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1 R-specific events, not SC formation, at late leptotene.
2 ted by Spo11-dependent DSBs that form during leptotene.
3 pt that in this case Rad51 was detectable at leptotene.
4 n of AtMSH5 to meiotic chromosomes occurs at leptotene and is dependent on DNA double-strand break fo
8 ated extensively with chromatin loops during leptotene and zygotene and showed preferential binding i
9 became particularly enriched during meiotic leptotene and zygotene in germline chromatin of Tetrahym
11 The number of DNA breaks detected rose as leptotene and zygotene spermatocytes populate the testis
14 nscription of genes that are markers for the leptotene and zygotene stages, but not genes that are ma
15 tages of germ cells at early meiotic stages (leptotene and zygotene) but lower percentages at later s
16 found in wild type (WT) meiosis during late leptotene and zygotene, was missing in the ask1-1 mutant
17 oposal: Group II organisms use the repair of leptotene breaks to promote synapsis by generating doubl
18 d breaks, detected by proxy as RAD51 foci at leptotene, but only ~2.3% of these sites mature into chi
19 y a two-step transcriptome reorganization in leptotene, during which 26.7% of transcripts changed in
20 taposition of homologous chromosomes at late leptotene/early zygotene are essential steps before chro
21 lustering) at the nuclear periphery in early leptotene, leading to formation of the telomere bouquet.
22 oz1 mutant meiocytes, chromosomes maintain a leptotene-like state and never compact to a zygotene-lik
26 g" of the BTB above a migrating preleptotene/leptotene spermatocyte and the "resealing" of the barrie
27 ccommodate the migration of preleptotene and leptotene spermatocytes across the BTB during spermatoge
29 stis barrier (BTB) to migrating preleptotene/leptotene spermatocytes at stage VIII of the epithelial
30 enesis in the mammalian testis, preleptotene/leptotene spermatocytes differentiate from type B sperma
36 mble their AEs, and arrested as early as the leptotene stage of prophase I, demonstrating that cohesi
39 and is manifest at spermatogonia and/or pre-leptotene-stage cells, which facilitates PRDM9 binding a
42 e course of meiosis showed that the onset of leptotene, the first stage of prophase I, frequently occ
44 assed through premeiotic interphase and into leptotene, there was an increase in the frequency of lar
47 rinsic affinity for chromosome axes at early leptotene, where it localizes independently of recombina
48 estis with a peak at day 14 postpartum, when leptotene, zygotene, and early pachytene spermatocytes a
49 it regulates the transition through a novel leptotene-zygotene checkpoint, a key step in early meiot
51 e II activity that are initially detected in leptotene-zygotene spermatocytes just preceding the form
52 Telomeres associate with the NE during the leptotene-zygotene transition but cluster slowly if at a
53 tromeres vs. telomeres in the nucleus at the leptotene-zygotene transition is the same in mutant and
54 BR2(-/-) spermatocytes were arrested between leptotene/zygotene and pachytene and died through apopto
55 matogenesis of normal mice, where only a few leptotene/zygotene spermatocytes I with clustered telome
56 nes and proteins in enriched preparations of leptotene/zygotene spermatocytes, prepubertal and adult
57 m cells undergo cytological arrest in a late-leptotene/zygotene stage, they nevertheless develop gene
59 ope to transiently form a cluster during the leptotene/zygotene transition (bouquet arrangement).
61 contrast, Hop1 plays a critical role at the leptotene/zygotene transition which is defined by transi
62 ic block in an early meiotic prophase state (leptotene/zygotene) in mutant germ cells, and identified