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1 triblock polymers, where PLA stands for poly(lactide).
2 comprising poly(dodecyl acrylate)-block-poly(lactide).
3 and utilized in the polymerization of (rac)-lactide.
4 a change in the rate of polymerization of L-lactide.
5 during the ring-opening polymerization of L-lactide.
6 enyl isocyanate and the polymerization of DL-lactide.
7 as initiators for the polymerization of rac-lactide.
8 a cis-rich telechelic polyoctenamer with d,l-lactide.
9 tal-catalyzed ring-opening polymerization of lactide.
10 the catalyzed ring opening polymerization of lactide.
11 cles composed of l-lactide homopolymer and l-lactide/1,3-dioxolane (co)polymers loaded with quercetin
16 led anionic ring-opening copolymerization of lactide and a cyclic phosphate allowed PLA to be prepare
17 ted with a 10% copolymer solution of 50:50 L-lactide and epsilon-caprolactone were statically seeded
20 ymer scaffolds fabricated from copolymers of lactide and glycolide were adsorbed with collagen IV, fi
21 nd biodegradable PLGA (a random copolymer of lactide and glycolide) to form a nanofibrous non-woven s
23 ormation pertaining to the polymerization of lactide and other cyclic esters by discrete metal alkoxi
25 omonomers including commercially available l-lactide and trimethylene carbonate produced novel copoly
26 1,4-dioxane-2,5-dione was synthesized from L-lactide and used as the dienophile to prepare spiro[6-me
29 ac-LA is kinetically polymerized into poly(L-lactide) and optically resolved D-LA, with a high stereo
30 ic multi-block copolymers composed of poly(l-lactide) and poly ethylene glycol/poly(-caprolactone), a
31 The stereocomplexation of isotactic poly(L-lactide) and poly(D-lactide) has led to improved propert
32 copolymers of clinically validated poly(D,L-lactide) and poly(ethylene glycol) (PEG-Dlink(m)-PDLLA)
33 ing around Ti-6Al-4V, poly(L-lactide-co-D,L,-lactide), and 303 stainless steel implants with surface
35 polymerization of rac-lactide, L-lactide, DL-lactide, and caprolactone, followed by their photophysic
36 generally applicable to many other lactones, lactides, anhydrides, epoxides, and heterocumulenes and
41 udies also showed that L(1)ZnOEt polymerizes lactide at a rate faster than any other Zn-containing sy
42 catalyze the ring-opening polymerization of lactide at elevated temperatures to give narrowly disper
45 reocomplex micelles from a mixture of poly(L-lactide)-b-poly(acrylic acid) and poly(D-lactide)-b-poly
46 y(L-lactide)-b-poly(acrylic acid) and poly(D-lactide)-b-poly(acrylic acid) diblock copolymers in wate
47 trated by their use in the synthesis of poly(lactide)-b-poly(butenediol)-b-poly(lactide) triblock cop
49 xidation state and its subsequent monomer (l-lactide, B-butyrolactone, or cyclohexene oxide) selectiv
50 te hydrogels, we show that the use of poly(L-lactide)-based nanoparticles with platelet morphology as
51 lyl/benzyl)oxy-6-(H/alkyl)-2-oxy-benzoate-co-lactide-based polymer library was designed and studied f
52 forms across a substantial range of minority lactide block volume fractions (f (L) = 0.25 - 0.33) sit
53 n-driven self-assembly (ROPI-CDSA) of poly-L-lactide-block-polyethylene glycol block copolymers into
56 ion from a dynamic combinatorial library and lactide can be converted to (MeCHC(O)O)6 in >80% yield.
57 rned matrix based on acrylate-functionalized lactide-chain-extended star polyethylene glycol (SPELA)
58 e encapsulated SOD in biodegradable poly(D,L-lactide co-glycolide) nanoparticles (SOD-NPs) and tested
60 ere derived from poly(ethyleneglycol)-b-poly(lactide)-co-poly(N(3)-alpha-epsilon-caprolactone) with a
61 ne serum albumin (BSA) in injectable poly(DL-lactide- co-glycolide) (PLGA) 50/50 cylindrical implants
62 We assessed healing around Ti-6Al-4V, poly(L-lactide-co-D,L,-lactide), and 303 stainless steel implan
63 fabricated with thiolated chitosan and poly(lactide-co-E-caprolactone) (PLACL) was designed to achie
64 , self-adhesive, shape-transformable poly (L-lactide-co-epsilon-caprolactone) (BSS-PLCL) that can be
65 days of culture in the presence of poly(D,L-lactide-co-epsilon-caprolactone) (PDLLCL), poly(ethylene
66 monstrate that the prevascularized poly (D,L-lactide-co-epsilon-caprolactone) scaffold maintains viab
68 ctive MgSO(4) particles into a PLCL (poly (l-lactide-co-epsilon-caprolactone)) substrate using 3D pri
69 The coating consisted of absorbable poly-lactide-co-glycolic acid (PLGA) and crystalline sirolimu
70 tion of a US contrast agent composed of poly-lactide-co-glycolic acid polymeric (PLGA) microspheres (
71 rowth factor 7-loaded galactosylated poly(DL-lactide-co-glycolic acid) (FGF7-GAL-PLGA) particles; 26-
72 ) encapsulated in negatively charged poly(dl-lactide-co-glycolic acid) nanoparticles, is designed to
73 0 nm) and for NPs made of PEGylated poly-d,l-lactide-co-glycolide (PEG-PLGA, a biocompatible FDA-appr
75 ctone (PCL), poly-D,L-lactide (PLA), or poly-lactide-co-glycolide (PLGA), and hydrophilic blocks of p
76 matory mediators, encapsulated into poly(d,l-lactide-co-glycolide acid) (PLGA), and coated with a fin
78 deslorelin or transferrin-conjugated poly-l-lactide-co-glycolide nanoparticles (PLGA-NPs) encapsulat
80 en-conjugated NPs made of biodegradable poly(lactide-co-glycolide) (Ag-PLG) are similarly effective p
82 this approach was evaluated by using 3D poly(lactide-co-glycolide) (PLAGA) sintered microsphere scaff
83 otein bovine serum albumin (BSA)-loaded poly(lactide-co-glycolide) (PLG) core and drug-free poly(d,l-
85 virus RNA replicons (pSINCP), cationic poly(lactide-co-glycolide) (PLG) microparticles for DNA deliv
86 ctive of this study was to determine if poly(lactide-co-glycolide) (PLG) nanoparticles (NPs) loaded w
87 Os required a bioartificial microporous poly(lactide-co-glycolide) (PLG) scaffold niche for successfu
88 nvestigated the surface modification of poly(lactide-co-glycolide) (PLG) scaffolds with polysaccharid
90 ition 50:50 poly (DL-lactide) (PLA)/poly (DL-lactide-co-glycolide) (PLG) with an inherent viscosity o
91 Nanoparticles were formed from 50:50 poly(DL-lactide-co-glycolide) (PLG) with two molecular weights (
92 ng solvent-extrusion, we formulated poly(D,l-lactide-co-glycolide) (PLGA) 50/50 milli-cylinder implan
93 pH-responsive nanoparticle based on poly(D,L-lactide-co-glycolide) (PLGA) and chitosan (CHIT) for del
94 u forming implant formulations based on poly(lactide-co-glycolide) (PLGA) and N-Methyl-2-Pyrrolidone
96 long-acting formulations, specifically poly(lactide-co-glycolide) (PLGA) based systems, have been us
97 his approach, LNG was encapsulated in a poly(lactide-co-glycolide) (PLGA) core surrounded by a poly(l
101 ticles, microparticles, implants of poly(D,l-lactide-co-glycolide) (PLGA) have been demonstrated for
102 injectable (LAI) formulations based on poly(lactide-co-glycolide) (PLGA) have been developed to deli
103 long-acting depot formulations based on poly(lactide-co-glycolide) (PLGA) have been used clinically s
105 duced to change the properties of a poly(d,l-lactide-co-glycolide) (PLGA) matrix, thereby altering th
107 In this study we prepared large porous poly(lactide-co-glycolide) (PLGA) microparticles of celecoxib
108 ology for prediction of the size of poly(D,L-lactide-co-glycolide) (PLGA) microparticles produced by
111 t a subcutaneous injection of PEGylated poly(lactide-co-glycolide) (PLGA) nanoparticles containing au
114 to 50% in the group using biodegradable poly(lactide-co-glycolide) (PLGA) nonwoven nanofibrous membra
115 ophosphoryl Lipid A encapsulated in poly(d,l-lactide-co-glycolide) (PLGA) NPs were used as the vaccin
117 14 and different carbohydrates-modified poly(lactide-co-glycolide) (PLGA) or poly(lactide-coglycolide
118 used to encapsulate the MRI agent in a poly(lactide-co-glycolide) (PLGA) or polylactide-poly(ethylen
121 of parenteral formulations comprised of poly(lactide-co-glycolide) (PLGA) requires assays of the rele
123 mers, poly(epsilon-caprolactone) (PCL), poly(lactide-co-glycolide) (PLGA), and poly(ethylene vinyl ac
124 series of bioresorbable polymers, i.e., poly(lactide-co-glycolide) (PLGA), poly(lactic acid) (PLLA),
126 In this study, we used cationic lipid-poly(lactide-co-glycolide) acid (PLGA) hybrid nanoparticles a
127 (chitosan and lecithin) and synthetic (poly(lactide-co-glycolide) and Eudragit S100(R) (ES100)) poly
129 s elicited by a vaccine system based on poly(lactide-co-glycolide) micro- or nano-particles enveloped
130 tidylic acid) (polyIC) in biodegradable poly(lactide-co-glycolide) microparticles (MPs) designed to r
132 ovine serum albumin was encapsulated in poly(lactide-co-glycolide) microparticles and was administere
134 of either polystyrene or biodegradable poly(lactide-co-glycolide) microparticles bearing encephalito
137 0 to 500 microns ganciclovir-loaded poly(D,L-lactide-co-glycolide) microspheres control the progressi
138 d efficacy of negatively charged 500-nm poly(lactide-co-glycolide) nanoparticles encapsulating gliadi
139 h a collagen matrix, was added to a poly (DL-lactide-co-glycolide) polymer (PLG) and placed at orthot
141 , PTX was covalently conjugated to poly (D,L-lactide-co-glycolide) polymeric core by redox-sensitive
142 bioabsorbable nanofibrous membranes of poly(lactide-co-glycolide) were effective to reduce adhesions
145 -printed patches composed of a blend of poly(lactide-co-glycolide), polycaprolactone, and 5-fluoroura
146 gradable and biocompatible polymer, poly(d,l-lactide-co-glycolide), was used to fabricate curcumin mi
147 orous scaffolds of biomineralized 85:15 poly(lactide-co-glycolide), which locally release vascular en
148 n of a cationic amphiphilic copolymer, poly (lactide-co-glycolide)-graft-polyethylenimine (PgP) and i
150 we engineered a composite fibrin-PLGA [poly(lactide-co-glycolide)]-sintered microsphere scaffold for
152 thetic controlled-release biomaterials, poly(lactide-co-glycolide; PLGA) microparticles (MPs) encapsu
153 affords the synthesis of lactone rich poly(l-lactide-co-lactone) statistical copolymeric blocks, whil
154 uncoated or coated with a thin layer of poly(lactide-co-sigma-caprolactone) copolymer alone or contai
156 v adsorbed onto the surface of cationic poly(lactide-coglycolide) (PLG) microparticles were shown to
158 poration of peptides in bioadhesive poly(D,L-lactide-coglycolide) (PLGA) microparticles, the use of m
159 ound I nanoparticle (compound I-NP)] in poly(lactide-coglycolide) (PLGA) was developed that shows sus
162 ogenic inhibitor, was encapsulated with poly(lactide-coglycolide) to form K5 nanoparticles (K5-NP).
163 ed poly(lactide-co-glycolide) (PLGA) or poly(lactide-coglycolide)-b-poly(ethylene glycol) (PLGA-PEG)
164 hrough self-assembly of a biodegradable poly(lactide-coglycolide)-b-poly(ethylene glycol) diblock cop
166 A bioabsorbable membrane of glycolide and lactide copolymer was sutured over the defect to maximiz
168 ive and controlled polymerization of racemic lactide (D,L-LA) using an initiator prepared in situ fro
169 zation of several common monomers, including lactide, delta-valerolactone, epsilon-caprolactone, a cy
172 mmetric low molar mass poly(isoprene)-b-poly(lactide) diblock copolymers reveal an extraordinary ther
173 , including polymerization of rac-lactide, L-lactide, DL-lactide, and caprolactone, followed by their
175 ot the case as a fraction incorporating meso-lactide due to racemization occurring during the synthes
176 ld enable a sequential polymerization of the lactide enantiomers to afford stereoblock copolymers wit
177 bles controlled copolymerization of OCAs and lactide, facilitating the synthesis of block copolymers
178 mately 10 to approximately 110 mug/min), and lactide from polylactic acid (PLA) filaments (ranging fr
180 LGA attributes, i.e., molecular weight (MW), lactide:glycolide (L/G) ratio, blockiness, and end group
181 LGA attributes (i.e., molecular weight (MW), lactide:glycolide (L/G) ratio, blockiness, and end group
182 ecular weight standards, and determining the lactide:glycolide (L: G) ratio by (1)H NMR and the end-g
183 ed for characterization of Glu-PLGA with the lactide:glycolide (L:G) ratio of 55:45 used in Sandostat
187 a-butyrolactone, and D, L, meso, and racemic lactides has been studied with the PHB-depolymerase (P.
188 tion of isotactic poly(L-lactide) and poly(D-lactide) has led to improved properties compared with ea
189 in the polymerization of either meso- or rac-lactide, homochiral 4 was found to exhibit excellent ste
190 this challenge, microparticles composed of l-lactide homopolymer and l-lactide/1,3-dioxolane (co)poly
191 n a sphere (micelle) forming poly(isoprene-b-lactide) (IL) diblock copolymer melt, investigated as a
192 cticity to produce stereoblock PLA, from rac-lactide improves thermal properties but is an outstandin
193 zwitterionic ring-opening polymerization of lactide initiated by N-heterocyclic carbenes generates c
195 strially relevant bulk polymerization of rac-lactide is also demonstrated and provides key insights f
196 )Cl(-) (PPN(+)Cl(-)) selectively polymerizes lactide (L and rac) dissolved in neat propylene oxide (P
197 ol (PEG) macromers chain-extended with short lactide (L) and glycolide (G) segments were used for gra
199 d reactions, including polymerization of rac-lactide, L-lactide, DL-lactide, and caprolactone, follow
202 ered to catalyze rapid epimerization of meso-lactide (LA) or LA diastereomers quantitatively into rac
203 for the ring-opening polymerization (ROP) of lactide (LA) to form poly(lactic acid) (PLA) at room tem
204 rol for the stereospecific polymerization of lactide (LA) were investigated through studies of alumin
206 yclic lactone, and show that copolymers of l-lactide (LA) with small amounts of ODO have improved mec
207 of isocyanate, polymerization process for L-lactide (LA), methyl methacrylate (MMA) and dehydrosilyl
208 t block copolymerization of betaMdeltaVL and lactide leads to a new class of high-performance polyest
209 on of styrene and divinylbenzene from a poly(lactide) macro-chain transfer agent in the presence of n
213 e form or orally after encapsulation in poly(lactide) microspheres, induced significant protective im
214 study indicates that insertion of the first lactide monomer into the tin(II) alkoxide bond is facile
216 ree iodinated monomeric moieties (a modified lactide, morpholine-2,5-dione, and caprolactone), which
217 ne) (mPEG-CL) and poly(ethylene glycol-block-lactide) (mPEG-LA) were unstable in fetal bovine serum,
218 oxy poly(ethyleneglycol)-b-poly(carbonate-co-lactide) [mPEG-b-P(CB-co-LA)] polymeric nanoparticles by
219 VEGF detection, and incorporated with poly-L-lactide nanoparticles (PLLA NPs) for signal amplificatio
220 yclooctadiene) and copolymerizing it with DL-lactide, novel polymeric alloys of PLA can be created th
221 Our previous study showed that poly(d,l-lactide) NPs conjugated with an antielastin antibody cou
224 ies on self-assembly of poly(butadiene)-poly(lactide) (PB-PLA) diblock copolymers followed by selecti
226 odegradable poly(ethylene glycol)-b-poly(d,l-lactide) (PEG-PDLLA) block copolymers, with the two bloc
229 s cores while poly(ethylene oxide)-co-poly(l-lactide) (PEG-PLLA) formed micelles with solid crystalli
230 seed and skin were stabilized with poly-d,l-lactide (PLA) polymer by the emulsion-evaporation method
232 ), poly-epsilon-caprolactone (PCL), poly-D,L-lactide (PLA), or poly-lactide-co-glycolide (PLGA), and
233 ed bone allograft (DFDBA) (BG+PDox); poly(DL-lactide) PLA barrier without doxycycline + DFDBA (BG+P);
234 wo molecular weights (Low, High) and poly(DL-lactide) (PLA) (termed PLG-L, PLG-H, and PDLA, respectiv
235 sembled from a block copolymer of poly (D, L-lactide) (PLA) and monomethoxy polyethylene glycol (mPEG
236 as an initiator to form copolymers with poly(lactide) (PLA) and poly(epsilon-caprolactone) (PCL).
237 poly(l-lactide) (PLLA) shell and a poly(D,L-lactide) (PLA) cap that were fabricated by sequential ca
238 we sought to develop an injectable poly(D,l-lactide) (PLA) microparticle for sustained release of co
239 cells were cultured within either poly (D,L-lactide) (PLA) or a fused fiber ceramic and evaluated fo
240 ssfully applied to mixtures of cyclic poly(L-lactide) (PLA) with increasing amounts of its linear top
241 zations of selected diluents with a poly(d,l-lactide) (PLA), polydimethylsiloxane (PDMS), or polystyr
242 polymer film with composition 50:50 poly (DL-lactide) (PLA)/poly (DL-lactide-co-glycolide) (PLG) with
244 e sequence PISA protocol that employs poly(l-lactide) (PLLA) as the crystallizable core-forming block
246 lycolide) (PLGA) core surrounded by a poly(l-lactide) (PLLA) shell and a poly(D,L-lactide) (PLA) cap
247 O), poly(epsilon-caprolactone) (PCL), poly(L-lactide) (PLLA), and polyglycolide (PGA), with a composi
251 ly to one of three treatment groups: poly(DL-lactide) polylactic acid (PLA) barrier containing 4% dox
252 These case reports suggest that a poly(DL-lactide) polymer can be used as a physical barrier with
254 n, structural characterization, and detailed lactide polymerization behavior of a new Zn(II) alkoxide
255 PLA chain length in controlled solvent-free lactide polymerization combined with heavy-atom substitu
256 e oxidation state of the catalyst: selective lactide polymerization was observed in the iron(II) oxid
257 When redox reactions were carried out during lactide polymerization, catalysis could be switched off
262 extremely fast for the polymerization of rac-lactide, polymerizing 500 equiv in 96% yield in less tha
264 catalyst to these polyols in the presence of lactides produces well-defined triblock copolymers (PLA-
271 et of literature results for stereoselective lactide ring-opening polymerization, and using the algor
272 the pK(a) of [M(OH(2))(m)](n+)), whilst the lactide ROP activity and CO(2)/epoxide selectivity show
274 effect the stereoselective polymerization of lactides starting from a single achiral precursor and th
275 (0) = 0.84 M, [InX(3)](0)/[BnOH](0) = 1) and lactide stereoisomer (i.e., k(obs)(D,L-LA) approximately
276 cribe an approach to ordered nanoporous poly(lactide) that relies on self-assembly of poly(butadiene)
280 (PLA), while rac-4 polymerizes meso- and rac-lactide to heterotactic and isotactic stereoblock PLA, r
281 LA without epimerization of the monomer, rac-lactide to heterotactic PLA (P(r) = 0.94 at 0 degrees C)
282 [(BDI-1)ZnO(i)()Pr](2) polymerized (S,S)-lactide to isotactic PLA without epimerization of the mo
284 c PLA (P(r) = 0.94 at 0 degrees C), and meso-lactide to syndiotactic PLA (P(r) = 0.76 at 0 degrees C)
285 Enantiomerically pure 4 polymerizes meso-lactide to syndiotactic poly(lactic acid) (PLA), while r
289 ators for the ring-opening polymerization of lactide under mild conditions, providing polymers with c
290 tion of an in situ formed barrier of poly(DL-lactide) used in combination with a composite graft of d
291 lute stereochemistry of ring-opening of meso-lactide using (R)-4, a polymer exchange mechanism is pro
292 sms for the ring-opening polymerization of l-lactide using a guanidine-based catalyst, the first invo
294 ocess enhances the overall sustainability of lactide/vinyl-based copolymers and demonstrates the syne
296 A bioabsorbable polymer barrier of poly(DL-lactide) was used in conjunction with a composite graft
297 Thus, exo-6 preferentially polymerized l-lactide, whereas endo-6 preferred d-lactide as the subst
298 tyrene) and poly(trimethylsilylstyrene-block-lactide), which were thermally annealed to produce perpe
299 erization and ring-opening polymerization of lactide with DBU (1,8-diazabicyclo[5.4.0]undec-7-ene), f
300 shuttling ring-opening copolymerization of l-lactide with e-caprolactone has been achieved using two