ライフサイエンスコーパス: last

1 reporter becomes unstable when fused to the last 10 amino acids of SpxA2 but remained stable when fu

2 Funding to DoS has doubled in the last 10 years ($22,983,500-2008 to $49,446,076-2018).

3 Consecutive cases of ICRSs explanted in the last 10 years were reviewed.

4 itish populations diverged over at least the last 10,000 years (p = 0.0082), consistent with a signat

5 The last 10-15 years have seen major advances in thoracic im

6 n SWW forcing during the Holocene (i.e., the last ~11,700 y) have been documented, evidence of the oc

7 ects a rapid speciation-rate decrease in the last 12 million years.

8 covery and resilience were tested during the last 14 days by operating all reactors at low F:M and C:

9 st subclades dramatically increased over the last 15 million years (Myr) during cooling associated wi

10 For example, in the last 15 years, experiments have progressed from measurin

11 Over the last 15 years, research on canid cognition has revealed

12 d in 131 clinical reports published over the last 15 years.

13 ut was enhanced over 10-fold by deleting the last 19 amino acids of the cytoplasmic tail.

14 romised status have been remarkable over the last 2 decades, but sepsis continues to be a major cause

15 Over the last 2 decades, vascularized composite allotransplantati

16 During the last 2 years there has been a preponderance of data demo

17 ng event with extreme R(onset) The epizootic lasted ~2 mo, extending beyond the warming events throug

18 o determine an extinction process during the last 20 million years of the Late Cretaceous.

19 Over the last 20 years, evidence has accumulated that implicates

20 e has received increasing attention over the last 20 years.

21 iated gene therapy has been shown within the last 20 yr to correct the T cell immunodeficiency caused

22 nesis has increased substantially during the last 20 yr.

23 e proportion of patients with zero/near-zero last-24-hour OME and limiting prescriptions to a conserv

24 riptions to a conservative multiplier of the last-24-hour OME.

25 .12) were independently associated with zero last-24-hours OME (all P <= 0.040).

26 ntroduced framework to analyse data from the last 25 years on ecological stressor interactions, for e

27 linical trials and clinical practice in this last 30 years.

28 U.S. Food and Drug Administration during the last 30 years.

29 ean number of migraine days per month in the last 4 weeks of the double-blind treatment phase (weeks

30 emissions of 0.06-0.14 Tg CO(2-eq) over the last 40 years in Cockburn Sound.

31 Darussalam affected by seven fires over the last 40 years.

32 ropogenic atmospheric lead (Pb) spanning the last 4000 years, an effective indirect proxy for reliabl

33 8-219 months), and median imaging follow-up lasted 41 months (range, 0-189 months).

34 ed four weeks later, the epidemic could have lasted 49 days longer (95% CI: 31-68 days), causing 9,21

35 In the last decade, and especially in the last 5 years, there has been exponential growth in the n

36 ost studied two-dimensional materials in the last 5-10 years due to their extremely interesting layer

37 , with an overall increase of 30-fold in the last 50 years, mainly due to city population growth, mor

38 rones have been extensively examined for the last 50 years, most studies have focused on regulation o

39 ave undergone a species radiation during the last ~50,000 generations.

40 f regional fossil CO(2) emissions during the last 6 years, but forest growth saturation, land competi

41 roup that has been intensively bred over the last 60 years.

42 ttern has occurred numerous times during the last 70 years, including epidemics of dengue virus and W

43 for long-term human occupation, spanning the last ~80 thousand years, at the site of Dhaba in the Mid

44 Median clinical follow-up lasted 95 months (range, 8-219 months), and median imagi

45 Key questions are how protective and long-lasting a vaccine needs to be, and how to target it.

46 ly impact cortical development and have long-lasting adverse effects on neurodevelopmental outcome.

47 postnatal days 7, 9, and 11] results in long-lasting alterations in synaptic transmission and reduced

48 Since the publication of the last American Heart Association scientific statement on

49 Treatment of long-lasting and late diagnosed infection is difficult and re

50 These lasting and marked effects of M(1) receptor stimulation

51 r responses; moreover, such effects are long lasting and resistant to renewal and spontaneous recover

52 y drivers of health occur, for how long they last, and how they operate.

53 if less than 16 weeks have elapsed since the last anti-VEGF injection.

54 belonging to the same serogroup and by long-lasting antibodies from prior infections.

55 s lost to follow-up (LTFU, >90 days late for last appointment).

56 that moment in American history has, at long last, arrived.

57 coconut oil consumption with other fats that lasted at least 2 weeks.

58 ingestion of a spoiled food item leads to a lasting aversion towards cues reminiscent of the item.

59 e HAB toxin domoic acid (DomA) produces long-lasting behavioral deficits in rodent and primate models

60 respiratory disease in rhesus macaques that lasts between 8 and 16 days.

61 ics vary with the composite architecture and last beyond optical pulse temporal characteristics.

62 ic adaptations rather than the effect of the last bout of overnight fast.

63 ntry and waking from persistence may lead to lasting breakthroughs in malaria chemotherapy that can p

64 beta-band activity is characterized by short-lasting, burst-like events, rather than by steady modula

65 y western source region for these colonists, lasting c.

66 xposure, nadir CD4 count, CD4:CD8 ratio, and last CD4 level, calendar period of diagnosis was not ass

67 Epidemiological studies from the last century have drawn strong associations between pate

68 Nevertheless, until the end of the last century, few metal-isonitrile catalyzed processes w

69 ety of detergents have been developed in the last century, the challenge remains to identify guidelin

70 learning have been well established over the last century, we still lack a solid framework from which

71 democratic values and institutions over the last century.

72 tripling of atmospheric N deposition in the last century.

73 imate change-driven intensification over the last century.

74 dividuals are necessary but insufficient for lasting change.

75 modulate the release machinery, causing long-lasting changes in synaptic transmission that influence

76 The results reveal long-lasting changes in vlPAG/DR threat responding resulting

77 The last ciders were also more floral, buttery, acidic and b

78 in starting subsequent therapy and provided lasting clinical benefits versus placebo in all three an

79 eceptor CCR6, showed full rescue of the long-lasting colonization of the mutant, indicating a role fo

80 erial mutant without fully rescuing the long-lasting colonization of the mutant.

81 e root phase of the tree of life, before the last common ancestor of life (LUCA), exit tunnel evoluti

82 We show that bioluminescence evolved in the last common ancestor of mycenoid and the marasmioid clad

83 tion from the characters predicted for their last common ancestor.

84 Taken together, rTMS induced lasting connectivity and excitability changes from the s

85 ved species in particular, understanding the lasting consequences of early-life social environments r

86 ATEMENT Early-life stress (ELS) induces long-lasting consequences on stress responses and emotional r

87 Long-lasting, consolidated memories require not only positive

88 w spent much of his time and energy over the last decade after his retirement exploring the mysteriou

89 tion has been increasingly reported over the last decade and experience in managing these patients is

90 However, over the last decade B cells have been increasingly recognized as

91 have witnessed an increased interest in the last decade due to the large data availability and unpre

92 Scale-up of ART over the last decade has already contributed to substantial reduc

93 Work in the last decade has revealed that the Orai1 gating process i

94 Research in the last decade has uncovered many new paramyxoviruses, airb

95 The last decade has witnessed a burgeoning of new methods fo

96 Advances in the last decade have expanded our understanding and apprecia

97 Technological advancements made in the last decade offer unique opportunities to explore the ro

98 rhinal cortex, evidence accumulated over the last decade suggests that populations of "time cells" in

99 nd targets will be developed as we enter the last decade to meet the Sustainable Development Goals (S

100 In the last decade voltage modulation of ligand-induced GPCR ac

101 In the last decade, a large number of common variants underlyin

102 In the last decade, and especially in the last 5 years, there h

103 Over the last decade, genome-scale metabolic network reconstructi

104 In the last decade, interest in the use of beta gallium oxide (

105 eling has made significant advances over the last decade, its complex biological component is still o

106 abis use has increased dramatically over the last decade, resulting from mainstream cultural acceptan

107 Over the last decade, significant advancements have been made in

108 In the last decade, there has been tremendous progress in ident

109 ited States increased significantly over the last decade, whereas OOP expenses decreased.

110 generated an explosion of interest over the last decade.

111 heric processes and their changes during the last decade.

112 om positive to negative anomalies during the last decade.

113 rtery stenosis has proved difficult over the last decade.

114 mainly concentrating on advances during the last decade.

115 s, which have substantially increased in the last decade.

116 novel therapies have been identified in the last decade.

117 The last decades have seen an impressive development of iron

118 Studies over the last decades have shown that in solid tumors, IGFBP2 is

119 Over the last decades, great effort has gone into developing new

120 logical roles have also been obtained in the last decades, making MMPs attractive therapeutic targets

121 During the last decades, X-ray absorption spectroscopy (XAS) has be

122 alcohol use consistently increased over the last decades.

123 y studied by the scientific community in the last decades.

124 status and asthma have increased during the last decades.

125 e in young people, have increased during the last decades.

126 h the inability of ketamine to induce a long-lasting decrease in inhibitory neurotransmission.

127 These findings show GEE induces long-lasting deficits in cognitive function that may contribu

128 more-rapid sea-level rise compared with the last deglaciation.

129 emia and excitotoxicity in vitro and ex vivo Last, deletion of Bbeta2 rescued excessive stroke damage

130 ), generally alleviates pain and allows long-lasting dental function.

131 onization and engagement, rewards had a long-lasting desynchronizing effect.

132 In this review, we summarize the last developments regarding the potential role of hsTYR

133 reflect a complementary, and perhaps longer lasting, devolatilization history by solar heating.

134 Similarly, in Experiment 3, no long-lasting differences in these measures were observed when

135 Lasting DMSs mapped to distinct functional pathways and

136 Colitis was assessed one week after last dose of TNBS by histopathology and magnetic resonan

137 combination still produce amplified, longer-lasting effectiveness over single-approach interventions

138 Our results demonstrate lasting effects of PPS on the hippocampus and highlight

139 e development and through childhood may have lasting effects on respiratory health.Objectives: To inv

140 ittent hypercapnic hypoxia (IH) induces long-lasting elevations in sympathetic vasomotor outflow and

141 mediators of these effects, focusing on long-lasting epigenetic changes.

142 cent phases and the time elapsed between the last eruptions, we conclude that the waning/extinguishme

143 Last, feeding studies using male rats demonstrate that i

144 oup, the mean interval between the first and last ferumoxytol administration was 14 months +/- 8 (ran

145 with specific congenital anomalies over the last few decades and predict survival estimates up to 20

146 at have resulted from the discoveries of the last few decades.

147 le cases of hard selective sweeps within the last few thousand years on de novo mutations, mainly in

148 es of novel sonosensitizers developed in the last few years and outlines their specific designs and t

149 However, in the last few years, octacyanidometallate-based materials pro

150 Over the last few years, the field of protein structure predictio

151 Over the last few years, we have developed Epiviz as an integrati

152 scales suggest that the vesiculation process lasted few seconds.

153 fascinating applications have erupted in the last five years.

154 ose that turbulent coherent structures, long-lasting flow patterns which trap particles, may serve ma

155 39 patients still had a functional graft at last follow up and 9 (18.8%) pancreas grafts were lost d

156 followed through their clinical course with last follow up in 2019.

157 complications were reported under DOAC until last follow-up (14.1 +/- 13 mo).

158 iver was determined by ultrasound during the last follow-up (2011) at ages 34-49 years.

159 At last follow-up (mean, 20 months), of the entering 43 pat

160 ients (20%) by 12 months, and in 43 (34%) by last follow-up (median 63 months; interquartile range: 3

161 FMDRS-D) was evident at 6 months, 1 year and last follow-up (motor, P = 0.001, P = 0.004, and P = 0.0

162 sual acuity (VA) at initial presentation and last follow-up (up to 1 year) were the primary outcome m

163 patients required mechanical ventilation; at last follow-up, 16 were extubated.

164 At last follow-up, 36% ambulated with assistance (mean age:

165 At last follow-up, 41 patients (80%) were alive and disease

166 At last follow-up, eyes that returned to OR and control eye

167 ransplantation until development of obesity, last follow-up, or end of study.

168 ion, and all were considered disease free at last follow-up.

169 atment of an upper UTI needs to be broad and last for 10 days, a lower UTI only needs to be treated f

170 ents given donor stool reported effects that lasted for longer than 1 year compared with 5% of patien

171 on on the day of treatment, with attenuation lasting for up to 2 weeks after the larger MCAM dose and

172 Work over the last four decades has given us important insights into t

173 rom which they have been collected, dates of last frost have advanced much more rapidly than flowerin

174 the gadobenate dimeglumine washout since the last gadolinium exposure.

175 Long-lasting geographic isolation between glacial refugia cou

176 nd growth potential of Trichodesmium for the last glacial maximum (LGM), the present (2006-2015) and

177 hways of Southern Hemisphere dust during the Last Glacial Maximum (LGM).

178 ufacturers and a discontinuity marked by the Last Glacial Maximum (LGM).

179 During the Last Glacial Maximum in the Northern Hemisphere, expandi

180 al niche modeling to infer current and past (Last Glacial Maximum) environmental suitability across t

181 ealed population expansions, dated after the last glacial maximum.

182 riod encompassing the transition between the last glacial period and the current interglacial.

183 rd recolonization of northern Eurasia in the last glacial period.

184 of subfossil chironomid records spanning the last glacial-interglacial transition (~15,000-11,000 yea

185 most patients do not have disease remission lasting >18 months.

186 missions of a variety of B-cell malignancies lasting >= 3 years occurred after 51% of evaluable anti-

187 inite to a 12-month deferral since the donor last had sex with a man.

188 Patients' last histoplasmosis-associated healthcare visits occurre

189 In study 1, the change in EGP (baseline to last hour of EGP measurement) in subjects receiving dapa

190 Last, HRV(AV4) showed positive relationships (P = < 0.05

191 accines often fail to elicit potent and long-lasting immune responses.

192 can persist long-term, contributing to long-lasting immunity after infection or vaccination.

193 global public health issues with widespread, lasting impacts on children, families, and communities.

194 , marine heatwaves, can have severe and long-lasting impacts on marine ecosystems, fisheries and asso

195 Long-lasting insecticidal nets (LLINs) are believed to have h

196 Long-lasting insecticidal nets (LLINs) are the primary malari

197 re to pyrethroid based products such as long-lasting insecticidal nets (LLINs) has created mosquito p

198 ave been largely due to distribution of long-lasting insecticidal nets (LLINs)(5), with many SSA coun

199 of increased HIV knowledge and condom use at last intercourse among women.

200 eringia during high-magnitude warming of the last interglacial, followed by westward recolonization o

201 ylosyltransferase that acts on the second to last intermediate (MbA-XR(2)) in the pathway.

202 been correlated with expanded marine anoxia lasting into the earliest Silurian.

203 ment (RD) in her left eye, 3 years after the last intra-arterial chemotherapy (IAC) injection.

204 Last, kinomorph dynamics are shown to provide a centimet

205 tPA within 4.5 hours from the time they were last known to be well at Get With The Guidelines-Stroke

206 Long-lasting, latently infected resting CD4(+) T cells are th

207 ciation studies (GWAS) relevant genes in the last layer, and to a successively lesser degree in the m

208 (NC3) Up to rescaling, the last-layer classifiers collapse to the class means or in

209 ent asthma-like disease traits that peak and last long after active viral infection is cleared.

210 ng stimulus, juv ELE and juv-adol ELE formed lasting long-term memory for an object location memory t

211 he time elapsed between the first day of the last maternal menstrual period and the time at imaging)

212 ral/IV 5-day area under curve from time 0 to last measurable concentration (AUClast), percentage long

213 During the last menstrual period to 90 days postpartum, 56% of wome

214 ghlighting the advantages of variants of the last-mentioned procedure, and the utility of the various

215 r and with respect to the TC record over the last millennium, and: (2) MDRSST is the dominant climate

216 st actions, supra-linear responses, and long-lasting molecular switches.

217 a are more likely to have "complex" surgery" lasting more than 30 minutes.

218 I, 10.5% [CI, 4.2% to 19.8%]), prescriptions lasting more than 7 days (median ARI, 4.5%), and higher

219 contact lengths, which stabilize to produce lasting morphogenetic changes.

220 signal intensity ratio between the first and last MR study was -0.0275+/-0.1917 (not significantly di

221 ween the ratio in the first MR study and the last MR study.

222 Last, Neurog2 does not have cross-inhibitory effects on

223 The last of the 6 who required reoperation was in the elevat

224 ENKTL was enrolled on Feb 15, 2007, and the last on May 26, 2017.

225 Immunosuppression lasted only for the duration of the uterus graft.

226 management is suggested, with surgery as the last option.

227 amongst unvaccinated animals born after the last outbreak indicates likely viral circulation during

228 y were consistent irrespective of time since last PCI.

229 We previously identified that long-lasting periods of severe postictal hypoperfusion/hypoxi

230 psies from 121 patients with persistent/long-lasting persistent AF (group 1; 59 males; 60+/-11 years;

231 Maturation is the last phase of heart development that prepares the organ

232 crosslinked HD/Se hydrogel network and long lasting photothermal efficacies can be maintained for ca

233 growing number of survivors experience long-lasting physical impairments.

234 Levels of long-lasting, pp65-specific T cells with effector memory phen

235 After the last procedure (hybrid neurosurgery) the patient, in veg

236 inib led to prolonged clinical benefit and a lasting radiographic and metabolic response.

237 patients with median time from discharge to last recorded follow-up of 30 days (interquartile range

238 involves a protein-synthesis-dependent long-lasting reduction in GABA release.

239 The Iberian Peninsula was the last refuge of Neanderthal populations as modern humans

240 It is often related to the breakdown of the last relevant directed catalytic cycle within a dynamica

241 red resistance to colistin, an antibiotic of last resort used in treating multi-drug resistant bacter

242 ble class of drugs and often therapeutics of last resort.

243 Colistin is a last-resort antimicrobial used for the treatment of huma

244 ony-forming units, and infections are rapid, lasting roughly between 1 d and 3 d in the wild.

245 amples per person, median time from first to last sample, 4.3 years).

246 nduction chemotherapy and radiotherapy after last SCT.

247 The date of the last search was August 27, 2018.

248 therapy has progressively decreased over the last several decades in high-income countries, in circum

249 d to the use of a select few lyases over the last several decades, limiting the types of C-C bond-for

250 Impressive progress has been made over the last several years toward understanding how almost every

251 Despite significant progress over the last several years, many challenges and associated resea

252 4-8 millimetres in surface displacement that lasted several months and spanned thousands of kilometre

253 Last, simulations indicated that the presence of RBD nea

254 Last, situations specific to surgical populations are ad

255 mRNA translation represents the last step of genetic flow and primarily defines the prot

256 ansferase (ICMT) is the unique enzyme of the last step of posttranslational prenylation processing pa

257 red DNA (T-DNA) into the plant genome is the last step required for stable plant genetic transformati

258 ockdown measures caused substantial and long-lasting structural changes in the mobility network.

259 of the study, of whom 691 (81%) received the last study treatment at week 50.

260 ernational challenge, but it will not be the last such threat.

261 n of local PV(+) interneurons induces a long-lasting suppression of GABAergic synaptic transmission,

262 First, mu-opioids induce a long-lasting suppression of inhibitory synaptic transmission

263 with allergy, anti-IL-4Ralpha provided long-lasting suppression of the IgE recall response beyond an

264 ns have appeared in the literature since the last survey of this broad field in Chemical Reviews (Che

265 s that have been made in this field over the last ten years, focusing exclusively on first-row transi

266 al nerves have increased considerably in the last ten years.

267 and then become more quiescent for a period lasting tens of seconds.

268 kely to be more frequent, severe, and longer lasting than they have been in recent decades, but droug

269 hypoxia (10% inspired O(2) , n = 9) for the last third of gestation (105-138 days of gestation (dG);

270 trauterine conditions experienced during the last third of pregnancy.

271 m whereby adversity during puberty can enact lasting transcriptional control that manifests only duri

272 cells would be essential for meaningful and lasting treatments.

273 ation of carbonyl compounds emerged over the last two decades as a straightforward method for the for

274 Over the last two decades, iridium catalysis has evolved as a val

275 In the last two decades, polyPs have been primarily viewed as l

276 In the last two decades, the field has grown from a proof of co

277 In the last two decades, there has been considerable focus on t

278 acterization techniques that happened in the last two decades.

279 ility with multi-decadal resolution over the last two millennia is investigated using new records of

280 ates made over the seven releases during the last two years.

281 Dating back to the last universal common ancestor, P-loop NTPases and Rossm

282 he ERRbeta ligand-binding domain remains the last unsolved ERR structure and also one of only a few u

283 widely expressed (5x more cells) and longer lasting (up to 3 hr) than rats.

284 ession (<200 copies per mL) was based on the last viral load in the year preceding elicitation, and v

285 ups to 73.5 letters (P = 0.010 compared with last visit before surgery) and 67.2 letters (P < 0.001 c

286 y) and 67.2 letters (P < 0.001 compared with last visit before surgery), respectively.

287 ange; 5 months-14 years) and the mean age at last visit was 11.3 +/- 6.5 years.

288 wth rate for each eye based on the first and last visit.

289 waves, inner spiral rainbands trigger longer lasting wave trains on the front side of the tropical cy

290 At last, we demonstrate the utility of these tools by exami

291 Last, we demonstrated that genetic induction of lipid ca

292 Last, we discuss proteome persulfidation (S-sulfuration)

293 Last, we find that engineered waterways, whose emissions

294 Last, we identify the need for improved tools to identif

295 Last, we showed that IL-6 and C-reactive protein serum c

296 Last, while phylogenetic analysis indicates a bat origin

297 Premature-born adults exhibit lasting white matter alterations as demonstrated by wide

298 ous system (CNS) malignancies are often long-lasting without any clinical recourse.

299 ometry has undergone a rapid progress in the last years due to instrumental improvements leading to a

300 In the last years, deep learning has provided robust automated