ライフサイエンスコーパス: intraflagellar transport

1 eins transmit force for ciliary motility and intraflagellar transport.

2 ctural precursors delivered to their tips by intraflagellar transport.

3 n-2 family member best known for its role in intraflagellar transport.

4 ugh the degradation of proteins required for intraflagellar transport.

5 otein-coupled receptors GPCRs or by blocking intraflagellar transport.

6 t they show features of defective retrograde intraflagellar transport.

7 Shh signaling regulates this balance through intraflagellar transport.

8 ilia construction or maintenance, but not in intraflagellar transport.

9 lium morphology and provides a substrate for intraflagellar transport.

10 a novel ciliary gene required for retrograde intraflagellar transport.

11 ynein-2 complex are essential for retrograde intraflagellar transport.

12 nt data support a role in cilia function and intraflagellar transport.

13 on of genes associated with ciliogenesis and intraflagellar transport.

14 eviously in a subset of mutants defective in intraflagellar transport.

15 (-/-) basal bodies, suggesting impairment of intraflagellar transport.

16 syndrome when mutated, in the triggering of intraflagellar transport.

17 sting 9+2 axonemes associated with decreased intraflagellar transport.

18 t that a length-dependent feedback regulates intraflagellar transport.

19 n three families, we identified mutations in Intraflagellar Transport 172 Homolog [IFT172 (Chlamydomo

20 Here, we identify intraflagellar transport 20 (IFT20) as a new target of t

21 Knockout of intraflagellar transport 88 (IFT88) confirmed that the c

22 Stable silencing of Intraflagellar Transport 88 (Ift88) or Kinesin Family Me

23 nsport [kinesin family member 3A (Kif3a) and intraflagellar transport 88 (Ift88)] and Cre drivers tha

24 so known as polaris or Tg737), which encodes intraflagellar transport 88 homolog, and Kif3a, which en

25 remodeling and centrosome migration, whereas intraflagellar transport 88's role seems to be restricte

26 vely, a recent finding has revealed that the intraflagellar transport 88/polaris protein, which is re

27 Down-regulation of intraflagellar transport-88, a protein essential for cil

28 INTU is essential for intraflagellar transport A complex assembly during cilio

29 ated that the TTC21B gene product IFT139, an intraflagellar transport-A component, mainly localizes a

30 Kinesin-2 motors, which are involved in intraflagellar transport and cargo transport along cytop

31 mselves, and show that crumbs genes modulate intraflagellar transport and cilia elongation.

32 esin II subunit Kif3A, which is required for intraflagellar transport and ciliogenesis.

33 KIF3A/B, a kinesin involved in intraflagellar transport and Golgi trafficking, is disti

34 Cytoplasmic dynein-2 (dynein-2) performs intraflagellar transport and is associated with human sk

35 Intraflagellar transport and kinesin-3 KLP-6 are require

36 nesin II motor complex, that is required for intraflagellar transport and the formation of cilia, was

37 Epistasis analyses indicate that DAF-6/intraflagellar transport and the OCR-2/OSM-9 TRPV channe

38 How might intraflagellar transport and the size of the trains be i

39 F3A/B, is a heterotrimeric motor involved in intraflagellar transport and vesicle motility in neurons

40 in the cytoplasm, transported into cilia by intraflagellar transport, and bound to specific sites on

41 in isotype regulates ciliary ultrastructure, intraflagellar transport, and ciliary functions of extra

42 equires an active transport process known as intraflagellar transport, and previous measurements sugg

43 s to predict the relation between length and intraflagellar transport, and then compare the predicted

44 length-dependent signal produced to regulate intraflagellar transport appropriately?

45 ptures and releases its single effector, the intraflagellar transport B holocomplex, from the large p

46 interaction (PPI) network analysis of known intraflagellar transport, BBSome, transition zone, cilia

47 entify the role of kinesin-II in anterograde intraflagellar transport by photoreceptor-specific delet

48 sive return of the kinesin motor that powers intraflagellar transport can play a key role in length r

49 affecting ciliary assembly, mutations in the intraflagellar transport complex A (IFT-A) paradoxically

50 ,5)P2)-dependent manner, ciliary delivery by intraflagellar transport complex A binding to the TULP3/

51 r characterization of specific components of Intraflagellar Transport complex A uncovered a cilia-ind

52 requiring the receptor cytoplasmic tail, the intraflagellar transport complex-B (IFT-B), and ciliary

53 which encodes a component of the anterograde intraflagellar transport complex.

54 lia and flagella, and recent work shows that intraflagellar transport complexes - or trains - fall in

55 stern blots revealed that the bulges contain intraflagellar transport complexes, a defect reported pr

56 We observe sub-complexes in exocyst and intraflagellar transport complexes, which we validate bi

57 The intraflagellar transport component polaris localized to

58 imilarly, knockdown of ift22, an anterograde intraflagellar transport component, also suppresses the

59 In mutant OSNs, cilia base-anchoring of intraflagellar transport components IFT88, the kinesin-I

60 ents are not well understood, but defects in intraflagellar transport components, including Ift27 and

61 Mutants of daf-6 or intraflagellar transport constitutively upregulate tph-1

62 Ciliary dysfunction caused by intraflagellar transport defects results in branching de

63 mbrane attachments before or coinciding with intraflagellar transport-dependent axoneme extension and

64 ioles at the plasma membrane but not for the intraflagellar transport-dependent extension of the cili

65 genes encoding cytoplasmic assembly factors, intraflagellar transport factors, docking proteins, dyne

66 n et al. describe the necessity of Ift88 and intraflagellar transport for signal reception of the son

67 cription factors, foxj1 and rfx2, and of the intraflagellar transport gene ift88 (also known as polar

68 ephros fluid output through knockdown of the intraflagellar transport gene ift88, was not associated

69 ing ciliopathies and argue that mutations in intraflagellar transport genes cause their phenotypes be

70 ecause endothelial-specific re-expression of intraflagellar transport genes in respective mutants res

71 Embryos expressing mutant intraflagellar transport genes, which are essential and

72 oducts from the flagellar tip is mediated by intraflagellar transport (IFT) , which is essential for

73 Here, we examine the role of intraflagellar transport (IFT) 20 (Ift20) during polariz

74 require the universally conserved process of intraflagellar transport (IFT) [1, 2].

75 per se of SAG1 is independent of anterograde intraflagellar transport (IFT) [13], but the rapid apica

76 arrier at the base of the organelle [3-8] by intraflagellar transport (IFT) [9-18].

77 aintenance of all cilia and flagella require intraflagellar transport (IFT) along the axoneme.

78 semble from basal bodies by a process called intraflagellar transport (IFT) and are associated with s

79 ins in primary cilia is thought to depend on intraflagellar transport (IFT) and diffusion.

80 crotubule-based organelles that assemble via intraflagellar transport (IFT) and function as signaling

81 Both intraflagellar transport (IFT) and lipidated protein int

82 GFP-tagged alpha-tubulin enters cilia as an intraflagellar transport (IFT) cargo and by diffusion.

83 Mutations in several genes affecting intraflagellar transport (IFT) cause SRPS but they do no

84 rily of HEAT repeats, may not be part of the intraflagellar transport (IFT) complex and is not requir

85 IFT80, a protein component of intraflagellar transport (IFT) complex B, is required fo

86 unction of Ift27, which encodes a subunit of intraflagellar transport (IFT) complex B.

87 The intraflagellar transport (IFT) complex is an integral co

88 Binding protein (SLB), is a component of the intraflagellar transport (IFT) complex.

89 Intraflagellar transport (IFT) complexes A and B build a

90 Two intraflagellar transport (IFT) complexes, IFT-A and IFT-

91 ization (aCGH) covering 20 genes that encode intraflagellar transport (IFT) components and 74 ciliopa

92 ization of other ciliary proteins, including intraflagellar transport (IFT) components, sensory recep

93 very similar, but not identical, to that of intraflagellar transport (IFT) components.

94 aintenance of eukaryotic cilia and flagella, intraflagellar transport (IFT) consists of the bidirecti

95 Intraflagellar transport (IFT) depends on two evolutiona

96 Anterograde intraflagellar transport (IFT) employing kinesin-2 molec

97 Across eukaryotes, intraflagellar transport (IFT) facilitates cilia biogene

98 This is the first time an intraflagellar transport (IFT) gene is implicated in the

99 netic approach in mice identified a role for intraflagellar transport (IFT) genes in Shh signal trans

100 nal (anterograde and retrograde) motor-based intraflagellar transport (IFT) governs cargo transport a

101 least BBS1, -4, -5, -7, and -8 and undergoes intraflagellar transport (IFT) in association with a sub

102 n FLA15 and FLA17 show defects in retrograde intraflagellar transport (IFT) in Chlamydomonas.

103 Loss of TCTEX1D2 impairs retrograde intraflagellar transport (IFT) in humans and the protist

104 toplasmic dynein 2, the motor for retrograde intraflagellar transport (IFT) in primary cilia.

105 Eukaryotic cilia are assembled via intraflagellar transport (IFT) in which large protein pa

106 Intraflagellar transport (IFT) is a bidirectional proces

107 Intraflagellar transport (IFT) is a motility process ope

108 Intraflagellar transport (IFT) is a process required for

109 Intraflagellar transport (IFT) is an active event in whi

110 Intraflagellar transport (IFT) is an ancient, conserved

111 Intraflagellar transport (IFT) is an evolutionarily cons

112 Intraflagellar transport (IFT) is assumed to be the pred

113 Anterograde intraflagellar transport (IFT) is essential for photorec

114 Intraflagellar transport (IFT) is essential for the elon

115 Anterograde intraflagellar transport (IFT) is mediated by kinesin mo

116 Intraflagellar transport (IFT) is not essential for PKD-

117 Retrograde intraflagellar transport (IFT) is required for assembly

118 Intraflagellar transport (IFT) is required for proper fu

119 Intraflagellar transport (IFT) is required for the assem

120 Intraflagellar transport (IFT) is the bidirectional move

121 Intraflagellar transport (IFT) is the process by which p

122 a, tba-6 regulates velocities and cargoes of intraflagellar transport (IFT) kinesin-2 motors kinesin-

123 17 and kinesin-3 KLP-6 without affecting the intraflagellar transport (IFT) kinesin-II.

124 Sensory cilia are assembled by intraflagellar transport (IFT) kinesins, which transport

125 tmentalized ciliogenesis depends on the core intraflagellar transport (IFT) machinery and the associa

126 The intraflagellar transport (IFT) machinery consists of the

127 Intraflagellar transport (IFT) machinery is required for

128 ciliary membranes at rates comparable to the intraflagellar transport (IFT) machinery located between

129 Intraflagellar transport (IFT) machinery mediates the bi

130 kinesin-2 subunit Kif3a, a component of the intraflagellar transport (IFT) machinery used to generat

131 Cilia are assembled and maintained by the intraflagellar transport (IFT) machinery, which coordina

132 et-Biedl syndrome (BBS) proteins, and on the intraflagellar transport (IFT) machinery.

133 er centrioles, and IFT88, a component of the intraflagellar transport (IFT) machinery.

134 Intraflagellar transport (IFT) motor protein localizatio

135 y assembly and maintenance as an anterograde intraflagellar transport (IFT) motor.

136 Intraflagellar transport (IFT) motors assemble and maint

137 Characterization of previously described intraflagellar transport (IFT) mouse mutants has led to

138 Intraflagellar transport (IFT) moves IFT trains carrying

139 This phenotype is much less pronounced in intraflagellar transport (IFT) mutants and reveals that

140 e during flagellar resorption, especially in intraflagellar transport (IFT) mutants, suggesting that

141 s neurons depends on the kinesin-2-dependent intraflagellar transport (IFT) of ciliary precursors ass

142 Cilia are assembled via intraflagellar transport (IFT) of ciliary precursors; ho

143 rated that kinesin-II drives the anterograde intraflagellar transport (IFT) of protein complexes alon

144 Cilia and flagella are assembled by intraflagellar transport (IFT) of protein complexes that

145 umption is that proteins responsible for the intraflagellar transport (IFT) of tubulin are present in

146 Moreover, intraflagellar transport (IFT) particle components accum

147 Intraflagellar transport (IFT) particle composition was

148 examine the role of the IFT20 subunit of the intraflagellar transport (IFT) particle in photoreceptor

149 Conserved intraflagellar transport (IFT) particle proteins and IFT

150 -3-kinesin, which cooperate to move the same intraflagellar transport (IFT) particles along microtubu

151 Intraflagellar transport (IFT) particles are multiprotei

152 Chlamydomonas reinhardtii intraflagellar transport (IFT) particles can be biochemi

153 hlamydomonas genes that encode components of intraflagellar transport (IFT) particles involved in cil

154 rate, and the rate of entry into flagella of intraflagellar transport (IFT) particles is increased.

155 Intraflagellar transport (IFT) particles of Chlamydomona

156 HYLS-1 compromises the docking and entry of intraflagellar transport (IFT) particles, ciliary gating

157 is molecular architecture, two reservoirs of intraflagellar transport (IFT) particles, correlating wi

158 y activity and interact genetically with the intraflagellar transport (IFT) pathway to play a role in

159 may traffic to the primary cilium through an intraflagellar transport (IFT) pathway.

160 Highly conserved intraflagellar transport (IFT) protein complexes direct

161 -1 product (CMG-1), a human homologue of the intraflagellar transport (IFT) protein IFT-71 in Chlamyd

162 the transport adaptor ODA16, as well as the intraflagellar transport (IFT) protein IFT46, but the mo

163 lishing the first association of a defective intraflagellar transport (IFT) protein with human diseas

164 We show that in mice mutant for a cilia intraflagellar transport (IFT) protein, IFT88/polaris, S

165 ealed moderately altered expression of known intraflagellar transport (IFT) protein-encoding loci in

166 The highly conserved intraflagellar transport (IFT) proteins are essential fo

167 Intraflagellar transport (IFT) proteins are essential fo

168 Intraflagellar transport (IFT) proteins are essential fo

169 gulators of animal development and depend on intraflagellar transport (IFT) proteins for their format

170 The intraflagellar transport (IFT) proteins Ift172/Wimple an

171 d and maintained by evolutionarily conserved intraflagellar transport (IFT) proteins that are involve

172 Intraflagellar transport (IFT) proteins were first ident

173 ODA16 localization resembles that seen for intraflagellar transport (IFT) proteins, and flagellar a

174 Disruption of intraflagellar transport (IFT) results in loss of flagel

175 are unusual in that they do not require the intraflagellar transport (IFT) system for assembly of th

176 The intraflagellar transport (IFT) system is required for bu

177 Ciliogenesis is accomplished by the intraflagellar transport (IFT) system, a set of proteins

178 Cilia use microtubule-based intraflagellar transport (IFT) to organize intercellular

179 he kinesin-2-driven anterograde transport of intraflagellar transport (IFT) trains has long been susp

180 Dynein-2 assembles with polymeric intraflagellar transport (IFT) trains to form a transpor

181 Intraflagellar transport (IFT) underpins many of the imp

182 Intraflagellar transport (IFT) uses kinesin II to carry

183 s are required to establish sensory cilia by intraflagellar transport (IFT) where KIF3 and KIF17 coop

184 hog (Hh) signaling in vertebrates depends on intraflagellar transport (IFT) within primary cilia.

185 ntenance of primary cilia are facilitated by intraflagellar transport (IFT), a bidirectional protein

186 e assembled and maintained by the process of intraflagellar transport (IFT), a highly conserved mecha

187 Assembly of cilia and flagella requires intraflagellar transport (IFT), a highly regulated kines

188 Ciliary assembly requires intraflagellar transport (IFT), a motile system that del

189 axonemal subunits at the tip are mediated by intraflagellar transport (IFT), a motility process essen

190 Sensory cilia and intraflagellar transport (IFT), a pathway essential for

191 m Caenorhabditis elegans that is involved in intraflagellar transport (IFT), a process essential for

192 of proteins within the cilia is governed by intraflagellar transport (IFT), a process that facilitat

193 Cilia assembly is mediated by intraflagellar transport (IFT), and cilia defects disrup

194 Cilia formation requires intraflagellar transport (IFT), and mutations disrupting

195 y opsin to test whether the highly conserved intraflagellar transport (IFT), as driven by heterotrime

196 alcium levels and requires kinesin-II-driven intraflagellar transport (IFT), as well as BBS- and RAB8

197 oth the frequency and velocity of retrograde intraflagellar transport (IFT), but it does not eliminat

198 ined by kinesin-2 motors in a process termed intraflagellar transport (IFT), but they exhibit great v

199 rs that act jointly to carry out anterograde intraflagellar transport (IFT), ferrying cargo along mic

200 Kif3a, a component of intraflagellar transport (IFT), is important in cilia ma

201 afficking of components within cilia, called intraflagellar transport (IFT), is powered by kinesin-2

202 ve been classified as putatively involved in intraflagellar transport (IFT), the bidirectional moveme

203 Intraflagellar transport (IFT), the bidirectional moveme

204 onstruction of cilia and flagella depends on intraflagellar transport (IFT), the bidirectional moveme

205 ance of eukaryotic flagella are regulated by intraflagellar transport (IFT), the bidirectional traffi

206 activator for an anterograde motor OSM-3 of intraflagellar transport (IFT), the ciliogenesis-require

207 Intraflagellar transport (IFT), the motor-dependent move

208 g flagellar shortening and in the absence of intraflagellar transport (IFT), the predominant protein

209 During intraflagellar transport (IFT), the regulation of motor

210 IFT88, essential for anterograde intraflagellar transport (IFT), was significantly reduce

211 ney disease 2 (PKD2) and its relationship to intraflagellar transport (IFT), we cloned the gene encod

212 built and maintained by continuous cycles of intraflagellar transport (IFT), where ciliary proteins a

213 Primary cilia are built and maintained by intraflagellar transport (IFT), whereby the two IFT comp

214 An essential component of ciliogenesis is intraflagellar transport (IFT), which is involved in IFT

215 Intraflagellar transport (IFT), which is the bidirection

216 n this category are known to be required for intraflagellar transport (IFT), which is the bidirection

217 he assembly of primary cilia is dependent on intraflagellar transport (IFT), which mediates the bidir

218 system consists of three subcomplexes [i.e., intraflagellar transport (IFT)-A, IFT-B, and the BBSome]

219 ematical modeling of conserved components of intraflagellar transport (IFT)-mediated assembly and kin

220 large protein complexes in a process termed intraflagellar transport (IFT).

221 ins besides a possible role for motor-driven Intraflagellar Transport (IFT).

222 luding BBS4, that is cycled through cilia by intraflagellar transport (IFT).

223 Kif3a, a subunit of Kinesin II essential for intraflagellar transport (IFT).

224 d to require both anterograde and retrograde intraflagellar transport (IFT).

225 ide repeat-containing protein related to the intraflagellar transport (IFT).

226 ssembled and maintained by the bidirectional intraflagellar transport (IFT).

227 cause B tubule defects that further disrupt intraflagellar transport (IFT).

228 ctural cores assembling from basal bodies by intraflagellar transport (IFT).

229 eostasis and are assembled and maintained by intraflagellar transport (IFT).

230 ed through a highly conserved process called intraflagellar transport (IFT).

231 cilia and flagella depends on bidirectional intraflagellar transport (IFT).

232 equires an active transport process known as intraflagellar transport (IFT).

233 Cilia are assembled via intraflagellar transport (IFT).

234 TTC26 (intraflagellar transport [IFT] 56/DYF13) is an atypical

235 siRNA inhibition of anterograde intraflagellar transport (IFT88) reduced cilia length an

236 ata suggest a tantalizing connection between intraflagellar transport in cilia and brain development.

237 Intraflagellar transport in cilia has been proposed as a

238 ns and implicate the molecular components of intraflagellar transport in degenerative disorders of th

239 ptor cells of the retina, we have focused on intraflagellar transport in photoreceptor sensory cilia.

240 Intraflagellar transport is a conserved delivery system

241 Intraflagellar transport is essential for the assembly a

242 Intraflagellar transport is involved in the assembly of

243 Anterograde intraflagellar transport is sped up in lengthened cilia,

244 Intraflagellar transport is the rapid, bidirectional mov

245 conditional alleles for genes essential for intraflagellar transport [kinesin family member 3A (Kif3

246 gellar transport (IFT) and lipidated protein intraflagellar transport (LIFT) pathways are essential f

247 e different measurements: 1) the quantity of intraflagellar transport machinery as a function of leng

248 We find that the quantity of intraflagellar transport machinery is independent of len

249 The intraflagellar transport machinery is required for the a

250 ecent identification in Chlamydomonas of the intraflagellar transport machinery that assembles cilia

251 loading onto the constitutively trafficking intraflagellar transport machinery.

252 proteins such as GPCRs and links them to the intraflagellar transport machinery.

253 Hh receptor Patched-related factor DAF-6 and intraflagellar transport modulate serotonin production i

254 vation of the Kif3a subunit of the kinesin-2 intraflagellar transport motor in mesenchymal skeletal p

255 The Chlamydomonas anterograde intraflagellar transport motor, kinesin-2, is isolated a

256 mediate chain associated with the retrograde intraflagellar transport motor.

257 required for the functional coordination of intraflagellar transport motors and their cargoes.

258 lia and that Gli3 processing is defective in intraflagellar transport mutants.

259 nance and signaling via Tulp3, essential for intraflagellar transport of ciliary signaling receptors.

260 hancement of fluorescence signal in tracking intraflagellar transport particles, or reduction of phot

261 to an opening well suited for the passage of intraflagellar transport particles.

262 ignaling and adhesion molecules, and ciliary intraflagellar transport particles.

263 ivity to PIFTC3, encoding a component of the intraflagellar transport pathway.

264 tes cilia length through an Fgf8/Fgf24-Fgfr1-intraflagellar transport pathway.

265 ssociation of RPGR-ORF15 isoform(s) with the intraflagellar transport polypeptide IFT88 as well as mi

266 wo recent studies have shown that defects in intraflagellar transport prevent assembly of sensory cil

267 to differ significantly in length indicating intraflagellar transport processes in primary cilia may

268 Unlike zebrafish intraflagellar transport protein (IFT) mutants, cyst for

269 icing variants in WDR35, encoding retrograde intraflagellar transport protein 121 (IFT121), in three

270 of open brain (sopb), a null allele of mouse Intraflagellar transport protein 122 (Ift122).

271 howed that avc1 is a hypomorphic mutation of intraflagellar transport protein 172 (Ift172), required

272 Here, we provide evidence that intraflagellar transport protein 20 (IFT20) interacts wi

273 We showed previously that the intraflagellar transport protein 20 (IFT20), a component

274 icrotubule nucleation, Golgi distribution of intraflagellar transport protein 20 homologue, and cilio

275 Effect of the variant observed in the gene Intraflagellar Transport Protein 43 (IFT43) was studied

276 We show that SDCCAG3 interacts with the intraflagellar transport protein 88 (IFT88), a crucial c

277 kinesin family member 3A) or Ift88 (encoding intraflagellar transport protein 88), genes required for

278 iption requires kinesin family member 3a and intraflagellar transport protein 88, proteins that are e

279 recent examples include the demonstration of intraflagellar transport protein and hedgehog contributi

280 e antenna-like structures are synthesized by intraflagellar transport protein complexes, IFT-B and IF

281 ions in TTC21B, which encodes the retrograde intraflagellar transport protein IFT139, cause both isol

282 gastric cilia, we conditionally deleted the intraflagellar transport protein Ift88 (Ift88(-/fl)).

283 ough mice with a hypomorphic mutation in the intraflagellar transport protein IFT88 (Ift88Tg737Rpw mi

284 formation and centriolar recruitment of the intraflagellar transport protein Ift88.

285 Elimination of the intraflagellar transport protein Kif3a leads to excessiv

286 T52, encoding a homolog of the Chlamydomonas intraflagellar transport protein, IFT52.

287 , prenylated phosphodiesterase-6 (PDE6), and intraflagellar transport protein-88 (IFT88).

288 Intraflagellar transport proteins (IFT) are required for

289 performed shRNA-mediated knockdown of seven intraflagellar transport proteins (IFTs) and conditional

290 ges were associated with increased levels of intraflagellar transport proteins and accelerated ciliog

291 This pathway also includes genes encoding intraflagellar transport proteins and cyclic nucleotide

292 rotein content, including abnormal levels of intraflagellar transport proteins and proteins associate

293 germline stem cell populations, and require intraflagellar transport proteins for their formation.

294 C2cd3 is also required for recruiting the intraflagellar transport proteins Ift88 and Ift52 to the

295 The unanticipated involvement of several intraflagellar transport proteins in the mammalian Hedge

296 ncluding removal of CP110 and recruitment of intraflagellar transport proteins.

297 complete removal of cilia by inactivation of intraflagellar transport-related proteins.

298 localization, in tight coordination with the intraflagellar transport system and vesicular traffickin

299 sport protein 20 (IFT20), a component of the intraflagellar transport system, controls polarized traf

300 the base of mature cilia and is required for intraflagellar transport trafficking.

301 ent due to the inherent length dependence of intraflagellar transport, whereas disassembly is length