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1 elial cells), CD14 (monocytes) and CD45 (pan-leucocytes).
2 crease in sputum neutrophils and circulating leucocytes.
3 ely via its inhibitory effects on phagocytic leucocytes.
4 d to vascular endothelial cells and invading leucocytes.
5 sequently confirmed by enzyme measurement on leucocytes.
6 s differ quite radically from those in other leucocytes.
7 heir ability to bind and recruit circulating leucocytes.
8 y to induce migration of specific subsets of leucocytes.
9 lysis of reverse transcribed mRNA from blood leucocytes.
10 ve better imaging results than radiolabelled leucocytes.
11 howed the same Y-chromosome deletion seen in leucocytes.
12 otic niche and enhance the transmigration of leucocytes.
13 enol-soluble modulins (PSMs), by circulating leucocytes.
14 ion, and with elevated counts of circulating leucocytes.
15 kemia cells) and do not affect non-malignant leucocytes.
16 elial swelling with occasional intravascular leucocytes.
17 us-induced ER stress and type I IFN in human leucocytes.
18 erism of recipient-derived and donor-derived leucocytes.
19 WGS was performed in tumour and leucocytes.
20 odern studies on eosinophils and other blood leucocytes.
21 ined the PRLR sequence in 50 DNA samples (35 leucocytes, 15 tumors) from 46 prolactinoma patients (59
22 t included the presence of symptoms, urinary leucocytes, a positive urine culture, and symptom resolu
23 mopoietic cells, including immune-modulating leucocytes, a prerequisite of the tolerance induction st
26 y contribute to the increased trafficking of leucocytes across the blood-brain barrier as seen in cer
28 c factors, since they are also implicated in leucocyte activation, angiogenesis, and antimicrobial fu
29 thelial Growth Factor Receptor-1(VEGF-1) and leucocyte activation/inflammation-Resistin, Neutrophil G
31 terized by reduced plasma leakage, decreased leucocyte adhesion and ameliorated lung pathology, culmi
33 ition of PATs attenuates barrier leakage and leucocyte adhesion induced by endothelial junction hyper
34 dep) display blunted barrier dysfunction and leucocyte adhesion, whereas leucocytes from these mice d
36 xpression was significantly reduced in blood leucocytes and ASM obtained from patients with asthma co
44 isease bound twice as many polymorphonuclear leucocytes and U937 cells as endothelial cells from unin
45 assessed HIMEC binding to polymorphonuclear leucocytes and U937 cells by means of an adhesion assay.
46 of the NK8(+) signature in peripheral blood leucocytes and validate their association with clinical
47 lood eosinophil count (<2% vs >/=2% of blood leucocytes) and whether or not patients had received inh
48 T cells, reduced MHC II expression on blood leucocytes, and a modest increase in bone marrow residen
49 890) and telomere length in peripheral blood leucocytes, and assessed their associations with chronic
50 re regulated general metabolism processes in leucocytes, and miRNA altered in remission are involved
51 current study was to investigate whether dog leucocyte antigen (DLA) class II alleles and haplotypes
55 4 and SACM2L) and a thus far unnoticed human leucocyte antigen (HLA) class II pseudogene, termed HLA-
58 T-cells is influenced by the level of human leucocyte antigen (HLA) expression to determine hypersen
61 that germline and somatic reduction of human leucocyte antigen (HLA) heterogeneity enhances the risk
63 s been active debate about the role of human leucocyte antigen (HLA) matching in kidney allograft sur
65 to the Smith (Sm) autoantigen and the human leucocyte antigen (HLA)-DR15 haplotype; hence, we invest
66 ls were used to evaluate the effect of human leucocyte antigen (HLA)-DR2 (DRB1*1501, DQB1*0602) on cl
69 genetic quality tests on GMP-compliant human leucocyte antigen (HLA)-homozygous hiPSCs and their deri
70 disease (GVHD) after non-myeloablative human leucocyte antigen (HLA)-matched, unrelated donor, alloge
71 e conformational landscapes of peptide/human leucocyte antigen (pHLA) protein complexes encompassing
72 protein 2 (LMP2), in association with human leucocyte antigen A24, to treat therapy-refractory Epste
74 ation, and de novo donor-specific anti-human leucocyte antigen antibodies (dnDSAs) have been associat
79 DC dysfunction, characterized by lower human leucocyte antigen DR expression and reduced interleukin
81 ce of the role of environmental and nonhuman leucocyte antigen genetic factors in coeliac disease.
83 isms and ulcerative colitis associated human leucocyte antigen haplotypes are not associated with pri
84 dverse drug reactions (cADRs), such as human leucocyte antigen HLA-B*15:02, HLA-A*31:01 variants.
85 eceptor (TCR) and peptide presented by human leucocyte antigen molecule is a highly challenging task
89 1 psoriasis is strongly linked to the human leucocyte antigen-Cw6, recent genetic studies have sugge
92 urvivals of 65-75% are achievable with human leucocyte antigen-matched related and unrelated donors.
93 ed with comparable survival to that of human leucocyte antigen-matched URD transplantation in childre
94 nd resistance are associated with both human leucocyte antigen-related and unrelated genetic factors.
96 atients with circulating antibodies to human leucocyte antigens (anti-HLA) are highly sensitised agai
97 t their differentiated progeny express human leucocyte antigens (HLAs) that will probably cause graft
98 aving potential fusion neoantigens and human leucocyte antigens (HLAs), fusion breakpoint RNA/protein
100 ibutable to variants in genes encoding human leucocyte antigens, only about a quarter of reported her
102 ation can promote heart failure, positioning leucocytes as central protagonists and potential therape
103 hronic lymphocytic leukaemia cell per 10 000 leucocytes as measured by four-colour flow cytometry), a
104 immunoglobulin-like receptor B1 (LILRB1) or leucocyte-associated immunoglobulin-like receptor 1 (LAI
110 riant in the mother was assessed in DNA from leucocytes, buccal cells and hair follicles using target
111 ced pleurisy, dominated by polymorphonuclear leucocytes, but may aid resolution at the later, mononuc
112 xpression could readily be detected in blood leucocytes by PCR analysis in all control samples but no
116 clock, GrimAge, and PhenoAge) and estimated leucocyte compositions were generated using Horvath's Ne
117 fied variables (initial nonShockable rhythm, Leucocyte count < 4 or > 12 K/muL after targeted tempera
118 ory of heart failure (OR, 1.43 [1.01-2.03]), leucocyte count </=72 hours after TAVI (OR, 1.05 [1.02-1
119 s 158 [25%] in the control group), decreased leucocyte count (103 [16%] vs 74 [20%]), fatigue (81 [13
120 5% CI 11.3 to 28.8; p<0.0001), increased CSF leucocyte count (2.01 per 5 cells per muL, 1.61 to 2.39;
122 arlson comorbidity index, haemoglobin count, leucocyte count, creatinine levels, cause of perforation
123 ate analysis, means of parameters like total leucocyte count, urea, bilirubin, alanine transaminase,
126 is suggested a 6.3% to 11.5% contribution of leucocyte counts in the association of blood Cd and Pb l
127 iodontal therapy on arterial blood pressure, leucocyte counts, fibrinogen, tissue necrosis factor-a,
128 esulted in increased migration/activation of leucocytes crossing the 22qDS+schizophrenia blood-brain
129 recombinant IL-1beta in primary head kidney leucocyte cultures and RTS-11 cells, a macrophage cell l
132 transcriptomic analysis of peripheral blood leucocytes defines two distinct sepsis response signatur
135 Here we show that the packaging of mRNA into leucocyte-derived EVs and the endocytosis of the EVs by
137 cteria tuberculosis chaperonin 60.1 inhibits leucocyte diapedesis and bronchial hyperresponsiveness i
138 n interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antige
140 th was calculated by in-gel hybridisation to leucocyte DNA from 56 normal individuals aged 0-96 years
142 leucocyte DNA were detected, we also tested leucocyte DNA from the individuals' fathers, and in one
143 ave shown in a large case-control study that leucocyte DNA hypomethylation is associated with increas
144 er mL, we detected Y-chromosome deletions in leucocyte DNA similar in location to those previously re
145 he two men in whom Y-chromosome deletions in leucocyte DNA were detected, we also tested leucocyte DN
147 Screening this library for binding to human leucocyte elastase identified sequences with a strong co
150 helial damage, innate immune activation, and leucocyte-endothelial interactions in the pathology of s
153 mental stress rapidly amplifies inflammatory leucocyte expansion inside mouse atherosclerotic lesions
154 When selected growth factors were added, leucocytes expressing CD45 were generated and released i
162 that the RNA sequences in high abundance in leucocytes from chronic granulocytic leukaemias differ q
164 osure leads to prompt uptake of inflammatory leucocytes from the blood to distinct tissues including
165 dysfunction and leucocyte adhesion, whereas leucocytes from these mice did not show altered adhesive
166 cells, the interaction of the beta2 integrin leucocyte function-associated antigen-1 (LFA-1) with its
167 and thus evaluated the relationship of blood leucocyte gene expression to progression of cerebral whi
170 ing genetic variants at specific loci, human leucocyte (HLA) haplotypes, or the blood innate immune r
172 ound that a subset of RIFINs binds to either leucocyte immunoglobulin-like receptor B1 (LILRB1) or le
173 by lipopolysaccharide (LPS) stimulated human leucocytes in order to provide an initial structure-acti
175 le mice exhibit a reduction in the number of leucocytes in the lung lumen when challenged with OVA an
177 Specifically, OSM, expressed by CD45(+) leucocytes in the stromal vascular fraction, induced pho
178 endritic cells (DCs), recruited inflammatory leucocytes, including APCs in mice, and promoted antigen
179 arge vessel disease that is characterized by leucocyte infiltration and lipid deposition in the wall
181 e disease in MRL-lpr mice is associated with leucocyte infiltration into the choroid plexus, brain ce
184 iated with a marked reduction in ICH-induced leucocyte infiltration, microglia/macrophage activation
186 negative breast cancer (TNBC) often exhibits leucocyte infiltrations that correlate with favorable pr
187 sion of proinflammatory molecules, decreased leucocyte inflammation, and significantly improved graft
188 tically, we found that acute stress enhances leucocyte influx into mouse atherosclerotic plaques by m
189 le-1 (ICAM-1) functions via its ligands, the leucocyte integrins, in adhesion of immune cells to endo
190 ytokines seem able to attract HIV-1-infected leucocytes into the amniotic cavity and to increase repl
192 se interaction between endothelial cells and leucocytes is a key regulatory step in the inflammatory
196 icating genes involved in the 'regulation of leucocyte/lymphocyte activity' and also 'cytokine-mediat
198 esis-characterized by significantly elevated leucocyte (mainly neutrophil and monocytes) and erythroc
199 iological turnover of erythrocytes and other leucocytes, making it the most abundant form of cell dea
200 active oxygen species from polymorphonuclear leucocytes may be potential inducers of the RprY regulon
203 and BtSULT homologues in bacteria inhibited leucocyte migration in vitro and in vivo, and abundances
204 ephrine signalling diminished stress-induced leucocyte migration into mouse atherosclerotic plaques.
208 C-030031 treatment also dramatically reduced leucocyte numbers and IL-8 level in the BAL fluid, inhib
209 tic-like response: bronchial-alveolar lavage leucocyte numbers, Muc5ac and Muc5b mRNA levels, and Cla
211 to distinguish clearly the peripheral blood leucocytes of chronic granulocytic leukaemias from other
212 ther the GCase activity level was altered in leucocytes of these subjects and how it was related to d
213 g a sensitive KIT mutation analysis of blood leucocytes or measurement of urinary histamine metabolit
214 genome-wide studies in ARDS use total blood leucocytes; our study is the first, to our knowledge, to
215 ecreased FMRP expression in peripheral blood leucocytes over the same repeat range, despite a slight
220 CMV pp65 antigen positive polymorphonuclear leucocytes (PMNLs) per 200 000 cells previously reported
221 we demonstrated that blood polymorphonuclear leucocytes (PMNs) in ARDS are basally activated, and exh
222 mRNA from human polymorphonuclear neutrophil leucocytes (PMNs) was probed with cDNA encoding human sk
223 aired defense functions of polymorphonuclear leucocytes (PMNs), increased patient susceptibility to i
225 d RNAs of a variety of normal and neoplastic leucocyte populations showed that the RNA sequences in h
227 epresenting the RNAs of normal and leukaemic leucocyte populations were sufficiently different to dis
229 including the presence of symptoms, urinary leucocytes, positive urine culture and symptom resolutio
230 pithelial barrier and may then interact with leucocytes, potentially inducing proinflammatory respons
231 or their ability to inhibit murine and human leucocyte proliferation and TNF-alpha secretion by lipop
233 clude PLC-gamma2, Syk, SH2-domain-containing leucocyte protein of 76 kDa (SLP-76), Lyn, linker for ac
234 NE and Cat G selective inhibitor, secretory leucocyte proteinase inhibitor, reduction of the enhance
235 hide core domain proteins, such as secretory leucocyte proteinase-1 (SLP-1), but the Trichuris protei
238 tor cells), cytochemical staining, and mixed leucocyte reactions to determine the functional capacity
239 gnaling from inflammatory PT cells mediating leucocyte recruitment and myofibroblast activation.
240 lung inflammation through a dual function in leucocyte recruitment and tissue remodelling and may rep
241 Here we describe a more rapid mechanism of leucocyte recruitment to the site of intrusion of the im
243 novirus-induced ORMDL3 expression in primary leucocytes required cell-cell contact, and induction was
245 ing eosinophil counts of 2% or more of blood leucocytes respond better to inhaled corticosteroids tha
246 uantum yield (approximately 0.98), and human leucocyte-specific monoclonal antibodies (CD3, CD4, and
250 egulation of DNA methylation-based estimated leucocyte subsets towards more differentiated T-cell phe
252 roscopy and flow cytometry of graft-specific leucocyte surface marker CD45 and macrophage marker CD68
255 hazard ratio; 95% CI 1.27 for a doubling of leucocyte telomere length at baseline; 1.05-1.44] than p
260 estigate whether patients with various blood leucocyte telomere lengths had different overall surviva
262 muscle use can stimulate muscle invasion by leucocytes that have the potential to increase tissue da
263 latelets and other cells (endothelial cells, leucocytes) that contribute to an inflammatory response,
264 o-immunized with their partners' mononuclear leucocytes to prevent spontaneous recurrent abortion.
265 Vs by neurons can be enhanced by engineering leucocytes to produce EVs that incorporate retrovirus-li
266 d capillary blood flow caused by adhesion of leucocytes to the brain microvascular endothelium leads
267 AM-1 mediates adhesion and transmigration of leucocytes to the vascular endothelial wall, a step prop
268 remission dynamics of MS in peripheral blood leucocytes, to shed light on the molecular and regulator
270 mutant resulted in reduced polymorphonuclear leucocyte transepithelial migration and mitogen-activate
271 rotein kinase pathways and polymorphonuclear leucocyte transepithelial migration associated with Shig
272 ORMDL3, HSPA5 and IFNB1 expression varied by leucocyte type and 17q21 genotype, with the highest expr
274 of the activity of the sodium pump of human leucocytes was used to test each fraction for the presen
275 ease negativity (cutoff 4 x 10-5 bone marrow leucocytes) was achieved in 55% of patients tested in th
277 erived from endothelial cells, monocytes and leucocytes were at concentrations similar to baseline in
278 ukin 1 and cytokine mRNA in peripheral-blood leucocytes were not raised, but amounts of interleukin 1
279 inoma patients' peripheral blood mononuclear leucocytes were stimulated in vitro with autologous tumo
280 inant cells at 2 hours are polymorphonuclear leucocytes, whereas mononuclear cells dominate from 24 h
281 , followed by tissue destruction mediated by leucocytes which clinically cause significant destructio
282 tiated T-cell phenotypes and proinflammatory leucocytes, which was also partly restored with ART.
283 immortalized and primary bone-marrow-derived leucocytes with DNA or RNA encoding the capsid-forming a