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1 effect is mediated in large part by the gene interferon regulatory factor 1.
2 r a key member of the IFN signaling pathway, interferon regulatory factor 1.
3 f the bona fide endogenous STAT1 target gene interferon regulatory factor 1.
4 nitric oxide synthase, interferon-gamma, and interferon regulatory factor 1.
5 lations: death-associated protein kinase and interferon regulatory factor 1.
6 cking the proapoptotic transcription factor, interferon regulatory factor-1.
7 for the interferon (IFN)-regulated proteins interferon regulatory factor 1, 2',5'-oligoadenylate syn
8 from mice lacking the IFN-gamma receptor or interferon regulatory factor 1, a transcription factor e
9 rther supported by the reduced expression of interferon regulatory factor 1, a well-known NF-kappa B
10 saccharide-induced nuclear factor-kappaB and interferon regulatory factor-1 activation in RAW 264.7 m
11 immunity to dietary antigen was dependent on interferon regulatory factor 1 and dissociated from supp
12 hat VZV infection inhibited transcription of interferon regulatory factor 1 and the MHC class II tran
13 inding activity for the transcription factor interferon regulatory factor-1 and in Fas mRNA induction
15 ediated by two transcription factors, IRF-1 (interferon-regulatory factor-1) and ICSBP (interferon-co
16 ases (TKT, Eck, HEK), transcription factors (interferon regulatory factor-1), and HLA class I were th
17 nscriptional activator proteins (ATF2/c-JUN, interferon regulatory factor 1, and p50/p65 of NF-kappaB
18 re low for interleukin (IL)-2 receptor-beta, interferon regulatory factor-1, and signal transducer an
19 analyses demonstrate that neither CIITA nor interferon regulatory factor 1 are upregulated in infect
20 curs include an increase in the synthesis of interferon regulatory factor-1 as well as a nuclear fact
22 tor-1 expression was associated with loss of interferon regulatory factor-1 binding to the interferon
23 rafficking and macrophage recruitment (e.g., interferon regulatory factor 1, CD97), adaptive immune r
24 wing transfection of wild type Stat1alpha or interferon regulatory factor 1 cDNA into cells lacking t
25 in macrophages as well as their virulence in interferon regulatory factor 1-deficient (IRF-1(-/-)) mi
26 BMEI1090-BMEI1091 mutants were attenuated in interferon regulatory factor 1-deficient (IRF-1(-/-)) mi
28 y, on p28 gene transcription in a c-Rel- and interferon regulatory factor 1-dependent manner, respect
29 study, we determined that the generation of interferon regulatory factor-1 expression in human derma
33 is factor-alpha and interferon-gamma-induced interferon regulatory factor-1 gene transcription, as as
36 nced retroelements and synergized with IRF1 (interferon regulatory factor 1) in the activation of IFN
37 nitric oxide synthase and cyclooxygenase-2, interferon regulatory factor-1, interferon-inducible pro
38 on and was associated with downregulation of interferon regulatory factor 1 (IRF-1) and decreased lev
39 ion and activity of the transcription factor interferon regulatory factor 1 (IRF-1) and expression of
41 ion is associated with reduced expression of interferon regulatory factor 1 (IRF-1) and PU.1 in nucle
42 ving inhibition of the transcription factors interferon regulatory factor 1 (IRF-1) and upstream stim
43 ion of type I interferon (IFN) signaling and interferon regulatory factor 1 (IRF-1) expression is req
44 d the gene encoding the transcription factor interferon regulatory factor 1 (IRF-1) for further analy
45 iation between JIA and a polymorphism in the interferon regulatory factor 1 (IRF-1) gene has previous
49 ion and joint-associated swelling.IMPORTANCE Interferon regulatory factor 1 (IRF-1) is a transcriptio
53 Here we report that the transcription factor interferon regulatory factor 1 (IRF-1) is required for c
54 bryo fibroblasts derived from Pkr(o/o) mice, interferon regulatory factor 1 (IRF-1) or guanylate bind
55 inhibited TNF alpha- and IFN gamma-mediated interferon regulatory factor 1 (IRF-1) protein expressio
56 ession of the antiviral and tumor suppressor interferon regulatory factor 1 (IRF-1) selectively atten
57 al deficiency of antiviral tumor-suppressive interferon regulatory factor 1 (IRF-1) selectively promo
58 growth factor beta (TGF-beta) signaling, and interferon regulatory factor 1 (IRF-1) transactivation.
60 changes at putative binding sites for STAT1, interferon regulatory factor 1 (IRF-1), and E-box protei
61 eactive with the transcription factors PU.1, interferon regulatory factor 1 (IRF-1), and interferon c
62 observed that CAF induced the expression of interferon regulatory factor 1 (IRF-1), and that IRF-1 g
64 g vascular cell adhesion protein 1 (VCAM-1), interferon regulatory factor 1 (IRF-1), mitochondrial hy
66 Therefore, we examined the expression of interferon regulatory factor 1 (IRF-1), which plays an i
69 tory factor (IRF) family members, especially interferon regulatory factor-1 (IRF-1) and interferon re
71 omoter analysis of CARD4/NOD1 indicates that interferon regulatory factor-1 (IRF-1) binding motif (-7
72 ion of not only growth-related genes such as interferon regulatory factor-1 (IRF-1) but also differen
73 ddition, the TATA-less promoter of the human interferon regulatory factor-1 (IRF-1) gene contains a D
80 nd activator of transcription 1 (STAT1), and interferon regulatory factor-1 (IRF-1) often mediate the
82 ational processes involved in regulating the interferon regulatory factor-1 (IRF-1) tumor suppressor
85 ously demonstrated that global deficiency of Interferon Regulatory Factor-1 (IRF-1), a classically an
86 y SNP (-1623A/G) modified a binding site for interferon regulatory factor-1 (IRF-1), a major interfer
87 stically induce expression of mRNAs encoding interferon regulatory factor-1 (IRF-1), intercellular ad
90 lost its transient nature in the absence of interferon-regulatory factor 1 (IRF-1), a transcription
91 This report demonstrates that expression of interferon-regulatory factor 1 (IRF-1), also known as in
93 not affect the ability of IFN-gamma-induced interferon-regulatory factor-1 (IRF-1) to bind the IRF-1
95 alpha1 [IFNA1], interferon-gamma [IFNG], and interferon regulatory factor 1 [IRF-1]) were investigate
96 iation constant of the DNA binding domain of interferon regulatory factor 1 (IRF1 DBD) for its DNA bi
97 of viral double-stranded RNA, depends on the interferon regulatory factor 1 (IRF1) and IRF2 transcrip
99 b which has full enhancer activity and binds interferon regulatory factor 1 (IRF1) and nuclear factor
100 2/GAS) elements in the LMP2 promoter bind to interferon regulatory factor 1 (IRF1) and Stat1 and are
101 ransitioned cells are defective in inducible interferon regulatory factor 1 (IRF1) expression by occl
102 association in European Americans was at the interferon regulatory factor 1 (IRF1) locus on 5q31.1.
105 ow that CITED2 deficiency elevates STAT1 and interferon regulatory factor 1 (IRF1) regulated pro-infl
108 repeat domain containing 7 (FBXW7)-regulated interferon regulatory factor 1 (IRF1) ubiquitination deg
110 signaling can also induce the expression of interferon regulatory factor 1 (IRF1), an important mole
111 ed in the 5'-end of the STAT1-dependent gene interferon regulatory factor 1 (IRF1), but the role of t
112 ding IFN alpha and beta receptor 1 (IFNAR1), interferon regulatory factor 1 (IRF1), IRF9, and STAT1 e
113 is highly dynamic at the STAT1 target gene, interferon regulatory factor 1 (IRF1), suggesting that a
114 on was regulated by interferon-dependent and interferon regulatory factor 1 (IRF1)-dependent pathways
120 associated with antigen processing-1 (TAP1), interferon regulatory factor-1 (IRF1), and class I major
121 ism by HCV NS5A, leading to activation of an interferon regulatory factor-1 (IRF1)-driven cell intrin
128 ry factor-1 protein and the up-regulation of interferon regulatory factor-1 mRNA levels was inhibited
129 t essential, however, for the association of interferon regulatory factor-1 mRNA with polyribosomes,
130 These candidate genes include NFkappaB, interferon regulatory factor-1, nucleophosmin, and the X
131 nges in a novel signaling pathway, involving interferon regulatory factor-1, nucleophosmin, NFkappaB,
133 and downregulates expression of proapoptotic interferon regulatory factor-1 protein and suppressor of
135 somes, suggesting iron was not essential for interferon regulatory factor-1 protein translation.
137 e and increased the nuclear translocation of interferon-regulatory factor-1, STAT1, and STAT2 in huma
138 romoters were stimulated by the 'downstream' interferon regulatory factor 1 that, in turn, is known t
139 expression of the transcription factor IRF1 (interferon-regulatory factor 1), the roles of IRF1 in im
140 tituted mRNA induced the expression of TLR3, interferon regulatory factor-1, tumor necrosis factor-al
141 hage inflammatory protein-I (v-MIP-I), viral interferon regulatory factor-1(v-IRF-1), and viral tegum
142 man herpesvirus 8 (HHV-8) gene product viral interferon regulatory factor 1 (vIRF-1) is targeted to m
144 sarcoma-associated herpesvirus (KSHV) viral interferon regulatory factor 1 (vIRF1) interacts with th
147 The IFN-responsive transcriptional activator interferon regulatory factor-1 was also strongly induced
148 on of genes in response to IFNgamma, such as interferon regulatory factor-1, was severely impaired by
149 st, IFNgamma induced a delayed activation of interferon regulatory factor-1 without any effect on NF-