ライフサイエンスコーパス: intricate

1 logic conditions, and their signaling can be intricate.

2 ist of folded origami sheets or modules with intricate 3D geometries, and feature many unique and des

3 n of proteins and lipids, our method reveals intricate 3D organizations of tumor spheroids, mouse bra

4 This interaction is regulated by an intricate allosteric mechanism.

5 KM2 and offer a broader understanding of its intricate allosteric regulation mechanism by phosphoryla

6 se or human patients, in Drosophila allowing intricate analysis of the PCP pathway.

7 em (CNS) development and function require an intricate and balanced bidirectional communication betwe

8 we discuss emerging and exciting evidence of intricate and crucial connections between the gut microb

9 Particularly intricate and fine-scale features characterize the so-ca

10 The intricate and interconnecting reactions of C(3) photosyn

11 esults provide a deeper understanding of the intricate and multifaceted set of regulatory mechanisms

12 interlocking mechanism, we also consider the intricate and striking multiscale-patterned edge in cert

13 Pathogens rely on an intricate and synergistic antioxidant armamentarium that

14 ADP-ribosylation is an intricate and versatile posttranslational modification i

15 f genome architecture and gene expression is intricate, and its molecular mechanisms are under intens

16 striatal connections in rodents emphasize an intricate architecture where striatal projections origin

17 e regions responsible for orchestrating this intricate architecture.

18 spontaneously assemble from solution into an intricate arrangement of cells within a conductive polym

19 However, multicolor detection requires an intricate arrangement of multiple detectors and meticulo

20 The intricate arrangement of numerous and closely placed chr

21 ules at near-atomic resolution, revealing an intricate array of proteins decorating the inner and out

22 uman EMC cryo-EM structures reveal conserved intricate assemblies and human-specific features associa

23 s are still needed to fully understand their intricate atomic structures.

24 either in the light or dark, depends on the intricate balance between cell division and differentiat

25 readers with the nucleosome that provides an intricate balance between cooperative and individual act

26 ates mitochondrial fusion by coordinating an intricate balance between Fzo1 turnover and the status o

27 Herein, we postulate that an intricate balance between immunostimulatory and inhibito

28 comprising ~35 monomeric units, revealing an intricate balance between intramolecular and intermolecu

29 is generally depicted as a consequence of an intricate balance between pulling forces actuated by the

30 The intricate balance between self-renewal and differentiati

31 structural distortions and defects, and the intricate balance of competing interactions which emerge

32 Emerging evidence suggests that the intricate balance of interactions between neurons, astro

33 hway has achieved limited success due to the intricate balance of its different components and isofor

34 alkalinization factors (RALFs), engage in an intricate balancing act involving autocrine and paracrin

35 tral role of secreted polysaccharides in the intricate behaviors coordinating bacterial multicellular

36 e considered peptides, each stabilised by an intricate, bespoke arrangement of disulphide bonds.

37 Protein-protein interactions featuring intricate binding epitopes remain challenging targets fo

38 p the technical possibilities to unravel the intricate biology of Wnt signaling and Wnt-receptor sele

39 onal imaging modalities are unable to access intricate biomolecular information without compromising

40 ese findings offer fresh perspectives on the intricate biophotonic interplay between pigmentary and s

41 ved across significant distances and that an intricate botanical knowledge was intrinsic to pre-Colum

42 pathways to prebiotic systems evolution more intricate, but were surely essential for sustaining far-

43 bring further insights into the synthesis of intricate carbohydrate derivatives, achieved with the ai

44 The complement system is an intricate cascade of the innate immune system and plays

45 benzo[ de]chromenes are obtained through an intricate cascade process comprising unusual formal [4 +

46 This approach is demonstrated by fabricating intricate cell patterns with pre-defined features throug

47 g a complex brain requires many neurons with intricate cell specificity, generated by a limited numbe

48 EndMT is an intricate cellular differentiation process whereby endot

49 A greater knowledge of the intricate cellular milieu of the heart is critical to in

50 ycoconjugate vaccines are manufactured using intricate chemical methodologies to covalently attach pu

51 osphatase plays a key role in organising the intricate choreography of mitosis and cell division.

52 the spliceosome in action to illustrate the intricate choreography of splicing.

53 ems exploit self-assembly to generate highly intricate closed supramolecular architectures, ranging f

54 hosts is an excellent model for decoding the intricate coevolutionary processes of host-pathogen inte

55 Eukaryotic cells represent an intricate collaboration between multiple genomes, even d

56 An intricate combination of conformational changes occurs i

57 les in legume-rhizobia symbiosis requires an intricate communication between the host plant and its s

58 Tails are an intricate component of the locomotor system for many ver

59 , has captured scholarly interest due to its intricate composition and social implications.

60 This study further clarifies the intricate connection between Q(6) biosynthesis, traffick

61 BS-seq) data revealed interrelationships and intricate connections among R-loops, gene expression, an

62 is in Drosophila and started to untangle the intricate connections between core anabolic processes an

63 ought role for ORAI2 and ORAI3, revealing an intricate control mechanism whereby heteromerization of

64 threshold switching devices rely heavily on intricate control of material stoichiometry and generall

65 d deubiquitination cycle and demonstrate the intricate control that Legionella has over this unusual

66 Our results point toward an intricate coupling between the dynamics of the active-si

67 Intricate cross talk between these diverse cell types is

68 Spermatogenesis is supported by intricate crosstalk between Sertoli cells and germ cells

69 These data reveal intricate crosstalk between the germ line and the epigen

70 oporins, assemble in multiple copies into an intricate cylindrical architecture.

71 The spatial variations of the intricate cytoarchitecture, fluid scalae, and mechano-el

72 To address this intricate data situation, we provide an integrated resou

73 framework since such amplifiers require the intricate design of DNA sequences and reaction condition

74 nduction and energy storage, and discuss the intricate design principles that enable these COFs to pe

75 rapid and cost-effective customization with intricate designs along with scalability is enabled by m

76 Practical obstacles, such as intricate designs and expensive equipment/materials, in

77 ctures is currently limited, which restricts intricate designs and the complexity of functions perfor

78 es as an excellent system to investigate the intricate details of development and differentiation.

79 The intricate details of how proteins bind to proteins, DNA,

80 provides new opportunities to understand the intricate details of protein complexes such as the impac

81 High-resolution structures have revealed intricate details of the interactions of the capsid (CA)

82 DFT calculations revealed intricate details of the reaction mechanisms, and strong

83 , we review the current understanding of the intricate dialog between cancer-associated inflammation

84 g body of experimental work has revealed the intricate, diverse, and dynamic roles that epigenetic mo

85 Correspondingly, cells have evolved intricate DNA repair systems to deter changes to their g

86 ly regulated at promoter-proximal regions by intricate dynamic processes including Pol II pausing, re

87 ntia, which might lead to a breakdown of the intricate dynamic properties of the brain, thereby causi

88 However, human tumors are intricate ecosystems composed of diverse cells, includin

89 l redox-active cofactors that participate in intricate electron transfer pathways there are two tyros

90 Microbes employ a remarkably intricate electron transport system to extract energy fr

91 substrate nutrient availability resulted in intricate elemental distribution patterns.

92 Overall, our study reveals intricate epidemiological interactions and underscores t

93 These findings underscore the intricate exchange of information and coordination of bo

94 ions within the cancer itself likely involve intricate feedbacks, and no single component can explain

95 ticles inside microfluidic channels exhibits intricate focusing dynamics.

96 The structure reveals the intricate fold of the 584 kDa protein, comprising an N-t

97 ar assist device (LVAD) implantation require intricate follow-up and complex care.

98 brain's structural scaffold give rise to its intricate functional dynamics?

99 s on this dimerization mechanism underlie an intricate gene regulation network at physiological condi

100 Understanding the functioning of this intricate genetic regulatory network provides new insigh

101 cal signaling, and chemical sensors to build intricate geometrical structures and perform complex beh

102 ncer prevention trial, and insights into the intricate germline-somatic-immunity interaction landscap

103 Female sage-grouse exhibited intricate habitat selection patterns that varied across

104 Because of their intricate helical structure, new properties of CLC have

105 ions enable assembly of colloidal rafts into intricate higher-order architectures, including stable t

106 residues, Glu1044, Arg1088, Arg1091, form an intricate hydrogen bond network with the first cytosine

107 The dimer-dimer interface requires an intricate hydrogen bonding network involving residues R4

108 f all other amino acid residues and revealed intricate hydrogen-bonding networks in the active-site c

109 traced to the participation of Glu-818 in an intricate hydrogen-bonding/salt-bridge network, connecti

110 Our study uncovers an intricate IBC-initiated autocrine-paracrine signaling ne

111 bsence of nasal polyps belies the underlying intricate immunopathophysiological processes responsible

112 They form extended networks and exhibit an intricate inner membrane architecture.

113 rough epigenetic processes, highlighting the intricate interaction between genetic and epigenetic con

114 This study highlights the intricate interactions between antibodies and innate imm

115 the first time, a detailed assessment of the intricate interactions between DGK and ENaC and is consi

116 Additional studies have revealed intricate interactions between different IEL subsets, re

117 Mammalian embryogenesis requires intricate interactions between embryonic and extraembryo

118 n and molecular mechanisms that underlie the intricate interactions between miRNAs and ATM.

119 an brain, and allow the investigation of the intricate interactions between resident neural and glial

120 llows bonds to break and form, capturing the intricate interactions between the hydrated excess proto

121 r-red light by bacteriophytochromes involves intricate interactions between their bilin chromophore a

122 affect the formulation properties, and their intricate interactions have been difficult to decipher.

123 The intricate interactions the parasite Plasmodium falciparu

124 erize, and are taken up by cells, depends on intricate interactions with extracellular matrix molecul

125 A200 unique architecture; the details of its intricate interactions with the proteasome, resulting in

126 h considerable relative importance and their intricate interactions.

127 The cerebral cortex of mammals exhibits intricate interareal wiring.

128 s) and tumour-adjacent cells (TACs), and the intricate interconnections between these diverse populat

129 tween widely fluctuating external inputs and intricate internal structures.

130 lend morphologies, which are a result of the intricate interplay among materials crystallinity, phase

131 e site selection in LMNA is determined by an intricate interplay among RNA sequence, secondary struct

132 cting polymer membranes is complicated by an intricate interplay between chemistry and morphology tha

133 Overall, our findings uncover the intricate interplay between CpG-flanking sequence, DNMT1

134 Taken together, our data unveil the intricate interplay between intronic miRNA and their hos

135 ur of multicomponent lipid bilayers found an intricate interplay between membrane geometry and its co

136 e subcellular dynamics of aSyn and unveil an intricate interplay between subcellular location, phosph

137 g ratio at 300 K, which is attributed to the intricate interplay between the charge screening at the

138 ty and longitudinal conductivity reveals the intricate interplay between the spin-dependent impurity

139 er of individual structural units and by the intricate interplay between them.

140 romising in the clinical exploitation of the intricate interplay of HIFs, angiogenesis, and metabolis

141 ting strips and bridges are determined by an intricate interplay of surface and bulk pinning.

142 eir individual roles and shed light on their intricate interplay.

143 n the alterations in digester microbiome and intricate interspecies networks during substrate variati

144 t along microtubules and helps elucidate the intricate intracellular sorting observed in highly polar

145 y packed together in the center of C1 and an intricate intramolecular reaction mechanism for activati

146 two reconstituted transporters recapitulates intricate kinetics behaviour observed in vivo.

147 lant cell internal environment is a dynamic, intricate landscape composed of many intracellular compa

148 The intricate lattice of Gn and Gc glycoprotein spike comple

149 w the structure laterally aggregates to form intricate lattices together with the gamma-chain.

150 Intricate life-versus-death decisions are programmed dur

151 Intricate lineage-tracing strategies and experimental mo

152 An intricate link is becoming apparent between metabolism a

153 Even if constructed, probing their intricate linkages and topological "drumhead" surface st

154 hampered due to the formation of complex and intricate long-range base-pairing interactions which mak

155 herefore, this review was written to take an intricate look at the involvement of Th17 cells and thei

156 Microbial populations form intricate macroscopic colonies with diverse morphologies

157 ononic waveguides remain elusive, preventing intricate manipulation of phonons on par with its photon

158 Since our modifications do not impose intricate manufacturing, require long post-processing, n

159 om infected hepatocytes are the result of an intricate maturation process that starts with the format

160 t regulator of striatal functions through an intricate mechanism involving RhoA and culminating in Kv

161 ese results improve the understanding of the intricate mechanism of BDNF transcriptional autoregulati

162 This repressive complex acts as part of an intricate mechanism of preferred nutrient utilisation.

163 Here, we revealed an intricate mechanism of TRPV1-ANO1 channel coupling in ra

164 However, the intricate mechanisms and the large degrees of freedom of

165 These observations highlight the intricate mechanisms by which expression of genes that e

166 specific DNA sequences through a variety of intricate mechanisms that lie on a continuum between lar

167 s the gastrointestinal tract and has evolved intricate mechanisms to sense and respond to the host en

168 Intracellular pathogens have evolved intricate mechanisms to subvert host cell signaling path

169 Meanwhile, intricate membrane design to realize synergistic separat

170 ty of heterotrophic microorganisms, creating intricate metabolic networks that determine the extent o

171 The formation of intricate microarchitectures typically requires sophisti

172 d how cellular microenvironments composed of intricate microfibrillar networks influence cell fate de

173 Here, we report the characterization of the intricate midbody protein-protein interaction network (i

174 This intricate modulation of binding affinity, and thus coope

175 stem to synthesize 80 diverse compounds with intricate molecular architectures.

176 hesion strength at high shear stress through intricate molecular mechanisms including dual-binding mo

177 oadly accessible and yet incorporates highly intricate molecular recognition, immolative, and rearran

178 le, which might facilitate understanding the intricate molecular regulation of shell color polymorphi

179 potential for the synthesis of structurally intricate molecules.

180 licated, not only due to the ill-defined and intricate morphological and mesoscopic structure of elec

181 races with their pollinators that result in intricate morphologies in both parties, and flowers with

182 or microglia in each brain, revealing their intricate morphologies.

183 es of biogenic silica in the ocean and their intricate morphology is an inspiration for nanoengineeri

184 ex relationships between multiple species in intricate natural ecological networks.

185 rms within the tertiary twins, revealing the intricate nature of coupling between deformation twinnin

186 ein homeostasis in murine P19 cells using an intricate negative feedback mechanism.

187 to a patchwork of flattened vesicles, via an intricate network composed of alveolins.

188 f ECM (extracellular matrix) and requires an intricate network of blood and lymphatic vessels and ner

189 The human visual system is an intricate network of brain regions that enables us to re

190 l grows from a single fertilized egg into an intricate network of cell types and organ systems.

191 Our findings thus unveil an intricate network of evolutionarily conserved protein-pr

192 TT form an intricate network of fluid-filled conduits that support

193 Thus, an intricate network of host-pathogen interactions promotes

194 Our structure reveals an intricate network of interactions between CDK7 and its t

195 neurons whose activity is coordinated by an intricate network of interneurons.

196 lies on the enteric nervous system (ENS), an intricate network of more than 500 million neurons and s

197 and NMR reveal a folding pattern based on an intricate network of noncovalent interactions involving

198 memories of these events are organized in an intricate network of overlapping associated events.

199 organ providing tissue perfusion through an intricate network of penetrating small vessels.

200 organ, and organism homeostasis relies on an intricate network of players and mechanisms that assist

201 We observe multistability and explore an intricate network of regime shifts between stable states

202 ificity and revealed known components of the intricate network of systems that underwrite [NiFe]-hydr

203 lts demonstrate an evolutionarily conserved, intricate network of transcriptional control of the mamm

204 Here, the configuration is stabilized by an intricate network of two distinct yet interconnected hel

205 appears to be a process characterized by an intricate network that involves many transcription facto

206 ically do not provide a complete view of the intricate networks through which chaperones collaborate

207 A complex brain consists of multiple intricate neural networks assembled from distinct sets o

208 gap out this magnon spectrum resulting in an intricate nuclear magnetism.

209 Facing this intricate optimization problem, school districts must re

210 Their intricate organization emerges from competing chirality-

211 allowed researchers to gain insight into the intricate organization of the mammalian brain and the ro

212 the physics-based hurricane projections and intricate outage risk models.

213 al and clinical approaches used to untie the intricate pancreas-microbiota cross talk.

214 After entering the leaf, CO(2) faces an intricate pathway to the site of photosynthetic fixation

215 f its interaction partners are arranged into intricate patterns in human and yeast mitochondria, sugg

216 Intricate patterns of cell shape can be analyzed and cla

217 gical order and are instead characterized by intricate patterns of entanglement(3,4).

218 and act to regulate various branches of the intricate phenylpropanoid pathway.

219 ion and DNA-binding mode of WRKY TFs, and an intricate picture of the WRKY/W-box DNA recognition.

220 nidine-type diterpenoid alkaloids feature an intricate polycyclic, bridged framework with unusual con

221 (4) )(8) }S(6) ](6-) , which functions as an intricate polyhedral template with abundant surface O an

222 However, their often-small size and intricate post-translational biogenesis preclude the use

223 Thus, our study reveals an intricate post-translational network that negatively reg

224 Virus infection is an intricate process that requires the concerted action of

225 Viral infection is an intricate process that requires the concerted action of

226 mbly of chiral supramolecular polymers is an intricate process that spans a wide range of length scal

227 Understanding how these intricate processes interconnect at the cellular level i

228 5'SS-ACAGAGA helix triggers remodeling of an intricate protein-RNA network to induce Brr2 helicase re

229 a cell density-dependent manner by using an intricate quorum-sensing (QS) network.

230 An intricate radical cyclization of a late stage intermedia

231 To get insight into the mechanism of these intricate reactions, we constructed an artificial reacti

232 he catalysis community to build increasingly intricate, realistic, and accurate models of the active

233 The detailed architecture of this intricate recombination machine remains unclear.

234 fy key biosynthetic intermediates and expose intricate redox tailoring steps for the formation of ris

235 Recent studies have revealed intricate regulation of all steps of HR by the protein m

236 ullin and RING proteins, many unexpected and intricate regulatory mechanisms have emerged.

237 the alternative front layer, but rather the intricate relation between front layer processing and el

238 Collectively, our study describes an intricate relationship between cellular targets of an RN

239 Mounting evidence points to an intricate relationship between DSBs and transcription.

240 ur findings provide further insight into the intricate relationship between host and bacterial metabo

241 a changes as the host ages, but also how the intricate relationship between host and indigenous bacte

242 s, specifically TIM-family proteins, and the intricate relationship between host and viral factors.

243 Together, our results reveal the intricate relationship between macronutrient intake and

244 numa et al. (2017) provide insights into the intricate relationship between metabolism and morphogene

245 c devices, a central topic is to clarify the intricate relationship between the resonance spectrum an

246 We discuss the intricate relationship between the yolk sac and the prim

247 sms and their natural viruses may lead to an intricate relationship in which host survival requires e

248 Here, an intricate relationship is proposed between these multipl

249 eraction profile of several GPCRs hint at an intricate relationship of these receptors with their sur

250 Insights from the study of the intricate relationships between immune cells and cancer

251 to systematically measure and visualize the intricate relationships between intracellular signaling,

252 thogens can balance their virulence and form intricate relationships with their hosts.

253 ly sensitive and selective in small value of intricate RNA samples.

254 ur findings suggest miR487b editing plays an intricate role in postischemic neovascularization.

255 lusion, histone methylation dynamics play an intricate role in the fine-tuning of chromatin states du

256 ctional characterization of human tRNAs with intricate roles in various cellular states.

257 Here, we reveal that the intricate scale layer on moth wings forms a metamaterial

258 Existing approaches to these structurally intricate secondary metabolites are discussed in the con

259 Bacteria have evolved intricate secretion machineries for the successful deliv

260 A key finding of these studies is that intricate sequences of pursuit and evasion behavior can

261 The intricate shapes of biological membranes such as tubules

262 alignant brain tumor, have been defined, the intricate signaling networks associated with these alter

263 An array of photoreceptors and intricate signaling pathways allow plants to convey the

264 portance in dictating the formation of their intricate solid-state superstructures.

265 ities, including the gut microbiome, display intricate spatial organization(3-9).

266 lysis by high-resolution imaging defines the intricate spatial pattern of Las1L-Nol9 within the nucle

267 ing realization of multiscale materials with intricate spatially varying microstructures and thus, ma

268 ng species within bacterial colonies lead to intricate spatiotemporal dynamics, which can affect thei

269 ocesses are highly dynamic and controlled by intricate spatiotemporal mechanisms, we focus on aspects

270 Mammalian tissue development is an intricate, spatiotemporal process of self-organization t

271 The human inner ear has an intricate spiral shape often compared to shells of mollu

272 perties associated with memory, and exhibits intricate splicing patterns and post-translational modif

273 ble responses to sensory stimuli and exhibit intricate spontaneous activity even without external sen

274 An intricate stem cell niche boundary formed by finger-like

275 Our findings show how intricate structural features and acetylation patterns o

276 -free laboratory techniques to reproduce the intricate structure of natural bacterial habitats.

277 etrical and mechanical properties, realizing intricate structures and structural transformations that

278 Bottom-up construction of highly intricate structures from simple building blocks remains

279 Knots are intricate structures that cannot be unambiguously distin

280 ances in 3D bioprinting allow for generating intricate structures with dimensions relevant for human

281 two-photon polymerization allows creation of intricate structures.

282 dical fragment coupling reactions that unite intricate subunits have become an important class of tra

283 realized such as designing and implementing intricate synthetic gene circuits that perform complex s

284 ally efficient approach for simulation of an intricate system by integrating the deterministic and st

285 ation potential by moving an object along an intricate target path with a simple pressure input.

286 ling in receptor-mediated RhoA signaling via intricate temporal regulation.

287 nucleotide GAC RNA bound to L11 revealed the intricate tertiary fold of the RNA domain, with one mono

288 Yet each is now recognized as having intricate, though not fully elucidated, biological funct

289 -ray single-crystal (super)structures reveal intricate three-dimensional packing.

290 longstanding challenge to visualize how the intricate thylakoid network organizes these protein comp

291 presence of HAAs at a marginal level in the intricate tissue of food and their interactivity, an eff

292 m transitions from a simple epithelium to an intricate tissue that consists of distinct layers: the o

293 realization of the one-pot synthesis of the intricate topology.

294 o a fundamental lack of understanding of its intricate tuning mechanisms.

295 ngth is a physical measure of light, and the intricate understanding of its link to perceived colour

296 Unravelling this intricate web is a fundamental step in understanding the

297 evidence indicates that AD develops from an intricate web of biochemical and cellular processes that

298 suggest a motion model that is increasingly intricate when compared with the ubiquitous Hassenstein-

299 infer to be labyrinthine or otherwise highly intricate, with features smaller than 400 nm correspondi

300 on of oxide membranes, especially those with intricate wrinkle patterns, is challenging due to their