ライフサイエンスコーパス: large dose

1 talyst doses are not more efficient than one large dose.

2 rug, can damage various organs when taken in large doses.

3 imited dosing options, which often result in large dose adjustments in response to toxicity, the real

4 ltiple immunosuppressive agents are given in large doses after kidney transplantation in an attempt t

5 have limited efficiency, require high power, large doses, and long irradiation times.

6 these therapeutic proteins requires multiple large doses, and their efficacy is highly debated among

7 Improgan produced large, dose- and time-related reductions in nociceptive

8 However, large doses are associated with adverse effects such as

9 nds, however, is limited by requirements for large doses because of their rapid metabolism and their

10 Large-dose carnitine treatment is effective in systemic

11 l provides a means of delivery of localized, large dose density of beta radiation to the object but a

12 There was a large dose-dependent increase in the occurrence of psych

13 Extracellular NH(4)Cl evoked large dose-dependent inward currents in HEK-293 cells ex

14 e platform to manage, analyze, and visualize large, dose-dependent cell proliferation datasets.

15 timates than do standard dosing methods, and large dosing errors are possible in patients with aberra

16 vivo biodistribution and PET for comparably large doses, for example, 6 nmol (0.65 mg/kg) (68)Ga-aqu

17 There was large dose heterogeneity at both the intimal and adventi

18 Although there may be large dose heterogeneity, gamma irradiation (using a fix

19 ccounts for the anti-inflammatory effects of large-dose i.v. Ig (IVIg) in autoimmunity.

20 by dioxygen (O(2)), necessitating unfeasibly large doses in a therapeutic setting.

21 approach, together with the introduction of large-dose iron preparations, raises the future specter

22 Pyridoxine given in large doses is thought to destroy selectively the large-

23 doses of that antigen until they tolerate a large dose, is an effective, but risky, way to induce te

24 equate to describe the biological effects of large dose levels from homogeneous sources.

25 We investigated the effect that single-large-dose maternal/neonatal vitamin A supplementation h

26 translation to the clinic is impeded by the large doses needed.

27 them to a pulse perturbation consisting of a large dose of broad-spectrum antibiotics before transpla

28 on of the urinary tract but at the cost of a large dose of contrast medium (100-150 ml), high radiati

29 Although it was shown recently that one large dose of ethanol caused hypoxia in rat liver in viv

30 Acute treatment with one large dose of ethanol, which mimics binge drinking, caus

31 A large dose of exogenous mtDNA reversed protection by BAM

32 B7-encoding virus survived challenge with a large dose of HSV-2, whereas most 5BlacZ-immunized mice

33 d the biodistribution of (124)I-huA33 when a large dose of human intravenous IgG (IVIG) was administe

34 antly greater in tumors preirradiated with a large dose of ionizing radiation.

35 A single large dose of L-triiodothyronine given to hypothyroid ra

36 otherwise fatal, demonstrated that a single large dose of micafungin could clear disseminated candid

37 delivery device (A2D2) that can administer a large dose of naloxone upon detection of overdose-induce

38 A large dose of phenylephrine (3000 nmol) completely block

39 same regimen with the addition of a single, large dose of posttransplant MTX on day +3 (50-400 mg/m2

40 centration remains relatively static after a large dose of preformed vitamin A and therefore is not a

41 it toward the public interest will require a large dose of public participation.

42 future chemoprevention studies to provide a large dose of tea polyphenols without the side effects o

43 al hematoma, an intracerebral injection of a large dose of thrombin or cerebral ischemia.

44 r significantly between mice infected with a large dose of virus and those infected with a small dose

45 itis in mice infected intracerebrally with a large dose of virus.

46 e, after absorption but before storage) of a large dose of vitamin A or to the short- and long-term e

47 Some animals (N=4) received large doses of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyri

48 ethod was applied to the question of whether large doses of 2-nitropropane produce oxidized proteins.

49 focal stereotactic radiosurgery with single large doses of 40-100 Gy to 5-7.5 mm fields in the left

50 cality and reliability for the production of large doses of [(18)F]7.

51 the liver to uptake, catabolize, and excrete large doses of Abeta, several orders of magnitude above

52 s associated with systemic administration of large doses of adenoviral vectors.

53 In a model in which short-term and large doses of ammonia were infused, the decrease in bra

54 extended ICU care (> or =7 days) who receive large doses of analgesic and sedative medications are at

55 Self-administration of large doses of androgenic-anabolic steroids (AAS) in a s

56 ective treatment requires that patients take large doses of antibacterial drug combinations for at le

57 econd, the initial proliferative response to large doses of antigen did not require costimulation: in

58 First, large doses of antigen inhibited the early (day 3) proli

59 The response to large doses of antigen was quite different in two respec

60 rum-sensing systems that were operative when large doses of bacteria were applied to cultured lung ep

61 es showed that treatment of female rats with large doses of Cetrorelix, an antagonist of luteinizing

62 acterized by an opposite effect in small and large doses of chemical exposure, often resulting in see

63 Large doses of chemical pesticides are required to achie

64 The patient responded to large doses of desmopressin (dDAVP) which decreased urin

65 Because large doses of dietary alphaT displace gammaT in plasma

66 requirement for toxic immunosuppression and large doses of donor bone marrow (BM) cells.

67 .34 ml/min), GFR values were reduced only by large doses of drug monotherapy, namely RAPA (3.2 mg/kg

68 tinal transplant recipient who required very large doses of either tacrolimus or cyclosporine emulsio

69 The i.n. inoculation of BALB/c mice with large doses of ETEC strains H10407 and B7A caused illnes

70 m drinking water with ethanol, acute, single large doses of ethanol gavage, multiple alcohol gavages

71 However, large doses of exogenous insulin are associated with hyp

72 s undergoing immune tolerance induction with large doses of factor VIII to eradicate inhibitors.

73 Large doses of gentamicin cause nephrotoxicity and ototo

74 Even when large doses of heparin are administered during cardiopul

75 lenges, yet most experiments focus on single large doses of infectious material.

76 type 2 diabetes are often obese and require large doses of insulin to achieve glycemic control.

77 Large doses of iron are most often prescribed and are as

78 dividuals immunized intravenously with three large doses of irradiated sporozoites, and malaria-naive

79 triacylglycerol absorption, especially with large doses of lipid, is transport of prechylomicrons fr

80 Peripheral administration of large doses of lithium chloride (LiCl) to rats causes a

81 ded an efficient vehicle for the delivery of large doses of Mn2+ ions which exhibited very high in vi

82 ely to severely parkinsonian after receiving large doses of MPTP over 9-30 d and remained symptomatic

83 came moderately parkinsonian after receiving large doses of MPTP over short periods of time and were

84 rkinsonian with short term administration of large doses of MPTP.

85 If large doses of MTB were injected in saline, caseating gr

86 etagamma signaling could reduce the need for large doses of opioid analgesics to treat pain by produc

87 Treatment with large doses of oral vitamin K1, often over months to yea

88 r spectrum of anti-NP antibody isotypes than large doses of OVA in alum adjuvant.

89 d, the vaccinees and controls are exposed to large doses of pathogenic SIV.

90 velop significant hypophosphatemia requiring large doses of phosphate replacement to maintain metabol

91 the versatility of this platform to deliver large doses of physico-chemically diverse agents.

92 lets stored for 48 hours or less, and giving large doses of platelets while ultraviolet B (UV-B) or g

93 The effects of large doses of preformed vitamin A, such as those provid

94 neutralizing anti-IL-12 antibodies survived large doses of primary and secondary LVS infection but n

95 ice) of heterodimeric IL-12 readily survived large doses of primary sublethal LVS infection as well a

96 The prolonged use of large doses of propofol to treat refractory status epile

97 ase in absolute risk for those receiving the large doses of radiation associated with radiotherapy ma

98 sed rate of thrombosis in patients receiving large doses of recombinant erythropoietin.

99 Large doses of rifampicin and fluoroquinolones might imp

100 This suggests a model in which large doses of risk variants cause illness, but mild to

101 4-induced antinociception was not reduced by large doses of systemically-administered antagonists of

102 Mice were resistant to large doses of the same virus inoculated subcutaneously,

103 Inoculation of rabbits with large doses of the truncated intimin mutant (RDEC-1Delta

104 justification for the administration of the large doses of this expensive medication.

105 o numerous environmental stresses, including large doses of ultraviolet (UV) radiation and extreme te

106 ion was potently inhibited by coinjection of large doses of unpurified sporozoites and by uninfected

107 on of VACV following systemic infection with large doses of virus, it is wholly disposable in both co

108 A toxicity was described in patients taking large doses of vitamin A and in patients with type I hyp

109 placebo-controlled trial to examine whether large doses of vitamin A given to Tanzanian children who

110 Large doses of vitamin A had no protective effect on the

111 Large doses of vitamin B6 may reduce the risk of kidney

112 Oral delivery of a large dose or prolonged feeding of protein Ags induce sy

113 Antipyretic analgesics, taken in large doses over a prolonged period, cause a specific fo

114 weet spices descriptors were obtained when a large dose rate of chips was employed.

115 cribed by physicians in doses lower than the large doses that have been shown to reduce morbidity and

116 previous studies which have used relatively large doses, the doses of heroin used in this study have

117 mAbs can be safely administered as a single large dose to mice with typical susceptibility to anaphy

118 highly infectious among humans but requires large doses to colonize rodents, unlike a closely relate

119 ed with exogenous insulin but often requires large doses to overcome the insulin resistance.

120 World Health Organization recommends single-large-dose vitamin A supplementation for postpartum wome

121 Multiple-large-dose vitamin A supplementation of HIV-positive chi

122 the endomorphins attenuated the HCVR only in large doses, well beyond the analgesic threshold, and di