ライフサイエンスコーパス: intestinal

1 Intestinal absorption of phosphate proceeds via an activ

2 a mechanism of impaired PLGA degradation and intestinal acidification confirming an important enteroh

3 resistance through lantibiotic expression or intestinal acidification, influence host mucosal immune

4 dge of the mechanisms underlying spontaneous intestinal adaptation, particularly in response to modif

5 strains demonstrated significantly enhanced intestinal adherence, biofilm formation, and pro-inflamm

6 thrombosis and intestinal infarction, total intestinal aganglionosis, and nonrecoverable congenital

7 Intestinal alkaline phosphatase (IAP) regulates bicarbon

8 ent resistance, peripheral blood samples and intestinal allograft biopsies from 51 ITx patients with

9 mia in rats plausibly due to the presence of intestinal alpha-glucosidase inhibitory and augmenting c

10 g the renin angiotensin system to regulating intestinal amino acid homeostasis and the gut microbiome

11 The human intestinal anaerobic commensal and opportunistic pathoge

12 ated by fewer than three barcoded viruses in intestinal and extraintestinal tissues.

13 nd activating distinct signaling pathways in intestinal and hepatic cells.

14 haSyn-induced behavioral deficits, including intestinal and motor impairments.

15 Outcome measures were: (i) Intestinal and renal histopathology; (ii) Renal function

16 ter mice, we identified discrete lineages of intestinal antigen-specific CD8(+) T cells, including a

17 ionate protect against hepatic IR injury and intestinal apoptosis/inflammation in intestinal TLR9 def

18 (n = 18), followed by ex vivo resection and intestinal autotransplantation (n = 12), ex vivo Whipple

19 ently, the O-protease OpeRATOR, derived from intestinal bacteria and expressed in Escherichia coli, h

20 Thus, symbiotic intestinal bacteria modulate antiviral immunity and leve

21 ck protein 60 and ameliorates the Lm-induced intestinal barrier dysfunction by blocking the nuclear f

22 sider, especially in HIV infection where gut-intestinal barrier dysfunction could facilitate T cell e

23 t bacterial overgrowth/dysbiosis and altered intestinal barrier function (gut-liver axis) and by epis

24 SCFAs maintained intestinal barrier function and reduced lipopolysacchari

25 Intestinal barrier function was assessed by analyzing im

26 ons between IECs and macrophages to maintain intestinal barrier function.

27 sential amino acid tryptophan, in regulating intestinal barrier function.

28 s, pathways of oxidative stress, and altered intestinal barrier function.

29 at positions the compromised blood-brain and intestinal barriers as important sources of microbial DN

30 commensal bacteria convert them into various intestinal BAs(2) that are important hormones that regul

31 Intestinal bile acids are known to modulate the germinat

32 ioides difficile Here we describe a role for intestinal bile acids in directly binding and neutralizi

33 Low numbers of L cells in intestinal biopsies and high serum levels of GLP-2 were

34 es, or CD8(+) T cells directly isolated from intestinal biopsies, with gammac cytokines in presence o

35 As well as risking injuries due to gastro-intestinal blockage, ingestion of foamed PS exposes anim

36 cue netrin-1, acts as a tumor suppressor in intestinal cancer and lung metastasis by triggering canc

37 LRP5/6-beta-catenin-IL-10 signaling axis in intestinal CD11c(+) APCs protects mice from CAC by regul

38 fy bacteria that are specifically present in intestinal CD14(+)CD11c(+) macrophages of Crohn's diseas

39 promoted gut microbiome shifts and enhanced intestinal CD8 T cell responses.

40 Trimethylamine and cadaverine inhibited intestinal cell growth.

41 nd that interactions between these cells and intestinal cell types were associated with resistance to

42 Adherence to host intestinal cells mediated by ETEC fimbriae is believed t

43 oma (DRA) protein, encoded by SLC26A3, a key intestinal chloride anion exchanger, has recently been i

44 echanisms include reduced bioavailability of intestinal cholesterol and alterations in endogenous cho

45 Intestinal colonization and within-household transmissio

46 duced by the host and microbiota to initiate intestinal colonization of avian and animal hosts for co

47 after FMT, 8 of 16 (50%) patients developed intestinal colonization with Blastocystis, with identica

48 Intestinal colonization with GBS induces an endogenous I

49 (T3SS1) in this pathogen leads to decreased intestinal colonization, which suggests that T3SS1 repre

50 proteolysis the most (f-ratio = 5.86), while intestinal conditions were the major determinants of lip

51 particles have been compared under simulated intestinal conditions.

52 Enteroendocrine cells (EECs) sense intestinal content and release hormones to regulate gast

53 ton pump inhibitors in simulated stomach and intestinal contents, as well as comparing name-brand and

54 RNA-Seq analysis of freshly isolated intestinal crypt cells showed that Bccip deletion caused

55 Both receptors are coexpressed in intestinal crypt stem cells, bind to R-spondins (RSPOs)

56 se the levels of nuclear beta-catenin in the intestinal crypt, augmenting CRC tumorigenesis in an ade

57 NRG1 deletion reduces proliferation in intestinal crypts and compromises regeneration capacity.

58 ein-coupled receptor 43-GLP-1 pathway in the intestinal crypts may be involved in the pathogenesis of

59 mbryonic kidney tips, as well as homeostatic intestinal crypts.

60 Lipopolysaccharide (LPS)-mediated intestinal damage, driven by STAT1-induced inflammation,

61 hytate ingestion promoted recovery following intestinal damage.

62 The major intestinal DC subsets (CD103(+)CD11b(-), CD103(-)CD11b(+

63 fish with disruption of ttc7a, which develop intestinal defects, and colonoids derived from biopsy sa

64 e of galactosyl-fructose linkages during its intestinal degradation.

65 r discuss how these properties contribute to intestinal development and the dynamics of injury-induce

66 High proportion of SCFAs remaining after the intestinal digestion (~65%) shows promise in the use of

67 d timepoints throughout in vitro gastric and intestinal digestion for differences in peptide profiles

68 Regardless of species, in vitro gastric and intestinal digestion released a higher concentration of

69 and 80:20) were subjected to in vitro gastro-intestinal digestion using a semi-dynamic gastric model,

70 ugh in vitro simulation of oral, gastric and intestinal digestions.

71 ol group comprised individuals without known intestinal disease who were referred for colorectal canc

72 ivity and they even precede the onset of the intestinal disease, while episcleritis are common define

73 al neurological, metabolic, psychiatric, and intestinal disorders, paving the way to develop drugs to

74 aining Paneth cell alertness to pathogens in intestinal disorders.

75 Whereas, for anti-osteoporotic products and intestinal dysbiosis treatment, bitter orange is more pr

76 al gastrointestinal disorder associated with intestinal dysbiosis.

77 anti-RFX6 autoantibodies and diarrheal-type intestinal dysfunction.

78 tro share the highest similarity with native intestinal ECs relative to kidney and lung.

79 t be induced by a combination of gastric and intestinal effectors and (ii) chlamydial colonization in

80 Human intestinal enteroids (HIEs) are primary epithelial cell

81 r conditions mimicking the adult human small intestinal environment.

82 ted with dysbiosis, resulting in compromised intestinal epithelial barrier and chronic mucosal inflam

83 unction in mice with a genetic impairment in intestinal epithelial barrier function, junctional adhes

84 Using mice with inducible intestinal epithelial cell (IEC)-specific deletion of Ph

85 fluid flow application initiates changes in intestinal epithelial cell characteristics relative to t

86 thylamine and tryptamine toxicity on a human intestinal epithelial cell line.

87 he licensing of cytotoxic T cells to mediate intestinal epithelial cell lysis.

88 used to compare the role of myeloid- versus intestinal epithelial cell-derived IL-33 during dextran

89 F and EC co-culture on patient-derived human intestinal epithelial cells (HIECs), and incorporate per

90 Here, we integrated intestinal epithelial cells (IEC) derived from human int

91 Intestinal epithelial cells (IEC) exclusively express th

92 Among barrier cells, intestinal epithelial cells (IECs) are particularly depe

93 Myeloid cells interact with intestinal epithelial cells (IECs) by producing various

94 ed C2BBe1 cells as a model, we observed that intestinal epithelial cells (IECs) were permissive to EV

95 tion, where it alters nutrient metabolism in intestinal epithelial cells and microbiome, leading to i

96 ulators of innate immune signaling, in HT-29 intestinal epithelial cells challenged with TNF-alpha or

97 Here, we show that intestinal epithelial cells expressing IRE1beta have an

98 Here, we elucidate a mechanism of action on intestinal epithelial cells for extracellular CDNs.

99 ole of the chromatin remodeling machinery in intestinal epithelial cells in the colitis response and

100 How intestinal epithelial cells interact with the microbiota

101 onstrate that constitutive AKT activation in intestinal epithelial cells markedly enhances tumor inva

102 that HDAC3 activity was sharply increased in intestinal epithelial cells of microbiota-replete mice c

103 the autophagy gene Atg7 specifically in all intestinal epithelial cells or in Lgr5(+)ISC, we show th

104 scripts in specific respiratory, corneal and intestinal epithelial cells, potentially explaining the

105 owever, as LT also promotes ETEC adhesion to intestinal epithelial cells, we postulated that increase

106 Thereafter, T. trichiura larvae moult within intestinal epithelial cells, with adult worms embedded i

107 viral replication, is found predominantly in intestinal epithelial cells, with chromogranin A-positiv

108 oliferation and epithelial restitution after intestinal epithelial injury.

109 morphogenic signaling gradients intrinsic to intestinal epithelial stem cells, Nikolaev et al.

110 showed it to efficiently cross healthy human intestinal epithelium (SMI-100) by a vesicular transcyto

111 can provide insights into the biology of the intestinal epithelium and innate immune responses.

112 ion between symbiotic microorganisms and the intestinal epithelium and the effective killing of penet

113 n, the loss of TMIGD1 significantly impaired intestinal epithelium brush border membrane, junctional

114 " and "reserve" stem cell populations in the intestinal epithelium has been debated since 1977.

115 The intestinal epithelium is a highly dynamic structure that

116 In the intestinal epithelium of Hnf4alphagamma(DKO) mice, expre

117 dysfunction, telomerase reactivation in the intestinal epithelium or pharmacological inhibition of A

118 higher affinity for bacteria than simulated intestinal epithelium, a valuable activity at therapeuti

119 eria or bacterial products through the small intestinal epithelium.

120 nal lumen and increased proliferation of the intestinal epithelium.

121 ation via interaction with circPABPN1 in the intestinal epithelium.

122 dstream infection experienced a prior marked intestinal expansion of pathogenic Candida species; this

123 The intestinal expansion of pathogenic Candida spp. was asso

124 Both intestinal exposure to InsP(3) and phytate ingestion pro

125 We identified hundreds of genes with intestinal expression undetected by previous approaches.

126 e results underline the suitability of these intestinal extracts under the studied conditions, as a r

127 an be life-saving for patients with advanced intestinal failure experiencing complications of parente

128 transplantation in the event of progressive intestinal failure-associated liver disease, progressive

129 Moreover, we show that intestinal flow and bacterial motility are potential tar

130 ntestine indicate important contributions to intestinal function and organismal wellbeing.

131 an expression profile consistent with normal intestinal function but also show distinct molecular sig

132 Striking similarities in host Fe status, intestinal functionality and gut microbiome were observe

133 ry content(1), regulating both physiological intestinal functions such as nutrient absorption and mot

134 c nervous system (ENS) coordinates essential intestinal functions through the concerted action of div

135 issue injury as observed in a mouse model of intestinal graft-versus-host disease (GVHD), providing a

136 orably alter the microbiome and improve host intestinal health in both pigs and humans exposed to Tri

137 MCL1, another member of the BCL2 family, in intestinal homeostasis in mice.

138 tal roles for Lats1/2 in adult, Wnt-mediated intestinal homeostasis through TEAD-dependent and -indep

139 nutrient absorption to pathogen sensing and intestinal homeostasis.

140 e axis in calibrating rapid 5-HT release for intestinal homeostasis.

141 viral protection but minimizes disruption of intestinal homeostasis.IMPORTANCE Enteric viral infectio

142 Taken together, we propose that individual intestinal IF polypeptides contribute in different ways

143 Mechanistically, butyrate induced small intestinal IL-10 expression and downregulated the claudi

144 Instead, a low percentage of intestinal ILC2s produced IL-10 at steady state.

145 l studies have shown that resetting the host intestinal immune responses by treatment with either a h

146 Lyz1-deficiency diminished intestinal immune responses to bacterial molecular patte

147 Many pathogens subvert intestinal immunity to persist within the gastrointestin

148 Additionally, the BLP increases intestinal immunomodulatory functions by recruiting FOXP

149 re, extensive mesenteric vein thrombosis and intestinal infarction, total intestinal aganglionosis, a

150 ed dramatic, female-specific exacerbation of intestinal inflammation accompanied by significant reduc

151 Moreover, we observed increased small intestinal inflammation and apoptosis after hepatic IR i

152 microflora is inextricably linked to chronic intestinal inflammation and colitis-associated colorecta

153 wild-type (WT) mice evidenced by more severe intestinal inflammation and impaired bacterial clearance

154 fate sodium-induced colitis due to prolonged intestinal inflammation and impaired tissue repair.

155 Resolution of intestinal inflammation and wound repair are active proc

156 with Cj-P1-DCA-Anaero showed attenuation of intestinal inflammation compared to Cj-P1.

157 -monocyte progenitors (GMP) during joint and intestinal inflammation in experimental spondyloarthriti

158 iRNA profiling and SCFA level in response to intestinal inflammation.

159 ed the severity of TcdA/B-induced damage and intestinal inflammation.

160 ic treatment, dramatically reduces IL-18 and intestinal inflammation.

161 have the potential to trigger or exacerbate intestinal inflammatory diseases.

162 We stimulated primary intestinal intraepithelial CD8(+) T-cell lines, or CD8(+

163 We show that intestinal IR induces rapid neutrophil mobilization alon

164 Sex differences in responses to intestinal ischemia-reperfusion (IR) have been recognize

165 -ILFs, respectively) as well as in GALT-free intestinal lamina propria (LP).

166 n be primed towards more colonic or proximal intestinal lineages in serum-free defined conditions.

167 Abdominal ultrasound confirmed an oedematous intestinal loop in a 70-mm-long hernial sac, with no cir

168 ce resulted in acute release of BAs into the intestinal lumen and increased proliferation of the inte

169 Solitary intestinal lymphoid tissues such as cryptopatches (CPs)

170 e show that a pathway mediating formation of intestinal lysosome-related organelles (LROs) is require

171 ck syndrome (IGS), which is characterized by intestinal malabsorption of vitamin B12 and in some case

172 Campylobacter jejuni monitors intestinal metabolites produced by the host and microbio

173 using DR CALUX(R) bioassay, before and after intestinal metabolization by Caco-2 cells.

174 Intestinal microbes and their metabolites affect the dev

175 e science have highlighted the importance of intestinal microbes in human physiology and disease path

176 itivity mediated by fermentation products of intestinal microbes in mice.

177 is our limited understanding of normal small intestinal microbial populations-progress in sampling te

178 covered associations between elements of the intestinal microbiome (including specific microbes, sign

179 The composition of the intestinal microbiome affects health from the prenatal p

180 We demonstrate that the intestinal microbiome contributes to cholestasis-mediate

181 Changes in the intestinal microbiome have been associated with obesity

182 The role of the intestinal microbiome in alcoholic hepatitis is not esta

183 Based on these data, features of the intestinal microbiome might be used for CRC screening an

184 FODMAP diet on persistent gut symptoms, the intestinal microbiome, and circulating markers of inflam

185 eport that trimethylamine N-oxide (TMAO), an intestinal microbiome-dependent metabolite, worsens graf

186 ecific differences in the composition of the intestinal microbiota and in susceptibility to metabolic

187 Features of the intestinal microbiota can affect development of the brai

188 The intestinal microbiota comprises diverse fungal and viral

189 Colon mucus segregates the intestinal microbiota from host tissues, but how it orga

190 Intestinal microbiota have been proposed to induce comme

191 Most studies focus on how intestinal microbiota influence cancer immunotherapy thr

192 ternal H. pylori status affects the maternal intestinal microbiota of both mother and newborn.

193 It is not clear whether alterations in the intestinal microbiota of children with celiac disease (C

194 , Arg1 was upregulated in an IL-4/IL-13- and intestinal microbiota-dependent manner.

195 eptibility, the immune system, and commensal intestinal microbiota.

196 ed in human bipolar disorder, and changes in intestinal microbiota.

197 nate immune response, are a key regulator of intestinal microenvironment homeostasis.

198 he gut to transduce sensory signals from the intestinal milieu to the brain through fast neurotransmi

199 using a semi-dynamic gastric model, a static intestinal model and an ex vivo absorption model (Ussing

200 goblet cells and a thick mucin barrier as an intestinal model to investigate Pic's roles during infec

201 treated with antibiotics partially restores intestinal motility.

202 eractions between vancomycin and gastric and intestinal mucins, resulting in very large aggregates an

203 from colonic ulcer biopsy revealed invasive intestinal mucormycosis.

204 he difficulty in directly sampling the small intestinal mucosa and microbial community (microbiota).

205 he gut microbiome communicates with both the intestinal mucosa and the systemic immune system, given

206 uridarum mouse infection model, we show that intestinal mucosa is infected via intranasal (i.n.) or p

207 The intestinal mucosa is lined by a single layer of epitheli

208 of B and T cells to the spleen, vaginal and intestinal mucosae, for example CCL25 enhanced splenic a

209 ubsets are abundantly present in genital and intestinal mucosal tissue and are among the first innate

210 This work validates the use of porcine small intestinal mucus collected from fully-grown pigs for stu

211 To create a model of the human intestinal mucus layer and gut microbiota, we used biore

212 athogenic C difficile and F nucleatum in the intestinal mucus layer.

213 y characteristics of human and porcine small intestinal mucus secretions to sub-micron sized particle

214 We studied the intestinal mycobiota in a cohort of patients with alcoho

215 environment with the physiological output of intestinal neural circuits to maintain gut homeostasis a

216 difficile; however, significant deficits in intestinal neutrophils and eosinophils were detected in

217 quently develops despite normal food intake, intestinal nutrient absorption and locomotor activity.

218 final diagnoses were malignancies 71 (36%), intestinal obstruction 11 (6%) and peptic ulcer disease

219 understanding of the role of this pathway in intestinal organogenesis, which is reviewed here.

220 of Blood, Matsuzawa-Ishimoto et al report an intestinal organoid-based platform that re-creates genet

221 Human pluripotent stem cell (hPSC)-derived intestinal organoids (HIOs) lack some cellular populatio

222 lumetric compression regulates the growth of intestinal organoids by modifying intracellular crowding

223 Of note, InsP(3) also induced growth of intestinal organoids derived from human tissue, stimulat

224 merase chain reaction and RNAscope) of small intestinal organoids incubated with the Notch inhibitor

225 n >1 million single cells derived from small intestinal organoids reveals cell-type- and cell-state-s

226 al epithelial cells (IEC) derived from human intestinal organoids with monocyte-derived macrophages,

227 In intestine tissues of mice and human intestinal organoids, MTG8 and MTG16 repress transcripti

228 platform could support long-term culture of intestinal organoids, potentially replacing the need for

229 ) reactions, to support routine passaging of intestinal organoids.

230 pha) is an antimicrobial peptide secreted by intestinal Paneth cells.

231 (HBV) infection, and 31.0% had at least one intestinal parasite.

232 ia, strongyloidiasis, schistosomiasis, other intestinal parasites, syphilis, gonorrhea, chlamydia, an

233 is proposed as a highly specific therapy for intestinal pathobiont elimination.

234 the morphological shape for C. jejuni as an intestinal pathogen.

235 diseases, both within the intestinal tract (intestinal pathogenic strains) and outside (extraintesti

236 Many intestinal pathogens, including Clostridioides difficile

237 th intravenous vancomycin chosen for its low intestinal penetrance (n = 12), and (3) caloric restrict

238 inhibitory circuits consisting of vasoactive intestinal peptide (VIP)-expressing and somatostatin (SO

239 vs submerged] and the presence of vasoactive intestinal peptide (VIP).

240 ectivity of pyramidal neurons and vasoactive intestinal peptide-expressing interneurons with long-ran

241 Case fatality rate from typhoid-associated intestinal perforation was substantial at 18% (2/11).

242 Utilizing a quantitative intestinal permeability assay, we performed an unbiased

243 Interleukin 1 beta (IL1B) increases intestinal permeability in mice.

244 ILC2s can enter the circulation after small intestinal perturbation by migratory helminths and move

245 Although most GCs are transient(3), those in intestinal Peyer's patches (PPs)-which depend on the gut

246 However, the small intestinal pGP3-deficient Chlamydia sp. failed to reach

247 These findings do not support the role of intestinal phosphate binders to reduce cardiovascular ri

248 neuronal signaling to coordinately modulate intestinal physiology and stress-responsive behavior, fu

249 nfirmed an indispensable role for vasoactive intestinal polypeptide-expressing SCN (SCN(VIP)) neurons

250 for augmenting the conventional detection of intestinal protozoa.

251 mmatory bowel disease, anorexia nervosa, and intestinal pseudo-obstruction.

252 m the development of therapies for enhancing intestinal repair after injury.

253 ting phenotype but also revealed a potential intestinal resistance to chlamydial spreading.

254 operties, reducing depressive-like behavior, intestinal SAA1 and SAA2 production, and hippocampal Th1

255 ymptoms and include central neuromodulators, intestinal secretagogues, drugs acting on opioid or 5-HT

256 that stably express gene modules across all intestinal segments, with graded, regional expression of

257 labeled endoscopic images collected from all intestinal segments.

258 reveal a mechanism regulating intestinal stem cell differentiation and epithelial repa

259 Its role in the regulation of intestinal stem cell function and differentiation, howev

260 ploiting Bellymount's capabilities, we track intestinal stem cell lineages and gut microbial coloniza

261 de-induced endothelial cell apoptosis boosts intestinal stem cell radiosensitivity.

262 These aging phenotypes are recapitulated in intestinal stem cell-specific Tsc1 knockout mice.

263 Proliferation of intestinal stem cells in MCL1-deficient mice required WN

264 gineered vessels (A-TEVs) comprised of small intestinal submucosa (SIS) immobilized with heparin and

265 Disrupting bacterial adherence to the intestinal surface could potentially target gastrointest

266 liver, kidney, lungs, immune system, gastro-intestinal system, skin as well as nervous system.

267 improved gut barrier integrity and increased intestinal T regulatory cells.

268 Ex-T(RM) cells, former intestinal T(RM) cells that rejoined the circulating poo

269 Hepatic TG production and intestinal TG absorption were unchanged in ppHF dams, bu

270 vides a rich foundation for developing novel intestinal therapeutics.

271 ctions between the gut and brain monitor the intestinal tissue and its microbial and dietary content(

272 human Duodenum Intestine-Chip that emulates intestinal tissue architecture and functions, that are r

273 elial mucus layer and reside deep within the intestinal tissue of animals.

274 ot possible because of the extremely fragile intestinal tissue perioperatively, and a conservative ap

275 was difference in specific taxa in fecal or intestinal tissue samples from patients with IBD vs cont

276 pon passive staining of mouse brain, lung or intestinal tissue surface with minute quantities of NanO

277 Intestinal tissues and derived enteroids from MYO5B(P663

278 Intestinal tissues from neonatal S100-knockout mice had

279 ibody enzyme-linked immunosorbent assay, and intestinal tissues were analyzed by histology.

280 Intestinal tissues were collected and analyzed by immuno

281 flammation and apoptosis after hepatic IR in intestinal TLR9 deficient mice.

282 onate protected against hepatic IR injury in intestinal TLR9 deficient mice.

283 ury and intestinal apoptosis/inflammation in intestinal TLR9 deficient mice.

284 using a variety of diseases, both within the intestinal tract (intestinal pathogenic strains) and out

285 The intestinal tract represents a portal of entry for many i

286 against invading bacterial pathogens in the intestinal tract, on the skin or on the vaginal mucosa.

287 elease of these therapeutic cells across the intestinal tract.

288 Intestinal transplantation (ITx) can be life-saving for

289 Temporary ileostomy during intestinal transplantation (ITx) is the standard techniq

290 ion and its associated side effects preclude intestinal transplantation if motivated only by an expec

291 ese teams, patients should be considered for intestinal transplantation in the event of progressive i

292 Compared with offering only intestinal transplantation, adding teduglutide cost ${\$

293 ot appear to confer survival advantage after intestinal transplantation.

294 risk factors for GVHD development following intestinal transplantation.

295 d, it is hoped, help revitalize the field of intestinal transplantation.

296 ion accompanied by significant reductions in intestinal Treg frequency and function.

297 e demonstrate that IEC-specific PHB1 combats intestinal tumorigenesis in the Apc(Min/+) mouse model b

298 ations that stabilize beta-catenin and cause intestinal tumors in mice and humans.

299 amine, the RIM and RIC interneurons, induced intestinal UPR(ER) activation and extended longevity, an

300 We identified the decreased intestinal VDR significantly correlated with reduction o

301 Infections with intestinal worms, such as Ascaris lumbricoides, affect h