ライフサイエンスコーパス: knee osteoarthritis

1 erally administered for pain associated with knee osteoarthritis).

2 275A) mice predisposes to the development of knee osteoarthritis.

3 luronic acid, is widely used for symptomatic knee osteoarthritis.

4 rventions for community-dwelling adults with knee osteoarthritis.

5 is essential for evaluation of synovitis in knee osteoarthritis.

6 knee injuries increase the risk for incident knee osteoarthritis.

7 th inequality and malalignment with incident knee osteoarthritis.

8 valence ratios for knee pain and symptomatic knee osteoarthritis.

9 eported pain were used to define symptomatic knee osteoarthritis.

10 associated with increased risk of developing knee osteoarthritis.

11 who underwent elective surgery due to severe knee osteoarthritis.

12 rior knee radiography to define radiographic knee osteoarthritis.

13 e difficulty in identifying risk factors for knee osteoarthritis.

14 alent, incident symptomatic, and progressive knee osteoarthritis.

15 population and may accelerate development of knee osteoarthritis.

16 is a potentially modifiable risk factor for knee osteoarthritis.

17 y of individuals who have or are at risk for knee osteoarthritis.

18 l interventions among African-Americans with knee osteoarthritis.

19 ets for both prevention and intervention for knee osteoarthritis.

20 es were prevalent, incident, and progressive knee osteoarthritis.

21 d for quantifying changes in tibiofemoral in knee osteoarthritis.

22 viduals who have or who are at high risk for knee osteoarthritis.

23 waiting list control group for patients with knee osteoarthritis.

24 rt-term benefits of acupuncture for treating knee osteoarthritis.

25 ay possibly be more important in hip than in knee osteoarthritis.

26 uded in the treatment plan for patients with knee osteoarthritis.

27 nction in patients with existing symptomatic knee osteoarthritis.

28 a role in the management of unicompartmental knee osteoarthritis.

29 ortant in the development and progression of knee osteoarthritis.

30 d improve the symptoms of medial compartment knee osteoarthritis.

31 ave the potential to improve the symptoms of knee osteoarthritis.

32 the mechanisms for the production of pain in knee osteoarthritis.

33 function in patients with medial compartment knee osteoarthritis.

34 impact on the development and progression of knee osteoarthritis.

35 e obese 45-64-year-old women with unilateral knee osteoarthritis.

36 sical therapy treatment for individuals with knee osteoarthritis.

37 hening is a common goal in the management of knee osteoarthritis.

38 ve in improving balance in older adults with knee osteoarthritis.

39 ed 65 and older have radiographic changes of knee osteoarthritis.

40 ngly associated with the presence of pain in knee osteoarthritis.

41 er (aged 65-74 years), obese, or had hand or knee osteoarthritis.

42 d be prescribed as part of the treatment for knee osteoarthritis.

43 eoarthritis; 9.5% of adults aged > 62 y have knee osteoarthritis.

44 glucocorticoid injections for patients with knee osteoarthritis.

45 d volume-via MRI is essential for monitoring knee osteoarthritis.

46 not associated with symptomatic radiographic knee osteoarthritis.

47 20 to 45 and with knee pain and radiographic knee osteoarthritis.

48 eliver group PT to patients with symptomatic knee osteoarthritis.

49 ill enhance health outcomes of patients with knee osteoarthritis.

50 ature of cartilage aging, a leading cause of knee osteoarthritis.

51 dely used, with some evidence of efficacy in knee osteoarthritis.

52 icient for delivering exercise therapies for knee osteoarthritis.

53 537 outpatients with symptomatic hip or knee osteoarthritis.

54 this treatment for patients with symptomatic knee osteoarthritis.

55 progression of structural characteristics of knee osteoarthritis.

56 ely treat long-term pain and disability from knee osteoarthritis.

57 otwear is recommended for self-management of knee osteoarthritis.

58 r improving WOMAC knee pain in patients with knee osteoarthritis.

59 d physical function in patients with hip and knee osteoarthritis.

60 urse of physical therapy in the treatment of knee osteoarthritis.

61 e use of zoledronic acid in the treatment of knee osteoarthritis.

62 lticenter study in patients with symptomatic knee osteoarthritis.

63 be a valid alternative treatment for chronic knee osteoarthritis.

64 ge insoles as a treatment for pain in medial knee osteoarthritis.

65 ol condition in patients with painful medial knee osteoarthritis.

66 h a degenerative medial meniscus tear and no knee osteoarthritis.

67 ing 45 blacks and 49 whites with symptomatic knee osteoarthritis.

68 l to the development of pain associated with knee osteoarthritis.

69 njection or no intervention in patients with knee osteoarthritis?

70 Among patients with symptomatic knee osteoarthritis, 2 years of intra-articular triamcin

71 of the US population is affected with hip or knee osteoarthritis; 9.5% of adults aged > 62 y have kne

72 ited participants 50 to 85 years of age with knee osteoarthritis according to the American College of

73 alence of diseases affecting cartilage (e.g. knee osteoarthritis affecting 16% of population globally

74 then tested in 62 individuals affected with knee osteoarthritis and 52 age matched controls and test

75 d trial with participants aged >50 y who had knee osteoarthritis and a body mass index [BMI (in kg/m(

76 415 persons with symptomatic knee osteoarthritis and a body mass index between 28 and

77 buckling is common in persons with advanced knee osteoarthritis and after orthopedic procedures.

78 nctionality and pain of patients with hip or knee osteoarthritis and arthroplasty and analyze the ass

79 Among patients with symptomatic knee osteoarthritis and bone marrow lesions, yearly zole

80 summarizes recent literature about obesity, knee osteoarthritis and joint pain.

81 0 to 85 years with symptomatic, radiographic knee osteoarthritis and Kellgren-Lawrence grade 2 or 3.

82 Participants with symptomatic knee osteoarthritis and low 25-hydroxyvitamin D (12.5-60

83 Among patients with symptomatic knee osteoarthritis and low serum 25-hydroxyvitamin D le

84 proach by estimating the association between knee osteoarthritis and mortality.

85 ate quality-adjusted life-year losses due to knee osteoarthritis and obesity in comparison with the r

86 of quality-adjusted life-years lost owing to knee osteoarthritis and obesity seems to be substantial,

87 Policy Model, a computer simulation model of knee osteoarthritis and obesity, was used to estimate qu

88 Among patients with knee osteoarthritis and overweight or obesity, diet and

89 ng risk factors for incident and progressive knee osteoarthritis and related knee pain to identify ta

90 s examined associations between radiographic knee osteoarthritis and serum levels of alpha-, delta-,

91 ults aged 50 years or older with symptomatic knee osteoarthritis and subchondral bone marrow lesions

92 o estimate associations between radiographic knee osteoarthritis and tertiles of each tocopherol meas

93 The development of symptomatic knee osteoarthritis and the progression of joint space l

94 ents or interventions used for patients with knee osteoarthritis and their potential effects on pain

95 Associations between radiographic knee osteoarthritis and tocopherol isoforms are complex

96 Quality-adjusted life-years lost due to knee osteoarthritis and/or obesity represent 10% to 25%

97 onic pain conditions (chronic low back pain, knee osteoarthritis, and fibromyalgia).

98 risk factor for structural deterioration in knee osteoarthritis, and its relation to progression is

99 mass (in kilograms) and its change, painful knee osteoarthritis, and reduced quadriceps strength.

100 In 2000, body composition, x-ray-defined knee osteoarthritis, and self-reported knee pain informa

101 r for African-Americans than Caucasians with knee osteoarthritis, and some contributing factors have

102 sted prevalence of knee pain and symptomatic knee osteoarthritis approximately doubled in women and t

103 Obesity and knee osteoarthritis are among the most frequent chronic

104 While factors affecting the course of knee osteoarthritis are mostly unknown, lesions on bone

105 erol ratio had half the odds of radiographic knee osteoarthritis as those in the lowest tertile (adju

106 ) do not halt the progression of symptomatic knee osteoarthritis, as was previously suggested.

107 e accurate and cost-effective diagnostics of knee osteoarthritis at the primary healthcare level.

108 In this trial involving patients without knee osteoarthritis but with symptoms of a degenerative

109 plementation is associated with benefits for knee osteoarthritis, but current trial evidence is contr

110 e size of bone marrow lesions in people with knee osteoarthritis, but data from large trials are lack

111 rvention improved outcomes for patients with knee osteoarthritis, but it did not assess separate effe

112 physical function in people with symptomatic knee osteoarthritis, but the benefits of this therapy ar

113 es weight effectively in obese patients with knee osteoarthritis, but the role of LED in long-term we

114 The cumulative incidence of knee osteoarthritis by 65 years of age was 13.9% in part

115 Late-stage isolated medial knee osteoarthritis can be treated with total knee repla

116 The frequency of knee osteoarthritis continues to accelerate, likely beca

117 The number of new patients seen for knee osteoarthritis decreased by 6.7%, whereas the numbe

118 undergoing total knee arthroplasty (TKA) for knee osteoarthritis develop debilitating knee stiffness

119 obesity is equivalent for the development of knee osteoarthritis; development appears to be strongly

120 te for differential misclassification of the knee osteoarthritis diagnosis and confounding from unmea

121 ee osteoarthritis increased but radiographic knee osteoarthritis did not.

122 ded to deliver exercise-related services for knee osteoarthritis efficiently and according to patient

123 Zurich Multiple Endpoint Vitamin D Trial in Knee Osteoarthritis enrolled adults aged >=60 y who unde

124 d-tear' condition, it is now recognized that knee osteoarthritis exists in the highly metabolic and i

125 nutritional supplements in the management of knee osteoarthritis has been changed by recent research.

126 s of the quadriceps as a clinical feature of knee osteoarthritis has been well recognized for some ti

127 Few new risk factors for progression of knee osteoarthritis have been identified in the past few

128 demiologic studies and systematic reviews of knee osteoarthritis have confirmed that being overweight

129 Among patients with knee osteoarthritis, high-intensity strength training co

130 78,169 controls), analyzing four phenotypes: knee osteoarthritis, hip osteoarthritis, knee and/or hip

131 s observed in the prevalence of radiographic knee osteoarthritis in FOA Study participants.

132 of knee osteoarthritis [PROOF (PRevention of knee Osteoarthritis in Overweight Females) study].

133 actors common to the development of hand and knee osteoarthritis in this non-elderly female populatio

134 Adverse outcomes in knee osteoarthritis include pain, loss of function, and

135 Symptomatic knee osteoarthritis increased but radiographic knee oste

136 Knee osteoarthritis is a common and increasing cause of

137 Knee osteoarthritis is a major cause of pain and functio

138 ates, but this may vary according to gender; knee osteoarthritis is more common in Chinese than U.S.

139 nvolvement of the quadriceps muscle group in knee osteoarthritis is receiving increasing research int

140 associated with reduced risk of radiographic knee osteoarthritis joint space narrowing progression in

141 Two hundred cases with radiographic knee osteoarthritis (Kellgren-Lawrence grades > or = 2)

142 ege of Rheumatology criteria for symptomatic knee osteoarthritis, Kellgren-Lawrence grades 2 or 3, we

143 een diabetes mellitus (diabetes) and risk of knee osteoarthritis (KOA) is confounded by high body mas

144 Knee osteoarthritis (KOA) is most common in the medial t

145 Knee osteoarthritis (KOA) is reported to have characteri

146 cerns about a lack of objectivity in grading knee osteoarthritis (KOA) on radiographs.

147 f quantitative thigh muscle MRI markers with knee osteoarthritis (KOA) outcomes are scarce.

148 oods and nutrients have been associated with knee osteoarthritis (KOA) progression, the association b

149 ce of osteoarthritis, prior studies indicate knee osteoarthritis may be more common in African-Americ

150 tween quadriceps strength and progression of knee osteoarthritis may differ according to these factor

151 Fifty-four older adults with hip or knee osteoarthritis (mean +/- SD age 75.3+/-7.1 years) p

152 n and women with advanced-stage, symptomatic knee osteoarthritis (OA) (n = 16).

153 to characterize dGEMRIC in the evaluation of knee osteoarthritis (OA) according to various radiograph

154 Biomechanical interventions for knee osteoarthritis (OA) aim to improve pain and retard

155 ip of knee malalignment to the occurrence of knee osteoarthritis (OA) among subjects without radiogra

156 Individuals with medial compartment knee osteoarthritis (OA) and genu varum use different mo

157 ted impact on patient function in studies of knee osteoarthritis (OA) and it is known that laxity inf

158 been documented as a feature of tibiofemoral knee osteoarthritis (OA) and may cause disease in this c

159 Knee osteoarthritis (OA) and pain are assumed to be barr

160 ssociations between radiographic features of knee osteoarthritis (OA) and pain have been demonstrated

161 herapists' use of exercise for patients with knee osteoarthritis (OA) and recent exercise recommendat

162 teoarthritis Initiative without radiographic knee osteoarthritis (OA) and without medial meniscal tea

163 Few risk factors for knee osteoarthritis (OA) are appreciated, and the discor

164 Fluctuations in pain in patients with knee osteoarthritis (OA) are common, but risk factors fo

165 ion and monitoring of individuals with early knee osteoarthritis (OA) are important considerations fo

166 py) is an emerging treatment for symptomatic knee osteoarthritis (OA) but its efficacy is uncertain.

167 women) of both radiographic and symptomatic knee osteoarthritis (OA) compared with that in the Frami

168 the effect of body weight on progression of knee osteoarthritis (OA) differs depending on the degree

169 Background The methods for assessing knee osteoarthritis (OA) do not provide enough comprehen

170 Individuals with medial knee osteoarthritis (OA) experience knee laxity and inst

171 ystem to grade subchondral bone attrition in knee osteoarthritis (OA) has low interobserver reliabili

172 ular treatment options for the management of knee osteoarthritis (OA) have been limited to analgesics

173 Patients with knee osteoarthritis (OA) have been shown to have somatos

174 raphic measures of the pathologic changes of knee osteoarthritis (OA) have shown modest associations

175 Previous studies of knee osteoarthritis (OA) have yielded variable estimates

176 recreational exercise on the development of knee osteoarthritis (OA) in a community-based cohort of

177 Knee Osteoarthritis (OA) is a common musculoskeletal dis

178 Knee osteoarthritis (OA) is a heterogeneous disease asso

179 Knee osteoarthritis (OA) is a leading cause of chronic d

180 Knee osteoarthritis (OA) is a leading cause of disabilit

181 Chronic musculoskeletal pain including knee osteoarthritis (OA) is a leading cause of disabilit

182 Knee osteoarthritis (OA) is believed to be highly preval

183 Progressive knee osteoarthritis (OA) is believed to result from loca

184 Knee osteoarthritis (OA) is highly prevalent and disabli

185 Knee osteoarthritis (OA) is highly prevalent, especially

186 tween knee pain and radiographic evidence of knee osteoarthritis (OA) is notoriously imperfect.

187 Symptomatic knee osteoarthritis (OA) is present in 1 in 8 patients a

188 e narrowing (JSN) over time in subjects with knee osteoarthritis (OA) is unknown.

189 Impairment of proprioception in knee osteoarthritis (OA) may contribute to, and/or resul

190 relative efficacy of available treatments of knee osteoarthritis (OA) must be determined for rational

191 the hypothesis that gait changes related to knee osteoarthritis (OA) of varied severity are associat

192 Subjects ages 50-79 years with knee osteoarthritis (OA) or at high risk of knee OA were

193 Chronic knee osteoarthritis (OA) pain patients (n = 56) underwen

194 with a 4-fold increase in the risk of medial knee osteoarthritis (OA) progression.

195 kground The exact contribution of statins to knee osteoarthritis (OA) radiographic outcomes and the c

196 Preventive strategies against knee osteoarthritis (OA) require a knowledge of risk fac

197 otential predictive tool for the severity of knee osteoarthritis (OA) symptoms and functional outcome

198 es during walking of individuals with medial knee osteoarthritis (OA) to determine the influence of q

199 Background At least 10% of all patients with knee osteoarthritis (OA) undergo treatment with injectab

200 ers ages 55-85 years with moderate to severe knee osteoarthritis (OA) were recruited.

201 (age, 45-55 years) and with risk factors for knee osteoarthritis (OA) were studied by using knee radi

202 Knee osteoarthritis (OA), a common cause of chronic pain

203 Knee osteoarthritis (OA), a disorder of cartilage and pe

204 ve quality of care for patients with hip and knee osteoarthritis (OA), a structured model for integra

205 (BMLs) are a known risk factor for incident knee osteoarthritis (OA), and deep learning (DL) methods

206 In a natural history study of symptomatic knee osteoarthritis (OA), both lateral view and fluorosc

207 e in studies of progression and treatment of knee osteoarthritis (OA), given the practical limitation

208 of the mechanisms and natural progression of knee osteoarthritis (OA), particularly in its early stag

209 In this cohort of subjects with knee osteoarthritis (OA), synovial fluid uric acid was s

210 In many patients with knee osteoarthritis (OA), the disease progresses, and th

211 nges in subchondral bone in murine models of knee osteoarthritis (OA), three key parameters, subchond

212 t least a moderately severe degree of hip or knee osteoarthritis (OA), we examined the effects of rac

213 y of individuals who have or are at risk for knee osteoarthritis (OA).

214 loading and contribute to the progression of knee osteoarthritis (OA).

215 served functional performance in adults with knee osteoarthritis (OA).

216 ge loss contributes to pain in patients with knee osteoarthritis (OA).

217 hic arthropathy but has not been assessed in knee osteoarthritis (OA).

218 estigated taping effects in individuals with knee osteoarthritis (OA).

219 r who have or are at high risk of developing knee osteoarthritis (OA).

220 as reduced knee pain in patients with medial knee osteoarthritis (OA).

221 iceps weakness is a risk factor for incident knee osteoarthritis (OA).

222 ta in a natural history study of symptomatic knee osteoarthritis (OA).

223 dy is a natural history study of symptomatic knee osteoarthritis (OA).

224 on of joint space narrowing in patients with knee osteoarthritis (OA).

225 ty in older overweight and obese adults with knee osteoarthritis (OA).

226 by age, back pain, and radiographic hip and knee osteoarthritis (OA).

227 treat musculoskeletal conditions, including knee osteoarthritis (OA).

228 romising orthobiologic treatment options for knee osteoarthritis (OA).

229 a leading risk factor for the development of knee osteoarthritis (OA).

230 of total knee replacement (TKR) for advanced knee osteoarthritis (OA).

231 ion is closely related to the progression of knee osteoarthritis (OA).

232 inal acupuncture treatments in patients with knee osteoarthritis (OA).

233 dergo knee replacement for the management of knee osteoarthritis (OA).

234 and human subjects, including patients with knee osteoarthritis (OA).

235 d Drug Administration-approved treatment for knee osteoarthritis (OA); however, its efficacy is contr

236 ections are frequently performed for hip and knee osteoarthritis (OA); however, there are conflicting

237 tics, disease burden (including radiographic knee osteoarthritis [OA]), self-reported disability, and

238 udies of subjects with high risk factors for knee osteoarthritis (obesity and anterior cruciate ligam

239 401 persons (mean age, 66.8 years) with knee osteoarthritis on radiography who were drawn from c

240 g appearances were observed in patients with knee osteoarthritis (on short-TE FSE, long-TE FSE, and S

241 udy that includes 4796 participants who have knee osteoarthritis or are at risk.

242 d as possible factors in the pathogenesis of knee osteoarthritis or as consequences of the disease.

243 tis (OR 1.36 [95% CI 1.00-1.84]; p < 0.049), knee osteoarthritis (OR 1.17 [95% CI 1.01-1.36]; p < 0.0

244 ity-adjusted life-years lost due to obesity, knee osteoarthritis, or both.

245 eficiency may be a risk factor for increased knee osteoarthritis pain in black Americans.

246 esponses to acupuncture treatment in chronic knee osteoarthritis pain patients (n = 45).

247 n D levels contribute to race differences in knee osteoarthritis pain.

248 flammatory activities suggest rethinking the knee osteoarthritis paradigm.

249 fied methodologic challenges to the study of knee osteoarthritis, particularly osteoarthritis progres

250 ferentiate phenotypes within a heterogeneous knee osteoarthritis population.

251 ception of malalignment, no risk factors for knee osteoarthritis progression have been identified.

252 omized controlled trial on the prevention of knee osteoarthritis [PROOF (PRevention of knee Osteoarth

253 Arthroscopic assessment of patients with knee osteoarthritis refractory to traditional therapy su

254 e of lateral wedges and lower pain in medial knee osteoarthritis, restriction of studies to those usi

255 ymptomatic patients with a meniscal tear and knee osteoarthritis results in better functional outcome

256 o determine the impact of early radiographic knee osteoarthritis (ROA) and ROA risk factors on femoro

257 Using data from two long-term knee osteoarthritis studies OAI and CHECK, we tested mul

258 Participants of the Framingham Knee Osteoarthritis Study were examined with a 1.5T MRI

259 Participants completed a questionnaire on knee osteoarthritis symptoms and underwent quantitative

260 in STEP-KOA reported modest improvements in knee osteoarthritis symptoms compared with the control g

261 riatic osteoarthritis, rheumatoid arthritis, knee osteoarthritis, systolic blood pressure, diastolic

262 eductions in body weight and pain related to knee osteoarthritis than placebo.

263 lid alternative for the treatment of chronic knee osteoarthritis that is more logistically convenient

264 r total WOMAC score in patients with hip and knee osteoarthritis, the absolute MCID is 7 U (95% CI, 4

265 g participants with symptomatic radiographic knee osteoarthritis, the intra-articular administration

266 Across six primary human knee osteoarthritis tissues, miR-126-3p is highest in su

267 s ranged from 1.857 in nonobese persons with knee osteoarthritis to 3.501 for persons affected by bot

268 nfluence the responsiveness of patients with knee osteoarthritis to exercise and physical activity pr

269 rognostic biomarkers may be used in clinical knee osteoarthritis to identify subgroups in whom the di

270 l that captures the long-term progression of knee osteoarthritis to longitudinally assess pain-relate

271 uence the responsiveness of individuals with knee osteoarthritis to physical therapy.

272 omly assigned 1583 patients with symptomatic knee osteoarthritis to receive 1500 mg of glucosamine da

273 performance in predicting the progression of knee osteoarthritis to total knee replacement using MRI

274 joint space narrowing (JSN) in patients with knee osteoarthritis treated with doxycycline.

275 rvational cohort data from the Vitamin D for Knee Osteoarthritis trial.

276 this research, we enrolled 40 patients with knee osteoarthritis undergoing total knee replacement in

277 Twelve patients with knee osteoarthritis underwent dGEMRIC and T1rho mapping

278 e find circulating miR-126-3p is elevated in knee osteoarthritis versus controls.

279 In patients with knee osteoarthritis, viscosupplementation is associated

280 Conclusion Knee osteoarthritis was associated with longitudinal MRI

281 Whereas once knee osteoarthritis was considered a 'wear-and-tear' con

282 Knee osteoarthritis was determined by Kellgren-Lawrence

283 wever a new measure for Japanese people with knee osteoarthritis was developed based on these constru

284 nity-dwelling older women (>/=70 years) with knee osteoarthritis was examined through self report, pr

285 Radiographic knee osteoarthritis was inversely associated with serum

286 th a radiographically confirmed diagnosis of knee osteoarthritis were evaluated from the clinical tri

287 of progression of radiographic-demonstrated knee osteoarthritis were noted between both treatments.

288 ho had undergone primary, unilateral TKA for knee osteoarthritis were randomized to 1 of 2 interventi

289 men and women with radiographic evidence of knee osteoarthritis were randomly assigned to four 18-mo

290 ) with symptomatic, radiologically confirmed knee osteoarthritis were recruited between April 20, 201

291 Eligible participants had unilateral knee osteoarthritis, were contemplating TKA, and had pre

292 tilage sGAG content in vivo in patients with knee osteoarthritis, whereas T1rho mapping does not appe

293 Patients with medial compartment knee osteoarthritis who have a visible varus thrust will

294 nrolled 100 patients with moderate-to-severe knee osteoarthritis who were eligible for unilateral tot

295 In patients with knee osteoarthritis who were eligible for unilateral tot

296 The adjusted association of knee osteoarthritis with all-cause mortality in the MOA

297 The conventional approach to treating knee osteoarthritis with analgesics and physical therapy

298 Among participants with obesity and knee osteoarthritis with moderate-to-severe pain, treatm

299 ular triamcinolone vs saline for symptomatic knee osteoarthritis with ultrasonic features of synoviti

300 aining, have been examined as treatments for knee osteoarthritis, with considerable variability in th