ライフサイエンスコーパス: lactate

1 rom changes in pH or in the concentration of lactate.

2 ctra regarding their pH and concentration of lactate.

3 d a more efficient conversion of pyruvate to lactate.

4 triple Tn mutant that cannot produce D- or L-lactate.

5 d glucose uptake and incomplete oxidation to lactate.

6 developed a dependence on glycolytic flux to lactate.

7 robic glycolysis generating large amounts of lactate.

8 tatic function for the glycolytic metabolite lactate.

9 alpha (hypoxia-inducible factor-1alpha), and lactate.

10 ng metabolized through intermediates such as lactate.

11 ed increased flux of glucose metabolism into lactate.

12 management strategy in persons with high CSF lactate.

13 their energy via the breakdown of glucose to lactate.

14 . limosum cells grown on l-carnitine than on lactate.

15 o promote tumor growth by tumor cell-derived lactate.

16 (2+) dynamics is selectively stimulated by L-lactate.

17 antly less phosphorylated glucose and little lactate.

18 haracterizing novel solid forms of calcium l-lactate.

19 ication driven by L. plantarum production of lactate.

20 o and representative of the concentration of lactate.

21 83-179) vs 73 mg/L (IQR: 12-98), P < 0.01), lactate [1.1 mmol/L (IQR: 1.0-1.6) vs 4.6 mmol/L (IQR: 2

22 uals with mid-range (22%; 25/112) or low CSF lactate (9%; 9/97; p=<.0001).

23 production from a mixed substrate (lactose, lactate, acetate, and ethanol).

24 ese findings suggest that tumor cell-derived lactate activates GPR81 in dendritic cells and prevents

25 ntrations of hexose monophosphate, pyruvate, lactate, alanine, glycerol-3 phosphate, and isocitrate w

26 n LECs, yet activation was not stimulated by lactate alone.

27 C and OMS, respectively, compared to acetate/lactate-amended setups (6.3 +/- 0.7 mug As/L).

28 .026 y(-1) for unamended and 0.035 y(-1) for lactate-amended) were obtained based on (13)C enrichment

29 ing uncontaminated groundwater, unamended or lactate-amended, in a chamber above a TCE-infused sandst

30 Calcium l-lactate, an organic salt derived from l-lactic acid, is

31 cose, and limit of detections of 0.41 mM for lactate and 0.057 mM for glucose.

32 the detected linear ranges of 0.5-20 mM for lactate and 0.1-5 mM for glucose, sensitivities of 4.1 n

33 ate and its downstream metabolites, 1-(13) C-lactate and 1-(13) C-alanine, predicted histological via

34 lucose, sensitivities of 4.1 nA/mM.mm(2) for lactate and 56 nA/mM.mm(2) for glucose, and limit of det

35 ne, and subsequently metabolized to [1-(13)C]lactate and [(13)C]bicarbonate.

36 Baseline lactate and alanine were associated with baseline and 1-

37 Lactate and catecholamine clearance were also significan

38 A simultaneous lactate and glucose monitoring system was constructed us

39 e sensors achieved simultaneous detection of lactate and glucose without cross-talking error, with th

40 idge oscillator for the fused measurement to lactate and glucose.

41 ents with PJI contains elevated amounts of D-lactate and IL-10 compared with control subjects, and ba

42 onstitutive mRNA translation rate, decreases lactate and key glycolytic and tricarboxylic acid (TCA)

43 ange during hypoxic exercise but had greater lactate and lower pH than controls for all exercise bout

44 eatment effects were also detected for blood lactate and minimum oxygen uptake rate; although, these

45 was metabolized primarily by LDH to generate lactate and NAD(+) and by SpxB and PDHc to generate acet

46 r: both are hypoxic, show elevated levels of lactate and other metabolic by-products and have low lev

47 s been focused on systems to measure sweat l-lactate and other metabolites, where the employment of t

48 The levels of lactate and other molecules were significantly lower in

49 catalase (CAT), which irreversibly converts lactate and oxygen to pyruvate and water.

50 Thereby they produce significant amounts of lactate and protons, which are exported via monocarboxyl

51 Hip fracture patients showed elevated CSF lactate and pyruvate during delirium, consistent with ac

52 atio between the cytosolic concentrations of lactate and pyruvate is a direct readout of the balance

53 The sensitivity of the indicator to lactate and pyruvate was characterized through changes i

54 ablishing a mechanism by which AHR regulates lactate and UMP production in MYC-overexpressing cells.

55 A total of 26 volatiles were present in lactating and gestating sow faeces.

56 short chain fatty acids (mainly acetate and lactate) and favoring growth of the beneficial genera Bi

57 icarbonate), lactate dehydrogenase ([1-(13)C]lactate), and alanine transaminase ([1-(13)C]alanine) wa

58 line, phosphocholine, N-acetylcarbohydrates, lactate, and B-hydroxybutyrate could be considered as pu

59 otropes, and association with cardiac index, lactate, and central venous oxygen saturation.

60 transferase, lactate dehydrogenase, glucose, lactate, and pH) with graft features and outcome.

61 n a diet of salivary factors including urea, lactate, and salivary protein degradation.

62 Individuals with an elevated baseline CSF lactate are more likely to present with altered mental s

63 NMR spectroscopy revealed changes in tumor lactate as a potential early biomarker for IL17/PD-1 com

64 ch white matter of the brain rely heavily on lactate as a substrate for ATP synthesis.

65 pause, females are continuously pregnant and lactating at the same time throughout their reproductive

66 ly metastasizing melanomas, with circulating lactate being a more prominent source of tumour lactate

67 s no significant difference in the levels of lactate between db/db and control mouse retina.

68 associated increase in flux from pyruvate to lactate catalyzed by lactate dehydrogenase using hyperpo

69 nfiltrating T cells by siRNA-loaded chitosan-lactate (CL) nanoparticles to facilitate priming anti- t

70 This caused complete lactate clearance despite decreased OCC.

71 assessed by viability criteria based on the lactate clearance to levels <=2.5 mmol/L within 4 h.

72 rman, the AT coalesced the increase of blood lactate concentration ([La(-) ]), during a progressive e

73 c profiles, including significant changes in lactate concentration in breast cancer co-culture.

74 ith less dynamic hyperinflation, lower blood lactate concentration, and greater respiratory and locom

75 Severe anaemia, elevated lactate concentration, respiratory distress, and parasit

76 The sensor displays lactate concentrations in the range of 0-10 mM over the

77 .014 and p = 0.0002, respectively) and blood lactate concentrations were lower (4.9 +/- 2.4 mmol l(-1

78 hyperpolarized [1-(13)C]pyruvate-to-[1-(13)C]lactate conversion rates as well as global conversion we

79 hyperpolarized [1-(13)C]pyruvate-to-[1-(13)C]lactate conversion rates in aggressive tumors to enhance

80 e influxes and [1-(13)C]pyruvate-to-[1-(13)C]lactate conversion rates, independent of glycolysis or L

81 hyperpolarized [1-(13)C]pyruvate-to-[1-(13)C]lactate conversion was highly dependent on and criticall

82 All PP except lactate correlated with EAD, 90-minute alanine aminotran

83 The data suggest CD4(+) T cells from lactating cows have an altered metabolic responsiveness

84 Dietary intake in early lactating cows is outmatched by milk production.

85 We hypothesize that oocytes from lactating cows undergoing transient metabolic stress exh

86 cells from dry cows than CD4(+) T cells from lactating cows.

87 respiratory rate; elevated levels of venous lactate, creatinine, or procalcitonin; or low platelet o

88 illonella, a commensal microbe known to have lactate-degrading and performance-enhancing properties,

89 eatment, beta-2 microglobulin >= 5 mg/L, and lactate dehydrogenase > 250 U/L.

90 pyruvate dehydrogenase, [(13)C]bicarbonate), lactate dehydrogenase ([1-(13)C]lactate), and alanine tr

91 aspartate transaminase (P = .0040); elevated lactate dehydrogenase (LDH) (P < .0001); and increased p

92 Lactate dehydrogenase (LDH) accounts for the fermentativ

93 Cell viability, cell number, lactate dehydrogenase (LDH) activity, cell necrosis, tra

94 as of sufficient magnitude to increase serum lactate dehydrogenase (LDH) and was oxidative in nature

95 ime points using fluorescence microscopy and Lactate dehydrogenase (LDH) assay on the supernatant.

96 Lactate dehydrogenase (LDH) catalyzes the conversion of

97 High IL-6 level, C-reactive protein level, lactate dehydrogenase (LDH) level, ferritin level, d-dim

98 ehyde-3-phosphate dehydrogenase (GAPDH) to L-lactate Dehydrogenase (LDH) using enzymes from different

99 accumulate TMAO to protect proteins, such as lactate dehydrogenase (LDH), against hydrostatic pressur

100 aluated for prostate-specific antigen (PSA), lactate dehydrogenase (LDH), and CgA at baseline and in

101 B), that is distinct from the flavoprotein L-lactate dehydrogenase (LldD).

102 lternative, iron-sulfur cluster-containing L-lactate dehydrogenase (LutACB), that is distinct from th

103 ary plasma cell leukaemia and elevated serum lactate dehydrogenase (two times the upper limit of norm

104 ssive tumors to enhanced glycolytic flux and lactate dehydrogenase A (LDHA) activity (Warburg effect)

105 monophosphate synthetase (UMPS), as well as lactate dehydrogenase A (LDHA), establishing a mechanism

106 ng of cell metabolism towards glycolysis and lactate dehydrogenase A (LDHA).

107 In contrast to pO(2) and (18)F-FDG uptake, lactate dehydrogenase activity was distributed relativel

108 The results of a lactate dehydrogenase assay indicated that exposure to t

109 ; release of IL-1beta, IL-18, caspase-1, and lactate dehydrogenase from the cell; and real-time analy

110 Ninety minutes lactate dehydrogenase had the strongest correlation with

111 14.4]; P = .035), d-dimer level (P < .001), lactate dehydrogenase level (P < .001), and C-reactive p

112 dgkin's lymphoma (stage III with an elevated lactate dehydrogenase level or stage IV) or acute leukem

113 evel was observed in 139 (88%), and elevated lactate dehydrogenase level was observed in 128 (81%).

114 neutrophil count, C-reactive protein level, lactate dehydrogenase level, distribution of lung diseas

115 cell count, neutrophil/lymphocyte ratio, and lactate dehydrogenase level.

116 nd point, including survival in the elevated lactate dehydrogenase or EGFR and ALK wild-type populati

117 helial cells, pH, D/L-lactate production and lactate dehydrogenase relative abundance were assessed.

118 tobacilli adhesion to epithelial cells and D-lactate dehydrogenase relative abundance.

119 n flux from pyruvate to lactate catalyzed by lactate dehydrogenase using hyperpolarized (13)C magneti

120 ventional fluid biomarkers (pH, glucose, and lactate dehydrogenase) in parapneumonic effusions.Method

121 ion of an NADH-dependent dehydrogenase (i.e. lactate dehydrogenase), via EDC/S-NHS chemistry, for the

122 (14;20), four (4%) of 100 had elevated serum lactate dehydrogenase, and 17 (17%) had two or more feat

123 We identified markers of inflammation, lactate dehydrogenase, and creatinine as the variables m

124 ormalities, such as lymphopenia and elevated lactate dehydrogenase, are common, but nonspecific.

125 , aldolase A and pyruvate kinase, as well as lactate dehydrogenase, are enriched at the C. trachomati

126 aminotransferase, alanine aminotransferase, lactate dehydrogenase, glucose, lactate, and pH) with gr

127 Catfish L-lactate dehydrogenase, glyceraldehyde-3-phosphate dehydr

128 corporating simple clinical parameters (age, lactate dehydrogenase, number/sites of involvement, stag

129 filtration rate levels, and had higher serum lactate dehydrogenase, procalcitonin, and interleukin-6

130 ance of high glycolytic rates depends on the lactate dehydrogenase-catalyzed regeneration of NAD(+) f

131 Lactate dehydrogenases (LDHs) are tetrameric enzymes of

132 uced changes in beta-1,3-glucan exposure are lactate-dependent; and high iron causes beta-1,3-glucan

133 ed, ketone bodies generated in the liver and lactate derived from exercising skeletal muscle can also

134 tion of a Bio-Nano-PEDOT-based biosensor for lactate detection which had a response time of less than

135 lls also reduced the expression of LDHA (and lactate), DHODH, and UMPS but did not affect UMP levels,

136 view, we describe how the bioavailability of lactate differs in the microenvironments of tumours and

137 on of hyperpolarized (13)C-pyruvate to (13)C-lactate during the one-minute measurement increased by a

138 minant negative connexin 43 or by disrupting lactate efflux was sufficient to mimic the effects of st

139 herapy-especially when liver failure reduces lactate elimination.

140 Net cerebral glucose/lactate exchange, and biomarkers of oxidative and inflam

141 dification rate, glycolytic metabolites, and lactate excretion.

142 Lactating female baboons form close ties ("primary assoc

143 Chronic kidney disease, lactate, ferritin, and fibrinogen were associated with m

144 These data highlight the key role of lactate fluxes in finely tuning the metabolic activity o

145 ectional and simultaneous inward and outward lactate fluxes, which were required for efficient utiliz

146 by clinically accurate predictions of pH and lactate from unknown samples in the physiologically rele

147 Vitamin K2-increased glucose consumption and lactate generation, indicating that Vitamin K2 promotes

148 bonate), and significantly lowered levels of lactate, glucose, and apoptosis.

149 ance and diversity of oral bacteria, and pH, lactate, glucose, nitrate and nitrite concentrations.

150 e levels (glucose uptake, and intracellular- lactate, glutamine, and glutamate).

151 severe glucose metabolic disorders in MGs of lactating goats, shifting lactose synthesis to acute fer

152 a qSOFA score greater than or equal to 1 or lactate greater than 2 mmol/L (91.3%; 95% CI, 89.0-93.2)

153 igher body mass index categories observed at lactate greater than 5 mmol/L.

154 eeding seasons we measured resting HRV of 57 lactating grey seals.

155 on, the triage SIRS criteria and the initial lactate > 3 mmol/L had sensitivities of 82% and 65%, res

156 her among individuals with high baseline CSF lactate >5 mmol/L (35%; 38/109) as compared to individua

157 Individuals with high CSF lactate >5 mmol/L at cryptococcal diagnosis more likely

158 After multivariate adjustment, CSF lactate >5mmol/L remained independently associated with

159 Among those with hyperlactataemia (blood lactate >=5.0 mmol/L), transfusion was not significantly

160 Here we asked whether lactate has any paracrine role via activation of GPR81 i

161 nction such as CRP, platelet count and serum lactate have to be taken into account for therapy monito

162 ylethyl alcohol, diethyl succinate and ethyl lactate having the highest flavor dilution factor.

163 hour survival rates, mean arterial pressure, lactate, hemoglobin, and estimated intravascular volume

164 Finally, we demonstrated that significant lactate import through MCT1 occurs even when glucose is

165 tate being a more prominent source of tumour lactate in efficient metastasizers.

166 We measured CSF lactate in individuals with cryptococcal meningitis to d

167 from Meyerhof's experiments on oxidation of lactate in isolated muscles recovering from electrical c

168 mate, glutamine, gamma-aminobutyric acid and lactate in the brains of unaffected and glioma-bearing r

169 (50% control) concentrations of pyruvate and lactate in the first step medium and EAA and Glu in the

170 roscopy, for continuous monitoring of pH and lactate in vivo.

171 effects, cardiac output declined and plasma lactate increased probably due to a predominantly system

172 Treatment of BMDMs with lactate increased the intracellular NADH/NAD(+) ratio an

173 Lactate increases brown adipogenesis in both mouse and h

174 ompared with control subjects, and bacterial lactate increases IL-10 production by human monocyte-der

175 auses beta-1,3-glucan exposure by preventing lactate-induced, Crz1-mediated inhibition of activation

176 co-cultures, we show that bacterial-derived lactate inhibits histone deacetylase 11, causing uncheck

177 Lactate initiates Mg(2+) release from the ER and subsequ

178 L-lactate is an abundant metabolite in a number of niches

179 Lactate is now appreciated as a crucial energy source, m

180 H/(2)H NMR method to measure the kinetics of lactate isotopomer and HDO production using a deuterated

181 Increased T(1) of (2)H-lactate isotopomers indicates inversion/saturation recov

182 Serum lactate (LA) may be elevated in patients with CLD due to

183 intratumoral metabolic heterogeneity, where lactate labeling correlated with MCT1 expression and hyp

184 t use (7 vs 0; p = 0.03), and a higher day 1 lactate level (10.0 vs 5.1; p = 0.02).

185 rtension (8 vs 4; p = 0.047), a higher day 1 lactate level (12.6 vs 5.8; p = 0.02), and a lower pH le

186 A high CO2 gap was associated with higher lactate levels (mean difference 0.44 mmol/L; 95% CI, 0.2

187 eline CSF lactate levels and blood capillary lactate levels (p=.72).

188 atio, 1.05 [95% CI, 1.01-1.08]; P=0.007) and lactate levels after 12 hours of MCS (hazard ratio, 1.28

189 We found no correlation between baseline CSF lactate levels and blood capillary lactate levels (p=.72

190 Blood lactate levels are elevated in both heat-sensitive MHS p

191 Cerebrospinal fluid (CSF) lactate levels can differentiate between bacterial and v

192 /-) mouse, suggesting that the regulation of lactate levels in the RPE and the subretinal space is es

193 dium and magnesium and decreased albumin and lactate levels were detected in animals euthanized with

194 Lactate levels were weakly correlated with CI following

195 ss index was smaller in patients with higher lactate levels with no mortality benefit in higher body

196 T1 inhibitor SR13800 increased intracellular lactate levels, disrupted the nicotinamide adenine dinuc

197 ge (3.1 to 5 mmol/L) or low (<=3 mmol/L) CSF lactate levels.

198 icon sequence analyses revealed that acetate/lactate mainly enriched Geobacter, while in situ OM supp

199 ronutrients to match the requirements of the lactating mammary gland.

200 lert, including number of blood cultures and lactate measurements taken, percentage of patients recei

201 onditions and reinforce the emerging role of lactate metabolism in the control of energy homeostasis.

202 lic trajectories and molecules that regulate lactating MGs with an excessive glucose supply.

203 ed nucleus of the stria terminalis (BNST) of lactating mice during maternal care and analysed locomot

204 Together, these findings reveal that lactate mobilizes (i)Mg(2+) and links the (m)Mg(2+) tran

205 gent from an inexpensive phenol containing a lactate moiety as the chiral auxiliary.

206 n human breast milk, we identified groups of lactating mothers, which mirror the ones found in mice t

207 sotopes, in 6-week postpartum women who were lactating (n = 12) or formula-feeding (n = 6) their infa

208 both 24 h and 48 h measurements, the rise in Lactate/N-acetyl aspartate was reduced in white (p = 0.0

209 ability to detect HB along with glucose and lactate on a single microneedle array has been demonstra

210 cally important whether quantified as higher lactate or by Acute Physiology and Chronic Health Evalua

211 of 3.0-3.3 angstrom, of human MCT1 bound to lactate or inhibitors in the presence of Basigin-2, a si

212 tward-open conformations when complexed with lactate or the inhibitors BAY-8002 and AZD3965.

213 who received fluid bolus (10mL/kg of Ringers-Lactate over 30 min) for management of shock and/or hypo

214 We engineered LOXCAT, a fusion of bacterial lactate oxidase (LOX) and catalase (CAT), which irrevers

215 The l-lactate oxidase (LOx) based lactate sensors are widely u

216 The device comprises a lactate oxidase and osmium-polymer -based anode connecte

217 s significantly associated with baseline CSF lactate (p=.03).

218 ither the nonlactating "dry" period (EDP) or lactating period (EL).

219 o by simultaneous measurement of glucose and lactate, pH, and skin temperature.

220 nsing of sweat biomarkers including glucose, lactate, pH, chloride, and volume.

221 Addition of pyruvate and L-lactate (+PL) to RN at 50% of standard concentrations re

222 The lactate platform demonstrates the benefits of mixed cult

223 uction, while pO(2) was inversely related to lactate production and (18)F-2-fluoro-2-deoxy-D-glucose

224 dhesion to vaginal epithelial cells, pH, D/L-lactate production and lactate dehydrogenase relative ab

225 metabolism from oxidative phosphorylation to lactate production for energy generation, malignant tumo

226 Meanwhile, increased lactate production from glucose, known as aerobic glycol

227 city, evidenced by increased glucose-derived lactate production upon ROS inhibition.

228 sitive correlation between (18)F-FDG-PET and lactate production, while pO(2) was inversely related to

229 of glycolysis, leading to an augmentation in lactate production.

230 l cells and microbiome, leading to increased lactate production.

231 in defective aerobic glycolysis and reduced lactate production.

232 ase activity, together with increased muscle lactate production.

233 95% of glucose consumed was accounted for by lactate production; however, high concurrent oxygen cons

234 reveal that microbial-derived D-lactate promotes Kupffer-cell-mediated killing of circul

235 range of metabolites relating to glycolysis (lactate, pyruvate, succinate).

236 ability over time and was found suitable for lactate/pyruvate ratio detection in biological samples.

237 ble for use as a binding moiety to develop a lactate/pyruvate ratio FRET-based genetically encoded in

238 ent approaches do not allow detection of the lactate/pyruvate ratio in a single readout with high spa

239 licheniformis is an endogenous sensor of the lactate/pyruvate ratio, suitable for use as a binding mo

240 o, blunted a metformin-induced rise in blood lactate:pyruvate ratio and improved NADH:NAD(+) balance

241 vein-injected LOXCAT lowered the circulating lactate:pyruvate ratio, blunted a metformin-induced rise

242 transport chain decreased the extracellular lactate:pyruvate ratio, normalized the intracellular NAD

243 be in near equilibrium with the circulating lactate:pyruvate ratio, we hypothesized that reductive s

244 aminotransferase (R = 0.420, P = 0.029), and lactate (R = 0.574, P = 0.002).

245 with the previously described structures of lactate racemase holoprotein and D-gluconate epimerase a

246 s of PTR and G6PD deficiency (e.g., pyruvate/lactate ratios), along with potential compensatory pathw

247 tomy followed by controlled hemorrhage until lactate reached 7.5-8.5 mmol/L.

248 ly, the gold standard for the measurement of lactate requires blood sampling.

249 However, lactate's ability to stimulate neurogenesis is reversed

250 Not only do we expect lactating seals to display energy compensation because o

251 hese results indicated that a quasi-DET type lactate sensor was developed that did not suffer from th

252 si-direct electron transfer (quasi-DET) type lactate sensor was developed using rationally engineered

253 The l-lactate oxidase (LOx) based lactate sensors are widely used for clinical diagnostics

254 erent effects are inherent issues of current lactate sensors.

255 ore dissolved As was detected in the acetate/lactate setups, after 100 days, higher concentrations of

256 l basis should now be understood in light of lactate shuttle biology.

257 ]-labeled glucose experiments did not reveal lactate shuttling into LECs from breast cancer cells, ye

258 btypes (mean +/- SD: 0.145 +/- 0.164), and a lactate signal was observed in all of the grade 3 tumors

259 rogeneity of the hyperpolarized pyruvate and lactate signals were observed.

260 Induction of cathodic electron uptake by lactate-starved D. ferrophilus IS5 cells resulted in the

261 cant metabolic differences in perfusate (eg, lactate, succinate, flavin mononucleotide) and tissues (

262 hermore, direct restoration of the astrocyte lactate supply alone rescued stress-impaired synaptic pl

263 rgeted resuscitation strategy is superior to lactate-targeted resuscitation at 28 days was above 90%

264 on of organ dysfunction when compared with a lactate-targeted resuscitation strategy.

265 g; leading to a reduction in accumulation of lactate that signals through the transcription factor Cr

266 La(-) accumulates in the arterial blood (the lactate threshold; LT).

267 ress constrains the shuttling of glucose and lactate through astrocyte networks, creating a barrier f

268 GFP-DDDHA, which was induced by trimethoprim-lactate (TMP-lactate), which results in the death of int

269 of labeled carbon transfer from pyruvate to lactate to detect early response and FOXM1-mediated resi

270 uld be alleviated by oxidizing extracellular lactate to pyruvate.

271 10 to 0.089 +/- 0.039 (P = .005), and in the lactate-to-glucose ratio, from 0.27 +/- 0.12 to 0.12 +/-

272 The (13)C-labeled lactate-to-pyruvate ratio derived from hyperpolarized (1

273 herapy, a 34% reduction in the (13)C-labeled lactate-to-pyruvate ratio resulted in correct identifica

274 The lactate-to-pyruvate signal ratio (LAC/PYR) ranged from 0

275 nts on five animals showed a decrease in the lactate-to-water signal ratio, from 0.33 +/- 0.10 to 0.0

276 tabolon disruption" results in a decrease in lactate transport, reduced glycolysis, and ultimately re

277 CAIX-mediated facilitation of proton-coupled lactate transport.

278 we discovered and validated the plasmodial l-lactate transporter, PfFNT, as a novel antimalarial drug

279 The loss of lactate transporters from the RPE most closely resembled

280 To explore the function of the lactate-transporting monocarboxylate transporters (MCTs)

281 city, which was blocked by inhibiting neural lactate uptake.

282 vels of MCT1, and inhibition of MCT1 reduced lactate uptake.

283 les (n = 16 cycling, n = 36 pregnant, n = 39 lactating) using 16S rRNA gene amplicon sequencing and a

284 outcome have been observed: age, female sex, lactate value, Model of End-Stage Liver Disease XI score

285 the areas of diffusion-weighted abnormality, lactate was lower where recovery was observed compared w

286 formation of the corresponding product when lactate was the electron donor, and the fluorinated comp

287 ed that glutamine, alanine, glutathione, and lactate were positively associated with the first inflam

288 establishes a novel function for lactate whereby it is utilized in a new histone modifica

289 ich was induced by trimethoprim-lactate (TMP-lactate), which results in the death of intracellular pa

290 GPR81 is a G-protein-coupled receptor for lactate, which is upregulated in breast cancer and plays

291 We evaluated the association of CSF lactate with clinical characteristics and survival.

292 LDH) catalyzes the conversion of pyruvate to lactate, with concomitant oxidation of reduced nicotinam

293 w insulin concentrations of both groups, the lactating women exhibited a fasting rate of endogenous g

294 In the lactating women only, higher prolactin concentrations we

295 e randomized controlled trials including 567 lactating women were included.

296 Materials and Methods Lactating women with palpable breast masses evaluated at

297 ion Targeted US depicted all malignancies in lactating women with palpable masses.

298 mastitis (SAM) is a prevalent disease among lactating women, being one of the main reasons for early

299 modality for palpable masses in pregnant and lactating women, but data regarding breastfeeding women

300 ide clinically important benefits for BMD in lactating women.