ライフサイエンスコーパス: limbal

1 (29%) underwent living-related conjunctival limbal allograft and 10 eyes (71%) underwent cadaver-don

2 ance with impression cytology, and to detect limbal alterations associated with partial or total conj

3 epithelial stem cells, are detected in both limbal and central cornea of mouse eye.

4 Side-population (SP) cells isolated from limbal and conjunctival epithelia derive from cells that

5 em cells are present throughout the corneal, limbal and conjunctival epithelia.

6 the stratified but non-keratinized corneal, limbal and conjunctival epithelium, in concert with the

7 n of transcriptional coactivator YAP1 in the limbal and corneal basal epithelial cells and its essent

8 Limbal and corneal epithelia from wild-type FIH-1(-/-) a

9 ip between FIH-1 and c-kit as it pertains to limbal and corneal epithelial glycogen stores.

10 in developing corneal stroma and a subset of limbal and corneal stromal progenitors, we examined the

11 ly in CD-1 mice by laser photocoagulation of limbal and episcleral veins 270 degrees to 300 degrees c

12 Laser photocoagulation of limbal and episcleral veins induces transient ocular hyp

13 ly in CD-1 mice by laser photocoagulation of limbal and episcleral veins.

14 cular history, best-corrected visual acuity, limbal anterior chamber depth assessment, frequency-doub

15 <7 months of age by the same surgeon using a limbal approach.

16 Ophthalmologic findings included loss of limbal architecture, a whorl-like epitheliopathy, or an

17 noted in the bulbar conjunctiva and near the limbal area of corneas from NK1R(-/-) mice.

18 eity of preexisting lymphatic vessels in the limbal area significantly correlated with the extent of

19 vessels are not evenly distributed in normal limbal areas.

20 c vessels in the nasal side in normal murine limbal areas.

21 ated with physiological parameters, that the limbal attachment can cause small (<20%) increases in TM

22 inner hair cell stimulation, and reveal the limbal attachment of the TM plays a critical role in thi

23 impedance of the tectorial membrane and its limbal attachment.

24 ygium excision compared with conjunctival or limbal autograft or mitomycin C alone.

25 tudies demonstrated that the conjunctival or limbal autograft procedure is more efficacious than amni

26 Conjunctival or limbal autograft was superior to amniotic membrane graft

27 The outcomes of conjunctival or limbal autograft were similar to outcomes for intraopera

28 , where pterygium excision with conjunctival-limbal autograft with fibrin glue application was done.

29 that using a combination of conjunctival or limbal autograft with mitomycin C further reduces the re

30 paring bare sclera excision, conjunctival or limbal autograft, intraoperative mitomycin C, postoperat

31 Use of conjunctival or limbal autografts or mitomycin C during or after pterygi

32 vidence that mitomycin C and conjunctival or limbal autografts reduce the recurrence rate after surgi

33 on markers, that is, K3 and K12 keratins, in limbal basal cells (these markers are expressed, however

34 lusive location of slow-cycling cells in the limbal basal layer, the superior in vitro proliferative

35 mber 7 months post-operatively and a case of limbal-based conjunctival dissection during open revisio

36 To compare effectiveness of fornix- and limbal-based conjunctival flaps in trabeculectomy surger

37 shallow anterior chamber was observed in the limbal-based group.

38 anterior chamber, which was increased in the limbal-based group.

39 In the fornix-based and limbal-based surgery, mean IOP at 12 months was similar,

40 ich benefits and complications of fornix- vs limbal-based trabeculectomy for glaucoma were compared i

41 nce in effectiveness between fornix-based vs limbal-based trabeculectomy surgery, although with a hig

42 , -gamma1, -gamma2 and -gamma3 chains in the limbal basement membrane, with LN-alpha5 representing a

43 Limbal biopsies were obtained from the contralateral eye

44 t, common culture approaches, outgrowth from limbal biopsy explants and isolated cell seeded in low c

45 mary surgery all patients underwent a repeat limbal biopsy from the unaffected eye.

46 omes are similar irrespective of whether the limbal biopsy is taken from the healthy part of the ipsi

47 A 1-clock hour limbal biopsy sample was obtained from the unaffected ey

48 After a limbal biopsy specimen obtained from a healthy area of t

49 The limbal biopsy was taken either from the healthy part of

50 In 34 eyes the limbal biopsy was taken from the ipsilateral eye and in

51 appeared to be involved in the formation of limbal blood vessels and corneal nerve fibers.

52 corneal limbus and became distributed around limbal blood vessels.

53 use the lymphatic vessel architecture at the limbal border of the normally avascular cornea, a quanti

54 with an astigmatic neutral manual posterior-limbal cataract incision.

55 Limbal cells obtained from the superior limbus, isolated

56 The limbal cells were expanded ex vivo on a human amniotic m

57 Limbal cells were harvested from healthy or less affecte

58 imbal epithelial cells, and the transplanted limbal cells' ability to reconstitute corneal epithelium

59 istorical controls, including mean number of limbal clock hours affected by OSSN (6 vs 4; P = .12), m

60 single tumor >/=15 mm basal diameter or >/=6 limbal clock-hours) was managed with topical IFNalpha2b

61 Limbal conjunctival autograft was more effective than in

62 03), which in turn was less than the size of limbal conjunctival epithelial defect (7.3+/-5.1 clock h

63 phs were used to determine the extent of any limbal conjunctival epithelial defect and ischemia.

64 found between visual outcome at 3 months and limbal conjunctival fluorescein staining (r = 0.67, P =

65 eyes) with sutures (74 eyes) for closure of limbal conjunctival incisions in patients undergoing str

66 at the off-label use of fibrin glue to close limbal conjunctival incisions in strabismus surgery resu

67 uorescein staining (r = 0.67, P = .006), and limbal conjunctival ischemia on OCTA (r = 0.76, P = .001

68 autograft group and 1 patient (1.0%) in the limbal-conjunctival autograft group developed recurrence

69 ctival autograft group and 105 eyes from the limbal-conjunctival autograft group).

70 junctival autograft transplant (112 eyes) or limbal-conjunctival autograft transplant (112 eyes).

71 Limbal-conjunctival autografts could be a favored option

72 Limbal-conjunctival transplant is safe and more effectiv

73 for his description of the eponymously named limbal corneal pits as a sign of trachoma.

74 Peripheral and limbal corneal stromal cells (PLCSCs), which contain ker

75 Limbal, corneal, and/or scleral involvement were present

76 Limbal damage was seen in some eyes with CLAU.

77 in outcomes were: goblet cell density (GCD), limbal dendritic cell density (LDCD), subbasal corneal n

78 epithelium was completely replaced by K14(+) limbal-derived clones, an observation supported by high-

79 Main diagnoses were corneal scar (22.9%), limbal dermoid (21.9%), anterior segment dysgenesis (15.

80 Other associated ophthalmic features were limbal dermoids (2 cases), lateral canthal coloboma (3 c

81 describe the in vivo confocal morphology of limbal dermoids in Goldenhar syndrome and (ii) compare t

82 that IVCM may be a useful technique to study limbal dermoids, given its ability to detect typical mic

83 121 children with VKC, 119 (98.4%) had only limbal disease.

84 Corneoscleral limbal dissection of >/=6 clock hours during wide excisi

85 mean number of clock hours of corneoscleral limbal dissection owing to wide tumor excision (8 vs 7;

86 D in cases requiring extensive corneoscleral limbal dissection.

87 Both corneal and limbal epithelia become progressively thinner in LSCD.

88 stigate the contributions of the corneal and limbal epithelia in angiogenic and lymphangiogenic privi

89 ment, is expressed in post-natal corneal and limbal epithelia progenitors (LEPC) but not in underlyin

90 ed in all layers of the corneal and anterior limbal epithelia.

91 ls were present in the central and posterior limbal epithelia.

92 minantly resolved by centripetally migrating limbal epithelia.

93 rental strain RN6390 to apical human corneal-limbal epithelial (HCLE) cells and to biotinylated cell

94 ry and telomerase immortalized human corneal limbal epithelial (HCLE) cells impacts their migration a

95 cytotoxicity in coculture with human corneal limbal epithelial (HCLE) cells, primary human corneal fi

96 soft lithography and observed human corneal limbal epithelial cell behavior.

97 t of these topographical features on corneal limbal epithelial cell differentiation has not been expl

98 A recombinant human corneal limbal epithelial cell line expressing a LC3-GFP fusion

99 An immortalized human corneal limbal epithelial cell line was treated in the presence

100 with limbal stem cell deficiency, cultivated limbal epithelial cell transplantation improves vision a

101 ria to the autologous modality of cultivated limbal epithelial cell transplantation.

102 sments of the clinical outcome of cultivated limbal epithelial cell transplantation.

103 Human limbal epithelial cells (HLE) and corneal stromal stem c

104 iated corneal epithelial cells, and SSEA4(-) limbal epithelial cells contain a higher proportion of l

105 The limbal epithelial cells of FIH-1 null mice had an increa

106 Primary cultures of pig limbal epithelial cells stained with Hoechst 33342 were

107 ained from a healthy area of the limbus, the limbal epithelial cells were cultured on a denuded human

108 thelial cells and immortalized human corneal limbal epithelial cells were cultured on the SF and denu

109 superior in vitro proliferative potential of limbal epithelial cells, and the transplanted limbal cel

110 nces in glycogen content between corneal and limbal epithelial cells.

111 accounted for an average of 40% of the total limbal epithelial cells.

112 face (OS) epithelial tissue samples from the Limbal Epithelial Crypt (LEC), limbus, cornea and conjun

113 ate angiogenesis, we demonstrated that human limbal epithelial keratinocytes (HLEKs) engineered to ov

114 er, on the growth and differentiation of the limbal epithelial progenitor cells when these cells are

115 ifferentiation and maintain clonal growth of limbal epithelial progenitors.

116 Transplantation of limbal epithelial sheets from explant cultures is one of

117 Destruction of the limbal epithelial stem cell (LESC) population in the cor

118 rate that this difference is associated with limbal epithelial stem cell (LESC) residence and YAP-dep

119 Corneal limbal epithelial stem cell transplantation using cultiv

120 However, their roles in normal and diseased limbal epithelial stem cells (LESC) remain unknown.

121 esults solidify the essential role of K14(+) limbal epithelial stem cells for wound healing and refut

122 Limbal epithelial stem cells repopulate the donor site a

123 Limbal epithelial stem cells were isolated, and cellular

124 Optimization of culture conditions for human limbal epithelial stem/progenitor cells (LEPC) that inco

125 Co-cultivation of limbal melanocytes with limbal epithelial stem/progenitor cells on fibrin hydrog

126 ional biopsy with and without primary simple limbal epithelial transplantation (p-SLET).

127 -term clinical outcomes of autologous simple limbal epithelial transplantation (SLET), a relatively n

128 treatment (1 eye) underwent modified simple limbal epithelial transplantation at Bascom Palmer Eye I

129 ial LSCD who underwent autologous cultivated limbal epithelial transplantation between 2001 and 2011.

130 Simple limbal epithelial transplantation is probably preferable

131 ement of limbal stem cell deficiency, simple limbal epithelial transplantation seems to be a safe, re

132 Repeat autologous cultivated limbal epithelial transplantation successfully restores

133 Success of cultivated limbal epithelial transplantation, defined as a complete

134 able on the use of conventional and cultured limbal epithelium using various substrates in the treatm

135 laser-capture microdissected populations of limbal epithelium were subjected to real-time quantitati

136 IH-1 in vivo increased Notch activity in the limbal epithelium, resulting in a more differentiated ph

137 wed by mechanical debridement of corneal and limbal epithelium.

138 pact on stem/progenitor cell preservation in limbal explant cultures.

139 imary HCECs were cultured from donor corneal limbal explants and grown to subconfluence.

140 was successfully created by culturing human limbal explants at an air-liquid interface (airlift) for

141 be regenerated in cultures from central and limbal explants of murine cornea.

142 Corneal limbal explants were obtained from 2 sites, the harveste

143 eal epithelial cells, established from donor limbal explants, were treated with 11 microbial ligands

144 phenotypes: mesenchymal stem cells from the limbal eye stroma and epithelial cells from retinal pigm

145 scarring, pannus and Herbert's pits (HPs) or limbal follilcles in both eyes.

146 signs and symptoms, 48% were affected by the limbal form, 33% were affected by the tarsal form, and 1

147 ed pannus formation at the donor site of the limbal graft was noted in 5 eyes (12.8%), with the appea

148 Initial median limbal involvement was 12 clock hours (range, 3 to 12 cl

149 ty, epithelial defect area, conjunctival and limbal involvement, and injury-related complications wer

150 ctively identify and monitor the recovery of limbal ischemia following an acute ocular chemical injur

151 These were compared with the extent of limbal ischemia identified on OCTA images of the ocular

152 OCTA confirms that limbal ischemia is usually more extensive than is sugges

153 The extent of clinically determined limbal ischemia was less than that identified with OCTA

154 negative mice showed significantly increased limbal lymph vascularized areas, a higher number of lymp

155 Co-cultivation of limbal melanocytes with limbal epithelial stem/progenito

156 Limbal melanocytes, located in the basal epithelial laye

157 and cultivation of pure populations of human limbal melanocytes, which could be expanded at high yiel

158 har Syndrome showed a left, infero-temporal, limbal neoformation, with extension to the left orbital

159 olySia removal caused defasciculation of the limbal nerve trunk in vivo from E7 to E10.

160 LN) isoforms preferentially expressed in the limbal niche as culture matrices for epithelial tissue e

161 progenitors, we examined the role of Pax6 in limbal niche cells (LNC) in maintaining the phenotype of

162 livery of multiple cell types to restore the limbal niche following ocular surface injury or disease.

163 xpression patterns of LN chains in the human limbal niche provided evidence for enrichment of LN-alph

164 elf-renewal of corneal epithelial SCs in the limbal niche.

165 Limbal or cornea-specific transcripts were identified th

166 However, whether limbal or corneal vessels are evenly distributed under n

167 creased corneal thickness and degradation of limbal palisade architecture.

168 Normal limbal palisade morphology was absent in aniridia but pr

169 degree of alterations, including loss of the limbal palisades and of the normal epithelial mosaic, cy

170 OCT successfully identified the limbal palisades of Vogt that constitute the corneal epi

171 rneal conjunctivalization and anatomy of the limbal palisades of Vogt.

172 Limbal post-lens tear film gaps were present in 42% of t

173 duction, ocular surface staining, bulbar and limbal redness, tear volume, anterior blepharitis, meibo

174 red the mechanical properties of the complex limbal region effectively.

175 t immunohistochemistry were similar near the limbal region, in the central cornea the subbasal nerve

176 and four Wnt inhibitors were specific to the limbal region, whereas Wnt3, Wnt7a, Wnt7b, and Wnt10a we

177 ted miRNA expression profiles in central and limbal regions of normal and diabetic human corneas.

178 The effect of different limbal regions, enzymatic dissociation methods, and cult

179 s also detected in the clinically unaffected limbal regions.

180 through the full thickness of the cornea and limbal regions.

181 ise capsulotomy formation, clear corneal and limbal relaxing incision construction, lens fragmentatio

182 m after simultaneous phacoemulsification and limbal relaxing incisions (LRIs) performed in 2 groups o

183 Human limbal rims were acquired and imaged with OCT and confoc

184 35/492 (7%) of children had limbal signs (pannus and/or HPs) plus any conjunctival s

185 9/492 (2%) had limbal signs and moderate or severe conjunctival scarrin

186 Microarray analysis of pig limbal SP cells yielded a molecular signature underscori

187 ithelial stem cells were isolated from human limbal specimens and clonally expanded on a 3T3 feeder l

188 Plk3 in hypoxic stress-induced primary human limbal stem (HLS) and corneal epithelial (HCE) cells, re

189 e system supports enrichment and survival of limbal stem and progenitor cells during the entire culti

190 lls (Muc5AC(-)/CK19(-)) and replenishment of limbal stem cell (DeltaNp63alpha(+)/ABCG2(+)) reserve.

191 clonogenic assay, and expression of putative limbal stem cell (LSC) and corneal epithelial differenti

192 Four eyes of 2 patients developed limbal stem cell compromise confirmed with in vivo confo

193 CESCs is different from human cornea, where limbal stem cell concept has been well established and a

194 We are aware that some new evidence supports limbal stem cell concept in mouse recently.

195 l sheets has been used successfully to treat limbal stem cell deficiencies.

196 6), corneal keloid (3), chemical injury with limbal stem cell deficiency (2), and dermoid (1).

197 ciated with PED, showed diabetes (P = .006), limbal stem cell deficiency (LSCD) (P = .02), filamentar

198 ransplantation (OSST) in patients with total limbal stem cell deficiency (LSCD) owing to various etio

199 Limbal stem cell deficiency (LSCD) was diagnosed clinica

200 arization, stromal scarring, and features of limbal stem cell deficiency (LSCD) were noted on the rig

201 using various substrates in the treatment of limbal stem cell deficiency (LSCD), the patient populati

202 ed systemic PTX as a contributing factor for limbal stem cell deficiency (LSCD), which is characteriz

203 Limbal stem cell deficiency (LSCD).

204 tus post healing (grade of symblepharon, and limbal stem cell deficiency [LSCD]), and type of and nee

205 iously underwent LAT for unilateral acquired limbal stem cell deficiency after chemical burn.

206 2 years) presenting with clinical suspect of limbal stem cell deficiency and 10 eyes of 10 healthy co

207 If extensive corneal scarring and/or limbal stem cell deficiency are present, techniques such

208 atopathy, medication-related keratopathy, or limbal stem cell deficiency characterized by conjunctiva

209 ge = 42.1 years) displaying overt unilateral limbal stem cell deficiency complying with the inclusion

210 of age, with clinically diagnosed unilateral limbal stem cell deficiency following ocular surface bur

211 sity of established tools for the grading of limbal stem cell deficiency hinder objective assessments

212 yes (48.5%), nystagmus in 15 children (23%), limbal stem cell deficiency in 1 eye, cataract in 9 eyes

213 management of soft contact lens wear-related limbal stem cell deficiency in young healthy patients.

214 to 12 clock hours), resulting in a residual limbal stem cell deficiency of 6 clock hours (range, 0 t

215 Severe limbal stem cell deficiency related to CL wear is a clin

216 Database search of patients with severe limbal stem cell deficiency related to CL wear was condu

217 ilateral partial (2 eyes) and total (2 eyes) limbal stem cell deficiency secondary to ocular surface

218 Limbal stem cell deficiency was related to advancing age

219 Limbal stem cell deficiency was the most common indicati

220 No signs of limbal stem cell deficiency were observed during follow-

221 7 cases, just conjunctival epithelium (total limbal stem cell deficiency) in 5 cases, and mixed epith

222 es, and mixed epithelium in 6 cases (partial limbal stem cell deficiency).

223 r wear, symptoms, location and laterality of limbal stem cell deficiency, coexisting ocular disease,

224 al metrics demonstrate that in patients with limbal stem cell deficiency, cultivated limbal epithelia

225 d improves vision in eyes with recurrence of limbal stem cell deficiency, following failed primary su

226 y used surgical techniques for management of limbal stem cell deficiency, simple limbal epithelial tr

227 in the AMT group demonstrated corneal haze, limbal stem cell deficiency, symblepharon, ankyloblephar

228 There was no limbal stem cell deficiency, symblepharon, or diplopia n

229 ful for the noninvasive in vivo diagnosis of limbal stem cell deficiency, with a high degree of conco

230 c keratitis scarring, lipid keratopathy, and limbal stem cell deficiency.

231 atients mimicking interstitial keratitis and limbal stem cell deficiency.

232 ppression for soft contact lens wear-related limbal stem cell deficiency.

233 Some patients also showed signs of limbal stem cell deficiency.

234 is, in the eyes affected by partial or total limbal stem cell deficiency.

235 conjunctival mitomycin C injection may cause limbal stem cell deficiency.

236 OMECs) is a promising treatment strategy for limbal stem cell deficiency.

237 ultures is one of the standard treatments of limbal stem cell deficiency.

238 ence are the most promising for treatment of limbal stem cell deficiency.

239 ing to regulate c-Jun activity, resulting in limbal stem cell differentiation and center epithelial a

240 There was no relationship of limbal stem cell failure with the severity of EEC syndro

241 weeks; corneal opacification, 11%, 4 months; limbal stem cell failure, 8%, 7 months; and corneal vasc

242 ve the evaluation of outcomes after cultured limbal stem cell graft.

243 l deficiency are present, techniques such as limbal stem cell grafting, amniotic membrane transplanta

244 ess in the culture conditions also regulates limbal stem cell growth and fate.

245 e, vascularization, conjunctivalization, and limbal stem cell involvement.

246 thelial cell proliferation, differentiation, limbal stem cell maintenance, and expansion were studied

247 iation markers and higher levels of putative limbal stem cell markers.

248 g the functional roles of melanocytes in the limbal stem cell niche and their suitability for develop

249 ontribute to the identification of potential limbal stem cell niche factors that are promising target

250 As CHRDL1 is preferentially expressed in the limbal stem cell niche of adult human cornea, we assume

251 de in close proximity in vivo in the corneal limbal stem cell niche.

252 Limbal stem cell transplantation (LSCT) and Boston kerat

253 ing (n = 78), symblepharon release (n = 56), limbal stem cell transplantation (n = 26), and lamellar

254 ), conjunctival replacement surgery (COMET), limbal stem cell transplantation and kerotoprostheses.

255 Limbal stem cell transplantation is a viable option for

256 revealed 9 patients (14 eyes) who underwent limbal stem cell transplantation with systemic immunosup

257 Fourteen eyes (78%) underwent limbal stem cell transplantation with systemic immunosup

258 ve measures may not reverse the disease, and limbal stem cell transplantation with systemic immunosup

259 s probably preferable to other techniques of limbal stem cell transplantation, particularly where cel

260 At final follow-up after limbal stem cell transplantation, there was a stable ocu

261 tation (SLET), a relatively new technique of limbal stem cell transplantation.

262 Limbal stem cells (LSCs) are affected globally and basal

263 Healthy eyes contain a population of limbal stem cells (LSCs) that continuously renew the cor

264 omeostasis and regeneration are sustained by limbal stem cells (LSCs), and LSC deficiency is a major

265 c stress suppresses Plk3 activity to protect limbal stem cells from death and to allow the process of

266 aling are mainly maintained by the activated limbal stem cells originating form limbus, but not from

267 s are consistent with the notion that clonal limbal stem cells randomly activate Krt12 alleles in the

268 olds and provide biophysical cues to corneal limbal stem cells that may maintain corneal epithelial s

269 althy corneal epithelium showing survival of limbal stem cells was observed in 14 eyes (70%) during c

270 cells (CECs) undergo continuous renewal from limbal stem or progenitor cells (LSCs), and deficiency i

271 of the EEC syndrome include skin defects and limbal stem-cell deficiency.

272 the effect of Notch inhibition in the human limbal stem/progenitor cells (LSCs) in vitro by using sm

273 thelial cells contain a higher proportion of limbal stem/progenitor cells.

274 ntact lens sensor (CLS) to measure change in limbal strain associated with placing one side of the fa

275 position was associated with an increase in limbal strain in glaucoma eyes (mean [SE], 44.1 [20.4] m

276 The mean limbal strain increase among patients with glaucoma in F

277 Magnitudes of measured changes in limbal strain were greater in glaucoma eyes with past vi

278 Measured changes in limbal strain were related to estimated changes in IOP a

279 e eye shield prevents sleep position-induced limbal strains during a mean 8-hour sleep period.

280 Furthermore, this study has identified the limbal stroma as yet another MSC niche and presents a ne

281 Limbal stromal niche cells expressing SC markers can be

282 Limbal stromal niche cells heterogeneously express embry

283 tudy their effects on the differentiation of limbal stromal stem cells to keratocytes or fibroblasts

284 the organ of Corti, but is detached from the limbal surface.

285 Attempts to screen limbal tissues for suitable implants using molecular ste

286 riented flat-mount corneas together with the limbal tissues were used for immunofluorescence microsco

287 Limbal transplant survival rates at the final follow-up

288 circumferential or isolated epibulbar mass, limbal tumor, lateral canthal mass, aggregate of ectopic

289 for acquiring OCTA images of the cornea and limbal vasculature with substantial consistency.

290 lial corneal opacities and adjacent abnormal limbal vasculature, with or without pseudopterygia in 9

291 exhibit milder phenotypes, such as disrupted limbal vasculature.

292 rats by injecting hypertonic saline into the limbal venous system.

293 rats by injecting hypertonic saline into the limbal venous system.

294 In vivo imaging of limbal vessels demonstrates pericyte migration off vesse

295 Wild-type (WT) leukocytes extravasated from limbal vessels, angiogenic stalks, and growing tip vesse

296 ics that extends beyond the limits of normal limbal vessels.

297 bal vitrectomy, and eyes undergoing anterior limbal vitrectomy (P = .543).

298 Two-port anterior limbal vitrectomy was carried out after posterior capsul

299 al posterior capsulorrhexis without anterior limbal vitrectomy, and eyes undergoing anterior limbal v

300 redominately at the periphery of the cornea (limbal zone).