コーパス検索結果 (left1)
通し番号をクリックするとPubMedの該当ページを表示します
1 k(=S) for alumina was 2.42 x 10(4) and 2.03 x 10(4) m(-2
2 k(on) and k(off) values varied greatly between the nine
3 conformational diffusion upon reaction (8.0 k(B)T to 3.4 k(B)T), which occurs across the entire pept
4 inhaled air stepwisely (pO(2); 21.25 kPa (0 k), 16.42 kPa (2 k), 12.63 kPa (4 k) and 9.64 kPa (6 k))
6 esity (1.9+/-0.3 versus 2.2+/-0.2, P<0.001), k(f)(Ckrest) was 33% higher (0.23+/-0.07 s(-1) versus 0.
7 oth the random effects (g = 0.33; P = 0.015; k = 17; CI = 0.07-0.60) and bootstrap models (g = 0.32;
8 al anomaly (N=23,300, k=11; prevalence=4.1%, k=11; odds ratio=1.81, 95% CI=1.35-2.41; number needed t
9 calculate the kinetic rate constants K (1), k (2), k (3), and k (4) The analysis was repeated with t
12 omalies (N=1,348,475, k=12; prevalence=1.2%, k=9; odds ratio=1.86, 95% CI=1.16-2.96; NNH=71, 95% CI=4
13 ate the kinetic rate constants K (1), k (2), k (3), and k (4) The analysis was repeated with truncate
14 igher odds of spontaneous abortion (N=1,289, k=3, prevalence=8.1%; odds ratio=3.77, 95% CI=1.15-12.39
16 an intraclass correlation coefficient (ICC(3,k)) of 0.783 (95% confidence interval [CI]: 0.743, 0.817
17 er odds of any congenital anomaly (N=23,300, k=11; prevalence=4.1%, k=11; odds ratio=1.81, 95% CI=1.3
18 al diffusion upon reaction (8.0 k(B)T to 3.4 k(B)T), which occurs across the entire peptide, independ
19 the fluctuation of external work is above 4 k(B)T, which is easily observable in biomolecular intera
21 2-77) and of cardiac anomalies (N=1,348,475, k=12; prevalence=1.2%, k=9; odds ratio=1.86, 95% CI=1.16
22 D) reveal second-order behavior, k(H) = 0.5, k(D) = 0.08 M(-1) s(-1) (THF, -80 degrees C); thus, the
23 lized on an Food and Drug Administration 510(k)-cleared platform otherwise used for cancer diagnostic
25 16, z = -8, F13.51, TFCE((1, 54)) = 771.68, k = 70, P(FWE) = 0.044) resulting from a positive associ
27 a (coordinates, 44, 14, -14 and -38, 20, -8; k=2,102 and k=1,305, respectively) and cingulate cortex/
28 that performs maximum likelihood analyses, a k-mer-based set difference algorithm, and random forest
29 e enzyme evidenced by a K(I) = 2.2 muM and a k(inact) = 0.15 min(-1), and a partition ratio of 14.
32 cision tree, and Random Forest (RF), using a k-fold cross validation to assess the model's generaliza
34 xes for water oxidation at neutral pH with a k(obs) of 140 s(-1) at an overpotential of only 200 mV.
35 demonstrating efficient anti-aliasing with a k-space view-sharing technique, and proposing novel meth
37 ysis and formation reactions (Cl2 + H2O + A- k-4k4HOCl + HA + Cl-) were necessary to accurately simul
40 e define how a multimodular scaffold, GIV (a.k.a. Girdin), titrates such inflammatory response in mac
42 broad-spectrum anticancer drug paclitaxel (a.k.a. Taxol) that is stable in cell culture and labile to
44 ers often apply rank-reduction techniques (a.k.a. empirical orthogonal functions [EOF]) to identify i
45 gh post hoc tailoring of analysis windows (a.k.a. regions-of-interest, ROIs) to landmarks in the coll
46 thm for calculating either the most abundant k isotopologue peaks of a compound or the minimal set of
50 ue, we developed a new clustering algorithm, k-hulls, that reduces heterogeneity of the convex hull.
52 rall)(HOO(*)) = 1.53 x 10(8) M(-1) s(-1) and k(overall)(NO(2)) = 1.98 x 10(8) M(-1) s(-1)), whereas i
53 es, 44, 14, -14 and -38, 20, -8; k=2,102 and k=1,305, respectively) and cingulate cortex/medial prefr
54 etic rate constants K (1), k (2), k (3), and k (4) The analysis was repeated with truncated 30-min dy
56 n binding protein-C)-sc returned pCa(50) and k(tr) to control values and abolished oscillations, but
58 peak H(2)O(2) mixing ratios to decrease and k(H(2)O(2)) to increase, suggesting that surface uptake
60 ate, via t-Stochastic Neighbor Embedding and k-means cluster analysis of surface marker expression, t
66 ar single nucleotide variants, plastomes and k-mers associated with retrotransposons reveals two inde
70 for probe design by identifying approximate k-mers that are unique to a genome or that are present i
73 ificantly outperform shallow CNNs as well as k-mer methods in the discovery of tissue-specific sites
76 ith TEMPO-H(D) reveal second-order behavior, k(H) = 0.5, k(D) = 0.08 M(-1) s(-1) (THF, -80 degrees C)
77 the long-range interaction patterns between k-mers amino acids to predict protein crystallizability.
79 , we engineer HG4, an efficient biocatalyst (k(cat)/K(M) 103,000 M(-1)s(-1)) containing key first and
80 cardiac workload led to an increase in both k(f)(CK) (+86%, P<0.001) and ATP delivery (+80%, P<0.001
82 uced the glutaminolysis rates as measured by k (3) Conclusion: (18)F-FGln dynamic PET is a sensitive
84 s also generalized to extract characteristic k-mer peptides for all the Swiss-Prot enzymes classified
86 transfer rate through creatine kinase (CK) (k(f)(CKrest)) would be increased, compensating for deple
87 erature on the propagation rate coefficient (k(p)), reveals the transition state barrier for polycarb
88 Biased agonism was assessed by comparing k(tau) values for arrestin recruitment with those for Gq
93 period IP, overall initiation rate constant k(IP), initiation oxidizability O(i), and the critical r
94 TADF) emitter with a radiative rate constant k(r) of ca. 9 x 10(5) s(-1), exceeding those of commerci
95 ment in the observed catalytic rate constant k(s) (~5 orders of magnitude) over the mononuclear analo
96 ace area >1500 m(2)/g and Langmuir constant (k(L)) > 0.1 to adsorb water vapor and meet these maximum
97 h-out traces, the association rate constant (k(1)) is somewhat decreased for both AMT and RMT in the
99 tify the SO(4)(*-) scavenging rate constant (k(=S)) for alumina, a naturally occurring mineral in soi
100 he values of the inactivation rate constant (k(d)) decreased with an increase in pH, which was relate
101 ments to measure the exchange rate constant (k(ex)) of the imino protons in the unbound, cocaine-boun
102 causes the oxidation by HOCl rate constant (k(HOCl)) to nearly double and oxidation by Cl(2) to occu
106 The resulting second-order rate constants k(2) followed the correlation log k(2)(20 degrees C) = s
107 d irreversibly, with removal rate constants (k(H(2)O(2))) 17-73 times larger than air change rate (AC
111 opy, temperature-independent rate constants (k~1.4x10(-3) s(-1) ; half-life of ~8 min) were measured
113 A publicly available dataset containing k-space data as well as Digital Imaging and Communicatio
114 ulic conductance in the soil-plant continuum k(max) (a key model parameter which is not commonly meas
115 val [CI] -1.02 to -0.63) and active control (k-9; n = 662; SMD = -0.35, 95% CI -0.56 to -0.14) at pos
116 ce PTSD symptoms more than inactive control (k = 46; n = 3,389; standardised mean difference [SMD] =
121 fitted the inactivation data with determined k(d) and particle-associated inactivation rate constant
123 this approach is contingent upon determining k(max) , it presents a mechanistic trait-based alternati
125 attachment network with degree distribution k(-lambda), where lambda = 3 for a large number of nodes
127 sampling while considering a weight for each k-mer; i.e. the higher the weight of a k-mer, the more l
128 ical (k = 9); e-health (k = 8); educational (k = 4); peer-led (k = 5); breathing re-training (k = 1).
129 ons of a significant kinetic isotope effect (k(H) /k(D) =5.7) for the reactions of diphenyl ether und
133 V/k(B)T, with a logarithmic variation for eV/k(B)T > 1, variations in accordance with the results of
134 aling of the conductance as a function of eV/k(B)T, with a logarithmic variation for eV/k(B)T > 1, va
137 tivation energy (E(a)) and frequency factor (k(0)) values were determined to be 45.9 x 10(3) kJ/kg-mo
138 e (TzB) intermediate that results from fast (k(2) : ~5000 m(-1) s(-1) ) and reversible conjugation of
139 hich displays the same activation energy for k(cat) as WT, as a control, we were able to further refi
140 gorithm for simplifying variation graphs for k-mer indexing without losing any k-mers in the haplotyp
141 8, the rate constant of Y(32)(*) formation (k(PCET)) increases by one order of magnitude per pH unit
142 dent HDX-MS profiles into contributions from k(ch)(T), as well as local and global protein dynamics.
143 ignment-free, stochastic models derived from k-mer distributions representing reference genome sequen
147 nsory (color)) > k(non-enzymatic browning) > k(vitamin C) > k(antioxidant capacity) > k (sensory (ove
148 > k(non-enzymatic browning) > k(vitamin C) > k(antioxidant capacity) > k (sensory (overall)) > k(tota
149 ) > k(vitamin C) > k(antioxidant capacity) > k (sensory (overall)) > k(total phenolics) > k(gingerols
150 s showed following order: k(beta-carotene) > k(sensory (color)) > k(non-enzymatic browning) > k(vitam
151 der: k(beta-carotene) > k(sensory (color)) > k(non-enzymatic browning) > k(vitamin C) > k(antioxidant
152 ioxidant capacity) > k (sensory (overall)) > k(total phenolics) > k(gingerols), resulting in multiple
153 k (sensory (overall)) > k(total phenolics) > k(gingerols), resulting in multiple cutoff criteria and
156 a significant kinetic isotope effect (k(H) /k(D) =5.7) for the reactions of diphenyl ether under H(2
158 types were psychological (k = 9); e-health (k = 8); educational (k = 4); peer-led (k = 5); breathing
161 % vs 70.91%), but they showed faster (higher k) in vitro starch hydrolysis (0.0140 vs 0.0050) with lo
162 he metastatic nodes had significantly higher k(3) (p value = 8.8 x 10(-8)) and K(i) (p value = 5.3 x
164 ain as reflected by significant increases in k (E,brain) (from +26% to +54% relative to baseline).
165 ivity) and (iii) improvements are present in k(cat) rather than just in K(M), suggesting adaptive sol
167 disrupts the closed conformation to increase k(off), the disulfide in M88 stabilizes the closed confo
168 off is more severe (20- to 35-fold increased k(cat)/K(M) in arylesterase with 60-400-fold decreases i
169 icient reduction of this disulfide increases k(off) 19,000-fold, thus creating a reversible redox-dep
170 mploy an alternative approach for increasing k(inact) of a lysine-targeted covalent Hsp90 inhibitor,
175 mitochondrial genome, known as kinetoplast (k) DNA, composed of mutually catenated maxi- and minicir
176 ng three machine learning algorithms (LASSO, k-nearest-neighbors, and deep-neural-networks), two gene
177 rk in a maximal set of nodes having at least k neighbours within the set, known as [Formula: see text
180 librium, Quantal Response Equilibrium, level-k cognition, fictitious play, reinforcement learning, se
181 group at posttreatment for quality of life (k = 6; n = 401; SMD = 0.33, 95% CI -0.01 to 0.66; p = 0.
182 es were substituted into the correlation log k(2)(20 degrees C) = s(N)(N + E) to determine the electr
183 constants k(2) followed the correlation log k(2)(20 degrees C) = s(N)(N + E), where electrophiles ar
189 major dithionite oxidation product, lowered k(SA) in type II system by ~10-fold via at least two mec
190 proaches including logistic regression (LR), k-nearest neighbor (k-NN), support vector machine (SVM),
191 pproximately constant at small voltages (V < k(B)T/e), while at larger voltages it increases logarith
192 ope of radioactivity washout from the lungs (k (E,lung)) was 70% lower in Abcc1 ((-/-)) rats, whereas
194 olaron pairs: k(S,s) = (44.59 +/- 0.01) MHz, k(T,s) = (43.97 +/- 0.01) MHz, and the recombination rat
195 h leaf labeled by a string of length at most k, and a binary string alignment function (x), an implie
196 time-resolved volumetric cardiovascular MRI k-space data, without a significant loss in data quality
197 ogistic regression (LR), k-nearest neighbor (k-NN), support vector machine (SVM), random forest (RF),
198 to both free nitric oxide and nitrosothiols (k (inact)/K(I) >= 5 m(-1) s(-1)), which is the first rep
199 le to that determined from thermal (1)H NMR (k = 0.050 +/- 0.003 dm(3) mol(-1) s(-1)) and UV measurem
203 orks (yielding a "U-shape" in a histogram of k-shell occupancy) provide resilience against both local
209 ges that maintain tropical and oligotrophic (k-strategist) signatures, to seasonally displace more co
211 memristors enable weight assignment based on k-means clustering, which offers greater computing accur
213 ferent mutations had differential effects on k (cat) and K (0.5) for catalysis, K (0.5) for substrate
215 d related parameters showed following order: k(beta-carotene) > k(sensory (color)) > k(non-enzymatic
217 gh occupancy of nodes in the inner and outer k-shells and low occupancy in the middle shells of finan
219 rates for singlet and triplet polaron pairs: k(S,s) = (44.59 +/- 0.01) MHz, k(T,s) = (43.97 +/- 0.01)
220 constant (K (trans)) and washout parameter (k (ep)) derived from DCE MRI were compared before and af
223 bility, proportional recovery coefficient r (k) , time constant in weeks tau (k) , and distribution o
225 f mutagenesis and selection, thereby raising k(cat)/K(m) 270-fold to 5 x 10(5)m(-1)s(-1), which is ev
226 nment tools, ranging from ultra-fast low-RAM k-mer-based database search to fully exhaustive gapped D
228 tituent lowers the force required for rapid (k(open) ~10(2) s(-1)) ring opening to ca. 900 pN, vs 130
229 re length (chi(beta)) and dissociation rate (k(off)) are extracted using the model by Friddle, De Yor
230 d that the lower membrane dissociation rate (k(off)) of Rok at the tissue boundary with low Crumbs ex
232 Moreover, we determined association rates (k(on)) and dissociation rates (k(off)), as well as NAM a
234 caled to whole body biotransformation rates (k(B)) were compared against in vivo k(B) estimates.
236 iation rates (k(on)) and dissociation rates (k(off)), as well as NAM affinities with [(3)H]methoxy-PE
237 nits were nonviable as CO(2)-fixation rates (k (cat) (c)) were reduced >95% and CO(2)/O(2) specificit
238 we find that using average homo-FRET rates (k(FRET)), average fluorescence lifetimes (tau), and aver
241 termine the rate constants of HAT reactions (k(H)), but no radical clock is available to measure the
243 e of signaling by agonist-occupied receptor (k(tau)), simply the rate of signal generation before it
244 ed the initial rate of arrestin recruitment (k(tau)), a biologically-meaningful kinetic drug efficacy
245 CI = 1.24 to 5.15, p = 0.01) and remission (k = 3, OR = 1.84, 95% CI = 1.32 to 2.57, p < 0.001) rate
247 or growth kinetics (Psi=Aexp[-(E(A) -E(s) )/(k(B) T)]) is proposed to address the surface energy and
251 s with the following apparent specificities (k (cat)/K (M)): propyl > ethyl > methyl > guaiacol.
252 duced changes of the chemical labeling step (k(ch)) from thermally enhanced protein fluctuations.
253 (k=40) and observational treatment studies (k=40), outcome measures most often assessed core FND sym
254 s implemented in C++ to compute supermaximal k-mismatch repeats directly, and show that these element
255 nificant improvement in depressive symptoms (k = 7, Hedges' g = 0.44, 95% confidence interval (CI) =
256 e most effective for reducing PTSD symptoms (k = 17; n = 1,077; mean difference = -37.95, 95% CI -60.
265 e EC classification and annotation; (ii) the k-mer-based tools (including PPR-Hotpep, CUPP and eCAMI)
267 Based on the temperature dependence of the k(ex) values, we find that MN19 is more dynamic than MN4
268 s efficient algorithm is an extension of the k-means algorithm and can be used with any type of categ
271 ral orders of magnitude more slowly than the k (cat) The presence of substrate enhanced C4a-hydropero
272 occurred with a rate constant similar to the k (cat) The structure of AsFMO complexed with FAD at 2.0
273 mer method as a special case, but unlike the k-mer method, it is convenient for Nubeam to account for
274 dition, Fluxer can compute and visualize the k-shortest metabolic paths between any two metabolites o
275 ated analyses is genome profiling, where the k-mer frequencies within raw sequencing reads are analyz
277 This phenomenon is likely to explain the 'k-hole', a state of oblivion likened to a near death exp
280 reduction methods, SkSES identifies the top k genomic variants in a cohort quickly, accurately and i
282 dent at glassy carbon and gold transducers - k(o) (standard heterogeneous rate constant) was 2.56 x 1
285 On one hand, binding (k'(on)) and unbinding (k(off)) rate constants were extracted from (1)H-(1)H exc
287 with inactive control at 6-month follow-up (k = 10; n = 738; SMD = -0.45, 95% CI -0.82 to -0.08).
290 Massachusetts, and Cincinnati, Ohio, we used k-means clustering and principal component analysis to i
292 cs with fluxomics data, we find that in vivo k (cat)s are robust against genetic perturbations, sugge
294 ic models, we show that the obtained in vivo k (cat)s predict unseen proteomics data with much higher
295 e a data-driven approach to estimate in vivo k (cat)s using metabolic specialist Escherichia coli str
297 O(*) and NO(2) scavenging activity in water (k(overall)(HOO(*)) = 1.53 x 10(8) M(-1) s(-1) and k(over
298 f of K(i) = 5.3 x 10(-3) mL/cm(3)/min, while k(3) and volume had accuracy of 0.94 (sensitivity = 0.82
299 circRNA datasets when compared with XGBoost, k-nearest neighbor, support vector machine, random fores