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1 en's node can promote formation of IM in the lateral plate.
2 soderm that lies between the somites and the lateral plate.
3 ompartment comprising cells from somites and lateral plate.
4 ication has occurred in the node but not the lateral plate.
5 the prospective limb-forming regions of the lateral plate.
6 the prospective limb-forming regions of the lateral plate.
7 the prospective limb-forming regions of the lateral plate.
9 ced by GSK3-beta inhibition did not generate lateral plate and cardiac mesoderm and favored instead s
10 te nonmyogenic cells to the limb: stage 9-12 lateral plate and distal portions of stage 25/26 limbs.
12 metric gene expression at the node or in the lateral plate and exhibit right isomerism of the lungs.
13 a transcription factors are expressed in the lateral plate and in vasculogenic regions of the avian s
15 te mesoderm lies between the somites and the lateral plate and is the source of all kidney tissue in
16 eobox genes prx-1 and prx-2 are expressed in lateral plate and limb bud mesoderm, but targeted inacti
17 ed in conferring limb-forming ability to the lateral plate and may promote the initial outgrowth of l
19 t apparently adopt the Hox expression of the lateral plate and participate in the morphology appropri
24 ricted to the primitive streak and posterior lateral plate, and is absent from the anterior region wh
25 d the formation of all but the most anterior lateral plates, and another independently segregating fa
26 sis, ndr2 is expressed asymmetrically in the lateral plate as are nodal-related genes of other organi
28 esceinated dextran, confirms that, normally, lateral plate cells next to the notochord do not contrib
29 nt and explant experiments revealed that the lateral plate contains an activity that can repress IM f
32 First, the majority of the avian scapula is lateral plate derived and the somitic contribution to th
34 ns of somite-derived myogenic precursors and lateral plate-derived mesenchymal stroma to the establis
35 n the thoracic region, Hox genes pattern the lateral plate-derived sternum in a non-colinear manner,
36 e HSC lineage have been identified in dorsal lateral plate (DLP) mesoderm, and a transcriptional gene
38 ate embryo, the blood islands and the dorsal lateral plate (DLP), participate in early hematopoietic
40 g. neural tube, axial and paraxial mesoderm, lateral plate, ectoderm, endoderm) to drive axis morphog
41 ey strongly support the hypothesis that left lateral plate expression of nodal-related genes is a cau
44 anism for information relay between node and lateral plate in a process that is critical for the esta
45 asymmetric information from the node to the lateral plate is mediated by Caronte (Car), a novel memb
47 MP signaling no longer induces expression of lateral plate markers but now induces robust chondrogene
48 at additional cell types within the anterior lateral plate mesoderm (ALPM) also underwent subduction,
49 1 and Cyp26c1, are expressed in the anterior lateral plate mesoderm (ALPM) and predominantly overlap
50 ring primitive neutropoiesis in the anterior lateral plate mesoderm (ALPM) but has little effect on e
51 scripts are conspicuously absent in anterior lateral plate mesoderm (ALPM), where SHF progenitors are
54 sient asymmetric Nodal signaling in the left lateral plate mesoderm (L LPM) during tailbud/early somi
57 alities in asymmetric gene expression in the lateral plate mesoderm (LPM) and dorsal diencephalon of
58 is joined by dynamic expression in the left lateral plate mesoderm (LPM) and left dorsal endoderm.
59 mally is expressed predominantly in the left lateral plate mesoderm (LPM) and left side of the straig
60 elial to mesenchymal transition (EMT) in the lateral plate mesoderm (LPM) and myoblast migration into
61 l somatopleure, a tissue composed of somatic lateral plate mesoderm (LPM) and overlying ectoderm.
62 demonstrated loss of normal LR asymmetry in lateral plate mesoderm (LPM) antivin/lefty-1 and Pitx2 e
63 fish, asymmetric migration of the epithelial lateral plate mesoderm (LPM) displaces the gut leftward,
65 g in mouse embryonic stem cell (ESC)-derived lateral plate mesoderm (LPM) generates tracheal mesoderm
66 the primary heart field within the anterior lateral plate mesoderm (LPM) into a tubular heart involv
67 ulatory pathway specifically within the left lateral plate mesoderm (LPM) is critical for these event
68 os, the expression of Pitx2 gene in the left lateral plate mesoderm (LPM) is directly regulated by Xn
72 sion in the foregut endoderm and surrounding lateral plate mesoderm (lpm) prior to respiratory specif
73 These signals are then transferred to the lateral plate mesoderm (LPM) through cellular and molecu
74 the transmission of asymmetric cues from the lateral plate mesoderm (LPM) to the cardiac field but no
75 ide markers such as nodal bilaterally in the lateral plate mesoderm (LPM), indicating that loss of AC
76 restricted expression of Pitx2c in the left lateral plate mesoderm (LPM), left half of heart tube an
77 vements of the hepatic endoderm and adjacent lateral plate mesoderm (LPM), resulting in asymmetric po
78 es is thought to be derived exclusively from lateral plate mesoderm (LPM), which gives rise to a card
79 e node and Shh downstream genes in the right lateral plate mesoderm (LPM), while overexpression of ch
80 (hiPSCs) that were differentiated either to lateral plate mesoderm (LPM)-like cells, the development
92 n begins during the convergence of posterior lateral plate mesoderm (PLM), well before aorta formatio
93 le effect on erythropoiesis or the posterior lateral plate mesoderm (PLPM) expression of neutrophil m
95 velopment of two structures derived from the lateral plate mesoderm - the heart and the pectoral fin.
96 phological boundaries between somites and in lateral plate mesoderm a wing- or non-wing-forming bound
97 age tracing in the living embryo, are in the lateral plate mesoderm adjacent to the notochord-prechor
98 Subsequently, Nodal signaling from the left lateral plate mesoderm alleviates this repression ipsila
99 are good candidates for encoding position in lateral plate mesoderm along the body axis and thus for
101 ric midline domains and unilaterally in left lateral plate mesoderm and anterior dorsal endoderm.
102 localized to the presumptive presomitic and lateral plate mesoderm and CYP26 mRNA to the presumptive
103 eage perturbed asymmetric gene expression in lateral plate mesoderm and disrupted organ LR asymmetrie
104 to initiate molecular asymmetry in the left lateral plate mesoderm and exhibit multiple left-right p
105 regulates the developmental potential of the lateral plate mesoderm and is required cell autonomously
106 nitially specified in the dorsal part of the lateral plate mesoderm and later become incorporated int
107 riginate in distinct regions of the anterior lateral plate mesoderm and migrate to the midline where
109 to disrupt asymmetric gene expression in the lateral plate mesoderm and randomize the placement of in
110 tissues, a strong expression of RARbeta2 in lateral plate mesoderm and somites, and an anterior expr
111 ription factor expressed throughout the left lateral plate mesoderm and subsequently on the left side
112 known to be expressed asymmetrically in the lateral plate mesoderm and the brain during embryogenesi
113 The dermis originates from the somites, the lateral plate mesoderm and the cranial neural crest.
114 proliferation of hindlimb progenitors in the lateral plate mesoderm and the expression of a common fa
116 The gene Pitx2 is expressed in the left lateral plate mesoderm and, subsequently, in the left he
118 symmetric patterns of gene expression in the lateral plate mesoderm are initiated by signals located
121 by reciprocal transplantation of somites or lateral plate mesoderm at stages prior to muscle formati
122 rafish development, cbfb is expressed in the lateral plate mesoderm at tail bud stage and in the inte
124 xperiments show that bmp2a, expressed in the lateral plate mesoderm at these stages, is essential for
126 d with gata4 and nkx2.5 not only in anterior lateral plate mesoderm but also in noncardiac mesoderm a
127 ation, the cardiac progenitors reside in the lateral plate mesoderm but maintain close contact with t
128 ormed via repressing venous cell fate at the lateral plate mesoderm by Hh signaling during vasculogen
130 ls, are generally described to come from the lateral plate mesoderm despite experimental evidence for
131 ential expression timing of Hox genes in the lateral plate mesoderm determines limb placement as well
132 essed in restricted bilateral domains in the lateral plate mesoderm directly adjacent to the liver-fo
133 repression of Xnr-1 expression in the right lateral plate mesoderm during closure of the neural tube
134 mmetric and topological within the fin-field lateral plate mesoderm during early fin bud initiation.
135 maintain the expression of Pitx2 in the left lateral plate mesoderm during the patterning of left-rig
139 oderm for hindbrain patterning, and rarab in lateral plate mesoderm for specification of the pectoral
140 lly in the perinodal region of the posterior lateral plate mesoderm for the establishment of laterali
141 In these fish, GFP-expressing cells in the lateral plate mesoderm form two tubes that migrate ventr
142 tein) signaling activity specifically during lateral plate mesoderm formation while reducing fibrobla
143 re, we find the pericardium forms within the lateral plate mesoderm from dedicated mesothelial progen
144 of the fetal limb and axial skeleton, and in lateral plate mesoderm giving rise to visceral muscle.
145 developing node and at later stages in left lateral plate mesoderm has been implicated as a key regu
146 l is generated at the node and transduced to lateral plate mesoderm in a linear signal transduction c
147 oD, Myf-5, and myogenin in both paraxial and lateral plate mesoderm in the absence of inducing tissue
148 pressed in the intermediate mesoderm and the lateral plate mesoderm in the presumptive chick forelimb
149 Subsequent nodal and Pitx2 expression in the lateral plate mesoderm in these mice is randomized, indi
150 quivalent embryological origin: the anterior lateral plate mesoderm in vertebrates and the dorsal-mos
152 pendent regulation of Hox gene expression in lateral plate mesoderm may have been a key step in the e
155 verely downregulated or abolished within the lateral plate mesoderm of Southpaw-deficient embryos.
158 abel single or small patches of cells in the lateral plate mesoderm of the zebrafish and to track the
161 ntly in somites and unsegmented paraxial and lateral plate mesoderm overlapping atrial precursors in
162 Analysis of the cardiogenic potential of the lateral plate mesoderm posterior to nkx-2.5 and actR-IIa
163 ppropriate number of cardiomyocytes from the lateral plate mesoderm requires a careful balance of bot
164 r notochord in late neurulae, and finally in lateral plate mesoderm restricted to the left side of ta
165 s Islet1, a hindlimb-specific factor, in the lateral plate mesoderm results in a failure to induce hi
166 zyme in the gpi-biosynthetic pathway, in the lateral plate mesoderm results in normally patterned lim
167 ly identified, here we provide evidence that lateral plate mesoderm sends instructive signals to the
168 tion factor Hand2, which is expressed in the lateral plate mesoderm starting at the completion of gas
169 tion of zebrafish hrT expression in anterior lateral plate mesoderm suggest a very early role for hrT
170 tion as cardiac precursors converge from the lateral plate mesoderm territories toward the embryonic
171 ail2 function in a regulatory circuit within lateral plate mesoderm that directs normal vessel format
172 on of the expression domain corresponding to lateral plate mesoderm that is part of the early heart f
174 red during somitogenesis within the anterior lateral plate mesoderm to induce myocardial differentiat
175 ine the relative contribution of somitic and lateral plate mesoderm to the avian scapula from quail-c
176 nt development, angioblasts migrate from the lateral plate mesoderm to the midline where they form a
177 regulation of the cell fate transition from lateral plate mesoderm to the specification of cardiomyo
178 ogenitor cells (HPCs) move from the anterior lateral plate mesoderm to the ventral midline, undergoin
179 that these cells migrate from the posterior lateral plate mesoderm to their site of differentiation
180 uilding on established methods, hPSC-derived lateral plate mesoderm treated with either retinoic acid
181 rmerly lefty-2), nodal and Pitx2 in the left lateral plate mesoderm was absent, suggesting that Gdf1
182 onephros induction, stage 7 or earlier chick lateral plate mesoderm was cocultured with caudal stage
183 ymmetric Nodal signaling cascade in the left lateral plate mesoderm was detected, and began to be unr
184 Snrk-1 control angioblast populations in the lateral plate mesoderm with Dusp-5 functioning downstrea
185 steps of this cascade (before it reaches the lateral plate mesoderm) results in random left-right asy
186 d shift of Nodal expression in the left LPM (lateral plate mesoderm), and speculate that the higher l
187 vascular zones are directly generated by the lateral plate mesoderm, a critical source of Sema3E.
188 ective angioblast migration in the posterior lateral plate mesoderm, a process known to depend on vas
189 rated and propagated from the KV to the left lateral plate mesoderm, activating a transcriptional res
190 skeleton and sternum arise from the somatic lateral plate mesoderm, and all of the muscles for both
191 The second population resides in the dorsal lateral plate mesoderm, and contains precursors of adult
192 tion to the neural groove, primitive streak, lateral plate mesoderm, and Hensen's node, while distinc
193 he nodal-related gene southpaw (spaw) in the lateral plate mesoderm, and its downstream targets pitx2
194 e of the genes specifically expressed in the lateral plate mesoderm, and later in its derivative, the
197 superfamily, which is expressed in the left lateral plate mesoderm, and loss of nodal function produ
198 entral neural tube, notochord, ectoderm, and lateral plate mesoderm, and none was detected in the neu
199 soderm, the primitive streak at the level of lateral plate mesoderm, and the base of the allantois.
200 These somites induced ectopic pronephroi in lateral plate mesoderm, and the IM that received signals
201 llinear domains of expression in the forming lateral plate mesoderm, as demonstrated by functional pe
203 silon is an adapter protein expressed in the lateral plate mesoderm, but its in vivo cardiac function
204 of Xc-Myc, XSlug/Snail2 or XTwist within the lateral plate mesoderm, but not the neural crest, provok
205 onveyed to the node, and subsequently to the lateral plate mesoderm, by a complex cascade of epigenet
206 mesenchyme with cranial mesenchyme, but not lateral plate mesoderm, could rescue expression of the R
207 tive signals emanating from the neighbouring lateral plate mesoderm, directing the endoderm towards s
210 first heart field differentiates earlier in lateral plate mesoderm, generates the linear heart tube
211 s show the requirement for Prt/Wnt2bb in the lateral plate mesoderm, in agreement with the inductive
213 embryos, tmem88a is expressed broadly in the lateral plate mesoderm, including the bilateral heart fi
214 absent, nodal signaling is randomized in the lateral plate mesoderm, leading to aberrant LR orientati
215 The chicken Tbx gene, Tbx18, is expressed in lateral plate mesoderm, limb, and developing somites.
216 is study, cux2, is expressed in the pre-limb lateral plate mesoderm, posterior limb bud and flank mes
217 n by altering the patterning of the anterior lateral plate mesoderm, potentially favoring formation o
218 1 disrupts asymmetric gene expression in the lateral plate mesoderm, resulting in aberrant looping of
219 that are normally expressed only in the left lateral plate mesoderm, show expression in the right and
220 n analyses show that Bmp2b, expressed in the lateral plate mesoderm, signals through Alk8 to induce e
222 tissues, as well as the surface ectoderm and lateral plate mesoderm, together act to pattern somitic
223 ne expression domains are established in the lateral plate mesoderm, ultimately determining the direc
224 odel with conditional deletion of WT1 in the lateral plate mesoderm, using the G2 enhancer of the Gat
225 m, and for the absence of Flk-1, a marker of lateral plate mesoderm, we derive a cell population from
226 different rostral and caudal domains of the lateral plate mesoderm, where limb induction occurs, mig
227 get genes Pitx2c, Nodal and Ebaf in the left lateral plate mesoderm, where they are required for esta
230 de dehydrogenase-2 (Raldh2) expressed in the lateral plate mesoderm, which generates a proximodistal
231 ular matrix degradation by SMCs derived from lateral plate mesoderm, which was confirmed using rat ao
232 Zebrafish gastrulae express agtrl1b in the lateral plate mesoderm, while apelin expression is confi
233 ty2/antivin, and Pitx2 does not occur in the lateral plate mesoderm, while in Cryptic mutants Lefty1
234 tissues from two different germ layers; the lateral plate mesoderm-derived mesenchyme and ectoderm-d
235 mutant, the position of the hindlimb bud, a lateral plate mesoderm-derived structure, is posteriorly
236 es containing cells of all five of the major lateral plate mesoderm-derived tissues (cartilage, peric
280 ess through the primitive streak and to form lateral plate mesoderm; and prospective mesoderm from on
281 Ectopic expression of Pitx2 in the right lateral-plate mesoderm alters looping of the heart and g
282 Expression reappears transiently in the left lateral-plate mesoderm, and in an unprecedented asymmetr
283 itx2 is asymmetrically expressed in the left lateral-plate mesoderm, and mutant mice with laterality
284 me), head paraxial mesoderm or non-paraxial (lateral plate) mesoderm tested in this assay were each a
285 ad us to propose that Tbx5a confers anterior lateral plate mesodermal cells the competence to respond
287 ly the early mesodermal marker Brachy-T, the lateral plate mesodermal marker FLK1, and the endothelia
288 involve the directed migration of individual lateral-plate mesodermal cells into the future limb-bud-
290 b-forming ability by discrete regions of the lateral plate of the chick embryo is dependent on a medi
291 b-forming ability by discrete regions of the lateral plate of the chick embryo is thought to depend o
293 f the strong association between stickleback lateral plate phenotypes and Ectodysplasin A (Eda) genot
294 on of the cryptic border between somitic and lateral plate populations reveals the dynamics of muscul
296 metrically in the left diencephalon and left lateral plate respectively, suggesting an additional rol
297 lance between Nodal and BMP signaling in the lateral plate that is critical for L/R axis formation.
298 the somites followed by lower levels in the lateral plate; the posterior half of the limb bud genera
299 , the node, and involves signal relay to the lateral plate, where it results in asymmetric organ morp
300 h as stage 9-15 neural tubes and stage 9- 12 lateral plates, while these transcripts are found at ver