ライフサイエンスコーパス: intestinal microbiota

1 (DAMP) signals derived from conditioning and intestinal microbiota.

2 from culturable bacteria) and ARDs from the intestinal microbiota.

3 n because of their inability to compete with intestinal microbiota.

4 s may play a role in sleep modulation by the intestinal microbiota.

5 logue of 3.9 million proteins from the human intestinal microbiota.

6 pplicability of new strategies targeting the intestinal microbiota.

7 ning and accompanying diversification of the intestinal microbiota.

8 te, reaches the colon to be fermented by the intestinal microbiota.

9 ve treatments that significantly disrupt the intestinal microbiota.

10 ated intestinal fibrosis without influencing intestinal microbiota.

11 tion of the diversity and composition of the intestinal microbiota.

12 ted responses of human CD4(+) T cells to the intestinal microbiota.

13 Here, we investigated the involvement of intestinal microbiota.

14 ave been shown to be vital components of the intestinal microbiota.

15 ted with host antigens, including autologous intestinal microbiota.

16 ed in human bipolar disorder, and changes in intestinal microbiota.

17 cooperative phenotypes within the mammalian intestinal microbiota.

18 ents in the establishment/maintenance of the intestinal microbiota.

19 tion of proteomics for functional studies of intestinal microbiota.

20 uman health benefits via their impact on the intestinal microbiota.

21 the gut, where their presence depends on the intestinal microbiota.

22 tibility to vancomycin-induced alteration of intestinal microbiota.

23 enefits of breastfeeding are conveyed by the intestinal microbiota.

24 and intestinal humoral responses and select intestinal microbiota.

25 this phenotype requires the presence of the intestinal microbiota.

26 cifically reduce the virome component of the intestinal microbiota.

27 n influencing the community structure of the intestinal microbiota.

28 mucosal surfaces and coats a fraction of the intestinal microbiota.

29 ic immune responses can be influenced by the intestinal microbiota.

30 g enterococci or between enterococci and the intestinal microbiota.

31 in has more impact than ciprofloxacin on the intestinal microbiota.

32 ids, the intestinal immune response, and the intestinal microbiota.

33 s to life in the cold are facilitated by the intestinal microbiota.

34 One possible modulator could be the intestinal microbiota.

35 acted from mouse fecal samples to assess the intestinal microbiota.

36 gnificantly affecting the structure of their intestinal microbiota.

37 s gnavus E1, a symbiont of the healthy human intestinal microbiota.

38 unopathological processes in response to the intestinal microbiota.

39 eptibility, the immune system, and commensal intestinal microbiota.

40 IBD and the potential to engineer patients' intestinal microbiota.

41 ported to be an important member of the host intestinal microbiota.

42 provides a method for precisely editing the intestinal microbiota.

43 ion by modulating the host's response to the intestinal microbiota.

44 nomic and functional characterization of the intestinal microbiota.

45 ied how exocrine pancreatic function affects intestinal microbiota.

46 AD patients have altered intestinal microbiota.

47 of a colon in continuity, and preserving the intestinal microbiota.

48 lcholine (PtC), or antigens expressed by the intestinal microbiota.

49 We showed considerable shifts within the intestinal microbiota 14-24 d postweaning in mice that w

50 the literature, particularly regarding small intestinal microbiota abundance and diversity, highlight

51 a2g1b by epithelial cells was dependent upon intestinal microbiota, adaptive immunity, and common-gam

52 he complex interactions between diet and the intestinal microbiota affect development of mucosal infl

53 recede arthritis, and that modulation of the intestinal microbiota after the onset of arthritis may o

54 NAFLD and the intestinal microbiota also differ between patients with

55 addition to pathogenic infections, commensal intestinal microbiota also has numerous significant immu

56 at additional environmental factors, such as intestinal microbiota alterations, are involved in its p

57 gs identify previously unknown links between intestinal microbiota alterations, circulating amino aci

58 al peptides, which leads to dysbiosis of the intestinal microbiota, alters the mucosal barrier, and p

59 fh cells demonstrated that they required the intestinal microbiota and a diverse repertoire of CD4(+)

60 (IBD) is characterized by alterations in the intestinal microbiota and altered immune responses to gu

61 determine the presence and levels of select intestinal microbiota and C. difficile toxin.

62 te that environmental factors, including the intestinal microbiota and changes in diet, can alter nor

63 e association between the composition of the intestinal microbiota and clinical features of irritable

64 e association between the composition of the intestinal microbiota and clinical features of irritable

65 pacts of metronidazole and vancomycin on the intestinal microbiota and colonization resistance are un

66 antibiotic administration, which changes the intestinal microbiota and compromises resistance to colo

67 significant and long-lasting effects on the intestinal microbiota and consequently reduce colonizati

68 Recent discoveries that linked intestinal microbiota and CVD have broadened our underst

69 growth stunting and components of the small intestinal microbiota and enteropathy and offer a ration

70 nces will allow clinicians to manipulate the intestinal microbiota and guide patient management in pa

71 Disruption of the intestinal microbiota and immune responses contribute to

72 100A8 and S100A9 regulate development of the intestinal microbiota and immune system in neonates.

73 erses the impact of Western diet (WD) on the intestinal microbiota and improves postoperative surviva

74 ecific differences in the composition of the intestinal microbiota and in susceptibility to metabolic

75 orbate 80 (P80) alter the composition of the intestinal microbiota and induce chronic low-grade infla

76 spect to the composition and function of the intestinal microbiota and intestinal integrity.

77 irectly via shifts in the composition of the intestinal microbiota and its products.

78 vailability of l-arginine as well as altered intestinal microbiota and metabolic products accounts fo

79 This Perspective discusses the role of intestinal microbiota and microbial metabolites in media

80 ncy, and their effects on development of the intestinal microbiota and mucosal immune system.

81 information on the functional activities of intestinal microbiota and on host-microbe interactions a

82 This effect was dependent on intestinal microbiota and production of acetate.

83 of orally infected mice that alters the host intestinal microbiota and promotes intestinal colonizati

84 , we discuss the novel and emerging field of intestinal microbiota and roles of gut permeability and

85 nd a prebiotic (OI) to selectively alter the intestinal microbiota and significantly reduce body weig

86 during early larval development requires the intestinal microbiota and that specific bacterial member

87 e association between the composition of the intestinal microbiota and the development of allergic di

88 eview summarizes the association between the intestinal microbiota and the development of allergic se

89 ew of the interactions occurring between the intestinal microbiota and the immune system, and we will

90 tion alters the composition of the bacterial intestinal microbiota and, conversely, that the presence

91 Antibiotic treatment can damage the intestinal microbiota and, paradoxically, increase susce

92 linkages between systemic/neuroinflammation, intestinal microbiota, and ammonia.

93 intestinal epithelial barrier function, the intestinal microbiota, and cytokine signaling in the pat

94 n humans, TMA is produced exclusively by the intestinal microbiota, and its metabolite, trimethylamin

95 bacter pylori, other members of the neonatal intestinal microbiota, and microbial peptides and metabo

96 ge, and the serum IgG response to a panel of intestinal microbiota antigens was assessed by using a n

97 lationship between the host and its resident intestinal microbiota, appropriate mucosal T cell respon

98 r, our results indicate that the majority of intestinal microbiota ARDs can be considered intrinsic t

99 Alterations in the intestinal microbiota are associated with atherosclerosi

100 hether bacterial and viral components of the intestinal microbiota are associated with this phenomeno

101 Intestinal microbiota are involved in the pathogenesis o

102 ested the hypothesis that alterations in the intestinal microbiota are linked with the progression of

103 ed on geographic and cultural differences in intestinal microbiota are necessary to define applicabil

104 responses directed against antigens from the intestinal microbiota are observed in certain diseases,

105 alterations to the structure and function of intestinal microbiota are sufficient to promote the meta

106 Results of this study implicate the intestinal microbiota as an important contributor to met

107 To determine features of the intestinal microbiota associated with health, however, w

108 summary a 3-day juice-based diet altered the intestinal microbiota associated with weight loss, incre

109 The composition of the intestinal microbiota became more similar across astrona

110 Depletion of intestinal microbiota by administration of broad-spectru

111 data also demonstrate that disruption of the intestinal microbiota by antibiotic treatment prevents p

112 flore), in 20 of the 64 NICUs, analyzed the intestinal microbiota by culture and 16S ribosomal RNA g

113 Modulation of intestinal microbiota by oral antibiotics or germ-free c

114 pAOS modified the intestinal microbiota by stimulating the growth of speci

115 Features of the intestinal microbiota can affect development of the brai

116 The intestinal microbiota can both positively and negatively

117 est whether the perioperative composition of intestinal microbiota can contribute to variable outcome

118 y have confirmed that the composition of the intestinal microbiota can imprint susceptibility or resi

119 For instance, the intestinal microbiota can prevent invading microbes from

120 Experimental evidence indicates that intestinal microbiota can transfer an obese phenotype fr

121 bjects with moderate genetic susceptibility, intestinal microbiota changes may be a factor that incre

122 wth failure have disrupted maturation of the intestinal microbiota, characterized by persistently low

123 olatile organic compounds (VOCs), reflecting intestinal microbiota composition and function, allow fo

124 ptibilities, and the potential of modulating intestinal microbiota composition and metabolism as a no

125 ve contributions of each of these factors on intestinal microbiota composition following VSG prior to

126 Further, the changes in intestinal microbiota composition related to the improve

127 SG resulted in weight loss and shifts in the intestinal microbiota composition relative to sham-opera

128 sed the relation between feeding strategies, intestinal microbiota composition, and the development o

129 Host immunity shapes intestinal microbiota composition, influencing health an

130 e gastrointestinal tract is regulated by the intestinal microbiota composition, particularly the pres

131 d intestinal permeability and changes in the intestinal microbiota composition, which contribute to t

132 on was associated with significantly altered intestinal microbiota composition, which was linked to a

133 sociated hepcidin induction is influenced by intestinal microbiota composition.

134 host factor to be associated with changes in intestinal microbiota composition.

135 The intestinal microbiota comprises diverse fungal and viral

136 fied the Bacteroides2 (Bact2) enterotype, an intestinal microbiota configuration that is associated w

137 Intestinal microbiotas contain beneficial microorganisms

138 ctions between the mucosal immune system and intestinal microbiota contribute to pathogenesis of infl

139 Here, we show that altered intestinal microbiota contributes to anti-tumor immunity

140 ize that generation of this biopterin by the intestinal microbiota contributes to its tissue increase

141 Antibiotic treatment altered intestinal microbiota, decreased tissue inflammation, im

142 , Arg1 was upregulated in an IL-4/IL-13- and intestinal microbiota-dependent manner.

143 Our evolving understanding of intestinal microbiota-derived physiological modulators (

144 nt metronidazole, are associated with marked intestinal microbiota destruction and greater risk of co

145 Anomalous intestinal microbiota development is supposedly associat

146 pectrum antibiotic treatment (to deplete the intestinal microbiota) did not alter the responses in Nr

147 sed vessel density, compositional changes in intestinal microbiota, diminished infiltration by myeloi

148 biotransformation of host metabolites by the intestinal microbiota directly and regionally impacts in

149 yte/T-cell activation, mucosal integrity, or intestinal microbiota diversity.

150 The intestinal microbiota drives host immune homeostasis by

151 Elimination of the intestinal microbiota during established arthritis speci

152 host mild but significant differences in the intestinal microbiotas during a critical early window of

153 Multiple factors help shape the infant intestinal microbiota early in life.

154 at these conditions, including modifying the intestinal microbiota early in life.

155 l cancer cell colonization or proliferation, intestinal microbiota effects, or tumoricidal activity b

156 aiotaomicron, a dominant member of the human intestinal microbiota, encodes polysaccharide utilizatio

157 ence has accumulated to demonstrate that the intestinal microbiota enhances mammalian enteric virus i

158 gA(-/-) and wild-type mice disappeared after intestinal microbiota equalization.

159 The recognition that intestinal microbiota exert profound effects on human he

160 ronment, which suggests major changes in the intestinal microbiota following movement to saltwater.

161 ouse mammary tumor virus (MMTV) requires the intestinal microbiota for persistence.

162 Our approach unlocks the human intestinal microbiota for phenotypic analysis and reveal

163 in normal diet-fed mice that received small intestinal microbiota from HFD-fed mice.

164 Colon mucus segregates the intestinal microbiota from host tissues, but how it orga

165 We colonized germ-free mice with intestinal microbiotas from 30 healthy and IBD donors an

166 ough April 2, 2018 for studies that compared intestinal microbiota (from fecal or colonic or ileal ti

167 standing how the mammalian immune system and intestinal microbiota functionally interact have yielded

168 Here we compared the intestinal microbiota harboured in the distal digesta of

169 Our intestinal microbiota harbours a diverse bacterial commu

170 experimental evidence demonstrates that the intestinal microbiota has an important impact on pancrea

171 As such, the intestinal microbiota has been advanced as an important

172 BACKGROUND & AIMS: Dysbiosis of the intestinal microbiota has been associated with developme

173 Dysbiosis of the intestinal microbiota has been associated with nonalcoho

174 The intestinal microbiota has been identified as an environm

175 Altering the intestinal microbiota has been proposed as a treatment f

176 The study of the intestinal microbiota has begun to shift from cataloging

177 The intestinal microbiota has increasingly been considered t

178 Hydrogen sulfide (H(2)S) production in the intestinal microbiota has many contributions to human he

179 s is well studied, its impact on shaping the intestinal microbiota has not been addressed in depth.

180 Various species of the intestinal microbiota have been associated with the deve

181 mmune response, intestinal inflammation, and intestinal microbiota have been established, many gaps i

182 ions in the composition and functions of the intestinal microbiota have been implicated in multiple d

183 Intestinal microbiota have been proposed to induce comme

184 The intestinal microbiota have been shown to affect precirrh

185 The impact of each of these factors on the intestinal microbiota have not been evaluated.

186 urinary 3-indoxyl sulfate is a biomarker of intestinal microbiota health and predicts reduced intest

187 to lead to durable alterations to the murine intestinal microbiota, ileal gene expression, specific i

188 h host and environmental antigens, including intestinal microbiota (IM).

189 cular, experimental manipulations that alter intestinal microbiota impact exploratory and communicati

190 We characterised the intestinal microbiota in 6-11 month-old infants in India

191 jective was to identify early differences in intestinal microbiota in a cohort of breastfeeding infan

192 Accordingly, depleting intestinal microbiota in AD animal models reduces amyloi

193 ted with alterations in the structure of the intestinal microbiota in both dosing models.

194 ids in fecal samples, and composition of the intestinal microbiota in children with overweight or obe

195 licated in changes in the composition of the intestinal microbiota in Crohn's disease, but its role o

196 Despite the well-appreciated roles of intestinal microbiota in driving inflammation in IBD, th

197 tive cancer, supporting a potential role for intestinal microbiota in mediating the association betwe

198 ions of fenugreek remain unknown, a role for intestinal microbiota in metabolic homeostasis is likely

199 This review discusses the roles of human intestinal microbiota in normal physiology, their associ

200 amentous bacteria (sfb), but the role of the intestinal microbiota in pulmonary host defense is not w

201 supporting the important role for early-life intestinal microbiota in the development of childhood as

202 have produced evidence for a causal role of intestinal microbiota in the etiology of obesity and ins

203 The potential role of intestinal microbiota in the etiology of various human d

204 cent studies uncovered significant roles for intestinal microbiota in this process, but underlying me

205 Jucara pulp can modulate the intestinal microbiota in vitro, promoting changes in the

206 tients without a C-seal can be linked to the intestinal microbiota, in particular with a low microbia

207 Transfer of intestinal microbiota, including members of the Clostrid

208 It was our hypothesis that changes in the intestinal microbiota induced by a juice-based diet play

209 Most studies focus on how intestinal microbiota influence cancer immunotherapy thr

210 The intestinal microbiota influence neurodevelopment, modula

211 The composition of the intestinal microbiota influences the development of infl

212 es in the diet can affect the interaction of intestinal microbiota influencing the immune system, whi

213 hogens and changes in the composition of the intestinal microbiota initiate this process, which leads

214 The intestinal microbiota is a complex community of bacteria

215 The intestinal microbiota is a dynamic community of bacteria

216 Emerging evidence suggests that the intestinal microbiota is a source of sleep-promoting sig

217 The intestinal microbiota is believed to be involved in the

218 The intestinal microbiota is composed by 500-1000 distinct s

219 better understand how the composition of the intestinal microbiota is connected to risk of gram-negat

220 The intestinal microbiota is considered to be a major reserv

221 The intestinal microbiota is considered to play an important

222 The intestinal microbiota is critical for maintaining homeos

223 tiple antibiotics, tend to colonize when the intestinal microbiota is dysbiotic, and elicit a severe

224 Intestinal microbiota is emerging as one of the key envi

225 The indigenous intestinal microbiota is frequently considered an additi

226 Moreover, it is now well admitted that the intestinal microbiota is involved in shaping and maturat

227 The infant intestinal microbiota is often colonized by two subspeci

228 the normal human adaptive immune response to intestinal microbiota is poorly defined.

229 ed to bacteria, the role of fungi within the intestinal microbiota is poorly understood.

230 s aureus and Staphylococcus epidermidis) and intestinal microbiota (Lactobacillus reuteri, Enterococc

231 odulatory activity or through effects on the intestinal microbiota leading to reduced microbial trans

232 we present a pipeline for the assessment of intestinal microbiota localization within immunofluoresc

233 , chronic infections and disturbances in the intestinal microbiota; low-grade mucosal inflammation, i

234 These observations suggest that altered intestinal microbiota may be associated with disease sus

235 An emerging body of work suggests that the intestinal microbiota may help to explain some of these

236 Alterations in the intestinal microbiota may play a role in microbial trans

237 A recent study suggested that early-life intestinal microbiota may play an important role in the

238 The intestinal microbiota might contribute to enteropathy as

239 Here, we have shown that the intestinal microbiota modulates inflammatory responses c

240 sulitis, an effect that was dependent on the intestinal microbiota; moreover, they developed autoimmu

241 hough both Toll and IMD effectors controlled intestinal microbiota, neither affected Trypanosoma cruz

242 Methods The intestinal microbiota of 541 patients admitted for allo-

243 east 50-60% of the bacterial genera from the intestinal microbiota of a healthy individual produce re

244 ternal H. pylori status affects the maternal intestinal microbiota of both mother and newborn.

245 It is not clear whether alterations in the intestinal microbiota of children with celiac disease (C

246 Although several alterations in the intestinal microbiota of children with established CD ap

247 The intestinal microbiota of finishing pigs, fed with 16%, 1

248 ibosomal RNA gene sequencing to characterize intestinal microbiota of free-ranging sympatric chimpanz

249 Experiments in which we manipulated the intestinal microbiota of mice revealed the existence of

250 Our aim in this study was to identify the intestinal microbiota of patients at risk for NEC.

251 The intestinal microbiota of patients with constipated-predo

252 Firmicutes are reduced in the intestinal microbiota of patients with ulcerative coliti

253 Conclusion: The altered intestinal microbiota of pregnancy enhance bile acid dec

254 The effect of alterations in intestinal microbiota on microbial metabolites and on di

255 The intestinal microbiota performs essential functions for h

256 Our observations suggest that intestinal microbiota perturbations precede arthritis, a

257 ause accumulating evidence has revealed that intestinal microbiota play an important role in human he

258 The intestinal microbiota plays a critical role in the devel

259 The intestinal microbiota plays a crucial role in influencin

260 The intestinal microbiota plays an important role in develop

261 The intestinal microbiota plays an important role in modulat

262 The human intestinal microbiota plays vital functions in nutrient

263 s have described how helminths may alter the intestinal microbiota, potentially representing a mechan

264 o assess the adaptive immune response to the intestinal microbiota present in 143 healthy adults and

265 Mice colonized with intestinal microbiota presented significantly higher PP

266 The intestinal microbiota produces tens of thousands of meta

267 BS and healthy individuals, we identified an intestinal microbiota profile that is associated with th

268 IELs, gene expression, gut permeability and intestinal microbiota profiles were measured.

269 Here, we show that the intestinal microbiota programs diurnal metabolic rhythms

270 The intestinal microbiota promote myriad functions that affe

271 The intestinal microbiota provides colonization resistance a

272 odeficient or chemotherapy-treated mice, the intestinal microbiota provides nonredundant defense agai

273 ngs provide mechanistic insight into how the intestinal microbiota regulates body composition and est

274 next-generation probiotics derived from the intestinal microbiota represents an alternative approach

275 ommunity of commensal microbes, known as the intestinal microbiota, resides within the gastrointestin

276 Further, 16S rRNA sequence analysis of the intestinal microbiota revealed marked changes in the com

277 Inhibition of FPRL1, but not suppression of intestinal microbiota, reversed these protective effects

278 By using this intestinal microbiota signature, we found IBS symptom se

279 In this study, the intestinal microbiota signatures associated with the sev

280 ation of copper in the GI tract of mice with intestinal microbiota significantly depleted by antibiot

281 Microbial cell components from the intestinal microbiota spread systemically in a healthy h

282 Intestinal microbiota, systemic and neuroinflammation (i

283 esting a stronger resilience capacity of the intestinal microbiota than cutaneous microbiota.

284 which lack all NKT cells, harbor an altered intestinal microbiota that is associated with exacerbate

285 icobacter hepaticus is a member of the mouse intestinal microbiota that is tolerated by the host.

286 The equilibrium linking the intestinal microbiota, the intestinal epithelium, and th

287 deplete commensal bacterial strains from the intestinal microbiota, thereby reducing colonization res

288 guts, SCFAs are mostly produced by anaerobic intestinal microbiota through the fermentation of dietar

289 potential therapeutic power of manipulating intestinal microbiota to ensure host metabolic health an

290 in vitro studies of the contribution of the intestinal microbiota to infectious disease are discusse

291 in ECs senses single-strand RNA (ssRNA) from intestinal microbiota to promote serotonin production.

292 Since mothers transmit intestinal microbiota to their offspring during labor, w

293 Intestinal microbiota undergo significant changes in col

294 The butyrate-producing capacity of the intestinal microbiota was also quantified.

295 Furthermore, proliferation rates and intestinal microbiota were analyzed in the mucosal speci

296 The intestinal microbiota, which is composed of bacteria, vi

297 The intestinal microbiota, which is composed of diverse popu

298 (reg) cells led to profound dysbiosis of the intestinal microbiota, which when transferred to germ-fr

299 The interplay of the intestinal microbiota with host metabolism has been show

300 AIMS: It might be possible to manipulate the intestinal microbiota with prebiotics or other agents to