ライフサイエンスコーパス: leopard

1 cies (lion, tiger, leopard, jaguar, and snow leopard).

2 home range sizes by 35% (wild dogs) to 66% (leopards).

3 at species, including the widely distributed leopard.

4 o generate hypotheses about the functions of leopard.

5 specialization appeared to disadvantage male leopards.

6 tance, and lower heterozygosity than African leopards.

7 rn Southern African cheetahs than in African leopards.

8 nant of the lifetime reproductive success in leopards.

9 We sequenced 53 whole genomes of African leopards.

10 s were more complex in the tiger than in the leopards.

11 nowledge is particularly scarce for the snow leopard, a conservation flagship species of Central Asia

12 For leopards, a subordinate carnivore, the top-down pressure

13 broadly monophyletic with respect to African leopards across almost their entire nuclear genomes.

14 Snow leopard activity was in contrast to their prey, which we

15 Female leopards also cared for sons longer than daughters, in l

16 Here, we introduce LEOPARD, an innovative approach specifically designed to

17 at is on average 3 times that inflicted by a leopard and 100 times that from a wolf.

18 s (additionally recorded in South Africa) in leopard and aggressive contexts.

19 ypical pyramidal neurons between the African leopard and cheetah.

20 ridization between the ancestors of the snow leopard and lion lineages.

21 e mutations in SHP2 cause clinically similar LEOPARD and Noonan syndromes, two of several autosomal-d

22 After the extirpation of leopards and African wild dogs from Mozambique's Gorongo

23 predators are threatened globally including leopards and cheetahs, both listed as 'vulnerable' by IU

24 ing to compare selected TLR genes in African leopards and cheetahs.

25 f interest: diet (grasses and fish), danger (leopards and crocodiles), social organization (troops an

26 nced the diet, space use and reproduction of leopards and lions in South Africa's Sabi Sands Game Res

27 rpreting communication behaviours of clouded leopards and other solitary felids.

28 areas, which accommodated a high density of leopards and provided refugia in a landscape with substa

29 ion incident was greater for wolves than for leopards and that surplus predations by both species occ

30 nt antelope (impala) and its main predators (leopards and wild dogs) with a series of manipulative fi

31 the related developmental disorders Noonan, LEOPARD, and cardiofaciocutaneous syndromes.

32 h two state-of-the-art methods, Catchitt and Leopard, and show that our method outperforms previous m

33 exposure to chronic long-term risk from snow leopards, and argali for wolves, in a nearly symmetrical

34 s in Indonesian Borneo are novel for clouded leopards, and contrary to previous descriptions of their

35 ding tigers, cheetahs, leopards, lions, snow leopards, and jaguars, are protected under the Conventio

36 viour primarily appears to be a strategy for leopards, and possibly other short-term cachers, to redu

37 This sets the leopard apart from most other widely distributed large A

38 jeopardising their own survivorship, female leopards apparently "hedge their bets" with current offs

39 wever, all previous whole-genome analyses of leopards are based on the Far Eastern Amur leopards that

40 We find that Asian leopards are broadly monophyletic with respect to Africa

41 Leopards are the only big cats still widely distributed

42 ng in fewer losses of livestock, wolves, and leopards, as these two carnivore species are mainly kill

43 n lions and subordinate felids (cheetahs and leopards) by up to 119%, but only lion-cheetah encounter

44 motivating example, we use two years of snow leopard camera trapping data from the same areas in the

45 he close genetic relationship with the Asian leopard cat (Prionailurus bengalensis), and identify 7.4

46 en the domestic cat (F. catus) and the Asian leopard cat (Prionailurus bengalensis).

47 The mean proportion of leopard cat DNA in the Bengal breed is 3.48%, lower than

48 nin intensity, are explained by selection of leopard cat genes whose expression is reduced in a domes

49 ir genome from domestic cats, regions of the leopard cat genome are thought to account for the unique

50 s, (4) puma group, (5) Lynx genus, (6) Asian leopard cat group, (7) caracal group, and (8) bay cat gr

51 -C contact map from an F1 domestic cat/Asian leopard cat hybrid and demonstrated the formation of the

52 Overall, leopard cat introgressions do not show strong signatures

53 pecies, including the golden monitor lizard, leopard cat, and four-horned antelope, were among the re

54 eveloped from intercrosses between the Asian leopard cat, Prionailurus bengalensis, and the domestic

55 igree between the domestic cat and the Asian leopard cat, this map was generated entirely with domest

56 as a species-specific strain of FIV, and the leopard cat, which has a domestic cat FIV strain in one

57 N1 avian influenza virus was found in a wild leopard cat.

58 at are associated with domestic, rather than leopard, cat haplotypes.

59 etween jungle cats (p = 0.500 +/- 0.289) and leopard cats (p = 0.501 +/- 0.288); however, occupancy (

60 verlap between jungle cats (Felis chaus) and leopard cats (Prionailurus bengalensis).

61 for jungle cats (psi = 0.247 +/- 0.020) than leopard cats (psi = 0.178 +/- 0.019).

62 n cats and male jungle cats, female mainland leopard cats and female domestic cats, and female marble

63 We observed high diel overlap between leopard cats and jungle cats (Dhat1 = 0.802, norm0CI: 0.

64 and temporal overlap of sympatric jungle and leopard cats are influenced by habitat preferences, and

65 Co-existence of jungle cats and leopard cats in PKC appears to be facilitated by spatial

66 Jungle cats and leopard cats were positively associated with large preda

67 e the largest, whilst the mainland and Sunda leopard cats were the smallest.

68 olden cats, female jungle cats, female Sunda leopard cats, and male marbled cats were well differenti

69 nd interactions between sympatric jungle and leopard cats.

70 include the large African carnivores (lion, leopard, cheetah, and spotted hyena), where FIV is widel

71 ow population differentiation within African leopards compared with those of other big cats.

72 During the dry season, when risk of human-leopard conflicts is highest, leopards selected tea plan

73 distinctions increase the urgency of clouded leopard conservation efforts, and if affirmed by morphol

74 y presence drives leopard distribution, that leopard density exhibits a negative response to tiger oc

75 ah were generally larger than in the African leopard, despite similar brain sizes.

76 The number of leopards detected in Tandoureh National Park (30 individ

77 und evidence of individual specialization in leopard diet, with respect to both the species and size

78 We found that clouded leopards displayed 10 distinct communication behaviours,

79 We found that prey presence drives leopard distribution, that leopard density exhibits a ne

80 urons in the cheetah which, unlike lions and leopards, does not belong to the Panthera genus, suggest

81 Alarm calls given in response to leopards, eagles, and snakes could be well distinguished

82 a many-to-many neural network architecture, Leopard features a hundredfold to thousandfold speedup c

83 e we present a novel deep learning approach, Leopard, for predicting TF binding sites at single-nucle

84 e/absence data of seven species (golden cat, leopard, forest elephant, forest buffalo, western gorill

85 ecture of the dorsal nucleus of the Northern leopard frog (Rana pipiens pipiens), which is a homolog

86 f the forebrain and midbrain in the northern leopard frog (Rana pipiens) and common American toad (Bu

87 11/N20/R103-variant, oocytes of the Northern Leopard frog (Rana pipiens) contain another homologue of

88 We exposed Northern leopard frog (Rana pipiens) larvae through metamorphosis

89 y animal model for M. marinum disease in the leopard frog (Rana pipiens), a natural host species.

90 cells within the reticular formation of the leopard frog have an organization similar to that found

91 The leopard frog optic tectum is the principal target of the

92 rasitic flatworms) in the declining northern leopard frog Rana pipiens.

93 aspecific geographic variation in widespread leopard frog species has resulted in considerable taxono

94 prey foraging trials, predation of palatable leopard frog tadpoles was limited by prey availability a

95 (spotted frog), Rana berlandieri (Rio Grande leopard frog) and Rana pipiens (Northern leopard frog).

96 nde leopard frog) and Rana pipiens (Northern leopard frog).

97 zed range-wide MHC diversity in the Northern leopard frog, Rana pipiens, a species found throughout N

98 ferent synapse of saccular hair cells of the leopard frog, Rana pipiens.

99 l nerve were identified and described in the leopard frog, Rana pipiens.

100 are present in the hypoglossal nerve of the leopard frog, Rana pipiens.

101 velopment of its serotonergic neurons in the leopard frog.

102 frogs, American toads (Anaxyrus americanus), leopard frogs (Lithobates pipiens) and spring peepers (P

103 s crucifer), Pacific treefrogs (P. regilla), leopard frogs (Lithobates pipiens), and Cascades frogs (

104 urse of a year, five populations of Southern leopard frogs (Rana [Lithobates] sphenocephala) in Tenne

105 analysis of EphA and ephrin-A expression in leopard frogs (Rana pipiens and utricularia), species ca

106 l granulomatous infection in immunocompetent leopard frogs (Rana pipiens).

107 group of frogs (the Rana pipiens complex, or leopard frogs) that are widely distributed across Mexico

108 avior, we raised larval amphibians (northern leopard frogs, Lithobates pipiens) in 0, 1, or 10 mug/L

109 is of novel antimicrobial peptide genes from leopard frogs, Rana.

110 nd during chronic granulomatous infection of leopard frogs, suggesting that Erp function is similarly

111 superficial tectal locations in a series of leopard frogs.

112 sing data from 2032 prey items killed by 104 leopards from 2013 to 2015, we built generalized linear

113 As for many lizards, the leopard gecko (Eublepharis macularius) can self-detach i

114 evelopmental noise, can be distinguished for leopard gecko (Eublepharis macularius) head color patter

115 are likely to control such behaviors in the leopard gecko and also are candidate neural substrates f

116 ss this question, we identified areas of the leopard gecko brain that express androgen receptor (AR)

117 on the development of the banded pattern of leopard gecko hatchlings and the transition to black spo

118 The leopard gecko is a lizard lacking sex chromosomes, depen

119 ic development determines gonadal sex in the leopard gecko, Eublepharis macularius.

120 Host species included Gila monster, leopard gecko, fat-tail gecko, blue-tongued skink, Tokay

121 The leopard gecko, like many oviparous reptiles, lacks sex c

122 Leopard geckos (Eublepharis macularius) possess a large

123 In male leopard geckos (Eublepharis macularius), the incubation

124 otype in a 13-generation pedigree of captive leopard geckos, Eublepharis macularius, a TSD reptile.

125 in color pattern seen on the heads of eight leopard geckos.

126 the dorsal skin of the Mack Super Snow (MSS) leopard geckos.

127 ty highlighted the cryptic structure of snow leopard genetic diversity, likely driven by its ability

128 We generated a new high-quality leopard genome assembly, as well as two wild Amur leopar

129 lts bring molecular understanding to how the leopard got its spots, suggest that similar mechanisms u

130 Golden cat and leopard had the lowest occurrence rates in the region, w

131 This suggests leopards have the potential to navigate mixed mosaic lan

132 n that likely affect reproduction of clouded leopards, highlighting the urgent need for effective con

133 airoviruses, and are hereafter designated as Leopards Hill virus (LPHV).

134 Leopards hoisted 51% of kills.

135 dae (domestic cat, tiger, lion, cheetah, and leopard), Hominidae, and Bovidae genomes.

136 and broadcast large carnivore vocalizations (leopard, hyena, dog) or non-threatening control vocaliza

137 umans than lions (significantly in giraffes, leopards, hyenas, zebras, kudu, warthog, and impala) or

138 LEOPARD-imputed data also achieve the highest agreement

139 the factors motivating such behaviour among leopards in the Sabi Sand Game Reserve, South Africa, as

140 sociated with the length of maternal care in leopards in the Sabi Sand Game Reserve, South Africa.

141 he scent marking behaviours of Sunda clouded leopards in the wild.

142 nd that the genomic diversity in the African leopard is 2- to 5-fold higher than in other big cats, i

143 The effectiveness of LEOPARD is validated on four real-world omics datasets c

144 ve recognized Panthera species (lion, tiger, leopard, jaguar, and snow leopard).

145 Mutations in leopard (leo), encoding Connexin 41.8 (Cx41.8), a gap ju

146 r than in other big cats, including the Amur leopard, likely because of an exceptionally high effecti

147 ght the remarkable resilience of the African leopard, likely because of its extraordinary habitat ver

148 ies of big cats, including tigers, cheetahs, leopards, lions, snow leopards, and jaguars, are protect

149 linically similar but distinctive disorders, LEOPARD (LS) and Noonan (NS) syndromes.

150 We further argue that leopards may select smaller-sized prey than predicted by

151 survival and residual reproductive value of leopard mothers against the benefits derived from matern

152 Leopard mothers appear sensitive to their offspring's de

153 man-wildlife conflicts, we used GPS data for leopards (N = 6) to identify behavioral states and docum

154 he 37 living species of Felidae, the clouded leopard (Neofelis nebulosa) is generally classified as a

155 tiger (Panthera tigris altaica) and clouded leopard (Neofelis nebulosa).

156 ed a web-based classifier trained on clouded leopard (Neofelis spp.) skulls from museum collections a

157 Clouded leopards (Neofelis spp.), a morphologically and ecologic

158 The clouded leopard, Neofelis nebulosa, is an endangered semiarborea

159 be saved and survival prospects for the Amur leopard not only in China, but also through imperative c

160 pulation genetic variation among 109 clouded leopards of known geographic origin (Figure 1A, Tables S

161 riable roaring phrases, when confronted with leopards or crowned eagles.

162 sting vocalizations of their main predators, leopards or eagles.

163 Our results further suggest that Asian leopards originated from a single out-of-Africa dispersa

164 he leopard (Panthera pardus, 81% loss), snow leopard (P. uncia, 38%), wolf (Canis lupus, 77%) and dho

165 is; snow leopard, P. uncia; jaguar, P. onca; leopard, P. pardus; and lion, P. leo.

166 nthera genus species: tiger, P. tigris; snow leopard, P. uncia; jaguar, P. onca; leopard, P. pardus;

167 estimate density for the endangered Persian leopard Panthera pardus saxicolor in three montane natio

168 ween apex carnivores (wolf Canis lupus, snow leopard Panthera uncia, Eurasian lynx Lynx lynx) and mes

169 Leopards Panthera pardus exhibit a unique form of short-

170 used observations of 2,960 kills made by 49 leopards Panthera pardus in the Sabi Sand Game Reserve,

171 lupus and vertical-ambushing, stalking snow leopards Panthera uncia.

172 the African lion (Panthera leo leo), African leopard (Panthera pardus pardus), and cheetah (Acinonyx

173 In South Africa, leopard (Panthera pardus) population decreases are thoug

174 , puma (Puma concolor), lion (Panthera leo), leopard (Panthera pardus), and Pallas' cat (Otocolobus m

175 anthera tigris), cheetah (Acinonyx jubatus), leopard (Panthera pardus), lion (Panthera leo), snow leo

176 t the wide distribution range retreat of the leopard (Panthera pardus, 81% loss), snow leopard (P. un

177 (Panthera pardus), lion (Panthera leo), snow leopard (Panthera uncia), and jaguar (Panthera onca) in

178 ay wolves (Canis lupus; n = 133) and Persian leopards (Panthera pardus tulliana; n = 40) reported by

179 ies in southern Africa-lions (Panthera leo), leopards (Panthera pardus), African wild dogs (Lycaon pi

180 daily and seasonal activity patterns of snow leopards (Panthera uncia) are poorly understood, limitin

181 ntrolled conditions in which 16 captive snow leopards (Panthera uncia) were camera-trapped on 40 occa

182 Our findings demonstrate that leopards persist at a moderate density (2.21 /100 km(2))

183 But despite their ubiquity, leopard phylogeography and population history have not y

184 y overlap was observed between wolf and snow leopard (Pianka's index = 0.892) and Pallas's cat and Ti

185 n catfish Pterygoplichthys disjunctivus, and leopard pleco P. gibbiceps, reached very high-risk statu

186 Focusing on a snow leopard population in the Qilian mountains of Gansu Prov

187 lleles into Middle Eastern and Central Asian leopard populations within the last 100,000 years.

188 our ability to document and monitor clouded leopard populations.

189 Although leopard prey access was not affected by humans, lion and

190 genera Profelis (serval) and Panthera (snow leopard) provides further evidence for karyotypic conser

191 and MITF), Kallmann (CHD7 and SOX10), Noonan/LEOPARD (PTPN11), CHARGE (CHD7), or Kabuki (KMT2D).

192 ngs confirm secondary outcomes of the recent LEOPARD RCT.

193 Despite an increase in energetic gain, leopard reproductive success declined significantly duri

194 will intensify seasonal effects on the snow leopard's daily temporal niche for thermoregulation in t

195 de and developed a distribution model of the leopard's historical range in northeastern China over th

196 metric analysis of the pelages of 57 clouded leopards sampled throughout the species' range.

197 exual organisms as examples: ravens, spotted leopards, sea butterflies, and liverworts.

198 dings suggest high individual variability in leopard seal behavior regarding site fidelity and social

199 However, little is known about leopard seal haul out site fidelity and social behavior.

200 ity and social structure at Cape Shirreff, a leopard seal hotspot during austral summers.

201 Such low survival may be driven by leopard seal Hydrurga leptonyx predation, particularly p

202 Interestingly, the mother leopard seal identified through our relatedness analyses

203 (GOA), Spotted Hyena Optimization (SHO) and Leopard seal optimization (LSA)- Extreme Gradient Boosti

204 Our results suggest that without leopard seal predation, this population would most likel

205 The estimated information entropy of the leopard seal songs is comparable to nursery rhymes but u

206 polymorphism (SNP) dataset obtained from 88 leopard seal tissue samples to investigate patterns of s

207 The greater structure of the leopard seal's song improves the ability of distant list

208 As top predators, leopard seals (Hydrurga leptonyx) have a key role in Sou

209 During their breeding season, male leopard seals (Hydrurga leptonyx) spend hours perfecting

210 s produced by 26 different Eastern Antarctic leopard seals have less predictable temporal structure t

211 Most leopard seals were unrelated, but we identified a trio o

212 made up of discrete call types common across leopard seals within a region, which begs the question -

213 This condition is most evident in leopard seals, which have well-integrated foreflippers w

214 From the resource selection models, we found leopards selected habitats with dense to moderate vegeta

215 risk of human-leopard conflicts is highest, leopards selected tea plantations, forest patches but av

216 f a kill being kleptoparasitized varied with leopard sex and age, prey size and vulnerability, vegeta

217 of a representative cartilaginous fish, the leopard shark, Triakis semifasciata.

218 ed GPS-collars with activity loggers to snow leopards, Siberian ibex (Capra sibirica: their main prey

219 rs to correctly assign provenance to clouded leopard skulls with uncertain origins.

220 the European round back slug (Arionidae) and leopard slug (Limacidae) and to establish an imaging pro

221 These pigment clumps produced a striking leopard-spot pattern on fundus autofluorescence imaging.

222 We have generated iPSCs from patients with LEOPARD syndrome (an acronym formed from its main featur

223 Multiple lentigines/LEOPARD syndrome (LS) is a rare, autosomal dominant diso

224 LEOPARD syndrome (LS) is an autosomal dominant "RASopath

225 aling is exemplified by the observation that LEOPARD syndrome (LS) patients possess inactivating PTPN

226 In LEOPARD syndrome (LS) patients, mutations in the protein

227 LEOPARD syndrome (multiple Lentigines, Electrocardiograp

228 1 mutations causing other diseases including LEOPARD syndrome and leukemias.

229 of cardiomyocytes derived from patients with LEOPARD syndrome and LQTS has shed light on the molecula

230 ome cases, and PTPN11 mutations cause 90% of LEOPARD syndrome cases.

231 juvenile myelomonocytic leukemia (JMML) and LEOPARD syndrome frequently carry a second, somatically

232 ow that in vitro-derived cardiomyocytes from LEOPARD syndrome iPSCs are larger, have a higher degree

233 A major disease phenotype in patients with LEOPARD syndrome is hypertrophic cardiomyopathy.

234 ns increase SHP2 phosphatase activity, while LEOPARD syndrome mutants are catalytically impaired, rai

235 How do catalytically impaired LEOPARD syndrome mutants engender gain-of-function pheno

236 Our study reveals that LEOPARD syndrome mutations weaken the intramolecular int

237 ndicate that previously enigmatic aspects of LEOPARD syndrome pathogenesis can be explained by the co

238 derived from a healthy brother of one of the LEOPARD syndrome patients.

239 bryos with those injected with mRNA encoding LEOPARD syndrome point mutations, we identify a phosphat

240 Consequently, LEOPARD syndrome SHP2 mutants bind upstream activators p

241 2 mutants are constitutively active, whereas LEOPARD syndrome SHP2 mutants exhibit reduced phosphatas

242 individuals) and two of six individuals with LEOPARD syndrome without PTPN11 mutations have missense

243 ) caused by Danon disease, Vici syndrome, or LEOPARD syndrome, but not in HCM caused by mutations in

244 Noonan and LEOPARD syndromes are developmental disorders with overl

245 ermline mutations in PTPN11 cause Noonan and LEOPARD syndromes, which have overlapping clinical featu

246 f leopards are based on the Far Eastern Amur leopards that live at the extremity of the species' dist

247 Female leopards that suffered higher rates of kleptoparasitism

248 seasons (spring through winter), whereas for leopards, the number of food-related and surplus predati

249 ve population size maintained by the African leopard throughout the Pleistocene.

250 st hoisting is a key adaptation that enables leopards to coexist sympatrically with high densities of

251 Inspired by the leopard tortoise's ability to passively reorient, we dev

252 a into content and temporal representations, LEOPARD transfers the temporal knowledge to the omics-sp

253 Leopards typically elicited sequences consisting of a sn

254 nd tail development, associated with clouded leopards' unique adaptations.

255 Results revealed hyenas and leopards used the underpasses more than expected whereas

256 Duration of care exhibited by female leopards varied markedly, from 9 to 35 months.

257 The population densities of leopards vary widely across their global range, influenc

258 sk-reducing effect for argali vis-a-vis snow leopards was lacking.

259 Snow leopards were facultatively nocturnal with season-specif

260 ion to: (1) darkness as concealment for snow leopards when stalking in an open landscape (nocturnal a

261 rd genome assembly, as well as two wild Amur leopard whole genomes.

262 s between the Siberian tiger and the clouded leopard with 93% accuracy.

263 rence data of the critically endangered Amur leopard worldwide and developed a distribution model of

264 ds, such as missForest, PMM, GLMM, and cGAN, LEOPARD yields the most robust results across the benchm