ライフサイエンスコーパス: intracellular transport

1 variants both in surface mobility and during intracellular transport.

2 organelle encounter dynamics in noncanonical intracellular transport.

3 ng provide rich information on mechanisms of intracellular transport.

4 in protein turnover, cellular signaling, and intracellular transport.

5 as DNA replication, RNA/protein synthesis or intracellular transport.

6 a key pathway for cell polarization through intracellular transport.

7 for mitosis, maintenance of cell shape, and intracellular transport.

8 ent processes such as muscle contraction and intracellular transport.

9 namics of the cytoskeleton morphology during intracellular transport.

10 hedding new light on unresolved questions in intracellular transport.

11 of downstream signaling by integrins reduced intracellular transport.

12 vities to promote membrane tubulation during intracellular transport.

13 fect on particle morphology nor nanoparticle intracellular transport.

14 cargo they tow as part of microtubule-based intracellular transport.

15 , which serve as tracks for myosin-dependent intracellular transport.

16 nelles and an arborized system of tracks for intracellular transport.

17 s utilize a cytoskeleton for their entry and intracellular transport.

18 s regarding the role of motor cooperation in intracellular transport.

19 mone hypothesis for cell entry and HSP70 for intracellular transport.

20 actively stabilizes the Tg dimer complex for intracellular transport.

21 n, endosomal release, carrier unpacking, and intracellular transport.

22 ubule motor kinesin-1 plays central roles in intracellular transport.

23 racterization of their attachment, entry and intracellular transport.

24 of determining the directions and speeds of intracellular transport.

25 eins that, among other functions, facilitate intracellular transport.

26 sses including cell division, migration, and intracellular transport.

27 ation, complex assembly and disassembly, and intracellular transport.

28 association with other proteins involved in intracellular transport.

29 d changes in cytoskeletal dynamics influence intracellular transport.

30 al nervous system and has been implicated in intracellular transport.

31 -induced changes in MT levels facilitate its intracellular transport.

32 irus for an intact actin cytoskeleton during intracellular transport.

33 microtubule-based motor proteins that power intracellular transport.

34 as single or few molecules, as characterizes intracellular transport.

35 d processes, including molecular motor-based intracellular transport.

36 X domain is a suitable mechanical anchor for intracellular transport.

37 olecular motors and lipids interact to drive intracellular transport.

38 probe to examine their clustering states and intracellular transport.

39 gos during clathrin-mediated endocytosis and intracellular transport.

40 of microtubule dynamics, cell migration, and intracellular transport.

41 g alpha- or beta-structure that enable their intracellular transport.

42 sed functions such as muscle contraction and intracellular transport.

43 up-regulated genes involved in apoptosis and intracellular transport.

44 inesin-2 that is best known for its roles in intracellular transport.

45 otentially be used as a noninvasive probe of intracellular transport.

46 Knockdown of bbs3 in zebrafish alters intracellular transport, a phenotype observed with knock

47 ryptococcus neoformans is thought to rely on intracellular transport, a process not fully explored in

48 o investigate further the role of A27 in IMV intracellular transport, a recombinant vaccinia virus wa

49 n microfluidic configurations stress-induced intracellular transport across the lipid membrane can be

50 ction induces a global blockage of host cell intracellular transport, affecting the exchange between

51 olding of the heavy chain, while the rate of intracellular transport after assembly is unaffected.

52 lations, is able to efficiently avoid active intracellular transport along microtubules, and the subs

53 ic cells rely on long-lived microtubules for intracellular transport and as compression-bearing eleme

54 te if basic amino acids in MA play a role in intracellular transport and capsid-membrane interactions

55 in is a microtubule-based motor required for intracellular transport and cell division.

56 mation required for cytoskeletal remodeling, intracellular transport and cell locomotion.

57 KIF21B is a kinesin protein that promotes intracellular transport and controls microtubule dynamic

58 f self-quenched endocytic cargo to image the intracellular transport and degradation of endocytic car

59 c peptide binding to alphabetaI early during intracellular transport and demonstrate that proteolysis

60 particular, we emphasize how the activation, intracellular transport and downstream metabolism of fat

61 We find that intracellular transport and force output by monomeric mo

62 Not only were well-known active intracellular transport and free diffusion observed, but

63 estion (Ssa2128-132A3) significantly reduced intracellular transport and fungicidal activity of Hst 5

64 g protein for Rab11, a GTPase that regulates intracellular transport and has specific roles in endoso

65 Yet, the implications of this strategy on intracellular transport and in vivo biodistribution rema

66 Motor-based intracellular transport and its regulation are crucial t

67 ify mutations that have a critical effect on intracellular transport and its regulation using mutagen

68 lar functions including shape determination, intracellular transport and locomotion.

69 n cables, which provide polarized tracks for intracellular transport and maintain defined lengths whi

70 scovery of roles for arginine methylation in intracellular transport and mRNA splicing has focused at

71 processes, including synaptic transmission, intracellular transport and neuronal transcription.

72 processive molecular motors are critical for intracellular transport and organization, yet coordinati

73 suggest a novel role for Pk2 in directional intracellular transport and our analyses show that PCP a

74 is known to interact with APP and affect its intracellular transport and processing.

75 Myoglobin binds O(2,) facilitates its intracellular transport and serves as a controller of ni

76 important role in the spatial regulation of intracellular transport and signal transduction processe

77 e rigidity of cell membranes and controlling intracellular transport and signal transduction.

78 evels of Rab3a and Rab5 proteins involved in intracellular transport and sorting of nerve growth fact

79 evels of Rab3a and Rab5 proteins involved in intracellular transport and sorting of nerve growth fact

80 Here we characterize the intracellular transport and steady-state motor subunit c

81 Intracellular transport and surface display of integral

82 a protein associated with microtubule-based intracellular transport and synapse function.

83 Taken together, these results show that the intracellular transport and TGN localization of UL11 is

84 s that efficiency and consistency of passive intracellular transport and the related anomalous scalin

85 rane by an as yet unknown mechanism, undergo intracellular transport and then fuse with lysosomes, en

86 termines the spatial scale of organelles and intracellular transport and thereby affects biosynthesis

87 Intracellular transport and trafficking kinetics of the

88 me of membranes in the cell while optimizing intracellular transport and trafficking.

89 ansport-III (ESCRT-III) and is essential for intracellular transport and vacuole biogenesis.

90 that GRP94 knockdown cells are defective in intracellular transport and, consequently, negatively im

91 etter understand the motions contributing to intracellular transport and, more generally, the means f

92 tropic effect on growth, normal cytokinesis, intracellular transports and the production of several v

93 ication and transcription, DNA supercoiling, intracellular transport, and ATP synthesis.

94 karyotic functions, including cell division, intracellular transport, and brain development.

95 elated with increased microtubule stability, intracellular transport, and ciliary assembly, yet a mec

96 required for normal expression, processing, intracellular transport, and incorporation into virions

97 served including cytoskeletal rearrangement, intracellular transport, and interferon signaling.

98 pathways beginning with the cellular uptake, intracellular transport, and localization imposes distin

99 s of APP in neuronal development, signaling, intracellular transport, and other aspects of neuronal h

100 MTs) are essential for cell division, shape, intracellular transport, and polarity.

101 ortance of the STRA6 protein for the uptake, intracellular transport, and processing of retinol by th

102 ses, including cell motility, cell division, intracellular transport, and regulation of the microtubu

103 has a central role in morphology, migration, intracellular transport, and signaling.

104 ental processes including neurite outgrowth, intracellular transport, and synapse formation and plast

105 eared to be defective at an earlier stage of intracellular transport; and the remaining mutant (K33A

106 orks driving cell motility, endocytosis, and intracellular transport are assembled in seconds by the

107 conditions in which protein synthesis and/or intracellular transport are compromised.

108 influence of dynamic cytoskeletal states on intracellular transport are investigated in Dictyosteliu

109 are essential for cell shape, division, and intracellular transport are valid targets for anticancer

110 escence microscopy studies of virus particle intracellular transport, as a brighter particle will imp

111 r assays allow us to propose a framework for intracellular transport based on the binding by kinesin-

112 n, which is known to disrupt dynein-mediated intracellular transport, blocked TGFbeta-stimulated nucl

113 nelles and are a substrate for long-distance intracellular transport, but the functional linkages bet

114 e the force of actin polymerization to drive intracellular transport, but the role of actin in endocy

115 sin and dynein are fundamental components of intracellular transport, but their interactions when sim

116 Kinesin motor proteins drive intracellular transport by coupling ATP hydrolysis to co

117 n ideal model to study nuclear migration and intracellular transport by dynein and kinesin owing to i

118 large multisubunit complex, is required for intracellular transport by dynein; however, its cellular

119 tion, which impairs parasite viability after intracellular transport by LIT1.

120 These findings advance the understanding of intracellular transport by revealing how the coordinatio

121 folylpolyglutamate synthetase (FPGS) but not intracellular transport by the reduced folate carrier.

122 There is also evidence that cells regulate intracellular transport by tuning the number and/or rati

123 ality SPORT technique, the microtubule-based intracellular transport can be unambiguously identified

124 , cilia and flagella, and provide tracks for intracellular transport--can be highly bent by intracell

125 in many cell biological pathways, including intracellular transport, cell architecture, and primary

126 ian TULP1-4 proteins play essential roles in intracellular transport, cell differentiation, signaling

127 y of cytoplasmic dynein, a motor involved in intracellular transport, cell division, and neurodevelop

128 , and promise new possibilities for studying intracellular transport, cell motility, and neuronal phy

129 les throughout eukaryotic biology, including intracellular transport, cell motility, cell division, d

130 skeleton plays an essential role in mitosis, intracellular transport, cell shape, and cell migration.

131 cal cellular and metabolic functions such as intracellular transport, cell signalling and protein tur

132 potential for exogenously added pDNA to bind intracellular transport cofactors may enhance the potenc

133 stabilizing oligomerization tags to maintain intracellular transport competence and F-triggering acti

134 retains its complete enzymatic activity and intracellular transport competence in the presence of th

135 ZFRPGR2 knockdown also resulted in an intracellular transport defect affecting retrograde but

136 Chemical inhibition of intracellular transport demonstrated that Golgi localiza

137 lternative explanation for observations that intracellular transport depends weakly on kinesin number

138 and can therefore function as a regulator of intracellular transport dynamics.

139 ALIX complex formation as a prerequisite for intracellular transport enabling viral capsid disassembl

140 within the Br module (cellular respiration, intracellular transport, energy coupled proton transport

141 usly, confocal microscopy colocalization and intracellular transport experiments strongly suggested d

142 Neuronal microtubules support intracellular transport, facilitate axon growth, and for

143 lament bundles nucleated by formins, mediate intracellular transport for cell polarity establishment

144 Eukaryotic cells use microtubule-based intracellular transport for the delivery of many subcell

145 onent genes and the activation of genes with intracellular transport functions in cultured adult NSCs

146 everity of lysosomal tug-of-wars among other intracellular transport functions involving high force.

147 f shielding against neutralizing antibodies, intracellular transport, G-F interactions, cell-cell fus

148 Protein-directed intracellular transport has not been observed in bacteri

149 zation of kinesin motors is not required for intracellular transport; however, it enables motor-to-mo

150 l VP26-mCherry fusion for the study of viral intracellular transport.IMPORTANCE Alphaherpesviruses ar

151 nhibitors of the microtubule network reduced intracellular transport in both cell types, but movement

152 axons and dendrites defines the direction of intracellular transport in neurons.

153 Intracellular transport in plant cells occurs on microtu

154 oles in establishing polarity and regulating intracellular transport in post-mitotic cells.

155 thod for resolving heterogeneous behavior of intracellular transport in space and time.

156 These findings reveal the importance of intracellular transport in steady-state lymph formation

157 ates for the first time a functional role of intracellular transport in the optimal loading of MHC cl

158 eral molecules that mediate lipid uptake and intracellular transport, including fatty-acid-binding pr

159 ost cell via the endocytic route, during its intracellular transport inside endosomes.

160 Intracellular transport involves the regulation of micro

161 Active intracellular transport is a central mechanism in cell b

162 Intracellular transport is a complex interplay of ballis

163 by interfering with cardiac contraction and intracellular transport is a dense microtubule network s

164 a broadly applicable tool for systems where intracellular transport is a key molecular mechanism.

165 Intracellular transport is an essential function in euca

166 Intracellular transport is essential for cytoplasm organ

167 Intracellular transport is essential for maintaining pro

168 Intracellular transport is facilitated by aquaporins and

169 Intracellular transport is largely driven by processive

170 Intracellular transport is mediated by molecular motors

171 in order to deliver their genome, and their intracellular transport is not fully understood.

172 Intracellular transport is predominantly heterogeneous i

173 Intracellular transport is typically bidirectional, cons

174 dies on the three major families involved in intracellular transport (kinesin-1, kinesin-2, and kines

175 e determinants in the cargo proteins and the intracellular transport machineries.

176 An efficient vectorial intracellular transport machinery depends on a well-esta

177 rt the first nonpeptide moiety that recruits intracellular transport machinery for nuclear targeting.

178 question in cell biology is how the general intracellular transport machinery is adapted to perform

179 represent novel alleles of components of the intracellular transport machinery: specifically, kinesin

180 The importance of such intracellular transport mechanisms is underscored by the

181 to experimental and theoretical analyses of intracellular transport mechanisms.

182 ng that numerous gene transcripts related to intracellular transport, mitochondria and the cytoskelet

183 accommodate ever-changing cellular needs for intracellular transport, morphogenesis, and migration.

184 ion (e.g., RNA polymerases and ribosomes) to intracellular transport (motor proteins such as kinesins

185 models, C-terminus-truncated DISC1 disrupts intracellular transport, neural architecture and migrati

186 lipid interactions, NaPCCP could function in intracellular transport of 120K in pollen tubes.

187 st roles for beta-arrestins in mediating the intracellular transport of a 7TMR to its obligate subcel

188 Unlike surface mobility, intracellular transport of betaNrxn(+) STVs was faster t

189 ding protein (hI-BABP) has a key role in the intracellular transport of bile salts.

190 rect and reciprocal space to investigate the intracellular transport of branched gold nanostars (GNSs

191 Intracellular transport of cargo particles is performed

192 Intracellular transport of cargos along microtubules is

193 Intracellular transport of cargos, including many viruse

194 vement of a cyclophilin in the regulation of intracellular transport of CD147.

195 Nervous system function requires intracellular transport of channels, receptors, mRNAs, a

196 The intracellular transport of cholesterol from the PM to th

197 The intracellular transport of cholesterol is subject to tig

198 e transporter G1 (ABCG1) plays a role in the intracellular transport of cholesterol.

199 V (MyoV) motors have been implicated in the intracellular transport of diverse cargoes including ves

200 downregulated genes related to synthesis and intracellular transport of FA, synthesis of triglyceride

201 n most abundant in liver, is associated with intracellular transport of fatty acids, nuclear signalin

202 Intracellular transport of Hst 5 was significantly impai

203 The intracellular transport of human immunodeficiency virus

204 The utility of polyamines as vectors for the intracellular transport of iron chelators is further des

205 fect in neurons by causing the disruption of intracellular transport of key organellar cargo, such as

206 ter and binding proteins, and are capable of intracellular transport of long-chain FA.

207 tion of translated SR-B1 via reduced binding/intracellular transport of Lp(a).

208 Intracellular transport of membrane organelles occurs al

209 Clathrin-coated vesicles mediate sorting and intracellular transport of membrane-bound proteins.

210 l to study the distribution and mechanism of intracellular transport of Merlin and its mutants.

211 eacts with membrane phospholipids, enhancing intracellular transport of metals.

212 uggest that LFABP functions in the efficient intracellular transport of MG.

213 CPV reduced surface levels and inhibited the intracellular transport of MHC I early during infection.

214 MPV did not interfere with MHC expression or intracellular transport of MHC molecules.

215 Intracellular transport of motor-driven cargo faces the

216 suggesting that there was an increase in the intracellular transport of MVBs to the cell periphery by

217 Intracellular transport of organelles and proteins is dr

218 data suggest that SFC is required for normal intracellular transport of PIN1 from the plasma membrane

219 , an important process in the activation and intracellular transport of proteins vital for a wide var

220 Intracellular transport of proteins, their translocation

221 belongs to a family of proteins involved in intracellular transport of receptors to the plasma membr

222 Intracellular transport of recombinant adeno-associated

223 oated vesicles provide a major mechanism for intracellular transport of select cargo, which may be so

224 y and subcellular membrane fractionation the intracellular transport of silaffin Sil3.

225 that the rapid cellular uptake kinetics and intracellular transport of SNAs stem from the arrangemen

226 Current models for the intracellular transport of Tau protein suggest motor pro

227 olvement of an unconventional pathway in the intracellular transport of TGBp3.

228 Through direct binding, Ii also directs intracellular transport of the class II major histocompa

229 iciently blocking proteolytic processing and intracellular transport of the envelope protein.

230 SSP is critical for intracellular transport of the GPC complex to the cell s

231 d at a subsequent step by blocking efficient intracellular transport of the virus.

232 The intracellular transport of these receptors has tradition

233 We demonstrate intracellular transport of this peptide, its binding and

234 e investigate how these mutations affect the intracellular transport of TREM2.

235 ne of the engineered UL20 mutations affected intracellular transport of UL20p to trans-Golgi network

236 In bacteria, ParABS systems mediate intracellular transport of various cargos, including chr

237 ein is the motor protein responsible for the intracellular transport of various organelles and other

238 on of the polyamine backbone as a vector for intracellular transport of various pharmacophores has fo

239 Intracellular transport of vesicles and organelles along

240 ctures that serve as tracks for myosin-based intracellular transport of vesicles and organelles in bo

241 r proteins are involved in cell division and intracellular transport of vesicles and organelles, and

242 s system is dependent upon the long-distance intracellular transport of viral particles in axons.

243 somes have been identified as a platform for intracellular transport of viral RNA (vRNA).

244 roteins, not only play a central role in the intracellular transport of virus particles but also regu

245 Intracellular transport of virus particles in neurons is

246 tical for proper protein oligomerization and intracellular transport or for membrane fusion triggerin

247 o elucidate the mechanisms that regulate the intracellular transport or trafficking of hERG, because

248 motors and polymer ratchets as they mediate intracellular transport, organelle dynamics, cell locomo

249 echanism can control a biochemically complex intracellular transport pathway.

250 The study of intracellular transport pathways at epithelial cell barr

251 illuminated an important role for defects in intracellular transport pathways to lysosomes.

252 min function in membrane fission in distinct intracellular transport pathways, but whether their func

253 ctor (ARF) family of small GTPases initiates intracellular transport pathways.

254 LDH7A1 coordinates a broad inhibition of the intracellular transport pathways.

255 organization, cell biogenesis, development, intracellular transport, phospholipid metabolism, protei

256 Regulation of intracellular transport plays a role in a number of proc

257 Intracellular transport plays an essential role in maint

258 argoes are resolved accurately to render the intracellular transport process in live cells.Distinguis

259 tion in the fly eye and disrupts fundamental intracellular transport processes that are likely to con

260 irus that enters neuronal cells and utilizes intracellular transport processes to establish infection

261 propose this dependence has implications for intracellular transport processes, especially for bidire

262 S-nitrosylation reactions that can regulate intracellular transport processes.

263 We conclude that ClC-3 is primarily an intracellular transport protein that is transiently inse

264 y tunable and have more substantial roles in intracellular transport regulatory mechanisms compared w

265 Intracellular transport relies on multiple kinesins, but

266 uired for entry, membrane translocation, and intracellular transport remain to be elucidated.

267 he extent to which motor copy number affects intracellular transport remains controversial.

268 owever, whether dimerization is required for intracellular transport remains unknown.

269 Functions, like signaling and intracellular transport, require the abilities to bind t

270 interferes with at least two steps in Pmel17 intracellular transport, resulting in defects in melanos

271 ane fusion, but assigning SNAREs to specific intracellular transport routes is challenging with curre

272 Kinesin motor proteins that drive intracellular transport share an overall architecture of

273 echanosensors in diverse functions including intracellular transport, signaling, cell migration, musc

274 Spindly-like motifs in adaptors involved in intracellular transport suggests a common mechanism for

275 mate receptor - prominently regulating early intracellular transport, synaptic targeting and anchorin

276 The intracellular transport system in neurons is specialized

277 their overall organization, regulation, and intracellular transport that both facilitate and modulat

278 improved toolbox for optogenetic control of intracellular transport that optimizes cellular responsi

279 sin-1 is a dimeric motor protein, central to intracellular transport, that steps hand-over-hand towar

280 d surface expression, indicating a defect in intracellular transport, though this mutation had no eff

281 l flow strength or flow channel geometry for intracellular transport through a MS channel.

282 al toxins are believed to undergo retrograde intracellular transport through the Golgi apparatus to t

283 anging from structural to enzymatic and from intracellular transport to chaperones, have been describ

284 ce proteins on Candida albicans, followed by intracellular transport to cytoplasmic effectors leading

285 ecessitates mechanism(s) to facilitate their intracellular transport to metabolic enzymes.

286 tial for a variety of processes ranging from intracellular transport to muscle contraction.

287 increasingly common in studies ranging from intracellular transport to the movements of whole organi

288 (Lis1) is a key cofactor for dynein-mediated intracellular transport towards the minus-ends of microt

289 insights into the functional constraints on intracellular transport under which cells have evolved c

290 Intracellular transport undergoes remodeling upon cell d

291 of a multi-modular protein whose function in intracellular transport underlies the growth, differenti

292 Fusion of intracellular transport vesicles requires soluble N-ethy

293 nnel is delivered to the plasma membrane via intracellular transport vesicles, it remains localized a

294 hesizing that mutant COPA leads to defective intracellular transport via coat protein complex I (COPI

295 Intracellular transport via processive kinesin, dynein,

296 Intracellular transport via the microtubule motors kines

297 K (1), a surrogate biomarker for (18)F-FGln intracellular transport, was the kinetic rate constant t

298 o probe the forces exerted on cargoes during intracellular transport, we examined latex beads phagocy

299 ly in T. brucei, at least 30 are involved in intracellular transport, whereas fewer than eight are li

300 d GTPase Rab8 plays an important role in the intracellular transport, while we have previously shown