ライフサイエンスコーパス: introgress

1 genes from different wild tomato species are introgressed.

2 s great as 70% when other AltSB alleles were introgressed.

3 sequence-identical a1-sh2 interval had been introgressed.

4 into which mutant Dl and H alleles had been introgressed.

5 varieties were, on average, 3.8% (max 13.6%) introgressed.

6 salamanders from which the albino trait was introgressed.

7 al (12.5%), moderate (1.56%<X<12.5%) and non-introgressed (1.56%) according to the European taurine g

8 We introgressed 10% of the D. sechellia X chromosome into a

9 To our knowledge, this is the first study to introgress a morphological quantitative trait locus (QTL

10 rd the genetic dehorning of dairy cattle, we introgressed a bovine POLLED allele into horned bull fib

11 gh a series of interspecies crosses, we have introgressed a major locus affecting host preference fro

12 NZM2328.Lc1R27 (R27) was generated by introgressing a C57L/J region where Cgnz1 is located to

13 theoretically investigate the potential for introgressing a desired engineered gene into a pest popu

14 To test the feasibility of introgressing a high endoreduplication phenotype into a

15 ly it is being used in breeding programs for introgressing a new source of nematode resistance and to

16 Consistent with selection on the introgressed allele after the introduction of rodenticid

17 hly polygenic, with selection acting against introgressed alleles across most of the genome.

18 population size is thus increased and local introgressed alleles are rapidly outnumbered.

19 ion Africanized honeybees have low levels of introgressed alleles from resident European populations.

20 However, the same introgressed alleles increase in frequency and are favor

21 According to this model, archaic introgressed alleles were somehow distinct from those th

22 ation around mac-1 and the high diversity of introgressed alleles, although a localized change in bar

23 e attributed to systematic selection against introgressed alleles, consistent with strong selection a

24 ergence are associated with largely dominant introgressed alleles, have similar effects in the two se

25 odeling suggests that at least some of these introgressing alleles have contributed to the new adapta

26 y gene TLR1, as well as a unique Neanderthal introgressed alternative splicing variant in the gene HS

27 physiological and molecular consequences of introgressing an alien chromosome segment (7DL) from a w

28 ession backcross programs for simultaneously introgressing an allele and selecting for the desired ge

29 A congenic strain, S.R(chr9), constructed by introgressing an R chromosomal segment into the S backgr

30 The non-European taurine introgressed animals (n=425) show an unfluctuating zebu

31 Excluding European introgressed animals, low and nonsignificant genetic dif

32 Attempts to introgress apomixis from wild relatives into major crops

33 of genetic material ( approximately 2%) that introgressed approximately 35 kya from an archaic popula

34 When an introgressed archaic allele has a selective advantage, e

35 ure with archaic lineages, provided that the introgressed archaic allele has risen to high frequency

36 Here we demonstrate the presence of introgressed Asian haplotypes in European domestic pigs

37 the high-glucoraphanin hybrids possessed an introgressed B. villosa segment which contained a B. vil

38 that ray originated in this group, while ray introgressed back into H. elevatus much more recently.

39 incidence of male-to-female transfer in the introgressed background raises the possibility that pate

40 The ability to introgress beneficial genes under the control of specifi

41 Alleles that introgress between species can influence the evolutionar

42 ine whether mitochondrial DNA sequences have introgressed between the closely related African malaria

43 suggest that the size of the resistant Pi-ta introgressed block was at least 5.4 Mb in all elite resi

44 Some introgressed blocks are extremely large, consistent with

45 rmed to identify the region of PM resistance introgressed break points along with other traits inhere

46 ropean Americans in North America are barely introgressed by Amerindian genes in spite of known conta

47 When introgressed by backcross into the maize inbred line PH0

48 ot observe any differences between genotypes introgressed by chromosomal fragments of Robusta and non

49 Genetic lengths of introgressed chromosomal segments explain little of the

50 Susceptible (S) plants either contained no introgressed chromosome segment or a segment which was p

51 ribed genes, were simultaneously impacted by introgressed chromosomes 3S(l)#2 and 6S(l)#3, which acco

52 study, we report the genome-wide impacts of introgressed chromosomes derived from Ae. longissima on

53 ulans or D. sechellia); (ii) location of the introgressed D. mauritiana segment on the D. simulans th

54 In reciprocal chromosome 3 congenic mice, introgressed D2 alleles increased HSC numbers owing to e

55 In reciprocal chromosome 5 congenic mice, introgressed D2 alleles increased HSC numbers, whereas B

56 driven by modern Papuan ancestry as well as introgressed Denisovan and Neanderthal variation.

57 s of DNA that are inconsistent with a single introgressing Denisovan origin.

58 ve since produced at least 22 hybridized and introgressed descendants to date, of which at least 15 a

59 the bundling effect increases the purging of introgressed DNA by between 1.2-fold (in a baboon system

60 Congenic mice carrying introgressed DNA from DBA/2J on a C57BL/6J background we

61 telle, which contains a very small region of introgressed DNA, and the lack of recombinants suggest t

62 d modeling methods for implementing GS in an introgressed dura family derived from a Deli dura x Nige

63 moving one widespread (A) and one putatively introgressed (F) lineage increases these estimates to 65

64 le to speciation, mating preferences tend to introgress faster than trait alleles, causing sexual sel

65 ybridisation (GISH) was used to identify the introgressed fescue chromosome segment.

66 designated Lbw2 congenic) mice containing an introgressed fragment of New Zealand White (NZW) on chro

67 This plus the precise identity of the introgressed fragments between the donor and the recipie

68 stical methods developed to identify archaic introgressed fragments in the genome sequences of modern

69 odern humans and Neandertals has resulted in introgressed fragments of Neandertal DNA in the genomes

70 ds of modern humans and study the effects of introgressed fragments of Neandertal DNA on this phenoty

71 me based on the sizes of fertile and sterile introgressed fragments.

72 a series of near-isogenic lines with alleles introgressed from a wild relative of rice provides an op

73 Pto was first introgressed from a wild species of tomato into cultivat

74 ers, together with the associated mtDNA, has introgressed from A. encedana into A. encedon within the

75 lective sweep signatures appear to have been introgressed from A. lyrata This finding suggests that m

76 egions has acted on DNA that might have been introgressed from an extinct Sus species.

77 these populations, adaptive alleles may have introgressed from archaic populations into modern humans

78 ngenic strains possessing portions of Candq1 introgressed from B6 into Bc were generated and phenotyp

79 ssions, including an over-retained haplotype introgressed from bitternut hickory into pecan breeding

80 nt diabetes susceptibility region 10 (Idd10) introgressed from chromosome 3 of C57BL/6 (B6) and A/J m

81 Second chromosome regions were introgressed from D. mauritiana and D. sechellia into D.

82 mice where the telomeric region of chr.4 was introgressed from DBA/2 into C57BL/6 mice.

83 linked QTL in the 8L chromosome arm segment introgressed from Gaspe Flint (a Northern Flint open-pol

84 nome has cannabidiolic acid synthase (CBDAS) introgressed from hemp and lacks a complete sequence for

85 gnals and identify genomic regions that have introgressed from indicine into taurine cattle under pos

86 very few genomic segments that were commonly introgressed from low-chill Vaccinium species to the SHB

87 ergent selection in a region of chromosome 8 introgressed from maize and encompassing ZCN8, a major f

88 dissection of quantitative genetic variation introgressed from one source to another.

89 re mosaic-like, with approximately 25% being introgressed from other races.

90 We identified two genomic regions introgressed from red siskins into red factor canaries t

91 we demonstrate that the gene has likely been introgressed from the closely related species Neurospora

92 ineages and pinpoint large duplications that introgressed from the extinct Denisova lineage now found

93 Identification of haplotypes introgressed from the wild may also help in the identifi

94 assisted selection (MAS) programs to rapidly introgress G. barbadense phytochromes and/or HY5 gene (s

95 NA composition of the new genome because the introgressed genes are subject to the same mutational pr

96 ed by short divergence times or that contain introgressed genes from closely related species.

97 of those forms, suggesting selection against introgressed genes in the novel genetic background.

98 conflict, sperm competition, or epistasis of introgressed genes on novel backgrounds.

99 Further, functional analysis revealed introgressed genes that are essential to fitness, includ

100 ulation including two isolated but partially introgressed genetic groups, the females have an apparen

101 -term effects of purifying selection against introgressed genetic material.

102 ossed individuals with a small proportion of introgressed genome.

103 We report on a polymorphic introgressed genomic region in European M. m. domesticus

104 This finding suggests that introgressed genomic regions harbor both fitness-enhanci

105 hough demonstrating the adaptive function of introgressed genomic regions remains difficult.

106 Vkorc1, in addition to other newly detected introgressed genomic regions.

107 length distribution and sharing patterns of introgressed genomic tracts across the samples, we infer

108 original lines but heavily dependent on the introgressed genotype.

109 by chromosomal fragments of Robusta and non-introgressed genotypes.

110 Notably, we suggest that the Neandertal-introgressed haplotype likely reintroduced an ancestral

111 The Asian introgressed haplotypes are associated with regions harb

112 enrichment for RAs and depletion for NDAs on introgressed haplotypes with expression quantitative tra

113 obabilistic method called IBDmix to identify introgressed hominin sequences, which, unlike existing a

114 reviously that C57BL/6 congenic mice with an introgressed homozygous 70 cM (125.6 Mb) to 100 cM (179.

115 Disease protection, mostly offered by introgressed host-resistance genes, is often race-specif

116 from a cross involving N. sylvestris and an introgressed hybrid between N. tomentosiformis and N. ot

117 -waxy hybrids were agronomically superior to introgressed hybrids, producing on average 5.5 bushels p

118 ly influenced by the presence of a number of introgressed I. fulva alleles located throughout the gen

119 lowering to occur earlier in the season when introgressed I. fulva alleles were present, while the re

120 The superior allele/haplotype of this gene introgressed in desi and kabuli near-isogenic lines enha

121 0 T108A;I207L, originating in Denisovans and introgressed in modern humans throughout Oceania, and A2

122 a homozygous region of Drosophila mauritiana introgressed in the Drosophila simulans background.

123 enhanced by interaction with an additionally introgressed indica OsNRT1.1B allele.

124 chromosomal substitution strains derived by introgressing individual chromosomes from normotensive B

125 ptin receptor deficiency, respectively, were introgressed individually into both lines by repeated ba

126 ternative splicing variant at the adaptively introgressed innate immunity gene TLR1, as well as a uni

127 sophila sechellia or Drosophila simulans are introgressed into a common D. simulans genetic backgroun

128 segments of Drosophila mauritiana that were introgressed into a D. simulans background.

129 s of the D. mauritiana third chromosome were introgressed into a D. simulans genetic background and t

130 resistance to multiple fungal pathogens were introgressed into a disease-susceptible maize inbred lin

131 genetic material from wild tomato species is introgressed into a domesticated background, have been u

132 s from one species (Solanum habrochaites) co-introgressed into a heterospecific genetic background (S

133 genome represents Guatemalan source regions introgressed into a Mexican race background.

134 The mutant phenotype was introgressed into a standard Pisum sativum cv. Birte to

135 The Pst resistance of L. hirsutum was introgressed into a susceptible Lycopersicon esculentum

136 aim that transgenic DNA constructs have been introgressed into a traditional maize variety in Mexico,

137 The FR13A Sub1 locus was introgressed into a widely grown Asian rice cultivar usi

138 when Copenhagen (COP)-resistant alleles are introgressed into a Wistar Furth (WF)-susceptible genome

139 ts of nine teosinte alleles of tb1 that were introgressed into an isogenic maize inbred background.

140 e-determining chromosome from one species is introgressed into another one, and over-rides its previo

141 and the autonomous gene-drive components are introgressed into approximately 99.5% of the progeny fol

142 Resistance to root-knot nematode was introgressed into cultivated peanut Arachis hypogaea fro

143 In a region of 5% of the D. simulans genome introgressed into D. melanogaster, we discover at least

144 self causes a high level of infertility when introgressed into D. simulans.

145 3+), but can exhibit reduced expression when introgressed into different lines.

146 e provide evidence that wild barley alleles, introgressed into elite barley cultivars, can be utilize

147 t genetic material from European pigs likely introgressed into five Chinese breeds.

148 The dennis phenotype introgressed into Heliconius melpomene at about the same

149 Sr60 was successfully introgressed into hexaploid wheat, and we developed a di

150 nt portion of the local rice crop genome was introgressed into HR weedy rice, which was rare in histo

151 mans approximately 1.1 million years ago and introgressed into humans by approximately 37,000 years a

152 Japonica OsSGR alleles introgressed into indica-type cultivars in Korean rice f

153 o test this hypothesis, the mutant sbe1a was introgressed into lines containing either wx (lacking th

154 allele of M. spretus confers resistance when introgressed into M. m. domesticus.

155 ualizing alien chromatin from T. dactyloides introgressed into maize lines.

156 nds for >31 kb on chromosome 4 seems to have introgressed into modern Africans from a now-extinct tax

157 g, and floral scent, some of which have been introgressed into modern Anthurium cultivars.

158 g functionally distinctive alleles that have introgressed into modern Eurasian and Oceanian populatio

159 rge CNVs originating in archaic hominins and introgressed into modern humans have played an important

160 nome donor of hexaploid bread wheat, and was introgressed into modern wheat cultivars by breeding.

161 can fossils may represent a population which introgressed into Neandertals during the LMP.

162 wards the 19(th) and 20(th) centuries, Q was introgressed into non-European B. taurus and Bos indicus

163 Bcma-, Taci-, and Br3-null mutations were introgressed into NZM 2328 mice.

164 t morph originated on Kauai and subsequently introgressed into Oahu and (2) that flatwing originated

165 the proximal region of chromosome 10 (Chr10) introgressed into opposing backgrounds served as the beh

166 stance gene-like sequence NBSRps4/6 that was introgressed into soybean lines along with Rps4 or Rps6.

167 stock that colonized the Micos cave and also introgressed into the ancient Pachon cave population.

168 rulence molecules in the pathogen, have been introgressed into the cultivated potato from a wild spec

169 strain and containing the Cia10 interval was introgressed into the DA (arthritis-susceptible) backgro

170 gene subtype silenced at NOR2 is active when introgressed into the genome at NOR4.

171 rain is one in which an entire chromosome is introgressed into the isogenic background of another inb

172 most all of the edulis allelic diversity had introgressed into the M. galloprovincialis background in

173 ondrial DNA (mtDNA) from one strain has been introgressed into the nuclear background of another stra

174 and three S. brevidens markers may have been introgressed into the potato genome.

175 On average, 96% of each wild parent was introgressed into the Rasmusson background, and the popu

176 which the wild-derived Dl-H gene region was introgressed into the Sam chromosome 3 background; and a

177 ATa allele from a sequenced strain JEC20 was introgressed into the XL280 background to generate the c

178 cate such mutations, the dek phenotypes were introgressed into two inbred lines to take advantage of

179 effects of the mutation, each insertion was introgressed into two wild-type genetic backgrounds.

180 ity of the rebalancing was further tested by introgressing into the SP- line a green fluorescent prot

181 When the position of the gene to be introgressed is uncertain, for example because its posit

182 mplex regulatory network associated with the introgressed junctions mediated by PM resistance R prote

183 xhibited variation in the number and size of introgressed Kingwa loci.

184 Congenic strains were constructed by introgressing Lewis low-blood-pressure QTL alleles for c

185 Apparently these introgressed lines fail to suppress a normally silent me

186 We introgressed lines infected with Wolbachia, Cardinium or

187 of ahk double mutants using CycB1;1:GUS/ahk introgressed lines revealed contrasting differences in t

188 In less introgressed lines, double mutants can grow to maturity

189 Introgressed loci are underrepresented in low-recombinat

190 bridization, and understand the behaviour of introgressed loci in their new genomic background.

191 One introgressed locus contains a deletion in AHR that confe

192 Introgressing maize chromosome segments into the oat gen

193 We detected large introgressed Manihot glaziovii genome-segments in a coll

194 investigate near-isogenic barley lines with introgressed Mla6, Mla13, and Mla1 coiled-coil, nucleoti

195 er, we infer that Soay and Sarda sheep carry introgressed mouflon alleles involved in bitter taste pe

196 es revealed that none of the individuals had introgressed mtDNA from foreign species or subspecies of

197 nsequently, both divergent regions represent introgressed mtDNA resulting from intergeneric hybridiza

198 ) of the chipmunks we have sequenced exhibit introgressed mtDNA.

199 mbinant congenic strains (RCSs) developed by introgressing multiple NZO/HlLt chromosomal segments int

200 Several studies have suggested that introgressed Neandertal DNA was subjected to negative se

201 mixture nor Neanderthal introgression, since introgressed Neanderthal alleles are enriched in ADHD ri

202 haps reveal deep diversity, including entire introgressed Neanderthal centromeres and equally ancient

203 As a consequence, introgressed Neanderthal DNA survives scattered across t

204 ly to be tolerated by modern humans than are introgressed Neanderthal-derived alleles (NDAs) due to t

205 Developing quality protein maize (QPM) by introgressing o2 modifiers (Mo2s) into the o2 mutant ben

206 in which the DBA/2 allele of Chrna7 has been introgressed onto a C3H genetic background and, converse

207 mparing activity and sleep of mtDNA variants introgressed onto a common nuclear background in cytopla

208 onversely, the C3H allele of Chrna7 has been introgressed onto a DBA/2 genetic background.

209 this, resistant CAST/Ei (CAST) alleles were introgressed onto a susceptible C57BL/6J background to g

210 ongenic mice (which have an H2(b) MHC region introgressed onto an NOD non-MHC background).

211 When the transgene was introgressed onto four different genetic backgrounds, be

212 ngenic DR.(lyp/lyp) rats, where BBDP lyp was introgressed onto the diabetes-resistant BBDR background

213 taining the CYP4A genes from a Lewis rat was introgressed onto the SS genetic background.

214 For example, we found that an introgressed PDR5 was present exclusively in clinical or

215 nalysis of USVL531-PMR, USVL677-PMS and four introgressed PM resistant recombinant inbred lines (RIL,

216 The legal status of introgressed populations (native populations that are sl

217 ampling design in the study of structured or introgressed populations.

218 ns, like the X-chromosome inversions, do not introgress probably due to selective elimination in hybr

219 These results show that introgressed QTL can greatly improve broad-spectrum dise

220 m-OAc) were compared with Hs females with an introgressed quantitative trait locus from Heliothis vir

221 Two of these loci introgressed recently (18 to 34 generations ago) from At

222 enotyping microarray, we have identified the introgressed region as 16 Mb of chromosome 4, although a

223 Within the small introgressed region carried by RIL 46, a constitutively

224 Here, we show that a 114 kb introgressed region containing Hnrnph1 and Rufy1 was suf

225 Mapping of the introgressed region indicated that 92% of linkage group

226 Interestingly, a second introgressed region required for red feathers resides wi

227 Expression analysis of the introgressed region that is syntenic to human HSA4q21, a

228 ackground and found that males carrying this introgressed region were consistently fertile; in contra

229 cessions, we focus on identifying putatively introgressed regions (pIRs) between species.

230 The introgressed regions are enriched in genes involved in n

231 We used these methods to map the introgressed regions in an iron-inefficient soybean NIL

232 hese regions is similar to that observed for introgressed regions in Europeans.

233 entify and genetically map these defects, we introgressed regions of the Drosophila sechellia genome

234 entially expressed genes were located in the introgressed regions on chromosomes 1 and 3, validating

235 al traits consistent with the effects of the introgressed regions where they are located and that thu

236 and P. theophrasti, sharing of haplotypes in introgressed regions, and a population model that incorp

237 ding sequence than expected by chance in the introgressed regions, suggesting that natural selection

238 d recommendations for inferring selection on introgressed regions.

239 his hypothesis, we resurrected the ancestral introgressed reticulocyte-binding protein homologue 5 (R

240 mouse strains, each with on average a 23-cM introgressed segment (range 8 to 58 cM).

241 s of individual loci, since each interval or introgressed segment may contain multiple QTL.

242 monstrate a BP difference but with a reduced introgressed segment of 3Mb.

243 rain from the SHR.WKY-Sa animals carrying an introgressed segment of 4.3Mb, contains BP1.

244 t (R) plants in two BC3 lines all carried an introgressed segment on a single chromosome, which in on

245 mbinant lines, with a variable length of the introgressed segment, confirmed the presence of the two

246 ere positively correlated with the length of introgressed segments on the tomato map.

247 By comparing SNP genotypes within introgressed segments to the known genotypes of the dono

248 sex-ratio distortion that was discovered by introgressing segments of the genome of Drosophila mauri

249 Genome comparisons revealed an introgressed sequence in the ancestor of P. falciparum c

250 cally modern humans, we analyzed patterns of introgressed sequence in whole-genome data of 379 Europe

251 iduals, recovering more than 15 gigabases of introgressed sequence that spans ~20% of the Neandertal

252 Although genome-scale maps of introgressed sequences have been constructed [3-6], cons

253 y remains across modern Eurasian genomes and introgressed sequences influence diverse phenotypes.

254 Here, we demonstrate that introgressed sequences reintroduced thousands of ancestr

255 s were then conducted to further explore the introgressed signal within our dataset.

256 ic analysis of 122 Saccharomyces hybrids and introgressed strains.

257 g experiment, a chromosome segment should be introgressed that is likely to include the allele of int

258 nteractions, we used interspecific mating to introgress the bwD allele from D. melanogaster into D. s

259 ed into a natural population to successfully introgress the desired gene.

260 s generated by a series of 11 backcrosses to introgress the MAT locus from a nonoutbreak strain into

261 encountered by plant breeders when trying to introgress the polygene-based resistance.

262 used to bypass F1 hybrid male sterility and introgress the sex distorter I-PpoI into the A. arabiens

263 st major crops rely on classical breeding to introgress the transgene from a laboratory variety to th

264 We introgressed the mitochondria and some passenger loci fr

265 each construct being the most efficient for introgressing the desired gene.

266 nd to generate gene-drive systems capable of introgressing the genes throughout wild vector populatio

267 Introgressing the genome of Nasonia giraulti into the in

268 veloped congenic strains for Chr 2 and 10 by introgressing the low BP QTL alleles into the Dahl salt-

269 Introgressing the ob allele into BTBR revealed large dif

270 Recently, by introgressing the OLETF-derived, CCK1R-null gene onto a

271 A congenic strain introgressing the R low-blood-pressure QTL allele on chr

272 Introgressing the same locus from the other species in t

273 n2, we generated a double-congenic strain by introgressing these loci from glomerulonephritis-resista

274 Penguin species have introgressed throughout much of their evolutionary histo

275 n while DNA from either DBA/2 or CAST/Ei was introgressed to form the congenic region.

276 ments employ mosquito strains that have been introgressed to provide genetically similar strains that

277 nsgenic lines (DC1) having PcINO1 and PcIMT1 introgressed together, were less efficient in such respe

278 Second, several of the inferred introgressed tracts contain genes that are likely to con

279 The introgressed tracts have been fixed within lineages, sug

280 Third, introgressed tracts might contain driver genes that dete

281 sirable, linked traits that often complicate introgressing traits into crops from wild relatives.

282 Although the effects of introgressed trans-regulatory alleles are similar in mal

283 Here we report the presence of introgressed transgenic DNA constructs in native maize l

284 purge unfavorable alleles from cultivars or introgress valuable alleles from exotics.

285 diversity in their germplasm collections, to introgress valuable traits from new sources, and to iden

286 ontaining 4303 unique genetic variants where introgressed variants are highly likely to have a phenot

287 stricted runaway duplications and putatively introgressed variants from archaic hominins.

288 Adaptively introgressed variants were enriched for moderate-effect

289 hile RAs have activity levels similar to non-introgressed variants.

290 selected target, characteristic of sweeps of introgressed variation and consistent with diversity pat

291 Despite extensive removal of introgressed variation by recurrent selection for domest

292 omesticated soybeans was widespread and that introgressed variation in both wild and domesticated soy

293 polymorphisms present in extant populations introgressed via relatively recent interbreeding with ho

294 een wdw and other QTL are also identified by introgressing wdw from N. vitripennis into N. giraulti.

295 dern varieties, including lines historically introgressed with C. canephora, highlights their breedin

296 lines, which are exotic lines that have been introgressed with dwarfing quantitative trait loci (QTL)

297 However, there was no evidence that it is introgressed with germplasm from two other alien Ligustr

298 ) populations, with some likely to have been introgressed with O. mossambicus, is a key resource for

299 000-year-old fossil form from the same area, introgressed with the modern form now characteristic of

300 Using three generations of crosses, we introgressed X chromosomes from each species onto differ