ライフサイエンスコーパス: intraepithelial

1 tion of children with STRA exhibit increased intraepithelial airway neutrophilia that correlated with

2 Intraepithelial and lamina propria CD8 Trm cells showed

3 In conclusion, our findings demonstrate that intraepithelial and lamina propria CD8(+) T cells exhibi

4 3 mutation in Pax8 + FTE caused Serous Tubal Intraepithelial Carcinoma (STIC), which metastasized rap

5 nt precursor lesions, including serous tubal intraepithelial carcinoma (STIC), with genetic heterogen

6 n tube, which first develops as serous tubal intraepithelial carcinoma (STIC).

7 one of seven predefined disease categories: intraepithelial carcinoma including actinic keratoses an

8 fallopian tube lesions, called serous tubal intraepithelial carcinoma.

9 opian tube epithelium (FTE) and serous tubal intraepithelial carcinomas (STIC) as the tissue of origi

10 p53 signatures to latter-stage, serous tubal intraepithelial carcinomas (STICs) is characterized by c

11 n tube lesions (p53 signatures, serous tubal intraepithelial carcinomas (STICs), and fallopian tube c

12 whereas many type II carcinomas develop from intraepithelial carcinomas in the fallopian tube and, as

13 Measuring the intraepithelial CD3(+) T-lymphocyte and lamina propria C

14 ted primarily in the lamina propria, whereas intraepithelial CD4(+) T cells (CD4(IELs)), which also e

15 r with a tryptophan-rich diet, can reprogram intraepithelial CD4(+) T cells into immunoregulatory T c

16 To maximize both systemic and genital intraepithelial CD8(+) T cells against vaccine Ags, we a

17 alphaEbeta7) integrin induction in activated intraepithelial CD8(+) T lymphocytes.

18 We stimulated primary intestinal intraepithelial CD8(+) T-cell lines, or CD8(+) T cells d

19 sustaining junctional tension and inhibiting intraepithelial cell movement.

20 hology confirmed malignant melanoma, with no intraepithelial component or associated melanosis.

21 Intraepithelial cytotoxic T cells from relatives of pati

22 We analyzed epithelial cells and intraepithelial cytotoxic T cells in family members of p

23 review will examine the mechanisms by which intraepithelial cytotoxic T cells mediate tissue destruc

24 Activation of intraepithelial cytotoxic T cells with IL15 or IL21 indu

25 ese cytokines selectively and its effects on intraepithelial cytotoxic T cells.

26 and IL21 cooperatively activated intestinal intraepithelial cytotoxic T cells.

27 n in sensory nerve density and the number of intraepithelial DCs in unwounded (UW) corneas.

28 Intraepithelial dysplasia of the oral mucosa typically o

29 characterized by esophageal dysfunction and intraepithelial eosinophil accumulation.

30 histologic features of EoE (peak esophageal intraepithelial eosinophil count and EoE histologic scor

31 ek 12, dupilumab reduced the peak esophageal intraepithelial eosinophil count by a mean 86.8 eosinoph

32 ma-producing lineages such as Th1, ILC1, and intraepithelial gammadelta T cells.

33 Whereas most research on intraepithelial gammadeltaT cells focuses on the skin an

34 oost induced concomitant strong systemic and intraepithelial genital-resident CD8(+) T cell responses

35 nd (SG) ILCs as well as liver and intestinal intraepithelial ILC1 have markers that denote tissue res

36 ted with histologic anal high-grade squamous intraepithelial lesion (A-HSIL) as the dependent variabl

37 r a combined endpoint of high-grade squamous intraepithelial lesion (HSIL) and anal intraepithelial n

38 oses were low-grade conjunctival melanocytic intraepithelial lesion (n = 18, 38%) and high-grade conj

39 outcomes: high-risk HPV prevalence; squamous intraepithelial lesion (SIL) or cervical intraepithelial

40 ed in an upgrade of conjunctival melanocytic intraepithelial lesion from low-grade to high-grade in 2

41 termined significance and low-grade squamous intraepithelial lesion) and CIN1+ was also significant.

42 cells, cannot exclude a high-grade squamous intraepithelial lesion, low-grade squamous intraepitheli

43 38%) and high-grade conjunctival melanocytic intraepithelial lesion/melanoma in situ (n = 29, 62%).

44 rs most predictive of high-grade melanocytic intraepithelial lesion/melanoma in situ were involvement

45 Anal squamous intraepithelial lesions (ASIL) or anal intraepithelial n

46 a higher burden of anal high-grade squamous intraepithelial lesions (HSIL) and anal cancer (AC) comp

47 t high risk for cervical high-grade squamous intraepithelial lesions (HSIL) and cervical cancer.

48 al HPV16 infection, anal high-grade squamous intraepithelial lesions (HSIL) and, hence, anal cancer.

49 gical predictors of anal high-grade squamous intraepithelial lesions (HSIL) in human immunodeficiency

50 in low-grade (LSIL) and high-grade squamous intraepithelial lesions (HSIL), and the AIN classificati

51 Anal high-grade squamous intraepithelial lesions (HSILs) ablation may reduce the

52 low-grade and 1282 with high-grade squamous intraepithelial lesions (HSILs) diagnosed cytologically;

53 Anal high-grade squamous intraepithelial lesions (HSILs) precede anal cancer, and

54 rs and/or progression to high-grade squamous intraepithelial lesions (ie, cervical intraepithelial ne

55 significance (ASC-US) or low-grade squamous intraepithelial lesions (LSIL) who were triaged with tes

56 significance (ASC-US) or low-grade squamous intraepithelial lesions (LSIL) who were triaged with tes

57 ural history of the precursor, anal squamous intraepithelial lesions (SIL), are limited.

58 Screening methods for anal squamous intraepithelial lesions (SILs) are suboptimal.

59 e precursor to this carcinoma, anal squamous intraepithelial lesions (SILs).

60 ad a higher frequency of advanced pancreatic intraepithelial lesions and more foci of invasive cancer

61 ication systems for conjunctival melanocytic intraepithelial lesions and suggests that the simplified

62 rs from patients with specimens negative for intraepithelial lesions or malignancy (NILM), and low-gr

63 current high-grade CIN2+/high-grade squamous intraepithelial lesions post-treatment.

64 pooled prevalence estimate of anal squamous intraepithelial lesions was 22.4% (95% CI, 17.3%-28.5%;

65 ication systems for conjunctival melanocytic intraepithelial lesions with the new World Health Organi

66 women with ICC, high- and low-grade squamous intraepithelial lesions, as well as, HPV-positive and he

67 increased through ASCUS, low-grade squamous intraepithelial lesions, CIN1, and CIN2 (18%-25%), up to

68 s intraepithelial lesion, low-grade squamous intraepithelial lesions, or high-grade squamous intraepi

69 d SOX10 facilitate assessment of melanocytic intraepithelial lesions, the current immunohistochemical

70 n classification of conjunctival melanocytic intraepithelial lesions.

71 raepithelial lesions, or high-grade squamous intraepithelial lesions.

72 r all patients with conjunctival melanocytic intraepithelial lesions.

73 I, 2.5%-8.5%; I(2) = 0%) high-grade squamous intraepithelial lesions.

74 -grade (LSIL) and high-grade (HSIL) squamous intraepithelial lesions.

75 mune absorbent spot, gut-homing CD8 T cells, intraepithelial leukocyte counts, and HLA-DQ2-restricted

76 ontrol mice and did not alter recruitment of intraepithelial leukocytes to esophageal tissues of IKKb

77 leukin-2, symptoms, video capsule endoscopy, intraepithelial leukocytes, and tissue multiplex immunof

78 ultured IECs resulted in dramatic defects in intraepithelial localization and replication as well as

79 ables were addressed in the small intestine: intraepithelial lymphocyte (IEL) and lamina propria lymp

80 is study, we investigate how obesity impacts intraepithelial lymphocyte (IEL) persistence and functio

81 st selection of TCRalphabeta(+)CD8alphaalpha intraepithelial lymphocyte (IEL) progenitors (IELps), ev

82 f villous atrophy were numbers of gammadelta intraepithelial lymphocyte cells followed by age and hom

83 0.66); and the difference in change in total intraepithelial lymphocyte count was -12.73% (95% CI -77

84 umed oats, 0.24; 95% CI, 0.01-4.8; P = .35), intraepithelial lymphocyte counts (standardized mean dif

85 (villous height-to-crypt depth ratio; VHCD); intraepithelial lymphocyte counts; Marsh score; and pati

86 ased intraepithelial lymphocytes, markers of intraepithelial lymphocyte cytotoxicity, gliadin-specifi

87 Effects on intraepithelial lymphocyte density and symptoms suggest

88 Secondary endpoints were CD3-positive intraepithelial lymphocyte density; clinical symptoms me

89 C(lo) supports TCRalphabeta(+) CD8alphaalpha intraepithelial lymphocyte development; meanwhile, mTEC(

90 he relative change from baseline in aberrant intraepithelial lymphocyte percentage was -4.85% (90% CI

91 in terms of the primary endpoint of aberrant intraepithelial lymphocyte reduction from baseline.

92 eta(+)CD4(-)CD8alpha(+)CD8beta(-) intestinal intraepithelial lymphocytes (CD8alphaalpha IELs) are an

93 tains CD4(+)CD8alphaalpha(+) double-positive intraepithelial lymphocytes (DP IELs), which originate f

94 ists of both resident populations-gammadelta intraepithelial lymphocytes (gammadelta IELs)-and transi

95 In this context, intestinal intraepithelial lymphocytes (IEL) compose a large, highl

96 Intestinal intraepithelial lymphocytes (IEL) comprise a diverse pop

97 opment of signature, murine TCRgammadelta(+) intraepithelial lymphocytes (IEL) in gut and skin depend

98 ion of T cell receptor gammadelta-expressing intraepithelial lymphocytes (IEL), but these changes wer

99 The number of intraepithelial lymphocytes (IELs) and immune phenotypes

100 Duodenal mucosal intraepithelial lymphocytes (IELs) and lamina propria CD

101 Intestinal intraepithelial lymphocytes (IELs) are a large and diver

102 CD8alphaalpha intraepithelial lymphocytes (IELs) are abundant T cells

103 Intestinal intraepithelial lymphocytes (IELs) are located at the cr

104 e of an enlarged clonal population of innate intraepithelial lymphocytes (IELs) lacking classical B-,

105 lial cells (ECs) is a population of resident intraepithelial lymphocytes (IELs) that provide host-pro

106 estine tissues were collected and intestinal intraepithelial lymphocytes (IELs) were measured; we als

107 of naturally occurring Vgamma4(+)/Vdelta1(+) intraepithelial lymphocytes (IELs) with innate cytolytic

108 The gut epithelium is populated by intraepithelial lymphocytes (IELs), a heterogeneous T ce

109 such as TCRalphabeta((+))CD8alphaalpha((+)) intraepithelial lymphocytes (IELs), require full-agonist

110 o recycling into intestinal CD4(-)CD8beta(-) intraepithelial lymphocytes (iIELs).

111 les (one in the AMG 714 group), and atypical intraepithelial lymphocytes (three in the AMG 714 group

112 al tissues and cells, including increases in intraepithelial lymphocytes and fluid extravasation thro

113 while cell numbers in the lamina propria and intraepithelial lymphocytes are unaffected.

114 The change in the proportion of aberrant intraepithelial lymphocytes from baseline to week 12 wit

115 but not in the maintenance of CD8alphaalpha intraepithelial lymphocytes in the intestine.

116 The density of CD3-positive intraepithelial lymphocytes increased in all groups, wit

117 Although an increased number of intestinal intraepithelial lymphocytes is observed at the inception

118 CD8alphaalpha TCRalphabeta(+) intestinal intraepithelial lymphocytes play a critical role in prom

119 of intestinal alphabeta(+) and gammadelta(+) intraepithelial lymphocytes purified from germ-free mice

120 In the epithelium, interleukin-15 activates intraepithelial lymphocytes that promote destruction of

121 response and participate in the licensing of intraepithelial lymphocytes to kill intestinal epithelia

122 from baseline to week 12 with respect to all intraepithelial lymphocytes was the primary endpoint and

123 Numbers of intraepithelial lymphocytes were significantly higher in

124 n the AMG 714 and placebo groups in aberrant intraepithelial lymphocytes with respect to epithelial c

125 ondary endpoints were the change in aberrant intraepithelial lymphocytes with respect to intestinal e

126 , CD8alphaalphaTCRalphabeta small intestinal intraepithelial lymphocytes, and innate memory phenotype

127 , CD8alphaalphaTCRalphabeta small intestinal intraepithelial lymphocytes, and innate memory phenotype

128 ce within the intestine through retention of intraepithelial lymphocytes, functional redistribution o

129 se were included in the analyses of aberrant intraepithelial lymphocytes, including the primary analy

130 Germ-free mice developed increased intraepithelial lymphocytes, markers of intraepithelial

131 villous height:crypt depth ratio, numbers of intraepithelial lymphocytes, or serologic markers of cel

132 Secondary end points included numbers of intraepithelial lymphocytes, serology test results (for

133 d Mucida discuss development and function of intraepithelial lymphocytes, which are found within the

134 Is, biopsies showed significant increases in intraepithelial lymphocytes, which were predominantly T

135 is spatially matched by Nkrp1g on subsets of intraepithelial lymphocytes.

136 imilar to that observed for mouse regulatory intraepithelial lymphocytes.

137 Intraepithelial macrophage projections, efficient phagoc

138 IL-9(+) ILC2 population, and an increase in intraepithelial mast cell numbers in the lung.

139 it does not distinguish between conjunctival intraepithelial melanin overproduction ("hyperpigmentati

140 Intraepithelial melanocytic proliferation without atypia

141 It is recommended that "intraepithelial melanocytic proliferation" be adopted fo

142 nin overproduction ("hyperpigmentation") and intraepithelial melanocytic proliferation.

143 inction between the low-grade and high-grade intraepithelial melanocytic proliferations and need to b

144 amous intraepithelial lesions (ASIL) or anal intraepithelial neoplasia (AIN) are precancerous lesions

145 -related factors on anal HPV infection, anal intraepithelial neoplasia (AIN), and anal cancer among p

146 High-grade anal intraepithelial neoplasia (AIN2/3; HGAIN) is highly prev

147 t the long-term yield of high-grade cervical intraepithelial neoplasia (CIN) and the influence on bio

148 (LEEP) for histologically confirmed cervical intraepithelial neoplasia (CIN) grade 2 or higher regard

149 We analyzed data on cervical intraepithelial neoplasia (CIN) grades 2-3 and adenocarc

150 istory and histologically confirmed cervical intraepithelial neoplasia (CIN) in 2.5 years after the b

151 ous intraepithelial lesion (SIL) or cervical intraepithelial neoplasia (CIN) prevalence, incidence, p

152 To determine the population-based cervical intraepithelial neoplasia (CIN) trends when adjusting fo

153 Comparison of conjunctival intraepithelial neoplasia (CIN) vs SCC revealed SCC with

154 rognostic test to ascertain whether cervical intraepithelial neoplasia (CIN) will regress or progress

155 hy, human papilloma virus (HPV) +/- cervical intraepithelial neoplasia (CIN), or cervical cancer.

156 papillomavirus (HPV) infection, and cervical intraepithelial neoplasia (CIN); however, causal inferen

157 ated STAT3 increased from low-grade cervical intraepithelial neoplasia (CIN1) to precancerous CIN3 le

158 asma viral load (PVL) on high-grade cervical intraepithelial neoplasia (CIN2+) detection at follow-up

159 HC2 for the detection of high-grade cervical intraepithelial neoplasia (CIN2+) in a total of 8,610 ce

160 Overall, 28 high-grade cervical intraepithelial neoplasia (CIN3) cases were detected.

161 sts for hrHPV and HPV 16/18 to find cervical intraepithelial neoplasia (grade >/=2 [CIN2+] or grade >

162 sts for hrHPV and HPV 16/18 to find cervical intraepithelial neoplasia (grade >/=2 [CIN2+] or grade >

163 ble knockouts presented high-grade prostatic intraepithelial neoplasia (HG-PIN) and hyperproliferatio

164 omavirus (HPV) genotypes-and high-grade anal intraepithelial neoplasia (HGAIN) in men who have sex wi

165 be differentiated from high-grade prostatic intraepithelial neoplasia (HGPIN), a pre-malignant intra

166 uman prostate cancer and high-grade prostate intraepithelial neoplasia (HGPIN).

167 stem (CNS) occurs as early as the pancreatic intraepithelial neoplasia (PanIN) 2 stage.

168 velopment and is induced in mouse pancreatic intraepithelial neoplasia (PanIN) and pancreatic ductal

169 ce of oncogenic KRAS, accelerates pancreatic intraepithelial neoplasia (PanIN) formation and the deve

170 ates acinar-to-ductal metaplasia, pancreatic intraepithelial neoplasia (PanIN) formation, and PanIN p

171 he earliest stages of preinvasive pancreatic intraepithelial neoplasia (PanIN) in the KrasLSL-G12D/+

172 hages contribute to fibrogenesis, pancreatic intraepithelial neoplasia (PanIN) lesion growth, and gen

173 progressively develop high-grade pancreatic intraepithelial neoplasia (PanIN) lesions and neoplasia

174 transition from early to advanced pancreatic intraepithelial neoplasia (PanIN) lesions, we assessed w

175 to-ductal metaplasia and in early pancreatic intraepithelial neoplasia (PanIN) lesions.

176 anc-28 cells and samples of human pancreatic intraepithelial neoplasia (PanIN), along with several bi

177 ed and analyzed for inflammation, pancreatic intraepithelial neoplasia (PanIN), and PDAC.

178 ), accelerated the progression of pancreatic intraepithelial neoplasia (PanIN), and resulted in the a

179 n is expressed in human and mouse pancreatic intraepithelial neoplasia (PanIN), suggesting that N-cad

180 M proteins in normal pancreas and pancreatic intraepithelial neoplasia (PanIN)- and PDAC-bearing panc

181 , thus resisting the formation of pancreatic intraepithelial neoplasia (PanIN)-derived PDA.

182 asia (ADM) and its progression to pancreatic intraepithelial neoplasia (PanIN).

183 cancer and initiate precancerous pancreatic intraepithelial neoplasia (PanINs) when induced in mouse

184 iation and expansion of low-grade pancreatic intraepithelial neoplasia (PanINs), likely through diffe

185 titute hallmark features of human pancreatic intraepithelial neoplasia (PanINs), the precursor to pan

186 sufficient to induce formation of pancreatic intraepithelial neoplasia (PanINs)-a precursor of PDAC.

187 tubular complexes (TC) and early pancreatic intraepithelial neoplasia (PanINs).

188 s in wild-type mice rarely induced prostatic intraepithelial neoplasia (PIN) in dorsal prostates (one

189 Further, prostatic intraepithelial neoplasia (PIN) progressed to carcinoma

190 sed the prevalence and severity of prostatic intraepithelial neoplasia (PIN), a premalignant lesion.

191 controls, and eventually developed prostatic intraepithelial neoplasia (PIN).

192 n paraffin-embedded VSCC and adjacent vulvar intraepithelial neoplasia (VIN) and VLS specimens, in ca

193 n of oncogenic KRAS, premalignant pancreatic intraepithelial neoplasia 1 (PanIN1) lesions rarely beco

194 ting premalignant cervical lesions (cervical intraepithelial neoplasia 2+ [CIN2+]) is an effective wa

195 ly increased with disease severity (cervical intraepithelial neoplasia [CIN] 3, 17.9% [+/-7.2] vs CIN

196 enign prostatic hyperplasia [BPH], prostatic intraepithelial neoplasia [PIN], inflammation, and atrop

197 ped an earlier onset of high-grade prostatic intraepithelial neoplasia and accelerated prostate tumor

198 (Fl/Fl)) failed to progress beyond prostatic intraepithelial neoplasia and did not harbor genomic CNA

199 es local conservative treatment for cervical intraepithelial neoplasia and early invasive cervical ca

200 diminished SC chemoattraction to pancreatic intraepithelial neoplasia and increased abdominal hypers

201 ations showed that the severity of prostatic intraepithelial neoplasia and inflammation development g

202 low but increases significantly in cervical intraepithelial neoplasia and invasive squamous cervical

203 n littermates developed high-grade prostatic intraepithelial neoplasia and prostate cancer.

204 for both pre- and postmenopausal women with intraepithelial neoplasia are discussed in the Clinical

205 1 induced histological features of prostatic intraepithelial neoplasia at 7 months of age; these feat

206 ce exhibited metaplasia-associated prostatic intraepithelial neoplasia at a low frequency.

207 fective in preventing recurrence from breast intraepithelial neoplasia but have a lower toxicity than

208 Here, we show that pancreatic intraepithelial neoplasia driven by oncogenic mutant Kra

209 diagnosed cytologically; 1198 with cervical intraepithelial neoplasia grade 1 (CIN1), 456 with CIN2,

210 nst 6-month persistent infection or cervical intraepithelial neoplasia grade 1 or greater (CIN1+) ass

211 ic diagnosis of controls (less than cervical intraepithelial neoplasia grade 2 [<CIN2]) or cases (cer

212 nce of high-grade cervical disease (cervical intraepithelial neoplasia grade 2 or 3, adenocarcinoma i

213 Sensitivity of detecting cervical intraepithelial neoplasia grade 2 or greater in HIV-nega

214 types) were informative to predict cervical intraepithelial neoplasia grade 2 or greater.

215 the Xpert HPV for the detection of cervical intraepithelial neoplasia grade 2 or higher (CIN2+) and

216 aginal samples for the detection of cervical intraepithelial neoplasia grade 2 or higher (CIN2+).

217 eoplasia grade 2 [<CIN2]) or cases (cervical intraepithelial neoplasia grade 2 or higher [CIN2+]) for

218 des 2/3 and adenocarcinoma in situ (cervical intraepithelial neoplasia grade 2 or higher [CIN2+]) in

219 amous intraepithelial lesion (HSIL) and anal intraepithelial neoplasia grade 2 or more severe diagnos

220 of doses administered, diagnoses of cervical intraepithelial neoplasia grade 2 or worse (CIN2+) or gr

221 for preventing HPV 16/18-associated cervical intraepithelial neoplasia grade 2 or worse (CIN2+).

222 ons, anogenital wart diagnoses, and cervical intraepithelial neoplasia grade 2+ (CIN2+) to summarise

223 lastic lesions and invasive cancer (cervical intraepithelial neoplasia grade 2+ [CIN2+]) compared to

224 uamous intraepithelial lesions (ie, cervical intraepithelial neoplasia grade 2/3 [CIN 2/3]) and (2) i

225 vulvar cancer), and vaginal disease (vaginal intraepithelial neoplasia grade 2/3, vaginal cancer) rel

226 cervical carcinoma), vulvar disease (vulvar intraepithelial neoplasia grade 2/3, vulvar cancer), and

227 alignancies in women diagnosed with cervical intraepithelial neoplasia grade 3 (CIN3).

228 topathologically confirmed CIN2+ or cervical intraepithelial neoplasia grade 3 or worse associated wi

229 ancer, 6.68 (95% CI, 3.64 to 12.25) for anal intraepithelial neoplasia grade 3, 4.97 (95% CI, 3.26 to

230 er, 13.66 (93% CI, 9.69 to 19.25) for vulvar intraepithelial neoplasia grade 3, 86.08 (95% CI, 11.98

231 , 25.65 (95% CI, 10.50 to 62.69) for vaginal intraepithelial neoplasia grade 3, and 5.51 (95% CI, 1.2

232 We describe changes in rates of cervical intraepithelial neoplasia grades 2, 3 and adenocarcinoma

233 We analyzed data on cervical intraepithelial neoplasia grades 2-3 and adenocarcinoma

234 implemented mandatory reporting of cervical intraepithelial neoplasia grades 2/3 and adenocarcinoma

235 D2A resulted in the development of prostatic intraepithelial neoplasia in mice, demonstrating that JM

236 cally attenuates the formation of pancreatic intraepithelial neoplasia induced by mutant Kras(G12D),

237 Prostatic intraepithelial neoplasia is a precursor to prostate can

238 ce and the replicative activity of prostatic intraepithelial neoplasia lesions in the dorsal prostate

239 l metaplasia (ADM)-a precursor of pancreatic intraepithelial neoplasia lesions that can progress to P

240 f diagnoses of anogenital warts and cervical intraepithelial neoplasia of grade 2 or 3 and cases of c

241 f diagnoses of anogenital warts and cervical intraepithelial neoplasia of grade 2 or 3 and cases of c

242 incident persistent qHPV infection, cervical intraepithelial neoplasia of grade 2 or higher [CIN2+],

243 of residual or recurrent high-grade cervical intraepithelial neoplasia of grade two or worse (CIN2+)

244 of the mucin family during early pancreatic intraepithelial neoplasia stage I (PanIN-I) of pancreati

245 d cancer is not suspected, usual-type vulvar intraepithelial neoplasia treatment, including medical a

246 syndrome, clonal hematopoiesis, and cervical intraepithelial neoplasia which also serve as models for

247 r 3 years can halve the recurrence of breast intraepithelial neoplasia with a limited toxicity, which

248 mation of precancerous lesions (endometrioid intraepithelial neoplasia) and well-differentiated endom

249 rly neoplastic lesions (high-grade prostatic intraepithelial neoplasia) with striking nuclear atypia

250 6% for PAM, 67% for conjunctival melanocytic intraepithelial neoplasia, and 81% for WHO classificatio

251 eads to the formation of kidney cysts, renal intraepithelial neoplasia, and invasive papillary renal

252 ation systems: PAM, conjunctival melanocytic intraepithelial neoplasia, and the WHO 4th edition class

253 PRKD1(KO)-KC mice developed more pancreatic intraepithelial neoplasia, at a faster rate, than KC mic

254 ally accelerated the progression of prostate intraepithelial neoplasia, by promoting cell proliferati

255 normal prostate glands, high-grade prostatic intraepithelial neoplasia, invasive adenocarcinoma, or p

256 d densely methylated in high-grade prostatic intraepithelial neoplasia, primary prostate carcinoma, a

257 human pancreatic cancer cells and pancreatic intraepithelial neoplasia, the early lesion of pancreati

258 ntial reduction of ADM as well as pancreatic intraepithelial neoplasia-1 (PanIN-1), PanIN-2, and PanI

259 cifically overexpress ETV1 develop prostatic intraepithelial neoplasia.

260 e without affecting hyperplasia or prostatic intraepithelial neoplasia.

261 n Dist-Luminal-C cells resulted in prostatic intraepithelial neoplasia.

262 and tolerable for treating usual-type vulvar intraepithelial neoplasia?

263 Cervical dysplastic lesions called cervical intraepithelial neoplasias (CINs) need be treated to pre

264 rognostic test to ascertain whether cervical intraepithelial neoplasias (CINs) regress or progress.

265 olves visualisation of high-grade pancreatic intraepithelial neoplasias (PanIN-3), generally regarded

266 olves visualization of high-grade pancreatic intraepithelial neoplasias (PanIN-3s), generally regarde

267 s the development of premalignant pancreatic intraepithelial neoplasias (PanINs) and cystic lesions i

268 cinar-to-ductal metaplasia (ADM), pancreatic intraepithelial neoplasias (PanINs) and ultimately pancr

269 rom the transgenic mice regenerated prostate intraepithelial neoplasias and prostatic adenocarcinoma

270 mucinous cystic neoplasms, while pancreatic intraepithelial neoplasias are rarely detected.

271 that TopBP1 levels are increased in cervical intraepithelial neoplasias as well as cervical carcinoma

272 was upregulated in patients with pancreatic intraepithelial neoplasias grade 3 and PDAC lesions rela

273 al activation entirely surrounded pancreatic intraepithelial neoplasias in KPC/Cdh11(+/+) mice and in

274 reater number and higher grade of pancreatic intraepithelial neoplasias than KC mice, and 1 mouse dev

275 (2 benign papillomas, 2 grade 2 conjunctival intraepithelial neoplasias, 7 in situ squamous carcinoma

276 decreased formation of high-grade pancreatic intraepithelial neoplasias, and accelerated development

277 y analyzed for formation of IPMN, pancreatic intraepithelial neoplasias, and PDAC, in addition to pro

278 o early pancreatic lesions called pancreatic intraepithelial neoplasias, which are challenging to det

279 is an essential component of the pancreatic intraepithelial neoplasias-to-PDAC route in Kras(G12D)-d

280 grade dysplasia and some enlarged pancreatic intraepithelial neoplasias.

281 pancreatic ducts, referred to as pancreatic intraepithelial neoplasias.

282 mice, but did not alter growth of pancreatic intraepithelial neoplasias.

283 yses of precursor lesions, termed pancreatic intraepithelial neoplasm (PanINs) lesions, makes two pre

284 rous pancreatic lesions, known as pancreatic intraepithelial neoplasms (PanIN), and describe a unique

285 ary mucinous neoplasms or grade 3 pancreatic intraepithelial neoplasms).

286 g increases detection of high-grade cervical intraepithelial neoplastic lesions and invasive cancer (

287 Children with STRA had increased intraepithelial neutrophils, which positively correlated

288 Intraepithelial nonproliferative melanocytic pigmentatio

289 lasms (IPMN), 2 adenocarcinomas, 1 low-grade intraepithelial pancreatic neoplasia, and 1 case of poly

290 em cells, blocks the progression of indolent intraepithelial prostatic lesions into aggressive and ra

291 e downregulation of tbpAB and hmbR, while an intraepithelial replication defect was consistent with t

292 ose an alternative mechanical model based on intraepithelial stresses generated by differential tensi

293 Intraepithelial/stromal tumor-infiltrating lymphocytes (

294 AM) is a cell adhesion molecule expressed by intraepithelial T cells and is required for their retent

295 ages, decreased abundance of CD39-expressing intraepithelial T cells, and platelet aggregation and re

296 f immune cells-integrin beta7(+) natural gut intraepithelial T lymphocytes (natural IELs)-that is dis

297 CD4(+) and CD4(+)CD8(+) alphabeta intraepithelial T lymphocytes exhibit reduced homeostati

298 The reduction in intraepithelial T lymphocytes occurs within 7 wk of high

299 um is maintained by alphabeta and gammadelta intraepithelial T lymphocytes, which migrate along the e

300 he ablated areas, which appeared to be small intraepithelial vesicles.