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1 oducing a potential novel model of autocrine/intracrine action of S1P that still involves its GPCRs.
2 n-coupled PTH/PTHrP receptor, PTHrP also has intracrine actions mediated by a nuclear localization se
3 man islets convert T into DHT and E2 via the intracrine activities of SRD5A1 and aromatase.
4                                          The intracrine activity of steroid metabolizing enzymes is i
5 he hypothesis that melatonin acts both as an intracrine and paracrine circadian signal of darkness, a
6 an also be produced within tissues to act in intracrine and paracrine fashions.
7                                              Intracrine androgen production and AR amplification, amo
8        Abiraterone acetate potently disrupts intracrine androgen receptor signalling pathways implica
9 ated with enzalutamide resistance; targeting intracrine androgens and AKR1C3 will overcome enzalutami
10 the current study highlights NPC2 as a novel intracrine/autocrine factor that controls adipocyte diff
11 y coexpression of DP1, suggesting a possible intracrine/autocrine signaling mechanism.
12  D can act locally at cellular level through intracrine/autocrine/paracrine feedforward and feedback
13                                              Intracrine biosynthesis of endometrial androgens during
14 rgeting complete suppression of systemic and intracrine contributions to the prostatic androgen micro
15 beta-adrenergic stimulation, arguing against intracrine control of respiration by NO within cardiac m
16             T is a prohormone that undergoes intracrine conversion in target tissues to the potent an
17 inct function of VEGF in mediating autocrine/intracrine CRC cell survival.
18                      Endothelin-1 acts in an intracrine fashion on endolysosomal ET(B) to induce nitr
19 coexist, allowing NO to work in an autocrine/intracrine fashion.
20  whether these can control respiration in an intracrine fashion.
21 slation and influence cellular events in an "intracrine" fashion.
22 ed by endothelial NO in a paracrine, but not intracrine, fashion.
23 essenger in both the autocrine/paracrine and intracrine FGF-2 pathways.
24                                              Intracrine GH acts in pituitary cells as an apoptosis sw
25 11beta-HSD1) amplifies local intracellular ("intracrine") glucocorticoid action; in the brain it is h
26         These findings reveal an unexpected 'intracrine' GPCR signaling modality involved in the loca
27 by VEGF regulates differentiation through an intracrine mechanism that is distinct from the role of s
28 the efficacy of using this drug delivery and intracrine mechanism to control the fate of human MSCs a
29                      This study discloses an intracrine mechanism whereby TRAIL blocks DR5 signaling
30  of mesenchymal stem cells (MSCs) through an intracrine mechanism, suggesting a new strategy to promo
31 and independent, act through auto-, para- or intracrine mechanisms and can be modified by hormonal si
32 vern inflammatory and immune responses as an intracrine mediator of eosinophil cytokine secretion.
33  leukotrieneC4 acts through hitherto unknown intracrine mode to elicit store-independent Ca(2+) signa
34 ted in exogenous (paracrine), autocrine, and intracrine modes.
35                      Thus, myocyte autocrine/intracrine NOS3 regulation in vivo can underlie key role
36 ght to establish if there are differences in intracrine, paracrine, and endocrine regulation of sex s
37 8 production in prostate cancer cells via an intracrine pathway independent of its classical nuclear
38  are nuclear and exert activities through an intracrine, perhaps nuclear, pathway.
39 decreased decidualization suggesting that an intracrine prostanoid pathway consisting of Cox-2, prost
40                        Stanniocalcin-1 is an intracrine protein; it binds to the cell surface, is int
41 tory forms of PTHrP, the role of PTHrP as an intracrine regulator of cell growth and cell death; (b)
42          MAP3K1 is therefore the nexus of an intracrine regulatory loop connecting the TGF-alpha/EGFR
43 1beta-HSD1 provides lymphocytes with a novel intracrine regulatory mechanism that could influence suc
44  signaling has been extensively studied, its intracrine role has been largely attributed to interacti
45                                   Peripheral intracrine sex steroid synthesis from adrenal precursors
46 d whether cysteinyl leukotrienes (cysLT) are intracrine signal transducers that regulate human eosino
47 fected with HHV-8 in an autocrine manner via intracrine signaling and that these activities may contr
48 investigate the role of these regions in the intracrine signaling of HMW FGF-2, we produced stable tr
49 brane-anchoring domain converts autocrine to intracrine signaling.
50                  In addition, intracellular (intracrine) sites of angiotensin action have been report
51 gical effects from the interior of the cell (intracrine), some of which are not inhibited by Ang rece
52                             We conclude that intracrine steroidogenesis may permit tumors to circumve
53 l require novel agents capable of inhibiting intracrine steroidogenic pathways within the prostate tu
54 cate into the nucleus, thereby serving as an intracrine stimulator of smooth muscle proliferation.
55  these studies show how VEGF functions as an intracrine survival factor in colorectal cancer cells, d
56 steroids, AR overexpression, increased local intracrine synthesis of androgens, and upregulation of t
57 teroid sulfatase (STS) inhibitors confirming intracrine synthesis to estrogen.
58  pulmonary artery smooth muscle cells via an intracrine TGF-beta1 pathway in pulmonary hypertension.
59 ibitor (compound 15) and successful targeted intracrine therapy in a mouse bone fracture model.
60 17beta-HSD2 inhibition thus enables targeted intracrine therapy.
61   In this study, we investigated the role of intracrine VEGF signaling in colorectal cancer cell surv
62 suggest that stromal-dependent paracrine and intracrine VEGF-A/VEGFR-1 signaling contributes to human
63 clear whether they control respiration in an intracrine way.