ライフサイエンスコーパス: intracellular organelle

1 nsport compounds from the lumen of an acidic intracellular organelle.

2 redirecting transport vesicles and hijacking intracellular organelles.

3 e labeling of either neuronal cell bodies or intracellular organelles.

4 either by drug efflux or sequestration into intracellular organelles.

5 -R (R1 and R2) in HEK-293 cell membranes and intracellular organelles.

6 reen fluorescent protein remained trapped in intracellular organelles.

7 o maintain and adapt spatial organization of intracellular organelles.

8 ntial for regulating vesicular traffic among intracellular organelles.

9 operated channel activity and Ca2+ uptake by intracellular organelles.

10 vated at the expense of bulk Rap1 located on intracellular organelles.

11 fields to achieve selective manipulations of intracellular organelles.

12 and plasticity, and signaling pathways from intracellular organelles.

13 ated pit formation at the cell surface or on intracellular organelles.

14 of membrane proteins present on a variety of intracellular organelles.

15 oting functional crosstalk between different intracellular organelles.

16 association with cell membrane and possibly intracellular organelles.

17 low-pH-dependent fusion triggering in acidic intracellular organelles.

18 on of MG29 from the plasma membrane into the intracellular organelles.

19 both mZip1 and mZip3 were largely present in intracellular organelles.

20 ement across epithelia, and acidification of intracellular organelles.

21 segregation of membrane proteins to distinct intracellular organelles.

22 TPases) mediate the acidification of various intracellular organelles.

23 g that the remaining calcium originated from intracellular organelles.

24 metabolite flux across membranes of cells or intracellular organelles.

25 ingle-celled bacterium that presumably lacks intracellular organelles.

26 cell volume regulation and acidification of intracellular organelles.

27 f signaling proteins to send messages to the intracellular organelles.

28 angers were associated with the membranes of intracellular organelles.

29 microdomains on both the plasma membrane and intracellular organelles.

30 erentiated, nonendocytic cells that lack all intracellular organelles.

31 and the spatial distribution of Ca2+ within intracellular organelles.

32 effects on membrane permeability of multiple intracellular organelles.

33 h cell types, virions localized to acidified intracellular organelles.

34 ch probably consists mainly of iron bound to intracellular organelles.

35 s fuse with the plasma membrane but not with intracellular organelles.

36 d the coincident accumulation of cadherin in intracellular organelles.

37 function in vesicle formation from distinct intracellular organelles.

38 esting that betaIII spectrin associates with intracellular organelles.

39 he regulation of vesicle trafficking between intracellular organelles.

40 this protein in the membranes of specialized intracellular organelles.

41 ransmembrane proteins, and proteins found in intracellular organelles.

42 ract with the eukaryotic plasma membrane and intracellular organelles.

43 losure of macropinosomes and phagosomes into intracellular organelles.

44 tuate pattern suggestive of association with intracellular organelles.

45 nd function of integral membrane proteins of intracellular organelles.

46 nsistent with the reported effects of BFA on intracellular organelles.

47 rated channels, and it is not sequestered by intracellular organelles.

48 eract with the eukaryotic plasma membrane or intracellular organelles.

49 ne proteins, and CLICs, which are located on intracellular organelles.

50 amp technique, are not readily applicable to intracellular organelles.

51 ecurrence and metastasis by interacting with intracellular organelles.

52 r maintaining the integrity and functions of intracellular organelles.

53 s by manipulating the physical properties of intracellular organelles.

54 lasmic reticulum (ER), one of the most vital intracellular organelles.

55 ither the plasma membrane or the membrane of intracellular organelles.

56 les, and changes in receptor assembly within intracellular organelles.

57 uding the plasma membrane, cytoskeleton, and intracellular organelles.

58 ER, which contacts and modulates most other intracellular organelles.

59 l, co-factor-dependent recruitment of VCP to intracellular organelles.

60 lial cells; and an increase in the volume of intracellular organelles.

61 e and coordination of diurnal rhythmicity in intracellular organelles.

62 ration to driving cytokinesis to positioning intracellular organelles.

63 uired for endolysosomal membrane fusion with intracellular organelles.

64 iber cells contain the typical complement of intracellular organelles.

65 ases recruit peripheral membrane proteins to intracellular organelles.

66 nd fusion determine size and copy numbers of intracellular organelles.

67 ly used to monitor Zn(2+) in the cytosol and intracellular organelles.

68 cture and function of mitochondria and other intracellular organelles.

69 (2) in regulating the fusogenic potential of intracellular organelles.

70 that exist in most eukaryotic cells, such as intracellular organelles.

71 termittently shown the presence of BK(Ca) in intracellular organelles.

72 egulate pH by pumping cytosolic protons into intracellular organelles.

73 s sensitivity is a changing viscosity of the intracellular organelles.

74 only across the cell membrane but also into intracellular organelles.

75 tem to rapidly target proteins to individual intracellular organelles.

76 ontrol the pH and electrolyte composition of intracellular organelles.

77 TPase proton pump responsible for acidifying intracellular organelles.

78 oplasmic reticulum (ER) is a multifunctional intracellular organelle, a component of the cellular ret

79 asma membrane and the membranes of nanoscale intracellular organelles, a result we found to be due to

80 ks a fresh field of nanorobot operation with intracellular organelle access, thereby introducing the

81 ton pump inhibitors which increase the pH of intracellular organelles, after which TYR is transported

82 he calcium-induced calcium release from this intracellular organelle allowed for finely tuned "all-or

83 le the multiple glycan species released from intracellular organelle and cell surface glycoproteins,

84 recordings from subcellular compartments and intracellular organelles and allow precise manipulations

85 aggregates are not associated with any known intracellular organelles and are reversible by incubatin

86 t both receptors were profoundly retained in intracellular organelles and co-localized with the endop

87 tor 1, a negative effect on the structure of intracellular organelles and defective autophagy.

88 domain of Bcl-B impairs its association with intracellular organelles and diminishes its anti-apoptot

89 Vacuolar H(+)-ATPases (V-ATPases) acidify intracellular organelles and help to regulate overall ce

90 H(+)ATPases mediate acidification of various intracellular organelles and in some tissues mediate H(+

91 en implicated in maturational degradation of intracellular organelles and in the biosynthesis of anti

92 tisubunit complex responsible for acidifying intracellular organelles and is highly regulated.

93 ducing this dramatic morphological change in intracellular organelles and its relation to the functio

94 Autophagy is a process for turnover of intracellular organelles and macromolecules that protect

95 Autophagy is a process for turnover of intracellular organelles and molecules that protects cel

96 lysosomal pathway that degrades and recycles intracellular organelles and proteins to maintain energy

97 of intestinal SR-B1 from apical membranes to intracellular organelles and reduced chylomicron secreti

98 nd physiological stimuli alter the pH within intracellular organelles and suggest that NAADP signals

99 ase) is a rotary motor enzyme that acidifies intracellular organelles and the extracellular milieu in

100 ession of SARS-CoV-2 envelope (E) protein in intracellular organelles and the plasma membrane of mamm

101 microscopy to generate 3D reconstructions of intracellular organelles and their membrane appositions

102 t is well established that CFTR localizes to intracellular organelles and to apical membranes.

103 mechanisms rely on their ability to mobilize intracellular organelles and to deliver granular cargoes

104 n and myosin have been proposed to transport intracellular organelles and vesicles to the cell periph

105 rvatures and complex shapes required to form intracellular organelles and vesicular structures involv

106 tion from within eosinophil granules both as intracellular organelles and, as novelly demonstrated, a

107 o play an important role in the clearance of intracellular organelles, and autophagy-deficient mature

108 a(2+) regulation involves sequestration into intracellular organelles, and expeditious Ca(2+) release

109 ar vesicles that degrade protein aggregates, intracellular organelles, and other cellular components.

110 Curved membranes are key features of intracellular organelles, and their generation involves

111 Therefore, the cross-fusion of intracellular organelles appears to be a new mechanism t

112 ttering structures from the visual axis, all intracellular organelles are eliminated from cells in th

113 is a homeostatic process whereby cytosol or intracellular organelles are sequestered by a double mem

114 Eosinophil granules, in addition to being intracellular organelles, are found as intact membrane-b

115 Fatp4 mutants, and FATP1 sorted to the same intracellular organelles as endogenous FATP4.

116 principles that govern the size of cells and intracellular organelles as well as associated biologica

117 ron microscopy revealed the disappearance of intracellular organelles, as well as the disappearance o

118 with additional participation of the NCX and intracellular organelles at high [Ca(2+)]i.

119 with additional participation of the NCX and intracellular organelles at high [Ca2+]i.

120 atients demonstrates impaired trafficking of intracellular organelles because of obstruction by vacuo

121 ion events that occur during endocytosis and intracellular organelle biogenesis through the combined

122 Cells tightly regulate trafficking of intracellular organelles, but a deeper understanding of

123 ication is required for the function of many intracellular organelles, but methods to acutely manipul

124 protein vti1a is proposed to drive fusion of intracellular organelles, but recent data also implicate

125 e of assembly of SIV is not redirected to an intracellular organelle by the retrieval of the Env prot

126 of zinc influx, efflux, and distribution to intracellular organelles by zinc transporters.

127 therapy-induced apoptosis through disrupting intracellular organelle calcium ion (Ca(2+)) release in

128 mary melanocytes from which they arise, have intracellular organelles, called melanosomes, wherein th

129 re human erythrocytes, known to be devoid of intracellular organelles, can sequester ATP, but they ma

130 n shares extensive homology with a family of intracellular organelle chloride channels but is the fir

131 the plasma membrane to endosomes to form an intracellular organelle Cl channel had a low pH of appro

132 The apicoplast (an intracellular organelle) contains an approximately 35-kb

133 er switch for cell growth and trafficking of intracellular organelles, controls the acidification of

134 action of PHMB with membranes suggests other intracellular organelles could be potential targets of i

135 Distinct lipid compositions of intracellular organelles could provide a physical basis

136 Lipid droplets (LDs) are intracellular organelles critical for energy storage and

137 To explore how intracellular organelle distributions affect cellular fu

138 Intracellular organelles do not, as thought for a long t

139 applications, including the visualization of intracellular organelles, drug molecules, HaloTag fusion

140 evation in intracellular calcium that caused intracellular organelle dysfunction.

141 l surface growth, the biogenesis of distinct intracellular organelles, endocytosis, and the controlle

142 , the PAC channel predominantly localizes to intracellular organelles (endosomes, phagosomes, and mac

143 studies have illustrated important roles for intracellular organelles, especially mitochondria and ly

144 Mitochondria are intracellular organelles essential for cell viability an

145 on channels, attendant scaffolding proteins, intracellular organelles, extracellular proteins, and, i

146 in sequestering and redistributing Ca2(+) to intracellular organelles following Ca2(+) influx at the

147 d the ability of CDCs to directly remodel an intracellular organelle for inflammatory response.

148 Proteomics analysis of the intracellular organelle for silica biosynthesis led to t

149 and a catabolic process of self-digestion of intracellular organelles for energy use and survival in

150 which extracellular growth factors regulate intracellular organelle function, and establish a target

151 evelopments and their applications to assess intracellular organelle function.

152 nt proportionalities between cells and their intracellular organelles have been widely observed in va

153 ion of flipper probes that selectively label intracellular organelles, i.e., lysosomes, mitochondria,

154 will be approximately equal to the number of intracellular organelles if random segregation prevails.

155 ctin-rich plasma membrane ruffles into large intracellular organelles in a phosphatidylinositol 3-kin

156 transiently expressed Dm-cF was localized to intracellular organelles in D. melanogaster S2 cells, un

157 Their association with intracellular organelles in defined regions of the myocy

158 ase) is a multisubunit enzyme that acidifies intracellular organelles in eukaryotes.

159 f the ER in communicating ER stress to other intracellular organelles in MASLD pathogenesis.

160 ndings highlight the importance of different intracellular organelles in specific innate immune respo

161 was used to record ion channel activity from intracellular organelles in the presynaptic terminal of

162 Given the absence of intracellular organelles in the sub-micron diameter olfa

163 Absence of intracellular organelles in these vacuoles, shown by ele

164 on pump responsible for the acidification of intracellular organelles in virtually all eukaryotic cel

165 e a new functional role for P2X receptors on intracellular organelles, in this case in osmoregulation

166 transport reactions distributed across five intracellular organelles including cytosol, plastid, mit

167 misfolded SOD1 onto the cytoplasmic faces of intracellular organelles, including mitochondria and end

168 misfolded SOD1 onto the cytoplasmic faces of intracellular organelles, including mitochondria and the

169 Proteins typically associated with other intracellular organelles, including nuclei, mitochondria

170 and accumulation on the cytoplasmic faces of intracellular organelles, including the mitochondria and

171 nding to and imaging of exogenous TTR within intracellular organelles, including the mitochondria and

172 has been implicated in vesicle budding from intracellular organelles, including the trans-Golgi netw

173 en distinct and morphologically well-defined intracellular organelles, including three distinct types

174 hermore, the isolation of DRMs from purified intracellular organelles independently verified the loca

175 been proposed, including TWIK-1 retention in intracellular organelles, inhibition by posttranslationa

176 he aging process in the function of the main intracellular organelles involved in Ca(2+) regulation:

177 cking of membrane vesicles between different intracellular organelles involves the formation of solub

178 major lysosomal pathway for the turnover of intracellular organelles is markedly impaired in neurons

179 The rapid mobilization of intracellular organelles is regulated by vesicular traff

180 n the interactions of lysosomes with various intracellular organelles, it is not surprising that lyso

181 ecretion of von Willebrand factor (VWF) from intracellular organelles known as Weibel-Palade bodies (

182 genetic defects in proteins associated with intracellular organelles, mainly the endoplasmic reticul

183 le is a good example why length and shape of intracellular organelles matter.

184 Intracellular organelles mediate complex cellular functi

185 drop in DeltaPsim, endoplasmic reticulum and intracellular organelle membrane potential tantamount to

186 hese genes in the production and function of intracellular organelles, mice doubly homozygous for the

187 erate the forces that drive cell crawling or intracellular organelle motility.

188 arrays that stimulate protrusions and drive intracellular organelle movements.

189 pe SARS-CoV-2 E protein can be trafficked to intracellular organelles, notably the endoplasmic reticu

190 from muscle contraction to acidification of intracellular organelles, nutrient accumulation and surv

191 e remodeling, and the elimination of certain intracellular organelles occur through the exosomal path

192 s implemented with mag-indo-1 trapped in the intracellular organelles of frog skeletal muscle and val

193 ane microdomains (lipid rafts/caveolae), and intracellular organelles of living cells, both in vitro

194 ecific targeting and delivery of antigens to intracellular organelles of macrophages using Sn-ligand

195 nonpathological amyloids have been found in intracellular organelles of normal mammalian tissues sug

196 Sequestering NIS in intracellular organelles or impairing its targeting to t

197 vel hierarchical colloidal architectures and intracellular organelles or intra-organoid structures.

198 Intracellular organelle organization is conserved in euk

199 ative pathway that regulates the turnover of intracellular organelles, parasites, and long-lived prot

200 Here, we review how these intracellular organelles participate in the induction an

201 ucial role of the DGC alphadbn in regulating intracellular organelles, particularly mitochondria and

202 ation into asymmetries of cell membranes and intracellular organelles, PCP signaling coordinates morp

203 Gas vesicles are proteinaceous intracellular organelles, permeable only to gas, that en

204 sely, activation of GPR55 at the membrane of intracellular organelles promotes Ca(2+) release from ac

205 EM waves interact with membranes of intracellular organelles, proteins, and water in the MHz

206 fatty oils are generally stored in spherical intracellular organelles referred to as oleosomes that a

207 tions at the cell surface, but investigating intracellular organelles remains a challenge.

208 The role of membrane potential in most intracellular organelles remains unexplored because of t

209 localization of CSAS orthologs to different intracellular organelles represents, to our knowledge, t

210 Mitochondria were first characterized as intracellular organelles responsible for energy producti

211 Mitochondria are intracellular organelles responsible for energy producti

212 ate (S1P) can stimulate calcium release from intracellular organelles, resulting in the activation of

213 During the second division, intracellular organelles segregate specifically to sperm

214 brane, little is known about whether and how intracellular organelles sense mechanical force and the

215 the number of structures is determined in an intracellular organelle series.

216 These observations suggest that these intracellular organelles share a remarkably conserved me

217 blished the presence of Birbeck granules, an intracellular organelle specific to LCs.

218 component of the DGC, on the homeostasis of intracellular organelles, specifically mitochondria and

219 ery little fluorescent beta(2)m was found in intracellular organelles stained by DiOC(6), marking the

220 ls localized on both the plasma membrane and intracellular organelles such as endoplasmic reticulum.

221 G-protein-mediated pathways on membranes of intracellular organelles such as endosomes and the Golgi

222 unt for the presence of skeletal networks in intracellular organelles such as lysosomes, the Golgi ap

223 through the cytoplasm for eventual relay to intracellular organelles such as lysosomes.

224 o the extracellular environment, or found in intracellular organelles such as the endoplasmic reticul

225 proteins into the lipid bilayer of specific intracellular organelles such as the endoplasmic reticul

226 toskeletal remodeling but also the motion of intracellular organelles such as the nucleus.

227 t from loss of integrity of the membranes of intracellular organelles, such as mitochondria and autop

228 Intracellular organelles, such as mitochondria, are an e

229 of which are autophagy specific, as well as intracellular organelles, such as the ER and Golgi, and

230 ermeabilized cells to be present in discrete intracellular organelles, suggesting that these cells ha

231 The endoplasmic reticulum (ER) is a crucial intracellular organelle that is essential for numerous c

232 romotes abnormalities in the distribution of intracellular organelles that are correctable by pharmac

233 SignificanceBiomolecular condensates are intracellular organelles that are not bounded by membran

234 ings add autophagosomes to the collection of intracellular organelles that contribute to phagosome ma

235 Endosomes and lysosomes are key intracellular organelles that couple nutrition and metab

236 t of many rare diseases is the mitochondria, intracellular organelles that originated through endosym

237 Lipid droplets (LDs) are intracellular organelles that provide fatty acids (FAs)

238 In summary, MBsomes may sometimes serve as intracellular organelles that signal via integrin and EG

239 Lipid droplets (LDs) are intracellular organelles that store neutral lipids withi

240 However, intracellular organelles that synthesize these EV-associ

241 embranes and cause release of molecules from intracellular organelles that ultimately induces cell ne

242 sion of spermatogenesis requires specialized intracellular organelles, the fibrous body-membranous or

243 The mitochondrion is an intracellular organelle thought to originate from endosy

244 iate zinc efflux and compartmentalization in intracellular organelles; thus, ZnTs play a central role

245 oduction and/or movement of vesicles from an intracellular organelle to the cell surface to support m

246 xtracellular growth factors communicate with intracellular organelles to control lysosomal function i

247 used on the contribution of Pgp expressed in intracellular organelles to drug resistance.

248 c pH, suggesting it may also function within intracellular organelles to reduce these metals.

249 dicate that although Ca2+ release from other intracellular organelles to the cytosol is adequate for

250 nition by CTL triggers rapid polarization of intracellular organelles toward the synapse formed with

251 facilitating subcellular resolution imaging, intracellular organelle tracking, monosynaptic input map

252 brane fusion and fission, thereby regulating intracellular organelle trafficking.

253 en shown to play a role in the regulation of intracellular organelle transport .

254 Nonperturbative monitoring of intracellular organelle transport in unstained living ce

255 Certain types of intracellular organelle transport to the cell periphery

256 d in several subcellular functions involving intracellular organelle transport.

257 que properties implicate a role for HDAC6 in intracellular organelle transport.

258 M), suggesting that GLUT8 is associated with intracellular organelles under basal conditions.

259 rafficking and the formation of melanosomes, intracellular organelles unique to melanocytes and melan

260 by treatments that inhibit acidification of intracellular organelles, using chloroquine, a pH-neutra

261 The excessive acidification of intracellular organelles was corrected with low concentr

262 rion to determine the membrane properties of intracellular organelles, we found that the endocytic re

263 ed non-canonical activation of Gbetagamma at intracellular organelles, where the Golgi apparatus is a

264 aintenance of the acidic microenvironment in intracellular organelles, whereas its membrane-bound V(0

265 of vesicles that are formed from preexisting intracellular organelles, which serve as a scaffold for

266 lation of lipids and membranous materials in intracellular organelles, which was hypothesized to be c

267 es are delivered into a phagosome, a complex intracellular organelle with a well-established and impo

268 lso resided in a heterogeneous population of intracellular organelles with discrete dynamic propertie

269 ion in cell biology is how is the routing of intracellular organelles within cells regulated?

270 unwanted cytoplasmic contents and self-renew intracellular organelles without cell division to mainta