ライフサイエンスコーパス: laminarin

1 elfish uptake of polysaccharides, except for laminarin.

2 lucanase activity on the beta-1,3-1,6-glucan laminarin.

3 ilar activities compared to those of natural laminarin.

4 gy adapted to efficient degradation of algal laminarin.

5 ibited by the soluble beta-glucan antagonist laminarin.

6 ntage was further reduced in the presence of laminarin.

7 on of Syk and this response was inhibited by laminarin.

8 pull-down with the biotinylated beta-glucan laminarin.

9 Laminarin (0.1%) enhances expression after 18 h and othe

10 ere cultured with soluble chitin, mannan, or laminarin (a polymer of beta-glucan), 1 to 10 microm bet

11 lucose homopolymer] but was not inhibited by laminarin [a beta(1-->3)-linked glucose homopolymer].

12 The carboxyl-terminal domain bound to laminarin, a beta-1,3-glucan with beta-1,6 branches, but

13 Laminarin, a beta-1,3-glucan, presented two classes of b

14 Laminarin, a beta-glucan ligand of Dectin-1, was incorpo

15 However, addition of laminarin, a glucose polysaccharide (~6 kDa) containing

16 rom Manduca sexta betaGRP2 (N-betaGRP2) with laminarin, a soluble form of beta-1,3-glucan.

17 lucan-recognition protein in the presence of laminarin, a soluble glucan, stimulated activation of pr

18 Moreover, our data revealed that laminarin accounted for up to 50% of organic carbon in s

19 e beta-1,3-glucan curdlan but not on soluble laminarin; additional deletion of the CBM6 also did not

20 ation of prophenoloxidase in plasma, whereas laminarin alone did not.

21 We measured laminarin along transects in the Arctic, Atlantic, and P

22 Vaccine containing laminarin also affected distribution of IgG subclasses,

23 An increased level of beta-1,6 branching in laminarin also results in destabilization of the macro c

24 an receptor antagonists laminariheptaose and laminarin also substantially reduce the ability of the P

25 cated that all of the preparations contained laminarin although their molecular mass varied considera

26 Administration of short chain beta-glucan laminarin, an antagonist of Dectin-1, suppresses the dev

27 Blocking experiments with laminarin and mannan supported the conclusion that diffe

28 f two fluorescently labeled polysaccharides, laminarin and xylan, in environmental samples.

29 ared to other beta-glucans such as lentinan, laminarin, and curdlan.

30 nistic studies using the Dectin-1 inhibitor, laminarin, and Dectin-1-/- mice revealed that Galectin-3

31 C. neoformans-selected B-1 B cells secreted laminarin- and C. neoformans-binding IgM.

32 d B-1,4 glycosidic bonds in glucans, such as laminarin, barley B-glucan, and cello-oligosaccharides.

33 In this study, laminarin (beta-1,3-glucan) but not sialic acid, mannan

34 Laminarin (beta-glucan) or galactose-BSA were not inhibi

35 Our data demonstrate that laminarin can be either a Dectin-1 antagonist or agonist

36 This enzyme did not hydrolyze laminarin, carboxymethylcellulose, pustulan, or xylan.

37 ctly adapted to the U-shaped conformation of laminarin chains in solution and thus explains the predo

38 ucan), 1 to 10 microm beta-glucan particles, laminarin-coated latex beads, 1 microm latex beads, 50 t

39 ence interval [CI], 3.0 to 11 microM), while laminarin competed for 69% +/- 6% of binding sites, with

40 us derived from this study for the N-betaGRP-laminarin complex in solution differs from the one in wh

41 (AUC) studies of formation of the N-betaGRP-laminarin complex show that ligand binding induces self-

42 Spatially and temporally variable laminarin concentrations in the sunlit ocean are driven

43 Two of the laminarins contained substantial quantities of very low

44 (GXM)- and naturally occurring beta-glucans (laminarin, curdlan)-binding antibodies were measured in

45 nal deletion of the CBM6 also did not affect laminarin degradation but further decreased curdlan hydr

46 FRET spectra of the triple-helix glucan, laminarin, doubly labeled with 1-aminopyrene as donor pr

47 The soluble complex with laminarin formed in the plasma also stimulated pro-PO ac

48 ological role and biogeochemical function of laminarin in oceanic carbon export and energy flow to hi

49 Conjugation of ovalbumin to laminarin increased its immunogenicity while at the same

50 d to directly bind to live mycobacteria in a laminarin-inhibitable manner indicating the presence of

51 Soluble mannan, but not soluble laminarin, inhibited cytokine production following stimu

52 Ebg1 can hydrolyze beta-1,3-glucan and laminarin into glucose, thus suppressing beta-1,3-glucan

53 es that specifically cleave the algal glycan laminarin into readily analyzable fragments.

54 Laminarin is a (1-->3, 1-->6)-beta-glucan that is widely

55 antagonist, however, there are reports that laminarin is also a Dectin-1 agonist.

56 ucuronoxylomannan (GXM) capsule-specific and laminarin (Lam)-binding IgM and IgG, and percentages of

57 Laminarin (LAM-OH) is a highly abundant, nontoxic, degra

58 te in part to the stability of the N-betaGRP-laminarin macro complex and that a decreased stability i

59 enan, porphyran), brown (alginate, fucoidan, laminarin, mannitol), and green (ulvan) seaweeds, emphas

60 These laminarins may be useful in elucidating the structure an

61 y low m.w. compounds, some of which were not laminarin. moieties could be significantly reduced by ex

62 ure, likely containing six protein and three laminarin molecules (~102 kDa).

63 narin suggests an annual production of algal laminarin of 12 +/- 8 gigatons: that is, approximately t

64 ype, while the defence program after chitin, laminarin, oligogalacturonide or flg22 treatment and the

65 proposed to bind to a triple-helical form of laminarin on the basis of an X-ray crystallographic stru

66 (iii) Absorption of IgM with laminarin or curdlan (branched and linear 1-3-beta-d-glu

67 Treatment of SpDC with laminarin or glucan phosphate, two molecules known to bl

68 ited by glycogen, dextran, mannan, pustulan, laminarin, or a low molecular weight beta-(1-3)-glucan,

69 and in cells exposed to lipopolysaccharide, laminarin, or viral immune challenge.

70 , allergenicity, and therapeutic efficacy of laminarin-ovalbumin neoglycoconjugates (LamOVA).

71 cal properties, purity, and structure of the laminarin preparation employed.

72 g, and biological activity of five different laminarin preparations from three different commercial s

73 All of the laminarin preparations were bound by recombinant human D

74 igands for the receptor in the bacterium and laminarin pretreatment resulted in reduced association o

75 Strain 83-1 furthermore hydrolysed laminarin, pullulan and xylan, and corresponding polysac

76 ed glucosyl homopolysaccharide (pustulan and laminarin, respectively), suggesting that SP-D recognize

77 Additionally, pustulan but not laminarin strongly inhibited SP-D binding to A. fumigatu

78 antibody as well as the soluble beta-glucan, laminarin, suggesting the importance of Dectin-1 in the

79 observed correlation between chlorophyll and laminarin suggests an annual production of algal laminar

80 We were able to identify a laminarin that is a Dectin-1 agonist and a laminarin tha

81 a laminarin that is a Dectin-1 agonist and a laminarin that is Dectin-1 antagonist, both of which are

82 m organisms that are in contact with genuine laminarin, the storage polysaccharide of brown algae.

83 Conjugation of laminarin to ovalbumin reduced its IgE binding capacity

84 Laminarin treatment also inhibited mycobacterial-induced

85 The remaining laminarin was a Dectin-1 antagonist, but when the low m.

86 etyl-D-glucosamine, mannose-6-phosphate, and laminarin were found to inhibit adhesion of T84 cells to

87 In both human and mouse cells, two laminarins were Dectin-1 antagonists and two were Dectin

88 , BhCBM56, bound the soluble beta-1,3-glucan laminarin with a dissociation constant (Kd ) of approxim

89 These data revealed a median of 26 +/- 17% laminarin within the particulate organic carbon pool.