ライフサイエンスコーパス: interstrand

1 ive of different EBS1-(d)IBS1 geometries and interstrand affinities.

2 actin filaments through its effect on their interstrand and intrastrand contacts.

3 ssivity is mainly required for resistance to interstrand and intrastrand cross-linking agents, but no

4 A lesions, including nucleobase monoadducts, interstrand and intrastrand cross-links, and DNA-protein

5 Moreover, RTEL1 is involved in interstrand and intrastrand DNA cross-link repair indepe

6 ogical M(2+) concentrations strongly promote interstrand association.

7 ypsoralen, are used to covalently cross-link interstrand base pairs in DNA bonds that, in part, defin

8 ed DNA duplex forms a zipper via alternating interstrand base stacking, rather than melting as genera

9 , chemically stable, and photostable PAH LNA interstrand communication systems, including pyrene exci

10 uclease 1 (FAN1), a nuclease involved in DNA interstrand cross link repair.

11 MS and UV-sensitive protein81 in response to interstrand cross links and alkylated bases, whereas it

12 y integrity, recruiting FANCM to the site of interstrand cross links, preventing the cells from enter

13 MSH2 preferentially binds a cisplatin interstrand cross-link (ICL) DNA substrate containing a

14 Quantitative DNA interstrand cross-link (ICL) formation was observed with

15 Interstrand cross-link (ICL) hypersensitivity is a chara

16 The role of RAD51C in the FA pathway of DNA interstrand cross-link (ICL) repair and as a tumor suppr

17 Normal BRIP1 activity is required for DNA interstrand cross-link (ICL) repair and is thus central

18 Fanconi anemia (FA) pathway participates in interstrand cross-link (ICL) repair and the maintenance

19 rotein has nuclease activity and acts in DNA interstrand cross-link (ICL) repair within the Fanconi a

20 During eukaryotic DNA interstrand cross-link (ICL) repair, cross-links are res

21 of FA genes, which together constitute a DNA interstrand cross-link (ICL) repair, or the FA pathway.

22 is thought to involve FAN1's function in DNA interstrand cross-link (ICL) repair.

23 145), we investigated the role of WRN in the interstrand cross-link (ICL) response in cells derived f

24 evel of recruitment of FAN1 nuclease and DNA interstrand cross-link (ICL) unhooking.

25 strand cross-link or a cisplatin 5'-GC/5'-GC interstrand cross-link (ICL) were utilized in binding as

26 o generate a complex lesion consisting of an interstrand cross-link adjacent to a strand break.

27 he dynamics were suppressed by an engineered interstrand cross-link in the dsDNA that prevented unwin

28 t insights into the effects of an AP-derived interstrand cross-link on the efficiency and accuracy of

29 A-family polymerase with a putative role in interstrand cross-link repair and homologous recombinati

30 Here, we define a fundamental role for DNA interstrand cross-link repair in the germline.

31 s including the base excision repair and the interstrand cross-link repair pathways via its DNA glyco

32 on and its ability to promote error-free DNA interstrand cross-link repair, leading to increased erro

33 A new type of interstrand cross-link resulting from the reaction of a

34 asic (Ap) site in duplex DNA can generate an interstrand cross-link via reaction with a guanine resid

35 valently in the DNA minor groove, forming an interstrand cross-link.

36 r by a restriction nuclease or by a targeted interstrand cross-link.

37 intricate spatial arrangement and elaborate interstrand cross-linkages, they are difficult to prepar

38 Interstrand cross-linked (ICL) dG-MC-dG-DNA adducts can

39 sensitized rhabdomyosarcoma cells to the DNA interstrand cross-linker (ICL) melphalan.

40 ith this model, cells lacking RNF4 exhibited interstrand cross-linker hypersensitivity, and the gene

41 By assaying for sensitivity of cells to the interstrand cross-linker mitomycin C, we found that trea

42 bryo fibroblasts sensitizes cells to the DNA interstrand cross-linking (ICL) agent cisplatin.

43 cated in repairing DNA damage induced by DNA interstrand cross-linking (ICL) agents, topoisomerase I

44 in increased cellular sensitivity to the DNA interstrand cross-linking agent mitomycin C and the topo

45 instability observed after exposure to a DNA interstrand cross-linking agent.

46 rase REV1 are required for resistance to DNA interstrand cross-linking agents such as cisplatin.

47 pwise bisquinone methide formation increased interstrand cross-linking efficiency.

48 this is the first example of photoswitchable interstrand cross-linking formation induced by a modifie

49 isomerase poisons, DNA synthesis inhibitors, interstrand cross-linking inducers, and base-damaging ag

50 biocompatible strategy for photoinduced DNA interstrand cross-linking is presented.

51 tivity to DNA-damaging agents, in particular interstrand cross-linking-inducing agents.

52 ced formation of bisquinone methides for DNA interstrand cross-linking.

53 present in living cells and tissue, based on interstrand cross-linking.

54 necessary tools to achieve selective duplex interstrand cross-linking.

55 A particularly lethal lesion are interstrand cross-links (ICL), a property exploited by s

56 ycosylases capable of unhooking highly toxic interstrand cross-links (ICLs) and bulky minor groove ad

57 uclei where it is important in repair of DNA interstrand cross-links (ICLs) and chromosome stability.

58 accompanied by enhanced repair of cisplatin interstrand cross-links (ICLs) and ICL-induced DNA doubl

59 DNA interstrand cross-links (ICLs) are a form of DNA damage

60 DNA interstrand cross-links (ICLs) are cytotoxic products of

61 Interstrand cross-links (ICLs) are extremely toxic DNA l

62 Interstrand cross-links (ICLs) are highly cytotoxic DNA

63 Interstrand cross-links (ICLs) are highly toxic DNA lesi

64 DNA interstrand cross-links (ICLs) are highly toxic lesions

65 DNA interstrand cross-links (ICLs) are repaired in S phase b

66 Among these adducts, interstrand cross-links (ICLs) are the most toxic, as th

67 DNA interstrand cross-links (ICLs) are toxic DNA lesions who

68 om single-stranded DNA (ssDNA) and unhooking interstrand cross-links (ICLs) at fork structures.

69 DNA interstrand cross-links (ICLs) block replication fork pr

70 ice displayed marked hypersensitivity to DNA interstrand cross-links (ICLs) but not whole-body irradi

71 ve both been implicated in the repair of DNA interstrand cross-links (ICLs) by cellular studies, and

72 Interstrand cross-links (ICLs) covalently link complemen

73 Recent reports that BrdU yields DNA interstrand cross-links (ICLs) in non-base-paired region

74 MutSbeta heteroduplex, which interacts with interstrand cross-links (ICLs) induced by drugs such as

75 ation but are sensitive to agents that cause interstrand cross-links (ICLs) or replication stress.

76 ) pathway is essential for the repair of DNA interstrand cross-links (ICLs), and a germline defect in

77 R) repair of double-strand breaks (DSBs) and interstrand cross-links (ICLs), but its mechanism of act

78 play an important role in the repair of DNA interstrand cross-links (ICLs), but the precise mechanis

79 ion of Fancd2 is essential for repairing DNA interstrand cross-links (ICLs), but the underlying mecha

80 d primarily to their ability to generate DNA interstrand cross-links (ICLs), which effectively block

81 cterized by cellular hypersensitivity to DNA interstrand cross-links (ICLs).

82 nvolved in replication-coupled repair of DNA interstrand cross-links (ICLs).

83 f 15 FA genes responsible for processing DNA interstrand cross-links (ICLs).

84 zed to benzyl cations directly producing DNA interstrand cross-links (ICLs).

85 epair of DNA double-strand breaks (DSBs) and interstrand cross-links (ICLs).

86 drome caused by defects in the repair of DNA interstrand cross-links (ICLs).

87 roteins function cooperatively to repair DNA interstrand cross-links (ICLs).

88 m a specific type of DNA damage; namely, DNA interstrand cross-links (ICLs).

89 1 endonuclease is required for repair of DNA interstrand cross-links (ICLs).

90 sm of the stepwise formation of 5'-5' 1,4-GG interstrand cross-links (IXLs) by fully (15)N-labeled [{

91 th published work showing that KP1019 causes interstrand cross-links and bulky DNA adducts in mammali

92 ates with a decreased level of repair of DNA interstrand cross-links and chromosomal instability in F

93 was complete unhooking of cisplatin-induced interstrand cross-links and repair of IR-induced strand

94 or NLS mutations showed reduced unhooking of interstrand cross-links and repair of strand breaks.

95 s toward ROS was determined by measuring DNA interstrand cross-links and/or DNA alkylations.

96 DNA interstrand cross-links are an important family of DNA d

97 Interstrand cross-links are exceptionally bioactive DNA

98 Interstrand cross-links are produced upon irradiation of

99 cells appeared to depend almost entirely on interstrand cross-links at GpCpN motifs.

100 midine nucleotides, the aryl iodides produce interstrand cross-links in duplex regions of DNA when ex

101 inhibitor of DNA polymerase beta, and forms interstrand cross-links in free DNA.

102 Endogenous generation of interstrand cross-links in genomic DNA may contribute to

103 ctin, a small-molecule genotoxin that causes interstrand cross-links in host cell DNA.

104 We determined that MrfAB failed to unhook interstrand cross-links in vivo, suggesting that MrfAB a

105 Nucleotide excision repair (NER), interstrand cross-links repair (ICL/R), double-strand br

106 cient repair of DNA double strand breaks and interstrand cross-links requires the homologous recombin

107 ing because the highly deleterious nature of interstrand cross-links suggests that even small amounts

108 M), which is required for the repair of DNA interstrand cross-links to ensure replication progressio

109 halide nucleotide analogues that produce DNA interstrand cross-links under anaerobic conditions upon

110 Upon irradiation, these molecules yield DNA interstrand cross-links under anaerobic conditions.

111 Duplex DNA containing 4-6 forms interstrand cross-links upon gamma-radiolysis under anae

112 The phenyl seleneate yields interstrand cross-links when part of a duplex and is use

113 alkylation damage), mitomycin C (generating interstrand cross-links), or potassium bromate (generati

114 itive specifically to UV irradiation and DNA interstrand cross-links, similar to cells lacking ERCC1.

115 y is pivotal for the efficient repair of DNA interstrand cross-links.

116 pathway that is required for excision of DNA interstrand cross-links.

117 t with the opposing strand of DNA to produce interstrand cross-links.

118 cing and resistance to agents that cause DNA interstrand cross-links.

119 e sensitivity of Pso4-deficient cells to DNA interstrand cross-links.

120 replication-arresting DNA lesions including interstrand cross-links.

121 of replication-blocking lesions such as DNA interstrand cross-links.

122 are thought to function in the repair of DNA interstrand cross-links.

123 ) pathway is essential for the repair of DNA interstrand cross-links.

124 yclobutane pyrimidine dimers (CPDs), and DNA interstrand cross-links.

125 failure and a reduced ability to remove DNA interstrand cross-links.

126 and Rev1 are essential for the repair of DNA interstrand crosslink (ICL) damage.

127 HES1, to form complexes that participate in interstrand crosslink (ICL) DNA repair and MEC different

128 other key cellular processes, including DNA interstrand crosslink (ICL) repair and DNA double-strand

129 DNA interstrand crosslink (ICL) repair requires a complex ne

130 s roles in nucleotide excision repair (NER), interstrand crosslink (ICL) repair, homologous recombina

131 During replication-coupled DNA interstrand crosslink (ICL) repair, the XPF-ERCC1 endonu

132 s in any of at least 16 genes regulating DNA interstrand crosslink (ICL) repair.

133 ng (NHEJ), homologous recombination (HR) and interstrand crosslink (ICL) repair.

134 The FA proteins function primarily in DNA interstrand crosslink (ICL) repair.

135 ynthesis (TLS) past a nitrogen mustard-based interstrand crosslink (ICL) with an 8-atom linker betwee

136 gulated target acting as one defense against interstrand crosslink (ICL)-inducing agents.

137 es profound cellular hypersensitivity to DNA interstrand crosslink lesions in vivo, highlighting the

138 emonstrated that neither mismatch repair nor interstrand crosslink repair affects the production of t

139 ing replication and its participation in DNA interstrand crosslink repair and/or heteroduplex rejecti

140 CM participates in recombination-independent interstrand crosslink repair by facilitating recruitment

141 esults suggest that FAN1 has a minor role in interstrand crosslink repair compared with true FA genes

142 otifs, SLX4 SIMs are dispensable for its DNA interstrand crosslink repair functions.

143 roper RAD51 function is important during DNA interstrand crosslink repair outside of homologous recom

144 the deficiency in replication-dependent DNA interstrand crosslink repair pathway commonly referred t

145 ce that BRCA1 plays an important role in DNA interstrand crosslink repair that is distinct from its e

146 genetic complementation groups implicated in interstrand crosslink repair, FANCJ encodes a DNA helica

147 ty-DNA double-strand break (DSB) repair, DNA interstrand crosslink repair, repair of stalled replicat

148 monoubiquitinated FANCD2 and is required for interstrand crosslink repair, suggesting that mutation o

149 lication-dependent and transcription-coupled interstrand crosslink repair, while SNM1B/Apollo is requ

150 tion and Fanconi anemia complex-mediated DNA interstrand crosslink repair.

151 e marrow failure disorder with defective DNA interstrand crosslink repair.

152 nconi anemia (FA) pathway is responsible for interstrand crosslink repair.

153 of its E3 ubiquitin ligase activity and DNA interstrand crosslink repair.

154 ng error-prone replicative lesion bypass and interstrand crosslink repair.

155 e phosphodiester backbone that surrounds the interstrand crosslink, generating a double-strand-break

156 When two replisomes converge at an interstrand crosslink, TRAIP ubiquitylates the replicati

157 ified NEIL1 protein bound stably to psoralen interstrand crosslink-containing synthetic oligonucleoti

158 ovarian cancer often include the use of DNA interstrand crosslink-inducing agents (e.g., platinum dr

159 and Bloom's complexes at the site of the DNA interstrand crosslink.

160 he two known pathways of replication-coupled interstrand-crosslink repair.

161 conferred resistance to mitomycin C (MMC, an interstrand crosslinker) and camptothecin (CPT, a type 1

162 reakage when treated with mitomycin C, a DNA interstrand crosslinker.

163 characterized by cellular sensitivity to DNA interstrand crosslinkers.

164 (FA) patients are extremely sensitive to DNA interstrand crosslinking (ICL) agents, but the molecular

165 nts cause defective cellular response to DNA interstrand crosslinking agent and telomere maintenance,

166 n, knockdown of NONO sensitizes cells to the interstrand crosslinking agent, cisplatin, whereas knock

167 disorder characterized by sensitivity to DNA interstrand crosslinking agents.

168 acted doses of 14 alkylating and similar DNA interstrand crosslinking drugs from medical records.

169 UVA irradiation also induces DNA interstrand crosslinking of S(4)TdR-containing duplex ol

170 ous cancers sensitizes a cancer cell line to interstrand-crosslinking (ICL) agents.

171 nd FANCD2, is required for the repair of DNA interstrand crosslinks (ICL) and related lesions(1).

172 Although NEIL3 has been shown to unhook interstrand crosslinks (ICL) in Xenopus extracts, how NE

173 ssor BRCA1, is crucial for the repair of DNA interstrand crosslinks (ICL), a highly toxic lesion that

174 ) pathway is important for the repair of DNA interstrand crosslinks (ICL).

175 ential for the recognition and repair of DNA interstrand crosslinks (ICL).

176 ay plays a central role in the repair of DNA interstrand crosslinks (ICLs) and regulates cellular res

177 CA pathway is critical for the repair of DNA interstrand crosslinks (ICLs) and the maintenance of chr

178 Defects in the repair of DNA interstrand crosslinks (ICLs) are associated with the ge

179 DNA interstrand crosslinks (ICLs) are cytotoxic lesions that

180 DNA interstrand crosslinks (ICLs) are extremely cytotoxic le

181 DNA interstrand crosslinks (ICLs) are generated by endogenou

182 DNA interstrand crosslinks (ICLs) are highly toxic because t

183 Interstrand crosslinks (ICLs) are highly toxic DNA lesio

184 Interstrand crosslinks (ICLs) are toxic DNA lesions that

185 esolving double-strand DNA breaks (DSBs) and interstrand crosslinks (ICLs) by homologous recombinatio

186 ins thought to function in the repair of DNA interstrand crosslinks (ICLs) comprise what is known as

187 tively resolve Holliday junctions and repair interstrand crosslinks (ICLs) in mammalian cells.

188 Repair of interstrand crosslinks (ICLs) requires the coordinated a

189 not essential for cells to survive toxic DNA interstrand crosslinks (ICLs), although MMR proteins bin

190 otein network is necessary for repair of DNA interstrand crosslinks (ICLs), but its control mechanism

191 Several important anti-tumor agents form DNA interstrand crosslinks (ICLs), but their clinical effici

192 DNA-DNA crosslinks, especially interstrand crosslinks (ICLs), cause cytotoxicity via bl

193 DNA interstrand crosslinks (ICLs), highly toxic lesions that

194 le-deficient cells are hypersensitive to DNA interstrand crosslinks (ICLs), indicating that BRCA1 has

195 DNA interstrand crosslinks (ICLs), inhibit DNA metabolism by

196 r hypersensitivity to agents that induce DNA interstrand crosslinks (ICLs), such as mitomycin C (MMC)

197 agents used in cancer chemotherapy cause DNA interstrand crosslinks (ICLs), which covalently link bot

198 However, interstrand crosslinks (ICLs), which preclude DNA unwind

199 itin are required for localizing SLX4 to DNA interstrand crosslinks (ICLs), yet how SLX4 is targeted

200 c nuclease involved in the processing of DNA interstrand crosslinks (ICLs).

201 ndependent function during the repair of DNA interstrand crosslinks (ICLs).

202 rticipates in a pathway of resistance to DNA interstrand crosslinks (ICLs).

203 cterized by cellular hypersensitivity to DNA interstrand crosslinks (ICLs).

204 lites which promote DNA damage, specifically interstrand crosslinks (ICLs).

205 (DSBs), angelicin monoadducts and trioxsalen interstrand crosslinks (ICLs).

206 were exposed to chemicals that generate DNA interstrand crosslinks (repaired by FA proteins), but no

207 Here we generate acetaldehyde-induced DNA interstrand crosslinks and determine their repair mechan

208 and repair of DNA double-strand breaks, DNA interstrand crosslinks and DNA damage during DNA replica

209 erphase, TRAIP helps replisomes overcome DNA interstrand crosslinks and DNA-protein crosslinks, where

210 fective in promoting replication traverse of interstrand crosslinks and is also inefficient in promot

211 se results define the repair pathways of DNA interstrand crosslinks caused by an endogenous and alcoh

212 nalogous to the mechanism used to repair the interstrand crosslinks caused by the chemotherapeutic ag

213 Inappropriate repair of interstrand crosslinks causes genomic instability, leadi

214 DNA interstrand crosslinks covalently link the two strands o

215 NEIL1 recognizes specifically and distinctly interstrand crosslinks in DNA, and can obstruct the effi

216 cts, the collision of replication forks with interstrand crosslinks initiates two distinct repair pat

217 the cellular level, hypersensitivity to DNA interstrand crosslinks is the defining feature in Fancon

218 itutional genomic disorders, suggesting that interstrand crosslinks may play a pathogenic role in suc

219 to aid replication machines to traverse DNA interstrand crosslinks prior to post-replication repair.

220 Left unrepaired, DNA interstrand crosslinks represent impassable hurdles for

221 Repair of DNA interstrand crosslinks requires action of multiple DNA r

222 to oxidative DNA damage and psoralen-induced interstrand crosslinks was differentially affected by th

223 hor complex that recognizes damage caused by interstrand crosslinks, a multisubunit ubiquitin ligase

224 damage, including DNA double-strand breaks, interstrand crosslinks, and DNA gaps.

225 as well as trioxsalen (psoralen)-induced DNA interstrand crosslinks, but not to angelicin monoadducts

226 ke MUS81-EME1, is required for repair of DNA interstrand crosslinks, but this role appears to be inde

227 otoxic agents that generate alkylated bases, interstrand crosslinks, DNA-protein crosslinks, and doub

228 this groove for efficient digestion past DNA interstrand crosslinks, facilitating the key DNA repair

229 resolution of non-B DNA structures including interstrand crosslinks, G quadruplexes and DNA triplexes

230 alter the accumulation of NEIL1 at sites of interstrand crosslinks, suggesting distinct recognition

231 repair (BER) proteins in the response to DNA interstrand crosslinks, which block replication and tran

232 Their main role is in the repair of DNA interstrand crosslinks, which, by covalently binding the

233 ncreased activity of DNA2 and WRN at the DNA interstrand crosslinks.

234 core complex that mediates the repair of DNA interstrand crosslinks.

235 that senses and repairs damage caused by DNA interstrand crosslinks.

236 interfere with normal cellular processing of interstrand crosslinks.

237 A core complex to chromatin in repairing DNA interstrand crosslinks.

238 modification and repair of bulky adducts and interstrand crosslinks.

239 tion, an essential step in the repair of DNA interstrand crosslinks.

240 f damage, such as double-stranded breaks and interstrand crosslinks.

241 and facilitates replication traverse of DNA interstrand crosslinks.

242 ptures the interplay between intrastrand and interstrand decay channels.

243 the Xaa and Yaa positions, we conclude that interstrand dipole-dipole interactions are the primary d

244 In contrast, dsRNA is not able to reduce its interstrand distance and can only elongate by unwinding.

245 Interstrand distance is directly correlated with the sli

246 o the very different evolution of molecules' interstrand distance with the stretching force.

247 tal results that show, surprisingly, that an interstrand disulfide bond can stabilize parallel beta-s

248 beta-turns and twisted beta-hairpin without interstrand disulfide bonds.

249 p) to Cys-374 (C-terminal) but increases the interstrand disulfide cross-linking of Cys-265 (hydropho

250 s the antibiotic metronidazole (Mtz) into an interstrand DNA cross-linker.

251 Interstrand DNA cross-links (ICLs) are repaired by mecha

252 at interact with DNA forming intrastrand and interstrand DNA cross-links (ICLs).

253 cs, coordinate replication-coupled repair of interstrand DNA cross-links, and mitigate conflicts betw

254 ase complex, SLX4/MUS81/EME1, that processes interstrand DNA cross-links.

255 (FA) network is important for the repair of interstrand DNA cross-links.

256 recruitment of the Fanconi anemia complex to interstrand DNA crosslink sites and for interaction with

257 22 FANC genes (FANCA-W) involved in a common interstrand DNA crosslink-repair pathway.

258 Interstrand DNA crosslinks (ICLs) are a toxic form of DN

259 ucleases required for cellular processing of interstrand DNA crosslinks (ICLs).

260 ternative paired-end sequencing method using interstrand DNA photo cross-linking to covalently link t

261 A new type of interstrand DNA-DNA cross-link between abasic (Ap) sites

262 The resulting interstrand DNA-DNA cross-link occurs at 5'-ApT/5'-AA se

263 Interstrand DNA-DNA cross-links are highly toxic to cell

264 Interstrand DNA-DNA cross-links block replication and tr

265 mon type of endogenous DNA damage, can forge interstrand DNA-DNA cross-links via reaction with the ex

266 eotide repeat does not form stable intra- or interstranded DNA structures, being a DNA unwinding elem

267 pyrene excimer formation and pyrene-perylene interstrand Forster resonance energy transfer.

268 by applying it to probe the dynamic role of interstrand H-bond formation in the folding kinetics of

269 he folding rate, suggesting that most native interstrand H-bonds in beta-hairpins are formed only aft

270 rands 4 and 5 in the beta-barrel, which lack interstrand hydrogen bonding, and we speculate that it c

271 amides are outweighed by a network of strong interstrand hydrogen bonds.

272 ution to the lifetime changes comes from the interstrand hydrogen bonds.

273 itiated by hydrophobic collapse, followed by interstrand hydrogen-bond formation and turn formation.

274 and causing the formation of intrastrand and interstrand (ICL) crosslinks, but the precise downstream

275 uding analysis of functional consequences of interstrand interactions and mutations located at substa

276 But despite reasonably strong interstrand interactions, initial contacts frequently di

277 ead-to-tail fashion into linear strands with interstrand interactions.

278 function, as well as a model to account for interstrand loop entropy.

279 nd Tyr-338, are located on putatively mobile interstrand loops.

280 cy of photoreduction through intrastrand and interstrand pathways are observed.

281 A DNA interstrand photo-cross-linking reaction is possible via

282 Here, photoinduced interstrand proton transfer (PT) triggered by intrastran

283 n transfer induced by UV excitation triggers interstrand proton transfer in the alternating miniduple

284 al anions are present as tautomers formed by interstrand PT.

285 This suggests that perturbations of the interstrand region can destabilize spectrin tetramers an

286 alent head-to-head assays are located in the interstrand region.

287 nfinement entropy is already included in the interstrand repulsion free energy derived from osmotic s

288 in the CT theories this role is fulfilled by interstrand repulsion, and there is no explicit entropy

289 Here, we present an interstrand salt bridge between (4S)-aminoproline (Amp)

290 Overall, we propose interstrand separation and salt-bridge formation as key

291 resonance distance measurements capture the interstrand separation within monomer units during the t

292 opy reconstruction analysis to determine the interstrand spacing of double-stranded DNA encapsidated

293 lting replisome is liable to intrastrand and interstrand switches leading to replication errors.

294 2-thiothymine and 2,6-diaminopurine, and +1 interstrand zipper arrangements of intercalator-function

295 Probe duplexes with interstrand zippers comprising C and/or U monomers resul

296 -sequence dsDNA through modification with +1 interstrand zippers of intercalator-functionalized nucle

297 f double-stranded probes featuring different interstrand zippers of pyrene-functionalized monomers ba

298 obes are activated for DNA recognition by +1 interstrand zippers of pyrene-functionalized nucleotides

299 nts using Invader duplexes with different +1 interstrand zippers of the four canonical 2'-O-(pyren-1-

300 ition of dsDNA through modification with "+1 interstrand zippers" of 2'-N-(pyren-1-yl)methyl-2'-amino