ライフサイエンスコーパス: lamina cribrosa

1 ased thinning and posterior curvature of the lamina cribrosa.

2 tinal layers, optic nerve head, choroid, and lamina cribrosa.

3 ost were located immediately anterior to the lamina cribrosa.

4 umatically induced optic nerve damage at the lamina cribrosa.

5 issues, such as the peripapillary sclera and lamina cribrosa.

6 reactivity, and increased thickening of the lamina cribrosa.

7 nt visualization of the choroid, sclera, and lamina cribrosa.

8 st posterior to the retina, analogous to the lamina cribrosa.

9 ts contribution to increased rigidity of the lamina cribrosa.

10 nally passing through the full extent of the lamina cribrosa.

11 erfusion of the neurons as they traverse the lamina cribrosa.

12 anent) and hypercompliant deformation of the lamina cribrosa and anterior scleral canal wall are pres

13 The anterior lamina cribrosa and its continuity with the prelaminar g

14 e-dependent effects cause bowing back of the lamina cribrosa and optic disc cupping.

15 thinning, stretching, and deformation of the lamina cribrosa and peripapillary sclera that are minima

16 d the anterior and posterior surfaces of the lamina cribrosa and peripapillary sclera were delineated

17 e scleral foramen (the mouse does not have a lamina cribrosa), and exited the inferior retrobulbar op

18 of the dura mater toward the jugular fossa, lamina cribrosa, and perineurium of the cranial nerves t

19 abled improved visualization of the choroid, lamina cribrosa, and sclera.

20 In the lamina cribrosa, ANGPTL7 expression was associated with

21 rmanent posterior deformation of the central lamina cribrosa, as well as expansion of the anterior an

22 authors aimed to study the potential role of lamina cribrosa astrocytes as a component of activated i

23 Although activation of lamina cribrosa astrocytes has been identified in glauco

24 by IL-10 was approximately 6 times higher in lamina cribrosa astrocytes incubated under simulated isc

25 gamma induced HLA-DR expression in brain and lamina cribrosa astrocytes, up to 25-fold, (P < 0.001) e

26 rogresses along the optic nerve to reach the lamina cribrosa by P34, coincident with the time of eye

27 ng the retinal schisis cavity and gap in the lamina cribrosa corresponding to the optic pit.

28 intracranial pressure (ICP) at the level of lamina cribrosa could have important implications for un

29 studied using SS-OCT, including the anterior lamina cribrosa curvature, anterior lamina cribrosa dept

30 A focal lamina cribrosa defect (LCD) was found in four eyes (4 p

31 e anomalies is the presence of a scleral (or lamina cribrosa) defect permitting anomalous communicati

32 ribrosa insertions, laminar thickness, focal lamina cribrosa defects (FLCDs), and lamina cribrosa mic

33 Focal lamina cribrosa defects appear more commonly in glaucoma

34 nd all LC parameters such as cup depth (CD), lamina cribrosa depth (LCD), prelaminar tissue thickness

35 In glaucoma patients, lamina cribrosa depth changes are detected with similar

36 To determine whether: (1) change in lamina cribrosa depth occurs more frequently than change

37 Lamina cribrosa depth should be measured from an anterio

38 Lamina cribrosa depth was larger in POAG eyes as compare

39 anterior lamina cribrosa curvature, anterior lamina cribrosa depth, anterior lamina cribrosa insertio

40 The authors predicted the lamina cribrosa displacement (LCD), scleral canal expans

41 To estimate the pressures at the lamina cribrosa, geometrical distances were estimated fr

42 he translaminar pressure gradient across the lamina cribrosa, has been reported in glaucoma patients.

43 The diagnostic utility of SS-OCT for lamina cribrosa imaging is promising, but standardized n

44 he major lysyl oxidase isoform in the normal lamina cribrosa in association with a complex elastic fi

45 disc drusen and their relationship with the lamina cribrosa in vivo.

46 ifically within the peripapillary sclera and lamina cribrosa) in response to intraocular pressure (re

47 there is posterior migration of the anterior lamina cribrosa insertions as well as increased thinning

48 re, anterior lamina cribrosa depth, anterior lamina cribrosa insertions, laminar thickness, focal lam

49 Posterior migration of the lamina cribrosa is a component of early cupping in monke

50 brosa using SS-OCT has demonstrated that the lamina cribrosa is likely biomechanically active and tha

51 ss, strain, and geometric deformation of the lamina cribrosa (LC) and peripapillary sclera.

52 everity are associated with the shape of the lamina cribrosa (LC) as measured by a global shape index

53 ogeneous material properties defined for the lamina cribrosa (LC) based on local connective tissue vo

54 e associated alterations in the phenotype of lamina cribrosa (LC) cells are implicated in changes occ

55 human optic nerve head (ONH) astrocytes and lamina cribrosa (LC) cells express BMP and BMP receptor

56 g the potential clinical importance of focal lamina cribrosa (LC) defects as a characteristic structu

57 The properties of the lamina cribrosa (LC) greatly influenced its response to

58 gions comparable to the human prelaminar and lamina cribrosa (LC) in the optic nerve head and the ret

59 or glaucoma, and pathological changes in the lamina cribrosa (LC) may play a leading role.

60 essel shift inside the ONH occurs within the lamina cribrosa (LC) or the prelaminar tissue.

61 pilla), circumpapillary choroidal thickness, lamina cribrosa (LC) parameters, and peripapillary scler

62 CO shift, peripapillary choroidal thickness, lamina cribrosa (LC) parameters, prelaminar thickness, a

63 We assessed in vivo lamina cribrosa (LC) position within the optic nerve hea

64 an increased pressure difference across the lamina cribrosa (LC) related to a low intracranial press

65 examiners masked to patients clinical data: lamina cribrosa (LC) thickness and area, prelaminar neur

66 (OCTA) were used to determine the status of lamina cribrosa (LC), peripapillary retinal nerve fiber

67 Deep ONC structures, including the lamina cribrosa (LC), short posterior ciliary artery (SP

68 y segmented (prelamina, choroid, sclera, and lamina cribrosa [LC]).

69 , focal lamina cribrosa defects (FLCDs), and lamina cribrosa microarchitecture.

70 visualization of the porous structure of the lamina cribrosa, nerve fiber layer, choroid, photorecept

71 ared with normal contralateral controls, the lamina cribrosa of eyes with elevated IOP exhibited mark

72 border tissue of Elschnig, Bruch's membrane, lamina cribrosa, optic nerve septa, pial sheath, and vas

73 with posterior displacement of the anterior lamina cribrosa over time.

74 The ability to consistently resolve lamina cribrosa pores in vivo has applications in the st

75 luate the changes in choroidal thickness and lamina cribrosa position after nonpenetrating deep scler

76 l thickness, prelaminar tissue thickness and lamina cribrosa position before and 7 days and 1 month a

77 atients regarding visual acuity, refraction, lamina cribrosa position, ganglion cell layer volume, or

78 the ONH tissues in all 17 monkeys, anterior lamina cribrosa position, laminar thickness, and scleral

79 y between retinal schisis and the gap in the lamina cribrosa present in the optic disc pit, supportin

80 Trans-lamina cribrosa pressure difference (TLCPD) was calculat

81 The trans-lamina cribrosa pressure difference (TLCPD) was calculat

82 The trans-lamina cribrosa pressure difference was calculated in 2

83 ressure, leading to an abnormally high trans-lamina cribrosa pressure difference, could result in bar

84 iven that the biomechanics of the sclera and lamina cribrosa probably influence retinal ganglion cell

85 udoexfoliation-specific elastinopathy of the lamina cribrosa resulting from a primary disturbance in

86 y the anterior and posterior surfaces of the lamina cribrosa, scleral flange, and peripapillary scler

87 E), neural canal opening (NCO), and anterior lamina cribrosa surface (ALCS) by using custom software.

88 um, neural canal opening (NCO), and anterior lamina cribrosa surface (ALCS) were delineated using cus

89 The mean anterior lamina cribrosa surface depth (ALCSD) and choroidal thic

90 and the ONH surface depth (ONHSD), anterior lamina cribrosa surface depth (ALCSD), and prelaminar ti

91 g (BMO) area, mean cup depth (MCD), anterior lamina cribrosa surface depth (ALCSD), prelaminar tissue

92 iridocorneal angle, posterior bowing of the lamina cribrosa, swelling and loss of large retinal gang

93 laminar deformation, neural canal expansion, lamina cribrosa thickening, and posterior (outward) bowi

94 Compared with normal and POAG specimens, lamina cribrosa tissues obtained from early and late sta

95 Imaging of the lamina cribrosa using SS-OCT has demonstrated that the l

96 The anterior lamina cribrosa was consistently imaged in vivo in norma

97 Compared with the regional PID maximums, the lamina cribrosa was posteriorly deformed centrally, infe

98 s of the eight monkeys with IOP 0 mm Hg, the lamina cribrosa was posteriorly displaced and thicker an

99 Within the high-IOP early-glaucoma eyes, the lamina cribrosa was posteriorly displaced and thicker an

100 Within the high-IOP normal eyes, the lamina cribrosa was posteriorly displaced compared with

101 Reflectance images (840 nm) of the anterior lamina cribrosa were acquired using the AOSLO in four or

102 eripapillary sclera, scleral canal wall, and lamina cribrosa were present among the three normal eyes

103 Different aspects of the lamina cribrosa were studied using SS-OCT, including the

104 iliary muscle, corneoscleral fibroblast, and lamina cribrosa) were cultured in 24-well plates in the

105 eyes, elastin appeared as fine fibers in the lamina cribrosa, without elastotic aggregates, and witho