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1 t inhibition of glycosylation results in its intracellular retention.
2 ors and arrestin was not responsible for the intracellular retention.
3 contained in this domain are unnecessary for intracellular retention.
4 ma membrane of primary neurons, with minimal intracellular retention.
5  CCL5, and 2 CCL5 variants that promote CCR5 intracellular retention.
6 rface expression of K(v)7 channels via their intracellular retention.
7 ted secretion and correspondingly, increased intracellular retention.
8 as previously shown to be critical for GLUT4 intracellular retention.
9 tivation depends on EGFR internalization and intracellular retention.
10 tion of protein translation that exacerbated intracellular retention.
11 in domain of CLECSF8 was responsible for its intracellular retention.
12 he cell surface, resulting in their abnormal intracellular retention.
13 nship between vIL-6-calnexin interaction and intracellular retention.
14 G109R and R213W) secretion of mutant RS1 and intracellular retention.
15 lex-1 (AP-1) causes a delay in the return to intracellular retention after insulin withdrawal.
16 tation of the LL motif slows return to basal intracellular retention after insulin withdrawal.
17 c redistribution of Kv4.2, releasing it from intracellular retention and allowing plasma membrane exp
18 , whose product determines folate/antifolate intracellular retention and antifolate antitumor activit
19 trol from birth to P28 decreased mutant COMP intracellular retention and chondrocyte cell death, and
20 have in a dominant negative fashion, causing intracellular retention and degradation of wild-type cav
21 ding leading to an abnormal conformation and intracellular retention and elimination.
22 and provides an additional mechanism for the intracellular retention and insulin-stimulated release o
23 alpha(1D)-ARs) in most cell types results in intracellular retention and little or no functionality.
24         We examine here the requirements for intracellular retention and localization of vIL-6.
25 ellular loop (ICL3) is proposed to result in intracellular retention and loss-of-function.
26 inges of C1r and C1s and are associated with intracellular retention and mild endoplasmic reticulum e
27 isrupted, thus alleviating both D469del-COMP intracellular retention and premature chondrocyte cell d
28 ically labeled cathepsin D indicated reduced intracellular retention and processing in the knockout c
29  protein stability, induced its high partial intracellular retention, and decreased its cell surface
30 e ligand patterning on the uptake mechanism, intracellular retention, and export dynamics.
31  resistance to degradation, and its enhanced intracellular retention are the major contributing facto
32 conditions to maintain redox homeostasis and intracellular retention as a protective response during
33 budding and forming particles, and hence its intracellular retention cannot be attributed to a cytoso
34 ric and heteromeric combinations that affect intracellular retention characteristics and protein stab
35         Attachment of MDDL to VSG results in intracellular retention confirming that MDDL is a trypan
36  the precise balance between anterograde and intracellular retention elements that control the cell s
37            Whether pathogenesis results from intracellular retention, extracellular deficiency, or th
38 ssion levels both in vitro and in vivo, with intracellular retention for p.P1824H.
39         Most XLRS-associated mutations cause intracellular retention, however a subset are secreted a
40 it to the plasma membrane are susceptible to intracellular retention in HIV-1 Nef-expressing cells.
41    Both mutant transporters exhibit enhanced intracellular retention in renal cells, an observation t
42 s distinct from WT) TNFRSF1A showed abnormal intracellular retention in the neutrophils of TRAPS pati
43                                              Intracellular retention is due to phosphorylation to ade
44 borated that the information determining the intracellular retention is present within amino acid seq
45  was identified as a direct interactor of an intracellular retention motif: CLIP coupled to RNA pull-
46 monstrated the presence/function of specific intracellular retention motifs, the interacting protein/
47                        We assessed secretion/intracellular retention, multimerization, regulated stor
48 unchanged in infected cells, suggesting that intracellular retention occurred after peptide loading.
49 in Ig domains 0 and 1 (D0 and D1) causes the intracellular retention of 3DL1*004.
50  oncolysis increases over time, which limits intracellular retention of [(18)F]FHBG.
51 arboxyl terminus is the chief determinant of intracellular retention of a significant fraction of tot
52 -succinimidyl 3-iodobenzoate, SIPC increased intracellular retention of activity by up to 65%.
53 ecluded LTD and the underlying NMDAR-induced intracellular retention of AMPARs.
54 sm and H(2)O(2) production by decreasing the intracellular retention of As(2)O(3).
55                                              Intracellular retention of ATZ triggers a complex injury
56 terized p.R125C mutation, p.G257R results in intracellular retention of beta1B, generating a function
57 inting at role(s) for these complexes in the intracellular retention of CD4.
58 ow that the AP-3 complex is required for the intracellular retention of Chs3p.
59 lagen, causing VWD through dominant-negative intracellular retention of coexpressed wild-type (WT) VW
60  level was confirmed in both families by the intracellular retention of collagen XII in patient derma
61                    PSACH is characterized by intracellular retention of COMP and other extracellular
62 in MT-COMP mice reduced mTORC1 signaling and intracellular retention of COMP, and increased prolifera
63   Accumulation assays confirmed the improved intracellular retention of compound 8.
64 hat an unpaired Cys1169 does not explain the intracellular retention of Cys1149Arg.
65 on of D469del-COMP in transgenic mice causes intracellular retention of D469del-COMP, thereby recapit
66                       Here we tested whether intracellular retention of deltaR in sensory neurons con
67 ins cause MDR either by decreasing the total intracellular retention of drugs or redistributing intra
68 ated the first mouse model to show extensive intracellular retention of ECM proteins recapitulating t
69 es appear important for surface egression or intracellular retention of empty HLA-DR.
70                      IFN-gamma increased the intracellular retention of fibrillar Abeta40 and Abeta42
71 erivatives, which are the forms required for intracellular retention of folates and are also the pref
72  human embryo kidney 293 cells, resulting in intracellular retention of gamma2.
73  mutants in COS-1 cells also resulted in the intracellular retention of GPIIb-IIIa, suggesting that i
74 eplacement with Glu, Lys, Pro, or Asn caused intracellular retention of GPIIb-IIIa.
75  Raji cells promoted the internalization and intracellular retention of HIV-1.
76 munofluorescence microscopy corroborated the intracellular retention of HLA-DR and revealed markedly
77 g that disulphide bonding contributes to the intracellular retention of I AAT.
78 nslational maturation of ULBP2, resulting in intracellular retention of immature ULBP2.
79 nduced AMPAR endocytosis, it is required for intracellular retention of internalized AMPARs.
80  expression systems and primary neurons, the intracellular retention of KA2 is not caused by subunit
81 unit to both enhance inactivation and induce intracellular retention of Kv1.3.
82 rmore, TCR downmodulation is mediated by the intracellular retention of ligated complexes and degrada
83 stitution and showed that it resulted in the intracellular retention of malfolded alphaIIb beta3 hete
84      In conclusion, these data indicate that intracellular retention of mutant alpha1-ATZ is associat
85              This dysplasia results from the intracellular retention of mutant COMP protein and prema
86         Laboratory investigations documented intracellular retention of mutated alpha-galactosidase A
87 ling of mutant receptors resulted in reduced intracellular retention of occupied EGF receptors and de
88 lar peptide binding, but is not required for intracellular retention of open conformers.
89  and little efflux after paclitaxel removal; intracellular retention of paclitaxel may contribute to
90  VWF, and the mutation was proposed to cause intracellular retention of pro-VWF heterodimers.
91     Internalization assays demonstrated that intracellular retention of radioactivity was up to 1.5-f
92 To identify factors that may function in the intracellular retention of rVWFR273W, we investigated th
93 s confirmed impaired secretion and increased intracellular retention of TE, and insoluble elastin ass
94 hibition appears to be mediated by increased intracellular retention of the CCR5 coreceptor- AOP-RANT
95                       UL141 binding promotes intracellular retention of the DRs, thus protecting viru
96 t in cells becomes translated into prolonged intracellular retention of the drug.
97 de collection of yeast mutants for defective intracellular retention of the ER chaperone, Kar2p.
98 ing, it is not sufficient to account for the intracellular retention of the heterodimer.
99                                    Thus, the intracellular retention of the IRVs in adipocytes requir
100                                     Although intracellular retention of the majority of mutant matril
101 ts indicate the pathological basis of RS1 is intracellular retention of the majority of mutant protei
102 uption of the proximal region results in the intracellular retention of the MaxiK channel without aff
103  of the mutant mice were associated with the intracellular retention of the mutant DSPP in the odonto
104 l TRMA truncations are clustered resulted in intracellular retention of the mutant protein.
105 ell surface expression of ferroportin due to intracellular retention of the mutant protein.
106 ntified as mediating drug resistance, causes intracellular retention of the mutant proteins.
107 nd -4 (NL3 and NL4), respectively, result in intracellular retention of the mutant proteins.
108 fluorescence analysis demonstrated increased intracellular retention of the mutant proteins.
109 nd these changes were weakly correlated with intracellular retention of the mutant receptors.
110 brane localization of the mK44 N-termini and intracellular retention of the pore-forming C-termini.
111 GSDMD compromises this preference, hindering intracellular retention of the precursor and secretion o
112 be shown to participate in MOR export by the intracellular retention of the receptor after small inte
113  show that mutations of the rLHR which cause intracellular retention of the receptor result in a decr
114 sociated heterozygous MC4R mutations lead to intracellular retention of the receptor.
115  in misfolding of the D1 domain and complete intracellular retention of the receptor.
116 on of AS160 and Na(+),K(+)-ATPase led to the intracellular retention of the sodium pump.
117 peptidase (IRAP), and ACBD3 was required for intracellular retention of these cargos in unstimulated
118 erologous cells show that there is prolonged intracellular retention of these mutants even though the
119                                          The intracellular retention of these protein complexes is me
120 restoration of BCR-ABL signaling mediated by intracellular retention of TKIs above a quantifiable thr
121  or disruption of bile production and causes intracellular retention of toxic bile constituents, incl
122 ysosomal fusion rates after invasion and the intracellular retention of trypomastigotes.
123 h elevated HIF1alpha levels, cell death, and intracellular retention of types II and X collagen.
124 ytoplasmic domains of UL16 are important for intracellular retention of UL16, whereas the ectodomain
125 ow that tumor cell-associated CEACAM1 causes intracellular retention of various NKG2D ligands in mous
126                                   Pathogenic intracellular retention of VWF lacking exons 33-34 cause
127 tive manner, causing the mislocalization and intracellular retention of WT Cav-1.
128 CD46 down-regulation was not attributable to intracellular retention or a global or specific shutdown
129 intersection of mechanisms that include: (1) intracellular retention or degradation of VWF, (2) defec
130 t increased membrane permeability, increased intracellular retention, or modulation of melphalan's me
131 e were used to test the local absorption and intracellular retention patterns of selected probes, in
132  -3/-7 from the C terminus that functions in intracellular retention prior to assembly with other Fce
133                           In line with their intracellular retention, remaining currents of TRPC1 and
134  redistribution of this gelatinase, in which intracellular retention resulted in reciprocal extracell
135 o epilepsy through a mechanism that includes intracellular retention resulting in aberrant neuronal p
136 sociated with NKG2D(FL), which led to forced intracellular retention, resulting in decreased surface
137                                         This intracellular retention signal may preclude proper plasm
138 M1/p62 suppressed UBB(+1) secretion, causing intracellular retention: SQSTM1/p62 knockout led to UBB(
139 he abundance of aquaporin 2 and enhanced its intracellular retention, suggesting impaired sensitivity
140                   Some mutations resulted in intracellular retention, suggesting that the receptors w
141 , we decided to use 111In, which has greater intracellular retention than iodine.
142 nd analyses of Clr-a/Clr-f hybrids attribute intracellular retention to both the stalk region and par
143 se decreased Ca(2+) sensitivity or increased intracellular retention, traits that would not easily ex
144 estricted pool of peptides, resulting in its intracellular retention under normal conditions.
145  by which different ligands promote receptor intracellular retention versus presence on the cell memb
146            To understand what governs mutant intracellular retention, we generated a series of R345 m
147 PrP; this indicates that both misfolding and intracellular retention were required to induce the tran
148 h of the mutant proteins exhibit substantial intracellular retention when expressed in mammalian rena
149 s, FABP binding of EETs may facilitate their intracellular retention whereas the lack of FABP affinit
150 S is associated with a defect in biogenesis, intracellular retention, which is similar to but milder
151 86 in 3DL1*004 is the principal cause of its intracellular retention, with a secondary and additive c

 
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