ライフサイエンスコーパス: later stage of

1 arly stage of 2-dimensional (2D) growth to a later stage of 3D growth, despite the underlying variabi

2 ize the need to evaluate their roles through later stages of a tree's life cycle.

3 During the later stages of a trial, the motor imagery for a particu

4 rly disseminated Lyme disease but not in the later stages of active infection.

5 e/tissue repair responses prevail during the later stages of acute liver failure where elevated level

6 a protective and reconstructive way even in later stages of AD.

7 he dorsal striatum, a region associated with later stages of addiction, craving, and cue-induced rela

8 The role of lipins at later stages of adipogenesis, when cells initiate the fo

9 AP), premature senescence emerged, impairing later stages of adipogenesis.

10 y shifted the lag time with little effect on later stages of aggregation.

11 of Th2 immune responses, whereas its role at later stages of allergic disease may not be as critical

12 AL2 acts independently of VPS33B/VPS16B at a later stage of alpha-granule biogenesis.

13 In the later stages of ALS, pain can be severe enough to requir

14 ntly of amyloid pathology, especially in the later stages of Alzheimer's disease.

15 f identified differences were consistent for later stages of an outbreak.

16 more cases of COVID-19, particularly in the later stages of an unmitigated epidemic.

17 d that VvMYBA is a positive regulator of the later stages of anthocyanin synthesis, modification, and

18 ng of the pathological processes involved in later stages of aortic aneurysm progression.

19 OM acts early, whereas BIG ARF-GEFs act at a later stage of apical hook development.

20 BamA and therefore appeared to function at a later stage of assembly.

21 ed for its positive reinforcing effects, but later stages of AUD are characterized by drinking to all

22 Here, we identify that mTORC1 inhibits later stages of autophagy by phosphorylating UVRAG.

23 in signaling in sensory neurons to mediate a later stage of axon development - arborization in the ta

24 ate motoneuron development, particularly the later stages of axon branch and dendrite formation.

25 ent on the Nox2 isoform of NADPH oxidase, at later stages of B cell activation (6-24 h) ROS were gene

26 lar sources and plays a critical role at the later stages of B cell activation by promoting sustained

27 In the chicken bursa, the later stages of B cell development occur in the presence

28 reveals selective TACI haploinsufficiency at later stages of B-cell development.

29 ent to catheter biomaterials, and defects in later stages of biofilm development were indicated.

30 At later stages of blood flow, Foxc2 and calcineurin-Nfat s

31 However, their role in later stages of brain development, particularly in the r

32 olonization, the role of BCR ligation in the later stages of bursal B cell lymphopoiesis remains elus

33 A similar analysis of later stages of C. elegans development has been challeng

34 are not medically detected or visible until later stages of cancer development.

35 e, increased BOP1 expression was observed at later stages of CaP progression, coinciding with a local

36 ion, and is transcriptionally upregulated at later stages of cardiac differentiation.

37 ediately after stimulus onset, followed by a later stage of category-specific perceptual processing.

38 nt to the active cluster and of the early to later stage of cell cycle, with marked increase in expre

39 It was also observed that mAbs harvested at later stages of cell culture contained higher concentrat

40 The later stages of cell division include the formation of t

41 cation within the septal aperture during the later stages of cell division.

42 Blocking NMDA receptors during later stages of circuit development did not disrupt segr

43 Patients with later stages of CKD had lower renal elasticity values, i

44 try inhibitors, with a focus on drugs in the later stages of clinical development.

45 ly show promising results in rodents fail in later stages of clinical trials.

46 By contrast, at later stages of clone growth, clones change their growth

47 lly accommodates only smaller sample sets at later stages of clone selection.

48 ependent excessive cell proliferation in the later stages of collateral remodeling correlates with im

49 However, analysis of Lhx2 function at later stages of cortical development has been hampered b

50 emonstrate a vital role for JNK signaling at later stages of corticogenesis, when interneurons transi

51 At later stages of cytokinesis, these various rings appeare

52 nd the neural correlates associated with the later stages of decision making (e.g., motor response ge

53 in early visual cortex or via competition at later stages of decision-making and response selection.

54 of hippocampal atrophy is well known in the later stages of decline, the ability of fornix-hippocamp

55 ating that Trps1 functions as a repressor of later stages of dentinogenesis, we provide functional si

56 s rapid gene expression and functions at the later stages of development and differentiation.

57 In addition, later stages of development and the timing of emergence

58 h in-depth phenotyping of the fourth leaf at later stages of development in 197 recombinant inbred li

59 ides with carotenoid accumulation during the later stages of development of underground storage roots

60 nterestingly, ablation of Mef2 expression at later stages of development showed MEF2 to be more dispe

61 that express both Pax6 and Gsx2, but during later stages of development this boundary is largely ref

62 At later stages of development, PGE2 acting via the ep4a re

63 However, during later stages of development, smad2 and smad3 became stro

64 expected downregulation of pax2a and pax8 at later stages of development, suggesting complex regulato

65 eterogeneous range of migratory behaviors at later stages of development, with the acquisition of com

66 synaptic refinement in the visual system at later stages of development.

67 pines, but little is known about its role in later stages of development.

68 mplantation lethality, preventing studies at later stages of development.

69 rted megabase-scale CNVs in neurons arise at later stages of development.

70 s in vitro, as disease commonly manifests at later stages of development.

71 ng endoderm with complete epithelial loss at later stages of development.

72 y is unchanged at the onset but decreases at later stages of diabetes.

73 y increased chitin production that occurs in later stages of diatom growth.

74 yotube fusion, and, ultimately, hypertrophy (later stage of differentiation).

75 nished in tumors derived from B cells at the later stages of differentiation (with complete loss in P

76 further study into the mechanisms governing later stages of differentiation and the acquisition of f

77 that although fusion oncogene expression in later stages of differentiation can transform mesenchyma

78 In addition to Dlx6's expression at later stages of differentiation of many basal ganglia nu

79 that kif3c, although redundant with kif3b at later stages of differentiation, is not active early in

80 position and affected gene expression at the later stages of differentiation.

81 effects are not observed in adult B cells in later stages of differentiation.

82 ving broken granules to smaller particles at later stage of digestion.

83 At moderate and later stages of disease (LMCI/AD), hypometabolism become

84 strategies for secondary prevention aimed at later stages of disease are also needed.

85 es and importantly, their distinction in the later stages of disease from genetically mediated or acq

86 Whether these cells remain key players in later stages of disease is unknown.

87 pression of IL-13Ralpha2 was associated with later stages of disease progression and poor outcome in

88 ed inhibition causes more severe myopathy at later stages of disease progression potentially through

89 e lung during acute infection as well at the later stages of disease resolution, recovery, and immune

90 s to most people remaining undiagnosed until later stages of disease when prognosis is poor and treat

91 erebral malaria, but it is less effective in later stages of disease when the host inflammatory respo

92 aggravated disease course, especially in the later stages of disease, but also importantly resulted i

93 to independently drive neuroinflammation at later stages of disease.

94 gement and identification studies during the later stages of drug discovery and even in a clinical se

95 ring the peak, and decline in numbers during later stages of EAE.

96 EAU, since eliminating microglia during the later stages of EAU had little effect, indicating that t

97 n of DGK decreased PA production only at the later stages of EGF stimulation, suggesting that PLD2 pr

98 ypass translational arrest can be stopped at later stages of elongation while translation of some pro

99 stages, and then TET1 is a key regulator at later stages of embryo development.

100 for primordial germ cell development during later stages of embryogenesis, is essential for Xenopus

101 During later stages of embryogenesis, Prox1 appears to regulate

102 extracellular calcite-protein composites) at later stages of embryonic development.

103 at the mutation causes aberrant movements in later stages of endocytosis, consistent with a scission

104 uilliform body plan is gradually lost during later stages of evolution, gaits are evolved for the fin

105 infection, the endodermis is degraded during later stages of feeding site development, indicating per

106 ediated sugar release was predominant in the later stages of fermentation, which explains why higher

107 e to detect both glucose and fructose in the later stages of fermentation, while HPLC was not.

108 ction of small oligomers is still present at later stages of fibril assembly.

109 ehog signalling drive disease progression in later stages of fibrotic diseases.

110 erence for interacting with clients at their later stages of folding.

111 , and thus oil accumulation, correlates with later stages of fruit expansion.

112 chanisms of accumulation of ascorbate in the later stages of fruit ripening.

113 ht on the role of oxidative processes in the later stages of fruit ripening.

114 At later stages of GE, unreacted Ag inclusions phase segreg

115 ome susceptible to ZIKV infection as well at later stages of gestation.

116 itment and mobilization were impaired at the later stage of GSIS.

117 interferon-stimulated genes observed during later stages of hantavirus infection fail to combat the

118 tured with extensive callus formation in the later stages of healing.

119 e proliferation and morphogenesis during the later stages of heart development.

120 patients, suggesting that they may appear in later stages of HHT development.

121 , their broad and effective use for modeling later stages of human brain development and disease is h

122 of DNA modification and transcription in the later stages of human life.

123 ease in myofiber DNA content observed at the later stage of hypertrophy was associated with a signifi

124 erbating these changes are documented during later stages of hypertrophy (usually termed pathological

125 f LSD1, causing HIF-1alpha downregulation in later stages of hypoxia.

126 ity of oligodendrocytes and/or astrocytes at later stages of illness.

127 ntiation of imINPs due to loss of Earmuff at later stages of imINP development.

128 lvage rates were comparable at the early and later stages of implementing the twinning program.

129 and this protective effect was preserved at later stages of infarct development.

130 This protective effect was preserved at later stages of infarction as well as in elderly mice.

131 This protective effect was preserved at later stages of infarctions as well as after permanent s

132 At a later stage of infection (day 7), abscess resolution and

133 intestinal colonization and virulence at the later stage of infection, in comparison with the parent

134 tachyzoite growth in their brains during the later stage of infection, were infected, and one group r

135 but switched to amyloid-like structures at a later stage of infection.

136 cally and that much of the damage during the later stages of infection is due to the interactions of

137 regulated by SA and JA during the early and later stages of infection, respectively.

138 nt postexposure treatments are inadequate at later stages of infection, when high levels of anthrax t

139 y inhibited mTOR-regulated autophagy even at later stages of infection, whereas there was a clear ind

140 xhibited impaired bacterial clearance during later stages of infection, which was associated with alt

141 ey developed significantly larger lesions at later stages of infection, with a more pronounced inflam

142 At early but not at later stages of infection, WT mice had higher circulator

143 d significantly more severe pathology in the later stages of infection.

144 pillover into the downstream LNs involved at later stages of infection.

145 inhibited IFITM protein accumulation in the later stages of infection.

146 immune dysfunction and viral persistence at later stages of infection.

147 tes with anti-inflammatory/M2 macrophages at later stages of infection.

148 ater, probably to prevent suppression during later stages of infection.

149 However, they could affect pathogenesis at later stages of infection.

150 iring infection from someone in the chronic (later) stage of infection.

151 At later stages of infiltration, T-cell motility accelerate

152 as well as enhanced extravasation during the later stages of inflammation.

153 e increased accumulation observed during the later stages of inflammation.

154 RNAP exit kinetics from complexes stalled at later stages of initiation (e.g., from a 7-base transcri

155 more marked repression of growth during the later stage of leaf development.

156 r expression pattern and function diverge at later stages of leaf development.

157 learned the skill; continued practice during later stages of learning (i.e., after motor kinematics h

158 rebellar excitability (CBI) changes, whereas later stages of learning will result in M1 LTP-like plas

159 ific in their temporal structure compared to later stages of learning.

160 O1 and Sp1 formed complexes during early and later stages of lens development.

161 paradoxically, changes to convergence in the later stages of life.

162 growth factor signaling is activated in the later stage of limited OPC differentiation.

163 an increase of C/EBPbeta-HDAC1 complexes at later stages of liver cancer.

164 d downregulation of MHC-I was evident during later stages of lytic replication.

165 The results show that gata3 is critical for later stages of mammalian auditory system development wh

166 rs and sizes increased, more notably, during later stages of maturation than the early stages.

167 (HSP70) is constitutively expressed and, at later stages of maturation, translocates into the nucleu

168 s a transient activation of caspase-3 at the later stages of maturation.

169 that curtail their colocalization during the later stages of maturation.

170 , and lactate decreased significantly at the later stages of meal challenge in RYGB surgery subjects

171 ome number abnormalities, whereas those from later stages of melanoma did.

172 ntially facilitating earlier, but repressing later, stages of metastasis by regulating an EMT-MET axi

173 e in wild-type plants, it remains present in later stages of mitosis in ccs52a2-1 mutant plants, mark

174 During later stages of mitosis, p-Moesin localization shifts mo

175 regulation of cortical contractility in the later stages of mitosis.

176 Previously, the later stages of monkeypox infection were defined, but th

177 ch indicated that the defect occurred during later stages of monocyte development.

178 At the later stages of MS and experimental autoimmune encephali

179 In later stages of MS, phase rim lesions continue to smolde

180 male patients' accelerated disease course at later stages of MS.

181 active lesions are primarily related to the later stages of multiple sclerosis; however, the occurre

182 At later stages of myelination, Scribble acts to negatively

183 K signaling is required for myoblast fusion (later stage of myogenesis).

184 dentity and maintain long-term viability for later stages of neural development, including axon outgr

185 ices from 2 month old mhAPP mice, whereas at later stage of neurodegeneration (6 month) basal synapti

186 First, during the later stages of neurogenesis (P18), neurons make up most

187 ency of cortical plate-directed migration at later stages of neurogenesis concomitant with the start

188 rebrain after neural tube closure and during later stages of neurogenesis populate regions of the dev

189 omomeric nAChRs appear to be involved in the later stages of nicotine dependence.

190 The later stages of nodule development require the activatio

191 e mandiblar stylets become more prominent in later stages of nymphal development, while odontoid prot

192 nt metabolic capabilities, especially during later stages of nymphal feeding.

193 suggests that the source rock represents the later stage of Oceanic Anoxic Event 2.

194 ding reduction in craniofacial plasticity at later stages of ontogeny.

195 riking contrast, the absence of dTBCB during later stages of oogenesis causes major defects in cell p

196 al areas and an increasing importance toward later stages of outbreaks in both urban and rural settin

197 imulation study corroborated the pattern for later stages of outbreaks.

198 However, its function at later stages of pancreatic carcinogenesis remains poorly

199 During later stages of pancreatitis, C5-deficient mice and mice

200 rnal scaffolding protein, which mediates the later stages of particle morphogenesis, restored viabili

201 rsed processing also plays a central role in later stages of perception.

202 roteins that also reduce trichome density at later stages of plant development.

203 but is necessary for proto-NM renewal during later stages of pLL formation.

204 tively high yield whereas none are formed at later stages of polymerization.

205 mplex permits up-regulation of Bbc3 during a later stage of positive selection, inducing thymocyte ap

206 l ability factor that is expressed mostly at later stages of practice and additional task-specific fa

207 bcortical amyloidosis, indicating earlier or later stages of preclinical AD, was associated with grea

208 transcription was markedly repressed in the later stages of pregnancy and immediately recovered afte

209 During later stages of pregnancy, placental trophoblasts serve

210 of circulatory decompensation usually in the later stages of pregnancy, with a less severe impact on

211 l infections may disrupt fetal protection in later stages of pregnancy.

212 We demonstrate that CIN is not preserved at later stages of prenatal development, and that de novo n

213 In the later stages of progression, HNSCC with and without noda

214 ild-type Arabidopsis, suggesting problems in later stages of PsaA/B protein expression in the two var

215 a complex with Fls2/Fls3 and is important at later stages of PTI in the apoplast.

216 tion, but it is assumed to be minimal before later stages of puberty.

217 E93 is expressed in MB neuroblasts during later stages of pupal development only, which includes t

218 During the later stage of reactor operation, higher expression of a

219 f proliferation but governs proliferation at later stages of regeneration.

220 ombine with targeted therapies impacting the later stages of remodeling and vessel maturation are exp

221 ly kidney development, but their role during later stages of renal tubule maturation is not well unde

222 fness and increased force to fracture in the later stages of repair.

223 s relying on X-rays which are only useful at later stages of repair.

224 in matching of memory representations or in later stages of response selection.

225 ne all increased dramatically, especially at later stage of ripening, whereas the changes for alpha-i

226 tion, PAR2 was upregulated especially at the later stage of RSV infection.

227 During later stages of seed development, these two SADs, togeth

228 However, the later stages of segment patterning, regulated by the "pa

229 e cus2 mutant, but are lost progressively at later stages of sepal development, indicating that CUS2

230 In the later stages of sepsis, epigenetic modifications accompa

231 t nitric oxide synthase 2 levels decrease in later stages of sepsis, whereas levels and activity of s

232 tent with the specific expression of AMD1 at later stages of sexual development.

233 Later stages of spectral evolution are consistent with h

234 Although the role of mitochondria in later stages of spermatogenesis has been investigated in

235 fields, and these fields might survive into later stages of stellar evolution, but information has b

236 sing within the somatosensory network in the later stages of stimulus processing.

237 e receptor signaling, LPL is critical to the later stages of synapse maturation and cellular polariza

238 sponse is instrumental in the development of later stages of syphilis.

239 Moreover, alterations in H2A.Z binding at later stages of systems consolidation suggest that this

240 -kDa FK506-binding protein), which acts at a later stage of the chaperone cycle.

241 rent treatment, especially when initiated at later stage of the disease, does not produce completely

242 improved motor function of mdx mice at that later stage of the disease.

243 an area with limited community spread at the later stage of the study Universal PPE is protective in

244 s-activated conditions can also intervene at later stages of the aggregation pathway to further delay

245 e effects of CHL have been mainly studied at later stages of the auditory pathway, but early stages r

246 hearing loss could cause similar changes at later stages of the auditory pathway, which could contri

247 However, they showed severe defects in later stages of the biogenesis process, presumably durin

248 to provide vital repolarizing current during later stages of the cardiac action potential.

249 is removed by the sirtuins Hst3 and Hst4 at later stages of the cell cycle.

250 newly synthesized CENP-A is deposited during later stages of the cell cycle.

251 ition of the stress and was not required for later stages of the cell death program.

252 At the later stages of the disease ambulation often becomes dif

253 Later stages of the disease are characterized by inflamm

254 could inhibit allergic responses during the later stages of the disease process, namely allergen re-

255 ndings, which generally do not present until later stages of the disease when the condition is diffic

256 iorgan donors with T1D (both at onset and at later stages of the disease) and not in that of multiorg

257 Current therapies for DR address only the later stages of the disease, are invasive, and have limi

258 on; (c) higher fitness clones are present in later stages of the disease, indicating a progressive cl

259 In later stages of the disease, the pathology extends to th

260 ry phenotype would be most beneficial in the later stages of the disease.

261 ading to lymphatic contraction arrest at the later stages of the disease.

262 invasion and dissemination of tumor cells at later stages of the disease.

263 ts with CKD develop hyperphosphatemia in the later stages of the disease.

264 beta will have major clinical effects in the later stages of the disease.

265 TIGIT receptor expression did not persist to later stages of the disease.IMPORTANCE Given the synergi

266 VEP amplitude that was most striking in the later stages of the disorder.

267 r had an increasingly negative impact in the later stages of the disorder.

268 phase of recycling and this has an impact on later stages of the endo-exocytic pathway.

269 in the transfer of Pse onto flagellin at the later stages of the glycosylation pathway.

270 ution in introduced ranges is a mechanism at later stages of the invasion process, the introduction o

271 an active role for this molecule in driving later stages of the multistep adhesion cascade.

272 at H5N2 viruses isolated from poultry in the later stages of the outbreak had higher infectivity and

273 While the later stages of the pathways are well elucidated, the mo

274 ate chemistry becomes less active during the later stages of the pollution episodes.

275 ptations and political complexity during the later stages of the pre-Columbian era.

276 , adaptation time constants become longer at later stages of the processing hierarchy, resulting in p

277 Yet signaling pathways that regulate later stages of the productive gammaherpesvirus replicat

278 To permit examination of later stages of the reaction sequence to 2, the (15)N-la

279 modest electrophysiological recovery during later stages of the regeneration process.

280 ation to support fatty acid synthesis in the later stages of the stress response.

281 Few estimates were available for later stages of the treatment cascade.

282 ssion facilitates DNA replication and allows later stages of the viral life cycle to proceed in the a

283 specially under serum-free conditions in the later stages of the viral replication cycle.

284 ly stages of the cell cycle, or large and in later stages of their cell cycle.

285 tatic interactions both in the early and the later stages of this model coupled folding and binding p

286 gions previously shown to be demyelinated in later stages of this syndrome.

287 portant role for the adapter protein ShcA in later stages of thymic T cell development and in periphe

288 Later stages of tooth development were characterized by

289 , because Pitx2 is also a major regulator of later stages of tooth development, especially during ame

290 ator Met-tRNA(i)(Met) on the ribosome in the later stages of translation initiation, gating entrance

291 significant increases in methanogens at the later stages of treatment that correlated with increases

292 proteins such as DNA-PK and CHK1 during the later stages of tumor development.

293 nction during astroglial immortalization vs. later stages of tumor development.

294 be subclonal, implying subtype divergence at later stages of tumor evolution.

295 ed prior to cancer onset, suggesting that at later stages of tumor progression GSH becomes dispensabl

296 eased activation of STAT3 and ERK during the later stages of tumorigenesis.

297 logy disruption, and apoptosis inhibition in later stages of viral replication.

298 entry, whereas lower concentrations block a later stage of virus life cycle.

299 from the nucleus to the cytoplasm during the later stages of virus replication.

300 hosphorylates and inactivates ULK1 (S757) at later stages of ZIKV infection, suggesting a link betwee