ライフサイエンスコーパス: lactogen

1 rone, placental growth factor, and placental lactogen.

2 es: prolactin, growth hormone, and placental lactogen.

3 genic hormones prolactin (PRL) and placental lactogens.

4 GH genes include placental GHs and placental lactogens.

5 Placental lactogen 1 is an attractive target for future therapeuti

6 t transgenic mice expressing mouse placental lactogen-1 (mPL1) in beta cells under the rat insulin II

7 pment with decreased expression of Placental lactogen-1 and -2 (Pl1 and Pl2) and increased expression

8 in, estradiol, progesterone, human placental lactogen, and prolactin) were measured in conjunction wi

9 in (PRL), growth hormone (GH), and placental lactogen are expressed by endothelia and have angiogenic

10 This study examines whether lactogens can protect beta-cells against ER stress and m

11 owing fetus, whereas prolactin and placental lactogen counterbalance this resistance and prevent mate

12 s of total RNA obtained from PRL-stimulated, lactogen-dependent Nb2-11 cells.

13 imulation and inhibited apoptosis induced by lactogen deprivation (P < 0.001).

14 Human placental lactogen (hPL) is highly conserved with human growth hor

15 We fused human placental lactogen (hPL), a specific and tight binding PRLR ligand

16 ion of the placental hormone human placental lactogen (hPL), experiments were performed to determine

17 lacentas lacking GATA-3 accumulate placental lactogen I and proliferin mRNAs to a level 50% below tha

18 ATA-2 gene had a similar effect on placental lactogen I expression, but led to a markedly greater red

19 ulate transcription from the mouse placental lactogen I gene promoter in a transfected trophoblast ce

20 tors regulate transcription of the placental lactogen I gene, as well as the related proliferin gene,

21 P-C, decidual/trophoblast PRP, and placental lactogen I variant, only which are expressed in the spon

22 Transgenic expression of placental lactogen in beta-cells of Ak mice drastically reduces th

23 lls during pregnancy or after treatment with lactogens in vitro.

24 ot directly involved in cAMP metabolism, the lactogen-induced increase in cAMP was most likely due to

25 t changes in cAMP metabolism are involved in lactogen-induced upregulation of insulin secretion.

26 Bcl-XL-specific siRNA significantly inhibits lactogen-mediated protection against DEX-induced beta ce

27 ve this is the first direct demonstration of lactogens mediating their protective effect through the

28 Lactogens mitigate expression of proapoptotic molecules

29 However, whether lactogens modulate the ER stress pathway is unknown.

30 studies in any cell type demonstrating that lactogens modulate the ER stress pathway, causing enhanc

31 nsactivator of the human and ovine placental lactogen (oPL) genes.

32 Ovine placental lactogen (oPL), a member of the growth hormone/prolactin

33 s (hepatocyte growth factor [HGF], placental lactogen, or parathyroid hormone-related protein) have b

34 In primates, placental lactogen (PL) is a pituitary hormone with fundamental ro

35 It was reported that placental lactogen (PL) plays a crucial role in pregnancy-induced

36 It was reported that placental lactogen (PL) plays a crucial role in pregnancy-induced

37 In this study, we identified placental lactogen (PL), a member of the growth hormone/prolactin

38 enic hormones, prolactin (PRL) and placental lactogen (PL), in beta cell survival.

39 rder to explore the role of murine placental lactogen (PL)-I (mPL-I) in islet mass regulation in vivo

40 and whether FoxM1 is essential for placental lactogen (PL)-induced beta-cell proliferation.

41 During the second half, placental lactogens (PLs) take the place of PRL in maintenance of

42 and expression of Igf2 (+41%) and placental lactogen (Prl3b1: +59%) genes were upregulated in female

43 her, we identify the mechanism through which lactogens protect beta cells against DEX-induced death.

44 We show that lactogens protect INS-1 cells, primary rodent and human

45 The current study demonstrates that lactogens protect rat insulinoma (INS-1) cells and prima

46 Lactogens protect rodent and human beta-cells in vitro a

47 At a time when rat placental lactogens (rPLs) are required to support progesterone pr

48 Prolactin and placental lactogen signal through the prolactin receptor (PRLR) an

49 re we show that serotonin acts downstream of lactogen signaling to stimulate beta cell proliferation.

50 Furthermore, lactogens specifically and significantly increase the an

51 omoter-murine PL-1 (islet-targeted placental lactogen transgenic) mice.

52 ed glucose-stimulated insulin secretion from lactogen-treated islets could be accounted for by increa

53 in the upregulation of islet function after lactogen treatment, we examined the relationship between

54 e-related peptide (PTHrP) or mouse placental lactogen type 1 (mPL1) in pancreatic beta-cells, using t

55 sely related to growth hormone and placental lactogen with properties and functions resembling both a