ライフサイエンスコーパス: intracellular signaling molecule

1 ts, ERK was the most significantly activated intracellular signaling molecule.

2 development because the ET(A) receptor is an intracellular signaling molecule.

3 Calcium is a universal intracellular signaling molecule.

4 paradigm for the specific recruitment of an intracellular signaling molecule.

5 Protein kinase C is an important intracellular signaling molecule.

6 KCNE accessory subunits and by an important intracellular signaling molecule.

7 Cyclic diguanylate (c-di-GMP) is a bacterial intracellular signaling molecule.

8 through membrane-bound receptors and related intracellular signaling molecules.

9 ects occur in part via Nef interactions with intracellular signaling molecules.

10 ds on the concentrations and localization of intracellular signaling molecules.

11 specific targeting of Vav and other critical intracellular signaling molecules.

12 n multiple stimuli, including the binding of intracellular signaling molecules.

13 ation; however, each cytokine uses different intracellular signaling molecules.

14 raction of integrin cytoplasmic domains with intracellular signaling molecules.

15 lyphosphoinositides, the lipid precursors of intracellular signaling molecules.

16 he spatiotemporal patterning and function of intracellular signaling molecules.

17 cies (ROS) released from the mitochondria as intracellular signaling molecules.

18 s high or low temperatures, and a variety of intracellular signaling molecules.

19 xpression and ability to form complexes with intracellular signaling molecules.

20 d receptor tyrosine kinases and dysregulated intracellular signaling molecules.

21 r that interacts with numerous receptors and intracellular signaling molecules.

22 ng as adaptors for various transmembrane and intracellular signaling molecules.

23 the cytoplasmic tails of the integrins with intracellular signaling molecules.

24 neurotrophic factor receptors and downstream intracellular signaling molecules.

25 nd stabilization of many protein kinases and intracellular signaling molecules.

26 ed by coordinate interactions among multiple intracellular signaling molecules.

27 rotein kinases, steroid receptors, and other intracellular signaling molecules.

28 ed by autophosphorylation and recruitment of intracellular signaling molecules.

29 enoids, which serve as lipid attachments for intracellular signaling molecules.

30 Anti-pS609 inhibited GPIb-IX binding to the intracellular signaling molecule, 14-3-3zeta.

31 of transcription 3 (STAT3) is the principal intracellular signaling molecule activated upon G-CSF li

32 ween an epigenetic regulator, WHSC1, and key intracellular signaling molecules, AKT, RICTOR, and Rac1

33 It is proposed to act as an intracellular signaling molecule and can serve as the ca

34 The ability of TLRs to engage different intracellular signaling molecules and cross-talk with ot

35 hermore, VEGF-A-dependent phosphorylation of intracellular signaling molecules and endothelial prolif

36 en species (ROS) are recognized as important intracellular signaling molecules and have been implicat

37 Reactive oxygen species (ROS) act as intracellular signaling molecules and initiate apoptosis

38 ine (DA) receptors exert opposing actions on intracellular signaling molecules and often have dispara

39 ned, and flow cytometry was applied to stain intracellular signaling molecules and surface receptors.

40 lates the expression and activity of several intracellular signaling molecules and transcription fact

41 as a result of variegated surface receptor, intracellular signaling molecule, and transcription fact

42 ranscription factors, cell-surface proteins, intracellular signaling molecules, and modifiers of the

43 hat include specific cell-surface receptors, intracellular signaling molecules, and nuclear transcrip

44 ns between Trk receptor tyrosine kinases and intracellular signaling molecules are dictated both by p

45 d potentiation and rule out interaction with intracellular signaling molecules as a mechanism of comp

46 FcRgamma) and signals using many of the same intracellular signaling molecules as immune receptors.

47 These results implicate polyamines, emerging intracellular signaling molecules, as potential physiolo

48 C enzymes, in contrast, are regulated by the intracellular signaling molecules bicarbonate and calciu

49 se group behaviors are regulated by both the intracellular signaling molecule c-di-GMP and acylhomose

50 We also observe that another intracellular signaling molecule, Ca(2+), stimulates RAG

51 mate receptors mGluR1alpha and mGluR2/3; the intracellular signaling molecules calcineurin and calciu

52 s mGluR1alpha, mGluR2/3, and mGluR5; and the intracellular signaling molecules calcineurin, calcium c

53 IL-22 (rIL-22) enhances the expression of an intracellular signaling molecule, calgranulin A.

54 Moreover, we identified a novel intracellular signaling molecule, cAMP-response element

55 e cell corpse engulfment pathway mediated by intracellular signaling molecules CED-2 (homologous to t

56 R-B) and stimulates marked elevations of the intracellular signaling molecule, cGMP.

57 Identification of intracellular signaling molecules controlling this chann

58 Calcium, a ubiquitous intracellular signaling molecule, controls a diverse arr

59 These data position CD2AP as a major intracellular signaling molecule coordinating NGF signal

60 h the development of fluorescent sensors for intracellular signaling molecules coupled with improved

61 The intracellular signaling molecule cyclic di-GMP (c-di-GMP

62 rved for strains with elevated levels of the intracellular signaling molecule cyclic di-GMP (c-di-GMP

63 zed in this study is increased levels of the intracellular signaling molecule cyclic di-GMP (c-di-GMP

64 ator of biofilm formation in bacteria is the intracellular signaling molecule cyclic diguanylate (c-d

65 The intracellular signaling molecule cyclic-di-GMP (c-di-GMP

66 The intracellular signaling molecule, cyclic-di-GMP (c-di-GM

67 tol phosphates are a family of water-soluble intracellular signaling molecules derived from membrane

68 Very few studies addressed how intracellular signaling molecules differentially specify

69 lr), Apolipoprotein receptor 2 (Apoer2), and intracellular signaling molecule Disabled-1 (Dab1).

70 an extracellular protein, Reelin (Reln), an intracellular signaling molecule, Disabled-1 (Dab1), and

71 The intracellular signaling molecule Dishevelled (Dvl) media

72 Arhgef1 is an intracellular signaling molecule expressed by myeloid ce

73 Thus, afadin is a key intracellular signaling molecule for cadherin recruitmen

74 a specific ROS, superoxide anion, acts as an intracellular signaling molecule for RGC death after axo

75 olecule-associated protein (SAP), a critical intracellular signaling molecule for T-B lymphocyte inte

76 tor-associated kinases (IRAKs) are essential intracellular signaling molecules for transduction of TL

77 kin disease (45 cases and 3 cell lines) of 5 intracellular signaling molecules found in B cells.

78 own that Sod2 also serves as a source of the intracellular signaling molecule H(2)O(2).

79 abolites and are also thought to function as intracellular signaling molecules; however, the direct e

80 sis of inositol hexakisphosphate (IP(6)), an intracellular signaling molecule implicated in the regul

81 kinases (MAPKs), ERK1 and ERK2, are critical intracellular signaling molecules important for transduc

82 Cyclic GMP (cGMP) is an important intracellular signaling molecule in the cardiovascular s

83 Reactive oxygen species (ROS) function as intracellular signaling molecules in a diverse range of

84 CTGF rapidly activates several intracellular signaling molecules in human mesangial cel

85 Since sHSP are known to be regulated by many intracellular signaling molecules in other cells types o

86 Therefore, we examined the role of these intracellular signaling molecules in our primary neurona

87 plasmic proteins that associate with several intracellular signaling molecules in regulation of vario

88 ed reorganization of the T cell membrane and intracellular signaling molecules in response to T cell

89 3 is a scaffolding protein, integrating many intracellular signaling molecules in specialized areas c

90 ine kinase inhibitors to examine the role of intracellular signaling molecules in Stx-mediated cytoki

91 st that PI(4,5)P2 and/or PI(4)P may serve as intracellular signaling molecules in these primary senso

92 However, ROS can also act as intracellular signaling molecules in vascular cells.

93 eading edges of pseudopods; 2) activation of intracellular signaling molecules including focal adhesi

94 d has been reported to interact with various intracellular signaling molecules including the epiderma

95 nal transduction is mediated by a complex of intracellular signaling molecules including TRADD, TRAF2

96 DOKL contains features of intracellular signaling molecules, including an N-termin

97 mulates breast tumorigenesis via a number of intracellular signaling molecules, including PI3K/AKT an

98 lation and translocation into the nucleus of intracellular signaling molecules, including Smad1, Smad

99 eptor in cells results in activation of many intracellular signaling molecules, including transcripti

100 ion factors, neurotransmitter receptors, and intracellular signaling molecules induced by repeated co

101 This suggests that Rac1 is an important intracellular signaling molecule involved in a spinal de

102 Ras is an intracellular signaling molecule involved in cell prolif

103 mitogen-activated protein kinase, is a major intracellular signaling molecule involved in inflammatio

104 cellular signal-regulated kinase (ERK) is an intracellular signaling molecule involved in nucleus acc

105 Mitogen-activated protein kinases (MAPK) are intracellular signaling molecules involved in cytokine s

106 However, the downstream intracellular signaling molecules involved in the develo

107 There is static information on the intracellular signaling molecules involved in these resp

108 It is not clear which intracellular signaling molecule is responsible for this

109 activated protein (MAP) kinase, an important intracellular signaling molecule, is activated in the gl

110 critical role in processing information from intracellular signaling molecules, is capable of undergo

111 n (SAP), an src homology 2 domain-containing intracellular signaling molecule known to interact with

112 pe II receptors to induce phosphorylation of intracellular signaling molecules known as Smads.

113 The expression of Grb, Ras, Raf, and Erk, intracellular signaling molecules known to be downstream

114 Ceramides have emerged as intracellular signaling molecules linked to tumorigenesi

115 or cells and CSCs, and the concentrations of intracellular signaling molecules (NFkB, Bcl-2, BAX).

116 The development of methods to analyze intracellular signaling molecules on microarrays would m

117 Several genes encoding either intracellular signaling molecules or neurotransmitter re

118 at the P2X7 receptor may also activate other intracellular signaling molecules or other ion channels.

119 transforms by binding to and activating key intracellular signaling molecules, phosphatidylinositol

120 ription in vivo can be mimicked by using the intracellular signaling molecule potassium glutamate in

121 cAMP, the intracellular signaling molecule produced in response to

122 ore than 90 other binding partners including intracellular signaling molecules, receptors, ion channe

123 hosphorylation by activated receptors, these intracellular signaling molecules recruit various downst

124 involves receptor-ligand pair clustering and intracellular signaling molecule recruitment with a coin

125 and how labile zinc ion (Zn(2+)) acts as an intracellular signaling molecule remains unclear.

126 This report implicates calcineurin as an intracellular signaling molecule responsible for immune

127 ) is characterized by underexpression of the intracellular signaling molecule RhoH.

128 e at will the levels or activity of specific intracellular signaling molecule(s) in specified cells w

129 the TGF-beta type I receptor (ALK-5) and its intracellular signaling molecule Smad3 were necessary fo

130 TGFBIp also induced phosphorylation of intracellular signaling molecules SRC, FAK, AKT, JNK and

131 owth factor-beta, which was dependent on the intracellular signaling molecule STAT1 but was independe

132 LPS-induced activation of intracellular signaling molecules, STAT1 Tyr-701, STAT1

133 Phosphorylation of proto-oncogenic intracellular signaling molecules Stat3, Erk1/2, and P38

134 ing prenylation of RhoA and effects on other intracellular signaling molecules such as NF-kappaB and

135 tant posttranslational lipid attachments for intracellular signaling molecules such as the Rho GTPase

136 thus they initiate signaling by interacting intracellular signaling molecules such as TNFR associate

137 Spatiotemporal regulation of intracellular signaling molecules, such as the 3',5'-cyc

138 eta through the timed activation of discrete intracellular signaling molecules, suggesting pathways i

139 (2)) is increasingly being appreciated as an intracellular signaling molecule that affects inflammato

140 One intracellular signaling molecule that integrates converg

141 is a SRC-homology-2 (SH2) domain-containing intracellular signaling molecule that is required for T

142 These findings demonstrate that GBDR1 is an intracellular signaling molecule that may play a role in

143 nosine monophosphate (c-di-GMP) is a dynamic intracellular signaling molecule that plays a central ro

144 rotein (WASP), a hematopoietic cell-specific intracellular signaling molecule that regulates the acti

145 in a deficiency of ARHGEF1, a hematopoietic intracellular signaling molecule that transmits signals

146 kinases (MAPKs; also known as ERKs) are key intracellular signaling molecules that are ubiquitously

147 accompanied by up-regulation of several key intracellular signaling molecules that critically regula

148 pha, beta, gamma, and delta, are a family of intracellular signaling molecules that play important ro

149 1 and -2 (Barr1 and Barr2, respectively) are intracellular signaling molecules that regulate many imp

150 now permit spatial distributions of specific intracellular signaling molecules to be observed in real

151 to delineate cell types simultaneously with intracellular signaling molecules to measure biological

152 s) by various contractile agonists activates intracellular signaling molecules to result in an increa

153 The intracellular signaling molecule TRAF6 is critical for T

154 ivator of NF-kappaB), which recruits various intracellular signaling molecules via specific motifs in

155 ulation in the acute phase of TBI, levels of intracellular signaling molecules were assessed followin

156 We found that these intracellular signaling molecules were complexed with P-

157 Genotoxic stresses activate intracellular signaling molecules, which lead to growth

158 Intracellular signaling molecules, which negatively regu

159 TMS1/ASC is an intracellular signaling molecule with proposed roles in

160 as ASC and PYCARD, TMS1 encodes a bipartite intracellular signaling molecule with proposed roles in

161 in cyclic adenosine monophosphate (cAMP), an intracellular signaling molecule with several known rest

162 kage between a GPI-anchored receptor and the intracellular signaling molecules with which it is physi