ライフサイエンスコーパス: knee pain

1 ly associated with the new onset of frequent knee pain.

2 followed by regional (14%) or diffuse (10%) knee pain.

3 ncreasing number of people suffering chronic knee pain.

4 ted hallux valgus, nodal osteoarthritis, and knee pain.

5 es a clinically meaningful change in chronic knee pain.

6 me in middle-aged and older individuals with knee pain.

7 ML score is predictive of the development of knee pain.

8 ether enlarging BMLs are associated with new knee pain.

9 ects were again queried twice about frequent knee pain.

10 mproving functioning in persons with chronic knee pain.

11 ographic osteoarthritis in older adults with knee pain.

12 chair-stand time, and use of medications for knee pain.

13 distinguished by the presence or absence of knee pain.

14 herence or changes in quadriceps strength or knee pain.

15 ogy accounted for only 1 in 11 patients with knee pain.

16 volume loss and no significant difference in knee pain.

17 subgroup of patients with moderate-to-severe knee pain.

18 hed controls and tested for association with knee pain.

19 anagement and treatment of older people with knee pain.

20 is at baseline nor followup, and no baseline knee pain.

21 persons aged 50 years or older with chronic knee pain.

22 functional declines among older adults with knee pain.

23 months on progression of cartilage loss and knee pain.

24 ributes to the development of future chronic knee pain.

25 e prescription for older adults with chronic knee pain.

26 of blacks and 31% of whites reported hip or knee pain.

27 people with self-reported symptoms of hip or knee pain.

28 adults 65 years of age or older with chronic knee pain.

29 is debate about benefits of acupuncture for knee pain.

30 ructural and nonstructural factors influence knee pain.

31 classified by radiography and by severity of knee pain.

32 these structural lesions and the severity of knee pain.

33 th a body mass index of 18-27 kg/m(2) and no knee pain.

34 djustment for age, sex, body mass index, and knee pain.

35 knee pain than those without DM and without knee pain.

36 for conditions such as chronic low back and knee pain.

37 ound between the effusion score and frequent knee pain.

38 moderate/severe knee pain and those with no knee pain, 12.9% and 10.9% of men (P=0.74) and 6.7% and

39 t knee pain and longitudinally with frequent knee pain 2 years after the baseline evaluation.

40 For 177 subjects with chronic knee pain, 3T magnetic resonance imaging (MRI) of both k

41 luded the WOMAC disability subscale, overall knee pain, 50-feet walk time, chair-stand time, and use

42 s experienced joint-specific improvements in knee pain (77.1% [95% CI, 73.5%-80.7%]) and in hip funct

43 ngaging their provider in a discussion about knee pain (92% versus 85%), to receive a referral to an

44 50 years or older with chronic and frequent knee pain, a Western Ontario McMaster Universities Osteo

45 use was also associated with a reduction in knee pain according to the WOMAC scores.

46 sked twice at baseline about the presence of knee pain, aching, or stiffness (classified as frequent

47 (range 0-3) and the development of frequent knee pain, aching, or stiffness (odds ratio [OR] 1.21, 9

48 niscal damage on the development of frequent knee pain, aching, or stiffness in middle-aged and older

49 of a meniscal tear was 63% among those with knee pain, aching, or stiffness on most days and 60% amo

50 hritis (adjusted OR 1.66; 95% CI 1.26-2.17), knee pain (adjusted OR 1.96; 95% CI 1.65-2.32), big toe

51 rfaces was associated with frequent incident knee pain (adjusted OR 4.19, 95% CI 1.56-11.22).

52 ores indicating more severe symptoms) and in knee pain after exercise (rated on a scale from 0 to 10,

53 points; 95% CI, -9.2 to 4.1); and score for knee pain after exercise, 3.1 and 3.3 points, respective

54 hundred twenty subjects from the OAI without knee pain (age, 45-55 years) and with risk factors for k

55 nd disability were less severe in those with knee pain alone than in those with knee pain and pain el

56 elihood of patient-provider discussion about knee pain and access to surgical evaluation.

57 epidemiologic studies of knee pain, frequent knee pain and activity-related pain severity are the mos

58 se with greater quadriceps strength had less knee pain and better physical function over followup (P<

59 th greater quadriceps strength also had less knee pain and better physical function over followup.

60 Knee pain and disability were less severe in those with

61 Few data exist on the association between knee pain and fracture.

62 the FOA Study, participants were asked about knee pain and had bilateral weight-bearing anteroposteri

63 Both knee pain and hip pain participants expressed similar pa

64 ustering was also associated with persistent knee pain and impaired physical functioning.

65 They were also asked about knee pain and limitations in function by using the Short

66 ith moderate-to-severe knee pain or frequent knee pain and longitudinally with frequent knee pain 2 y

67 ignificantly more common among subjects with knee pain and may contribute to pain in these individual

68 Knee pain and mobility were assessed with standard tests

69 no knee pain, and in 0% of the group with no knee pain and no ROA (P = 0.004).

70 ery 6 months thereafter in 115 patients with knee pain and OA of mainly the tibiofemoral joint.

71 Knee pain and OA should be regarded as independent risk

72 For anterior knee pain and OA, medially-directed tape decreased pain

73 Patients completed a questionnaire about knee pain and OA.

74 ody mass index (BMI)-adjusted prevalences of knee pain and osteoarthritis at later examinations were

75 nce for the effectiveness of acupuncture for knee pain and other common treatments, including exercis

76 hose with knee pain alone than in those with knee pain and pain elsewhere, even after adjusting for a

77 Similar associations were seen with knee pain and physical functioning measures.

78 of antiresorptive drugs and the presence of knee pain and radiographic changes of OA of the knee.

79 The relationship between knee pain and radiographic evidence of knee osteoarthrit

80 ians and researchers is that the severity of knee pain and related disability is worse in the presenc

81 ) were present in 12.1% of the patients with knee pain and ROA, in 20.5% of the patients with ROA and

82 (BMLs), synovitis, and effusion to frequent knee pain and severity of knee pain was examined using c

83 lay an important role in the pathogenesis of knee pain and should be studied further.

84 Secondary outcomes were knee pain and stiffness (WOMAC), average pain (NRS), int

85 The sixth patient presented with knee pain and swelling.

86 udy, the age- and BMI-adjusted prevalence of knee pain and symptomatic knee osteoarthritis approximat

87 to 25% decrease in the prevalence ratios for knee pain and symptomatic knee osteoarthritis.

88 that intravenous zoledronic acid may reduce knee pain and the size of bone marrow lesions in people

89 Similarly, for those with moderate/severe knee pain and those with no knee pain, 12.9% and 10.9% o

90 sions are equally common among subjects with knee pain and those without knee pain, other periarticul

91 kling, even after adjustment for severity of knee pain and weakness.

92 Subjects were then asked about knee pain and weight-bearing anteroposterior and lateral

93 ndependently associated with the presence of knee pain and with quadriceps weakness.

94 bracing effects in individuals with anterior knee pain, and 3 investigated taping effects in individu

95 OA, in 20.5% of the patients with ROA and no knee pain, and in 0% of subjects with neither ROA nor kn

96 in, in only 3.9% of patients with ROA but no knee pain, and in 0% of the group with no knee pain and

97 explore the association between knee height, knee pain, and knee OA.

98 in states: arthritic knee pain, experimental knee pain, and pain-free.

99 History of knee pain, and socio-demographic, laboratory, and clinic

100 cipants could identify the location of their knee pain, and trained interviewers could reliably recor

101 nce of radiographic knee OA, and severity of knee pain, and were randomized to strength training (ST)

102 oft tissue arthritic changes associated with knee pain are comparable between hemiplegic and non-hemi

103 trogen, was associated with less severity of knee pain as assessed by WOMAC scores.

104 knees," in which the patient rated standing knee pain as severe or extreme after the washout and in

105 ied secondary outcomes, including changes in knee pain assessed by a visual analog scale (-11.5 in th

106 especified secondary outcomes were change in knee pain assessed by a visual analog scale (0 [no pain]

107 [95% CI, -2.3 to 12.8]; P = .17), changes in knee pain assessed by the Western Ontario and McMaster U

108 Efficacy was measured using self-reported knee pain at 2 years.

109 The primary outcome was knee pain at 24 weeks of follow-up assessed with the Wes

110 Data on self-reported knee pain at 4 time points over 12 years were analyzed i

111 A case knee was defined as absence of knee pain at baseline but presence of knee pain both tim

112 inal analyses (in 168 knees without frequent knee pain at baseline) revealed that percent denuded bon

113 years, with few women consistently reporting knee pain at each time point.

114 Change in self-reported knee pain at follow-up.

115 s but who subsequently developed new chronic knee pain at followup.

116 bjects who reported a > or = 20% increase in knee pain at the majority of their followup visits had m

117 nalysis and identified those who reported no knee pain at the time of motion analysis but who subsequ

118 osteoarthritis such as nodal osteoarthritis, knee pain, big toe pain, and self-reported osteoarthriti

119 sex, body mass index, nodal osteoarthritis, knee pain, big toe pain, joint replacement, self-reporte

120 nce of knee pain at baseline but presence of knee pain both times at followup.

121 associated with the presence and severity of knee pain but not with the presence of radiographic OA.

122 netic resonance imaging (MRI) are related to knee pain, but no longitudinal studies have been done.

123 or without pain elsewhere, or other pain (no knee pain, but pain elsewhere).

124 e therapy is associated with improvements in knee pain, but the cost of delivering the exercise progr

125 ignificantly better than placebo in reducing knee pain by 20 percent.

126 steoarthritis Study were queried about their knee pain by interview, and knees were assessed by magne

127 and osteoarthritis outcome score (KOOS) and knee pain by visual analogue score (VAS).

128 To investigate the links between knee pain characteristics and restricted mobility outsid

129 ected force on the patella decreased chronic knee pain compared with no tape by 16.1 mm (95% confiden

130 d radiographic features were associated with knee pain, confirming that structural abnormalities in t

131 ciation between structural abnormalities and knee pain, contrary to the 'so-called' structure-symptom

132 Knee pain decreased in both groups by a mean -2.31 (95%

133 At followup, 7 had developed new chronic knee pain defined as pain or stiffness on most days of t

134 ual primary care and participation in ESCAPE-knee pain delivered to individuals (Indiv-rehab) or grou

135 nd to explore the association between DM and knee pain distribution (unilateral or bilateral versus n

136 r pain severity and unilateral and bilateral knee pain distribution.

137 ne was approved for the treatment of chronic knee pain due to osteoarthritis and has been conditional

138 Sixty consecutive patients with knee pain due to various arthritides had a clinical exam

139 Adults age >or=65 years with chronic knee pain experience significant declines in balance and

140 ed during 3 different pain states: arthritic knee pain, experimental knee pain, and pain-free.

141 People with knee pain focused on stairs, weight, and stiffness, whil

142 Participants age >/=50 years, reporting knee pain for >6 months, were recruited from 54 inner-ci

143 The 250 patients had low back, hip, or knee pain for 3 months or longer and at least moderate d

144 rioceptive acuity in quartiles with baseline knee pain (frequent pain yes/no), WOMAC pain score, self

145 In longitudinal epidemiologic studies of knee pain, frequent knee pain and activity-related pain

146 outcome measure was a 20 percent decrease in knee pain from baseline to week 24.

147 Among participants with knee pain from osteoarthritis, use of biomechanical foot

148 their efficacy and safety as a treatment for knee pain from osteoarthritis.

149 ional covariates (age, sex, body mass index, knee pain), general bone mineral content, and joint spac

150 Knee pain global severity was associated with symptom di

151 and with anxiety and depression both in the knee-pain group and in the other-pain group (association

152 ain group (associations were stronger in the knee-pain group).

153 knee pain, those who did develop new chronic knee pain had higher baseline adduction moments for all

154 Patients with hip or knee pain had mean +/- SD Western Ontario and McMaster U

155 Patients with knee pain had more severe radiographic disease than did

156 Fifty-seven percent of responders with knee pain had pain in at least 2 other joint areas.

157 Provision of ESCAPE-knee pain had small cost implications, but it was more l

158 Results suggest that the prevalence of knee pain has increased substantially over 20 years, ind

159 ith a clinical diagnosis of knee OA and with knee pain have an increased risk of nonvertebral and hip

160 Novel approaches to the study of knee pain have demonstrated a strong association between

161 Most people with knee pain have multiple joint site pain.

162 Among women with knee pain, higher knee height was associated with more s

163 us tendinosis had greater risk of hemiplegic knee pain (HKP) when compared to stroke patients without

164 We describe commonly used measures of knee pain in longitudinal studies and review various ana

165 ne plate exposure and prevalent and incident knee pain in patients with knee OA.

166 ynovitis are associated with fluctuations in knee pain in patients with knee OA.

167 ing tibial cartilage loss or improving WOMAC knee pain in patients with knee osteoarthritis.

168 studies, a lateral-wedge insole has reduced knee pain in patients with medial knee osteoarthritis (O

169 sociation between diabetes mellitus (DM) and knee pain in people with osteoarthritis (OA).

170 The risk of knee pain in stroke is higher in the presence of pes ans

171 Given the magnitude of changes in knee pain in the active treatment group, heat retention

172 arthritis Initiative Clinical Center who had knee pain in the last 12 months were studied.

173 esent in 14.9% of patients with both ROA and knee pain, in only 3.9% of patients with ROA but no knee

174 When the differential diagnosis for acute knee pain includes an exacerbation of osteoarthritis, cl

175 Age- and BMI-adjusted prevalence of knee pain increased by about 65% in NHANES from 1974 to

176 fined knee osteoarthritis, and self-reported knee pain information from a cross-sectional, community-

177 isk factors were age, body mass index (BMI), knee pain intensity (on a visual analog scale [VAS]), lo

178 4), BMI (OR 1.26/5 units, 95% CI 1.01-1.57), knee pain intensity (OR 1.21/20 mm on VAS, 95% CI 1.00-1

179 utcome over 3 years, adjusting for age, BMI, knee pain intensity, disease severity, and additional po

180 ceptive inaccuracy, as well as age, BMI, and knee pain intensity.

181 verage pain (NRS), intermittent and constant knee pain (Intermittent and Constant Osteoarthritis Pain

182 For persons with chronic knee pain, Internet-delivered, physiotherapist-prescribe

183 and/or cardiac disease, extremity fracture, knee pain, intraabdominal malignancy, and stroke.

184 Chronic knee pain is a major cause of disability and health care

185 Development of knee pain is associated with an increase in BMLs as reve

186 Knee pain is frequently seen in patients of all ages, wi

187 health factors (OA severity, knee symptoms, knee pain, knee injury, body mass index, comorbidity, de

188 h knee OA, radiographic severity of knee OA, knee pain, knee motion, and quadriceps strength were als

189 on of osteoarthritis (OA) is that changes in knee pain may affect extension, thereby altering the app

190 f participants with radiographic knee OA and knee pain met recommended physical activity levels.

191 was stratified according to the severity of knee pain (mild [N=1229] vs. moderate to severe [N=354])

192 In persons with unilateral knee pain, MRI and radiographic features were associated

193 ain (n = 51), and those with neither ROA nor knee pain (n = 24).

194 groups: those with radiographic OA (ROA) and knee pain (n = 376), those with ROA and no knee pain (n

195 d knee pain (n = 376), those with ROA and no knee pain (n = 51), and those with neither ROA nor knee

196 OA patients had knee pain, needed 67% more time to complete 4 functional

197 han 50 years with moderate or severe chronic knee pain, neither laser nor needle acupuncture conferre

198 ery had helped someone they knew with hip or knee pain (not significant).

199 Primary outcomes were average knee pain (numeric rating scale, 0 [no pain] to 10 [wors

200 ed pain in individuals ages 45-65 years with knee pain, OA, and meniscal tears.

201 dertaken to examine the effect of changes in knee pain of varying magnitudes on radiographic joint sp

202 The evaluation of acute knee pain often includes radiography of the knee.

203 cial treatments are needed to manage chronic knee pain on a population level.

204 aching, or stiffness (classified as frequent knee pain) on most days; absence of knee pain was the ba

205 , when compared with placebo, did not reduce knee pain or cartilage volume loss in patients with symp

206 risk factor of interest on change in risk of knee pain or change in pain severity.

207 d bone is associated with moderate-to-severe knee pain or frequent knee pain and longitudinally with

208 rs, body mass index of 19-27 kg/m(2), and no knee pain or OA on radiographs at baseline.

209 Those with knee pain or other pain were subdivided by the extent of

210 ure was associated with knee OA but not with knee pain or physical functioning.

211 than 40 years were recruited irrespective of knee pain or radiographic osteoarthritis.

212 -1.47), and baseline to 18-month increase in knee pain (OR 1.32/20 mm on VAS, 95% CI 1.06-1.65).

213 the source population in terms of age, sex, knee pain, osteoarthritis, and rheumatoid arthritis.

214 ng subjects with knee pain and those without knee pain, other periarticular lesions (including bursit

215 d knowing someone who had surgery for hip or knee pain (P < 0.0001).

216 (P < 0.05), stair-climb time (P < 0.05), and knee pain (P < 0.05) relative to the healthy lifestyle g

217 knee height was associated with more severe knee pain (P = 0.0004 for the highest quartile versus th

218 , and in 0% of subjects with neither ROA nor knee pain (P = 0.116).

219 ze of BMLs was associated with resolution of knee pain (P for trend = 0.007).

220 ies are needed to determine whether specific knee pain patterns correlate with discrete pathologic fi

221 s assessed and recorded participant-reported knee pain patterns into 8 local areas, 4 regional areas,

222 on the basis of self-completed questions on knee pain persistence and global severity (Chronic Pain

223 wer independent associations were found with knee pain persistence.

224 imary knee OA, independent of sex, age, BMI, knee pain, physical activity, and disease severity.

225 justing for sex, age, body mass index (BMI), knee pain, physical activity, cohort, and disease severi

226 Knee pain prevalence and a clinician diagnosis of knee O

227 Arthritic Knee Pain through Exercise (ESCAPE-knee pain) program.

228 ESCAPE-knee pain provides a safe, relatively brief intervention

229 Secondary outcomes were knee pain, quality of life, global change (overall, pain

230 with a body mass index of > or =28 kg/m(2), knee pain, radiographic evidence of knee OA, and self-re

231 contributions from other impairments such as knee pain, range of motion, and quadriceps strength.

232 and a knee pain scale to measure obesity and knee pain, respectively.

233 d dorsiflexion, and 3) body mass index and a knee pain scale to measure obesity and knee pain, respec

234 RI-measured tibial cartilage volume or WOMAC knee pain score over 2 years.

235 s were constructed by dichotomizing clinical knee pain scores (median split) and knee OA grade scores

236 iscal damage and the development of frequent knee pain seems to be present because both pain and meni

237 Primary outcomes were knee pain severity (Western Ontario and McMaster Univers

238 was significantly associated with increased knee pain severity over 7 days (B 0.68; 95% CI 0.25-1.11

239 nee symptoms were assessed by interview, and knee pain severity was evaluated using the Western Ontar

240 Knee pain severity was strongly associated with restrict

241 at examining the association between DM and knee pain severity, and to explore the association betwe

242 l contributions from selected comorbidities, knee pain severity, limitation in walking, and specific

243 fter adjustment for age, sex, walking speed, knee pain severity, physical activity, varus malalignmen

244 adjusted for age, sex, body mass index, and knee pain severity.

245 ns with obesity, associations between JH and knee pain showed higher ORs in obese participants (OR 11

246 en symptomatic, chondral lesions manifest in knee pain, swelling, and loss of function.

247 ikelihood of having unilateral and bilateral knee pain than those without DM and without knee pain.

248 e who have had surgical treatment of hip and knee pain than whites and appear to be less likely to pe

249 e, relatively brief intervention for chronic knee pain that is equally effective whether delivered to

250 rheumatology clinic for bilateral wrist and knee pain that was unresponsive to physiotherapy and int

251 Knee pain, the primary outcome, was assessed by the WOMA

252 rity of community-dwelling older adults with knee pain this method enables the presence of radiograph

253 ne or more of these locations in people with knee pain.This review does not cover psychological aspec

254 Compared with those who did not develop knee pain, those who did develop new chronic knee pain h

255 ng Self-Management and Coping with Arthritic Knee Pain through Exercise (ESCAPE-knee pain) program.

256 ng Self-management and Coping with Arthritic Knee Pain through Exercise [ESCAPE-knee pain]) with usua

257 progressive knee osteoarthritis and related knee pain to identify targets for primary and secondary

258 Twelve patients with chronic knee pain unresponsive to conservative treatments and ra

259 We randomized 30 patients with chronic knee pain unresponsive to conservative treatments and sh

260 nd (b) "nonflaring knees," in which standing knee pain was absent, mild, or moderate after the washou

261 Knee pain was assessed by using the Western Ontario and

262 At baseline and at followup visits, knee pain was assessed using a visual analog scale, and

263 Increasing severity of knee pain was associated with a greater risk of falls an

264 Prevalent knee pain was associated with an increased risk of falls

265 mined whether the development of new chronic knee pain was associated with higher peak adduction mome

266 al analyses revealed that moderate-to-severe knee pain was associated with percent denuded bone in th

267 Frequent knee pain was associated with percent denuded bone in th

268 Moderate-to-severe knee pain was defined as a score of >or=40 mm on a knee-

269 fic 100-mm visual analog scale, and frequent knee pain was defined as pain on most days during the pa

270 d isometrically for each leg separately, and knee pain was evaluated by questionnaire.

271 Knee pain was evaluated using a visual analog scale scor

272 fusion to frequent knee pain and severity of knee pain was examined using conditional logistic regres

273 in the temporal fluctuation of self-reported knee pain was seen in this community-based prospective s

274 ren-Lawrence score from radiography, whereas knee pain was self-reported.

275 In conditional logistic analyses, knee pain was significantly associated with both radiogr

276 Baseline knee pain was slightly worse in the treatment group (mea

277 frequent knee pain) on most days; absence of knee pain was the baseline eligibility criterion.

278 e (the more symptomatic one in subjects with knee pain) was imaged with a 1.5T scanner using T1- and

279 c visits, the odds ratios (ORs) for frequent knee pain were 1.2, 1.2, 1.5, 2.2, 2.4, and 2.5, respect

280 ears), prevalences of knee OA and persistent knee pain were 11% and 30%, respectively.

281 ported that they currently had either hip or knee pain were recruited from the UK Somerset and Avon S

282 atellar taping or bracing effects on chronic knee pain were sourced from 7 electronic databases (to N

283 (282 patients aged >/=50 years with chronic knee pain) were treated by family physician acupuncturis

284 cts ages 45 years and older, with or without knee pain, were recruited from Veterans Affairs medical

285 the observed heterogeneity of self-reported knee pain when pain status is measured at only one time

286 The primary efficacy measures were knee pain while walking and the patient's global assessm

287 ugh 16, the mean reductions from baseline in knee pain while walking ranged from 45 to 62% with vario

288 of people with and those without knee OA and knee pain who meet recommended physical activity levels

289 individuals ages 70-79 years with unilateral knee pain who were enrolled in the Health, Aging, and Bo

290 nty-five films from individuals with chronic knee pain who were not awaiting TKR and 75 films from as

291 in 9% of films from individuals with chronic knee pain who were not awaiting TKR, and in 1% of films

292 s were men and women (ages 70-79 years) with knee pain who were participating in the Health, Aging, a

293 cordance, as well as between fluctuations of knee pain with changes in specific structural lesions.

294 We examined the association of knee OA and knee pain with fracture and falls in elderly men and wom

295 sponders were categorized as having no pain, knee pain with or without pain elsewhere, or other pain

296 lso assessed were whether patients discussed knee pain with their primary care provider or saw an ort

297 f words uttered by participants experiencing knee pain with words used by participants experiencing h

298 ed an underlying biomedical model of care of knee pain, with knee OA viewed as a progressive degenera

299 Arthritic Knee Pain through Exercise [ESCAPE-knee pain]) with usual primary care in improving functio

300 olving 695 adults ages >/=50 years reporting knee pain within the last year identified by postal surv

301 th 3 general practices and were experiencing knee pain within the previous 6 months attended research