ライフサイエンスコーパス: intramuscular injection

1 nduction procedure (cage squeeze followed by intramuscular injection).

2 vaccination method (ie, microneedle patch vs intramuscular injection).

3 ibodies at high concentrations from a single intramuscular injection.

4 nization to RVFV in addition to conventional intramuscular injection.

5 10, and 12 weeks after a single DMPA 150 mg intramuscular injection.

6 mdx mouse and in four DMD patients by local intramuscular injection.

7 , 4 mg (n=20), or 8 mg (n=15) by needle-free intramuscular injection.

8 n be detected 14 days after subcutaneous and intramuscular injection.

9 vaccine evoked bactericidal antibodies after intramuscular injection.

10 otor neurons from the periphery following an intramuscular injection.

11 the myocardium with less injury over direct intramuscular injection.

12 s similar to or better than that elicited by intramuscular injection.

13 implanted into female mouse hearts by direct intramuscular injection.

14 0(10) viral particles or MenACWY as a single intramuscular injection.

15 , 10 and 12 weeks after a single DMPA 150 mg intramuscular injection.

16 s in a mouse model following intrajugular or intramuscular injection.

17 od to deliver cells into the heart is direct intramuscular injection.

18 e vaccines were introduced into mice through intramuscular injection.

19 ction of vaccine or placebo, administered by intramuscular injection.

20 istered to breast cancer patients by monthly intramuscular injection.

21 n cargo into spinal cord motor neurons after intramuscular injection.

22 ikely after intravenous injection than after intramuscular injection.

23 at higher levels than those by conventional intramuscular injection.

24 stable in solution and poorly absorbed after intramuscular injection.

25 nide-poisoned mice and rabbits when given by intramuscular injection.

26 r a drug that can be given quickly, e.g., by intramuscular injection.

27 responses than those elicited by traditional intramuscular injection.

28 limiting its administration to inconvenient intramuscular injections.

29 ection of acidic saline compared with pH 7.2 intramuscular injections.

30 cle is preferred over the deltoid muscle for intramuscular injections.

31 o-reporter expression in motor neurons after intramuscular injections.

32 owth hormone following intracardiac, yet not intramuscular, injection.

33 on and placebo were administered as a single intramuscular injection (1 ml) at weeks 0, 4, 8, and 20.

34 bumin or rhVEGF was administered by a single intramuscular injection (2 microg/kg body weight) to New

35 In phase 1, vaccination comprised two intramuscular injections, 21 days apart.

36 articipants were randomized 1:1 to receive 2 intramuscular injections 28 days apart (20 ug, n = 201)

37 Following intramuscular injection, a TAP fragment encoding hepatit

38 ssion when compared to concentration matched intramuscular injections, a control condition in which c

39 east as strong as delivery of the vaccine by intramuscular injection, albeit at a higher dose for top

40 h placebo (all p<0.0001) and were similar to intramuscular injection (all p>0.01).

41 ch, confers protection superior to that with intramuscular injection and enables potential dose-spari

42 pression of therapeutic levels of F.IX after intramuscular injection and is a feasible strategy for t

43 ne response to AAV capsid proteins following intramuscular injection and its impact on vector readmin

44 omparison to antigen loaded NPs delivered by intramuscular injection and soluble antigen delivered th

45 l culture, and two in vivo delivery methods (intramuscular injection and systemic intravenous injecti

46 determined the pathogenic mechanism linking intramuscular injections and provocation poliomyelitis.

47 ntly better than that seen with conventional intramuscular injection, and comparable to that observed

48 sport by spinal cord motor neurons following intramuscular injection, and exhibited both TTC- and IGF

49 79]) and pain (11 [44%] of 25 [24-65]) after intramuscular injection; and as tenderness (33 [66%] of

50 distribution studies demonstrated that after intramuscular injection, anionic liposomes offered the m

51 re <50 mm Hg received placebo or HGF-plasmid intramuscular injection as follows: 0.4 mg at days 0, 14

52 We delivered the vaccines by intramuscular injection as plasmid DNA without adjuvant

53 ts randomized to a MVA-5T4 group received an intramuscular injection at a dose of 1 x 109 50% tissue

54 edle patches were at least as immunogenic as intramuscular injection at the same dose, as demonstrate

55 mmunize mice in comparison with conventional intramuscular injection at the same dose.

56 ent groups (T1, T2, T3, and T4) and received intramuscular injections at 0, 1, 3, and 6 months (M): T

57 dure, consisting of a series of percutaneous intramuscular injections at a single timepoint, was not

58 Compared with an intramuscular injection boost, mice receiving the MNP bo

59 The in vitro and in vivo (rabbit model (intramuscular injection) burst release were similar for

60 radermal injections than among recipients of intramuscular injections, but such reactions were mild a

61 luenza vaccination via intratumoral, but not intramuscular, injection converts "cold" tumors to hot,

62 We then determined AZD8529 (.03-10 mg/kg, intramuscular injection) effects on intravenous nicotine

63 e-blind, randomized study, patients received intramuscular injections every 2 weeks of placebo or lon

64 1 or rabies vaccine (both 0.5 mL per dose by intramuscular injection), given once per month at 0, 1,

65 After a single intramuscular injection hematocrit values increased and

66 Intramuscular injection in arthritic mice of plasmid DNA

67 ith substantial tissue depots after a single intramuscular injection in BALB/cJ mice.

68 route has theoretical advantages over direct intramuscular injection in global cell dissemination int

69 unogenicity of Nanopatch immunisation versus intramuscular injection in rats, using monovalent and tr

70 dy vaccines and placebo were administered by intramuscular injection in the deltoid muscle.

71 Four weeks after intramuscular injection into mouse ischemic hindlimbs, g

72 d to the spinal cord and brainstem following intramuscular injection into the diaphragm of rats.

73 We found that intramuscular injection is always associated with a weak

74 ing of this inexpensive candidate vaccine by intramuscular injection is planned.

75 d mRNA molecules in the skeletal muscle (via intramuscular injection), lung and spleen (via intraveno

76 Recently, it has been reported that intramuscular injections may also increase the likelihoo

77 er, in contrast to mice treated with GDNF by intramuscular injection, mice receiving GDNF:TTC reveale

78 Compared to conventional intramuscular injection, microneedle vaccination resulte

79 eceived 600 micrograms vaccine or placebo by intramuscular injection monthly for 6 months then every

80 aking risperidone or paliperidone by regular intramuscular injection (n=8), and healthy comparison su

81 With intramuscular injection, no prolongation was found at th

82 to aerosolized anthrax spores, and a single intramuscular injection of 1 mg/kg of body weight fully

83 ne, when given to healthy adults as a single intramuscular injection of 1, 4, or 10 microg/serogroup,

84 We assessed the effects of a single intramuscular injection of 10 mg vitamin B-12 (which als

85 A single intramuscular injection of 100 micrograms pSK-GHRH DNA e

86 a prime-boost vaccination regime comprising intramuscular injection of 100mug CN54gp140+200mug R848

87 oporation at baseline and week 4 followed by intramuscular injection of 108 plaque forming units of M

88 f early syphilis support the use of a single intramuscular injection of 2.4 million U of benzathine p

89 lactating Holstein cows after a single dose intramuscular injection of 2.50 g of all-rac-alpha-tocop

90 Intramuscular injection of 3 doses of quadrivalent HPV v

91 All participants received intramuscular injection of 4 mg vaccine.

92 Following the intramuscular injection of 5% hypertonic saline, 49% of

93 After intramuscular injection of 5, 10, and 20 x 10(6) myoblas

94 kg during days 8 to 10 (group 4), and daily intramuscular injection of 5.0 mg of ceftiofur hydrochlo

95 Intramuscular injection of 6 mg/kg xylazine induced an i

96 Twenty-four hours after a single intramuscular injection of [3H]thymidine, labeled cells

97 myofibers were intensely blue following the intramuscular injection of a beta-galactosidase expressi

98 Intramuscular injection of a clostridial toxin preparati

99 disease in mice and hemophilic dogs through intramuscular injection of a recombinant adeno-associate

100 In this study, we demonstrate that a single intramuscular injection of a recombinant adeno-associate

101 We sought to determine whether intramuscular injection of a recombinant adeno-associate

102 Towards this objective, we show that intramuscular injection of a replication-incompetent, re

103 e side only of the spinal cord by unilateral intramuscular injection of a retrogradely transported fo

104 A single intramuscular injection of a self-replicating RNA immuno

105 ng a nonsense mutation, can be skipped after intramuscular injection of a specific 2'-O-methyl phosph

106 muscular injection of AFV (10 ug; n = 4), or intramuscular injection of AAV (10 ug; n = 4).

107 exaggerate the immune response induced after intramuscular injection of AAV serotype 2 vector.

108 s, we examined immune responses to FIX after intramuscular injection of AAV with simultaneous activat

109 y transferred into mice that had received an intramuscular injection of AAV-lacZ 10 days earlier.

110 ruitment and activation of DCs subsequent to intramuscular injection of AAV.

111 In addition, inhibiting myostatin using intramuscular injection of AAV1-follistatin ameliorates

112 ependent of the cAMP pathway by 1 week after intramuscular injection of acid.

113 Intramuscular injection of AdCA5 into the ischemic limb

114 enting HIF-1alpha levels in ischemic limb by intramuscular injection of AdCA5, an adenovirus encoding

115 nce to coagulation factor IX (FIX) by direct intramuscular injection of adeno-associated virus (AAV)-

116 of TIPE2 in muscular dystrophy, we performed intramuscular injection of adeno-associated virus 9 carr

117 When R333Q-hFIX mice were challenged by intramuscular injection of adeno-associated virus expres

118 We show that intramuscular injection of adeno-associated virus seroty

119 of recombinant adenoviruses, and boosted by intramuscular injection of adjuvanted F and G proteins,

120 ere is universal expert agreement that rapid intramuscular injection of adrenaline is life-saving and

121 naphylactic shock, which was relieved by the intramuscular injection of adrenaline.

122 24 +/- 8 ug (n = 4) or 48 +/- 14 ug (n = 4), intramuscular injection of AFV (10 ug; n = 4), or intram

123 Intramuscular injection of alpha-syn fibrils in the hind

124 toxin-neutralizing antibody titers than did intramuscular injection of alum-adsorbed rPA.

125 d toxicity, we initiated a clinical study of intramuscular injection of an AAV vector expressing huma

126 Recent studies have shown that intramuscular injection of an adeno-associated viral (AA

127 We performed intramuscular injection of an adeno-associated virus (AA

128 been supplemented for this growth factor via intramuscular injection of an adenoviral vector encoding

129 Intramuscular injection of an adenovirus encoding domina

130 Intramuscular injection of an inflammatory irritant, mus

131 Intramuscular injection of an unadjuvanted HIV-1 envelop

132 Preclinical studies provide evidence that intramuscular injection of autologous CD34+ cells improv

133 Intramuscular injection of BALB/c mice with a DNA plasmi

134 We show that intramuscular injection of BCG reduced by 76% (Odds rati

135 Subcutaneous or intramuscular injection of both conjugates elicited a 50

136 Intramuscular injection of Botox resulted in a significa

137 We prevented limb use by the intramuscular injection of botulinum toxin A into select

138 the final regression model, subcutaneous or intramuscular injection of BTH was the only behavior ass

139 enuates masseter hypersensitivity induced by intramuscular injection of capsaicin.

140 s medialis muscle were selectively killed by intramuscular injection of cholera toxin-conjugated sapo

141 ical signs of impaired cobalamin function, 1 intramuscular injection of cobalamin resulted in biochem

142 Direct intramuscular injection of compound RTC14 did not result

143 In two baboons studied, the intramuscular injection of CVF (0.25 mg/kg) was followed

144 Intramuscular injection of dexamethasone had a profound

145 They received a single 75-mg (3 mL) intramuscular injection of diclofenac (n = 27) or simila

146 One intramuscular injection of dMAb produced antibodies in v

147 Intramuscular injection of DNA plasmids produced a diffe

148 Intramuscular injection of DNA vaccines elicits potent h

149 Intramuscular injection of DTX caused cytopathology in m

150 Focal infection was induced in rats by an intramuscular injection of E. Coli in the right thigh.

151 randomly assigned to receive a single 0.5-mL intramuscular injection of either V710 vaccine, 60 mug (

152 s were randomly assigned to receive a single intramuscular injection of either vaccine or saline.

153 measure local blood flow at the site of the intramuscular injection of exotoxins from an invasive M-

154 were retrogradely labeled after percutaneous intramuscular injection of Fluorogold (FG) into the EAS.

155 were retrogradely labelled in adult rats by intramuscular injection of Fluorogold and examined with

156 As compared with an intramuscular injection of full-dose influenza vaccine,

157 atients were randomized to receive either an intramuscular injection of fulvestrant 250 mg once month

158 dministered DATS orally and/or given a local intramuscular injection of green fluorescent protein-lab

159 The Study to Assess the Safety of Intramuscular Injection of Hepatocyte Growth Factor Plas

160 hat modulating satellite cell quiescence via intramuscular injection of HGF increases the penetrance

161 Intramuscular injection of HGF plasmid was safe and well

162 A single intramuscular injection of IGF-1, but not PBS, markedly

163 e EGG recording was started 20 minutes after intramuscular injection of ketamine and azaperone (perio

164 normal human F.IX levels) can be reached by intramuscular injection of mice using a 2- to 4-fold low

165 Intramuscular injection of mice with an adeno-associated

166 However, an intramuscular injection of minute amounts of BoNTs, prim

167 ocytic sarcoma could be similarly induced by intramuscular injection of MLL-AF9 leukemia cells.

168 Intramuscular injection of MuLE viruses expressing oncog

169 1 or vehicle was administered for 3 weeks by intramuscular injection of murine ischemic hindlimbs.

170 red human TIMP-4 by electroporation-mediated intramuscular injection of naked DNA using the rat adjuv

171 y be cautiously interpreted to indicate that intramuscular injection of naked plasmid DNA achieves co

172 h levels of foreign gene expression from the intramuscular injection of naked plasmid DNA in mice and

173 Intramuscular injection of Nano-11-antigen formulations

174 Intramuscular injection of nonautologous MSCs can be saf

175 Here we report that intramuscular injection of nonreplicating recombinant ad

176 A single intramuscular injection of pCBWN DNA induced protective

177 Intramuscular injection of pDNA encoding GAD65-IgGFc and

178 infected adults were randomized to receive 1 intramuscular injection of placebo (n=6) or vaccine at d

179 We have previously shown that intramuscular injection of plasmid DNA encoding the nucl

180 Direct intramuscular injection of PNA-ssODNs targeting the mdx(

181 ' duration were treated with either a single intramuscular injection of polyethylene glycol-modified

182 A single 10 mg intramuscular injection of pSP-HV-GHRH DNA followed by e

183 table transgene expression in mice following intramuscular injection of purified recombinant AAV (rAA

184 ly diagnosed NOD mice were provided a single intramuscular injection of recombinant adeno-associated

185 on-sarcoglycan, was fully restored following intramuscular injection of recombinant delta-sarcoglycan

186 er amounts of dystrophin were detected after intramuscular injection of RTC13.

187 Intramuscular injection of ssGnih-3 provoked a significa

188 Intramuscular injection of succinate also significantly

189 Intramuscular injection of superantigen plasmid DNA in v

190 e, an effect that could not be reproduced by intramuscular injection of superantigen protein.

191 same order of magnitude as those produced by intramuscular injection of the commercially available re

192 Subcutaneous or intramuscular injection of the conjugates elicited a 28-

193 Intramuscular injection of the higher-dose of AVI-4658 r

194 ially induce a stronger immune response than intramuscular injection of the same plasmid DNA.

195 nt of the usual dose), and 119 to receive an intramuscular injection of the standard dose of 15 mug o

196 s by a factor of 14.9, 7.1, and 15.3 for the intramuscular injection of the standard dose.

197 icles induced comparable immune responses as intramuscular injection of them, but transcutaneous immu

198 Electroporation-mediated intramuscular injection of TIMP-4 expression plasmid res

199 pleural injection of talc (400 mg/kg) and an intramuscular injection of triamcinolone (0.8 mg/kg) 1 d

200 n = 20) in a randomized fashion, followed by intramuscular injection of trivalent influenza vaccine 1

201 Local inflammation induced by the intramuscular injection of turpentine (50 microl/100 gm

202 male Swiss-Webster mice received a 20-microL intramuscular injection of turpentine into the right thi

203 sterile soft-tissue inflammation induced by intramuscular injection of turpentine.

204 in vivo regulation of gene expression after intramuscular injection of two separate adenovirus or ad

205 luated T-cell responses to AAV capsids after intramuscular injection of vectors into mice and nonhuma

206 per limit of the reference value received an intramuscular injection of vitamin K.

207 and, 4 wk postinoculation (WPI) treated with intramuscular injections of 10 mg kg(-1) wk(-1) ActRIIB.

208 [HRT]; men: testosterone enanthate, biweekly intramuscular injections of 100 mg) (n = 35); GH + place

209 laria-naive volunteers were immunized with 3 intramuscular injections of 20 mug (n = 9) or 50 mug (n

210 Patients also received twice weekly intramuscular injections of 20 mug/kg poly-ICLC.

211 with twin gestations were assigned to weekly intramuscular injections of 250 mg of 17P or matching pl

212 oids and randomly assigned to receive weekly intramuscular injections of 30 microg interferon beta-1a

213 nts were randomly assigned to receive weekly intramuscular injections of 30 microg of interferon beta

214 Each volunteer received 3 spaced intramuscular injections of 50 microg (n = 8), 100 micro

215 0.4 microg of DNA and boosted intradermal or intramuscular injections of 50 microg of DNA failed to p

216 Participants received three intramuscular injections of 85 mug vaccine (with adjuvan

217 duction of any neuronal protein and supports intramuscular injections of a small interfering RNA-enco

218 Intramuscular injections of Ad-PlGF-1 significantly incr

219 Intramuscular injections of Alhydrogel (plus CpG) adjuva

220 ocked for at least several hours after daily intramuscular injections of alpha-bungarotoxin.

221 n were made before and for 39 weeks after 11 intramuscular injections of ALT-711 at 1.0 mg/kg body we

222 udy, we evaluated the safety and efficacy of intramuscular injections of autologous CD34+ cells in su

223 Intramuscular injections of botulinum toxin A reduce spa

224 ation of stroke, and it is uncertain whether intramuscular injections of botulinum toxin type A reduc

225 Intramuscular injections of compound 41 (the decanoate e

226 The animals were treated with daily intramuscular injections of CsA using doses selected to

227 Intramuscular injections of DCZ (100 mug per kg) reversi

228 t chinchillas received three subcutaneous or intramuscular injections of dLOS-conjugated tetanus toxo

229 Intramuscular injections of DNA encoding the CR1 genes p

230 Mice receiving two intramuscular injections of expression plasmid (50 micro

231 ere identified using retrograde labeling via intramuscular injections of Fast Blue or Fluoro Gold, re

232 Intramuscular injections of haloperidol decanoate 25 to

233 Vaccine recipients received 3 intramuscular injections of HIV DNA (4 mg) coding for cl

234 ose of either 5 mg or 10 mg) or once-monthly intramuscular injections of leuprolide acetate (at a dos

235 t period and, after safety assessment, three intramuscular injections of long-acting cabotegravir 800

236 Seventy-two participants received 1 or 2 intramuscular injections of low-dose (LD; 5 x 1010 vecto

237 domly assigned in a 1:1 ratio to receive two intramuscular injections of mRNA-1273 (100 mug) or place

238 uman recombinant IL-2 (PEG-IL-2) or multiple intramuscular injections of murine recombinant IL-12; un

239 Intramuscular injections of NT3 to Egr3-/- mice during t

240 Two patients who had been treated with intramuscular injections of pegylated bovine ADA (PEG-AD

241 We evaluated whether intramuscular injections of plasmids with cDNA encoding

242 s were randomly assigned (2:1) to receive 13 intramuscular injections of recMAGE-A3 with AS15 immunos

243 We then performed in vivo intramuscular injections of recombinant adeno-associated

244 Intramuscular injections of saline (n = 3) or insulin (n

245 Intramuscular injections of Tetanus Toxin C-fragment (TT

246 Overall, the intramuscular injections of the drug exerted salutary ef

247 therapy, each subject received at least four intramuscular injections of the vaccines on days 0, 30,

248 Patients received eight intramuscular injections of their assigned treatment in

249 Intramuscular injections of Triplex or placebo were give

250 two visits 21 days apart, subjects received intramuscular injections of vaccine that contained 0.48

251 igned (1:1:1) to receive fulvestrant (500 mg intramuscular injection on day 1, followed by 250 mg dos

252 over 28-day cycles) plus 500 mg fulvestrant (intramuscular injection on days 1 and 15 of cycle 1; the

253 ine or the qHPV vaccine in a series of three intramuscular injections on day 1 and at months 2 and 6.

254 ndomly assigned (1:1) to fulvestrant (500 mg intramuscular injection; on days 0, 14, 28, then every 2

255 ate, 100 mg (n = 14), or placebo (n = 15) by intramuscular injection once a week for 6 months.

256 d to receive either fulvestrant (250 mg, via intramuscular injection, once monthly; n = 313) or tamox

257 of rAd5-based vectors after either a single intramuscular injection or a DNA prime/rAd boost.

258 DNA vaccines are usually given by intramuscular injection or by gene gun delivery of DNA-c

259 zed either systemically with H7 flagellin by intramuscular injection or mucosally via the rectum with

260 ring the immunogenicity of IPV2 delivered by intramuscular injection or Nanopatch immunisation.

261 e nirsevimab, at a dose of 50 mg in a single intramuscular injection, or placebo at the start of an R

262 e strain) (1) by microneedle patch or (2) by intramuscular injection, or received (3) placebo by micr

263 are worker administered microneedle patch or intramuscular injection, or self-administered microneedl

264 and block sizes of 2 and 2 to receive three intramuscular injections over 6 months of 9vHPV or qHPV

265 Intramuscular injection provides more rapid and higher p

266 or house-to-house vaccination campaigns (the intramuscular injections require health professionals),

267 igher level of hFIX compared to tail vein or intramuscular injections, respectively.

268 Factor IX gene to skeletal muscle by direct intramuscular injection resulted in therapeutic levels o

269 Intramuscular injections resulted in low expression of a

270 nt with IFNbeta-1a, 30 microg once weekly by intramuscular injection, resulted in a significant decre

271 vitro, as well as in its elimination at the intramuscular injection site in vivo during mixed infect

272 By intramuscular injection, species D vaccines were markedl

273 tical properties and must be administered by intramuscular injections that limit the total amount of

274 humoral and cellular immune responses, after intramuscular injection the DNA vector encoding the Sc-G

275 rypsin (rAAV-hAAT) vectors were delivered by intramuscular injection to either C57BL/6 (DNA-PKcs(+))

276 al particles) or placebo, administered by 20 intramuscular injections to each leg.

277 U) AdVEGF121, or placebo, administered as 20 intramuscular injections to the index leg in a single se

278 ver, nonreplicating vaccines administered by intramuscular injection using a syringe and needle elici

279 current inactivated vaccines administered by intramuscular injection using a syringe and needle elici

280 XR-NTX was monthly intramuscular injections (Vivitrol; Alkermes) and BUP-NX

281 tivated influenza vaccine (TIV) licensed for intramuscular injection was compared with that of trival

282 s formulations over a period of 28days after intramuscular injection was evaluated by the observed in

283 causal prophylactic antimalarial activity by intramuscular injection, was previously prepared by trea

284 net removal, OTR4120 was administered via an intramuscular injection weekly for up to 4 weeks.

285 Intramuscular injections were distributed into 8 sites w

286 sal secretions and sera than in animals with intramuscular injection, which showed stronger systemic

287 to protective antigen 14 days after a single intramuscular injection, which were further increased up

288 Pigs in group 3 were vaccinated by intramuscular injection with 10(3.5) 50% tissue culture

289 Pigs in group 1 were vaccinated by intramuscular injection with 200 microg of the chimeric

290 Antimicrobial treatments included daily intramuscular injection with 66,000 IU of procaine penic

291 Five horses were immunized by direct intramuscular injection with a mixture of retroviral vec

292 either by intramuscular needle injection, by intramuscular injection with a needleless injection devi

293 Although other muscles atrophy after intramuscular injection with Botox, extraocular muscles

294 Priming was performed via intramuscular injection with gag and env DNA adsorbed to

295 t velocities of jaw opening before and after intramuscular injection with hypertonic saline (HS, 5%,

296 ged than that we had observed after a single intramuscular injection with inactivated influenza vacci

297 infection were randomly assigned to receive intramuscular injection with rAAV1-PG9DP or placebo in t

298 Intramuscular injections with 10(8) CFU of the LHBc-NEO(

299 cocorticosteroids intravenously, followed by intramuscular injections with a cumulative dose of 3.24

300 Mice were immunized by intramuscular injections with a eukaryotic expression ve