ライフサイエンスコーパス: laminar flow

1 ional bilayer patterning techniques, such as laminar flow.

2 n of CD59 expression in response to arterial laminar flow.

3 d the time scale for the re-establishment of laminar flow.

4 is translocated within cells in response to laminar flow.

5 le or individual patterns was achieved using laminar flow.

6 Grx1 is markedly up-regulated by the steady laminar flow.

7 d 4 agonists in an in vitro model of chronic laminar flow.

8 fusion between parallel streams of liquid in laminar flow.

9 ased on the band broadening of a solute in a laminar flow.

10 ells [LECs]) were exposed to low-rate steady laminar flow.

11 s at low Reynolds numbers to ensure entirely laminar flow.

12 pecies to interfaces within the capillary by laminar flow.

13 as 4-fold more monocytes than T cells under laminar flow.

14 bes and examined during abrupt reductions in laminar flow.

15 odel for mass transfer to a flat plate under laminar flow.

16 d of ECs that are exposed to continuous high laminar flow.

17 is based on band broadening of a sample in a laminar flow.

18 stribution in particle velocities due to the laminar flow.

19 astic sphere in a viscous fluid under steady laminar flow.

20 induced by disturbed flow but not by steady laminar flow.

21 ltures grown under controlled and continuous laminar flow.

22 ccurate manner in microchannels experiencing laminar flows.

23 and clogging at flow intersections, even in laminar flows.

24 Two chips with laminar flow (0 degrees filament direction) or mixing fl

25 vein endothelial cells (HUVECs) subjected to laminar flow (10 dyne/cm2) in a parallel-plate flow cham

26 The application of a laminar flow (12 dyn/cm2) increased the deacetylation at

27 fined as the smallest connection between the laminar flow acceleration zone and the turbulent regurgi

28 d within 0.5-1.0 mm of the oocyte to provide laminar flow across the oocyte surface.

29 low channel with cultured ECs, we found that laminar flow activated the PPARgamma-mediated PPAR-respo

30 r study identified a molecular mechanism for laminar flow-activated LEC proliferation.

31 poxygenases (CYP450s) were able to block the laminar flow-activated PPARgamma.

32 We demonstrate that exposure of EC to laminar flow activates ARE-mediated transcriptional acti

33 Laminar flow activates endogenous PPARgamma in ECs, whic

34 nvestigated the molecular mechanism by which laminar flow activates p53 and p21Waf1 in endothelial ce

35 We previously reported that laminar flow activates peroxisome proliferator-activated

36 Furthermore, laminar flow activation of antioxidant genes via an ARE-

37 ive interactions in both nonstatic shear and laminar flow adhesion assays.

38 fective membrane materials are replaced with laminar flow and a nonselective, porous convection barri

39 The new tube cell is based on a constant laminar flow and a well-controlled delivery of the laser

40 p, whose transcription is in turn induced by laminar flow and APLN/APLNR signalling.

41 xperiments with endothelial cells exposed to laminar flow and cocultured with pericytes confirmed tha

42 In the arterial endothelium, laminar flow and cyclical stretch induce expression of N

43 n excised whiskers in a flume in response to laminar flow and disturbed flow.

44 is work illustrates the feasibility of using laminar flow and electrokinetic forces for the efficient

45 ood flow and low fluid shear stress, whereas laminar flow and high fluid shear stress are athero-prot

46 ent flow and low fluid shear stress, whereas laminar flow and high shear stress are atheroprotective.

47 ta show that BMK1 can be activated by steady laminar flow and is atheroprotective by preventing endot

48 ow show that JNK activation by both onset of laminar flow and long-term oscillatory flow is matrix-sp

49 rms of microfluidic technology, single-phase laminar flow and multiphase microfluidics.

50 lated kinase 5 (ERK5) is activated by steady laminar flow and regulates EC function by increasing end

51 rences in the rates of chemical reactions in laminar flow and segmented flow systems are also compare

52 The same feed flow rate was used in both the laminar flow and segmented flow systems.

53 ptor-gamma (PPARgamma) in ECs in response to laminar flow and the associated antiinflammatory effect.

54 dothelial cell cultures that, due to lack of laminar flow and the growth of the cells on non-complian

55 of the hydrodynamic force produced from the laminar flow and the magnetophoretic force produced from

56 principle, we used the coupled microfluidic laminar flow and time-resolved two-photon excitation mic

57 In conjunction with laminar flows and fluorescence, we also show precise con

58 rom patients with AAA from peripheral sites (laminar flow) and from inside the aneurysm segment (turb

59 t makes use of the asymmetric bifurcation of laminar flow around obstacles.

60 Laminar flow arrests vascular endothelial cells at the G

61 at increasing the force perpendicular to the laminar flow as described here is broadly applicable to

62 expressing the wild-type C-cadherin using a laminar flow assay on substrates coated with CEC 1-5.

63 In laminar flow assays, lymphoid cells specifically roll on

64 its use as an indicator of reagent mixing in laminar-flow assays carried out in microfluidic devices.

65 Furthermore, laminar flow augmented cellular levels of EETs but decre

66 oach described when compared to conventional laminar flow-based fluidics.

67 us/nonaqueous immiscible solvent-based RFBs; laminar flow-based RFBs; single-phase co-laminar flow ba

68 also presented to guide the design of future laminar flow batteries.

69 Bs; laminar flow-based RFBs; single-phase co-laminar flow batteries; liquid/solid membrane-free RFBs;

70 e report on a membrane-less hydrogen bromine laminar flow battery as a potential high-power density s

71 wer density achieved by the hydrogen bromine laminar flow battery, along with the potential for recha

72 n microchannels under the combined effect of laminar flow, Brownian motion and electrophoretic drift,

73 therosclerosis protective genes under steady laminar flow but not under oscillatory flow) is a conseq

74 es cell adhesion under dynamic conditions of laminar flow, but not under static conditions was signif

75 rticles were deflected from the direction of laminar flow by a perpendicular magnetic field depending

76 The compact system was readily housed in a laminar flow cabinet allowing an ISO class-5 environment

77 Mass transport in laminar flow can improve the electrochemiluminescence (E

78 Laminar flows can produce particle trajectories that are

79 Laminar flow caused a transient activation of both AMPK

80 obodies targeting two different epitopes and laminar flow chamber assay to measure the association an

81 dothelial cells exposed to shear stress in a laminar flow chamber or treated with Ca2+ ionophores in

82 We used a laminar flow chamber to measure, first, 2D TCR-pMHC diss

83 Here, we used a laminar flow chamber to monitor at the single molecule l

84 human umbilical vein endothelial cells in a laminar flow chamber, RBC phthalate density profiles, me

85 er static conditions and in a parallel plate laminar flow chamber.

86 immunofluorescence microscopy coupled with a laminar flow chamber.

87 rapid movement of trapped molecules between laminar flow channels and a flow-free reservoir.

88 that serves as a barrier between two stacked laminar-flow channels: one containing the cell culture a

89 This tandem turbulent-laminar flow chromatographic system in a total cycle tim

90 While low-rate laminar flow commonly induces the classic shear stress r

91 ultured in a dynamic microfluidic chip under laminar flow compared to the static culture condition.

92 lops preferentially at sites where disturbed laminar flow compromises endothelial cell (EC) function.

93 of the sample to the reagents under a strict laminar flow condition synergistically improved the repr

94 .d.) at a speed approximately 20 cm/s, under laminar flow conditions (Re approximately equal to 14).

95 the behavior of protein nanostructures under laminar flow conditions and their assembly mechanism int

96 trated by their binding to brain cells under laminar flow conditions as well as their enhanced transp

97 d to study lymphocyte adhesion under defined laminar flow conditions in transduced HUVEC monolayers.

98 s important to be able to reproducibly model laminar flow conditions in vitro.

99 important situations in which ECs experience laminar flow conditions in vivo, such as along long stra

100 ol particles through cylindrical tubes under laminar flow conditions using explicit analytical equati

101 Under laminar flow conditions, a redox reaction can be driven

102 ronan on endothelial cells under physiologic laminar flow conditions, and have proposed that this int

103 lity to move reagents through channels under laminar flow conditions, and the capacity to precisely p

104 coated microposts under precisely controlled laminar flow conditions, and without requisite pre-label

105 Under laminar flow conditions, Doshi et al. have shown that fo

106 Under laminar flow conditions, the makeup flow confines the sa

107 Under laminar flow conditions, when no external forces are app

108 It operates under laminar flow conditions, which requires that the time be

109 urine leukocytes to adherent platelets under laminar flow conditions.

110 coli biofilms was analyzed under static and laminar flow conditions.

111 n of CD4+ CD45RO+ memory T lymphocytes under laminar flow conditions.

112 rcially available peristaltic pumps to study laminar flow conditions.

113 cell debris is simultaneously removed using laminar flow conditions.

114 oadening of an analyte under well-controlled laminar flow conditions.

115 performing redox cycling measurements under laminar flow conditions.

116 rryover compared with results obtained under laminar-flow conditions.

117 sibly be used for bio-inspired surfaces as a laminar flow control means.

118 entrations was made possible by carrying out laminar flow-controlled dilution on-chip.

119 cells (ECs) align poorly, whereas sustained laminar flow correlates with cell alignment in the direc

120 contamination of a syringe pump outside the laminar-flow curtain of a patient who was admitted with

121 eas in areas of fully developed, undisturbed laminar flow, Cx43 expression returned to control levels

122 helial cells indicated that atheroprotective laminar flow decreased Tie1 expression in vitro.

123 f an individual laminar stream in multiphase laminar flow depends on the lateral position of the stre

124 The laminar flow deposition process (LFD) used to form two-d

125 significant adhesive activity when tested in laminar flow detachment assays and aggregation assays.

126 Laminar flow develops across the AV canal at 20-30 hpf,

127 pendent biochemical reaction conditions in a laminar flow device.

128 quent studies revealed that atheroprotective laminar flow downregulated the level of miR-92a precurso

129 electrolyte solvents and the engineering of laminar flow dynamics to achieve efficient electrolyte s

130 We demonstrated that laminar flow enhanced ES cell-derived progenitor cell pr

131 These observations support that, for laminar flows, erosion is a dynamical phase transition t

132 unit, and existence of operating rooms with laminar flow exhaust systems.

133 events in multivariate models was the use of laminar flow exhaust systems.

134 We found, firstly, that laminar flow fails to overcome the inflammatory effects

135 quantification of the penetration depth of a laminar flow field (i.e., the slip length) in a densely

136 A laminar flow forced convection model was used in the des

137 Under defined laminar flow from 1.5 to 0.5 dyne/cm2, the adenovirus ve

138 pray capillary are mitigated by the use of a laminar-flow gas with the aid of a flow diffuser.

139 onditions (pH 3.7) in a confined single-pass laminar-flow geometry.

140 While the physics behind laminar flows has been studied for 200 years, understand

141 Regions in the vasculature exposed to steady laminar flow have a lower likelihood for atherosclerosis

142 The hydrodynamics of laminar flow in a microfluidic device has been used to c

143 (+) are in agreement with those expected for laminar flow in a tubular electrode geometry.

144 g that turbulent flow is more favorable than laminar flow in detecting the VOCs in water.

145 Contrary to laminar flow in most microfluidics, we find that the flo

146 ion of aneurysm exclusion and restoration of laminar flow in successful cases.

147 steriorly oriented cilia driving a leftwards laminar flow in the embryonic node, thereby activating a

148 Steady laminar flow in the straight parts of the arterial tree

149 active index gradient (RIG) between adjacent laminar flows in a microfluidic device has been used to

150 ients of proteins with complex shapes, using laminar flows in microchannels.

151 ods, including evaporating sessile droplets, laminar flows in microfluidics or electrochemistry.

152 nches and curved regions are proatherogenic, laminar flows in the straight parts are atheroprotective

153 studies on fluid dynamic characteristics of laminar flows in widening microchannels and hydrodynamic

154 The application of laminar flow increased SIRT1 level and activity, mitocho

155 Laminar flow increased SIRT1-eNOS association and eNOS d

156 Laminar flow increased the activity of histone deacetyla

157 We found that laminar flow induced SP1 serine phosphorylation by prote

158 Steady laminar flow induced the classic shear stress responses

159 Laminar flow induced the GAL-PPARgamma-LBD fusion protei

160 F292 in endothelial cells in vitro abolished laminar flow-induced alterations in cell orientation, pa

161 of the SDOS-cZNF292 binding site, prevented laminar flow-induced cytoskeletal reorganization thereby

162 regulated ERK5 transcriptional activity and laminar flow-induced endothelial nitric oxide synthase e

163 TNFalpha inhibited the steady laminar flow-induced eNOS expression, and this effect wa

164 data reveal a molecular mechanism underlying laminar flow-induced lymphatic sprouting.

165 m either the NQO1 or HO-1 promoter abolished laminar flow-induced NQO1 and HO-1 transcriptional activ

166 ic inhibitor of Nrf2 (Keap1/INrf2) inhibited laminar flow-induced NQO1 promoter activation in EC.

167 nced, but overexpression of sEH reduced, the laminar flow-induced PPARgamma activity.

168 mechanotransduction pathway that translates laminar flow-induced shear stress to activation of lymph

169 In contrast, exposure to arterial laminar flow induces a gene program that confers a large

170 Steady laminar flow inhibited both TNF activation of ASK1 and J

171 We hypothesized that steady laminar flow inhibits cytokine-mediated activation of MA

172 of steady laminar flow, we hypothesized that laminar flow inhibits proinflammatory cytokine-mediated

173 A heated (approximately 90 degrees C) laminar flow interface has been designed to assist in th

174 sults suggest that BMK1 activation by steady laminar flow is atheroprotective by inhibiting EC apopto

175 Steady laminar flow is atheroprotective, in part because of its

176 Unidirectional laminar flow is atheroprotective, in part by inhibiting

177 low Reynolds numbers (less than 10(2)) where laminar flow is expected, H/D exchange kinetics were wel

178 ccurs on the millisecond time scale and that laminar flow is re-established on a 50-ms time scale.

179 er and the functionalized surface, created a laminar flow junction with a resulting reaction volume o

180 size variance, and may be operated up to the laminar flow limit for high throughput vesicle productio

181 The combination of co-existing laminar flow manipulation and hydrodynamic single-cell t

182 ction represents a mechanism by which steady laminar flow may exert atheroprotective effects on the e

183 cterial cells immobilized in the center of a laminar-flow microfluidic channel, where they are expose

184 Using a microfluidic laminar flow mixer designed for studies of protein foldi

185 uilibrium, we have coupled a microfabricated laminar-flow mixer to a confocal optical system.

186 We then employ ultrafast laminar-flow mixing experiments to study the folding kin

187 Using an in vitro laminar flow model, we have demonstrated tethering and f

188 , however, suggested that this held only for laminar flow, not for regurgitant jets, in which turbule

189 olecular transport (mixing) between adjacent laminar flows occurs by molecular diffusion between flow

190 tching and resolved chromatographically at a laminar flow of 2 mL/min.

191 This model calculates the laminar flow of analyte within the flow cell, its diffus

192 ere, we show that ependymal cilia generate a laminar flow of cerebrospinal fluid through the cerebral

193 This paper describes the use of laminar flow of liquids in capillary systems to pattern

194 and attached to a glass slide, after which a laminar flow of lysis buffer extends the lysed chromatin

195 We previously found that laminar flow of short duration inhibited tumor necrosis

196 ructure and function depend on a continuous, laminar flow of the core and cladding liquids.

197 ent collapse within the channel disrupts the laminar flow of the parallel fluid streams and produces

198 Laminar flow of the separated particles to downstream co

199 icrofluidic channels containing the parallel laminar flow of two fluids.

200 wn abolishes the inhibitory effect of steady laminar flow on Bim.

201 This study aims to elucidate the role of laminar flow on embryonic stem (ES) cell differentiation

202 The effects of laminar flow on endothelial membrane potential were stud

203 used in combination with either multistream laminar flow or photolithography to pattern surface free

204 SAMs) in combination with either multistream laminar flow or photolithography.

205 The laminar flow pattern was achieved using a plain wide T-j

206 all reflectance and Doppler images, a clear laminar flow pattern was observed, with v(max) appearing

207 ted by diffusion and is much slower with the laminar flow pattern, whereas the reaction is completed

208 se three mycotoxins was demonstrated via the laminar flow patterning of probes in an area of approxim

209 nd continuity were first solved to determine laminar flow patterns of odorous air at quiet breathing

210 f this technique is the use of deterministic laminar flow patterns to precisely transport a reacted s

211 ayer, inducing a transition from swirling to laminar flow patterns while maintaining a constant migra

212 ical vein endothelial cells (HUVEC) grown on laminar-flow perfusion channels were stimulated with 1 m

213 es particles through water condensation in a laminar flow, permitting inertial collection into the mi

214 and thromboxane B(2) biosynthesis and under laminar flow platelet-dependent thrombus growth in SARS-

215 present a new microfluidics-assisted robust laminar-flow process, which allows for the generation of

216 s below a threshold that interferes with the laminar flow profile or detector signals.

217 s a microfluidic technique that utilizes the laminar flow profile to continuously separate particles

218 Conversely, laminar flow protects against endothelial dysfunction, a

219 evelop in regions of disturbed flow, whereas laminar flow protects from atherogenesis; however, the m

220 ed in a small size flow channel at different laminar flow rates.

221 ude is slower than the velocity under steady laminar flow regime for the same value of the Peclet num

222 stems provide, they typically operate in the laminar flow regime under mass transfer limitations, whe

223 ntinuous culture flow cell (a controlled low laminar flow regime with Reynolds number ~ 1).

224 Plug flow and laminar flow regimes were considered.

225 ansport on the parabolic velocity profile of laminar flow remain unknown.

226 showed that AMPK, by counteracting Akt under laminar flow, resulted in a transient activation of S6K.

227 the vessel, the endothelial cells experience laminar flow, resulting in endothelial cell alignment in

228 As blood transitions from steady laminar flow (S-flow) in healthy arteries to disturbed f

229 g flows, long analyzed according to accepted laminar flow scission theories, were in fact affected by

230 After continuous laminar flow shear stresses, all cells gradually elongat

231 ic endothelial cells subjected to continuous laminar flow shear stresses.

232 astructures were different when generated by laminar flow shear versus shaking/stirring.

233 We found here that laminar flow (shear stress = 12 dynes/cm2) rapidly stimu

234 MK1, bovine aortic EC were exposed to steady laminar flow (shear stress = 12 dynes/cm2).

235 to prolonged physiological levels of steady laminar flow (shear stress = 20 dyn/cm(2)) in endothelia

236 eexposure of BLMVECs to physiological steady laminar flow (shear stress=12 dyne/cm2) for 10 minutes s

237 In this study, we found that laminar flow (shear stress=12 dyne/cm2) rapidly activate

238 ese results, S4-depleted HUVECs in long-term laminar flow showed increased activation of proinflammat

239 Laminar flow spectroelectrochemistry (LF-SEC) is therefo

240 Laminar flow stabilized and activated histone deacetylas

241 e microelectrode array essentially along the laminar flow streamlines.

242 particles are deflected through alternating laminar flow streams of reagents and washing solutions v

243 Ex vivo laminar flow studies with human blood demonstrated BP-PO

244 In contrast, the athero-protective laminar flow suppressed YAP/TAZ activities.

245 drag and fuel consumption for aircraft with laminar-flow surfaces.

246 were deflected further from the direction of laminar flow than the 2.0-microm magnetic particles.

247 reach a mature morphology and acquire high, laminar flow that down-regulates DACH1.

248 istinct from that elicited by nonatherogenic laminar flow, the mechanisms involved are poorly underst

249 Because of laminar flow, there is no bulk mixing of the fluids in t

250 l was constructed to provide well-controlled laminar flow through a glass capillary for assessment by

251 Passing a laminar flow through a short illuminated section of a mi

252 y region near the walls of a pressure-driven laminar flow through an empty microchannel.

253 ipoprotein, but confined by atheroprotective laminar flow through an upregulation of microRNA (miR)-1

254 drodynamic regimes (turbulent batch mode and laminar flow-through recirculation mode), optical thickn

255 This system maintains a 10 microm thick laminar-flow-through biofilm system that minimizes both

256 Elevated laminar flow, TNFalpha and cigarette smoke extract syner

257 -phase photopolymerization, lithography, and laminar flow to allow the creation of complex and autono

258 erizing microfluidic flow profiles from slow laminar flow to fast near-turbulent flow.

259 The technique exploits multistream laminar flow to selectively expose cells to different en

260 x generation upon the transition from smooth laminar flows to turbulence is generally accompanied by

261 Droplet evaporation in a laminar flow tube was measured in a Tandem Differential

262 therogenesis, whereas regions of undisturbed laminar flow (UF) appear protected.

263 , but much less at regions of unidirectional laminar flow (UF).

264 elial cell lysate (which is unretained), and laminar flow valving to direct the male and female fract

265 nt spleen cell migration under 2 dynes/cm(2) laminar flow was blocked by pretreatment of endothelial

266 The regulation of the p53-p21Waf1 pathway by laminar flow was further supported by observations that

267 Laminar flow was present in all the examples.

268 acy, and suitability for mass manufacturing; laminar flow was studied to assess their suitability for

269 Diffusive transport coupled with laminar flow was used to control the concentration and e

270 osclerosis is decreased in regions of steady laminar flow, we hypothesized that laminar flow inhibits

271 HCAECs under chronic laminar flow were found to be normally responsive to lip

272 e, or triple molecular DNA layers within the laminar flows were obtained according to the average loc

273 of cell attachment to a glass surface under laminar flow, whereas coordinate, low-level overexpressi

274 Regions of the arterial tree exposed to laminar flow, which exerts high shear stress, are protec

275 CO(2), visual, and olfactory stimuli using a laminar flow wind tunnel.

276 teries where ECs experience atheroprotective laminar flow with high shear stress.

277 The laminar flow with negligible ionic diffusion between dif

278 nematics, is in this way regularized into a laminar flow with periodic velocity oscillations.

279 icient mixing between streams, (ii) multiple laminar flows with minimal mixing between streams, and (

280 in situ, at the liquid junction between two laminar flows within the microfluidic channel.