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1 tors include members of the NKRP1 and C-type lectin-like 2 (CLEC2) gene families, which constitute ge
2 planin and collagen/fibrin receptors, C-type-lectin-like-2 (CLEC-2) and glycoprotein VI (GPVI), respe
6 a preferential expansion of licensed, C-type lectin-like activating receptor Ly49H+ NK cells with inc
8 ly, bacteria that lacked PRP-binding and the lectin-like activities detected by binding to MG2 failed
12 ta-glucans but not by mannans, implicating a lectin-like activity in recognition but distinct in spec
14 These findings uncover the importance of the lectin-like activity of the polymeric FimA shaft rather
15 er, by using Escherichia coli expressing the lectin-like adhesin FimH and guinea pig erythrocytes in
16 coaggregation of streptococci occurs when a lectin-like adhesin on one streptococcal species recogni
17 mensal S. oralis functions as a receptor for lectin-like adhesins on other members of the dental plaq
18 oralis and related species are recognized by lectin-like adhesins on other members of the oral biofil
19 tions are frequently based on the binding of lectin-like adhesins to specific glycan determinants exp
23 roperties of alpha- and theta-defensins, the lectin-like behavior of defensins may contribute to many
28 FcepsilonRI subunits, associates with the ER lectin-like chaperone calnexin, but not the structurally
31 For example, calreticulin, a quality-control lectin-like chaperone, interacts with glucosylated manno
32 ribonuclease (RNase) as specific ligands of lectin-like chaperones calnexin (CNX) and calreticulin (
36 al amino acid residues located in the C-type lectin-like domain (CTLD) and the sperm-coating protein/
38 rystal structure of the extracellular C-type lectin-like domain (CTLD) of human CD69 at 2.27 A resolu
40 ent receptor 3 (CR3) (CD11b/CD18) contains a lectin-like domain (LLD) that can alter leukocyte functi
41 uble yeast beta-glucan, a ligand for the CR3 lectin-like domain (LLD), in the priming of CR3(+) HPC i
42 e comprising the human tumor necrosis factor lectin-like domain (TIP domain) sequence, is currently b
43 fibronectin-like type II (FnII), and C-type lectin-like domain 1 (CTLD1) domains of PLA2R only under
44 reviously, we showed that the recombinant TM lectin-like domain binds to LPS and inhibits LPS-induced
45 xpression of a mutant form of TM lacking the lectin-like domain had no significant impact on metastas
47 domain 1 (TMD1) to demonstrate the action of lectin-like domain in blocking Lewis Y antigen (LeY)-med
48 investigated the role of the thrombomodulin lectin-like domain in the host response to Gram-negative
49 me a detrimental role for the thrombomodulin lectin-like domain in the host response to sepsis caused
51 we solved a crystal structure of the C-type lectin-like domain of a homologous protein, NKR-P1A, usi
52 inant C1qRp-Fc chimera containing the C-type lectin-like domain of C1qRp and found specific binding t
53 rystal structure of the extracellular C-type lectin-like domain of human Lox-1 reveals a heart-shaped
55 terpret the solution structure of the C-type lectin-like domain of NKR-P1C using chemical cross-linki
59 not differ between groups, mice lacking the lectin-like domain of thrombomodulin displayed strongly
60 ue of Blood, Kuo et al have used recombinant lectin-like domain of thrombomodulin domain 1 (TMD1) to
62 xposure to B. pseudomallei, mice lacking the lectin-like domain of thrombomodulin showed a survival a
64 type mice (TM(wt/wt)) and mice that lack the lectin-like domain of TM (TM(LeD/LeD)), which is critica
66 be formation and the role of the recombinant lectin-like domain of TM-TM domain 1 (rTMD1)-in antiangi
67 assessed the physiological relevance of the lectin-like domain of TNF in alveolar liquid clearance i
68 on and indicate a physiological role for the lectin-like domain of TNF in the resolution of alveolar
71 nism by which the TIP peptide, mimicking the lectin-like domain of tumor necrosis factor (TNF), stimu
72 eins, with each subunit composed of a C-type lectin-like domain tethered to the membrane by a stalk r
73 ), is unique among integrins in containing a lectin-like domain that binds the fungal pathogen-associ
74 ombin-mediated proteolysis and an N-terminal lectin-like domain that controls inflammatory processes.
75 dditional antiparallel beta-sheet carrying a lectin-like domain that could be responsible for EPS bin
76 RCMV) encodes a 20-kDa protein with a C-type lectin-like domain that is expressed in the delayed-earl
77 cytes and other cells, contains a C-terminal lectin-like domain that resembles C-type carbohydrate-re
82 I domains were folded back to contact C-type lectin-like domains 1-6, and a "tail" comprising C-type
88 nts, and glycan array analysis employing the lectin-like domains of cow and mouse CD23 demonstrate th
89 s the possibility that a protein with C-type lectin-like domains regulated development in the last co
90 tein with predicted transmembrane and C-type lectin-like domains, regulates UNC-40-mediated axon outg
91 comprising two intercalated rings of C-type lectin-like domains, where the N-terminal cysteine-rich
93 t from the cytolysin domain, VCC harbors two lectin-like domains: the beta-Trefoil and the beta-Prism
96 bin-independent, constitutive manner via its lectin-like extracellular domain; and inhibits the infla
97 cRLKs) are members of RLK family composed of lectin-like extracellular recognition domain, transmembr
99 structure reveals conservation of the C-type lectin-like fold, including preservation of the two alph
100 Our study shows that most EpaA domains exert lectin-like functions and together recognize a wide vari
101 onstrated that the core promoter of the RCMV lectin-like gene contains a GATA rather than a TATA box.
103 termined the crystal structures of the human lectin-like head domain of CD23 in its Ca(2+)-free and C
104 solved the crystal structure of the soluble lectin-like "head" domain of CD23 (derCD23) bound to a s
109 this association does not require the known lectin-like interaction between L-selectin and PSGL-1, t
111 1, NKRP1A, NKp80, NKp65) instead bind C-type lectin-like ligands to which they are genetically linked
112 I to including related NK cell receptors for lectin-like ligands, and reflect genetic strategies for
113 lanking the N and C termini of the consensus lectin-like Link module, bridged by a third conserved di
114 e DCAL-1 locus is within a cluster of C-type lectin-like loci on human chromosome 12p12-13 just 3' to
116 inhibitory receptors belonging to the C-type lectin-like (Ly-49, CD94/NKG2) and Ig superfamily-relate
119 el whereby at low calcium concentrations the lectin-like module drops away from EGF3 concomitant with
120 PEC to induce A/E lesions requires an intact lectin-like module residing at the carboxy-terminus of t
121 odule with 13 calcium-binding repeats, and a lectin-like module) binds 30 calcium ions and forms exte
125 upport the idea that the EGF-like, wire, and lectin-like modules constitute a dynamic and interactive
127 ability of interactions between the wire and lectin-like modules, stabilities of the EGF-like and wir
131 first characterization of the orphan C-type lectin-like molecule Clr-a encoded by the Clec2e gene in
134 dant function of these highly related C-type lectin-like molecules in the context of intestinal immun
135 nvolves NK gene complex (NKC)-encoded C-type lectin-like molecules such as NKG2D and Nkrp1 receptors.
137 by structural studies to bind to the C type-lectin-like natural killer receptor, providing insight i
139 iller (NK) gene complex (NKC) encodes orphan lectin-like NK cell receptors that may explain uncharact
141 dopts a fold similar to that of other C-type lectin-like NK receptors, including Ly49A, NKG2D and CD6
143 tory of the NKC, we characterized the C-type lectin-like NKC genes and their organization from four m
145 scavenger receptor class A, types I and II, lectin-like ox-LDL receptor-1, macrophage receptor with
149 ivity of the multi-ligand scavenger receptor Lectin-like Oxidized LDL Receptor-1 (LOX-1) is associate
150 ptosis in cultured endothelial cells through lectin-like oxidized LDL receptor-1 (LOX-1) signaling, a
151 hown to activate platelets via its receptor, lectin-like oxidized LDL receptor-1 (LOX-1), and alphabe
152 ed the association of 3 polymorphisms in the lectin-like oxidized LDL receptor-1 (LOX1 or OLR1) gene
153 ough platelet-activating factor receptor and lectin-like oxidized LDL receptor-1 to attenuate Akt act
154 receptors, including TLR9, pentraxin-3, and lectin-like oxidized LDL receptor-1, was regulated, in p
155 cted when the entire intracellular domain of lectin-like oxidized low density lipoprotein receptor 1
156 ndicate that three members of the SR family (lectin-like oxidized low density lipoprotein receptor 1;
159 CD68, scavenger receptor (SR)-A, SR-BII, and lectin-like oxidized low-density lipoprotein receptor (L
160 acrophage scavenger receptor type AI/AII and lectin-like oxidized low-density lipoprotein receptor-1
162 The gene expression of CD36, SR-BII, and lectin-like oxidized low-density lipoprotein receptor-1
165 he MSR genes CD36 and CD68, SR-A and SR-BII, lectin-like oxidized low-density lipoprotein receptor-1,
166 l of this study was to determine the role of lectin-like oxidized low-density lipoprotein receptors (
168 antigens to human DCs via DC-ASGPR, but not lectin-like oxidized-LDL receptor, Dectin-1, or DC-speci
169 ive stress via interaction with the receptor lectin-like oxLDL receptor (LOX)-1 and subsequent NAD(P)
170 Rho kinase inhibition and the absence of the lectin-like OxLDL receptor-1 in knockout mice also ablat
171 ors of mitochondrial processing peptidase or lectin-like OxLDL receptor-1 knockout attenuated OxLDL-m
172 t the 14-kDa protein of B. abortus possesses lectin-like properties and is essential for the virulenc
173 l, cysteine-rich antimicrobial peptides with lectin-like properties exist in plants, theta-defensins
176 nes, a newly identified four-exon gene for a lectin-like protein (in rat cytomegalovirus), and 10 pro
178 e show that a complex encompassing the yeast lectin-like protein Htm1 and the oxidoreductase Pdi1 con
180 teomic analyses of mucus have identified the lectin-like protein ZG16 (zymogen granulae protein 16) a
181 r histocompatibility complex class I, C-type lectin-like protein, and transforming growth factor beta
184 d aspartyl protease, and another AED, LEGUME LECTIN-LIKE PROTEIN1 (LLP1), were induced locally and sy
186 pled receptors glycoprotein (GP)VI or C-type lectin-like receptor (CLEC)-2 is associated with only a
187 or platelet-specific deletion of the C-type-lectin-like receptor (CLEC-2) exhibit hemorrhaging in th
193 e development, binding of Pdpn to the C-type lectin-like receptor 2 (CLEC-2) on platelets is critical
195 m are a platelet activation receptor, C-type lectin-like receptor 2 (CLEC-2), and its endogenous liga
196 ein VI (GPVI)-FcR gamma-chain and the C-type lectin-like receptor 2 (CLEC-2), respectively, support c
197 lycoprotein (GP)VI-FcRgamma chain and C-type lectin-like receptor 2 (CLEC-2)-mediated platelet activa
200 as an activating ligand for platelet C-type lectin-like receptor 2 (CLEC-2, also known as CLEC1B).
201 ein VI (GPVI) and podoplanin receptor C-type lectin-like receptor 2 (CLEC2) are receptors implicated
202 nt for the platelet-specific receptor C-type lectin-like receptor 2 (CLEC2) as blood backfills the ly
205 specifically inhibited collagen- and C-type lectin-like receptor 2-induced human platelet aggregatio
206 e and essential role in collagen- and C-type lectin-like receptor 2-mediated platelet activation and
209 CD141(+) DC in humanized mice express C-type lectin-like receptor 9A, XCR1, CADM1, and TLR3 but lack
211 example, increased expression of killer cell lectin-like receptor B1 (KLRB1; CD161) 28 days postvacci
214 cal MHC-I-peptide (pMHC-I) complexes and the lectin-like receptor CD94-NKG2A by nonclassical pMHC-I c
216 increased expression of SIGLEC-1 (CD169), a lectin-like receptor expressed on CD14(+) monocytes.
219 rance of short-lived (CD127(low) killer cell lectin-like receptor G 1-high) and memory-precursor (CD1
222 iferation coupled with decreased killer cell lectin-like receptor G-1 up-regulation on responding CD8
223 fied by reciprocal expression of killer cell lectin-like receptor G1 (KLRG1) and CD127, have differen
226 rogrammed death-1 (PD-1) and the killer cell lectin-like receptor G1 (KLRG1) delineated subpopulation
227 he T cell differentiation marker killer cell lectin-like receptor G1 (KLRG1) during M. tuberculosis i
229 We determined the structure of killer cell lectin-like receptor G1 (KLRG1) in complex with E-cadher
230 igh expression of the inhibitory killer cell lectin-like receptor G1 (KLRG1) in individuals >70 y.
233 robust terminally differentiated killer cell lectin-like receptor G1 (KLRG1)(hi) effector population,
234 ha expression did not rescue the killer cell lectin-like receptor G1 (KLRG1)(hi) short-lived effector
235 ng CD8 T cell subsets expressing killer cell lectin-like receptor G1 (KLRG1)(high) or KLRG1(low) had
236 s virus infection, we found most killer cell lectin-like receptor G1 (KLRG1)(lo)IL-7R(hi) effector an
237 CD8+ T cells expressing CD57 and killer cell lectin-like receptor G1 (KLRG1), which was negatively as
243 kin-7 receptor and low levels of killer cell lectin-like receptor G1 [IL-7Rhi KLRG1lo]) and had highe
244 ers of terminal differentiation, killer cell lectin-like receptor G1 and CD57, were expressed at lowe
246 This led to generation of CD8(+)/killer cell lectin-like receptor G1 high (KLRG1(hi))/IL-7R(lo) short
247 educed numbers of ADAP-deficient killer cell lectin-like receptor G1(-) CD8 resident memory T (TRM) c
248 tus, including CXCR3, CD127, and killer cell lectin-like receptor G1, and are superior to CD62L in pr
249 R-alpha, decreased expression of killer cell lectin-like receptor G1, and enhanced persistence of the
250 n of a population that expresses killer cell lectin-like receptor G1, and the majority of the resulti
251 Analysis of transcripts for killer cell lectin-like receptor G1, IL-7R, and CD57 implied that lu
255 The activation of platelet receptor C-type lectin-like receptor II-type (CLEC-2) could partially me
256 ived effector cells (SLECs) that express the lectin-like receptor KLRG-1, but how it operates remains
257 tically significant reduction in killer cell lectin-like receptor mRNA expression between cultures wi
262 integration of Toll-like receptor and C-type lectin-like receptor signaling mechanisms culminating in
264 this study, we demonstrate that killer cell lectin-like receptor subfamily G member 1 (KLRG1), a tra
265 ction of an inhibitory receptor, killer cell lectin-like receptor subfamily G member 1 (KLRG1), in th
267 tiation including an increase in killer cell lectin-like receptor subfamily G member 1 and shorter te
268 cells expressing high levels of killer cell lectin-like receptor subfamily G, member 1 (KLRG1), and
270 discovered platelet receptor CLEC-2 (C-type lectin-like receptor) perpetuates and worsens liver dama
272 usly described the cloning of a novel C-type lectin-like receptor, KLRH1, encoded in the NK complex a
273 accumulation of ox-LDL and expression of its lectin-like receptor, LOX-1, have been shown in atherosc
274 xidatively modified LDL (ox-LDL) activates a lectin-like receptor, LOX-1, which results in the expres
276 mbosis within vessels via ligation of C-type lectin-like receptor-2 (CLEC-2) on platelets by podoplan
277 owing receptors: glycoprotein (GP)VI, C-type lectin-like receptor-2 (CLEC-2)>GPIb>alpha6beta1, alphaI
279 ergic beta-2 receptor (ADRB2), oxidized LDL (lectin-like) receptor 1 (OLR1), and IL-8 receptor-alpha
281 in-like receptors (KIRs) and the killer cell lectin-like receptors (KLRs), and attempt to trace their
284 G1) is one of several inhibitory killer cell lectin-like receptors expressed by NK cells and T lympho
285 gene complex-encoded immunomodulatory C-type lectin-like receptors include members of the NKRP1 and C
286 cells in mice detect cells in distress using lectin-like receptors that bind to self-MHC class I mole
287 ) gene complex (NKC) encodes numerous C-type lectin-like receptors that govern the activity of NK cel
288 The asialoglycoprotein receptor or other lectin-like receptors were not detected on the apical su
289 ogen recognition receptors, including C-type lectin-like receptors, TLRs, and nucleotide oligomerizat
290 mplex (NKC) encodes a large number of C-type lectin-like receptors, which are expressed on NK and oth
292 he Sam n1 allergen fit best with a monomeric lectin like SELlm (Mr 34.2 kDa) found in shoots of dwarf
293 lergen could be a sequence-related monomeric lectin like SELlm present in shoots of Sambucus ebulus r
295 l streptococci function as receptors for the lectin-like surface adhesins on other members of the ora
296 udy was to reveal a possible role of NKR-P1A/lectin-like transcript 1 (LLT1) interaction in NK cell-m