ライフサイエンスコーパス: lactose

1 ON; containing A1 and A2 beta-casein without lactose).

2 t % fentanyl, 2.6 wt % heroin, and 96.1 wt % lactose).

3 holding 7-fold tighter than the disaccharide lactose.

4 pause for >11 h before initiating growth on lactose.

5 methyllysine (CML) formed between lysine and lactose.

6 more diverse metabolite profile compared to lactose.

7 with a derivative of the pan-galectin ligand lactose.

8 e, which is dependent on the content of beta-lactose.

9 een ones generated by the control and GOS or lactose.

10 cidified milk (800 g) which contained 38.8 g lactose.

11 se, the enzyme required for the digestion of lactose.

12 milk caused by the decreased biosynthesis of lactose.

13 ity upon induction with different amounts of lactose.

14 of bacterial cells to uptake and metabolize lactose.

15 on or removal of a single component, such as lactose.

16 ned by IGC, suggested a surface dominated by lactose.

17 hile LI is caused by the inability to digest lactose.

18 S in sucrose medium than that in glucose and lactose.

19 s along with either amorphous or crystalline lactose.

20 opportunity for expanding the utilization of lactose.

21 the samples (1.36+/-0.89), compared to both lactose (0.45+/-0.12) and glucose (0.46+/-0.13).

22 were, respectively, 0.25 and 0.41mg/100g for lactose, 0.14 and 0.27mg/100g for galactose, and 0.16 an

23 M. pneumoniae also bound lactose 3'-sulfate ligated to an inert polymer scaffold,

24 protein (+8.2 & +13.4%), fat (-9.3 & +0.9%), lactose (-5.4 &-0.7%) and total solids (-2.2 &-3.4%), re

25 e NGLs, as well as the corresponding NGLs of lactose, A type 2 tetrasaccharide, and the GM1 and GD2 p

26 k (CON; containing A1 and A2 beta-casein and lactose), a2 Milk (A2M; exclusively containing A2 beta-c

27 l's ability to absorb dietary lactose and if lactose-absorbers should thus avoid these products.

28 The hydrolysis of lactose affects osmolality, which is an important proper

29 ded beyond the lactose substitution of HepI (lactose alone, Gal-lactose, LNnT, or GalNAc-LNnT), were

30 extensions beyond lactose-substituted HepI (lactose alone, LNnT, or GalNAc-LNnT) as 2C7-Ximab (unmod

31 The location of the drugs and lactose among the particles varied significantly, depend

32 ed of two-steps: (1) enzymatic hydrolysis of lactose and (2) catalytic isomerization over MgO/SiO(2).

33 versions of up to 92% were obtained for pure lactose and 38% for raw lactose from whey.

34 parison to galacto-oligosaccharide (GOS) and lactose and control without additional carbon source.

35 third most abundant component in milk after lactose and fat.

36 ing mammary gland for normal biosynthesis of lactose and for normal growth rates of nursing pups.

37 The influence of lactose and fructose concentration as well as enzymatic

38 t G. stearothermophilus T-1 can also utilize lactose and galactosyl-glycerol via the cellobiose-PTS s

39 d specifically increased with 2'-FL, whereas lactose and GOS also increased lactic acid.

40 es an individual's ability to absorb dietary lactose and if lactose-absorbers should thus avoid these

41 hese commonly measured LM markers after both lactose and milk challenges.

42 ligands of different affinities: galactose, lactose and N-acetyl-lactosamine using tryptophan fluore

43 ins to fucose alleviated growth hindrance by lactose and partially recovered the fluorescence intensi

44 taphylococcal phage S83 was spray-dried with lactose and sodium stearate using spray-drying.

45 Disaccharides such as lactose and sucrose are sugars commonly found in human d

46 s erroneously attribute their GI symptoms to lactose and thus prefer to consume lactose-free products

47 ilks prior to feeding to reduce the level of lactose and to avoid symptoms of lactose intolerance.

48 ilk samples) were analyzed for protein, fat, lactose and total solids by near and mid-infrared transm

49 Properties of both lactose and water were affected by all acids studied.

50 5) or isocaloric modified F75 (mF75) without lactose and with reduced carbohydrate.

51 Lactose and/or pyridoxamine did not induce significant a

52 Lactose and/or pyridoxamine did not produce alterations

53 estricting diffusion of both nutrients (e.g. lactose) and Carbapenems.

54 ccus growth is dependent on the disaccharide lactose, and dietary lactose depletion attenuates Entero

55 saturated fat, excess protein, cholesterol, lactose, and exogenous hormones; and that vulnerable pop

56 rs (for example, maltose, fructose, sucrose, lactose, and galactose) was observed.

57 disaccharides such as galactose, cellobiose, lactose, and galactosyl-glycerol.

58 h a common terminal beta-Gal, including Lec, lactose, and mucin core 2.

59 g a common terminal beta-Gal, including Lec, lactose, and mucin core 2.

60 cued by a supplemental diet rich in calcium, lactose, and phosphate.

61 tolerance is the decreased ability to digest lactose, and the population involved is rapidly increasi

62 s of UHT milk containing different levels of lactose, and the results highlighted the inadequacy of t

63 ysical mixture of the drugs with crystalline lactose, and two spray-dried powders containing the drug

64 Current applications of lactose are insufficient to use the recovered lactose fr

65 We report lactose as a common nutrient that drives expansion of a

66 l, structural and thermal characteristics of lactose as affected by the presence of different acids w

67 g were compared with the same infection with lactose as coaggregation inhibitor.

68 8:1 and C18:2) in IF with higher crystalline lactose as opposed to >40% in others, suggesting a possi

69 le lac induction in the natural setting with lactose as the inducer.

70 Mutants unable to use lactose grew on lactose as the sole carbohydrate when strains with an in

71 ss-over visits to ingest 750 mL milk (37.5 g lactose) as conventional (both A1 and A2 beta-casein) an

72 1), salmeterol xinafoate at 1580 cm(-1), and lactose at 1030 and 1160 cm(-1).

73 he influence of sugars (glucose, sucrose and lactose), at log phase (5 h) and stationary phase (10 h)

74 nsemination (AI), semen was diluted 1:3 in a lactose-based diluent, with 5% EY and glycerol.

75 Infants fed lactose-based formula had the highest levels of glucose

76 e as a potential platform for fabrication of lactose biosensor.

77 formances were favorably compared with other lactose biosensors reported in literature.

78 Third, nonfat milk and lactose blocked the GII.13/21 P domain-glycan binding, w

79 lted in strain-specific growth phenotypes on lactose, but also on a number of mono- and di-saccharide

80 n does not depend on the presence of dietary lactose, but in susceptible individuals, dietary lactose

81 lyse the cleavage of 2'-FL into L-fucose and lactose by constitutively expressing alpha-L-fucosidase.

82 breast milk, during enzymatic hydrolysis of lactose by supplemental beta-galactosidases.

83 tose interactions, whereas the hydrolysis of lactose by the acids plays a smaller role.

84 than plasma glucose to detect LNP following lactose challenge whereas values obtained for urinary ga

85 n lactase persistence (LP) and LNP following lactose challenge with an area under the receiver operat

86 ted varying dairy tolerance underwent a 50-g lactose challenge.

87 commonly expressed in humans; loss of HepII lactose compromises gonococcal fitness in mice.

88 xhibits a pronounced maximum at intermediate lactose concentrations.

89 nd lacY is retained, was employed to disable lactose consumption.

90 that are candidate markers for the intake of lactose-containing foods.

91 ly-Asp insertion impairs bacterial growth in lactose-containing medium and confers a significant in v

92 In these individuals, the consumption of lactose-containing milk and dairy products can lead to t

93 I individuals, LM and digestive comfort with lactose-containing milks was improved with milk containi

94 iosensor was successively tested to quantify lactose content in real milk and cream samples.

95 rt following milk ingestion, irrespective of lactose content or beta-casein type.

96 pared to lactose (sensitivities adjusted for lactose content).

97 had higher milk yield, and fat, protein and lactose contents than controls.

98 rase for catalyzing the cascade reactions of lactose conversion into fructose, producing a lactose-fr

99 of the aged powders showed no occurrence of lactose crystallisation.

100 Inter-relationship between lactose crystallization (LC), the amount and composition

101 nduced the increase of the water activity of lactose crystallization for camel and bovine whey powder

102 elation was observed between surface fat and lactose crystallization in all samples.

103 40% in others, suggesting a possible role of lactose crystallization in preferential migration of tri

104 Lactose crystallization measured by X-ray diffraction ra

105 nsaturated fats in SFF of powders with large lactose crystals and vice-versa.

106 uced apoptosis or stimulated nitric oxide or lactose dehydrogenase production in mature osteoclasts.

107 ent on the disaccharide lactose, and dietary lactose depletion attenuates Enterococcus outgrowth and

108 ce genotype and the postprandial dynamics of lactose-derived metabolites.

109 sed to develop an eco-friendly biosensor for lactose detection.

110 uals, lactose feeding supports the growth of lactose-digesting bacteria in the colon, which enhances

111 significantly improved clinical outcomes for lactose digestion and tolerance.

112 is a potentially useful approach to improve lactose digestion and tolerance.

113 A kinetic study of lactose digestion showed levels of hydrolysis (82.8%) at

114 The development of a noninvasive lactose digestion test based on the measurement of these

115 lation of the colonic bacteria to metabolize lactose effectively is a potentially useful approach to

116 te zeolites can be used for the synthesis of lactose esters, which have potential applications as bio

117 xposes humans to saturated fat, cholesterol, lactose, estrogens, and pathogenic microorganisms, while

118 e and phenotype-specific environmental cues (lactose exposure after weaning) induced changes to epige

119 in mice, recognizes an epitope comprised of lactoses expressed simultaneously from HepI and HepII.

120 intestinal lactase expression with different lactose feeding protocols have consistently shown lack o

121 However, in lactase-deficient individuals, lactose feeding supports the growth of lactose-digesting

122 Relative abundance of lactose-fermenting Bifidobacterium, Faecalibacterium, an

123 When dairy was introduced into the diet, lactose-fermenting Roseburia species increased from day

124 ng dairy products altogether or substituting lactose-free alternatives.

125 containing A2 beta-casein with lactose), or lactose-free conventional milk (LF-CON; containing A1 an

126 nce is a major concern driving the growth of lactose-free foods including lactose-free infant formula

127 The biochemical analyses suggest that the lactose-free formulae may still exceed a carbohydrate lo

128 g the growth of lactose-free foods including lactose-free infant formula.

129 assays and of the HPLC-RI method to analyse lactose-free milk.

130 identified in ultra-high temperature (UHT), lactose-free pasteurized, and lactose-free UHT milk (ULF

131 is has raised the question whether consuming lactose-free products reduces an individual's ability to

132 mptoms to lactose and thus prefer to consume lactose-free products.

133 erature (UHT), lactose-free pasteurized, and lactose-free UHT milk (ULF) and infant formula (IF) usin

134 We tested the hypothesis that a lactose-free, low-carbohydrate F75 milk would serve to l

135 children during the stabilization phase with lactose-free, reduced-carbohydrate milk formula did not

136 Here, four gonococcal LOS mutants, each with lactose from HepII but fixed (unable to phase-vary) LOS

137 actose are insufficient to use the recovered lactose from manufacturing operations.

138 Similarly, withdrawing lactose from the diet does not reduce intestinal lactase

139 lution to lactose intolerance is withdrawing lactose from the diet either by eliminating dairy produc

140 re obtained for pure lactose and 38% for raw lactose from whey.

141 actose conversion into fructose, producing a lactose-fructose syrup (LFS).

142 Lactose (Gal-Glc) from HepII, although phase variable, i

143 dial serum kinetics and urinary excretion of lactose, galactose, galactitol, and galactonate in 14 he

144 Free sucrose, lactose, galactose, glucose and fructose were determined

145 Relevant side chains such as trehalose, lactose, glucose, carboxybetaine, and oligo(ethylene gly

146 nificant difference was detected between the lactose/glucose treatment group and the control.

147 Mutants unable to use lactose grew on lactose as the sole carbohydrate when st

148 stereo-isomer (anomer) mixtures (i.e., alpha-lactose (>=95%, w/w) and beta-lactose (<=4%, w/w)), THz

149 In this study, rates of lactose/H(+) efflux were measured from pH 5.0 to 9.0 in

150 Lactose has become the main byproduct of many dairy prod

151 equence is of consumption of a formula where lactose has been replaced with corn syrup solids (CSS).

152 In both groups, a lactose hydrogen breath test and a lactose tolerance tes

153 Lactose hydrogen breath test and lactose tolerance test

154 The percentage of lactose hydrolysis by the immobilized K. lactis beta-gal

155 metal ions can promote its economic use for lactose hydrolysis in milk.

156 up to 21 reuses and exhibited higher rate of lactose hydrolysis in whey.

157 rformance of the biocatalysts was tested for lactose hydrolysis, and the enzyme immobilized in SiQT10

158 sed in the production of fructose syrup from lactose in a single reaction vessel.

159 been reported in the literature to quantify lactose in dairy products, but the official method of an

160 The hydrolysis of lactose in full-fat or skim milk after 3-week storage re

161 ing electron micrographs showed crystallized lactose in low protein powders at high water activities.

162 during the simulated digestions to hydrolyze lactose in milk more efficiently than free lactase.

163 mics involved in the enzymatic hydrolysis of lactose in milks.

164 During biosynthesis of lactose in the Golgi complex, H(+) is produced as a by-p

165 ource for only certain microbes over GOS and lactose in the simulated gut model.

166 ine antagonist (risperidone), and a placebo (lactose) in three different sessions.

167 intake of galactose, a breakdown product of lactose, increases ovarian toxicity.

168 g/L lactose reduced the RFP intensity due to lactose-induced cytotoxicity.

169 rfering RNA knockdown of Gal-3 in microglia, lactose inhibition of Gal-3 binding, inhibition of neura

170 ferred carbohydrate (glucose or fructose) to lactose, initiation of growth can take several hours, an

171 was mainly due to the manipulation of water-lactose interactions, whereas the hydrolysis of lactose

172 tion over 20%-MgO/SiO(2), converted 99.3% of lactose into a sweetening syrup made of glucose (30.48%)

173 plified a new process for converting aqueous lactose into a sweeting syrup via one-pot synthesis.

174 persistence (LP), which allows digestion of lactose into adulthood and enables the milk-based, high-

175 es are used in the dairy industry to convert lactose into galactooligosaccharides (GOS) that are adde

176 Lactase is an enzyme that hydrolyzes lactose into glucose and galactose in the small intestin

177 tries because it catalyzes the hydrolysis of lactose into glucose and galactose making it useful for

178 Acid-induced hydrolysis of lactose into glucose and galactose varied depending on t

179 a-galactosidase converted 95.77 +/- 0.67% of lactose into glucose and galactose.

180 Nowadays irritable bowel syndrome (IBS) and lactose intolerance (LI) are two very frequent diseases.

181 Lactose intolerance is a major concern driving the growt

182 Lactose intolerance is the decreased ability to digest l

183 The primary solution to lactose intolerance is withdrawing lactose from the diet

184 npersister genotype, which typically confers lactose intolerance, in several different human populati

185 woman had a 2-year history of dyspepsia and lactose intolerance.

186 plements dedicated for people suffering from lactose intolerance.

187 lactose maldigestion and, in certain cases, lactose intolerance.

188 ncluded in the diet of people suffering from lactose intolerance.

189 he level of lactose and to avoid symptoms of lactose intolerance.

190 fort, participants were classified as either lactose intolerant (LI; n = 10, self-reported intolerant

191 o glucose and galactose making it useful for lactose intolerant patients to consume milk and its prod

192 n = 10, self-reported intolerant, diagnosed lactose intolerant), nonlactose dairy intolerant (NLDI;

193 with initial diagnosis of IBS are, instead, lactose intolerant.

194 definitive change in the fecal microbiome of lactose-intolerant individuals, increasing the abundance

195 fically, a yeast strain capable of consuming lactose intracellularly is engineered to produce tagatos

196 Lactose is an abundant dietary carbohydrate metabolized

197 Lactose is an important additive because of its food, ph

198 Lactose is mostly hydrolysed in the small intestine, whe

199 Lactose is obtained as a by-product from whey.

200 er the threshold for intolerance symptoms if lactose is reintroduced into the diet.

201 ork, where the inter-conversion to pure beta-lactose is reported successfully.

202 The data shows that the lactose isomers beta-d-Galp-(1-->2)-d-Glcp, beta-d-Galp-

203 g milk yield (MY), somatic cell score (SCS), lactose (%, LACT), pH and non-casein N (NCN, % of total

204 roic acid production from a mixed substrate (lactose, lactate, acetate, and ethanol).

205 Addition of lactose led to attenuation of bone loss in the capsulate

206 ose substitution of HepI (lactose alone, Gal-lactose, LNnT, or GalNAc-LNnT), were used to define how

207 s (i.e., alpha-lactose (>=95%, w/w) and beta-lactose (<=4%, w/w)), THz s-SNOM resolved local intermol

208 immunization (e.g., by addition of 5% lactose, LTA1, or LT-G33D) minimally altered the develop

209 vasive procedure for diagnosing fructose and lactose malabsorption (FM/LM) but test accuracy and reli

210 Lactose malabsorption (LM) is a major cause of digestive

211 due to low lactase expression, resulting in lactose malabsorption (LM).

212 lamblia and rotavirus infections, secondary lactose maldigestion (LM) might be implicated.

213 caused by genetic programming, that leads to lactose maldigestion and, in certain cases, lactose into

214 veals complex molecular circuits controlling lactose metabolism in S. mutans, where LacR and CcpA int

215 CcpA was also shown to affect lactose metabolism in vivo and to bind to the lacA promo

216 Lactose metabolism presents both classic diauxic behavio

217 have characterized the shift from glucose to lactose metabolism without a classic diauxic lag phase.

218 that catabolize galactose, an end product of lactose metabolism, and of bacteria that metabolize lipi

219 ant individuals, increasing the abundance of lactose-metabolizing bacteria that were responsive to di

220 ose, but in susceptible individuals, dietary lactose might improve intolerance symptoms via colonic a

221 vacrol were emulsified with sodium caseinate-lactose mixture.

222 formation of a strong hydration layer around lactose molecules by hydrogen bonds.

223 Allo-HCT patients carrying lactose-nonabsorber genotypes showed compromised clearan

224 Glycan extensions beyond lactose on HepI modulate binding and function of MAb 2C7

225 d infants were fed formula containing either lactose or CSS-based infant formula and compared with an

226 mptoms of digestive discomfort due to either lactose or differing bovine beta-casein types.

227 Mice gavaged with lactose or fed fructo-oligosaccharides had increased abd

228 We found that oral administration of lactose or fructo-oligosaccharides to mice increases abd

229 tified signatures associated with mice given lactose or fructo-oligosaccharides vs controls.

230 g in the presence of cellobiose, with either lactose or galactosyl-glycerol, revealed initially logar

231 onditions in a system with whey proteins and lactose or glucose.

232 s fertility or that a greater consumption of lactose or low-fat dairy harms fertility.

233 proniosomes by the slurry method, including lactose or maltodextrin as carriers.

234 y cell-surface glycans, starting from either lactose or sucrose as glycosyl donors.

235 ; exclusively containing A2 beta-casein with lactose), or lactose-free conventional milk (LF-CON; con

236 The hydrolysis of lactose over beta-galactosidase converted 95.77 +/- 0.67

237 ostprandial galactitol and galactonate after lactose overload appear to be good proxies for genetical

238 Lactose permease (LacY), a paradigm for the largest fami

239 itution, topology, stability and function of lactose permease are found to have different dependences

240 llar phosphatidylethanolamine lipids, lowers lactose permease folding and reconstitution yields but s

241 Lactose permease is a paradigm for the major facilitator

242 sing a model membrane protein (the bacterial lactose permease LacY reconstituted in proteoliposomes)

243 We found that the lactose permease purified from Escherichia coli cells ex

244 s major facilitator transporter superfamily, lactose permease.

245 taking either donepezil (5 mg) or a placebo (lactose) pill.

246 Their incubation with lactose plus the monosaccharides Gal or Glc resulted in

247 Among lactose polymorphs, anhydrous beta-lactose stands out du

248 Pure beta-lactose powders were synthesized in short reaction time

249 acteria in the colon, which enhances colonic lactose processing and possibly results in the reduction

250 t knowledge regarding the acclimatization of lactose processing in humans.

251 ); for protein (r >= 0.96), fat (r >= 0.99), lactose (r = 0.82) and total solids (r = 0.90).

252 However, the presence of 50 g/L lactose reduced the RFP intensity due to lactose-induced

253 n-synonymous transcription factors using the lactose repressor topology as a guide.

254 d modulate the DNA-binding activities of the lactose repressor.

255 The fourth mutant (Gal-lactose) resisted direct complement-dependent killing bu

256 (92.9%) and a2 Milk(TM) (78.6%) compared to lactose (sensitivities adjusted for lactose content).

257 ycerol (2, 5 or 10%), diluent types (SHOTOR, lactose, skim milk or INRA-96(TM)), freeze rates (2, 4 o

258 The overall mean fat, protein, lactose, solids-not-fat, and total solids concentrations

259 and thermal characteristics of concentrated lactose solutions containing 0.05, 1, or 4% (w/w) of thr

260 s hindered evaporation of water from most of lactose solutions.

261 Among lactose polymorphs, anhydrous beta-lactose stands out due to its thermodynamic stability.

262 Using crystalline-lactose stereo-isomer (anomer) mixtures (i.e., alpha-lac

263 coccal mutants with glycan extensions beyond lactose-substituted HepI (lactose alone, LNnT, or GalNAc

264 e-vary) LOS HepI glycans extended beyond the lactose substitution of HepI (lactose alone, Gal-lactose

265 agnostic threshold may vary depending on the lactose substrate or the composition of the milk.

266 xchange for H(+) to sustain the functions of lactose synthase and potentially other glycosyl-transfer

267 isorders in MGs of lactating goats, shifting lactose synthesis to acute fermentative glycolysis which

268 ealthy young women were challenged with 50 g lactose then randomized for separate cross-over visits t

269 larly is engineered to produce tagatose from lactose through three layers of manipulations.

270 Recoveries ranged from 93% for lactose to 98% for glucose and galactose.

271 the inter-conversion from monohydrate alpha-lactose to anhydrous beta-lactose was investigated emplo

272 e powders caused glass transition signals of lactose to evolve, although the powders exhibited a slig

273 formula (IMF) powders prepared with various lactose-to-maltodextrin (L:M) ratios (L:M 100:0, L:M 85:

274 leotide polymorphism that is associated with lactose tolerance and milk intake.High consumers of nonf

275 groups, a lactose hydrogen breath test and a lactose tolerance test were performed after exclusion of

276 Lactose hydrogen breath test and lactose tolerance test were positive in all 7 patients (

277 blood glucose, and urinary galactose after a lactose tolerance test.

278 like light eyes, hair, and skin, as well as lactose tolerance, can be traced back to the Bronze Age

279 ously associated with lactase expression and lactose tolerance, had higher dietary vitamin D intake a

280 farming by humans favored alleles for adult lactose tolerance.

281 n = 20, self-reported intolerant, diagnosed lactose tolerant), or dairy tolerant (DT; n = 10, self-r

282 T; n = 10, self-reported tolerant, diagnosed lactose tolerant).

283 rs, the osmosensing transporter ProP and the lactose transporter LacY.

284 ictions based on computational models of the lactose uptake pathway remain controversial.

285 than an all-or-none response in the natural lactose uptake system.

286 olid meal were investigated by MRI and (13)C-lactose-ureide breath test.

287 The calibration curve of lactose using optimized parameters shows a wide linear m

288 ity, a greater consumption of phosphorus and lactose was associated with slightly higher fecundabilit

289 monohydrate alpha-lactose to anhydrous beta-lactose was investigated employing a methanolic solution

290 ified, while the influence of glycation with lactose was limited.

291 No residual lactose was observed after 90 day.

292 h biofilms treated with sucrose, glucose and lactose, we confirmed that this model can reproduce the

293 redominant phyla regulated by 2'-FL, GOS and lactose were significant increase in Firmicutes, numeric

294 oscopy confirmed the presence of crystalline lactose which significantly (p < 0.05) increased the pow

295 ed yeast produces 37.69 g/L of tagatose from lactose with a tagatose and galactose ratio of 9:1 in th

296 0.74 mol/kg fructose and 0.17 or 0.19 mol/kg lactose with an enzymatic activity of 2.0 or 2.8 mukat/k

297 s were synthesized via the esterification of lactose with lauric acid in different organic solvents w

298 PS increased milk protein and decreased milk lactose, with more marked changes in HS goats.

299 C57Bl/6 mice were gavaged with lactose, with or without the antiglycation agent pyridox

300 For these individuals, lactose withdrawal results in the loss of colonic adapta