ライフサイエンスコーパス: lateral diffusion

1 s (alpha7-nAChRs) access synaptic domains by lateral diffusion.

2 at percolation is not the factor controlling lateral diffusion.

3 ranes, most DAF molecules exhibited Brownian lateral diffusion.

4 d receptor from the lipid-water interface by lateral diffusion.

5 rmation on the details associated with lipid lateral diffusion.

6 t has a slightly higher activation energy of lateral diffusion.

7 nter-NAP-22 interactions markedly reduce its lateral diffusion.

8 hase DSPC domains that acted as obstacles to lateral diffusion.

9 s, in which the ligands were capable of free lateral diffusion.

10 their proteins are dynamically recruited by lateral diffusion.

11 by dehydration, showing a 6-fold decrease in lateral diffusion.

12 ntion of the resulting peptides with minimal lateral diffusion.

13 very after photobleaching is used to measure lateral diffusion.

14 e membrane-associated cytoskeleton modulates lateral diffusion.

15 s with a higher rate of Brownian tumbling or lateral diffusion.

16 d nanoclustering and concomitantly increased lateral diffusion.

17 ne to two orders of magnitude enhancement in lateral diffusion.

18 of magnitude lower than accepted values for lateral diffusion (10 (-8)-10 (-7) cm (2)/s).

19 of magnitude lower than accepted values for lateral diffusion (10(-8)-10(-7) cm2/ s).

20 Deleting the ABCC4 PDZ motif accelerates lateral diffusion ~4-fold, halves protein half-life, and

21 (2) in membrane microdomains with restricted lateral diffusion, a hypothesis providing a mechanism fo

22 etachment may include release from the cell, lateral diffusion across the cell surface, or endocytosi

23 chemical and electrical synapses, potassium lateral diffusion alone can generate and synchronize zer

24 It has been shown that potassium lateral diffusion alone is sufficient for synchronizatio

25 ustained activity can propagate by potassium lateral diffusion alone with a velocity of approximately

26 e of turnover within the midzone and limited lateral diffusion along spindle MTs.

27 rs between the segments significantly reduce lateral diffusion along the axon.

28 by two diffusion coefficients, D( )(lip)for lateral diffusion along the lipid lamellae and D( )(lip)

29 Lateral diffusion analysis indicates apparent anomalous

30 K(+) or Na(+), consequently leading to lower lateral diffusion and a higher compressibility modulus,

31 sociations that apparently restrict integrin lateral diffusion and accumulation into clusters, thus c

32 , an hCG antagonist, also exhibit restricted lateral diffusion and are confined in nanoscale membrane

33 s treated with 100 nm hCG exhibit restricted lateral diffusion and are confined in small, nanometer-s

34 Thus, activity-dependent regulation of KCC2 lateral diffusion and clustering allows for a rapid regu

35 size of single cells and acted to reduce the lateral diffusion and confine the movement of compounds

36 In addition, lateral diffusion and confinement exchanges surface memb

37 introduce a simple correction procedure for lateral diffusion and demonstrate how the effect of late

38 le from cholesterol-free bilayers, including lateral diffusion and electron density.

39 es KCC2 surface expression by increasing the lateral diffusion and endocytosis of the transporter.

40 ess stabilized at synapses, increasing their lateral diffusion and endocytosis.

41 f tranverse diffusion through the tissue and lateral diffusion and exchange with skin appendages is p

42 in architecture, a change that also retarded lateral diffusion and induced large clusters of HLA-I.

43 tivation directly correlated with restricted lateral diffusion and integrin immobilization.

44 s issue of Neuron, Hoerndli et al. show that lateral diffusion and kinesin-mediated transport move AM

45 The coupling of both lateral diffusion and membrane order was monitored as a

46 rption spectroscopies, we characterize lipid lateral diffusion and membrane phase structure as a func

47 dy, we examine the phase behavior as well as lateral diffusion and percolation in the region of coexi

48 Mechanisms regulating lateral diffusion and positioning of glutamate receptors

49 receptor conformation and affinity and/or by lateral diffusion and receptor clustering.

50 membrane recruitment, 5-HT(1B) transport via lateral diffusion and temporal confinement to inhibitory

51 sing with a typical lifetime that depends on lateral diffusion and the dynamics of barriers.

52 ed into the membrane function as barriers to lateral diffusion and were used to isolate the proteins

53 st interestingly, we show that the anomalous lateral diffusion and, consequently, the binding to gela

54 it is still a challenging task to quantify (lateral) diffusion and estimate local dynamics of protei

55 temporary confinement by dynamic barriers to lateral diffusion, and dispersion of the clusters by dif

56 nt probes of surface lipid fluidity, surface lateral diffusion, and interfacial polarity, and by thei

57 en apparently by mass action and short-range lateral diffusion, and locally delivered AMPARs remained

58 into account lateral diffusion, barriers to lateral diffusion, and vesicle traffic to and from the p

59 Endocytosis, exocytosis, and lateral diffusion are key mechanisms for AMPA receptor t

60 of the lipid headgroup, ranging from a fast lateral diffusion at some membranes to the escape of pro

61 d hormone displays limited mobility and slow lateral diffusion at the cell surface.

62 Dab2 interacts with TbetaRI to restrict its lateral diffusion at the plasma membrane and enhance its

63 Confinement required the formation of a lateral diffusion barrier in the form of a distinct doma

64 channel subtypes at CNS nodes and provide a lateral diffusion barrier that, even in the absence of t

65 In many cell types, lateral diffusion barriers compartmentalize the plasma m

66 es and is retained in the mother cell by the lateral diffusion barriers present at the bud neck.

67 Our computer model takes into account lateral diffusion, barriers to lateral diffusion, and ve

68 tegrates three ubiquitous receptor processes-lateral diffusion, basal ligand-independent activation,

69 their externalization, internalization, and lateral diffusion between the synaptic and extrasynaptic

70 t actin disruption not only increases LYVE-1 lateral diffusion but also enhances hyaluronan-binding a

71 Most GPCRs were delivered to dendrites via lateral diffusion, but one GPCR, the serotonin 1B recept

72 We propose a model for how lateral diffusion can be coupled in opposite leaflets an

73 These simulations suggest that potassium lateral diffusion can play an important role in the sync

74 However, it is not yet known whether the lateral diffusion can, by itself, induce seizure activit

75 changing the stability of actin barriers to lateral diffusion changes cluster lifetimes.

76 demonstrated that PAH[4]s can form, through lateral diffusion, clusters in lipid membranes that prov

77 erent temporal shear gradients) on the lipid lateral diffusion coefficient (D) in the apical membrane

78 The mean lateral diffusion coefficient (D) of M2 was 4.4 +/- 1.0

79 rease by 10% upon drying/rehydration and the lateral diffusion coefficient decreased from 2.2 to 1.6

80 after photobleaching was used to measure the lateral diffusion coefficient in single supported bilaye

81 l expression is presented that describes the lateral diffusion coefficient in terms of the solute's m

82 n the kinetics of migration, the F-alphaAQP1 lateral diffusion coefficient in the membrane projection

83 cell membrane is 66 +/- 10% and the average lateral diffusion coefficient is (3.1 +/- 0.5) x 10(-11)

84 The lateral diffusion coefficient is 8 x 10(-8) cm(2)/s.

85 stituted t-SNARE was laterally mobile with a lateral diffusion coefficient of 7.5 x 10(-9) cm(2)/s in

86 D, the lateral diffusion coefficient of N-(7-nitrobenzoyl-2-oxa

87 There was no correlation of the lateral diffusion coefficient with solvent viscosity, a

88 This increase in the lateral diffusion coefficient, D, is characteristic of m

89 A clear molecular weight dependence of the lateral diffusion coefficients in DMPC bilayers was obse

90 eaching (video-FRAP) was used to measure the lateral diffusion coefficients of a series of nine fluor

91 A method is presented for measuring the lateral diffusion coefficients of exogenously applied co

92 ation is supported by a strong dependence of lateral diffusion coefficients on protein density on the

93 The bolalipid lateral diffusion coefficients, determined by fluorescen

94 on Fluorescence (TIRF) microscopy to measure lateral diffusion coefficients.

95 The Tempo lateral diffusion constant of (1.5 +/- 0.7) x 10(-4) cm2

96 The lateral diffusion constants of 1-palmitoyl-2-oleoyl-sn-g

97 Within error, the lateral diffusion constants of these engineered construc

98 heoretical studies have shown that potassium lateral diffusion coupling (i.e., diffusive coupling) ca

99 e simulation results show that 1), potassium lateral diffusion coupling is crucial for establishing e

100 We tested the hypothesis that potassium lateral diffusion coupling is responsible for the coupli

101 diction, but strongly suggest that potassium lateral diffusion coupling, a physiological realization

102 ged into brain phosphatidylcholine vesicles, lateral diffusion decreased in both leaflets.

103 two streams and allowing mixing to occur by lateral diffusion did not compare well.

104 By lateral diffusion, DiI also stains membrane structures,

105 r monotopic topology, enabling their passive lateral diffusion during LD emergence at the ER.

106 Lateral diffusion enables efficient interactions between

107 nal periodic array of asymmetric barriers to lateral diffusion fabricated from titanium oxide on sili

108 estabilizing D1R localization, via increased lateral diffusion followed by increased internalization

109 passive diffusion, conventionally involving lateral diffusion followed by membrane bilayer flip-flop

110 ing domains allow some colicins to search by lateral diffusion for binding sites on their OM transloc

111 ch as GluR1 homomers, to synapses likely via lateral diffusion from extrasynaptic sites.

112 f the model allows for PIP2 replenishment by lateral diffusion from neighboring dendrite membrane.

113 rmation in which axonal Na+ channels move by lateral diffusion from regions of Schwann cell contact,

114 receptors on the spines may occur either by lateral diffusion from release sites over nearby postsyn

115 d on trafficking of key membrane proteins by lateral diffusion from surface populations and by exocyt

116 crowding, and molecular interactions deviate lateral diffusion from the expected random walks.

117 t of brain SM, which decreased outer-leaflet lateral diffusion, had little effect upon lateral diffus

118 olving acquisition from the lipid bilayer by lateral diffusion have been proposed for hydrophobic sub

119 The lateral diffusion in bilayers is modeled with a multisca

120 ons, diffusion-limited processes, especially lateral diffusion in cell membranes and geometrical cons

121 romolecules are believed to hinder molecular lateral diffusion in cellular membranes.

122 ers move by vesicle diffusion, as opposed to lateral diffusion in continuous membranes.

123 et lateral diffusion, had little effect upon lateral diffusion in inner leaflets composed of dioleoyl

124 in the two leaflets) but did greatly reduce lateral diffusion in inner leaflets composed of PC with

125 g IFN-gammaR2 T168N-bound galectins restored lateral diffusion in lipid nanodomains and JAK/STAT sign

126 consistent with the function of barriers to lateral diffusion in maintaining MHC-I clusters.

127 B-P-Chol, although we found no difference in lateral diffusion in model membranes.

128 s (NMDAr) are known to undergo recycling and lateral diffusion in postsynaptic spines and dendrites.

129 lt and order, lipid rotational dynamics, and lateral diffusion in regions of leaflets that are opposi

130 lustrates the degree to which small-molecule lateral diffusion in stratum corneum-extracted lipids ca

131 nto dioleoylphosphatidylcholine (DOPC) GUVs, lateral diffusion in the bSM-containing outer leaflet de

132 Lateral diffusion in the gel, which had previously been

133 ort of integral proteins to the INM involves lateral diffusion in the lipid bilayer around the nuclea

134 ive transport across the luminal membrane or lateral diffusion in the lipid bilayer.

135 ne, both at room temperature and to decrease lateral diffusion in the membrane, at 4 degrees C.

136 The drug may access its binding site by lateral diffusion in the membrane, suggesting that other

137 Despite free lateral diffusion in the membrane, they showed no FTR ov

138 Lipid lateral diffusion in the outer hair cell plasma membrane

139 olecules in the contact site were capable of lateral diffusion in the plane of the phospholipid bilay

140 , trafficking of AMPARs to and from the PSD, lateral diffusion in the plane of the spine membrane, an

141 Lateral diffusion in the plasma membrane is obstructed b

142 ics between midbrain and striatum, mainly by lateral diffusion in the plasma membrane with only a lim

143 Interestingly, we found that the lateral diffusion in the PM was two times slower for B-C

144 This study revealed that AT1R lateral diffusion increased after binding to angiotensin

145 s (DGT) samplers, we show that the effect of lateral diffusion inside the sampler on the solute flux

146 The flux increase caused by lateral diffusion inside the sampler was determined to b

147 2) concentrations (C(a)) caused only limited lateral diffusion into the greased areas.

148 Lateral diffusion is also propagated to the diffusive bo

149 tide is located on the membrane surface, its lateral diffusion is characterized by a distribution of

150 biological meaning, (ii) that no noticeable lateral diffusion is induced during to sample preparatio

151 Modeling moreover revealed that lateral diffusion is key for the clearance of local Na(+

152 present in these microdomains, and that NaPi lateral diffusion is slowed down and NaPi aggregation/cl

153 suggest that membrane turnover, rather than lateral diffusion, is the main 'redeployment' route for

154 nd tether-pulling experiments to measure DAF lateral diffusion, lateral confinement, and membrane ske

155 lipid asymmetry, biological composition and lateral diffusion makes this method a powerful tool for

156 Lateral diffusion measurements in stratum corneum-extrac

157 Lateral diffusion measurements of IMM correlate with mic

158 Lateral diffusion measurements on cell membrane molecule

159 Here we present the first example of a lateral diffusion mechanism for the uptake of hydrophobi

160 So far, all transport proteins for which a lateral diffusion mechanism has been proposed function a

161 phosphorylation-dephosphorylation cycle and lateral diffusion modulated by clustering.

162 rfaces in monomeric form, but that following lateral diffusion, molecules ultimately reside within br

163 recovery after photobleaching studies on the lateral diffusion of a coexpressed receptor.

164 The lateral diffusion of a lipid and a protein probe at vary

165 We develop an expression for lateral diffusion of a nutrient, where the diffusivity i

166 pes, appear to compensate for the effects of lateral diffusion of activity attributable to dendritic

167 s stepwise recognition process is coupled to lateral diffusion of Ago2 along the target RNA, which pr

168 The influence of mobile phase on the lateral diffusion of an amphiphilic dye was studied for

169 F technique was established by investigating lateral diffusion of an amphiphilic tetradecane TEMPO de

170 o axon proximal segments as well as limiting lateral diffusion of ankyrinG-neurofascin complexes.

171 observable membrane defects and decrease in lateral diffusion of both lipids and proteins.

172 rably dynamic process, because it depends on lateral diffusion of BtuB and collisional interaction wi

173 cence recovery after photobleaching that the lateral diffusion of CD4 decreased 4-fold following sphi

174 Lateral diffusion of cell membrane constituents is a pre

175 Lateral diffusion of CO(2) was investigated in photosynt

176 after photobleaching analysis to measure the lateral diffusion of CXCR1-CFP, we found that interleuki

177 The lateral diffusion of DiI was the fastest for tetrahydrof

178 Lateral diffusion of DRD2 was observed following its ins

179 layers become disordered, allowing for some lateral diffusion of dyads within their own layer.

180 incorporated GM1 lipid alters the long-range lateral diffusion of fluorescently labeled probe lipids,

181 Lateral diffusion of GFP-tagged H2Ld molecules in the ER

182 iety of barriers and obstacles that slow the lateral diffusion of glycosylphosphatidylinositol (GPI)-

183 nerally accepted that gap junctions form via lateral diffusion of hemichannels following microtubule-

184 olecular dynamics (MD) simulations that show lateral diffusion of Hg atoms in graphene interlayer spa

185 Our study suggests that lateral diffusion of hydrophobic molecules is the modus

186 We show that the lateral diffusion of IFN-gammaR2 is confined by sphingol

187 ed in lipid bilayer dynamics, notably in the lateral diffusion of individual lipids.

188 Our findings suggest that the lateral diffusion of integrin ligands on cells may be an

189 o expectations, suggesting the importance of lateral diffusion of ions.

190 intricate coupling between conformation and lateral diffusion of LFA-1 and further underscores the c

191 To expedite lateral diffusion of lipid molecules without sacrificing

192 Lateral diffusion of lipids is significantly slower in t

193 elting phospholipid domains that inhibit the lateral diffusion of membrane components.

194 olecule localization is hampered by the fast lateral diffusion of membrane probes.

195 o widespread use of the technique to measure lateral diffusion of membrane proteins and lipids, and a

196 eleton has emerged as a key modulator of the lateral diffusion of membrane proteins.

197 ynein induced a significant reduction in the lateral diffusion of microtubule ends, distinct from the

198 lateral resolution of SPIM is limited by the lateral diffusion of minority charge carriers.

199 RFM image sequences, to account for both the lateral diffusion of molecules at the membrane and the c

200 Lateral diffusion of N-TOH in 1-palmitoyl-2-oleoyl-sn-gl

201 demonstrates that Na(+) influx causes rapid lateral diffusion of Na(+) within spiny dendrites.

202 lar vesicles, we showed a 2-fold decrease in lateral diffusion of NaPi protein and a greater than 2-f

203 ould be promoted by anisotropically enhanced lateral diffusion of oxygen along the midplane and by ju

204 ecreases annexin binding by compromising the lateral diffusion of phosphatidylserine, inhibiting the

205 Obstructed long-range lateral diffusion of phospholipids (TRITC-DHPE) and memb

206 Moreover, ezrin can limit the lateral diffusion of PI(4,5)P2 along the lipid bilayer.

207 g for receptor-specific signalling with free lateral diffusion of PIP(2).

208 st that the fast buildup prevents long-range lateral diffusion of polyelectrolyte star components, hi

209 how interactions between cellular pathways, lateral diffusion of proteins between synapses, and chlo

210 y forming diffusional barriers that restrict lateral diffusion of proteins embedded in membranes.

211 ) the influence of crowding and shape on the lateral diffusion of proteins in curved membranes; and 2

212 membrane (PM) for small molecules is low and lateral diffusion of proteins is slow.

213 Although it has been suggested that lateral diffusion of proteins on the membrane sets the r

214 permeability for small molecules and a slow lateral diffusion of proteins.

215 y generate pores of larger diameter enabling lateral diffusion of PS; whereas, smaller pores induced

216 Lateral diffusion of receptors occurs at both synaptic a

217 One such study, quantitative measurement of lateral diffusion of rhodopsin, set the standard for exp

218 854 Da, and were chosen to characterize the lateral diffusion of small compounds in these bilayer sy

219 les successful mapping of the transverse and lateral diffusion of small molecules having different ph

220 ncorporated into synapses during LTP is from lateral diffusion of spine surface receptors containing

221 This is a consequence of the fact that the lateral diffusion of stathmin tends to weaken the effect

222 This study shows that the lateral diffusion of sulforhodamine in human sclera is s

223 sis hypothesis and suggest the importance of lateral diffusion of surface proteins in contributing to

224 interphase by the mobile phase enhances the lateral diffusion of the amphiphile.

225 Major analytical aspects, such as lateral diffusion of the analyte molecules and differenc

226 ent sterols, revealed that the difference in lateral diffusion of the BODIPY-cholesterol probes was n

227 eously over the cytoplasmic membrane and the lateral diffusion of the channels is in accordance with

228 Extensive lateral diffusion of the chimeric proteins occurred betw

229 tions with members of the PSD-95 family, and lateral diffusion of the GluA1 receptors on the cell sur

230 Lateral diffusion of the lipid chelate results in Heisen

231 sition from gel-to-fluid phase increases the lateral diffusion of the lipid molecules by three orders

232 rall rotational diffusion of the vesicle and lateral diffusion of the lipid molecules, is responsible

233 tion and epifluorescence microscopy, and the lateral diffusion of the lipids and proteins in the bila

234 The nanoGFP-based probes allowed faster lateral diffusion of the NMDARs, with several-fold incre

235 ly decreased at 0 degrees C, suggesting that lateral diffusion of the permease within the plane of th

236 Membrane properties such as lateral diffusion of the SBMs on the silicate films are

237 ith the reduced order parameter and enhanced lateral diffusion of the substrate analogue in the prese

238 taneously measure temporal variations in the lateral diffusion of these proteins.

239 This implies that the lateral diffusion of thiolate ligands on the nanoparticl

240 ted reduction may reflect an increase in the lateral diffusion of transducin and an increased activat

241 The lateral diffusion of transmembrane proteins in cell memb

242 Clustering and lateral diffusion of ULBP1 was not affected by changes i

243 Lateral diffusion of unsaturated lipids was significantl

244 Thus there are fewer barriers to lateral diffusion on cytoskeleton mutant MEL cells than

245 diffusion and demonstrate how the effect of lateral diffusion on diffusion in the DBL can be account

246 with the fast remodeling plant ER, but their lateral diffusion on the ER surface was restricted, like

247 and transiently interacts with receptors via lateral diffusion on the plasma membrane.

248 but this difference does not strongly affect lateral diffusion on the scales measured here.

249 leaves the vicinity of the enzyme, either by lateral diffusion or desorption from the surface, regula

250 s with intracellular receptor pools, and the lateral diffusion or hopping of surface receptors betwee

251 the receptor either through plasma membrane lateral diffusion or through intracellular routes.

252 grana leads to protein crowding that impedes lateral diffusion processes but is required for efficien

253 ee, near-native environment with exceptional lateral diffusion properties.

254 predicted by the steric hindrance model, the lateral diffusion rate of band 3 is greater in spectrin-

255 Lateral diffusion rates of CP-55,940 and POPC were measu

256 maging and tracking has been used to measure lateral diffusion rates of fluorescent molecules at surf

257 Lateral diffusion rates were low when PPFD <300 micromol

258 ed two mechanisms for splice site pairing: a lateral diffusion ('scanning') model and the currently f

259 olesterol analogs have a severe influence on lateral diffusion specifically in the PM of living cells

260 junction protein occludin and increased the lateral diffusion speed of HCV receptor tetraspanin CD81

261 so observe a persistent decrease in Lyn-EGFP lateral diffusion that is dependent on Src family kinase

262 both dyes readily escape vesicle membrane by lateral diffusion through any exocytotic opening.

263 e in Pseudomonas putida F1 (PpF1) occurs via lateral diffusion through FadL channels.

264 This loss of polarity did not reflect lateral diffusion through junctional complexes because a

265 brane and then reaching the binding site via lateral diffusion through the lipid bilayer.

266 delivery exclusively to one pole followed by lateral diffusion through the outer membrane.

267 those in the cytoplasm, as evident from the lateral diffusion times t(D,free)(nuc) = t(D,free)(cyt)

268 oteins from the tissue sections with minimal lateral diffusion to achieve high spatial fidelity trans

269 ains with their associated molecules move by lateral diffusion to areas of cellular interactions to i

270 Loss of oxygen via lateral diffusion to the encapsulating Si3N4/SiO2 layer

271 results in AMPA receptor endocytosis and/or lateral diffusion to the extrasynaptic membrane.

272 d through axons and targeted to synapses via lateral diffusion together with syntaxin-1.

273 y (FPR) measurements of cell surface protein lateral diffusion typically employ an interrogated spot

274 entiated BMPC were found in clusters and the lateral diffusion was slow (e.g., approximately 10(-11)

275 The landscape of CD22 and its lateral diffusion were perturbed either in the absence o

276 on on the CB1 and CB2 receptors through fast lateral diffusion within the cell membrane.

277 gp appears to be rate-limited solely by drug lateral diffusion within the inner monolayer of the plas

278 usion across the sclera, this study examined lateral diffusion within the sclera parallel to the scle