ライフサイエンスコーパス: intrahepatic bile duct

1 biliary glands within extrahepatic and large intrahepatic bile ducts.

2 uction of the extrahepatic biliary tract and intrahepatic bile ducts.

3 from chronic inflammatory destruction of the intrahepatic bile ducts.

4 t culminates in fibrosis of extrahepatic and intrahepatic bile ducts.

5 e in the context of progressively developing intrahepatic bile ducts.

6 , the destruction in PBC is limited to small intrahepatic bile ducts.

7 volves formation of liver cysts derived from intrahepatic bile ducts.

8 ted by autoreactive T cells infiltrating the intrahepatic bile ducts.

9 tes and cholangiocytes, the cells lining the intrahepatic bile ducts.

10 med for disease conditions featuring loss of intrahepatic bile ducts.

11 accumulation of viscous mucoid secretions in intrahepatic bile ducts.

12 disease characterized by destruction of the intrahepatic bile ducts.

13 iver disease characterized by destruction of intrahepatic bile ducts.

14 adolinium administration = 1 x dilatation of intrahepatic bile ducts + 2 x dysmorphy + 1 x portal hyp

15 son-years of follow-up, 851 gallbladder, 588 intrahepatic bile duct, 753 extrahepatic bile duct, and

16 jority of patients (62%) were diagnosed with intrahepatic bile duct adenocarcinoma.

17 Intrahepatic bile duct anatomy is complex with many comm

18 hex(d2,3/-)) caused irregular development of intrahepatic bile ducts and an absence of Hnf1beta in ma

19 wth retardation, impaired differentiation of intrahepatic bile ducts and defects in heart, eye and ki

20 the characteristic phenotype of high-density intrahepatic bile ducts and enlarged liver in Rosa(NICD/

21 ealed that NK cells populate the vicinity of intrahepatic bile ducts and overexpress several genes in

22 ized by progressive destruction of the small intrahepatic bile ducts and portal inflammation, leading

23 mpt surgical intervention, ongoing injury of intrahepatic bile ducts and progressive cholangiopathy l

24 Cystic dysplasia of the intrahepatic bile ducts and progressive portal fibrosis

25 aracterized by neonatal jaundice, paucity of intrahepatic bile ducts, and abnormalities of the heart,

26 The bile duct wall enhancement, intrahepatic bile ducts, and gallbladder were also evalu

27 embryonic Foxm1b -/- livers did not develop intrahepatic bile ducts, and these presumptive biliary h

28 PC, 15.61%; 95% CI, 9.21%-22.38%; P < .001), intrahepatic bile duct (APC, 8.12%; 95% CI, 4.94%-11.39%

29 In situ morphometry showed that (1) intrahepatic bile ducts are heterogeneous in external di

30 olangiocytes, the epithelial cells that line intrahepatic bile ducts, are composed of plasma membrane

31 Intrahepatic bile ducts (BD) are a critical target of in

32 Paucity of intrahepatic bile ducts (BDs) is caused by various etiol

33 ults provide direct functional evidence that intrahepatic bile ducts both secrete and absorb water in

34 Intrahepatic bile duct calculi are present in approximat

35 creatic cancer (46 000 deaths) and liver and intrahepatic bile duct cancer (41 000 deaths) surpassing

36 ondrinkers (HR=0.77; 95% CI, 0.64-0.91), and intrahepatic bile duct cancer (IHBDC) had an inverse ass

37 and 265 (0.04%) extrahepatic and 131 (0.02%) intrahepatic bile duct cancer corresponding to SIRs of 1

38 le and female individuals; and for liver and intrahepatic bile duct cancer in female individuals (2.0

39 r birth cohorts alongside IRRs for liver and intrahepatic bile duct cancer in female individuals, ute

40 Liver and intrahepatic bile duct cancer mortality increased for bo

41 ancer, 91% of ampula of Vater cancer, 96% of intrahepatic bile duct cancer, and 94% of hepatocellular

42 Small and large intrahepatic bile ducts consist of small and large chola

43 signaling as a common etiologic mechanism of intrahepatic bile duct defects in BA.

44 genetic interactions of factors important to intrahepatic bile duct development and their effect on c

45 of cirrhotic patients with tumors exhibiting intrahepatic bile duct differentiation remains controver

46 We demonstrate that tubule formation of intrahepatic bile ducts during embryonic development as

47 The cell of origin of intrahepatic bile ducts during fetal development remains

48 presence and induction of CYP1A1/1A2 within intrahepatic bile duct epithelia.

49 Chronic injury to intrahepatic bile duct epithelial cells (BDECs) elicits

50 ting of hepatocytes and cholangiocytes (i.e. intrahepatic bile duct epithelial cells).

51 e a group of hepatobiliary diseases in which intrahepatic bile duct epithelial cells, or cholangiocyt

52 fined the relationship between ICAM-1 on the intrahepatic bile duct epithelium and the evolution of N

53 ithout these infections: cancer of liver and intrahepatic bile duct; fibrosis, cirrhosis, and other l

54 le of elf3 in hepatocyte differentiation and intrahepatic bile duct formation.

55 ith risks of hepatocellular carcinoma (HCC), intrahepatic bile duct (IBD), and gallbladder and biliar

56 tin expression in cholangiocytes of isolated intrahepatic bile ducts (IBDUs) and liver cysts was anal

57 hip between adult gallbladder stem cells and intrahepatic bile duct (IHBD) cells is not well understo

58 Intrahepatic bile duct (IHBD) development produces a mor

59 erozygous mice (Jag1(+/-) ) exhibit impaired intrahepatic bile duct (IHBD) development, decreased SOX

60 The potential for intrahepatic bile duct (IHBD) regeneration in patients w

61 AGS is chiefly characterized by a paucity of intrahepatic bile ducts (IHBD), but also includes cardia

62 liver, biliary epithelial cells (BECs) line intrahepatic bile ducts (IHBDs) and are primarily respon

63 iary disease, is characterized by paucity of intrahepatic bile ducts (IHBDs).

64 c organoids lack the branching morphology of intrahepatic bile ducts (IHBDs).

65 atic bile ducts; EHBDs) or inside the liver (intrahepatic bile ducts; IHBDs).

66 Preoperative knowledge of intrahepatic bile duct (IHD) anatomy is critical for pla

67 n 11, hemorrhage in 10, fat in four, dilated intrahepatic bile ducts in 17, and abdominal lymphadenop

68 iography completely demonstrated first-order intrahepatic bile ducts in 23 (92%) patients, the donor

69 opment of strategies to block progression of intrahepatic bile duct injury in patients with BA.

70 ed hepatic IL-17A production and ameliorated intrahepatic bile duct injury.

71 entification of annexin V with predominantly intrahepatic bile ducts, is of significant interest beca

72 ive fibroinflammatory disorder of extra- and intrahepatic bile ducts, is the most common identifiable

73 isease characterised by destruction of small intrahepatic bile ducts, leading to fibrosis and potenti

74 racterized by the progressive destruction of intrahepatic bile ducts, leading to fibrosis, and potent

75 e canaliculi of hepatocytes are connected to intrahepatic bile ducts lined with cholangiocytes, which

76 llowing bile duct ligation (BDL), increasing intrahepatic bile duct mass (IBDM) and fibrosis.

77 ), GABA(B), and GABA(C) receptor expression; intrahepatic bile duct mass (IBDM) and the percentage of

78 ntrast, leptin-neutralizing antibody reduced intrahepatic bile duct mass and decreased HSC activation

79 ry proliferation was evaluated by changes in intrahepatic bile duct mass and the expression of prolif

80 Treatment with GnRH increased intrahepatic bile duct mass as well as proliferation and

81 ression and MC presence or activation; large intrahepatic bile duct mass, inflammation and senescence

82 ivo and in vitro knockdown of GnRH decreased intrahepatic bile duct mass/cholangiocyte proliferation

83 est that chronic inflammatory insults in the intrahepatic bile ducts might shed light on the cystaden

84 hepatoblasts into cholangiocytes, premature intrahepatic bile duct morphogenesis, and biliary hyperp

85 s regulating hepatoblast differentiation and intrahepatic bile duct morphogenesis.

86 in a novel cellular compartment surrounding intrahepatic bile ducts, namely portal fibroblasts.

87 orectal, breast, pancreatic, prostate, liver/intrahepatic bile duct, non-Hodgkin lymphoma, head/neck,

88 bile ducts, and its expression is reduced in intrahepatic bile ducts of patients with cholestatic dis

89 onfirmed that miR-506 is up-regulated in the intrahepatic bile ducts of PBC livers, compared with nor

90 antly inhibited the cystic dilatation of the intrahepatic bile ducts of PCK rats, which was accompani

91 demonstrated intense inflammation focused at intrahepatic bile ducts, pathology analogous to that fou

92 drome (Jag1(Ndr/Ndr) mice), characterized by intrahepatic bile duct paucity, that can spontaneously g

93 While intrahepatic bile duct proliferation is universal at dia

94 Pkhd1(del4/del4) mice develop intrahepatic bile duct proliferation with progressive cy

95 ed from BECs isolated from distinct areas of intrahepatic bile ducts revealed important functional di

96 sis is a chronic inflammatory disease of the intrahepatic bile ducts that eventually leads to liver c

97 aspase-3 staining was strongest in the small intrahepatic bile ducts, the major site of tissue destru

98 he release of bile constituents from injured intrahepatic bile ducts, thereby limiting the progressio

99 ineffective, extra-anatomical anastomoses of intrahepatic bile ducts to the gastrointestinal tract pr

100 CI, 2.75-11.49]), and APC with benign liver/intrahepatic bile duct tumors (OR, 52.01 [95% CI, 14.29-

101 erimental model, the enclosed, polarized rat intrahepatic bile duct unit (IBDU).

102 ffect of phenylephrine on lumen expansion in intrahepatic bile duct units (IBDUs) and cyclic adenosin

103 vels in cholangiocytes and duct expansion in intrahepatic bile duct units (IBDUs) in the absence or p

104 d HCO(3)(-) transport: the microperfusion of intrahepatic bile duct units (IBDUs) isolated from norma

105 in altering AQP1-mediated water transport in intrahepatic bile duct units (IBDUs) isolated from rat l

106 Small and large cholangiocytes or intrahepatic bile duct units (IBDUs) were isolated from

107 Intrahepatic bile duct units (IBDUs) were microdissected

108 orescent confocal microscopy of rat isolated intrahepatic bile duct units (IBDUs) were used to detect

109 ing purified rat cholangiocytes and perfused intrahepatic bile duct units (IBDUs), we found that TRPV

110 Secretion and cAMP levels were measured in intrahepatic bile duct units after stimulation with secr

111 A complete resection of congenital intrahepatic bile ducts was achieved in 90.5% of the 148

112 Adjacent intrahepatic bile ducts were dilated.

113 pressed in the periportal region surrounding intrahepatic bile ducts, whereas NTPDase1 was found in h

114 ing excluded owing to creation of an RYHJ to intrahepatic bile ducts with concomitant liver resection

115 rial antibodies and the destruction of small intrahepatic bile ducts with portal inflammation.

116 is involvement of both the extrahepatic and intrahepatic bile ducts, with small duct PSC being less