ライフサイエンスコーパス: ionomycin

1 including the secretion of leucocidins (e.g. ionomycin).

2 (phorbol 12-myristate 13-acetate [PMA] plus ionomycin).

3 n with ouabain versus Ca(2+) modulation with ionomycin.

4 -CD28 or phorbol-12-myristate-13-acetate and ionomycin.

5 f neutrophil protection after treatment with ionomycin.

6 ion with phorbol 12-myristate 13-acetate and ionomycin.

7 3 + anti-CD28 monoclonal antibodies or PMA + ionomycin.

8 , or Ca(2+) mobilization by thapsigargin and ionomycin.

9 cells by provision of calcium signals using ionomycin.

10 pamycin/FRB/FKBP system or by treatment with ionomycin.

11 arkedly different from the rapid response to ionomycin.

12 ollowing stimulation with either anti-IgM or ionomycin.

13 ted with phorbol 12-myristate 13-acetate and ionomycin.

14 also by the pharmacological stimuli PMA and ionomycin.

15 of Nox5 in response to low concentrations of ionomycin.

16 increased activity at low concentrations of ionomycin.

17 anti-CD3 and anti-CD28 antibodies or PMA and ionomycin.

18 ished Mn ionophores, calcimycin (A23187) and ionomycin.

19 jority make IFN-gamma in response to PMA and ionomycin.

20 ulation with phorbol myristate acetate (PMA)/ionomycin.

21 tion and was greater than that observed with ionomycin.

22 osed to H(2)O(2) but not in cells exposed to ionomycin.

23 such as angiotensin-II and a Ca2+ ionophore, ionomycin.

24 n nonneuronal cells on Ca2+ entry induced by ionomycin.

25 w-derived cultured mast cells in response to ionomycin.

26 oubled the amplitude of transients evoked by ionomycin.

27 overload (1.6 mM) after permeabilization by ionomycin.

28 e cells were activated by phorbol ester plus ionomycin.

29 inhibitors prevented E-cad(100) induction by ionomycin.

30 t were absent after exposure to either FN or ionomycin.

31 tivated protein kinase (AMPK) in response to ionomycin.

32 ol 12-myristate 13-acetate (PMA), but not by ionomycin.

33 n stimulation with ionophores, nigericin, or ionomycin.

34 liminated L. amazonensis when incubated with ionomycin.

35 and without phorbol 12-myristate 13-acetate/ionomycin.

36 e antibacterial peptide LL-37 in response to ionomycin.

37 onses to phorbol 12-myristate 13-acetate and ionomycin.

38 in vitro mitogenic stimulation with PMA and ionomycin.

39 and actinomycin D and with necrosis inducer ionomycin.

40 ion with phorbol 12-myristate 13-acetate and ionomycin.

41 oss-linking antibodies or phorbol ester plus ionomycin.

42 ulation with epidermal growth factor (EGF) + ionomycin.

43 induces Treg proliferation in the absence of ionomycin.

44 on with phorbol 12-myristate 13-acetate plus ionomycin.

45 lated by phorbol 12-myristate 13-acetate and ionomycin.

46 ocation was rescued by the Ca(2+) ionophore, ionomycin.

47 active calcineurin or the calcium ionophore ionomycin.

48 mal concentration of the strong secretagogue ionomycin (1 microM), for which there was a delay betwee

49 res, stimulation (S2) of the same cells with ionomycin (10 microM), in the absence of extracellular c

50 After stimulation with the calcium ionophore ionomycin, 2-AG levels in MGL-silenced cells were compar

51 inhibitor), histamine (cAMP activator), and ionomycin (a Ca(2+) ionophore) to tissue-engineered cons

52 es revealed that basal and evoked IK(ATP) by ionomycin, a Ca(2+) ionophore, is activated by CaMKII.

53 yristate 13-acetate (PMA) to activate PKC or ionomycin, a Ca(2+) ionophore.

54 Moreover, Ionomycin, a Ca(2+)-dependent pathway activator, stimula

55 Ionomycin, a calcium ionophore, causes rapid mitochondri

56 Stimulation of mouse astrocytes with ionomycin, a calcium ionophore, enhanced the production

57 Stimulation of VSM cells with ionomycin, a calcium ionophore, resulted in activation o

58 As with monensin and ionomycin, a minor fraction of activity may be electroge

59 CD300f also binds PMA/ionomycin-activated splenocytes and Ag-stimulated T cell

60 th lipopolysaccharide, phorbol myristate and ionomycin (agonists).

61 to the SUMO-1 bodies, whereas treatment with ionomycin alone induced nuclear translocation of NFAT1 b

62 In contrast, treatment with PMA or ionomycin alone induces chromatin remodeling at far fewe

63 We report that ionomycin alone induces IL-4 and IFN-gamma, but not IL-2

64 whereas anergic transcription stimulated by ionomycin alone may occur without recruitment into the S

65 ation with PMA and ionomycin, but not PMA or ionomycin alone, induces cyclin D2 expression and cell-c

66 Ionomycin also activates CaMKIV, which, together with p3

67 The calcium ionophore ionomycin also induced a rapid hyperpolarization.

68 The Ca2+ ionophore ionomycin also inhibited bTREK-1 currents through channe

69 diation, H(2)O(2), and the Ca(2+) ionophore, ionomycin, also stimulated NOS activity, and this was as

70 Treatment of Wnt4(-/-) kidneys with Ionomycin, an activator of the pathway, partially rescue

71 astly, the activation of AMPK in response to ionomycin and 2-deoxyglucose is not impaired in LKB1(-/-

72 maximum depletion produced by the ionophores ionomycin and A23187.

73 rescued SOCE in response to thapsigargin and ionomycin and abrogated IFN-alpha/beta-induced apoptosis

74 H2O2 generated by DeltakatG likely oxidizes ionomycin and alters its ability to transport Ca(2+).

75 Using phorbol myristate acetate (PMA)/ionomycin and anti-CD3 activation of CD4(+)CD25(-) cells

76 their PBMCs by phorbol-myristate acetate and ionomycin and both IFN-gamma and IL-4 deficiencies in V(

77 on with both phorbol 12-myristate 13-acetate/ionomycin and CMV-peptide-loaded antigen-presenting cell

78 studied in mouse keratinocytes treated with ionomycin and during the wound-healing process.

79 The calcium mobilizing agents ionomycin and glutamate stimulate endogenous HO2 activit

80 nal activation with anti-CD3 or with PMA and ionomycin and in both C57BL/6 and BALB/c mice.

81 go autophosphorylation in cells treated with ionomycin and is likely also targeted by PKA.

82 mRNA and protein after stimulation with PMA/ionomycin and latency-reversing agents (LRAs).

83 induced in unfertilized mouse eggs by using ionomycin and manipulating extracellular calcium.

84 Ionomycin and phorbol 12-myristate 13 acetate (PMA) are

85 enhanced IFN-gamma expression in response to ionomycin and phorbol 12-myristate 13-acetate and weakly

86 rthermore, we found that treatment with both ionomycin and phorbol 12-myristate 13-acetate ensured ef

87 Ionomycin and phorbol 12-myristate 13-acetate further in

88 l activity of NFAT1 upon co-stimulation with ionomycin and phorbol 12-myristate 13-acetate, whereas a

89 Using protease inhibitors, ionomycin and phorbol myristate acetate stimulation, sma

90 Ag-free protocol that included bryostatin 1/ionomycin and sequential common gamma-chain cytokines (I

91 this, BMP2 gene expression was increased by ionomycin and suppressed by the calcineurin inhibitor, c

92 Ionomycin and thapsigargin increased intracellular Ca2+

93 The Ca(2+) ionophore ionomycin and the excitotoxin glutamate induced producti

94 2-myristate 13-acetate and calcium ionophore ionomycin and was blocked by the NFAT antagonist cyclosp

95 q-coupled [Ca(2+)]i increase was mimicked by ionomycin and was not affected by inhibition of protein

96 In this study, using the calcium ionophore ionomycin and/or PMA on Jurkat T cells, we show that the

97 istinct consequences on caspase-independent (ionomycin) and -dependent (ABT-263) cell death.

98 with different stimuli, including Con A, PMA/ionomycin, and allogeneic spleen cells.

99 ty to mobilize calcium upon stimulation with ionomycin, and BCR-induced calcium mobilization from int

100 dence on store depletion by thapsigargin and ionomycin, and differential sensitivity to inhibition by

101 , including purinergic receptor stimulation, ionomycin, and increases in cell volume, each activated

102 +) pools remained sensitive to thapsigargin, ionomycin, and inositol trisphosphate.

103 activity that is activated by phorbol ester, ionomycin, and okadaic acid.

104 l responses to phorbol myristate acetate and ionomycin, and possessed decreased levels of CD3zeta.

105 on of Pyk2 and ERK than the Ca(2+) ionophore ionomycin, and the effects of PMA and Ang II were abolis

106 2-myristate 13-acetate, the Ca(2+) ionophore ionomycin, and the serine/threonine phosphatase inhibito

107 more vulnerable to the cytotoxic effects of ionomycin- and 2,5-di-(t-butyl)-1,4-hydroquinone-induced

108 reover, anthrax LT specifically inhibits PMA/ionomycin- and anti-CD3-induced IL-2 production in Jurka

109 ntly enhance phorbol 12-myristate 13-acetate/ionomycin- and anti-CD3-stimulated lymphocyte apoptosis.

110 by dimethylsphingosine blocks thapsigargin-, ionomycin-, and platelet-activating factor-mediated SOCE

111 ing CD8 + PD-1 + T cells stimulated with PMA/ionomycin as well as with HLA-A*24:02 CMV peptide was da

112 splayed limited Ca(2+) influx in response to ionomycin, as a result of ionophore H2O2 sensitivity.

113 Conversely, thapsigargin and ionomycin attenuated the BAPTA-AM effects and promoted N

114 eased degranulation response to K562 and PMA/ionomycin but lower capacity to respond to human CMV-inf

115 attenuated latency reversal by phorbol ester+ionomycin but not by anti-CD3+anti-CD28.

116 nd A549 cells, mannitol, 2-deoxyglucose, and ionomycin, but not 5-aminoimidazole-4-carboxamide-1-beta

117 ing (G0) B cells, costimulation with PMA and ionomycin, but not PMA or ionomycin alone, induces cycli

118 erent localized [Ca2+] upon stimulation with ionomycin, but rather differences in phosphorylation sta

119 of Pasteurella multocida toxin by 2-fold and ionomycin by 3-fold.

120 function was examined by treating cells with ionomycin (calcium influx), thapsgargin (endoplasmic ret

121 Furthermore, ionomycin (calcium ionophore) and TPA augmented the enha

122 PMA and ionomycin cause T cell cytokine production.

123 Exposure to ionomycin caused an increase in I sc 2-fold greater than

124 H(2)O(2) and ionomycin caused cell death in a dose-dependent manner,

125 Higher ionomycin concentrations induce a stochastic failure of

126 ar Ca(2+) inhibited both A(2B) receptor- and ionomycin-dependent IL-4 secretion.

127 Topical lingual application of ionomycin did not affect the phasic part of the CT respo

128 Ca(2+) mobilization by ionomycin did not permit dGal-1 to mobilize PS, indicati

129 imulation with phorbol myristate acetate and ionomycin did not restore the production of IFN-gamma.

130 ion of phorbol 12-myristate 13-acetate (PMA)/ionomycin-driven activation of a luciferase reporter con

131 in response to phorbol myristate acetate and ionomycin, duodenal LPLs from ethanol-drinking animals g

132 In response to ionomycin, EGFP-cPLA(2)zeta translocated to ruffles and

133 Moreover, complement and EGF + ionomycin enhanced phosphorylation of Ser-511.

134 e channels, in HEK293 cells expressing CLCAs ionomycin-evoked increases in intracellular calcium stim

135 Although agonist or ionomycin exposure can raise bulk [Ca(2+)](i) to levels

136 contrast to wild type cells, treatment with ionomycin failed to increase GlcAT-I promoter activity i

137 n ex vivo with phorbol myristate acetate and ionomycin for 5 hours.

138 r stimulation with phorbol myristate acetate-ionomycin, high gamma interferon and low IL-4 levels wer

139 ed with phorbol 12-myristate 13-acetate plus ionomycin, IL-25 plus IL-33 (IL-25/IL-33), or a mixture

140 onse to phorbol 12-myristate 13-acetate plus ionomycin, IL-25/IL-33, or a mixture of TLR ligands.

141 e RGC-5 following 24 h of exposure to 250 nM ionomycin (IMN) or 300 units/ml interferon-gamma (IFN-ga

142 lar Ca2+ to saturating levels with 10 microM ionomycin in the presence of 10 mM extracellular Ca2+ eq

143 Cells were stimulated with phorbol ester and ionomycin in the presence of brefeldin A and stained for

144 A suboptimal concentration of ionomycin in the presence of PMA fully activates Tgfb1(-

145 rtantly, activation of the RCAN1 promoter by ionomycin, in control and FHL2 knockdown cells, was abol

146 In the presence of cAMP, ionomycin increased sensory adaptation to HCl, CO(2), an

147 s expressing TF(C186S/C209S) with HgCl(2) or ionomycin increased the cell-surface TF activity to the

148 The calcium ionophore, ionomycin, induced chondrogenesis through activation of

149 mutation displayed increased area under the ionomycin-induced [Ca(2+)](i) versus time curve (AI) com

150 also partially resistant to calcineurin- or ionomycin-induced apoptosis.

151 d mode of NCX, evaluated in experiments with ionomycin-induced Ca(2+) influx into neurons, was strong

152 Ionomycin-induced Ca(2+) influx promoted p-Akt, an effec

153 One and two ionomycin-induced Ca(2+) transients resulted in 39 and 4

154 itor of Mek1,2, had no appreciable effect on ionomycin-induced calpain activation.

155 However, it had minimal effect on PMA/ionomycin-induced CD69 up-regulation in Jurkat cells, on

156 nd rescued Nrf2-/- neurons from rotenone- or ionomycin-induced cell death.

157 II activity with KN93 abolished thrombin- or ionomycin-induced CREB phosphorylation on Ser(142) witho

158 Ionomycin-induced cytokine production requires NFAT, p38

159 neurons, E3 neurons were less susceptible to ionomycin-induced cytotoxicity.

160 mast cells eliminates both IgE-dependent and ionomycin-induced degranulation and causes a significant

161 psilonRI-mediated degranulation, but not PMA/ionomycin-induced degranulation, as shown by beta-hexosa

162 e formin INF2 reduces both un-stimulated and ionomycin-induced Drp1 accumulation and mitochondrial fi

163 tory to phorbol 12-myristate 13-acetate plus ionomycin-induced ERK1/2 phosphorylation (referred to as

164 vity in an assay measuring inhibition of PMA/ionomycin-induced human PBMC proliferation.

165 Both the basal and ionomycin-induced I sc were inhibited by basolateral Ba

166 ARTS-1 expression also enhances ionomycin-induced IL-1RII shedding.

167 ng mechanism while simultaneously monitoring ionomycin-induced intracellular Ca(2+) elevations with f

168 G protein-coupled receptor activation, or by ionomycin-induced intracellular calcium release.

169 Phorbol-12-myristate-13-acetate/ionomycin-induced MAPK signaling was measured by whole-b

170 During ionomycin-induced mitochondrial fission, F-actin clouds

171 At the opposite, ionomycin-induced NFAT activity allows survival of nonre

172 chelators (BAPTA, EGTA) inhibited basal and ionomycin-induced NO production, they failed to inhibit

173 Knocking down ASK1 inhibits ionomycin-induced p38 phosphorylation and IL-4 productio

174 ARC down-regulation was further confirmed as ionomycin-induced PARC down-regulation in both chemosens

175 vD4-treated mice were less susceptible to an ionomycin-induced release of neutrophil extracellular tr

176 d found that phorbol 12-myristate 13-acetate/ionomycin-induced transcription was augmented by IL-2 tr

177 horing protein (AKAP) 79 and interferes with ionomycin-induced translocation of conventional PKC to t

178 timulation of Tgfb1(-/-) T cells by PMA plus ionomycin induces IL-2 production and mitogenic response

179 Ionomycin induces p38 phosphorylation through a calcium-

180 uorophores following activation with calcium-ionomycin, ionomycin, or hPLCzeta cRNA microinjection.

181 psigargin, or phorbol myristate acetate plus ionomycin, leading to persistent NFAT (nuclear factor of

182 Treatment of MCF-7 cells with ionomycin led to increased accumulation of beta-cat(75)

183 isplay a concentration-dependent response to ionomycin: low concentrations mimic nigericin by hyperpo

184 Ouabain and ionomycin may be useful pharmacologic agents for increas

185 hancement of phorbol 12-myristate 13-acetate/ionomycin-mediated activation signals.

186 m sequestration since neither treatment with ionomycin nor endothelin-1, both of which elevated the i

187 , stimulating internal Ca(2+) by exposure to ionomycin not only caused greater stimulation of K(+) ((

188 tinin-4 potentiates the inhibitory effect of ionomycin on NHE3 activity by accelerating the oligomeri

189 mice following treatment with either PMA and ionomycin or anti-CD3 was markedly inhibited.

190 y human T cells activated with phorbol ester/ionomycin or antibodies against CD3/CD28.

191 The Ca2+-dependent changes in CBF induced by ionomycin or ATP were not affected by KT5823.

192 hyperpolarization; however, Ca(2+) influx by ionomycin or Ca(2+) release from intracellular stores by

193 In the presence of rCIL-2, PMA plus ionomycin or Con A stimulated CD4(+)CD25(+) cell prolife

194 t by mitogen phorbol 12-myristate 13-acetate/ionomycin or cytokine tumor necrosis factor alpha, two w

195 eatment with phorbol 12-myristate 13-acetate/ionomycin or lipopolysaccharide, and unique sensitivity

196 Whole-cell currents activated by ionomycin or methacholine were anion-selective and showe

197 vity of nigericin for Pb(2+) exceeds that of ionomycin or monensin and arises, at least in part, from

198 ow sodium conditions, and in the presence of ionomycin or monensin, which enhanced pneumococcal sensi

199 ulated proliferation, which was corrected by ionomycin or reconstitution of Bid, particularly an ER-t

200 gglutinin P or with Ca(2+)-mobilizing agents ionomycin or thapsigargin induced accumulation of FM1-43

201 f TRP-3/SPE-41 in spe-38 mutant spermatozoa, ionomycin or thapsigargin induced influx of Ca(2+) remai

202 lation with either phorbol myristate acetate/ionomycin or the Vdelta2 gammadelta T-cell receptor agon

203 ntrast in human dermal fibroblasts, TPA plus ionomycin or TPA did not significantly alter the proport

204 00) was generated by treatment of cells with ionomycin or TPA.

205 stimulating bypassing surface proteins (PMA:ionomycin) or through the TCR (e.g., viral Ags).

206 lular calcium by the P2-purinergic receptor, ionomycin, or a direct activator of phospholipase C, ind

207 n A (Con A), phorbol myristate acetate (PMA)/ionomycin, or anti-CD3/anti-CD28 before comparing the pr

208 mounts of TNFalpha in response to Con A, PMA/ionomycin, or anti-CD3/anti-CD28.

209 -linking or by phorbol-myristate acetate and ionomycin, or by phytohemagglutinin.

210 following activation with calcium-ionomycin, ionomycin, or hPLCzeta cRNA microinjection.

211 Stimulation with CD3/CD28, PMA/ionomycin, or latency reversing agents prostratin and SA

212 stimulation with platelet activating factor, ionomycin, or phorbol 12-myristate 13-acetate was signif

213 Downregulation was not induced by PMA-ionomycin, or prevented by PI3K inhibition, implicating

214 (LPS), phorbol myristate acetate (PMA) plus ionomycin, or purified protein derivative (PPD) was stud

215 ts showed that 20 microM ouabain, 0.3 microM ionomycin, or their combination increased the tensile mo

216 as degraded after 10 min exposure to PMA and ionomycin, or TNF and was maximally degraded by 30 min.

217 additional 379% after short-term exposure to ionomycin (P < 0.05).

218 induced in the Th2 clone D10 after PMA plus ionomycin (P/I) stimulation; however we found that the I

219 nduced with chemical activators of shedding (ionomycin, phorbol 12-myristate 13-acetate, and 4-aminop

220 ed (U), with phorbol 12-myristate 13-acetate/ionomycin (PI) or lipopolysaccharide (LPS), and stained

221 ints by the intra-articular Ca(2+) ionophore ionomycin, prostaglandin E(2), cAMP-raising agents, seri

222 terleukin-2, phorbol 12-myristate 13-acetate/ionomycin, prostratin, panobinostat, or romidepsin.

223 Following ex vivo stimulation with PMA/Ionomycin, PSC patients showed significantly increased n

224 o stimulation with phorbol myristate acetate/ionomycin, PSC patients showed significantly increased n

225 sue with phorbol-12-myristate-13-acetate and ionomycin, recapitulating CAVD microenvironment, resulte

226 lin, or stimulating calmodulin activity with ionomycin, reduces Smad2 levels.

227 1 in N2a cells reduced the Ca(2+) content of ionomycin-releasable intracellular stores and decreased

228 signalosome and can be activated by PMA and ionomycin, respectively.

229 -21 cells with phorbol myristate acetate and ionomycin resulted in a small increase in the amount of

230 Treatment with the calcium ionophore ionomycin resulted in increased GlcAT-I expression, wher

231 es with phorbol 12-myristate 13-acetate plus ionomycin results in transcriptional repression of TdT e

232 Exposure to basolateral ionomycin, reversibly increased TRC Ca(2+), resting pH(i

233 PMA and ionomycin significantly increased the activation of MAPK

234 Treatment with PMA and ionomycin significantly prevented the decrease in IL-17

235 Treatment of intact cells with ionomycin stimulated a rapid increase in FAK phosphoryla

236 ted CD4+ T cells and immune responses of PMA/ionomycin stimulated CD4+ T cells by FACS analysis purif

237 Phorbol 12-myristate 13-acetate and ionomycin stimulated ectodomain shedding of meprin beta

238 -O-tetradecanoylphorbol 13-acetate (PMA) and Ionomycin stimulated Jurkat cells.

239 ously demonstrated that ATP is released from ionomycin-stimulated airway epithelial goblet cells coor

240 Furthermore, 2-deoxyglucose- and ionomycin-stimulated AMPK activity, alphaThr-172 phospho

241 roduction in phorbol 12-myristate 13-acetate/ionomycin-stimulated human CD4+ T cells isolated from he

242 ion of phorbol 12-myristate 13-acetate (PMA)/ionomycin-stimulated human peripheral blood mononuclear

243 sal and phorbol 12-myristate 13-acetate plus ionomycin-stimulated interferon-gamma, IL-4, and tumor n

244 Complement- and EGF + ionomycin-stimulated iPLA(2)gamma activity was attenuate

245 Fibrinogen clustered on the surface of ionomycin-stimulated neutrophils to delay NETosis; and b

246 ne (PP2) abrogates 17beta-estradiol- but not ionomycin-stimulated NO release.

247 he sheddase responsible for constitutive and ionomycin-stimulated processing of the PDGFRbeta.

248 and were the primary source for histamine or ionomycin-stimulated secretion of these molecules.

249 utive, phorbol 12-myristate 13-acetate-, and ionomycin-stimulated shedding of meprin beta and meprin

250 e ADAM10 substrate betacellulin, whereas the ionomycin-stimulated shedding of the ADAM17 substrates C

251 ACScan flow cytometry, the proportion of PMA/ionomycin-stimulated T cells expressing cytokines ex viv

252 Both naive and PMA plus ionomycin-stimulated thymic CD4(+)CD25(+) cells suppress

253 ing cell phorbol 12-myristate 13-acetate and ionomycin stimulation and calcineurin activation.

254 - mice respond to anti-CD3/anti-CD28 and PMA/ionomycin stimulation and produce IL-2 similar to WT.

255 conventional CD4+CD25- T cells following PMA/ionomycin stimulation demonstrated no differences in ind

256 LPS, PMA, plus ionomycin stimulation in vitro for 5 h induced B10 cells

257 higher [Ca2+] in unstimulated cells but upon ionomycin stimulation, the probes experienced equal amou

258 B cells to express IL-10 following PMA plus ionomycin stimulation.

259 peptide-coated cells, CD3/CD28 Abs, and PMA/ionomycin stimulation.

260 rimary human CD14(+) monocytes after PMA and ionomycin stimulation.

261 to phorbol 12-myristate 13-acetate (PMA) and ionomycin stimulation.

262 Ionomycin studies indicated that intracellular Ca2+ stor

263 by global Ca(2+) signals induced by IP(3) or ionomycin, suggesting that critical, local Ca(2+) nanodo

264 Ionomycin, thapsigargin, and dialysis of the cell with i

265 Abeta secretion induced by thapsigargin and ionomycin (that elevate intracellular calcium concentrat

266 ulated by compounds (forskolin, epinephrine, ionomycin) that raise cellular cAMP or calcium levels.

267 in alpha-latrotoxin, or the Ca(2+)-ionophore ionomycin), the homo- and heteromultimerization of synap

268 aive animals stimulated with LPS or PMA plus ionomycin, the levels were significantly enhanced after

269 ide pathway, including the calcium ionophore ionomycin, the nitric oxide donor S-nitroso-N-acetylpeni

270 with cPLA2 and mutants were stimulated with ionomycin, the wild type and S505E translocated to the p

271 With stimulation by PMA/ionomycin, TNF-alpha, or H(2)O(2), PBMCs from ulcerative

272 during apical or basolateral application of ionomycin to increase [Ca(2+)]i near the apical or basol

273 vity was demonstrated by using the ionophore ionomycin to mimic sumatriptan action.

274 blocks the ability of the calcium ionophore ionomycin to promote neurite outgrowth.

275 ase in intact human red cells by introducing ionomycin to raise cytoplasmic Ca++, phosphatidylserine

276 This association requires ionomycin together with a phorbol ester, which also sugg

277 er 20 min of IL-4 (50 ng/ml), but not IL-13, ionomycin transients were decreased to 0.50 +/- 0.16 (S2

278 vation under phorbol 12-myristate 13-acetate/ionomycin treatment conditions.

279 Inhibition of Cn following ionomycin treatment did not block GlcAT-I and tauT, a To

280 imulation or phorbol 12-myristate 13-acetate/ionomycin treatment enhances P2 promoter activity.

281 PMA/Ionomycin treatment of DOCK8-deficient NK cells rescued

282 rial [Ca(2+)] and cell death after prolonged ionomycin treatment, as a model of Ca(2+) overload, were

283 Moreover, following ionomycin treatment, fibroblasts from CnAalpha and CnAbe

284 Elevation of intracellular calcium by ionomycin treatment, or activation of acetylcholine rece

285 into fragments when the ER was fragmented by ionomycin treatment.

286 subset of cells also secreted IL-4 with PMA/ionomycin treatment.

287 elevation of cytoplasmic Ca(2+) levels with ionomycin upregulated FN-binding activity, demonstrating

288 l activity was decreased, and sensitivity to ionomycin was abolished.

289 g induced by TCR cross-linking, IL-2, or PMA/ionomycin was found to be blunted within all T cell subp

290 However, calcium mobilization alone by ionomycin was insufficient for IRF3 phosphorylation.

291 horbol 12-myristate 13-acetate combined with ionomycin, was inhibited.

292 nd Jurkat CD4(+) T cells stimulated with PMA/ionomycin, we demonstrate activation (phosphorylation) o

293 imulation with phorbol myristate acetate and ionomycin, we examined gamma interferon (IFN-gamma), IL-

294 ed necrosis mediated by the Ca(2+) ionophore ionomycin, whereas apoptosis mediated by the Bcl-2 inhib

295 ce of extracellular Ca2 and 2) the effect of ionomycin, which could not take Ca2+ out of acidic organ

296 n in vitro Conversely, the calcium ionophore ionomycin, which disrupts calcium gradients, blocks AAV

297 f-function of Calfacilitin can be rescued by ionomycin, which increases intracellular calcium.

298 s, phorbol 12-myristate 13-acetate (PMA) and ionomycin, which mobilize elements of the phospholipase

299 th phorbol 12-myristate 13-acetate (PMA) and ionomycin, which signal via protein kinase C (PKC) and c

300 were first stimulated in vitro with PMA and ionomycin, which yielded IFN-gamma in 25% of cells.