ライフサイエンスコーパス: large-scale study

1 this practice has not been evaluated in any large scale study.

2 for the data set, consistent with a previous large-scale study.

3 ndicator and should be further explored in a large-scale study.

4 edure which makes this approach suitable for large scale studies.

5 to scale up the technique and to adapt it to large scale studies.

6 icient technique, thus it is able to fulfill large scale studies.

7 a novel targeted therapy after validation in large-scale studies.

8 ods and highlight the application of BiFC in large-scale studies.

9 mitis were low and similar to those in other large-scale studies.

10 further validated with PET-autopsy data from large-scale studies.

11 tigen selection, they are not applicable for large-scale studies.

12 and endoscopic tools requiring validation in large-scale studies.

13 ss the various challenges these data pose to large-scale studies.

14 methods are required to efficiently scale to large-scale studies.

15 lected on filter paper and can be applied to large-scale studies.

16 taken before analysing accelerometer data in large-scale studies.

17 population stratification in these types of large-scale studies.

18 g, which is a major source of variability in large-scale studies.

19 nt from the literature, mostly for a lack of large-scale studies.

20 sure time, but this has not been verified in large-scale studies.

21 ethods are often prohibitively expensive for large-scale studies.

22 multiplex serology to establish an assay for large-scale studies.

23 sible screening test, but there have been no large-scale studies.

24 r improving the quality of results, enabling large-scale studies.

25 nd Central Asia) have rarely been sampled in large-scale studies.

26 tool to detect likely technical artifacts in large-scale studies.

27 hese populations has yet to be determined in large-scale studies.

28 icant improvements over cartridge arrays for large-scale studies.

29 nd relate it to previous non-tissue-specific large-scale studies.

30 ystem are obstacles to its widespread use in large-scale studies.

31 alid data within the resource constraints of large-scale studies.

32 cadian rhythm (CR) using multiple metrics in large-scale studies.

33 enhancing the interpretation of results for large-scale studies.

34 ion to make bottom-up proteomics amenable to large-scale studies.

35 rtical characteristics related to ADHD using large-scale studies.

36 lity to cryopreservation damage have limited large-scale studies.

37 results and are particularly important with large-scale studies.

38 rent reference haplotypes are inadequate for large-scale studies.

39 cs and personalized medicine by facilitating large-scale studies.

40 cly available metagenomic samples from eight large-scale studies.

41 g region using models compiled from multiple large-scale studies.

42 on to the European Union proposals through a large-scale study (2.7 million birds) with the unprecede

43 s in online cognitive assessments facilitate large-scale studies across diverse populations, offering

44 Large-scale studies aimed at a molecular understanding o

45 Future large-scale studies aiming to understand the mechanisms

46 s thus open up the possibility of conducting large-scale studies analyzing thousands of samples simul

47 The technique is well suited for large scale studies and for analysis of clinical samples

48 blood spot and in principle is suitable for large scale studies and newborn screening.

49 epetition and validation of these methods in large-scale studies and across different research groups

50 Recent large-scale studies and converging findings are beginnin

51 linked to chronic kidney disease (CKD), but large-scale studies and mechanistic insights are limited

52 generalizable approach that is suitable for large-scale studies and will enable the field to obtain

53 n of the types of prenylation in proteins in large-scale studies and will improve significantly our k

54 increasingly available from both small- and large-scale studies, and can be viewed as a network.

55 ly been noted that errors are frequent among large-scale studies, and that error frequency depends on

56 ight provide a simple, cheap alternative but large-scale studies are again needed.

57 However, large-scale studies are currently difficult to set up be

58 Further large-scale studies are needed to confirm these findings

59 Additional multicenter, large-scale studies are needed to develop more complete

60 Large-scale studies are needed to evaluate the potential

61 Large-scale studies are needed to evaluate whether exces

62 Large-scale studies are needed to identify the extent of

63 Large-scale studies are needed to investigate the effect

64 Further large-scale studies are needed to understand better the

65 Large-scale studies are required to better characterise

66 Although large-scale studies are required to change current follo

67 Additional large-scale studies are warranted for these complex phen

68 And further large-scale studies are warranted to assess its prognost

69 Further large-scale studies are warranted to confirm the potenti

70 Large-scale studies are warranted to evaluate whether di

71 Large-scale studies are warranted to identify individual

72 Robust, large-scaled studies are required to better quantify the

73 e occurrence of which, based on contemporary large-scale studies, are unlikely to have important clin

74 of early nutrition has been defined in most large-scale studies as beginning within 48 h of intubati

75 This large-scale study assessed cognitive and behavioral func

76 we address this gap by performing the first large-scale study assessing both ontogenetic and adult c

77 This large-scale study based on nationwide data from Sweden a

78 We provide empirical evidence supported by a large-scale study, based on three deep neural network ar

79 We performed a large-scale study by creating breast cancer metastasis n

80 Evidence comes from a large-scale study conducted with 10 measures of independ

81 cessing of N-linked glycans would facilitate large-scale studies correlating the glycome with disease

82 tural surface waters is a common phenomenon, large-scale studies dealing with the responsible drivers

83 In this large-scale study, delaying revascularization with PCI>2

84 al.'s bottom-up approach, we conducted four large-scale studies designed to assess people's concepti

85 nterest in incorporating this technique into large-scale studies, e.g., clinical and molecular phenot

86 urrent research efforts, with an emphasis on large-scale studies, emerging technologies, and challeng

87 ial to create substantial false positives in large-scale studies even when a small fraction of marker

88 ci associated with lipid traits, however, no large-scale studies exist for Hispanics and other minori

89 However, not a single large-scaled study exists to investigate the optimal pos

90 This large-scale study explored a standardized methodology fo

91 We present a large-scale study exploring factors defining urinary mic

92 ficits in autism spectrum disorder (ASD), no large-scale study has been conducted.

93 This large-scale study has enabled in-depth analyses on how p

94 However, no large-scale study has examined psychiatric disorders aft

95 To date, no large-scale study has examined the comorbidity and conti

96 However, no large-scale study has yet estimated the number of expect

97 No large scale studies have evaluated so far what symptom d

98 Moreover, few large-scale studies have assessed asymmetries of subcort

99 Several large-scale studies have attempted to identify mRNAs bou

100 ies with morphea subtype or severity, but no large-scale studies have been conducted.

101 cts of TIPS have been confirmed, however, no large-scale studies have been focused on technical analy

102 the most promising susceptibility genes, but large-scale studies have been lacking.

103 Large-scale studies have clarified a number of long-susp

104 Few large-scale studies have considered both food sources an

105 Recent large-scale studies have created genome-scale catalogs o

106 actor for cardio-metabolic diseases, but few large-scale studies have examined the clinical profile o

107 To the authors' knowledge, no large-scale studies have examined the effects of languag

108 So far, no large-scale studies have focused on defining a comprehen

109 such as measles-mumps-rubella immunization, large-scale studies have not supported such links.

110 far more prevalent and severe than previous large-scale studies have portrayed.

111 een shown to predict warfarin dosing, but no large-scale studies have prospectively evaluated the cli

112 Few large-scale studies have quantified and characterized th

113 Large-scale studies have revealed how editing is regulat

114 through sites in open reading frames (ORFs), large-scale studies have shown such targeting to be gene

115 Recently, a large-scale study highlighted some of the benefits of ca

116 Small invertebrates are ideal for these large-scale studies; however, patch-clamp electrophysiol

117 X-PCR fingerprinting is more appropriate for large-scale studies (i.e., global epidemiology).

118 Recent large-scale studies illustrate the importance of electro

119 This large-scale study implicates an aetiological role of the

120 Large-scale studies in clinical populations are needed t

121 Acamprosate (grade A, from large-scale studies in Europe) reduces drinking frequenc

122 These observations may help guide future large-scale studies in examining host SNPs for their cli

123 fy the underlying disease-causing genes, but large-scale studies in human cellular models have previo

124 risk factors for cardiovascular disease from large-scale studies in humans.

125 variability of the results while conducting large-scale studies in investigative pathology and oncol

126 of the UbiFast method makes it suitable for large-scale studies in primary tissue samples.

127 eneric, low-cost sofosbuvir and daclatasvir, large-scale studies in resource-limited countries are no

128 ausal variant that is undetected by existing large-scale studies in resting cells.

129 s is increasingly being recognized, previous large-scale studies in schizophrenia (SZ) have primarily

130 d by genome-wide association studies (GWAS), large-scale studies in which the entire genome is covere

131 This is the first large-scale study in diffuse large B-cell lymphoma to us

132 A large-scale study in maize generated 40,299 HMPR sequenc

133 Here, we present a large-scale study in which we investigated duplicate ret

134 or family-based association tests (FBATs) in large-scale studies, including genome-wide association s

135 Recent large-scale studies, including those of Behrends et al.

136 equires extensive manual review, which makes large-scale studies inconvenient.

137 This large-scale study indicates structural thalamic abnormal

138 To facilitate large-scale studies into early-stage neurodegeneration,

139 However, large-scale studies investigating an association between

140 datasets is a complex but essential task for large-scale studies investigating protein-protein intera

141 However, until recently, large-scale studies investigating the diversity of speci

142 To date, there have been few large-scale studies investigating the postoperative outc

143 d in medicine, particularly surgery, with no large-scale studies investigating their training experie

144 This large-scale study investigating key aspects of the PANDA

145 However, large-scale studies involving classical type I and type

146 g data, the qMSAT is especially valuable for large-scale studies involving rare variants, as it can p

147 In a large-scale study involving 55 species and 550 populatio

148 s for children with acute gastroenteritis, a large-scale study is needed in future.

149 A large-scale study is needed to confirm these results.

150 A large-scale study is needed to investigate the outcome o

151 A large-scale study is required to substantiate findings a

152 The findings in this large-scale study may clarify previous inconsistencies a

153 The main purpose of this large-scale study (n = 185) covering a wide age range of

154 labor-intensive methodology have limited the large-scale studies necessary for statistical validation

155 ocols dedicated to CAAs can give rise to the large-scale studies needed to define the prognosis and o

156 Especially in large-scale studies, normalization is crucial for drawin

157 ieved to have adverse health effects; recent large scale studies now confirm relationships between ch

158 A large-scale study now reveals that inhibition of recepto

159 throughput experimental data (e.g. data from large scale studies of gene expression and polymorphism

160 Advances in proteomics and large scale studies of potential mitochondrial proteins

161 This first, large scale study of PR gene regulation has important im

162 We conducted a large scale study of the distribution of protein domains

163 However, there are no large-scale studies of actual PSA screening practices in

164 However, large-scale studies of AF risk among patients with LQTS

165 are being deposited into this database from large-scale studies of Arabidopsis thaliana and soybean.

166 We discuss the feasibility of large-scale studies of asymptomatic at-risk subjects tha

167 Here, we combined tools used in large-scale studies of biodiversity (remote sensing and

168 nical variability, which allows its usage in large-scale studies of chromatin from normal or diseased

169 Yet recent large-scale studies of community regulation in marine ec

170 Few large-scale studies of epilepsy have been done in sub-Sa

171 Recent large-scale studies of evolutionary changes in gene expr

172 As large-scale studies of gene expression with multiple sou

173 nd validated human transcribed sequences for large-scale studies of gene expression.

174 Overall, we show that large-scale studies of gene function in model organisms

175 ophila melanogaster is a promising model for large-scale studies of genes involved in the pathogenesi

176 the mSFP identified will greatly facilitate large-scale studies of genome variation in the P. falcip

177 ng to generate new trisomic mouse models and large-scale studies of genotype-phenotype relationships

178 We review recent large-scale studies of habitat adaptation, with emphasis

179 By analysing data from large-scale studies of households, we estimate that pneu

180 autism, and it is extensively used in other large-scale studies of human diseases.

181 d by selected examples, our approach enables large-scale studies of human neurons for questions such

182 ying gene-environment interactions (GxEs) in large-scale studies of human populations.

183 Recent large-scale studies of individuals within a population h

184 Whole HIV-1 genome sequences are pivotal for large-scale studies of inter- and intrahost evolution, i

185 Large-scale studies of linkage disequilibrium (LD) have

186 To carry out large-scale studies of LOH and MI in cancer progression,

187 near-full-length sequences for three recent large-scale studies of microbial communities in the mous

188 the field of animal migration [1] that only large-scale studies of migration patterns across a speci

189 Large-scale studies of morbidity and mortality in unsele

190 Large-scale studies of mRNA expression have displayed th

191 No large-scale studies of mutation identification and scree

192 Supporting this view, large-scale studies of national African demographic surv

193 olving tens to hundreds of samples, enabling large-scale studies of natural and engineered cell popul

194 technology should enable statistically rich, large-scale studies of neural development, sexual dimorp

195 nd at home and enable researchers to conduct large-scale studies of neurological and musculoskeletal

196 should be carefully reviewed before further large-scale studies of patients with sepsis are conducte

197 analyses of mRNA and protein expression, but large-scale studies of protein dynamics and turnover hav

198 s--and actual fluorescent imagesfrom ongoing large-scale studies of protein localization in S.cerevis

199 Large-scale studies of relatively homogeneous samples, i

200 d preterm delivery found in this study, more large-scale studies of temperature and preterm delivery

201 filter paper may increase the feasibility of large-scale studies of the determinants of insulin sensi

202 Large-scale studies of the dynamic phosphorylation state

203 However, large-scale studies of the effects on cardiovascular out

204 Moreover, these findings should motivate large-scale studies of the longitudinal expression in pa

205 e quantification tools are a prerequisite to large-scale studies of the molecular mechanisms of subce

206 ed genes has long fascinated biologists, but large-scale studies of their expression dynamics and mol

207 asurement of thousands of proteins, enabling large-scale studies of various biological systems.

208 They have also enabled large-scale studies of vertebrate genome evolution, as w

209 ster model is a promising minihost model for large-scale studies of virulence mechanisms and antifung

210 study presents longitudinal evidence from a large-scale study of >2,000 children ages 6-12 living in

211 To perform the first large-scale study of automatic adipocyte phenotyping usi

212 comparison participants recruited through a large-scale study of brain imaging and genetics.

213 A large-scale study of causative allergen components of sh

214 In the first large-scale study of deadwood in Central Africa, we quan

215 smission between related individuals, but no large-scale study of families that would reflect the typ

216 A large-scale study of fungal genomics provides new insigh

217 We have conducted a large-scale study of gene expression in the C4 monocot s

218 asurement of pesticide exposure markers in a large-scale study of human urine has been proposed and a

219 Finally, we apply our approach to a large-scale study of immune system variation.

220 In this large-scale study of known eukaryotic DNA and RNA viruse

221 cale up makes QuMFRA a valuable tool for the large-scale study of macromolecular interaction.

222 A large-scale study of methane emissions from well pads wa

223 We evaluated this hypothesis with a large-scale study of mitochondrial DNA (mtDNA) and Y-chr

224 To our knowledge, this is the first large-scale study of mtDNA variation in single malignant

225 otein families and apply DCA to a systematic large-scale study of nearly 2,000 Pfam protein families

226 viously reported enzyme knockout study and a large-scale study of plasma samples.

227 We performed a large-scale study of protein homooligomers in terms of t

228 (XL-MS) has emerged as a useful tool for the large-scale study of protein structures and interactions

229 scribe the formation of a group dedicated to large-scale study of PTSD genetics: the PGC-PTSD.

230 Here, we report a large-scale study of resting state functional connectivi

231 In a large-scale study of socioeconomically homogeneous men t

232 Here, we report on the first large-scale study of the accuracy and reliability of lat

233 Here, we present findings from a large-scale study of US SFES, who are widespread and inc

234 We have undertaken a large-scale study of various tissues from normal control

235 We conducted a large scale study on the sxt gene and toxin distribution

236 methodology could potentially be applied in large-scale studies on fruit quality, authenticity/varie

237 We review and integrate the recent in-depth large-scale studies on human immune diversity and its po

238 cellular trafficking, and this has motivated large-scale studies on lipid pathways.

239 However, there is little evidence from large-scale studies on the prevalence and management of

240 differentially expressed genes in subsequent large-scale studies on the same platform, but in which t

241 Here, we present a large-scale study on a non-redundant set of about 20,000

242 Here, we describe a large-scale study on assigning function to unknown membe

243 Through a large-scale study on mammalian miRNA turnover, we report

244 This paper describes a large-scale study on the nature and the energetics of th

245 In large scale studies, once miRNAs of interest have been i

246 that are either too labor intensive to allow large-scale studies or not sufficiently quantitative to

247 miquantitative profiling data from different large scale studies over the time course of years, the m

248 This large-scale study overcomes the challenges associated wi

249 This large-scale study potentially resolves the complex relat

250 A large-scale study provides a causal test for a cornersto

251 This large-scale study provides important insights into the m

252 This large-scale study provides insight into the utility of t

253 This large-scale study provides novel insights into cognitive

254 In large-scale studies, RFLP typing has practical processin

255 Further large-scale studies should be done to confirm our findin

256 Ongoing large-scale studies should help clarify such outstanding

257 A large-scale study shows that high fruit and vegetable co

258 and epilepsy), and (3) additional data from large-scale studies, smaller cohorts, and case reports f

259 For large-scale studies, submitting short phrases encased in

260 This large-scale study substantially enhances our understandi

261 ting rare variant associations identified in large-scale studies, such as exome re-sequencing project

262 will enable the feasibility of conducting a large-scale study, such as the Human Epigenome Project.

263 Our data converge with prior large-scale studies suggesting small or limited associat

264 n, as well as the scarcity of comprehensive, large-scale studies that assess both the genomic landsca

265 iation in defence, highlighting the need for large-scale studies that can differentiate competing env

266 Large-scale studies that have been recently conducted an

267 ese phenotypes, there is currently a lack of large-scale studies that have specifically examined the

268 re is no definitive evidence from published, large-scale studies that one approach is superior to the

269 We present a large-scale study that compares the sequences and best e

270 A comprehensive large-scale study that examines systemic proteomic expre

271 We used available proteomic data from large scale studies to narrow down potential phospho-tyr

272 Large-scale studies to better address post-explantation

273 However, large-scale studies to detect long-term trends of C and

274 amined over 3,800 unique MRI scans from nine large-scale studies to estimate the morphometricity of a

275 There is a need for large-scale studies to generate robust data for testing

276 ific for the functional gene is critical for large-scale studies to identify the role of the PRNP gen

277 ease has been poorly explored, and this is a large-scale study to ascertain the association between d

278 Here, we report a large-scale study to assess SARS-CoV-2 infection in 919

279 Our results warrant a large-scale study to examine the effect of the A133S pol

280 A large-scale study to identify functional variants in G-p

281 Here we have undertaken a large-scale study to investigate the existence of duplic

282 At this time, these large-scale studies typically utilize a simple kinetic m

283 Using this framework, we did a systematic, large-scale study under a new-user cohort design to esti

284 l and public policy recommendations, but few large-scale studies use 24-h urine collections.

285 However, large-scale studies using sensitive measurements of HIV

286 In large-scale studies, virtually every chip contains some

287 In the context of this large-scale study we obtained a false positive rate of a

288 To meet the challenges in making feasible large-scale studies, we present the REgional heritabilit

289 After our exploratory study and a large-scale study, we conducted this gateway trial in or

290 nd to examine the reported interactions in a large-scale study.We systematically reviewed studies rep

291 Despite several large-scale studies which have characterized the acetylo

292 Applying this strategy to large-scale studies will greatly reduce the time and cos

293 Although a large-scale study will be necessary to confirm clinical

294 However, further large scale studies with longer follow up period is nece

295 al environment in which to analyze small- to large-scale studies with data from the latest genotyping

296 Future large-scale studies with functional characterization of

297 No large-scale studies with long-term oncological outcomes

298 t that the concept of defense is useful, but large-scale studies with representative cohorts are lack

299 However, the power gain is small (1) for large-scale studies with thousands of individuals, becau

300 Further large-scale studies, with better methods of assessing mi