ライフサイエンスコーパス: joint effect

1 nd that the combination of both results in a joint effect.

2 stGWA-GE, to test for GEI effect and G + GxE joint effect.

3 tify the optimal tree model representing the joint effect.

4 , but at a cost of flexibility in models for joint effects.

5 exposures and now flexibly assess models for joint effects.

6 s their concurrent nature and evaluate their joint effects.

7 two inputs by measuring their individual and joint effects.

8 re at higher risk of asthma when considering joint effects.

9 in plants, but few studies have tested their joint effects.

10 ip code level, certain areas observed strong joint effects.

11 dditive interaction when considering overall joint effects.

12 burden of these exposures and predictors of joint effects.

13 teraction (RERI) were quantified to consider joint effects.

14 ts: marginal only, main and interaction, and joint effects.

15 as nonlinear, interactive, correlative, and joint effects.

16 t was additive (complementary) for peak VO2 (joint effect, 2.5 mL/kg/min).

17 , and implicated its interaction with ERCC8 (joint effect: 3.03 <= OR <= 5.31, 0.01 <= p(interaction)

18 pollutants within a zip code drove stronger joint effects; a higher percentage of commuters who walk

19 In assessing joint effects, addition of CRP to standard lipid screeni

20 Moreover, we observed a joint effect among the TM6SF2 rs58542926, the PNPLA3 rs7

21 otype frequency, effect sizes, and models of joint effects among genetic variants on lifetime risk es

22 The joint effect analyses indicated that the lowest risk was

23 In joint-effects analyses, compared with women with high di

24 Joint effect analysis indicated that individuals with bo

25 om 2.3 for 1 to 10.0 for 4 risk alleles in a joint effect analysis of Age-Related Maculopathy Suscept

26 on assumptions of additive or multiplicative joint effects and breast cancer incidence rates.

27 plaining associations were investigated, and joint effects and interactions between conditions on hea

28 e models capable of both characterizing such joint effects and providing new insight into pathogenesi

29 versity might be adversely affected by their joint effects and where EWEs might facilitate the establ

30 s employed to identify the models with locus joint effects, and interaction was further verified by c

31 s, we show that the same isobole pattern and joint effects are generated by modeled combinations of f

32 Joint effects are notoriously hard to identify and chara

33 smoking separately increase risk, and their joint effects are particularly hazardous.

34 ic of this condition, but their separate and joint effects are uncertain.

35 s an uncritical acceptance of multiplicative joint effect as the biologically meaningful no-interacti

36 further sheds new lights on their potential joint effects as a community in disease development.

37 nalysis refined the sJIA association, with a joint effect at rs1400986 and rs4129024 in intron 1 of M

38 as focused on methods that take into account joint effects at interacting loci.

39 vironment requires an understanding of their joint effects at low concentrations across species.

40 S (per SD) and TRAP exposure (per IQR), with joint effects based on low (quartiles 1-3) and high (qua

41 synergism with family history of asthma, the joint effect being stronger with higher exposure levels.

42 ditionally, we observed a more than additive joint effect between AL and polygenic risk score (PRS) o

43 There was a joint effect between the PNPLA3 and GCKR SNPs, explainin

44 Also observed were joint effects between gamma-radiation-induced increases

45 We also investigated potential joint effects between NO (2) exposure and ADRB2 5'-UTR m

46 In contrast, no joint effects between plasma levels of Lp(a) and other c

47 There were joint effects between the variant IL-6 genotypes and smo

48 features include network diagrams that show joint effects between variants for each trait and region

49 e exposures can reveal novel synergistic and joint effects, but no study has examined the joint assoc

50 multivariable-adjusted analyses considering joint effects by BMI and ARDI, compared with women with

51 Their joint effect, called "inductive bias," determines how we

52 These tests become less optimal if the joint effect cannot be approximated adequately by the ad

53 iveness study of state firearm policies, the joint effect estimates of combinations of firearm laws w

54 f underlying mechanisms, and analysis of the joint effects for identifying combinations with the most

55 the authors conducted a ranking analysis of joint effects in which the sums and differences of the p

56 cy virus (HIV) treatment outcomes, yet their joint effect is not known.

57 a negative effect on a focal species, their joint effect is typically not given by the sum of the ef

58 Our first task, when studying joint effects, is to understand the limitations of our d

59 graphical interpretation: Curves of constant joint effect (isoboles) must be negatively sloped straig

60 rinsulinemia, but that their independent and joint effects may be associated with small increases in

61 The existing joint-effects methods also have limitations.

62 A joint effect model considered FEV(1)%pred and DLco %pred

63 A joint effect model showed adjusted RR of PPCs was highes

64 nts before transplantation was determined by joint-effect model (based on Model for End-Stage Liver D

65 ypical estimates of mutation parameters, the joint-effect model can explain data from laboratory expe

66 the patterns of predicted responses for the joint-effect model now become close to those of the infi

67 basis of empirical knowledge of mutations, a joint-effect model of pleiotropic and real stabilizing s

68 lation at mutation-selection balance under a joint-effect model of real stabilizing and pleiotropic s

69 alysis did not provide clear support for the joint-effect model or a clear case for rejection.

70 ait, as supported by the available data, the joint-effect model predicts a significantly higher V (G)

71 ion, and a pleitropic effect on fitness (the joint-effect model).

72 ) and high (> 75th percentile), and assessed joint effect modification by social support and networks

73 Kernel-based tests (KBT), which evaluate the joint effect of a group of genetic variants, are therefo

74 pairs of markers and have not considered the joint effect of a group of markers beyond these pairwise

75 We aimed to assess the joint effect of a proof-of-vaccination requirement, ince

76 of this approach is that it cannot model the joint effect of a set of SNPs on a set of genes, which m

77 of this approach is that it cannot model the joint effect of a set of SNPs on a set of genes, which m

78 The results indicate a possible joint effect of activation ability of aerosol particles,

79 nondemented people, there is only a marginal joint effect of AD genes on memory independent from APOE

80 The joint effect of aHSILs and nadir CD4 cell count <=200/uL

81 However, simultaneously modeling of the joint effect of all 61 SNPs in 7 nicotinic acetylcholine

82 cs at unmeasured eQTLs and (ii) test for the joint effect of all measured and imputed eQTLs in a gene

83 ed functional variants and (ii) test for the joint effect of all measured and imputed functional vari

84 if presence in large sequences, based on the joint effect of all such features.

85 The adjusted odds ratio for the joint effect of antecedent depression and chronic physic

86 Modeling the joint effect of bedding and bedroom floor endotoxin on r

87 We find a dominant joint effect of climate and soil on trait variation.

88 rnel machine regression (BKMR), to study the joint effect of coexposure to arsenic, manganese, and le

89 e of this study is to explore individual and joint effect of comprehensive dietary habits and lifesty

90 The joint effect of coronary artery calcification-SNPs was a

91 The joint effect of DGI and obesity was also examined.

92 rsity among paleodrainages correspond to the joint effect of differences in the area encompassed by,

93 To study the joint effect of drug heterogeneity, growth rate, and evo

94 genes or haplotype blocks, then testing the joint effect of each SNP set.

95 ults are consistent with the hypothesis of a joint effect of estrogen receptor beta sequence variants

96 The idea is that if the joint effect of exposure and genotype on risk is submult

97 Magnetism typically arises from the joint effect of Fermi statistics and repulsive Coulomb i

98 The joint effect of gestational age and Apgar score on the r

99 The joint effect of high DGI and obesity provided evidence o

100 However, the joint effect of hyperhomocysteinemia (HHcy) and hypergly

101 We aimed to assess the joint effect of in utero exposure to arsenic, manganese,

102 nalyses were performed to further assess the joint effect of landscape metrics at the school and indi

103 Here, we examine the individual and joint effect of longitudinal circulating phosphate, para

104 ge by two-stage models, and 4) the nonlinear joint effect of longitudinal MetSyn components by a part

105 We observed a joint effect of low soil water content and phenanthrene

106 There was a joint effect of maternal and paternal age with increasin

107 This 16-year longitudinal study explored the joint effect of mitigating cognitive decline in a cohort

108 il now, no models exist that can predict the joint effect of mixtures including synergists.

109 mple-specific information, and considers the joint effect of multiple enhancers.

110 need to develop more tools for assessing the joint effect of multiple genetic variants.

111 gression model are widely used to assess the joint effect of multiple predictors on a disease outcome

112 small portion of variability in disease, the joint effect of multiple variants in a pathway on diseas

113 endelian randomization (MR) and explored the joint effect of overweightness and early pubertal matura

114 portantly, for the first time, we report the joint effect of Parvimonas micra and Parvimonas sp. (p =

115 ependent effect of physical activity and the joint effect of physical activity and adiposity on HF ri

116 In the replication cohort, a joint effect of PILRA and PILRA x GM 17/17 was observed

117 utation approach was applied to estimate the joint effect of PM2.5 constituents.

118 When assessing the joint effect of race/ethnicity and socioeconomic disadva

119 We examined the joint effect of retinal abnormalities and microalbuminur

120 However, the joint effect of risk variants identified subgroups of th

121 Since gene expression levels reflect the joint effect of several underlying biological functions,

122 The joint effect of silica and smoking was more than additiv

123 The joint effect of smoking and asbestos alone was additive

124 okers, and 1.97 (95% CI: 1.73, 2.22) for the joint effect of smoking and obesity on mortality.

125 This study examines the joint effect of substance abuse and medication noncompli

126 uantile sum (WQS) regression that estimate a joint effect of the mixture components.

127 ociations between genetic risk scores of the joint effect of the SNPs and of all calcification were i

128 evidence for association was found when the joint effect of the two genes was considered.

129 is consistent with previous studies, and the joint effect of the two loci is still greater in the hig

130 Strikingly, in examining the joint effect of these alterations, we observed a >30-fol

131 However, the joint effect of these maternal conditions on child asthm

132 The joint effect of total cholesterol SNPs, low-density lipo

133 In conclusion, a joint effect of two PSCA SNPs, rs2294008 and rs2978974,

134 A framework describing the joint effect of user topography behavior and product cha

135 There is currently no tool for assessing the joint effect of vision and hearing impairment on spatial

136 en of disease and injury attributable to the joint effects of 20 selected leading risk factors in 14

137 odds ratios (ORs) and 95% CIs for AMD by the joint effects of 25(OH)D (<12, >/=12 to <20, >/=20 to <3

138 For the joint effects of 25(OH)D level and vitamin D intake, the

139 k estimates were dramatically increased with joint effects of 4 or more than 4 Markov Blanket genes.

140 ingle-marker analysis cannot accommodate the joint effects of a large number of markers.

141 demonstrate a new approach to estimating the joint effects of a mixture: quantile g-computation.

142 is) are usually more powerful to examine the joint effects of a set of SNPs on the phenotype of inter

143 Understanding joint effects of adverse exposure mixtures will facilita

144 This study investigated the individual and joint effects of air pollutants on circulating proteins

145 The separate and joint effects of alcohol and smoking on incidences of li

146 However, the global CAD PRS summarizes the joint effects of all the markers in the genome, masking

147 an, we tested effects of individual alleles; joint effects of alleles at multiple loci; epistatic eff

148 sistant strain genome allows analysis of the joint effects of alleles of different loci in isolation,

149 was conducted to examine the individual and joint effects of ambient PM2.5 exposures and MPBMI on th

150 We estimated joint effects of antiretroviral therapy (ART) initiation

151 The joint effects of any 2 types of physical activity on HF

152 This variation resulted from idiosyncratic joint effects of assembly sequence, productivity and spe

153 on health status, etiological pathways, and joint effects of associated conditions.

154 We investigated independent and joint effects of B vitamin intake as well as two polymor

155 Joint effects of biological (parasite) and chemical (Se)

156 Here, we explicitly model the joint effects of biologically coherent collections of ge

157 he associations between boron intake and the joint effects of boron intake and HRT on lung cancer ris

158 ary boron intake and lung cancer risk or the joint effects of boron intake and HRT use on lung cancer

159 -exposure mixture methodology to investigate joint effects of both exposure classes on child behavior

160 environmental driver, which allows studying joint effects of buffering and lability.

161 logistic regression was used to estimate the joint effects of C-reactive protein elevations and dysli

162 Multivariate analysis of the joint effects of changes in the six chromosomal regions

163 literature, including assessment of possible joint effects of cigarette smoking and fine particulate

164 We explored the joint effects of cigarette smoking and PMRT on LC risk.

165 onents and factors were used to estimate the joint effects of cognitive phenotypes polygenic scores (

166 ,5-b]pyridine: dose-related variation in the joint effects of common dietary carcinogens.

167 The joint effects of common variants in genomic regions cont

168 ion-based cohort large enough to examine the joint effects of EBV with other factors including age, s

169 Our results draw attention to the joint effects of ecological and endogenous selection in

170 to examine the independent associations and joint effects of education and poverty with self-reporte

171 Analyses of joint effects of eGFR and dipstick proteinuria showed th

172 tation on vegetation growth is driven by the joint effects of elevated plant N demand and gaseous N l

173 stigators have addressed health disparities, joint effects of environmental and social determinants,

174 iologically motivated by our interest in the joint effects of epigenetic methylation loci and their a

175 esity, but few studies have investigated the joint effects of exposure to SHS and diet.

176 ic and environmental conditions, to test the joint effects of fertilization and aboveground mammalian

177 The joint effects of formulation and baking conditions on re

178 trend effect of genotype and 2) the additive joint effects of gene and environment.

179 th malaria exposure, possibly because of the joint effects of gene conversion and balancing selection

180 riad design faces limitations when examining joint effects of genetic and environmental factors.

181 The joint effects of genetic, ocular, and environmental vari

182 We assessed the joint effects of germline genetic variations through a p

183 nspace provision, and 53% is associated with joint effects of greenspace provision and spatial config

184 Our goal was to estimate the independent and joint effects of heatwaves and fine particulate matter [

185 Finally, we find that the joint effects of historical changes in life history and

186 dified such that they accurately predict the joint effects of hitchhiking and background on linked, n

187 , surprisingly few studies have explored the joint effects of host and parasite richness on disease r

188 ration of this ResNet, and understanding the joint effects of its architecture and learning rules, e.

189 ious reports, we found no association of the joint effects of Leu271 and Thr541 (odds ratio, 1.04; 95

190 We examined independent and joint effects of lifestyle risk factors on fatty liver i

191 Joint effects of loss of ANXA7 and gain of EGFR expressi

192 We evaluated the independent and joint effects of metabolic traits on the risk of cirrhos

193 Joint effects of mixtures containing pharmacologically d

194 Joint effects of mixtures with fenarimol, testosterone,

195 st be accelerated and should investigate the joint effects of multiple domains of racism (structural,

196 CTGDR method, we are able to account for the joint effects of multiple genes/SNPs, whereas most exist

197 the hierarchical structure, accommodates the joint effects of multiple markers, and is computationall

198 on with metabolomics to assess the potential joint effects of multiple PFAS chemicals on the human me

199 These estimates may represent the joint effects of multiple QTL within a single interval (

200 Therefore, while joint effects of multiple species are often non-additive

201 ach other through pairwise interactions, the joint effects of multiple species on a single (focal) sp

202 ood level determinations should consider the joint effects of non-stationary tides and mean sea level

203 ive in the present study was to estimate the joint effects of obesity and smoking on all-cause mortal

204 oled Analysis of Case-Control Studies on the Joint Effects of Occupational Carcinogens in the Develop

205 ural models, to identify the independent and joint effects of OST and HAART on all-cause as well as d

206 We determine the independent and joint effects of OST and HAART on mortality, by cause, w

207 and is designed to reflect both marginal and joint effects of OTUs associated with the risk of CRC to

208 ality and morbidity, after adjusting for the joint effects of patient age, weight, pre- and postopera

209 We examined the joint effects of personal preference of dietary treatmen

210 are exposed to multiple PFAS, the potential joint effects of PFAS on the metabolome remain largely u

211 We quantified the individual and joint effects of PM2.5 exposure with MPBMI on COWO, defi

212 ith and without rare CNVs were compared, and joint effects of PRS and CNVs on schizophrenia liability

213 y data from Cedar Creek, USA, to examine the joint effects of pulse soil disturbance and press nitrog

214 To gain a better understanding of the joint effects of purifying selection and population stru

215 The joint effects of red and orange microbial clusters were

216 are achieved in the year 2025, adjusting for joint effects of risk factors.

217 his article, we focused on the impact of the joint effects of RNA-seq pipelines on gene expression es

218 Similarly, multiple-SNPs analysis revealed joint effects of rs2134655, rs172677 and rs1079597, with

219 d rate of recombination, suggesting that the joint effects of selection and linkage are important in

220 e we report results of a study to assess the joint effects of selection, recombination, and gene flow

221 question in humans by fitting a model of the joint effects of selective sweeps and background selecti

222 timate exposure-disease associations and the joint effects of silica exposure and smoking on risk of

223 ompanying article, Turner et al. compare the joint effects of smoking and air pollution to make infer

224 Evaluating absolute risks resulting from the joint effects of smoking and genetic factors is critical

225 estimate odds ratios for the independent and joint effects of smoking and PMRT on risk of overall, ip

226 Adjusted odds ratios for the joint effects of smoking and PMRT were 10.5 (95% CI, 2.9

227 vels of occupational silica exposure and the joint effects of smoking and silica exposure on lung can

228 Results suggest joint effects of specific loci on 5q and 4q, with an ove

229 egression analysis examined the separate and joint effects of the antioxidants on the ratio of forced

230 itive logistic model was used to examine the joint effects of the genotype and GxSex interaction.

231 ngestion rates, and growth) to the predicted joint effects of the mixed stressors based on the indepe

232 In multivariate analysis, the joint effects of the professional groups' scores were as

233 ssion model; recalibrating the intercept and joint effects of the prognostic factors; re-estimating a

234 tal disease burden in 2000 resulted from the joint effects of the risk factors considered.

235 However, data evaluating the joint effects of these 2 conditions on mortality are spa

236 rk has examined the possible independent and joint effects of these factors upon reward learning.

237 The joint effects of these laws indicate that the restrictiv

238 Having a better understanding of the joint effects of these trends on longevity and quality o

239 In order to understand the joint effects of TNT and RDX on earthworms, an important

240 ed biological aging and further assessed the joint effects of tobacco exposure and genetic susceptibi

241 ration-addition concept accurately predicted joint effects of two different mixtures: one containing

242 se findings improve our understanding of the joint effects of vaccination and physical distancing wit

243 Hepatocellular carcinoma may result from the joint effects of viruses and hepatotoxic chemical carcin

244 This study considered the separate and joint effects of vitamin C, vitamin E, beta-carotene, an

245 fied a module of 91 genes with a significant joint effect on childhood-onset asthma (P < 10(-5)).

246 This joint effect on different pathways may be of concern for

247 However, all methods, including our own Joint Effect on Phenotype of eQTL/functional single nucl

248 We propose joint effect on phenotype of eQTL/functional SNPs associ

249 in focal predator species and analysed their joint effect on predator and prey survival, biomass and

250 nes in the network are more likely to have a joint effect on the relevant biological processes.

251 However, race, sex, and SES had joint effects on adiposity levels.

252 To examine their joint effects on diarrheal disease and how these effects

253 iversity changes occur in concert, but their joint effects on ecological stability of natural food we

254 ) had significant single effects and several joint effects on FPP.

255 ystems, and the emergent properties of their joint effects on insect herbivores inform theory on mult

256 s were conducted to test the hypothesis that joint effects on population growth rates could be predic

257 cardiac activity, we investigated here their joint effects on tactile perception.

258 We also observed significant locus-locus joint effects on the risk, which may be mediated by the

259 Our findings suggest that the joint effects on well-being of national and global ident

260 We examined heterogeneity in joint effects (on the additive scale) between heat and o

261 Metrics of the impact of joint effects or comparisons of joint effects presented

262 Joint effect ORs were adjusted for age, smoking, iris pi

263 he impact of joint effects or comparisons of joint effects presented in units of absolute risk, such

264 tal asthma; and 12.69 (3.44-46.91) for their joint effect (relative excess risk due interaction, 9.08

265 e often been studied in isolation, and their joint effect remains poorly understood.

266 onto the same dendrite would diminish their joint effect, resulting in sublinear summation.

267 Furthermore, the joint effects revealed that high-polygenic risk score pa

268 esult, we identified 205 module genes with a joint effect significantly associated with schizophrenia

269 When testing against multiplicative joint effects, the case-only design offers excellent pow

270 type 2 diabetes; however, whether they exert joint effects to exacerbate type 2 diabetes risk is unkn

271 using polytomous logistic regression models, joint effects using self-organizing maps, and principal

272 preterm birth, and departures from additive joint effects were assessed using the relative excess ri

273 of genetically predicted BMI, WC, and their joint effect with all-cause mortality, cardiovascular di

274 dently related to AMD, with a multiplicative joint effect with genotype on AMD risk.

275 erodynamic diameter <2.5 mum; PM2.5) and its joint effect with the mother's prepregnancy body mass in

276 cularly commuting physical activity, and its joint effects with body mass index on colon cancer risk

277 eep duration and incident MI, accounting for joint effects with other sleep traits and genetic risk o

278 and conducted analyses to investigate their joint effects with plasma and dietary markers of folate

279 and long (>9 h) sleep duration, and examined joint effects with sleep disturbance traits and a corona