular signaling using small molecules.

291 Intercellular signaling via extracellular vesicles (EVs)

292 and of their Sfrp inhibitors, together with intercellular signaling via PCP proteins, polarize node

293 ptimum offer a physical basis for intra- and intercellular signaling via sound waves at interfaces, w

294 Intercellular signaling was initiated by pN-level forces

295 expression of neuropeptides critical for SCN intercellular signaling was significantly disturbed.

296 To elucidate the mechanism controlling this intercellular signaling, we tested the role of the Wnt/b

297 and electrophysiology with intracellular and intercellular signaling, we were able to develop the fir

298 -resistance transfer through manipulation of intercellular signaling, with implications in the clinic

299 hieved light-controlled molecular mapping of intercellular signaling within functional immune synapse

300 Defective intercellular signaling within peripheral nerves might u