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1 of all transcription (genic, intragenic, and intergenic).
2 tein-coding genes, and the rest appear to be intergenic.
3 Ss) were annotated as noncoding, with 24% in intergenic, 12% in promoters, and 28% in introns, with s
5 ncing data from 268 patients to catalog gene-intergenic and intergenic-intergenic fusions and charact
7 e to WGS data because of the large number of intergenic and intron regions that consist of a massive
9 al variants (SVs), including those targeting intergenic and intronic non-coding regions that eluded p
11 he complete mitochondrial genome and nuclear intergenic and protein-coding sequences were obtained by
13 to identify 4 riboswitches, 13 trans-acting (intergenic), and 22 cis-acting (antisense) small RNAs (t
14 s in different regions of the genome (genic, intergenic, and heterochromatic) and at different distan
15 DNA is preferentially hypomethylated within intergenic areas and LINE1 promoter areas of the genome.
16 aralleled coverage of coding, non-coding and intergenic areas of both nuclear and mitochondrial genom
17 II are detected at gene-coding as well as at intergenic areas when double-strand breaks (DSBs) are in
20 further characterize the genomic features of intergenic cheRNA (icheRNA) and their similarity to enha
21 uterus PGR showed far more tendency to bind intergenic chromatin regions and low evidence of interac
22 dentify a novel long noncoding RNA Noncoding Intergenic Co-Induced transcript (NICI) on chromosome 12
23 n (PCR) analyses: Enterobacterial Repetitive Intergenic Consensus (ERIC) and Random Amplified Polymor
24 n HSPCs from EGF-treated mice, but increased intergenic copy number variant mutations were detected.
25 in regulatory pathway that connects aberrant intergenic CpG methylation to human neoplastic and devel
26 f methylation in the heart, enriched in lone intergenic CpGs and depleted from CpG islands around gen
27 ory linkage appears to have resulted from an intergenic deletion in eutherians that significantly alt
28 control the establishment and maintenance of intergenic DNA methylation remain poorly understood.
32 iated H3K27me3 accumulate initially at large intergenic domains that can then spread into genes only
33 as those predicted from base-pair changes in intergenic enhancer sites, coding-region variants, and S
35 400Kb upstream to IGFBP5, which overlaps an intergenic ERalpha-bound enhancer that loops to the IGFB
37 spatially and categorically; (ii) coding and intergenic features are recapitulated at high resolution
38 lucidate the potential oncogenic function of intergenic fusions and highlight the wide-ranging conseq
39 , RSPO3, and PIK3CA-can be generated by gene-intergenic fusions through splicing of the intervening r
42 lti-exonic transcripts from 561 intronic and intergenic haploblocks associated with 392 traits and di
46 268 patients to catalog gene-intergenic and intergenic-intergenic fusions and characterize their imp
48 of 54,875 bacterial genomes identified 4686 intergenic invertible DNA regions (invertons), revealing
53 an experimental reannotation of the GENCODE intergenic lncRNA populations in matched human and mouse
58 ification of these lncRNAs reveals that most intergenic lncRNAs originate from enhancers rather than
59 ic class of RNAs that includes, for example, intergenic lncRNAs, antisense transcripts, and enhancer
60 atterns, and uncovers two notable classes of intergenic lncRNAs: one showing strong purifying selecti
61 in the genome, predominantly expressed from intergenic loci, and associated with antiviral or DNA da
63 rmed on human left/right pairs identified an intergenic long noncoding RNA adjacent to the PITX2 gene
65 PRO-seq experiments identified TSSs for 480 intergenic miRNAs, indicating a wide usage of alternativ
68 ings identify Neat1 as a p53-regulated large intergenic ncRNA (lincRNA) with a key role in suppressin
71 hibit distinct messenger RNA (mRNA) and long intergenic non-coding RNA (lincRNA) profiles compared to
72 In this study, we present data that long intergenic non-coding RNA 346 (LINC00346) functions as a
74 ication and characterization of a novel long intergenic non-coding RNA with MyoD-regulated and skelet
78 ematic investigation of the capacity of long intergenic non-coding RNAs (lincRNAs) as biomarkers asso
81 atment of cancer, the interplay between long intergenic non-coding RNAs (lncRNAs) and chromatin remod
82 h increased expression of LRRK2 and two long intergenic non-coding RNAs (lncRNAs), LINC02555 and AC07
83 transcriptome to detect 6,701 putative long intergenic non-coding transcripts (lincRNAs) expressed i
84 deletion-based approach identified two long intergenic non-coding(linc)RNAs, lincRNA-Cox2 and lincRN
87 in brain expression of a human-specific long intergenic noncoding RNA (LINC01268; GRCh37/hg19: LOC285
89 tive cardiac lncRNAs, including LIPCAR (long intergenic noncoding RNA predicting cardiac remodeling a
90 the prior postmortem association of the long intergenic noncoding RNA specifically with suicide by vi
91 ong noncoding RNA (lncRNA) Flicr (Foxp3 long intergenic noncoding RNA) is a negative regulator that t
100 xtent to which alternative splicing and long intergenic noncoding RNAs (lincRNAs) contribute to the s
102 ese noncoding RNAs, a growing number of long intergenic noncoding RNAs (lincRNAs) have been described
104 e shield prevents Pol I from producing sense intergenic noncoding RNAs (sincRNAs) that can disrupt nu
106 previously unreported fusions involving long intergenic noncoding RNAs, demonstrating a previously un
110 HPRT1 function was robust to deletion of any intergenic or deeply intronic non-coding region, indicat
114 ealed that changes in gene expression due to intergenic polymorphisms are associated with longevity a
116 was recruited by the cricket paralysis virus intergenic region (CrPV IGR) IRES to form a stable 40S-I
118 some, we took advantage of the IRES from the intergenic region (IGR) of the Cricket Paralysis Virus.
119 ide (nt) deletion (Delta39) in the noncoding intergenic region (IGR) of the viral large (L) segment t
120 We have recently shown that the noncoding intergenic region (IGR) present in each arenavirus genom
122 on and a point mutation within the L-segment intergenic region (IGR), and three silent changes in the
125 RH50 binds to transcripts of the 23S-4.5S intergenic region and, in its absence, levels of the cor
128 One of these, at chromosome 11p13, is an intergenic region between Ets homologous factor (EHF) an
131 ated within a predicted super-enhancer in an intergenic region between HLA-DRB1 and HLA-DQA1, localiz
132 regions go through substantial changes: the intergenic region between NP and VP35, as well as the fi
133 pts involving parts of PPP3R1, CNRIP1 and an intergenic region between PLEK and CNRIP1, in the blood
134 Tandem repeats were frequently found in the intergenic region between the prophage at the 3' end and
135 IRES of Israeli acute paralysis virus (IAPV) intergenic region captures and redirects translating rib
136 G, NID1, DHRS12, ITPK1, ACSF3, TNFRSF13C and intergenic region chr10p12.31 was replicated in a cohort
139 ), HDL-cholesterol (PHOSPHO1, SYNGAP1 and an intergenic region in chromosome 2) and triglycerides (MY
140 single-nucleotide polymorphisms (SNPs) in an intergenic region located between the oncogenes MYC and
141 ing disruptive missense RVs of NPC1L1 and an intergenic region near APOC1P1 associated with low-densi
143 .71 x 10(-10), rs16891982), and revealed the intergenic region of BEND7 and PRPF18 as a novel locus a
147 ription start site was identified within the intergenic region of the miR-183 cluster, which may regu
149 gnificant associations at two novel loci: an intergenic region on 9p21.3 (rs12553324, P = 5.87 x 10 (
150 nflammatory states, maps to the 5' end of an intergenic region on Chr11p13 that is implicated as a mo
151 ree loci located in GABBR2, RUFY3, and in an intergenic region on chromosome 2 replicated with the sa
152 olymorphisms (SNPs) (r(2)>0.9) located in an intergenic region on chromosome 3q26 were associated wit
153 ignificant loci were identified including an intergenic region on chromosome 9 that has previously be
154 pendent reporter gene cassette located in an intergenic region remained silent, indicating that the t
155 S_NmUC isolates was an IS1301 element in the intergenic region separating the capsule ctr-css operons
156 NA genome, with an 827 nt-long 5' UTR and an intergenic region separating two open reading frames.
157 d and confirmed a one-nucleotide indel in an intergenic region that significantly alters global trans
159 gulator in Chlamydia, can bind to the trpRBA intergenic region upstream of the alternative trpBA prom
160 ontrol is mediated by binding of MarA to the intergenic region upstream of the ycgZ-ymgABC operon.
162 4.8 kb miR-183 family cluster, including the intergenic region which contains highly conserved genomi
163 We show that XdhR binds the xdhABC-xdhR intergenic region with high affinity (Kd approximately 0
164 us PecS binds two sites within the pecS-pecM intergenic region with K(d) = 0.3 +/- 0.1 nM, a binding
165 omosome reporters, we discovered that the 5' intergenic region, introns 2 and 6 of human telomerase g
166 n of a 198-nucleotide sequence into the HN-L intergenic region, resulting in reduced viral gene expre
167 We applied this methodology to the HBS1L-MYB intergenic region, which is associated with red-blood-ce
168 with a transposon insertion in the upstream intergenic region, while FT2c and FT2d obtained a transp
176 CFAP45, AFF3, TP73, UBCLP1, RPL13P, and two intergenic regions (p values < 0.0001 were confirmed usi
177 tioned rice genome showed that regulatory or intergenic regions account for the most trait heritabili
178 border regions between domains contain large intergenic regions and a high density of transcription f
181 we show that BORDER proteins are enriched in intergenic regions and prevent interference between clos
183 (rRNA) processing, many coding sequences and intergenic regions appeared to be direct targets of RNas
184 ty of identified pA sites were mapped to the intergenic regions downstream of previously annotated EB
187 transmembrane domains, and that thymine-rich intergenic regions harbor a widespread potential to prod
189 f somatic mutation across exons, introns and intergenic regions highlights the repertoire of cancer g
190 These SNPs were distributed in genic and intergenic regions in the eight pseudomolecules of the p
191 ong noncoding transcripts (>200 nt) from the intergenic regions of annotated protein-coding genes.
192 ensive transcriptional activity occurring in intergenic regions of genomes has raised the question wh
193 heory based sigma70 model indicates that the intergenic regions of salt-responsive genes are enriched
194 ensity of sigma70 promoter-like sites in the intergenic regions of salt-responsive genes drives the R
199 regulated loci correspond to transposons and intergenic regions producing 24-nucleotide siRNAs that g
200 BCG1, CPT1A, MYLIP, TXNIP and SLC7A11) and 2 intergenic regions showed differential methylation in as
201 ase on the X-chromosome, and an elevation in intergenic regions suggesting that chromatin structure m
202 cted, nucleotide diversity is much higher in intergenic regions than within gene bodies (regions span
203 ng use of an alternative genetic code, large intergenic regions that are highly expressed and up to 3
204 evising several methods to select subsets of intergenic regions that can concentrate these rare RNA c
206 icient resolution in the larger intronic and intergenic regions to identify copy number changes.
209 Stringtie was then performed to identify the intergenic regions whose expression was influenced by th
212 l coding sequences, complex genomic regions, intergenic regions, and methylation motifs revealed smal
213 bserve that the genome is more accessible in intergenic regions, and that increased accessibility is
214 introns), while being depleted in coding and intergenic regions, and these findings may have biologic
216 t may be transcribed: coding, noncoding, and intergenic regions, as well as repetitive elements, telo
217 ion in CpG island (CGI) and demethylation in intergenic regions, defined as 'backbone', largely vary
219 ften, 24-nt-dominated siRNA loci occurred in intergenic regions, especially at the 5'-flanking region
220 ociated haplotype blocks are in intronic and intergenic regions, hindering their functional evaluatio
222 nt along the telomere-centromere axis in the intergenic regions, positively correlated with the dista
223 now only sparsely documented, namely longer intergenic regions, post-horizontal gene transfer (HGT)
224 H3K27me3 mark were more abundant (> 80%) in intergenic regions, whereas DBSs for H3K4me3 were distri
225 of 6mA reveals that this mark is enriched at intergenic regions, with a preference for certain superf
245 study, we report that HOTAIR (HOX antisense intergenic RNA) is upregulated in tamoxifen-resistant br
246 lncRNA) HOTAIR (for HOX Transcript Antisense Intergenic RNA) mediates a physical interaction between
247 ithin the NANCI (Nkx2.1-associated noncoding intergenic RNA)-Nkx2.1 gene duplex that is essential for
248 s of non-coding RNA including microRNA, long intergenic RNA, small nucleolar RNA, natural antisense t
250 unique expression of coding, noncoding, and intergenic RNAs in the mature mouse brain with RNA-Seq a
251 duction near genes compared with the rest of intergenic sequences is greater in a species with larger
252 ding alternative rbcS genes and adjoining 5'-intergenic sequences revealed that Rubisco production wa
253 utative mammary-specific enhancer within the intergenic sequences separating the two Stat5 genes.
255 actor and disengagement of RNA polymerase at intergenic sequences, particularly those at the NP:P and
260 th of purifying selection operating over all intergenic sites is consistently intermediate between th
261 observed in addicted rats occurred mostly at intergenic sites located on long and short interspersed
262 vide these CTCF sites into three categories: intergenic sites remote from any coding element, upstrea
264 e an intronic SNP in FOXP1 at locus 3p13, an intergenic SNP at 3q28 near TP63, and an intergenic SNP
266 identified 35 SNPs in 12 wheat genes and one intergenic SNP in the Sbwm1 region that showed a signifi
269 e a potential mechanism for trait-associated intergenic SNPs that may contribute to phenotypic variat
271 that contained a transposon inserted in the intergenic space between sufC and sufD (sufD*), resultin
280 noncoding RNAs from the ribosomal DNA (rDNA) intergenic spacers, consistent with its previously repor
282 P2 and other latency-associated transcripts, intergenic splicing at the BZLF2 locus, and antisense tr
285 tion sequence and expression conservation of intergenic transcribed regions (ITRs) in four Poaceae sp
286 ammatory conditions via the production of an intergenic transcript linking neuronal and immune Fpr ge
287 s of genomes has raised the question whether intergenic transcription represents the activity of nove
289 nscripts and from DUX4-induced dsRNA-forming intergenic transcripts enriched for endogenous retroviru
291 ll genomic regions including exons, introns, intergenic, TTS (transcription termination sites) and pr
294 authors discovered 2 novel AF variants, the intergenic variant rs72700114, between the genes LINC011
295 ocus and upstream of EMSY; EMSY, LRRC32, and intergenic variants all appear to be within a single top
298 summary, we identified and characterized an intergenic VNTR polymorphism in S. pyogenes that affects
300 and silencing were used to identify a novel intergenic Y-linked lncRNA, named lnc-KDM5D-4, and inves