コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 inase (ROP18 and ROP16, respectively) is the key molecule.
2 to future structure-function studies of this key molecule.
3 s elicit pathogenesis and platelet CD40 is a key molecule.
4 adding cytokines they lacked or transfecting key molecules.
5 normal, reversed or bilateral expression of key molecules.
6 "jumpstarted" by the selective activation of key molecules.
8 idation of distinct neuronal roles played by key molecules already well known to immunologists (e.g.,
9 in imaging technology with probes that image key molecules and molecular based events that are fundam
11 complex remodelling process, with a focus on key molecules and pathways that might be suitable target
14 elegans model should yield new insights into key molecules and their possible implications in parasit
15 3 (IRF3) and nuclear factor (NF)-kB, that is key molecules and transcription factors involved in the
17 ty is associated with selective exclusion of key molecules, and that manipulation of transport can en
18 build a presynaptic terminal has been made, key molecules are recruited to assemble synaptic vesicle
20 d alopecia, we examined expression levels of key molecules associated with hair follicle differentiat
21 ionally, these cells exhibited enrichment of key molecules associated with memory potential when comp
22 of the stress response kinase p38-MAPK, both key molecules associated with ultraviolet radiation derm
25 le fundamental regulators, such as SOX9, are key molecules both in mice and humans, the way in which
26 onging to the TNF family (BAFF) represents a key molecule by which macrophages and DCs directly regul
27 ulating the metabolism of lipids through the key molecule carnitine palmitoyl transferase 1 (CPT1), i
29 tor of mitochondrial calcium uniporter, as a key molecule conferring cancer cells with resistance to
30 therapeutic dosing of AE, whereas IGF-1 is a key molecule coupled to gene expression of other molecul
31 eptor interacting protein 3 kinase (RIP3), a key molecule critical for the assembly of the necrosome
34 notherapy and biologic therapies that target key molecules driving the Th2 response are already used
35 creasing evidence have pointed out CD25 as a key molecule during this transdifferentiation process, h
39 ning the GC response in mice have identified key molecules expressed on follicular dendritic cells th
41 Thus, our findings establish IKK-gamma as a key molecule for adapting an oncoprotein-specific signal
42 llular process is still unclear, Beclin 1, a key molecule for autophagy, has been suggested to play a
44 id organ homeostasis and identify RANKL as a key molecule for controlling the plasticity of the immun
46 th 5' AMP-activated protein kinase (AMPK), a key molecule for energy sensing that negatively regulate
49 have previously identified fibronectin as a key molecule for incorporation of LTBP1 and TGF-beta int
52 d cyclophilin ligand interactor (TACI), is a key molecule for plasma cell maintenance and is required
57 ne (and related phytochelatins) could act as key molecules for ensuring the effective formation of HM
58 iced leader (SL) RNA and the large rRNAs are key molecules for mRNA maturation and protein synthesis,
59 roteins (TRAPs) that have been implicated as key molecules for parasite motility and adhesion onto ho
60 Ionotropic glutamate receptors (iGluRs) are key molecules for synaptic signaling in the central nerv
61 ese results suggest that IRS-1 and IRS-2 are key molecules for the TbetaR-V/LRP-1-mediated growth inh
63 ts the acquisition of adaptation by removing key molecules from the hair bundle that serve a temporar
64 ing chemical logic to remind how these seven key molecules function as mobile packets of cellular cur
65 These findings have identified HDAC6 as a key molecule gating the effects of acute stress on synap
68 s, stem cells and mitochondria interact with key molecules governing genome integrity, 'stemness' and
70 owever, the regulatory role of miRNAs on the key molecules implicated in kidney fibrosis remains poor
72 ifferences in the expression or induction of key molecules implicated in viral induction of interfero
75 ol regulatory element-binding protein 2 is a key molecule in aggravating proinflammatory responses in
78 component of eukaryotic cell membranes and a key molecule in controlling membrane fluidity, organizat
79 plasticity, and prostaglandin E2 (PGE2) is a key molecule in COX-2-meduated synaptic modification.
81 and degraded poly ADP ribose polymerase-1 (a key molecule in DNA repair and cell survival), leading t
82 tion of poly-ADP ribose polymerase (PARP), a key molecule in DNA repair, led to ovarian cancer patien
83 osure in CD8 T cells, with STAT4 acting as a key molecule in driving optimal antigen-specific respons
84 in gene, Rax, was previously identified as a key molecule in early eye formation in mice and humans.
85 nicotinamide adenine dinucleotide (NAD(+), a key molecule in energy and redox metabolism) decrease wi
86 n vitro and induce the expression of nNOS, a key molecule in gastrointestinal motility regulation.
87 mania spp., the spliced-leader (SL) RNA is a key molecule in gene expression donating its 5'-terminal
88 report that mice deficient in lymphotoxin, a key molecule in gut immunity, were resistant to DIO.
89 ated candidate genes and select one, EGR1, a key molecule in hippocampus-related learning and memory,
91 urther confirmed that DPP8 but not DPP9 is a key molecule in inducing cell death induced by DPP8/9 in
92 ld the acyl-NAD adduct which is considered a key molecule in INH action, providing a better understan
94 y endocytic proteins, it is not considered a key molecule in mediating the major forms of endocytosis
95 immunoglobulin E (IgE) was identified as the key molecule in mediating what are now described as type
96 ported that S-adenosylmethionine (AdoMet), a key molecule in methylation reactions and polyamine bios
98 the DRGs of diabetic mice at 8 mo of age, a key molecule in pain signaling, and this effect was also
100 r data suggest that myocardial MDA5 may be a key molecule in protecting the heart from direct viral i
102 vator receptor (uPAR) has been shown to be a key molecule in regulating plasminogen-mediated extracel
104 Importantly, PRDI-BF1 is defined as the key molecule in silencing CIITA and thus MHC-II in multi
105 These data strongly suggest that Cas-L is a key molecule in T cell migration induced by the ligation
108 nsforming growth factor-beta (TGF-beta) as a key molecule in the development and progression of hepat
110 ese results demonstrate that galectin-3 is a key molecule in the host defense against pneumococcal in
115 oid protein (Abeta) has been implicated as a key molecule in the neurodegenerative cascades of Alzhei
118 G protein-coupled receptor (KSHV-GPCR) is a key molecule in the pathogenesis of Kaposi's sarcoma, pl
120 inositol-4,5-bisphosphate (PtdIns-4,5-P2), a key molecule in the phosphoinositide signalling pathway,
124 expression of Lyn, indicating that Lyn is a key molecule in the regulation of BCR-mediated signaling
125 is a G-protein-coupled receptor (GPCR) and a key molecule in the regulation of energy homeostasis.
128 -associated protein of 25 kDa (SNAP-25) is a key molecule in the soluble N-ethylmaleimide-sensitive f
129 f cytokinesis, Plo1p is thus implicated as a key molecule in the spatial and temporal coordination of
131 AR signaling and suggest that betaARK1 is a key molecule in the transition of myocardial hypertrophy
132 our data suggest that C5a(desArg) acts as a key molecule in the triggering of local inflammation as
137 kin 1 receptor-associated kinase 1(IRAK1), a key molecule in TLR/IL-1R-mediated signaling, is phospho
138 ynthesis of S-adenosylmethionine (AdoMet), a key molecule in transmethylation reactions and polyamine
141 To validate and quantitate the expression of key molecules in a wide range of samples, we have develo
143 (cysteine-aspartate-specific proteases) are key molecules in apoptosis and require proteolytic remov
144 ctivated protein kinase, that alterations in key molecules in both GLUT4 trafficking and insulin sign
147 ng suggested that these processes controlled key molecules in glomeruli and specifically podocytes, i
148 Noncoding RNAs (ncRNAs) are emerging as key molecules in human cancer, with the potential to ser
150 summary, this study identifies SREBPs as the key molecules in regulating angiogenesis in response to
151 ogical or genetic inhibition of ROCK1 and 2, key molecules in Rho signaling, resulted in neuroblastom
153 creasingly important to the functionality of key molecules in signaling, cell growth, and cell death.
155 aromatic hydrocarbons (PAHs) are regarded as key molecules in the astrochemical evolution of the inte
156 the intracellular concentrations of several key molecules in the bone formation cascade, we examined
157 ew risk loci could lead to identification of key molecules in the development of Barrett's oesophagus
159 d protein kinase Clambda (PKC-lambda), three key molecules in the insulin-signaling pathway, and was
161 hway and cancer-related genes, we identified key molecules in the selection of TRCs, such as ATF4, SL
162 ENU (N-ethyl-N-nitrosourea), have disclosed key molecules in the TLR signaling pathways and helped u
163 ponses is poorly understood, in part because key molecules in this mode of signal transduction, the m
164 habditis elegans have implicated a number of key molecules in this process, including the nutrient-se
165 netic mechanism studies have identified more key molecules (including Osterix, beta-catenin, and soni
166 tial to life because of its role in numerous key molecules, including DNA and RNA; indeed, organisms
170 t also suppressed the expression of IL-7R, a key molecule involved in controlling intestinal ILC home
174 mice showed increased expression of RhoA, a key molecule involved in regulation of vascular tone, co
177 ancer metastasis; therefore, identifying the key molecules involved during this process promises to a
178 Macrophages deficient in WASp or Cdc42, two key molecules involved in actin core organization in pod
179 n D supplementation attenuated expression of key molecules involved in adipose tissue browning and am
180 Recent studies have highlighted some of the key molecules involved in all of these pathogenic proces
181 to evaluate the expression and activation of key molecules involved in cell survival and proliferatio
182 and ZAP-70 also associated differently with key molecules involved in cytoskeletal and calcium signa
183 temic immunosuppression by downregulation of key molecules involved in DC differentiation and suppres
185 harmacological inhibition against a panel of key molecules involved in galvanotaxis further revealed
187 mplex and its neurobiology, its relevance to key molecules involved in neurodegeneration and the pote
188 ome biosynthetic aspects of T. cruzi mucins, key molecules involved in parasite protection and virule
189 p70 can bind millions of proteins, including key molecules involved in processes of stemness, tumorig
190 he brain and thus controls the expression of key molecules involved in receptor signaling and spine m
191 t of NM, and (2) the expression of two other key molecules involved in regulating neuronal [Ca(2+)](i
192 r adapters capable of binding to enzymes and key molecules involved in signal transduction, maintaini
196 Transcriptomics revealed downregulation of key molecules involved in T cell receptor (TCR) signalin
197 NA microarray analysis is starting to reveal key molecules involved in the accumulation of free chole
198 ated in part through increased expression of key molecules involved in the class II MHC pathway via i
199 in the striatum, we suggest that they may be key molecules involved in the expression of the dyskines
200 Wiskott-Aldrich syndrome protein and Cdc42, key molecules involved in the formation of actin-based p
201 on on Th17 cells and inhibited expression of key molecules involved in the generation of pathogenic T
202 aken together, these results have identified key molecules involved in the group II mGluR-induced pot
205 gnaling systems as well as the processing of key molecules involved in the pathology of the disease.
208 wn mechanisms by which ATP and adenosine are key molecules involved in thrombosis by regulating the a
209 mad signaling pathway, and the production of key molecules involved in tissue repair, such as type I
211 hich is abundant in spontaneous tumors, as a key molecule limiting this IFN-induced tumor regression
215 results indicate that the OAMB receptor is a key molecule mediating the octopamine's signal for appet
216 monstrating that Nemo-like kinase (NLK) is a key molecule modulating disease toxicity in spinocerebel
217 e forkhead transcription factor, FoxP3, is a key molecule necessary and sufficient for Tregs developm
219 r animal models, have identified some of the key molecules necessary for peripheral innervation and f
220 ed that Meis1 regulates the transcription of key molecules necessary for the endosomal machinery.
221 that RB deficiency altered the expression of key molecules needed for proper cellular organization an
222 ic, stochastic noise in small populations of key molecules (notably, Period mRNA near its daily minim
226 cell death converging at anoikis, including key molecules of interaction such as Beclin 1, reactive
227 nosaialic acids, is thought to be one of the key molecules of signal transduction in mammalian cells.
229 trate a sex-specific interaction between two key molecules of the human serotonergic system, and sugg
232 for characterizing the interactions between key molecules of the slit diaphragm that control glomeru
233 e of motor neurons in ALS and that targeting key molecules of this cascade may prove to be neuroprote
234 he muscle-specific kinase MuSK is one of the key molecules orchestrating neuromuscular junction (NMJ)
235 to bromodomain, testis-specific (Brdt) as a key molecule participating in chromatin remodeling durin
236 ve response may be determined, in part, by a key molecule, periostin, which maintains the integrity o
240 rtive activity, suggesting that IGF-2 is the key molecule produced by these cells that stimulates HSC
242 proach with the kinase hits identified other key molecules putatively involved in tau phosphorylation
248 Thus, our study has shown that Dcc is a key molecule required for ventral migration of early-bor
249 patients with PIK3CD GOF mutations, identify key molecules required for cell-mediated immunity agains
253 d phospholipase A2 group IB (PLA2G1B) as the key molecule responsible for the formation of aMMDs.
255 ype NPCs, suggesting that TSP1 is one of the key molecules responsible for astrocyte-induced neurogen
258 apparently result in the down-regulation of key molecules, such as cyclin A, which may be responsibl
260 our knowledge, cyclin D3 is identified as a key molecule targeted by autoimmunity that plays a nonre
262 e-acetylglucosaminyltransferase (LARGE) is a key molecule that binds to the N-terminal domain of alph
265 s identifying adenosine deaminase (ADA) as a key molecule that delineates a human Tfh helper program
267 ty of cyclic AMP-dependent protein kinase, a key molecule that is known to be involved in L-LTP.
268 ogether, our results support that TRAF6 is a key molecule that mediates the interaction between melan
269 S, a member of the CD28 family, represents a key molecule that regulates adaptive responses to foreig
273 were combined with RNA-seq data to identify key molecules that associate with long-term durable self
276 istinct microenvironmental niches to provide key molecules that drive innate and adaptive immune resp
278 terations in the expression of Fgf8 and Shh, key molecules that establish a signaling center critical
279 y novel components of the pathway, including key molecules that function as positive or negative regu
280 ding proteins profilin and thymosin beta4 as key molecules that localize actin monomers to the leadin
281 pe 2 BBZDR/Wor rats changes in expression of key molecules that make up the nodal and paranodal appar
283 ppaB kinase alpha (IKKalpha) and IKKbeta are key molecules that predominantly mediate noncanonical an
284 d liver sinusoidal endothelial cells express key molecules that recruit and activate innate and adapt
287 data demonstrate a functional link between 2 key molecules that regulate hypoxia preconditioning and
289 alian target of rapamycin complex 1 serve as key molecules that sense cellular energy and nutrients l
291 ll proliferation and differentiation and are key molecules that target retinoid and retinoic acid rec
292 , phosphorylate and regulate the activity of key molecules that ultimately control the expression of
294 stence in their hosts while also revealing a key molecule to pursue while devising methods to improve
297 gulation factors, such as myosin-1, serve as key molecules to link phosphatidylinositol signals to po
298 of Trk, identifying Rac GTPase as one of the key molecules whose activity is critical for cell surviv
299 r applicability of this approach for linking key molecules with defined cellular functions in another
300 ion pathways and that, specifically, several key molecules within the mitogen-activated protein kinas